CDK11B

GENE INFORMATION

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Gene name

CDK11B (HGNC Symbol)

Synonyms

CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58

Description

Cyclin-dependent kinase 11B (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Chromosome

1

Cytoband

p36.33

Chromosome location (bp)

1635227 - 1722818

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000248333 (version 78.38)

Entrez gene

984

UniProt

neXtProt

Antibodypedia

CDK11B antibodies
 

PROTEIN VIEW

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CDK11B-001
 
CDK11B-003
 
CDK11B-005
 
CDK11B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDK11B-001 ENSP00000463048
ENST00000341832
B7ZVY7
Show all »
Show » Show » 782 91.3 No 0
CDK11B-003 ENSP00000464036
ENST00000407249
Q6P5Y5
Show all »
Show » Show » 795 92.6 No 0
CDK11B-005 ENSP00000464016
ENST00000340677
A4VCI5
Show all »
Show » Show » 748 87.1 No 0
CDK11B-201 ENSP00000463200
ENST00000317673
A4VCI5
Show all »
Show » Show » 780 91 No 0