APOC4-APOC2

GENE INFORMATION

? »

Gene name

APOC4-APOC2

Synonyms

Description

APOC4-APOC2 readthrough (HGNC Symbol)

Entrez gene summary

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

45445495 - 45452822

Ensembl

ENSG00000224916 (version 73.37)

Entrez gene

344

UniProt

neXtProt

Antibodypedia

APOC4-APOC2 antibodies
 

PROTEIN VIEW

? »
 
 
 
APOC4-APOC2-201
 
APOC4-APOC2-202
 
APOC4-APOC2-203
 
APOC4-APOC2-204
 
APOC4-APOC2-205
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOC4-APOC2-201 ENSP00000252490
ENST00000252490
Q6P163
Show all »
Show » Show » 101 11.3 Yes 0
APOC4-APOC2-202 ENSP00000406381
ENST00000419266
K7EMC3
Show all »
Show » Show » 127 14.6 Yes 0
APOC4-APOC2-203 ENSP00000412935
ENST00000436871
K7EMC3
Show all »
Show » Show » 127 14.6 Yes 0
APOC4-APOC2-204 ENSP00000467185
ENST00000585685
K7EMC3
Show all »
Show » Show » 127 14.6 Yes 0
APOC4-APOC2-205 ENSP00000468139
ENST00000589057
K7ER74
Show all »
Show » Show » 178 20 Yes 1