News ArticlesThe in situ expression of missing proteins in spermatogenesisSpermatogenesis is the process where sperm are made, and it involves thousands of genes and proteins that are activated and repressed. The function of a large proportion of these genes and proteins remains unknown and testis harbors many "missing proteins" (MPs)...Read more GATA-1, KLF-1 and IKZF1 - Transcription Factors in HematopoiesisThroughout life, blood cells are continuously formed in the bone marrow, a process known as hematopoiesis. Hematopoiesis relies on several different mediators, and defects in this system may cause severe pathological conditions...Read more The Fertilizing Fallopian TubesThe fallopian tube mucosal layer is a simple columnar epithelium composed of secretory and ciliated epithelial cells, in order to provide the necessary environment for fertilization of the egg cell...Read more Integration of transcriptomics and antibody-based proteomics for exploration of proteinsApproximately 11% of the human proteins are defined as missing proteins. These proteins lack experimental data on the protein level. In an investigation led by Sjöstedt et al, an integrated omics approach was applied to explore and identify missing proteins...Read more TH, DBH and PNMT play pivotal roles in catecholamine production in the adrenal medullaLocated on top of the kidneys like two tiny caps, the adrenal glands play a fundamental role in the endocrine system. We have previously described the human adrenal gland proteome and now it is time to shed light on proteins specific for the medullary compartment of the adrenal gland. These proteins are essential for the synthesis of two major stress coping hormones - adrenaline and noradrenaline...Read more |