MRPS17

GENE INFORMATION

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Gene name

MRPS17

Synonyms

Description

28S ribosomal protein S17, mitochondrial; HCG1984214, isoform CRA_a (UniProtKB/TrEMBL)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

55954970 - 56022932

Ensembl

ENSG00000249773 (version 73.37)

Entrez gene

51373

UniProt

neXtProt

Antibodypedia

MRPS17 antibodies
 

PROTEIN VIEW

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MRPS17-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS17-001 ENSP00000390331
ENST00000426595
I3L0E3
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