CASP16

GENERAL INFORMATION

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Gene name

CASP16

Gene description

Caspase 16, apoptosis-related cysteine peptidase (putative)

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (duodenum, small intestine, spleen)
GTEx:Group enriched (adrenal gland, liver, small intestine, spleen)

Protein evidence

Evidence at transcript level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in duodenum. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA062836
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (duodenum, small intestine, spleen)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (adrenal gland, liver, small intestine, spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CASP16

Synonyms

Description

Caspase 16, apoptosis-related cysteine peptidase (putative) (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

3144219 - 3149963

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000228146 (version 78.38)

Entrez gene

197350

UniProt

P0CB46 (UniProt - Uncertain)

neXtProt

NX_P0CB46

Antibodypedia

CASP16 antibodies


PROTEIN BROWSER

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ENST00000428155
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CASP16-001 ENSP00000400592
ENST00000428155
P0CB46
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