Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 82.4;lymphoid tissue: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 43.2;Hofbauer cells: 56.7;Kupffer cells: 84.5;Macrophages: 49.9;monocytes: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 316.6" "Group enriched" "Detected in many" 4 "dendritic cells: 162.8;granulocytes: 316.6;monocytes: 151.9" "Cancer enriched" "Detected in many" 5 "Leukemia: 52.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 4 "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646777-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.6" "Group enriched" "Detected in many" 5 "Erythroid cells: 163.7;Oocytes: 214.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 48000 "Cluster 11: T-cells - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 1 Nucleoplasm "CAB016546: AB_630417" "unprognostic (1.15e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "unprognostic (2.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (9.91e-2)" "unprognostic (8.24e-3)" "unprognostic (4.89e-2)" "unprognostic (5.83e-3)" "unprognostic (6.78e-2)" "unprognostic (9.03e-2)" "unprognostic (9.35e-2)" "unprognostic (1.09e-1)" HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 101.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 19000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 5 Cytosol "Vesicles, Centrosome" "CAB005865: AB_304116, HPA070398: , HPA071444: AB_2686396" "unprognostic (3.07e-2)" "unprognostic (6.36e-2)" "unprognostic (5.41e-2)" "unprognostic (8.05e-2)" "unprognostic (9.24e-2)" "unprognostic (1.43e-1)" "unprognostic (3.71e-3)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (1.52e-1)" "unprognostic (6.20e-3)" "unprognostic (7.23e-2)" "unprognostic (4.28e-3)" "unprognostic (2.44e-2)" "unprognostic (2.62e-1)" "unprognostic (9.45e-2)" "unprognostic (2.14e-2)" NUBP2 "CFD1, CIAO6" ENSG00000095906 "NUBP iron-sulfur cluster assembly factor 2, cytosolic" Q9Y5Y2 16 1782932-1789186 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041704 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 10 "Nucleoplasm, Cytosol" "HPA041704: AB_10804006" "unprognostic (1.94e-1)" "unprognostic (5.73e-3)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.02e-2)" "unprognostic (8.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.42e-1)" "unprognostic (1.53e-1)" "unprognostic (8.64e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.63e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.83e-2)" ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1466.0;Late spermatids: 948.7;Proximal tubular cells: 1197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 39: Non-specific - Basic cellular processes" 16 "Mitochondria, Cytosol" "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" NUBP1 "CIAO5, NBP1, NBP35" ENSG00000103274 "NUBP iron-sulfur cluster assembly factor 1, cytosolic" P53384 16 10743786-10769351 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041656, HPA041799" Enhanced Supported Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 14: Langerhans cells - Innate immune response" Cytosol "HPA041656: AB_10960278, HPA041799: AB_10960692" "unprognostic (2.51e-2)" "prognostic favorable (2.81e-5)" "unprognostic (4.01e-3)" "unprognostic (1.66e-3)" "unprognostic (2.81e-1)" "unprognostic (7.04e-2)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (8.28e-2)" "unprognostic (5.08e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "prognostic favorable (7.61e-8)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (8.23e-2)" "unprognostic (1.69e-2)" BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 166.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 482.5;Proximal tubular cells: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Non-specific - Basic cellular processes" 7 "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747841-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 196.6;Early spermatids: 148.4;Excitatory neurons: 257.1;granulocytes: 117.7;Inhibitory neurons: 300.7;Late spermatids: 194.8;Microglial cells: 217.4;Oligodendrocyte precursor cells: 266.5;Oligodendrocytes: 201.0;Oocytes: 247.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 22: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 69: Neurons - Neuronal signaling" 3 Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favorable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" LYRM7 "C5orf31, FLJ20796, MZM1L" ENSG00000186687 "LYR motif containing 7" Q5U5X0 5 131170944-131205428 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 32.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 116.0;Early spermatids: 159.9;Late spermatids: 210.4;Spermatocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050053 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA050053: AB_2680999" "unprognostic (1.88e-2)" "unprognostic (2.89e-1)" "unprognostic (3.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.90e-2)" "unprognostic (1.02e-1)" "unprognostic (9.03e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "unprognostic (1.50e-2)" "unprognostic (3.03e-1)" "prognostic favorable (9.84e-6)" "unprognostic (6.61e-2)" "unprognostic (2.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.20e-1)" NDUFS3 CI-30 ENSG00000213619 "NADH:ubiquinone oxidoreductase core subunit S3" O75489 11 47565336-47584562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 282.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004484, CAB034894" Enhanced Supported "Nuclear bodies,Mitochondria" NA NA 14000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 7 Mitochondria "Nuclear bodies" "CAB034894: AB_2151118, HPA004484: AB_1079464" "unprognostic (2.18e-1)" "unprognostic (7.42e-3)" "unprognostic (1.75e-1)" "unprognostic (5.01e-2)" "unprognostic (7.51e-2)" "unprognostic (3.13e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.41e-2)" "unprognostic (6.75e-3)" "unprognostic (7.73e-2)" "prognostic favorable (2.61e-6)" "unprognostic (2.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (3.17e-3)" NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "NUBP iron-sulfur cluster assembly factor, mitochondrial" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 64.7;Inhibitory neurons: 71.7;Oligodendrocyte precursor cells: 82.5;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Neurons - Neuronal signaling" 1 Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" ACTA1 "ACTA, NEM3" ENSG00000143632 "Actin alpha 1, skeletal muscle" P68133 1 229430365-229434104 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 127668.4" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 15973.8" "Group enriched" "Detected in many" 18 "head and neck cancer: 133.1;prostate cancer: 34.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "breast cancer: 3.0;Sarcoma: 2.8" "Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000045, HPA041264, HPA041271" Enhanced NA NA 2800000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 6 "CAB000045: AB_2242301, HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.59e-2)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (3.07e-4)" "unprognostic (5.75e-3)" "unprognostic (3.84e-3)" "unprognostic (1.86e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.64e-3)" "unprognostic (2.50e-1)" "unprognostic (1.56e-3)" "unprognostic (9.40e-4)" "unprognostic (2.61e-1)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108223044-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 270.6;Oligodendrocytes: 202.6;Rod photoreceptor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 19 Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" ATN1 "B37, D12S755E, DRPLA" ENSG00000111676 "Atrophin 1" P54259 12 6924463-6942321 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031619 Enhanced Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 37: Glandular & Luminal cells - Unknown function" 9 Nucleoplasm "HPA031619: AB_10601667" "unprognostic (3.86e-3)" "unprognostic (2.07e-1)" "unprognostic (1.80e-3)" "unprognostic (5.82e-2)" "unprognostic (1.37e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (7.20e-4)" "unprognostic (1.44e-1)" "unprognostic (6.90e-2)" "unprognostic (8.42e-3)" "unprognostic (1.86e-2)" "unprognostic (3.19e-1)" "unprognostic (7.43e-2)" "unprognostic (5.46e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-1)" "unprognostic (7.35e-2)" BBC3 "JFY1, PUMA" ENSG00000105327 "BCL2 binding component 3" "Q96PG8, Q9BXH1" 19 47220822-47232766 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 100.6;Secretory cells: 157.9;Suprabasal keratinocytes: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 4.6;neutrophil: 3.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB007752, HPA070403" Approved Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 37: Glandular & Luminal cells - Unknown function" 12 Cytosol "CAB007752: AB_562336, HPA070403: " "unprognostic (4.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.31e-4)" "unprognostic (2.95e-2)" "unprognostic (4.74e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (1.93e-1)" "unprognostic (8.38e-3)" "unprognostic (7.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.66e-2)" "unprognostic (4.66e-3)" "unprognostic (5.06e-2)" "unprognostic (3.57e-1)" "prognostic favorable (2.62e-5)" CBX7 ENSG00000100307 "Chromobox 7" O95931 22 39120167-39152680 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Cardiomyocytes: 64.9;Rod photoreceptor cells: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011574, HPA048677, HPA056480" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" 9 Nucleoplasm Cytosol "CAB011574: AB_726005, HPA048677: AB_2680490, HPA056480: AB_2683146" "prognostic favorable (6.18e-4)" "prognostic favorable (3.63e-4)" "prognostic unfavorable (3.73e-4)" "unprognostic (9.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.48e-3)" "unprognostic (4.76e-3)" "unprognostic (1.45e-2)" "unprognostic (3.86e-2)" "unprognostic (1.11e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.03e-3)" "prognostic favorable (2.45e-5)" "unprognostic (3.90e-1)" "unprognostic (1.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.63e-2)" CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 112.0;Syncytiotrophoblasts: 107.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA050137: AB_2681029, HPA059843: AB_2684140" "unprognostic (3.94e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (2.92e-1)" "unprognostic (5.08e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.12e-1)" "unprognostic (8.50e-3)" "unprognostic (2.08e-2)" "unprognostic (1.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (8.75e-2)" "unprognostic (2.31e-1)" "unprognostic (2.71e-2)" "unprognostic (5.25e-2)" CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" 8 "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" CGAS "C6orf150, h-cGAS, MB21D1" ENSG00000164430 "Cyclic GMP-AMP synthase" Q8N884 6 73413515-73452297 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.8" "Cell type enhanced" "Detected in many" "dendritic cells: 32.3;Macrophages: 23.7;monocytes: 28.6;Plasma cells: 25.3;T-cells: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031700, HPA031701, HPA031702" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Cytosol" "HPA031700: AB_10601693, HPA031701: , HPA031702: AB_2673999" "unprognostic (2.49e-1)" "unprognostic (2.36e-1)" "unprognostic (4.61e-2)" "unprognostic (4.95e-2)" "unprognostic (2.49e-2)" "unprognostic (1.81e-1)" "unprognostic (4.84e-3)" "unprognostic (1.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.25e-2)" "unprognostic (2.20e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.27e-7)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-1)" COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 147.5;Proximal tubular cells: 157.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "HPA057768: AB_2683521" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (1.67e-3)" "unprognostic (2.61e-2)" "unprognostic (7.11e-2)" "unprognostic (4.69e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.32e-3)" "unprognostic (3.71e-3)" "unprognostic (8.00e-3)" "unprognostic (3.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.93e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.00e-5)" COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.0;Late spermatids: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 21: Early spermatids - Spermatogenesis" 5 "HPA051371: AB_2681459" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.75e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.45e-3)" "unprognostic (2.90e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.19e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.8" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 3: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 61: Plasma cells - Immunoglobulins & histones" 5 "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" DMP1 ENSG00000152592 "Dentin matrix acidic phosphoprotein 1" Q13316 4 87650280-87664361 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Rhabdoid: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037465 Approved "Secreted to extracellular matrix" Other NA NA 64000 "Cluster 3: Rhabdoid - Membrane components" "Cluster 18: Early spermatids - Unknown function" "HPA037465: AB_10672492" "unprognostic (6.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (1.80e-1)" "unprognostic (4.96e-3)" "unprognostic (7.73e-2)" "unprognostic (3.88e-1)" "unprognostic (1.11e-1)" "unprognostic (1.35e-2)" "unprognostic (8.50e-9)" "unprognostic (5.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (1.74e-3)" GBA1 "GBA, GLUC" ENSG00000177628 "Glucosylceramidase beta 1" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 15.3;Schwann cells: 13.4;Syncytiotrophoblasts: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" Enzyme NA NA 470000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 206.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Spermatocytes: 1.6;Spermatogonia: 2.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 2.1" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" HSF1 HSTF1 ENSG00000185122 "Heat shock transcription factor 1" Q00613 8 144291591-144314720 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Host-virus interaction, mRNA processing, mRNA transport, Stress response, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004239, HPA008888" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 25 Nucleoplasm Cytosol "CAB004239: AB_627753, HPA008888: AB_1079088" "unprognostic (7.08e-2)" "unprognostic (1.89e-2)" "unprognostic (6.07e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (1.55e-1)" "unprognostic (5.63e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.69e-3)" "unprognostic (1.05e-1)" "unprognostic (4.35e-2)" "unprognostic (1.40e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-2)" "unprognostic (2.23e-1)" "unprognostic (2.13e-1)" "unprognostic (1.12e-1)" IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" Receptor NA NA 310000 "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 113.8" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 65.5" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040692, HPA040948" Supported "Secreted to blood" "Cell adhesion" NA NA 14700000000 26000000000 "Cluster 83: Liver - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 71.7;granulocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 77.1" "Group enriched" "Detected in all" 5 "B-cells: 77.1;granulocytes: 31.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 139.2" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 38500 110000 "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 3 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 49.4;lymphoid tissue: 97.0" "Cell type enhanced" "Detected in many" "B-cells: 109.9;dendritic cells: 73.2;Kupffer cells: 62.4;Microglial cells: 173.6;monocytes: 60.3;NK-cells: 143.4;T-cells: 66.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 43.8;lymphoma: 38.7" "Adipose subcutaneous - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016300, HPA070455" Enhanced Supported Cytosol No No 4400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 9 Cytosol "CAB016300: AB_628250, HPA070455: AB_2686267" "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 296.7;breast: 87.3" "Group enriched" "Detected in some" 52 "Extravillous trophoblasts: 142.2;Syncytiotrophoblasts: 376.0" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "testis cancer: 2.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010490, HPA068565" Approved Approved "Vesicles,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 17000000 19000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Vesicles, Plasma membrane" "CAB010490: AB_2296951, HPA068565: " "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 50.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 767.5;monocytes: 185.4;Oligodendrocyte precursor cells: 241.0;Skeletal myocytes: 246.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.3" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.3;lymphoma: 3.2;skin cancer: 3.4" "Breast - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Alveolar cells - Lung function" 108 Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 60.1;Spermatogonia: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 2 Nucleoplasm Cytosol "HPA045141: AB_2679230, HPA066433: " "unprognostic (6.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (5.78e-2)" "prognostic unfavorable (9.30e-8)" "unprognostic (5.21e-2)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (3.47e-1)" MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 131.9;Oligodendrocytes: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" MS4A2 "APY, FCER1B, IGER" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.2" "Cell type enriched" "Detected in some" 29 "granulocytes: 1187.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 873 "basophil: 275.8" "Lineage enriched" "Detected in single" 1528 "granulocytes: 275.8" "Cancer enriched" "Detected in single" 14 "Leukemia: 1.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Kidney - T-cells, Lung - Mast cells, Skin - Mast cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 20.9" HPA059967 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" 1 "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" MSH2 "COCA1, HNPCC, HNPCC1, MSH-2" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 83.3" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867, CAB080131" Supported Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 52: Non-specific - Cell proliferation" 8 Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , CAB080131: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" MSH6 "GTBP, MSH-6" ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 92.7" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 52: Non-specific - Cell proliferation" 3 Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 682.7;Proximal tubular cells: 443.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 17 Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 237.9;urinary bladder: 174.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 133.4;Breast glandular cells: 99.1;Endometrial stromal cells: 101.4;Endothelial cells: 108.9;Fibroblasts: 93.6;granulocytes: 135.2;Lymphatic endothelial cells: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 246.4" "Kidney - Endothelial cells, Prostate - Urothelial cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" Enzyme NA NA 9900000 110000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8862534 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "basophil: 207.1" "Lineage enriched" "Detected in all" 12 "granulocytes: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040852, HPA063649" Approved Approved Nucleoplasm,Cytosol NA NA 21000 "Cluster 46: Basophils - Proteolysis" "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm Cytosol "HPA040852: AB_10794069, HPA063649: AB_2685074" "unprognostic (8.62e-3)" "unprognostic (8.00e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-2)" "unprognostic (6.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (5.14e-3)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (6.89e-2)" "unprognostic (5.02e-2)" PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700188-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "Nucleoplasm, Golgi apparatus" "HPA005809: AB_1079673" "unprognostic (2.22e-1)" "unprognostic (3.28e-1)" "unprognostic (5.34e-2)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (2.72e-3)" "unprognostic (1.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-2)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (9.63e-3)" "unprognostic (3.81e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.85e-3)" RAD54B RDH54 ENSG00000197275 "RAD54 homolog B" Q9Y620 8 94371960-94475115 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 6.8" "Cell type enhanced" "Detected in many" "Astrocytes: 27.6;Cone photoreceptor cells: 17.0;Excitatory neurons: 44.3;Inhibitory neurons: 18.2;Oligodendrocyte precursor cells: 37.3;Oligodendrocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 10 "B-cells: 1.0;T-cells: 1.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA007087 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Non-specific - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 3 "Nucleoplasm, Cytosol" "HPA007087: AB_1856040" "unprognostic (1.68e-3)" "unprognostic (2.51e-1)" "unprognostic (2.31e-2)" "unprognostic (8.84e-3)" "unprognostic (4.15e-2)" "unprognostic (1.44e-1)" "unprognostic (5.56e-8)" "unprognostic (1.96e-2)" "unprognostic (1.77e-2)" "unprognostic (5.39e-2)" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (2.04e-12)" "unprognostic (5.86e-2)" "unprognostic (5.23e-1)" "unprognostic (9.08e-2)" "unprognostic (6.68e-5)" RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0;testis: 15.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 6.7;Extravillous trophoblasts: 9.2;Glandular and luminal cells: 5.1;Plasma cells: 5.1;Spermatocytes: 12.6;Spermatogonia: 5.7;Undifferentiated cells: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 52: Non-specific - Cell proliferation" 2 Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.4;liver: 13.3;stomach 1: 10.2;urinary bladder: 15.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.8;Alveolar cells type 2: 9.9;Cholangiocytes: 15.3;Collecting duct cells: 7.8;Gastric mucus-secreting cells: 10.0;Glandular and luminal cells: 8.3;Hepatocytes: 17.7;Intestinal goblet cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "Developmental protein" NA NA 5500000 "Cluster 83: Liver - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" SIRT6 ENSG00000077463 "Sirtuin 6" Q8N6T7 19 4174109-4182566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Acyltransferase, Chromatin regulator, Developmental protein, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049729, HPA071776" Supported Supported Nucleoplasm,Vesicles No No "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 4 Nucleoplasm Vesicles "HPA049729: AB_2680865, HPA071776: AB_2686445" "unprognostic (4.58e-1)" "unprognostic (3.41e-3)" "unprognostic (1.36e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.93e-3)" "unprognostic (8.32e-2)" "unprognostic (1.86e-1)" "unprognostic (6.13e-2)" "unprognostic (7.27e-3)" "unprognostic (4.42e-2)" "unprognostic (5.84e-2)" "prognostic favorable (9.13e-4)" "unprognostic (5.17e-2)" "unprognostic (1.63e-1)" "prognostic favorable (2.58e-4)" SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 44.8;breast: 27.5;placenta: 23.3" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 66.3;Syncytiotrophoblasts: 166.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 10.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 9 Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.9;Proximal enterocytes: 44.8" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063062 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.1;Late spermatids: 176.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Photoreceptor cells - Visual perception" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 47.8;salivary gland: 94.7" "Group enriched" "Detected in many" 4 "Mucus glandular cells: 372.9;Salivary duct cells: 790.2" "Cancer enhanced" "Detected in many" "testis cancer: 21.8" "Region enriched" "Detected in all" 8 "choroid plexus: 39.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" "Nucleoli fibrillar center" Mitochondria "HPA029708: AB_10602479" "unprognostic (8.85e-3)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.25e-2)" "unprognostic (2.72e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "prognostic favorable (7.72e-6)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (6.67e-3)" "unprognostic (2.01e-1)" TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 689 "thyroid gland: 9062.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.9;Proximal tubular cells: 3.7;Salivary duct cells: 8.7" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Group enriched" "Detected in some" 4 "amygdala: 5.8;cerebral cortex: 3.8;choroid plexus: 3.1;hippocampal formation: 3.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 9 "thyroid cancer: 16.6" "Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in many" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" Hormone NA NA 1600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" 8 "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 157 Nucleoplasm "Vesicles, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 76.9" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Basal squamous epithelial cells: 2.9;Excitatory neurons: 2.2;Gastric mucus-secreting cells: 2.4;Microglial cells: 5.4;Oligodendrocytes: 5.5;Plasma cells: 3.2;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 49: Non-specific - Transcription" Cytosol "HPA035437: AB_10672092, HPA046721: AB_2732531" ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral protein, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 50000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)"