C2orf15

GENE INFORMATION

? »

Gene name

C2orf15 (HGNC Symbol)

Synonyms

MGC29762

Description

chromosome 2 open reading frame 15 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene. [provided by RefSeq, Mar 2011]

Chromosome

2 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

99757948 - 99939204

Ensembl

ENSG00000241962 (version 73.37)

Entrez gene

51263

UniProt

Q8WU43 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WU43

Antibodypedia

C2orf15 antibodies
 

PROTEIN VIEW

? »
 
 
 
C2orf15-001
 
C2orf15-002
 
C2orf15-004
 
C2orf15-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C2orf15-001 ENSP00000302202
ENST00000302513
Q8WU43
Show all »
125 13.7 No 0
C2orf15-002 ENSP00000386654
ENST00000409684
Q8WU43
Show all »
125 13.7 No 0
C2orf15-004 ENSP00000390891
ENST00000424491
Show » 191 21.8 No 0
C2orf15-201 ENSP00000420959
ENST00000512183
Show » 161 18.5 No 0