INSL3

GENE INFORMATION

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Gene name

INSL3 (HGNC Symbol)

Synonyms

MGC119818, MGC119819, RLF, RLNL

Description

insulin-like 3 (Leydig cell) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Chromosome

19 (Chromosome progress)

Cytoband

p13.11

Chromosome location (bp)

17927321 - 17932383

Ensembl

ENSG00000248099 (version 73.37)

Entrez gene

3640

UniProt

P51460 (UniProt - Evidence at protein level)

neXtProt

NX_P51460

Antibodypedia

INSL3 antibodies
 

PROTEIN VIEW

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INSL3-001
 
INSL3-002
 
INSL3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

INSL3-001 ENSP00000321724
ENST00000317306
P51460
Show all »
Show » Show » 131 14.5 Yes 0
INSL3-002 ENSP00000369017
ENST00000379695
P51460
Show all »
Show » Show » 157 16.9 Yes 0
INSL3-003 ENSP00000469309
ENST00000598577
Show » Show » 71 7.6 Yes 0