Cervical cancer is the third most common cancer type in women worldwide. Screening programs have contributed to decreased mortality, however, cervical cancer remains a major cause of cancer-related death among women in countries with limited access to screening. By using a systems level approach to analyze the cervical cancer proteome based on clinical metadata and genome-wide transcriptomics data, 724 genes were found to be associated with prognostic outcome...Read more
In an article in "Onkologi i Sverige" (Swedish) Prof. Fredrik Pontén has written an article on the history, background and development of the Human Protein Atlas project. General strategies and historic milestones are described as well as an update of the current status of the three main parts of the current version of the Human Protein Atlas; the Normal Tissue Atlas, the Cell Atlas and the recent Pathology Atlas.
Read the full article (in Swedish)...Read more
Mammographic breast density is one of the strongest risk factors for breast cancer, but molecular understanding of how breast density relates to cancer risk is less complete. Studies of proteins in blood plasma, possibly associated with mammographic density, are well-suited as these allow large-scale analyses and might shed light on the association between breast cancer and breast density...Read more