MRPS17

GENE INFORMATION

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Gene name

MRPS17 (HGNC Symbol)

Synonyms

HSPC011, MRP-S17, RPMS17

Description

mitochondrial ribosomal protein S17 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

56019512 - 56024192

Ensembl

ENSG00000239789 (version 73.37)

Entrez gene

51373

UniProt

Q9Y2R5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y2R5

Antibodypedia

MRPS17 antibodies
 

PROTEIN VIEW

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MRPS17-001
 
MRPS17-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS17-001 ENSP00000285298
ENST00000285298
Q9Y2R5
Show all »
Show » Show » 130 14.5 No 0
MRPS17-002 ENSP00000401349
ENST00000443449
E9PE17
Show all »
Show » 129 14.4 No 0