The Human Protein Atlas

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THE HUMAN PROTEIN ATLAS

WELCOME INTRODUCTION ASSAYS & ANNOTATION DATA QUALITY & SCORING DISCLAIMER RELEASE HISTORY DATA USAGE POLICY ANTIBODY AVAILABILITY DOWNLOADABLE DATA

TISSUE DICTIONARY

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ANTIBODY SUBMISSION

ANTIBODY SUBMISSION CONDITIONS

ANDNOT

Field

All —Gene nameProtein classChromosomeExternal id —Subcellular location (IF)Organ expression (IH)Tissue expression (IH)Cancer expression (IH)Cell expression (IH) —IH validationIF validationWB validationPA validation —With antibodiesWith annotated expression (IH)With annotated expression (IF)

Term

Gene name

Class

KinasesCD markersBlood group antigen proteinsTransportersRibosomal proteinsPeptidasesCandidate cancer biomarkersG-protein coupled receptorsPlasma proteinsCandidate cardiovascular disease genesTranscription factorsEnzymesSH2-domain containing proteinsSH3-domain containing proteinsMutated genes in cancerVoltage-gated ion channelsPotential transmembrane proteinsMapped to UniProt SWISS-PROT

Subclass

Chromosome

12345678910111213141516171819202122HG79_PATCHMTUnmappedXY

External id

Location

Nucleus Nucleoli Nucleus but not nucleoli Nuclear membrane Plasma membrane Cytoplasm Mitochondria Endoplasmic reticulum Golgi apparatus Vesicles Cytoskeleton Cytoskeleton (Actin filaments) Cytoskeleton (Intermediate filaments) Cytoskeleton (Microtubules) Centrosome Extracellular matrix Focal Adhesions Cell Junctions Aggresome

Organ

AnyCentral nervous system (Brain)Blood and immune system (Hematopoietic)Liver and pancreasDigestive tract (GI-tract)Respiratory system (Lung)Cardiovascular system (Heart and blood vessels)Breast and female reproductive system (Female tissues)PlacentaMale reproductive system (Male tissues)Urinary tract (Kidney and bladder)Skin and soft tissuesEndocrine glands

Fraction

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tissues

0%5%10%15%20%25%30%35%40%45%50%55%60%65%70%75%80%85%90%95%100%

Expression

Negative Weak Moderate Strong

Tissue

AnyAdrenal glandAppendixBone marrowBreastBronchusCerebellumCerebral cortexCervix, uterineColonDuodenumEpididymisEsophagusFallopian tubeGall bladderHeart muscleHippocampusKidneyLateral ventricleLiverLungLymph nodeNasopharynxOral mucosaOvaryPancreasParathyroid glandPlacentaProstateRectumSalivary glandSeminal vesicleSkeletal muscleSkinSmall intestineSmooth muscleSpleenStomach, lowerStomach, upperTestisThyroid glandTonsilUrinary bladderUterus, post-menopauseUterus, pre-menopauseVaginaVulva/anal skin

Cell type

Expression

Negative Weak Moderate Strong

Tissue

AnyBreast cancerCervical cancerColorectal cancerEndometrial cancerHead and neck cancerLiver cancerLung cancerMalignant carcinoidMalignant gliomaMalignant lymphomaMalignant melanomaOvarian cancerPancreatic cancerProstate cancerRenal cancerSkin cancerStomach cancerTestis cancerThyroid cancerUrothelial cancer

Fraction

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patients

0%5%10%15%20%25%30%35%40%45%50%55%60%65%70%75%80%85%90%95%100%

Expression

Negative Weak Moderate Strong

Cell	Expression Negative Weak Moderate Strong

Validation

Supportive Uncertain Non-supportive

Validation

Supportive Uncertain Non-supportive

Validation

Supportive Uncertain Non-supportive

Validation

Supportive Uncertain Non-supportive

Antibodies

YesNo

Annotated expression

YesNo

Annotated expression

YesNo

TISSUE DICTIONARY

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.