The human protein atlas blog


The Human Cell Atlas selected as one of 10 emerging technologies to make a change to society

2017-06-27
Cell Atlas Human Protein Atlas Technologies

This week, Scientific American announced ten emerging technologies with innovations that are on the verge of changing society. One of the technologies selected was the Human Cell Atlas, which aims to integrate research exploring the building-blocks of human cells using new emerging technologies. The list of ten emerging technologies was compiled in a collaboration between Scientific American and the World Economic Forum's Expert Network with suggestions from members of the Expert Network, the forum's Global Future Councils and Scientific American's board of advisers...Read more


Image of the Week - GPR17 and oligodendrocytes

2017-06-22
GPR17 Mouse Brain Protein Atlas oligodendrocytes

Staining of GPR17 (green) with DAPI (blue) in oligodendrocytes from thalamic areas of the mouse brain.

In this week's image of the week we look at G protein-coupled receptor 17 (GPR17), a member of the G protein-coupled receptor (GPCR) family, whose members serve as important regulators of oligodendrocyte development.

Oligodendrocytes are the cells that mainly provide support and electrically insulate axons in the brain by forming the myelin sheath. During development, these cells progress from oligodendrocyte precursor cells to myelinating mature oligodendrocytes. GPR17, in particular is an oligodendroglial maturation inhibitor since its stimulation arrests mouse oligodendrocytes at a less differentiated stage...Read more


CYTO2017 Image analysis challenge

2017-06-15
Cell Atlas CYTO2017 Image analysis image challenge

Winner and organizers of the CYTO2017 challenge. From left to right: Carolina Wählby, Devin Sullivan, Peng Qui, Emma Lundberg

We would like to thank all participants of the CYTO2017 Image analysis challenge co-organized by the Cell Atlas team. And congratulate the winner, Dr. Peng Qiu from Georgia Tech, who at the time of the challenge closing had the top solution for both Challenge 2 and Challenge 3.

Though submissions this year were high-quality, and showcased the multitude of approaches to such a challenge, there is still large room for improvements in the results and some sub-challenges remain entirely unsolved. Therefore, we have decided to keep the challenge open for another year! Improvements in downloads and scoring schemes will be made.

So stay tuned for updates...Read more


Conference - keynote lecture at CYTO2017 in Boston

2017-06-12
Cell Atlas CYTO2017 Human Protein Atlas Single cell analysis

Emma Lundberg Director of the Human Cell Atlas, will present a keynote lecture on June 14th, entitled ”The Cell Atlas: A subcellular map of the human proteome” on the 32ndCongress of the International Society for Advancement of Cytometry in Boston, USA.

On this occassion, the CYTO Congress together with the Human Protein Atlas have organized a challenge for analysis of the images from the Cell Atlas, culminating in presentation of results in the final conference session, where participants will present their analytical methods and findings...Read more


Image of the Week

2017-06-12

In this week’s post, we will highlight proteins specifically expressed in a tissue with extensive plasticity - the female mammary glands. The evolutionary origin of mammary and milk gland-like structures is believed to date all the way back to 300 million years ago, and glandular secretory apocrine-like units in the skin of synapsids, an ancestor to mammals.

The mammary gland develops from the epidermis and is mainly composed of branched columnar and cuboidal epithelial cells that form distinct lobes...Read more