The human protein atlas blog
Let‘s have a look at the protein TPX2, a microtubule nucleation factor that translocates from the nucleus - where it resides during interphase - to the mitotic spindle during mitosis.
The mitotic spindle forms when chromosomes are ready to segregate during cell division and not surprisingly this protein is also found in this specific compartment of the cell! TPX2 is required for the correct formation of the kinetochores that is crucial for the attachment of microtubules, enabling the sister chromatids to be pulled apart...Read more
This week, Scientific American announced ten emerging technologies with innovations that are on the verge of changing society. One of the technologies selected was the Human Cell Atlas, which aims to integrate research exploring the building-blocks of human cells using new emerging technologies. The list of ten emerging technologies was compiled in a collaboration between Scientific American and the World Economic Forum's Expert Network with suggestions from members of the Expert Network, the forum's Global Future Councils and Scientific American's board of advisers...Read more
We would like to thank all participants of the CYTO2017 Image analysis challenge co-organized by the Cell Atlas team. And congratulate the winner, Dr. Peng Qiu from Georgia Tech, who at the time of the challenge closing had the top solution for both Challenge 2 and Challenge 3.
Though submissions this year were high-quality, and showcased the multitude of approaches to such a challenge, there is still large room for improvements in the results and some sub-challenges remain entirely unsolved. Therefore, we have decided to keep the challenge open for another year! Improvements in downloads and scoring schemes will be made.
So stay tuned for updates...Read more
Emma Lundberg Director of the Human Cell Atlas, will present a keynote lecture on June 14th, entitled ”The Cell Atlas: A subcellular map of the human proteome” on the 32ndCongress of the International Society for Advancement of Cytometry in Boston, USA.
On this occassion, the CYTO Congress together with the Human Protein Atlas have organized a challenge for analysis of the images from the Cell Atlas, culminating in presentation of results in the final conference session, where participants will present their analytical methods and findings...Read more
The Cell Atlas database was just recently released with data on more than 12.000 proteins and mapping to 30 organelles. Today, the scientific findings are published in Science in "A subcellular map of the humanproteome".
The cell is a complex entity that carries out multiple functions. In order to do this, the different parts of the cells are organized in structures, called organelles. By investigating the organelles and its proteome, and to understand how the proteins vary over time and space we can truly begin to understand human biology on a detailed level...Read more