PISD

GENE INFORMATION

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Gene name

PISD (HGNC Symbol)

Synonyms

dJ858B16.2, PSDC

Description

phosphatidylserine decarboxylase (HGNC Symbol)

Entrez gene summary

Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]).[supplied by OMIM, Jul 2010]

Chromosome

22 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

32014477 - 32058418

Ensembl

ENSG00000241878 (version 73.37)

Entrez gene

23761

UniProt

Q9UG56 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UG56

Antibodypedia

PISD antibodies
 

PROTEIN VIEW

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 « 
 
PISD-001
 
PISD-004
 
PISD-006
 
PISD-007
 
PISD-009
 
PISD-010
 
PISD-012
 
PISD-014
 
PISD-017
 
PISD-201
 
PISD-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PISD-001 ENSP00000391739
ENST00000439502
Q9UG56
Show all »
Show » Show » 409 46.7 No 0
PISD-004 ENSP00000414395
ENST00000435900
Show » Show » 362 41.3 No 0
PISD-006 ENSP00000380637
ENST00000397500
B1AKM6
Show all »
Show » Show » 262 30.3 No 1
PISD-007 ENSP00000371586
ENST00000382151
Q9UG56
Show all »
Show » Show » 375 43 No 1
PISD-009 ENSP00000396002
ENST00000429683
B1AKN0
Show all »
Show » 73 8.5 No 1
PISD-010 ENSP00000401606
ENST00000431201
B1AKN0
Show all »
Show » 73 8.5 No 1
PISD-012 ENSP00000412169
ENST00000422020
B1AKM8
Show all »
Show » Show » 228 26.3 No 0
PISD-014 ENSP00000399818
ENST00000442379
B1AKM9
Show all »
Show » 81 9.4 No 1
PISD-017 ENSP00000396500
ENST00000437808
F8WCS6
Show all »
56 6 No 0
PISD-201 ENSP00000266095
ENST00000266095
Q9UG56
Show all »
Show » Show » 375 43 No 1
PISD-202 ENSP00000338695
ENST00000336566
Q9UG56
Show all »
Show » Show » 408 46.6 No 0