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From primary to malignant - what changes?

Malignant transformation_Frida.jpg

Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model

From primary to malignant - what changes? Bridging transcriptomics and proteomics to reveal the molecular changes during malignant transformation in a four-step cancer cell line model

In order to find out more about the changes that occur when a primary cell is transformed into an aggressive cancer cell, integration of biological information has proven to be successful. By bridging transcriptomics and antibody based proteomics data we showed how the major changes during malignant transformation could be scrutinized...Read more


Upcoming Events


Cell Culture Engineering XVI

May 6, 2018 - May 11, 2018

Cell Culture Engineering conferences are held bi-annually. On May 6th Prof. Mathias Uhlen will open the conference with a keynote lecture on "The Human Protein Atlas - Implications for Human Biology, Drug Development and Precision Medicine". Preliminary programme