IL10RB

GENE INFORMATION

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Gene name

IL10RB (HGNC Symbol)

Synonyms

CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2

Description

interleukin 10 receptor, beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q22.11

Chromosome location (bp)

34638663 - 34669539

Ensembl

ENSG00000243646 (version 73.37)

Entrez gene

3588

UniProt

Q08334 (UniProt - Evidence at protein level)

neXtProt

NX_Q08334

Antibodypedia

IL10RB antibodies
 

PROTEIN VIEW

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IL10RB-001
 
IL10RB-003
 
IL10RB-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL10RB-001 ENSP00000290200
ENST00000290200
Q08334
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Show » Show » 325 37 Yes 1
IL10RB-003 ENSP00000414682
ENST00000422891
F8WDX2
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Show » 71 7.9 Yes 0
IL10RB-004 ENSP00000397611
ENST00000451065
H7C0Z5
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Show » Show » 216 25.3 No 1