CEBPA

GENE INFORMATION

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Gene name

CEBPA (HGNC Symbol)

Synonyms

C/EBP-alpha, CEBP

Description

CCAAT/enhancer binding protein (C/EBP), alpha (HGNC Symbol)

Entrez gene summary

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.11

Chromosome location (bp)

33790840 - 33793470

Ensembl

ENSG00000245848 (version 73.37)

Entrez gene

1050

UniProt

P49715 (UniProt - Evidence at protein level)

neXtProt

NX_P49715

Antibodypedia

CEBPA antibodies
 

PROTEIN VIEW

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CEBPA-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEBPA-001 ENSP00000427514
ENST00000498907
P49715
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