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Dictionary > Protein expression > CHGA

Detail 1
Normal adrenal gland showing expression of CHGA in medullar compartment of the adrenal gland.

Chromogranin A (CHGA) - Marker for neuroendocrine cells

The CHGA gene belongs to the granin-family of neuroendocrine secretory proteins. The gene encodes for Chromogranin A, which is found in neurons and endocrine cells. Chromogranin A inhibits insulin-release from the pancreas, but is also a precursor of several bioactive peptides that regulate the neuroendocrine function of the secreting cell itself, or cells nearby. In a clinical setting CHGA is used to indicate neuroendocrine tumors including carcinoids.

Show CHGA in the protein atlas.

Normal tissue - Protein expression

Adrenal gland
Parathyroid gland

Cancer tissue - Protein expression