CUX1

GENERAL INFORMATION

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Gene name

CUX1

Gene description

Cut-like homeobox 1

Protein class

Cancer-related genes
Predicted intracellular proteins
Predicted membrane proteins
Transcription factors

Predicted localization

Intracellular,Membrane

Number of transcripts

12
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear or granular cytoplasmic expression. The annotation is based on antibodies recognizing different splice variants.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA003277 , HPA003317
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CUX1 (HGNC Symbol)

Synonyms

CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6

Description

Cut-like homeobox 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

101815904 - 102283957

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000257923 (version 78.38)

Entrez gene

1523

UniProt

P39880 (UniProt - Evidence at protein level), Q13948 (UniProt - Evidence at protein level)

neXtProt

NX_P39880, NX_Q13948

Antibodypedia

CUX1 antibodies


PROTEIN BROWSER

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ENST00000292535
 
ENST00000292538
 
ENST00000360264
 
ENST00000393824
 
ENST00000425244
 
ENST00000437600
 
ENST00000546411
 
ENST00000547394
 
ENST00000549414
 
ENST00000550008
 
ENST00000556210
 
ENST00000622516
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CUX1-001 ENSP00000292538
ENST00000292538
Q13948
Show all »
Show » Show » 678 77.5 No 1
CUX1-002 ENSP00000449371
ENST00000547394
Q13948
Show all »
Show » Show » 662 75.6 No 1
CUX1-003 ENSP00000484760
ENST00000622516
Q13948
Show all »
Show » Show » 676 77.2 No 1
CUX1-004 ENSP00000292535
ENST00000292535
P39880
Show all »
Show » Show » 1505 164.2 No 0
CUX1-005 ENSP00000353401
ENST00000360264
P39880
Show all »
Show » Show » 1516 165.7 No 0
CUX1-006 ENSP00000446630
ENST00000549414
P39880
Show all »
Show » Show » 1483 161.6 No 0
CUX1-007 ENSP00000447373
ENST00000550008
P39880
Show all »
Show » Show » 1449 157.9 No 0
CUX1-008 ENSP00000450125
ENST00000546411
P39880
Show all »
Show » Show » 1403 153.4 No 0
CUX1-009 ENSP00000451558
ENST00000556210
P39880
Show all »
Show » Show » 1347 147.1 No 0
CUX1-016 ENSP00000377410
ENST00000393824
Q13948
Show all »
Show » Show » 639 72.8 No 1
CUX1-018 ENSP00000409745
ENST00000425244
P39880
Show all »
Show » Show » 632 72 No 1
CUX1-201 ENSP00000414091
ENST00000437600
Q13948
Show all »
Show » Show » 678 77.5 No 1