PRKDC

GENE INFORMATION

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Gene name

PRKDC (HGNC Symbol)

Synonyms

DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7

Description

protein kinase, DNA-activated, catalytic polypeptide (HGNC Symbol)

Entrez gene summary

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]

Chromosome

8 (Chromosome progress)

Cytoband

q11.21

Chromosome location (bp)

48685669 - 48872743

Ensembl

ENSG00000253729 (version 73.37)

Entrez gene

5591

UniProt

P78527 (UniProt - Evidence at protein level)

neXtProt

NX_P78527

Antibodypedia

PRKDC antibodies
 

PROTEIN VIEW

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PRKDC-005
 
PRKDC-010
 
PRKDC-201
 
PRKDC-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRKDC-005 ENSP00000441157
ENST00000540819
F5GX40
Show all »
Show » 70 8 No 0
PRKDC-010 ENSP00000442177
ENST00000536429
Show » 90 10.1 No 0
PRKDC-201 ENSP00000313420
ENST00000314191
P78527
Show all »
Show » Show » 4127 469 No 0
PRKDC-202 ENSP00000345182
ENST00000338368
E7EUY0
Show all »
Show » Show » 4096 465.4 No 0