Upcoming events


XII EuPA Congress

June 16, 2018 - June 20, 2018

On Tuesday June 19, at 16:45, Jochen Schwenk will present "An update on the Human Plasma Proteome" at the XII EuPA Congress - Translating genomes into biological functions - that will take place in Santiago de Compostela (Spain) on June 16-20, 2018. Programme

Past events


11th International Congress on Autoimmunity

May 16, 2018 - May 19, 2018

HPA presence at Autoimmunity Congress 2018, 16-20 May

Nine researchers from KTH in Stockholm will present the work of autoimmunity profiling within the Human Protein Atlas at the 11th international congress on Autoimmunity in Lisbon, Portugal, 16-20 May 2018.
Congress site

With ten submitted abstracts, eight were selected for oral presentations in numerous sessions of the congress, meaning that the Human Protein Atlas will span the schedule of the congress with a significant coverage.

The detailed schedule for HPA oral and poster presentations is found below:

May 17

15:30 - 15:40
Jennie Olofsson: Autoantibody Profiling of Amyotrophic Lateral Sclerosis Plasma
Parallel session: Neuronal Autoimmune Diseases

16:15 - 16:20
Cecilia Hellstrõm: Longitudinal Profiling of Autoantibody Repertoires in 99 Healthy Individuals
Short oral discussion 6 - Prediction, Monitoring and Prevention, Precision (Personalized) Medicine in Autoimmunity (Station 2)

08:00 - 18:30
Elisa Pin: Increased Autoantibody Reactivity in Saliva of Young Athletes after Subconcussion
Poster session: Central Nervous System and Autoimmunity: Eye, Smell and Psychiatry

May 18

11:20 - 11:30
Anna Mânberg: Profiling the IGG Repertoire in CSF from Patients with Frontotemporal Dementia
Parallel session: Autoimmunity and Psychiatric Diseases

11:30 - 11:40
David Just: Towards Molecular Insights into Psychiatric Disorders Using Affinity Proteomics
Parallel session: Autoimmunity and Psychiatric Diseases

May 19

11:20 - 11:30
Ronald Sjõberg: Comprehensive Auto-Antibody Investigation Of Psychiatric Disorder On High-Density Protein Microarray Platforms
Parallel session: Multiplex Diagnostic Techniques and Chips of Autoimmune Diseases

14:40 - 15:00
Lucia Lourido: Circulating Autoantibodies for Prediction of Response to Infliximab in Rheumatoid Arthritis
Parallel session: Theraputical Response with Antibiological Drugs Antibodies

16:05 - 16:10
Elisa Pin: Profiling the Autoantibody Repertoire in Vasculitis
Short oral discussion 18 - Vasculitides, Hormones and Autoimmunity (Station 2)

17:30 - 17:40
Peter Nilsson: Replication and Validation of the Autoantigen Anoctamin 2 Association with Increased Risk for Multiple Sclerosis
Parallel session: Multiple Sclerosis (Ms); What Is New?

08:00 - 18:30
Eni Andersson: Autoantibody Profiling Using High-Density Protein Microarrays
Poster session: Precision (Personalized) Medicine In Autoimmunity

Wellness profiling and the Human Protein Atlas

May 9, 2018, 11:45am CEST, 11:45am CEST

On May 9 Linn Fagerberg will present "Wellness profiling and the Human Protein Atlas" at the SciLifeLab lunch seminar: Cutting-edge technologies in Precision Cancer Medicine at Clarion Hotel Sign. Programme

Cell Culture Engineering XVI

May 6, 2018 - May 11, 2018

Cell Culture Engineering conferences are held bi-annually. On May 6th Prof. Mathias Uhlen will open the conference with a keynote lecture on "The Human Protein Atlas - Implications for Human Biology, Drug Development and Precision Medicine". Final programme

Webinar Science

April 11, 2018, 6:00pm CEST, 6:00pm CEST

WEBINAR | Addressing the reproducibility crisis: Validating antibodies for life science research

Speakers: Mathias Uhlen and Cecilia Williams

Antibodies are invaluable tools in the life sciences. There are several challenges that must be overcome to validate the specificity and reproducibility of antibody reagents, as emphasized by many publications, including a recent proposal from the International Working Group for Antibody Validation (IWGAV). There are many examples of antibodies with off-target binding leading to erroneous conclusions, some of which will be discussed during this webcast, demonstrating the importance of application-specific validation. Five alternative strategies for enhanced validation of antibodies will be described based on genetic validation, recombinant expression, independent antibodies, orthogonal validation, and capture mass spectrometry validation. Approaches based on these five strategies have been used for streamlined, enhanced validation of more than 10,000 antibodies from more than 30 providers, targeting over 7,000 human proteins as part of the Human Protein Atlas program. The results show a path forward for validating antibodies in an application-specific manner suitable for both providers and users.

During the webinar, viewers will learn about:

  • The generation and validation of data used in the Human Protein Atlas
  • Problems related to the cross-reactivity of antibodies and the challenges they create for the interpretation of results
  • Enhanced validation of antibodies using five application-specific strategies.
Speakers will answer your questions during the live broadcast!

Registration

Course in antibody based technologies at Scilifelab April

April 10, 2018 - April 11, 2018

Short info: 

Where: Air and Fire, Scilifelab Solna

When: April 10-11, 2018

Credits: 1 hp

The course will focus on antibody based technologies and describe the possibilities of using these technologies within the facilities at SciLifeLab. Lectures will cover both theoretical and more practical aspects of the different technologies, including the following:

  • Immunohistochemistry
  • Immunofluorescence
  • Tissue fluorescence profiling
  • Protein array technologies and suspension bead technologies
  • Mass cytometry and flow cytometry
  • Immuno capture/immuno precipitation in combination with mass spectrometry
  • Proximity ligation assays

Apart from general aspects of the technologies, the course will include project presentations to demonstrate the benefits and possibilities of the technologies in different contexts. Last but not least validation strategies of antibodies for different applications will be covered, as this is of outmost importance for adequate output data.

Please read more and apply through the following link:

Antibody based technologies

Bioprocessing Summit Europe

March 21, 2018 - March 22, 2018

On Thursday March 22nd, Prof Sophia Hober will present "A Protein A-Derived Domain with Calcium-Dependent Affinity for Use in Antibody Purification" at the Cambridge Healthtech Institute's Inaugural "Advances in Recovery and Purification" Programme.

US HUPO

March 11, 2018 - March 14, 2018

The title of 2018 year's US HUPO conference is "Technology accelerating discovery". Dr. Emma Lundberg will hold the closing plenary session, titled "Spatiotemporal proteome organization of the human cell" on March 14. Programme

Proteomics in Cell Biology and Disease Mechanisms

February 28, 2018 - March 2, 2018

The Wellcome Genome Campus organizes the conference Proteomics in Cell Biology and Disease Mechanisms where Dr. Emma Lundberg will present "Dissecting the spatiotemporal subcellular distribution of the human proteome". Her talk is scheduled on March 2. Draft programme

The Human Protein Atlas - implications for human biology and precision medicine

January 25, 2018

Dr Cecilia Lindskog will present the Pathology Atlas, the association of all human genes with patient survival, and other recent milestones and high-profile findings in the Human Protein Atlas project at the 8th Symposium on Pharmaceutical Profiling in Drug Discovery and Development. Venue: The Humanities Theater, English Park Campus, Uppsala University.

Programme

Frontiers in Biology

January 24, 2018

Upcoming presentation by Emma Lundberg at Stanford on "Spatial proteomics and the single cell".

Protein A-Based purification of antibodies

January 8, 2018

Prof. Sophia Hober will present the latest advances regarding engineering of protein A, for Ca-mediated purification of antibodies. Her talk is scheduled on January 9, during one of the largest annual events focusing on protein science, the PepTalk conference. "Optimization of an IgG-Binding, Protein A-Based Purification Matrix".

High-Throughput Protein Production within the Swedish Human Protein Atlas

January 8, 2018 - January 12, 2018

Development of the Human Protein Atlas, protein production pipeline will be highlighted in the upcoming PepTalk conference in a talk given by PhD Hanna Tegel on January 11th. "High-Throughput Protein Production within the Swedish Human Protein Atlas Project".

Presentation at Biogenouest network meeting

December 7, 2017

Dr. Cecilia Lindskog Bergström, Director of the Tissue Atlas, will present "The Human Protein Atlas - implications for human biology and precision medicine", at the annual meeting of the Biogenouest network in Nantes, France, this year with the theme "Antibodies used in proteomics".

ASCB/EMBO meeting starts on the 2 of December

December 2, 2017 - December 6, 2017

First joint ASCB/EMBO meeting is organized in Philadelphia in December. Invited talks highlight the value of sharing scientific results through publicly available databases and international co-operations to increase our understanding of cell biology. The Cell Atlas team presents protein atlas, in booth #218.

News article

Wellness Profiling program presented at the EMBL organised symposium - From Single to Multi-omics

November 10, 2017

On Nov 13, Dr Linn Fagerberg will present a talk at the EMBO|EMBL symposia "From Single to Multi-omics: Applications and Challenges in Data Integration" in Heidelberg, Germany.

The HPA at the Image-based Cell Atlas Meeting

October 6, 2017 - November 30, 2017

World-leading scientists summoned to discuss how to map the human cell and promote research on human health and diseases. The meeting emphasised the importance of image-based assays to accomplish such an endeavor.

News article