This month we turn the spotlight to retinol binding protein 2 (gene: RBP2), which plays an important role in the uptake of vitamin A in the intestines. Now that winter has arrived, we increasingly need good night vision and a strong immune system - two physiological processes that we have vitamin A to thank for...Read more

The defense mechanism of our adaptive immune system relies on the antigen-recognition abilities of two molecules: T cell receptors (TCRs), attached to the surface of T cells, and immunoglobins (Igs), anchored to and secreted by B cells. These molecules are equipped with pockets that bind with remarkable selectivity to a specific antigen. Our bodies maintain an estimated 1014 specificities for Igs and a whopping 1018 for TCRs. Considering our entire genome harbors approximately 105 genes, how is this diversity achieved?..Read more

In the online on-demand symposium Advances in Proteomics & Metabolomics 2023 hosted by Technology Networks, leading scientists have been brought together to highlight the latest advancements in translational proteomics and metabolomics...Read more

In this movie neurologist Per Svenningsson at Karolinska Institute explains how 3D visualization of the brain using light-sheet microscopy can be used to better understand Parkinson´s disease...Read more

In a publication in Clinical Proteomics a novel orthogonal strategy based on affinity proteomics and mass spectrometry was used for analytical validation of biomarkers in longitudinally collected serum samples from Duchenne muscular dystrophy (DMD) patients...Read more