APOC2

GENE INFORMATION

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Gene name

APOC2

Synonyms

Description

apolipoprotein C-II (HGNC Symbol)

Entrez gene summary

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

45450460 - 45452822

Ensembl

ENSG00000234906 (version 73.37)

Entrez gene

344

UniProt

P02655 (UniProt - Evidence at protein level)

neXtProt

NX_P02655

Antibodypedia

APOC2 antibodies
 

PROTEIN VIEW

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APOC2-001
 
APOC2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOC2-001 ENSP00000466775
ENST00000590360
P02655
Show all »
Show » Show » 101 11.3 Yes 0
APOC2-002 ENSP00000465001
ENST00000585786
Q6P163
Show all »
Show » Show » 72 8.1 Yes 0