The human protein atlas blog

World Malaria Day April 25

Malaria Tissue Atlas

SLC4A1 in kidney.

This blog post is in honor of World Malaria Day

When infected mosquitos bite people they transmit parasites that causes malaria. Symptoms of malaria include fever and flu-like illness, and if left untreated the illness will cause anemia (loss of red blood cells) and eventually death.

According to WHO, malaria caused 429 000 deaths in 2015, and 70% of the deaths are children under the age of 5. Luckily, mortality rates are falling, and since 2010 the mortality has dropped with almost 1/3. Early diagnosis and treatment of malaria reduces deaths and prevents transmission. There are antimalaria drugs available, but currently, there is no availabe malaria vaccine...Read more

Cell Image of the Month - It is Taco Friday!

Cell Atlas Image of the week Mitochondria

Antibody HPA021643 in U-2 OS recognizing TACO1 in mitochondria.

Today we highlight another part of Swedish or Scandinavian (food) culture - "Taco Fredag" or "Taco Friday". Doesn't sound Swedish to you? But staying in on a Friday night and having tacos with your family and/or friends is a thing here, and a big thing as it happens, with supermarkets having entire sections dedicated to this tradition.

So what other image to look at in this week's edition of the Human Protein Atlas blog than the one representing TACO1. TACO1 acts as a translational activator for the mitochondrial encoded cytochrome c oxidase 1, which is a component of complex IV of the mitochondrial respiratory complex...Read more

On epitope mapping and therapeutic antibodies

Antibody Antibody Microarray Epitope mapping

Johan Rockberg

Today we meet yet another researcher within the Human Protein Atlas project, Johan Rockberg, Associate Professor in antibody technology and directed evolution at KTH - Royal Institute of Technology in Stockholm, Sweden. He is the group leader for the epitope mapping and therapeutic antibodies group within the Human Protein Atlas.

– I have a M. Sc in chemical engineering from KTH and University of Sydney and joined the Human Protein Atlas Project in 2003, right in the beginning. Since I took courses in computational and information science in parallel with chemical engineering it was natural to pursue a career in bioinformatics...Read more

AACR Annual Meeting 2017

Conference Pathology Atlas

Cecilia Lindskog and Borbala Katona in the booth

A team from the Human Protein Atlas is attending the AACR Annual Meeting 2017 in Washington DC right now. This year, the meeting covers topics on research propelling cancer prevention and cures, and the Human Protein Atlas is represented by a booth where our team gives a personalized go-through of the Atlas to everyone who is interested in our open access resource. In addition, a demo version of a new Pathology Atlas can also be previewed in our booth. It will contain information on the prognostic genes and proteins for clinical outcome of the major cancer types in humans...Read more