MRPL33

GENE INFORMATION

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Gene name

MRPL33 (HGNC Symbol)

Synonyms

C2orf1, RPL33L

Description

mitochondrial ribosomal protein L33 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p23.2

Chromosome location (bp)

27994584 - 28210954

Ensembl

ENSG00000243147 (version 73.37)

Entrez gene

9553

UniProt

O75394 (UniProt - Evidence at protein level)

neXtProt

NX_O75394

Antibodypedia

MRPL33 antibodies
 

PROTEIN VIEW

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MRPL33-001
 
MRPL33-002
 
MRPL33-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL33-001 ENSP00000296102
ENST00000296102
O75394
Show all »
Show » Show » 65 7.6 No 0
MRPL33-002 ENSP00000368988
ENST00000379666
O75394
Show all »
Show » Show » 54 6 No 0
MRPL33-006 ENSP00000407385
ENST00000448427
F8WF37
Show all »
Show » 69 8.2 No 0