Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 214.6;liver: 375.4" "Group enriched" "Detected in some" 5 "Hepatocytes: 7.1;Mesothelial cells: 13.6" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.7;Myeloma: 3.9" "Liver - Hepatocytes" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" "Complement pathway" NA NA 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 458.6" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 654.1" "Cancer enriched" "Detected in many" 19 "liver cancer: 83.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.5" "Adipose subcutaneous - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 265000000000 1100000000 "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Hepatocytes - Metabolism" "Golgi apparatus" "HPA000925: , HPA051620: AB_2681554" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (2.07e-3)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-3)" "unprognostic (9.49e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (6.39e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (8.25e-2)" C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 1860.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 321.7;Hepatocytes: 852.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 434.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.6" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.6" "Cancer enhanced" "Detected in some" "liver cancer: 7.4;lung cancer: 3.9" "Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA000926, HPA001578" Enhanced "Secreted to blood" "Complement pathway" NA NA 30800000000 28000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA000926: AB_1078355, HPA001578: AB_1078354" "unprognostic (3.85e-4)" "unprognostic (9.07e-2)" "unprognostic (2.06e-1)" "prognostic favorable (6.37e-5)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.24e-4)" "unprognostic (3.64e-2)" "unprognostic (1.94e-1)" "unprognostic (5.90e-4)" "unprognostic (4.47e-2)" "unprognostic (2.58e-1)" "unprognostic (5.51e-7)" "unprognostic (9.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-1)" LRRC4B "DKFZp761A179, HSM, LRIG4" ENSG00000131409 "Leucine rich repeat containing 4B" Q9NT99 19 50516892-50568435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.0;cervix: 40.0;pituitary gland: 31.1" "Cell type enhanced" "Detected in some" "Astrocytes: 33.1;Bipolar cells: 15.9;Excitatory neurons: 31.0;Horizontal cells: 27.1;Inhibitory neurons: 36.8;Oligodendrocyte precursor cells: 27.8;Oligodendrocytes: 45.5" "Group enriched" "Detected in many" 9 "glioma: 36.5;testis cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 14.6;Neuroblastoma: 25.7;Rhabdoid: 21.3;skin cancer: 6.7" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058986 Uncertain NA NA 2700000 "Cluster 33: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA058986: AB_2683871" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-2)" "unprognostic (4.48e-2)" "unprognostic (3.56e-1)" "unprognostic (5.39e-4)" "unprognostic (2.70e-2)" "unprognostic (1.11e-1)" "unprognostic (5.28e-2)" "unprognostic (4.61e-3)" "unprognostic (1.11e-3)" "unprognostic (3.41e-1)" "unprognostic (3.15e-5)" "unprognostic (4.29e-2)" "unprognostic (2.61e-1)" "unprognostic (3.64e-1)" "unprognostic (2.17e-1)" C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 112.2;liver: 328.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 6.8;Mesothelial cells: 8.5" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 8.8;Myeloma: 6.7" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" "Complement pathway" NA NA 342000000 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.8;lymphoid tissue: 26.5" "Cell type enhanced" "Detected in some" "B-cells: 40.6;Erythroid cells: 17.0;Hofbauer cells: 16.9;Kupffer cells: 96.2;Macrophages: 42.4;monocytes: 23.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 53.8;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.8" "Group enriched" "Detected in some" 9 "Leukemia: 3.6;lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophil_2, Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 20: Non-specific - DNA binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 39.4;pituitary gland: 14.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 562.4;Horizontal cells: 163.0;Inhibitory neurons: 608.2;Oligodendrocyte precursor cells: 249.0;Spermatocytes: 105.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 10.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" RP1L1 DCDC4B ENSG00000183638 "RP1 like 1" Q8IWN7 8 10606349-10712187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "retina: 42.8" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 124.0;Rod photoreceptor cells: 65.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024686, HPA024744" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA024686: AB_2671650, HPA024744: AB_2671668" "unprognostic (3.27e-1)" "unprognostic (9.97e-2)" "unprognostic (1.24e-1)" "unprognostic (6.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-5)" "unprognostic (3.57e-1)" "unprognostic (5.22e-2)" "unprognostic (2.08e-4)" "unprognostic (8.52e-2)" "unprognostic (5.77e-2)" "unprognostic (6.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.82e-1)" XAF1 "BIRC4BP, HSXIAPAF1, XIAPAF1" ENSG00000132530 "XIAP associated factor 1" Q6GPH4 17 6755447-6775647 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 156.4;Endothelial cells: 73.4;Microglial cells: 98.4;Ovarian stromal cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057302 Approved Supported Nucleoplasm,Mitochondria Yes NA "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 14 "Nucleoplasm, Mitochondria" "HPA057302: AB_2683405" "unprognostic (6.28e-2)" "unprognostic (1.71e-1)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.09e-3)" "unprognostic (4.89e-2)" "unprognostic (1.39e-1)" "unprognostic (8.08e-3)" "unprognostic (3.34e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.73e-7)" "unprognostic (2.33e-1)" "unprognostic (1.74e-2)" "unprognostic (2.31e-1)" "unprognostic (6.15e-3)" CR1L ENSG00000197721 "Complement C3b/C4b receptor 1 like" Q2VPA4 1 207645113-207738416 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "bone marrow: 1.5" "Cell type enriched" "Detected in some" 8 "Erythroid cells: 82.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049348 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "HPA049348: AB_2680723" "unprognostic (2.35e-2)" "unprognostic (8.27e-2)" "unprognostic (1.99e-1)" "unprognostic (8.89e-2)" "unprognostic (1.31e-2)" "unprognostic (5.50e-2)" "unprognostic (2.01e-1)" "unprognostic (7.45e-2)" "unprognostic (5.27e-2)" "unprognostic (8.21e-3)" "unprognostic (7.94e-2)" "unprognostic (3.02e-1)" "unprognostic (6.33e-2)" "unprognostic (2.02e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (9.68e-2)" CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752037-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 301.2;eosinophil: 387.4;neutrophil: 404.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 404.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 74: Neutrophils - Degranulation" 2 "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109731008-109802150 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 952.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 454.5;Muller glia cells: 114.1;Proximal tubular cells: 195.1" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" "Complement pathway" NA NA 12000000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" MASP2 "MAP-2, Map19, MASP1P1, sMAP" ENSG00000009724 "MBL associated serine protease 2" O00187 1 11022009-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "liver: 464.7" "Cell type enriched" "Detected in some" 47 "Hepatocytes: 634.2" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 340000000 820000000 "Cluster 83: Liver - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 4 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 137.3;liver: 274.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 261.3;Mesothelial cells: 85.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Region enriched" "Detected in all" 34 "choroid plexus: 214.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 46.7" "Breast - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" "Blood coagulation" NA NA 22500000000 5000000000 "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 4 "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)"