CERS1

GENE INFORMATION

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Gene name

CERS1 (HGNC Symbol)

Synonyms

LAG1, LASS1, UOG1

Description

ceramide synthase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.11

Chromosome location (bp)

18979361 - 19007536

Ensembl

ENSG00000223802 (version 73.37)

Entrez gene

2657

UniProt

P27544 (UniProt - Evidence at transcript level)

neXtProt

NX_P27544

Antibodypedia

CERS1 antibodies
 

PROTEIN VIEW

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CERS1-001
 
CERS1-002
 
CERS1-004
 
CERS1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CERS1-001 ENSP00000437648
ENST00000542296
Q5XG75
Show all »
Show » Show » 239 27.9 No 6
CERS1-002 ENSP00000389044
ENST00000429504
P27544
Show all »
Show » Show » 337 38 No 6
CERS1-004 ENSP00000471428
ENST00000596048
Show » Show » 216 24.7 No 5
CERS1-201 ENSP00000402697
ENST00000427170
P27544
Show all »
Show » Show » 350 39.5 No 6