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Dictionary > Protein expression > TP53

Detail 1
Breast cancer (ductal carcinoma, grade 1) showing essentially negative staining for the p53 (TP53) in tumor cells and in normal glands of the breast.

Tumor protein p53 (TP53) - The anti-cancer watchdog

The p53 protein is encoded by the TP53 gene and has important functions to protect against cancer and p53 expression is involved in control of cell cycle progression, DNA-repair and apoptosis. Mutations in the TP63 gene will cause severe reduction in tumor suppression activity, and this is reflected by studies showing that more than half of all tumors contain display mutations or silencing of TP53.

Show TP53 in the protein atlas.

Cancer tissue - Protein expression

Breast cancer 1, ductal carcinoma
Breast cancer 2, ductal carcinoma
Colorectal cancer 1, adenocarcinoma
Colorectal cancer 2, adenocarcinoma
Lung cancer
Prostate cancer 1, adenocarcinoma
Prostate cancer 2, adenocarcinoma
Testis cancer
Thyroid cancer