MRPL46

GENE INFORMATION

? »

Gene name

MRPL46 (HGNC Symbol)

Synonyms

C15orf4, LIECG2, P2ECSL

Description

mitochondrial ribosomal protein L46 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

89002707 - 89010650

Ensembl

ENSG00000259494 (version 73.37)

Entrez gene

26589

UniProt

Q9H2W6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H2W6

Antibodypedia

MRPL46 antibodies
 

PROTEIN VIEW

? »
 
 
 
MRPL46-001
 
MRPL46-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL46-001 ENSP00000312311
ENST00000312475
Q9H2W6
Show all »
Show » Show » 279 31.7 No 0
MRPL46-004 ENSP00000453881
ENST00000560703
H0YN64
Show all »
86 9.4 No 0