DCAF8L1

GENERAL INFORMATION

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Gene name

DCAF8L1

Gene description

DDB1 and CUL4 associated factor 8-like 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein localization

Expression in cilia in seminiferous ducts, fallopian tube and respiratory epithelium.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA043787
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

DCAF8L1 (HGNC Symbol)

Synonyms

WDR42B

Description

DDB1 and CUL4 associated factor 8-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate the formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 1. However, the CDS of this intronless gene remains intact, it is conserved in other primate species, it is known to be transcribed, and it is therefore thought to encode a functional protein. [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

p21.3

Chromosome location (bp)

27977993 - 27981355

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000226372 (version 78.38)

Entrez gene

139425

UniProt

A6NGE4 (UniProt - Evidence at transcript level)

neXtProt

NX_A6NGE4

Antibodypedia

DCAF8L1 antibodies


PROTEIN BROWSER

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ENST00000441525
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCAF8L1-001 ENSP00000405222
ENST00000441525
A6NGE4
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