THE HUMAN PROTEIN ATLAS BLOG

Autoantibody targets in narcolepsy

2016-05-31   |   0 Comments
Autoantibody Autoimmunity Proteomics Vaccine

Anna Häggmark

A new study by researchers within the Human Protein Atlas project was just published in Autoimmunity .

The researchers analyzed the presence of autoantibodies in patients with vaccine-associated narcolepsy. In an initial screening, IgG reactivity to approximately 10000 protein fragments was investigated, revealing a large heterogeneity in which autoantibodies that are present in different individuals.

Anna Häggmark is the first author of the paper...Read more


Investigating autoantibody reactivity in lungs

2016-01-12   |   0 Comments
Autoantibody Autoimmunity Microarray Sarcoidosis

A study of autoimmune targets in sarcoidosis revealed higher reactivity in patients compared to controls for four proteins in both bronchoalveolar lavage (BAL) and serum.

Proteomic Profiling Reveals Autoimmune Targets in Sarcoidosis

Sarcoidosis is an inflammatory lung disease with unknown cause. Previous research has shown that sarcoidosis patients have generally higher levels of antibodies compared to healthy controls but so far the role and protein targets of these antibodies are not well understood.

In this study we used protein microarrays to investigate autoantibody targets in bronchoalveolar lavage (BAL) fluid in the search for autoantigens associated to disease...Read more