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Staining of plasma membrane in human cell line A-549 (HPA005785)
Scale bar represents 10µm

Plasma membrane

The plasma membrane encloses the cell content and enables a selective transport of molecules in and out of the cell, either through passive diffusion or through active uptake. It also takes part in signal conduction through receptors embedded in the membrane, which consists of a lipid bilayer.

Immunofluorescent staining

Immunofluorescent staining of the plasma membrane can appear differently. Sometimes the staining only appear as a rim around the cell, sometimes membrane protrusions extending from the plasma membrane are clearly visible and sometimes it may appear as a uniform and very flat staining across the entire cell (since the plasma membrane beneath the cell is stained). It can be difficult to distinguish plasma membrane staining from cytoplasmic staining when the images show the plasma membrane underneath the cell.

Examples IF

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Examples IH

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