News ArticlesCell Image of the Month - Let there be SUNSUN2 (Sad1 and UNC84 domain containing 2), found in the nuclear membrane of cells, is an essential protein for many cellular processes. SUN plays a large role in the organization of multi-nucleated muscle cells, and dysregulation of SUN can cause muscular dystrophy among other diseases...Read more Autophagosomes in the cellAutophagosomes play a crucial role in recycling, by degrading cellular components and providing building blocks for renewal och cell components. Last year, we published a post about autophagy, which was the subject of the 2016 Nobel Prize in Physiology and Medicine. We show, for the first time, images of HPA antibodies that co-localize with the autophagosomes. These membrane bound vesicles are involved in degradation of cellular constituents through a process called autophagy. The protein detected is localized to the autophagosomes (green) in SH-SY5Y cells, a human neuroblastoma cell line from neural tissue...Read more NFIL3 a protein that follows the winter seasonDiurnal cycle influence biological processes in all organisms, on a molecular level, through regulators of the circadian clock. The Nuclear factor interleukin-3-regulated protein is a component of the circadian clock in humans that also fluctuates with the seasons. The Human Protein Atlas team has stained in A-431 cells NFIL3 (green) in nuclear bodies with DNA (blue) and microtubules (red)...Read more Proteomic analysis of cell cycle progression reveal mitotic substagesDistinct mitotic substages have been identified during cell cycle progression. The different subphases are characterised by variation in protein abundance and degree of phosphorylation...Read more The HPA at the Image-based Cell Atlas Meeting
The importance of mapping the human cell has become recognized as one of the key challenges in modern biology. Image-based assays offer a data-rich medium of studying cells and their proteins in situ. As such, several large-scale initiatives for studying cellular biology using image-based assays have been founded in recent years...Read more Upcoming EventsSingle Cells: Technology to BiologyFebruary 24, 2019 - February 26, 2019Dr. Emma Lundberg, will give a presentation on "Dissecting spatiotemporal variations of the human proteome" at the Cell Symposium "Single Cells: Technology to Biology" held at the A* STAR Genome Institute of Singapore. She will present on Monday February 25, at 16:15.Programme 9th Alpbach Workshop on Affinity ProteomicsMarch 11, 2019 - March 13, 2019The 9th Alpbach workshop will take place in the state-of-the-art Congress Centre in Alpbach/Austria. |