THE HUMAN PROTEIN ATLAS BLOG

Investigating autoantibody reactivity in lungs

2016-01-12   |   0 Comments
Autoantibody Autoimmunity Microarray Sarcoidosis

A study of autoimmune targets in sarcoidosis revealed higher reactivity in patients compared to controls for four proteins in both bronchoalveolar lavage (BAL) and serum.

Proteomic Profiling Reveals Autoimmune Targets in Sarcoidosis

Sarcoidosis is an inflammatory lung disease with unknown cause. Previous research has shown that sarcoidosis patients have generally higher levels of antibodies compared to healthy controls but so far the role and protein targets of these antibodies are not well understood.

In this study we used protein microarrays to investigate autoantibody targets in bronchoalveolar lavage (BAL) fluid in the search for autoantigens associated to disease...Read more