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Image of the week - CDC42 and actin filaments

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This week HPA image of the week, I've decided to highlight two of my favorite things, the cell cycle and actin filaments!

The protein labeled in Fig 1. is an image of Cell division cycle 42 effector protein (Rho GTPase binding) 4 (CDC42EP4). In addition to being quite a mouthful, this protein resides in the cytoplasm and is associated with the actin filaments. In this image, CDC42EP4 is seen in U-2 OS human osteosarcoma cells.

As the name suggests, the CDC42EP4 is a protein associated with CDC42, which helps regulate the transition from G1 to S (in which DNA is replicated), and is essential for proper cell cycle progression (Yasuda S et al. 2006)...Read more


Upcoming Events


Precision Health: Molecular Basis, Technology and Digital Health

November 13, 2019 - November 16, 2019

Emma Lundberg will give a talk on "Spatial proteomics and cell biology" at the EMBO Workshop, Precision Health: Molecular Basis, Technology and Digital Health, held at EMBL Heidelberg, Germany.