GYPB

GENE INFORMATION

? »

Gene name

GYPB (HGNC Symbol)

Synonyms

CD235b, GPB, MNS, SS

Description

glycophorin B (MNS blood group) (HGNC Symbol)

Entrez gene summary

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q31.21

Chromosome location (bp)

144917257 - 145061844

Ensembl

ENSG00000250361 (version 73.37)

Entrez gene

2994

UniProt

P06028 (UniProt - Evidence at protein level)

neXtProt

NX_P06028

Antibodypedia

GYPB antibodies
 

PROTEIN VIEW

? »
 
 
 
GYPB-001
 
GYPB-002
 
GYPB-003
 
GYPB-006
 
GYPB-007
 
GYPB-008
 
GYPB-009
 
GYPB-010
 
GYPB-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GYPB-001 ENSP00000427690
ENST00000502664
P06028
Show all »
Show » Show » 91 9.8 Yes 1
GYPB-002 ENSP00000422726
ENST00000506679
D6RAD9
Show all »
42 4.6 Yes 0
GYPB-003 ENSP00000424025
ENST00000506516
D6RBP2
Show all »
19 2.1 Yes 0
GYPB-006 ENSP00000425244
ENST00000513128
B8Q174
Show all »
Show » Show » 58 6.4 Yes 1
GYPB-007 ENSP00000423025
ENST00000511198
D6RA87
Show all »
45 4.9 Yes 0
GYPB-008 ENSP00000394200
ENST00000429670
E7ERJ5
Show all »
Show » 62 6.7 Yes 0
GYPB-009 ENSP00000423055
ENST00000505583
D6RA87
Show all »
45 4.9 Yes 0
GYPB-010 ENSP00000421974
ENST00000504951
D6RA87
Show all »
45 4.9 Yes 0
GYPB-201 ENSP00000283126
ENST00000283126
P06028
Show all »
Show » Show » 91 9.8 Yes 1