Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 75.8;Extravillous trophoblasts: 137.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" Vesicles "Plasma membrane" "HPA020856: AB_1845320" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (3.64e-1)" "unprognostic (3.68e-2)" "unprognostic (6.80e-3)" "unprognostic (3.87e-3)" "unprognostic (6.12e-2)" "unprognostic (8.90e-2)" "unprognostic (1.60e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (8.75e-5)" "unprognostic (8.67e-2)" "unprognostic (3.62e-2)" "unprognostic (2.37e-1)" "unprognostic (2.56e-1)" WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 40.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.5;Alveolar cells type 2: 8.7;Basal prostatic cells: 1.7;Collecting duct cells: 3.9;Ionocytes: 1.5;Suprabasal keratinocytes: 2.4" "Group enriched" "Detected in many" 7 "head and neck cancer: 18.9;melanoma: 14.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 3.5" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA 86000 "Cluster 13: Skin - Cornification" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 5 "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-3)" "unprognostic (1.72e-2)" "unprognostic (8.70e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (4.49e-2)" "unprognostic (3.91e-1)" "unprognostic (5.50e-3)" MAGEA12 "CT1.12, MAGE12" ENSG00000213401 "MAGE family member A12" P43365 X 152733757-152737669 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.7" "Group enriched" "Detected in some" 5 "Spermatocytes: 10.5;Spermatogonia: 20.2" "Cancer enhanced" "Detected in many" "melanoma: 10.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Spermatogonia - Spermatogenesis" 17 "unprognostic (3.47e-2)" "unprognostic (4.54e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.82e-1)" "unprognostic (3.25e-1)" "unprognostic (1.60e-3)" "unprognostic (8.57e-4)" "unprognostic (4.61e-2)" "unprognostic (1.78e-1)" "unprognostic (4.06e-2)" IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129429607-129520510 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.8" "Cell type enhanced" "Detected in all" "Early spermatids: 80.8;Late spermatids: 67.8;Spermatocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041815 Uncertain Uncertain Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 31: Spermatocytes - Spermatogenesis" 10 Cytosol "HPA041815: AB_10804118" "unprognostic (7.16e-2)" "unprognostic (3.71e-3)" "unprognostic (3.67e-1)" "unprognostic (7.61e-3)" "unprognostic (5.29e-2)" "unprognostic (5.33e-3)" "unprognostic (4.68e-2)" "unprognostic (1.82e-1)" "unprognostic (7.90e-2)" "unprognostic (3.30e-1)" "unprognostic (1.67e-2)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" "unprognostic (7.67e-2)" "unprognostic (5.33e-1)" "unprognostic (9.91e-2)" "unprognostic (4.20e-3)" MIS12 "hMIS12, KNTC2AP, MGC2488, MTW1" ENSG00000167842 "MIS12 kinetochore complex component" Q9H081 17 5486285-5490814 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 124.6;Late spermatids: 227.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044482 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 12 "HPA044482: AB_10963834" "unprognostic (3.86e-2)" "unprognostic (4.85e-2)" "unprognostic (1.36e-1)" "unprognostic (4.22e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (4.68e-2)" "unprognostic (2.34e-3)" "unprognostic (3.41e-2)" "prognostic favorable (8.00e-4)" "unprognostic (4.13e-3)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (3.65e-2)" NBPF12 "COAS1, KIAA1245" ENSG00000268043 "NBPF member 12" Q5TAG4 1 146938324-146996202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 56.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.48e-2)" "unprognostic (3.97e-1)" "unprognostic (1.74e-1)" "unprognostic (8.96e-3)" "unprognostic (4.57e-2)" "unprognostic (5.00e-3)" "unprognostic (2.03e-2)" "unprognostic (5.76e-3)" "unprognostic (4.57e-2)" "unprognostic (2.90e-1)" "prognostic favorable (9.01e-7)" "unprognostic (2.23e-1)" "unprognostic (1.69e-3)" "unprognostic (2.96e-2)" "unprognostic (2.86e-1)" "unprognostic (2.08e-1)" "prognostic favorable (2.47e-5)" C12orf40 FLJ40126 ENSG00000180116 "Chromosome 12 open reading frame 40" Q86WS4 12 39626167-39908300 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 8.6" "Cell type enhanced" "Detected in some" "Early spermatids: 13.3;Late spermatids: 4.7;Oocytes: 27.2;Spermatocytes: 30.3;Spermatogonia: 6.0" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA039032 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Spermatocytes - Spermatogenesis" 4 "Golgi apparatus" Cytosol "HPA039032: AB_2676316" "unprognostic (1.75e-1)" "unprognostic (2.76e-6)" "unprognostic (3.45e-1)" "unprognostic (1.96e-1)" PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.9;Fibroblasts: 3.5;Lymphatic endothelial cells: 7.4;Mesothelial cells: 3.9;Skeletal myocytes: 10.7" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 5.8;skin cancer: 5.7" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 34: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" C12orf43 "Custos, FLJ12448" ENSG00000157895 "Chromosome 12 open reading frame 43" Q96C57 12 121000486-121016502 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046148, HPA061739" Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoli "Golgi apparatus" "HPA046148: AB_10965169, HPA061739: AB_2684597" "unprognostic (1.51e-1)" "unprognostic (5.75e-2)" "unprognostic (3.44e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (6.44e-4)" "unprognostic (3.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.95e-1)" "unprognostic (2.45e-3)" "unprognostic (9.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702126-169706360 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 120.6;Late spermatids: 273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" Other NA NA 620000 "Cluster 7: Non-specific - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" "HPA039626: AB_10673361" "unprognostic (2.98e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.43e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (9.52e-5)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-3)" MVB12B "C9orf28, FAM125B, FLJ00001" ENSG00000196814 "Multivesicular body subunit 12B" Q9H7P6 9 126326829-126507041 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 112.7" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 470.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043683, HPA049383" Approved "Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 51: Oligodendrocytes - Unknown function" 1 "Golgi apparatus, Vesicles" "HPA043683: AB_2678616, HPA049383: AB_2680737" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (6.82e-2)" "unprognostic (9.59e-3)" "unprognostic (4.77e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (4.45e-3)" "unprognostic (4.33e-1)" "unprognostic (1.05e-1)" "prognostic favorable (7.89e-4)" "unprognostic (2.82e-1)" "unprognostic (1.66e-3)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (5.79e-2)" "unprognostic (1.12e-3)" PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 8.9;Bipolar cells: 10.7;Horizontal cells: 8.2;Mesothelial cells: 5.0;Mucus glandular cells: 7.1;Secretory cells: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA035812: AB_2674796" "unprognostic (3.95e-2)" "unprognostic (7.74e-2)" "unprognostic (7.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-2)" "unprognostic (2.24e-2)" "unprognostic (2.08e-2)" "unprognostic (4.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-4)" "unprognostic (3.18e-4)" "unprognostic (1.11e-1)" "unprognostic (3.21e-3)" "unprognostic (6.97e-2)" PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Bipolar cells: 4.3;Endometrial stromal cells: 2.5;Fibroblasts: 2.6;Peritubular cells: 2.0;Skeletal myocytes: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Early spermatids" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.0" "Cell type enhanced" "Detected in all" "Early spermatids: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 105.6" "Cell type enhanced" "Detected in many" "dendritic cells: 975.8;Distal tubular cells: 1281.6;Ductal cells: 546.5;Extravillous trophoblasts: 1448.2;Pancreatic endocrine cells: 708.1;Proximal tubular cells: 852.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 664.5" "Group enriched" "Detected in all" 6 "dendritic cells: 664.5;T-cells: 170.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 59 "testis: 38.8" "Cell type enriched" "Detected in some" 7 "Late spermatids: 2583.4" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.2;Gallbladder cancer: 3.4;head and neck cancer: 1.9" "Breast - Breast myoepithelial cells, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "unprognostic (2.59e-3)" "unprognostic (5.49e-2)" "unprognostic (7.94e-3)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (8.99e-2)" "unprognostic (5.96e-2)" "unprognostic (1.62e-1)" "unprognostic (8.01e-2)" "unprognostic (1.36e-4)" "unprognostic (2.37e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" PSMD12 "p55, Rpn5" ENSG00000197170 "Proteasome 26S subunit, non-ATPase 12" O00232 17 67337916-67366605 "Disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023119 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA 73000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Mixed function" 10 Microtubules "Nucleoplasm, Cytosol" "HPA023119: AB_1855845" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.28e-2)" "unprognostic (3.72e-2)" "prognostic favorable (6.32e-4)" "unprognostic (2.63e-1)" "unprognostic (7.32e-3)" "prognostic unfavorable (4.73e-6)" "unprognostic (1.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" ABCC12 MRP9 ENSG00000140798 "ATP binding cassette subfamily C member 12" 16 48080882-48156018 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 1.4;skeletal muscle: 1.4;testis: 2.8" "Group enriched" "Detected in some" 4 "Early spermatids: 4.6;Excitatory neurons: 5.0;Late spermatids: 3.2;Spermatocytes: 4.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043100 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA043100: AB_10794922" "unprognostic (1.53e-1)" "unprognostic (6.87e-2)" "unprognostic (2.37e-2)" "unprognostic (4.62e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (2.65e-1)" "unprognostic (7.53e-2)" "unprognostic (4.23e-1)" PCDH12 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.4;Endothelial cells: 25.7;Hofbauer cells: 32.4;Lymphatic endothelial cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 41 "monocytes: 4.7" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" "Cell adhesion" NA NA 14000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.0" "Cell type enhanced" "Detected in many" "Microglial cells: 28.6;Spermatocytes: 36.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 1 Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" H4C12 "dJ160A22.1, H4/d, H4F2iii, H4FD, HIST1H4K" ENSG00000273542 "H4 clustered histone 12" P62805 6 27831174-27831560 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.9" "Cell type enhanced" "Detected in some" "dendritic cells: 1.8;Gastric mucus-secreting cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 161.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 161.4" "Low cancer specificity" "Detected in all" HPA042201 Supported NA NA 25000000 "Cluster 32: Basophils - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 49: Non-specific - Transcription" 54 "HPA042201: AB_2677898" "unprognostic (3.19e-1)" "unprognostic (9.09e-3)" "unprognostic (1.16e-1)" "unprognostic (4.84e-3)" "unprognostic (9.63e-2)" "unprognostic (9.13e-2)" "unprognostic (1.48e-1)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.79e-2)" "unprognostic (3.13e-2)" "unprognostic (2.79e-1)" "unprognostic (3.45e-1)" "unprognostic (4.16e-2)" "unprognostic (1.02e-1)" KLHL12 C3IP1 ENSG00000117153 "Kelch like family member 12" Q53G59 1 202891116-202928636 "Predicted intracellular proteins" "ER-Golgi transport, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 176.2;Late spermatids: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071324 Supported "Vesicles,Centriolar satellite" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Retina & Testis - Cilium" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 18: Early spermatids - Unknown function" 40 "Vesicles, Centriolar satellite" "HPA071324: AB_2686389" "unprognostic (1.69e-2)" "unprognostic (2.84e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-1)" "unprognostic (1.93e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-3)" "unprognostic (3.35e-2)" "unprognostic (1.15e-2)" "unprognostic (9.11e-2)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (2.20e-3)" "unprognostic (6.22e-2)" "unprognostic (6.01e-2)" "unprognostic (3.32e-1)" "unprognostic (4.87e-2)" RGS12 ENSG00000159788 "Regulator of G protein signaling 12" O14924 4 3293021-3439913 "Plasma proteins, Predicted intracellular proteins" Transcription "GTPase activation, Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 100.4;Inhibitory neurons: 162.2;Suprabasal keratinocytes: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054646, HPA067421" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 69: Neurons - Neuronal signaling" 1 "Nucleoplasm, Nucleoli" Cytosol "HPA054646: AB_2682555, HPA067421: AB_2685836" "unprognostic (2.08e-1)" "unprognostic (1.71e-3)" "unprognostic (7.50e-2)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.03e-4)" "unprognostic (3.43e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (9.02e-2)" "unprognostic (1.70e-2)" "unprognostic (2.13e-1)" "prognostic favorable (8.43e-4)" "unprognostic (2.54e-1)" "unprognostic (2.60e-1)" "unprognostic (5.92e-2)" "unprognostic (1.11e-2)" TEX12 ENSG00000150783 "Testis expressed 12" Q9BXU0 11 112167372-112172556 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "retina: 8.4;testis: 20.1" "Cell type enriched" "Detected in some" 11 "Spermatocytes: 209.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038289, HPA038290" Enhanced NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 28 "HPA038289: AB_10672742, HPA038290: AB_2675934" "unprognostic (1.49e-1)" "unprognostic (6.57e-2)" "unprognostic (1.01e-1)" "unprognostic (2.92e-2)" "unprognostic (1.07e-1)" "unprognostic (2.93e-3)" "unprognostic (2.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (2.91e-1)" "unprognostic (9.20e-4)" "unprognostic (1.71e-2)" "unprognostic (2.97e-1)" "unprognostic (6.54e-2)" "unprognostic (4.10e-2)" "unprognostic (3.16e-3)" C12orf29 DKFZp434N2030 ENSG00000133641 "Chromosome 12 open reading frame 29" Q8N999 12 88033846-88050160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039663 Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "HPA039663: AB_10795253" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (7.80e-2)" "unprognostic (6.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.75e-3)" "unprognostic (4.72e-3)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (8.81e-2)" "unprognostic (6.49e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.29e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" C12orf4 ENSG00000047621 "Chromosome 12 open reading frame 4" Q9NQ89 12 4487735-4538508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037871 Uncertain Approved "Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 11: Late spermatids - Unknown function" 3 "Nuclear bodies" "HPA037871: AB_10670531" "unprognostic (5.88e-2)" "unprognostic (2.81e-1)" "unprognostic (5.64e-2)" "unprognostic (2.51e-2)" "unprognostic (3.07e-2)" "unprognostic (6.69e-2)" "unprognostic (2.96e-3)" "unprognostic (8.59e-2)" "unprognostic (6.85e-2)" "unprognostic (2.75e-2)" "unprognostic (2.26e-2)" "unprognostic (5.93e-2)" "unprognostic (1.26e-2)" "unprognostic (7.83e-2)" "unprognostic (2.74e-1)" "unprognostic (5.02e-2)" "unprognostic (3.92e-1)" C12orf42 FLJ25323 ENSG00000179088 "Chromosome 12 open reading frame 42" Q96LP6 12 103237591-103495978 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 16.7" "Group enriched" "Detected in some" 14 "Early spermatids: 354.8;Late spermatids: 397.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.2;naive B-cell: 5.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Lung - B-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "unprognostic (9.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.96e-2)" "unprognostic (1.05e-2)" "unprognostic (2.66e-1)" "unprognostic (9.83e-2)" "unprognostic (3.39e-2)" "unprognostic (6.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (8.96e-4)" "unprognostic (4.89e-2)" "unprognostic (2.20e-3)" "unprognostic (3.89e-2)" "unprognostic (2.55e-1)" "unprognostic (1.67e-2)" "unprognostic (3.30e-1)" C12orf50 FLJ35821 ENSG00000165805 "Chromosome 12 open reading frame 50" Q8NA57 12 87980035-88034037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 492 "testis: 49.1" "Group enriched" "Detected in some" 42 "Early spermatids: 731.3;Late spermatids: 1408.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" 1 "unprognostic (2.23e-2)" "unprognostic (6.61e-3)" "unprognostic (4.91e-2)" "unprognostic (1.00e-1)" "unprognostic (1.64e-1)" "unprognostic (4.80e-2)" "unprognostic (1.34e-1)" "unprognostic (6.03e-2)" "unprognostic (8.85e-3)" "unprognostic (3.47e-1)" "unprognostic (2.84e-7)" "unprognostic (6.31e-2)" "unprognostic (2.17e-2)" "unprognostic (3.03e-1)" "unprognostic (7.20e-2)" C12orf56 ENSG00000185306 "Chromosome 12 open reading frame 56" Q8IXR9 12 64264762-64390758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.4;testis: 7.3" "Cell type enhanced" "Detected in some" "Early spermatids: 58.6;Late spermatids: 43.0;Oligodendrocytes: 12.6;Proximal tubular cells: 11.2;Spermatocytes: 15.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 15.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.3;thyroid cancer: 1.4" "Kidney - Podocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA056986 Enhanced NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA056986: AB_2683300" "unprognostic (5.85e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (9.24e-2)" "unprognostic (9.35e-4)" "unprognostic (1.79e-4)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (9.51e-2)" "unprognostic (6.22e-3)" "unprognostic (4.00e-2)" "unprognostic (2.38e-4)" "unprognostic (8.86e-2)" "unprognostic (3.91e-2)" "unprognostic (3.40e-2)" "unprognostic (1.69e-2)" C12orf60 MGC47869 ENSG00000182993 "Chromosome 12 open reading frame 60" Q5U649 12 14803666-14906586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.3" "Group enriched" "Detected in many" 11 "Early spermatids: 495.0;Late spermatids: 131.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA042461, HPA043911" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Retina & Testis - Cilium" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 21: Early spermatids - Spermatogenesis" 1 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA042461: , HPA043911: AB_10963941" "unprognostic (3.71e-2)" "unprognostic (7.02e-2)" "unprognostic (1.72e-1)" "unprognostic (6.39e-2)" "unprognostic (4.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (3.09e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (9.42e-2)" "unprognostic (2.17e-1)" "unprognostic (7.09e-2)" "unprognostic (1.85e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-2)" C12orf71 LOC728858 ENSG00000214700 "Chromosome 12 open reading frame 71" A8MTZ7 12 27081057-27082578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;testis: 3.1" "Cell type enriched" "Detected in some" 9 "Early spermatids: 30.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 10 "NK-cells: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA038359, HPA058728" Uncertain Approved Cytosol NA NA "Cluster 4: Testis - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 18: Early spermatids - Unknown function" Cytosol "HPA038359: , HPA058728: AB_2683800" "unprognostic (1.14e-1)" "unprognostic (9.86e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "unprognostic (6.78e-3)" "unprognostic (9.90e-2)" "unprognostic (3.13e-1)" "unprognostic (7.12e-3)" "unprognostic (1.02e-1)" "unprognostic (6.73e-3)" "unprognostic (1.96e-1)" "unprognostic (4.15e-8)" "unprognostic (4.85e-2)" "unprognostic (9.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073636 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 40.5" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 46.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 33: Brain - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" "unprognostic (9.20e-2)" "unprognostic (3.31e-2)" "unprognostic (2.35e-3)" "unprognostic (9.54e-2)" "unprognostic (3.50e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "prognostic favorable (6.44e-5)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698937-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7;tongue: 101.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 53: Fibroblasts - ECM organization" Cytosol "HPA046930: AB_10962836" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.54e-1)" "unprognostic (9.94e-3)" "unprognostic (7.93e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (1.22e-3)" CLEC12A "CD371, CLL-1, DCAL-2, MICL" ENSG00000172322 "C-type lectin domain family 12 member A" Q5QGZ9 12 9951316-9995694 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.8;lymphoid tissue: 21.6" "Cell type enhanced" "Detected in some" "granulocytes: 40.1;Hofbauer cells: 63.8;Kupffer cells: 96.9;Macrophages: 119.6;monocytes: 183.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 203.3" "Group enriched" "Detected in many" 37 "dendritic cells: 72.7;granulocytes: 203.3;monocytes: 137.1" "Cancer enriched" "Detected in some" 16 "Leukemia: 21.6" "Stomach - Macrophages" "Region enriched" "Detected in single" 7 "basal ganglia: 6.2" "Low region specificity" "Detected in single" HPA048515 Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA048515: AB_2680425" "unprognostic (4.74e-2)" "unprognostic (6.06e-3)" "unprognostic (7.76e-2)" "unprognostic (6.88e-2)" "unprognostic (2.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (3.29e-1)" "unprognostic (1.44e-2)" "unprognostic (1.70e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-3)" "unprognostic (9.67e-3)" "unprognostic (7.43e-2)" "unprognostic (3.78e-2)" "prognostic favorable (9.33e-4)" KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "cervix: 105.5;esophagus: 202.8;salivary gland: 62.8;vagina: 96.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 226.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Region enriched" "Detected in single" 18 "choroid plexus: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.1" "Lung - Respiratory ciliated cells, Testis - Late spermatids, Thyroid - Parafollicular cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB025473 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Suprabasal keratinocytes - Cornification" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" C12orf57 "C10, GRCC10" ENSG00000111678 "Chromosome 12 open reading frame 57" Q99622 12 6942978-6946003 "Disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046182, HPA059163, HPA066043" Approved Enhanced "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Ribosome" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 64: Non-specific - Ribosome" 2 "Nuclear speckles" "HPA046182: AB_2679572, HPA059163: AB_2683937, HPA066043: AB_2685603" "unprognostic (5.89e-2)" "unprognostic (1.56e-2)" "unprognostic (2.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.24e-2)" "unprognostic (2.56e-1)" "unprognostic (5.20e-3)" "unprognostic (8.27e-2)" "unprognostic (1.11e-1)" "unprognostic (3.48e-2)" "prognostic favorable (8.74e-4)" "unprognostic (4.25e-2)" "prognostic unfavorable (2.32e-7)" "unprognostic (1.47e-2)" "unprognostic (3.26e-1)" "unprognostic (6.81e-2)" "unprognostic (8.39e-3)" H2AC12 "dJ86C11.1, H2A/S, H2AFALii, HIST1H2AH" ENSG00000274997 "H2A clustered histone 12" Q96KK5 6 27147106-27147562 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 8.6" "Group enriched" "Detected in many" 4 "Erythroid cells: 28.6;Gastric mucus-secreting cells: 18.9;Plasma cells: 28.2" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004030, HPA041189" Supported Supported Nucleoplasm NA Yes "Cluster 34: B-cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" Nucleoplasm "CAB004030: AB_2118804, HPA041189: AB_2677357" "unprognostic (4.07e-1)" "unprognostic (2.73e-3)" "unprognostic (4.04e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.35e-3)" "unprognostic (3.90e-2)" "unprognostic (3.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.38e-3)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (9.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.26e-4)" H2BC12 "H2BFAiii, H2BFT, HIST1H2BK" ENSG00000197903 "H2B clustered histone 12" O60814 6 27146361-27146855 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 43.4;Gastric mucus-secreting cells: 38.9;Oocytes: 22.8;Plasma cells: 52.3;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Sertoli cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 77: Plasma cells - Protein processing" 1 Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.78e-2)" "unprognostic (4.70e-3)" "unprognostic (9.00e-3)" "unprognostic (1.30e-1)" "unprognostic (3.81e-1)" "unprognostic (4.50e-2)" "unprognostic (6.50e-2)" "unprognostic (4.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-3)" "unprognostic (3.46e-3)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (3.93e-2)" "unprognostic (1.49e-1)" "unprognostic (7.59e-2)" "unprognostic (2.37e-2)" H3C12 "H3/j, H3FJ, HIST1H3J" ENSG00000197153 "H3 clustered histone 12" P68431 6 27890315-27893106 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;lymphoid tissue: 1.1" "Group enriched" "Detected in some" 8 "Gastric mucus-secreting cells: 21.8;Plasma cells: 10.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 52 Nucleoplasm "HPA042570: AB_2678056, HPA050968: , HPA064058: " "unprognostic (1.15e-1)" "unprognostic (4.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (3.18e-1)" "unprognostic (1.71e-4)" "unprognostic (2.91e-2)" "unprognostic (4.09e-3)" "unprognostic (6.37e-3)" "unprognostic (6.67e-2)" "unprognostic (4.68e-3)" "unprognostic (1.34e-1)" "unprognostic (2.63e-8)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.82e-3)" "unprognostic (8.04e-2)" HOXD12 HOX4H ENSG00000170178 "Homeobox D12" P35452 2 176099795-176102489 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.4;seminal vesicle: 1.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 6.1;Intestinal goblet cells: 1.4;Paneth cells: 1.5;Undifferentiated cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA059444 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "HPA059444: AB_2684020" "unprognostic (1.00e-1)" "unprognostic (2.40e-3)" "unprognostic (1.32e-2)" "unprognostic (3.53e-2)" "unprognostic (1.71e-2)" "unprognostic (1.36e-2)" "unprognostic (7.11e-2)" "unprognostic (4.54e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 41.5;skeletal muscle: 66.7;tongue: 24.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.2;Horizontal cells: 30.2;Muller glia cells: 9.1;Skeletal myocytes: 19.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Skeletal muscle - Skeletal myocytes" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" C10orf120 bA318C4.1 ENSG00000183559 "Chromosome 10 open reading frame 120" Q5SQS8 10 122697709-122699846 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 154 "testis: 30.1" "Group enriched" "Detected in some" 127 "Early spermatids: 405.0;Late spermatids: 303.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 21: Early spermatids - Spermatogenesis" C1orf122 FLJ45459 ENSG00000197982 "Chromosome 1 open reading frame 122" Q6ZSJ8 1 37806979-37809454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 215.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Non-specific - DNA binding" "unprognostic (7.83e-2)" "unprognostic (4.07e-3)" "unprognostic (1.46e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (1.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.81e-3)" "unprognostic (3.89e-1)" "unprognostic (3.58e-2)" "unprognostic (9.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.81e-4)" C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982076 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.3;skeletal muscle: 16.1" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 14.9;Pancreatic endocrine cells: 13.6" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Region enhanced" "Detected in some" "cerebellum: 2.4" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cancer enriched" "Detected in some" 5 "Myeloma: 6.0" "Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;liver: 39.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.5;Gastric mucus-secreting cells: 57.8;Paneth cells: 45.3;Proximal enterocytes: 113.7;Suprabasal keratinocytes: 40.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.2;eosinophil: 14.9" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.0;Gastric cancer: 5.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Urothelial cells, Thyroid - Fibroblasts" HPA058960 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" DCAF12L2 WDR40C ENSG00000198354 "DDB1 and CUL4 associated factor 12 like 2" Q5VW00 X 126163499-126166289 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.9" "Cell type enhanced" "Detected in some" "Leydig cells: 3.4;Oocytes: 5.1;Ovarian stromal cells: 1.9;Peritubular cells: 4.0;Prostatic glandular cells: 2.8;Sertoli cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;prostate cancer: 1.3" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 6: Ovarian stromal cells - Transcription" Cytosol "HPA044737: AB_2679067, HPA048981: AB_2680586, HPA053138: AB_2682054" "unprognostic (1.16e-4)" "unprognostic (8.83e-3)" "unprognostic (2.93e-1)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "unprognostic (3.02e-1)" "unprognostic (3.34e-3)" "unprognostic (1.16e-1)" "unprognostic (8.47e-4)" "unprognostic (1.56e-2)" "unprognostic (4.05e-2)" "unprognostic (3.86e-2)" "unprognostic (2.51e-1)" HOXC12 "HOC3F, HOX3, HOX3F" ENSG00000123407 "Homeobox C12" P31275 12 53954903-53958956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 16 "adipose tissue: 1.2;skin 1: 2.8" "Cell type enriched" "Detected in single" 6 "Melanocytes: 3.4" "Cancer enhanced" "Detected in some" "breast cancer: 1.8;stomach cancer: 2.0" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 14.8;breast cancer: 8.8" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA055632 Uncertain NA NA "Cluster 13: Skin - Cornification" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 65: Non-specific - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA055632: AB_2682867" "unprognostic (6.95e-2)" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.37e-2)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.17e-3)" "unprognostic (3.84e-2)" "unprognostic (2.55e-1)" RNF212 "FLJ38841, LOC285498" ENSG00000178222 "Ring finger protein 212" Q495C1 4 1056250-1113564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 8.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 24.6;Oocytes: 60.3;Ovarian stromal cells: 25.8;Spermatocytes: 53.2;Spermatogonia: 39.7" "Cancer enhanced" "Detected in many" "cervical cancer: 5.3;ovarian cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 24.9;Gallbladder cancer: 27.8" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA057527 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 6: Ovarian stromal cells - Transcription" "HPA057527: AB_2683457" "unprognostic (2.75e-2)" "prognostic favorable (1.39e-4)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (1.10e-2)" "unprognostic (2.57e-2)" "unprognostic (4.49e-2)" "unprognostic (1.33e-1)" "unprognostic (2.09e-2)" "unprognostic (2.68e-1)" "unprognostic (1.12e-2)" "unprognostic (3.45e-2)" "unprognostic (7.65e-2)" "unprognostic (8.36e-2)" "unprognostic (1.60e-1)" "unprognostic (5.52e-2)" "unprognostic (1.05e-1)" RNF212B C14orf164 ENSG00000215277 "Ring finger protein 212B" A8MTL3 14 23185316-23273477 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 25.0" "Group enriched" "Detected in some" 4 "Early spermatids: 59.4;Spermatocytes: 93.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Spermatocytes" "Not detected" "Not detected" HPA053574 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053574: AB_2682195" "unprognostic (2.88e-1)" "unprognostic (2.17e-1)" "unprognostic (4.65e-1)" "unprognostic (8.54e-2)" "unprognostic (1.30e-1)" "unprognostic (4.79e-1)" "unprognostic (4.48e-2)" "unprognostic (2.98e-2)" "unprognostic (3.82e-1)" "unprognostic (1.83e-2)" "unprognostic (4.96e-3)" "unprognostic (4.45e-1)" "unprognostic (7.33e-5)" "unprognostic (9.60e-2)" "unprognostic (3.40e-1)" "unprognostic (7.56e-2)" "unprognostic (5.39e-3)" NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" 10 "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 472.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 259.2;eosinophil: 460.0;neutrophil: 230.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 460.0" "Cancer enhanced" "Detected in all" "Myeloma: 366.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 5500000 "Cluster 22: Eosinophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Nucleoplasm, Nucleoli rim" "CAB011507: AB_2117984, HPA055907: AB_2682966" "unprognostic (4.43e-2)" "unprognostic (1.57e-3)" "unprognostic (1.31e-2)" "unprognostic (2.96e-2)" "unprognostic (5.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.85e-1)" "unprognostic (8.93e-2)" "unprognostic (3.08e-1)" "prognostic favorable (8.06e-5)" H2BC12L "H2BFS, H2BS1" ENSG00000234289 "H2B clustered histone 12 like" P57053 21 43565182-43565648 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Adrenocortical cancer: 4.9" "Not detected" "Not detected" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (2.06e-2)" MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.2;lymphoid tissue: 39.3;urinary bladder: 15.5" "Group enriched" "Detected in some" 9 "Extravillous trophoblasts: 344.9;Langerhans cells: 117.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.7;head and neck cancer: 1.3;lymphoma: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 70: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 246.1" "Cell type enriched" "Detected in some" 15 "Distal enterocytes: 928.6" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 4086.5;skeletal muscle: 2965.6;tongue: 2000.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 7255.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "CAB004503: AB_2282358, HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.14e-3)" "unprognostic (5.30e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (3.03e-2)" "unprognostic (7.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.57e-3)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-1)" "unprognostic (9.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (4.58e-3)" "unprognostic (7.13e-2)" TMEM126B HT007 ENSG00000171204 "Transmembrane protein 126B" Q8IUX1 11 85628573-85636539 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014480, HPA019186" Uncertain Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA014480: AB_1858083, HPA019186: AB_1858084" "unprognostic (1.11e-1)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (5.67e-1)" "unprognostic (1.44e-1)" "unprognostic (5.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-2)" "unprognostic (6.70e-3)" "unprognostic (4.42e-2)" "unprognostic (4.30e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (5.86e-2)" "unprognostic (2.66e-2)" DEFB121 DEFB-21 ENSG00000204548 "Defensin beta 121" Q5J5C9 20 31404845-31412838 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11981 "epididymis: 2536.7" "Group enriched" "Detected in some" 23 "Early spermatids: 17.1;Late spermatids: 5.0;Spermatocytes: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA079460 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 8 "HPA079460: " RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 106.4" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Bipolar cells: 6.9;Excitatory neurons: 18.9;Inhibitory neurons: 11.1;Muller glia cells: 6.5;Oligodendrocyte precursor cells: 12.7" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 15.4" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 18 "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3451.3" "Group enriched" "Detected in many" 9 "Hofbauer cells: 388.2;Kupffer cells: 667.6;Macrophages: 386.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Region enhanced" "Detected in many" "cerebral cortex: 7.2" "Group enriched" "Detected in many" 13 "classical monocyte: 1326.0;neutrophil: 1795.5" "Group enriched" "Detected in many" 13 "granulocytes: 1795.5;monocytes: 1326.0" "Group enriched" "Detected in some" 5 "cervical cancer: 3.9;head and neck cancer: 5.5;Leukemia: 2.0" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Region enhanced" "Detected in some" "cerebral cortex: 5.5" "HPA002881, CAB025872" Enhanced "Secreted to blood" Immunity NA NA 28500000 8300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 34: B-cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 6 "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" ENSG00000251012 ENSG00000251012 "Novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)" 3 119147375-119187807 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.7;lymphoid tissue: 15.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.7;Extravillous trophoblasts: 27.7;Oocytes: 19.1;Plasma cells: 22.7;Spermatocytes: 66.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Non-specific - Cell proliferation" 2 "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.1;lymphoid tissue: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 31.0;Extravillous trophoblasts: 12.3;Oocytes: 27.2;Plasma cells: 10.2;Undifferentiated cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 52: Non-specific - Cell proliferation" 1 "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" C6orf62 "DKFZP564G182, FLJ12619, XTP12" ENSG00000112308 "Chromosome 6 open reading frame 62" Q9GZU0 6 24704861-24719998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 320.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030564, HPA030566" Supported Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" Cytosol "HPA030564: AB_10600000, HPA030566: AB_10599425" "unprognostic (2.07e-2)" "unprognostic (2.92e-1)" "unprognostic (7.10e-2)" "unprognostic (6.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (1.18e-1)" "unprognostic (3.67e-1)" "prognostic favorable (4.04e-4)" "unprognostic (4.16e-3)" "unprognostic (3.94e-2)" "unprognostic (3.08e-2)" "unprognostic (9.01e-2)" "unprognostic (4.03e-1)" "unprognostic (1.93e-2)" "prognostic favorable (3.62e-6)" SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4;kidney: 36.7;testis: 71.9" "Cell type enhanced" "Detected in many" "Early spermatids: 119.7;Erythroid cells: 31.1;Late spermatids: 34.2;Spermatocytes: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 11.7;T-reg: 5.0" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 5.0" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 40 "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 3 Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 58.5" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 43.9;Erythroid cells: 67.8;Extravillous trophoblasts: 91.8;Hofbauer cells: 24.0;Plasma cells: 25.9;Undifferentiated cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Thyroid - Mitotic cells (Thyroid)" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 17 Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.4;Spermatocytes: 115.7;Spermatogonia: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 6.2;classical monocyte: 14.6;intermediate monocyte: 4.5;myeloid DC: 10.9;neutrophil: 10.9" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 10.9;monocytes: 14.6" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 38 "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, GLP, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618992-137870016 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Plasma cells - Humoral immune response" 2 "Nucleoplasm, Nuclear bodies" "HPA060022: AB_2684190, HPA074729: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favorable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609291-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 52.1;Spermatogonia: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" 4 Nucleoplasm "CAB018351: AB_675504, HPA049808: AB_2680892, HPA062476: AB_2684775" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-2)" "unprognostic (8.25e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.07e-2)" "unprognostic (7.99e-2)" "unprognostic (2.35e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.87e-3)" "unprognostic (1.88e-1)" "unprognostic (3.07e-1)" "unprognostic (8.05e-2)" IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.1;lymphoid tissue: 3.7;skin 1: 7.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.6;Brain cancer: 3.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" Interleukin NA NA 8560 "Cluster 13: Skin - Cornification" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041, HPA057220" Uncertain Uncertain "Endoplasmic reticulum,Vesicles" NA Yes "Cluster 80: Non-specific - Endocytosis" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" Vesicles "HPA011318: AB_2668482, HPA054041: AB_2682353, HPA057220: " "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 96.0" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 57 Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" CLDN17 "MGC126552, MGC126554" ENSG00000156282 "Claudin 17" P56750 21 30165565-30166805 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 2.3;esophagus: 6.0;salivary gland: 6.2;vagina: 7.0" "Group enriched" "Detected in some" 4 "Early spermatids: 6.5;Suprabasal keratinocytes: 5.7" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045903 Enhanced NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA045903: AB_2679491" "unprognostic (2.41e-1)" ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 64.7;Spermatocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 44: Oocytes - Unknown function" 9 Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, Sec15, SEC15L, SEC15L1" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 159.1" "Cell type enhanced" "Detected in all" "Excitatory neurons: 175.5;Microglial cells: 139.6;Oligodendrocyte precursor cells: 147.6;Rod photoreceptor cells: 153.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 66: Photoreceptor cells - Visual perception" 11 Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093991-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA035373: AB_10794630" "unprognostic (9.81e-3)" "unprognostic (3.33e-1)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.47e-2)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" SLF2 "C10orf6, FAM178A, FLJ10512, FLJ25012" ENSG00000119906 "SMC5-SMC6 complex localization factor 2" Q8IX21 10 100912963-100965134 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 107.3;Oligodendrocytes: 187.9;Peritubular cells: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038499, HPA057568" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 6: Ovarian stromal cells - Transcription" 6 "Nucleoplasm, Vesicles" "HPA038499: AB_10672520, HPA057568: AB_2683471" "unprognostic (9.05e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-2)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (2.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.66e-2)" "unprognostic (1.54e-2)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (4.90e-2)" "unprognostic (1.39e-1)" "unprognostic (2.41e-1)" SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 127.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 220.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 15 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: AB_2677353, HPA044248: AB_2678873" "unprognostic (7.87e-2)" "prognostic favorable (1.95e-4)" "unprognostic (6.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.04e-1)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (8.99e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.03e-3)" CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 37.8;testis: 21.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 46.7;Extravillous trophoblasts: 26.7;Oocytes: 76.5;Spermatocytes: 79.0;Spermatogonia: 36.7;Undifferentiated cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Non-specific - Cell proliferation" 14 Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" LRIF1 "C1orf103, FLJ11269, RIF1" ENSG00000121931 "Ligand dependent nuclear receptor interacting factor 1" Q5T3J3 1 110947190-110963965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044515 Uncertain Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: B-cells - B-cell function" 20 Nucleoplasm "Centriolar satellite" "HPA044515: AB_10796800" "unprognostic (5.06e-2)" "unprognostic (4.82e-2)" "unprognostic (4.74e-1)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.73e-4)" "unprognostic (5.14e-2)" "unprognostic (9.23e-3)" "unprognostic (3.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (2.70e-1)" LLPH "C12orf31, hLLP, MGC14817" ENSG00000139233 "LLP homolog, long-term synaptic facilitation factor" Q9BRT6 12 66116555-66130750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048920, HPA058786" Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoli "Mitotic chromosome" "HPA048920: AB_2680556, HPA058786: AB_2683820" "unprognostic (3.60e-3)" "unprognostic (4.94e-2)" "unprognostic (4.07e-2)" "unprognostic (3.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.31e-2)" "prognostic unfavorable (6.44e-7)" "unprognostic (7.15e-2)" "unprognostic (1.30e-2)" "unprognostic (8.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.07e-2)" "unprognostic (3.87e-2)" "unprognostic (9.65e-3)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (2.94e-2)" AKAP8 "AKAP95, DKFZp586B1222" ENSG00000105127 "A-kinase anchoring protein 8" O43823 19 15353385-15379815 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Protein transport, Transcription, Transcription regulation, Transport" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004776 Supported Supported Nucleoplasm NA NA 10000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 8 Nucleoplasm "HPA004776: AB_1078122" "unprognostic (9.04e-3)" "unprognostic (3.67e-3)" "unprognostic (1.03e-1)" "unprognostic (4.17e-2)" "unprognostic (8.03e-2)" "unprognostic (1.77e-2)" "unprognostic (4.13e-2)" "unprognostic (3.17e-2)" "unprognostic (3.34e-3)" "unprognostic (1.27e-1)" "unprognostic (2.82e-1)" "unprognostic (1.78e-3)" "unprognostic (5.04e-3)" "unprognostic (1.22e-2)" "unprognostic (3.57e-1)" "unprognostic (6.06e-2)" "unprognostic (3.83e-2)" C11orf54 PTD012 ENSG00000182919 "Chromosome 11 open reading frame 54" Q9H0W9 11 93741591-93764749 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 547.7;liver: 250.6" "Group enriched" "Detected in all" 4 "Hepatocytes: 342.9;Proximal tubular cells: 1119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040088, HPA040511" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA 1300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 3 "Nuclear bodies" Nucleoplasm "HPA040088: AB_10795518, HPA040511: AB_10795369" "unprognostic (3.32e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.82e-2)" "unprognostic (1.90e-2)" "unprognostic (2.81e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-3)" "unprognostic (1.58e-1)" "prognostic favorable (5.06e-6)" "unprognostic (2.19e-1)" "unprognostic (6.10e-2)" "unprognostic (2.41e-2)" "unprognostic (6.53e-3)" MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 60.1;Spermatogonia: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 2 Nucleoplasm Cytosol "HPA045141: AB_2679230, HPA066433: " "unprognostic (6.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (5.78e-2)" "prognostic unfavorable (9.30e-8)" "unprognostic (5.21e-2)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (3.47e-1)" NSL1 "C1orf48, DC8, DKFZP566O1646, MIS14" ENSG00000117697 "NSL1 component of MIS12 kinetochore complex" Q96IY1 1 212726153-212791782 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045761, HPA053721" Enhanced Supported "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 4 "Nuclear speckles" "HPA045761: AB_2679444, HPA053721: AB_2682240" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (8.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.58e-2)" "unprognostic (1.78e-2)" "unprognostic (8.22e-3)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (6.09e-3)" "unprognostic (3.44e-3)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (2.59e-1)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (6.66e-2)" RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036887, HPA036888" Supported Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" 4 Nucleoplasm "Nuclear membrane, Plasma membrane" "HPA036887: AB_2675361, HPA036888: AB_2675362" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.71e-1)" "unprognostic (4.71e-3)" "unprognostic (5.87e-2)" "unprognostic (1.79e-2)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-2)" "unprognostic (2.84e-2)" "unprognostic (1.80e-3)" "unprognostic (4.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.41e-2)" SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 2 "HPA059235: AB_2683953" "unprognostic (2.67e-1)" "unprognostic (6.42e-3)" "unprognostic (9.69e-3)" "unprognostic (5.93e-3)" "unprognostic (2.07e-1)" "unprognostic (4.44e-2)" "unprognostic (7.70e-3)" "unprognostic (9.81e-2)" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (3.96e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.59e-1)" "unprognostic (1.39e-1)" "unprognostic (4.75e-3)" "unprognostic (1.05e-1)" KANSL1 "CENP-36, DKFZP727C091, KIAA1267, MSL1v1, NSL1" ENSG00000120071 "KAT8 regulatory NSL complex subunit 1" Q7Z3B3 17 46029916-46225389 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 323.3;Oligodendrocytes: 322.2;Rod photoreceptor cells: 319.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006874, HPA007208" Approved Supported Nucleoplasm No No "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 22 Nucleoplasm "HPA006874: AB_1852393, HPA007208: AB_1852395" "unprognostic (2.46e-1)" "unprognostic (2.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-2)" "unprognostic (4.45e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (1.54e-2)" "unprognostic (9.28e-2)" "unprognostic (7.79e-3)" "unprognostic (2.01e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-2)" "unprognostic (6.13e-2)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (1.33e-2)" C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 174.6;Late spermatids: 73.7;Oocytes: 73.5;Spermatocytes: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Testis - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 13: Non-specific - Mixed function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" C2orf92 LINC01125 ENSG00000228486 "Chromosome 2 open reading frame 92" A0A1B0GVN3 2 97664217-97703066 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.7;testis: 11.4" "Group enriched" "Detected in many" 18 "Early spermatids: 273.4;Late spermatids: 80.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 18: Early spermatids - Unknown function" "unprognostic (5.53e-2)" "unprognostic (8.76e-2)" "unprognostic (1.65e-2)" "unprognostic (2.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.09e-3)" "unprognostic (9.29e-2)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.98e-3)" "unprognostic (2.76e-2)" "unprognostic (7.45e-7)" "unprognostic (5.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (5.23e-5)" CENPO "CENP-O, MGC11266" ENSG00000138092 "Centromere protein O" Q9BU64 2 24793136-24822376 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.1;Oocytes: 9.6;Spermatocytes: 10.3;Spermatogonia: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046189 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 3 Nucleoplasm "Nuclear bodies" "HPA046189: AB_2679579" "unprognostic (1.67e-2)" "unprognostic (2.42e-1)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.79e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.56e-2)" "unprognostic (4.02e-1)" "unprognostic (4.81e-2)" "unprognostic (5.93e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.71e-13)" "unprognostic (4.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" CHTF18 "C16orf41, C321D2.4, CHL12, Ctf18" ENSG00000127586 "Chromosome transmission fidelity factor 18" Q8WVB6 16 788046-800737 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.1;Erythroid cells: 20.0;Extravillous trophoblasts: 20.1;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA040976, HPA056209" Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" Nucleoplasm Cytosol "HPA040976: AB_2677232, HPA056209: AB_2683066" "unprognostic (3.83e-2)" "unprognostic (4.97e-2)" "unprognostic (4.25e-2)" "unprognostic (9.35e-2)" "unprognostic (4.59e-2)" "unprognostic (3.02e-3)" "unprognostic (1.80e-3)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.19e-1)" "unprognostic (4.00e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (1.43e-8)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (9.89e-2)" "prognostic favorable (2.78e-4)" DESI2 "C1orf121, CGI-146, DESI-2, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244653103-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 200.1;Spermatocytes: 177.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 10 Vesicles "HPA049950: AB_2680969" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.8;lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "Early spermatids: 20.8;Erythroid cells: 39.8;Oocytes: 103.7;Spermatocytes: 32.9;Spermatogonia: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008436, HPA027261" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Non-specific - Cell proliferation" 15 "Nucleoplasm, Nucleoli" Cytosol "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 138.3;Leydig cells: 158.6;Peritubular cells: 202.3;Sertoli cells: 514.0;Smooth muscle cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 36.3;testis cancer: 35.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 33: Non-specific - ATP binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 21 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PDS5A "KIAA0648, PIG54, SCC-112" ENSG00000121892 "PDS5 cohesin associated factor A" Q29RF7 4 39822863-39977956 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036661, HPA036662" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" 7 Nucleoplasm "HPA036661: AB_2675233, HPA036662: AB_10696783" "unprognostic (4.18e-2)" "unprognostic (1.42e-1)" "unprognostic (1.62e-3)" "unprognostic (6.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (9.97e-3)" "unprognostic (2.97e-1)" "unprognostic (6.67e-3)" "unprognostic (3.19e-2)" "unprognostic (2.59e-2)" "unprognostic (5.74e-2)" "unprognostic (2.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.99e-1)" "unprognostic (2.51e-1)" "unprognostic (3.81e-2)" SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 225.2" "Cell type enhanced" "Detected in many" "B-cells: 190.8;dendritic cells: 266.3;NK-cells: 165.9;T-cells: 194.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 212.4;lymphoma: 198.6;Myeloma: 126.1;Neuroblastoma: 108.4" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Supported Supported Cytosol NA NA 2900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 17 Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (6.35e-3)" "unprognostic (1.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-1)" "unprognostic (1.73e-1)" "unprognostic (6.23e-2)" "unprognostic (2.13e-1)" "unprognostic (7.24e-2)" "unprognostic (6.27e-2)" "unprognostic (1.46e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-1)" "unprognostic (2.88e-1)" "unprognostic (1.92e-1)" "unprognostic (2.60e-2)" TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4360028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 27.2;Excitatory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 20.2" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 4 Cytosol "CAB034010: AB_1128227, HPA040354: AB_2676935, HPA044111: AB_2678814" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" RSL1D1 "CSIG, DKFZP564M182, L12, PBK1, UTP30" ENSG00000171490 "Ribosomal L1 domain containing 1" O76021 16 11833850-11851580 "Predicted intracellular proteins, Ribosomal proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043483 Supported Enhanced "Nucleoli rim,Mitotic chromosome" Yes No 18000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" "HPA043483: AB_2678504" "unprognostic (4.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.23e-2)" "unprognostic (8.88e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.95e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (6.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.28e-1)" "unprognostic (2.24e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.24e-4)" "unprognostic (4.72e-2)" "unprognostic (1.36e-1)" "unprognostic (2.02e-2)" "unprognostic (2.68e-2)" BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.9" "Cell type enhanced" "Detected in many" "Spermatogonia: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: AB_2680193, HPA066764: AB_2685716" "unprognostic (6.92e-2)" "unprognostic (5.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "unprognostic (3.32e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (3.35e-5)" "unprognostic (2.25e-2)" "unprognostic (4.14e-1)" "unprognostic (3.31e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.23e-7)" "unprognostic (7.83e-2)" "unprognostic (4.33e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-3)" GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.9;Basal squamous epithelial cells: 15.1;Gastric mucus-secreting cells: 33.6;Oligodendrocytes: 14.7;Plasma cells: 27.8;Squamous epithelial cells: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019765 Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 10 "Nucleoplasm, Cytosol" "Nucleoli, Mitotic chromosome" "HPA019765: AB_1845750" "unprognostic (2.80e-2)" "unprognostic (2.40e-2)" "unprognostic (2.10e-2)" "unprognostic (9.66e-4)" "unprognostic (9.86e-2)" "unprognostic (8.64e-2)" "unprognostic (4.10e-2)" "unprognostic (1.74e-1)" "unprognostic (2.59e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "unprognostic (8.18e-2)" "unprognostic (1.26e-1)" "unprognostic (5.93e-2)" "unprognostic (9.47e-2)" TP53TG5 "C20orf10, CLG01, dJ453C12.5" ENSG00000124251 "TP53 target 5" Q9Y2B4 20 45372557-45407889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.3" "Group enriched" "Detected in some" 47 "Early spermatids: 495.3;Late spermatids: 421.1;Oligodendrocytes: 146.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041979, HPA058510, HPA077455" Enhanced Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 44: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 21: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA041979: AB_2677778, HPA058510: , HPA077455: " "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.29e-3)" "unprognostic (3.10e-3)" "unprognostic (9.26e-2)" "unprognostic (3.56e-2)" "unprognostic (1.72e-5)" "unprognostic (2.09e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.72e-4)" "unprognostic (1.41e-1)" AGO3 "EIF2C3, FLJ12765, hAGO3" ENSG00000126070 "Argonaute RISC catalytic component 3" Q9H9G7 1 35930718-36072500 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 145.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048342, HPA067849, HPA075436" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 40: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 7 "Cytoplasmic bodies" "Nucleoplasm, Cytosol" "HPA048342: AB_2680365, HPA067849: , HPA075436: AB_2686750" "unprognostic (4.10e-2)" "unprognostic (7.10e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (1.89e-2)" "unprognostic (2.12e-2)" "unprognostic (4.39e-4)" "unprognostic (5.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.30e-1)" "unprognostic (4.97e-2)" "unprognostic (2.96e-2)" "unprognostic (9.28e-3)" "unprognostic (1.61e-1)" "unprognostic (4.45e-2)" "unprognostic (9.06e-2)" "unprognostic (1.81e-1)" ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 151.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 50.3;Cardiomyocytes: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 83.2" "Skeletal muscle - Fibroblasts, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 34: B-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 18: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" C18orf25 "Ark2N, ARKL1, MGC12909, RNF111L1" ENSG00000152242 "Chromosome 18 open reading frame 25" Q96B23 18 46173553-46266992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051314, HPA051899" Approved Approved Nucleoplasm,Cytosol No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 6 Nucleoplasm Cytosol "HPA051314: AB_2681438, HPA051899: AB_2681657" "unprognostic (1.44e-2)" "unprognostic (2.32e-1)" "unprognostic (2.08e-2)" "unprognostic (5.77e-3)" "unprognostic (4.46e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.97e-1)" "unprognostic (7.46e-2)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" "unprognostic (5.80e-2)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 22.6;epididymis: 8.2;ovary: 8.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 38.2;Mesothelial cells: 31.6;Ovarian stromal cells: 17.9" "Cancer enriched" "Detected in some" 6 "glioma: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016899 Enhanced "Secreted - unknown location" "No annotated function" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" "HPA016899: AB_1845704" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (1.23e-1)" "unprognostic (4.37e-3)" "unprognostic (9.56e-2)" "unprognostic (3.05e-3)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" C5orf49 LOC134121 ENSG00000215217 "Chromosome 5 open reading frame 49" A4QMS7 5 7830378-7851151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.3;choroid plexus: 72.4;fallopian tube: 73.2;testis: 36.1" "Group enriched" "Detected in many" 6 "Ciliated cells: 505.5;Early spermatids: 774.0;Late spermatids: 497.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.8" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043759 Enhanced NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 4 "HPA043759: AB_2678655" "unprognostic (1.55e-1)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.13e-3)" "unprognostic (4.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (7.93e-2)" "unprognostic (7.54e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-2)" "unprognostic (2.20e-2)" C7orf50 "MGC11257, YCR016W" ENSG00000146540 "Chromosome 7 open reading frame 50" Q9BRJ6 7 996986-1138260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052281 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 4 "Nucleoplasm, Nucleoli" "Nucleoli rim" "HPA052281: AB_2681784" "unprognostic (1.64e-1)" "unprognostic (1.48e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (1.79e-2)" "unprognostic (1.28e-3)" "unprognostic (2.57e-3)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "prognostic favorable (6.20e-6)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (3.37e-2)" "unprognostic (8.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.33e-2)" CEP19 "C3orf34, MGC14126" ENSG00000174007 "Centrosomal protein 19" Q96LK0 3 196706277-196712250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 81.3;Spermatocytes: 61.0;Spermatogonia: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 50.9;eosinophil: 58.8;neutrophil: 143.9" "Lineage enriched" "Detected in all" 13 "granulocytes: 143.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047614, HPA071138" Enhanced Supported Nucleoplasm,Centrosome NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 41 Centrosome Nucleoplasm "HPA047614: AB_2680103, HPA071138: AB_2686348" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (5.11e-2)" "unprognostic (9.31e-2)" "unprognostic (5.51e-3)" "unprognostic (4.66e-2)" "unprognostic (3.56e-4)" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (2.36e-2)" "unprognostic (1.91e-1)" "unprognostic (3.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.33e-2)" CIAO2B "CGI-128, CIA2B, FAM96B, MIP18" ENSG00000166595 "Cytosolic iron-sulfur assembly component 2B" Q9Y3D0 16 66932065-66934423 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041501, HPA041736" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 19 "Nucleoplasm, Cytosol" "HPA041501: AB_10795123, HPA041736: AB_10793932" "unprognostic (2.49e-1)" "unprognostic (3.79e-2)" "unprognostic (8.06e-2)" "unprognostic (5.42e-3)" "unprognostic (3.93e-2)" "unprognostic (4.91e-2)" "unprognostic (4.98e-2)" "unprognostic (8.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.96e-2)" "unprognostic (5.10e-2)" "unprognostic (1.50e-1)" "unprognostic (9.84e-2)" "unprognostic (6.48e-2)" "unprognostic (1.12e-2)" CLEC7A "CD369, CLECSF12, DECTIN-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 82.8;lung: 30.0;lymphoid tissue: 43.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 185.8;Kupffer cells: 344.2;Langerhans cells: 334.7;Macrophages: 238.2;monocytes: 818.0;Schwann cells: 228.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 251.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 11 "Myeloma: 62.2" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 11 "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" DCLRE1B "APOLLO, FLJ12810, FLJ13998, SNM1B" ENSG00000118655 "DNA cross-link repair 1B" Q9H816 1 113904619-113914086 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 17.6;Langerhans cells: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064934 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 52: Non-specific - Cell proliferation" 8 "Nucleoplasm, Nuclear bodies" "HPA064934: AB_2685387" "unprognostic (1.21e-1)" "unprognostic (3.38e-2)" "unprognostic (4.47e-3)" "unprognostic (4.92e-3)" "unprognostic (1.89e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (4.50e-5)" "unprognostic (1.31e-2)" "unprognostic (9.67e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (6.70e-4)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.03e-7)" "unprognostic (1.24e-2)" "unprognostic (2.13e-1)" "unprognostic (1.25e-1)" "unprognostic (5.08e-2)" FAM186B "C12orf25, DKFZP434J0113" ENSG00000135436 "Family with sequence similarity 186 member B" Q8IYM0 12 49582885-49605639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 44.7" "Group enriched" "Detected in some" 26 "Early spermatids: 88.1;Late spermatids: 98.2;Spermatocytes: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039736, HPA040028" Uncertain NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA039736: AB_10795295, HPA040028: AB_10795684" "unprognostic (2.96e-1)" "unprognostic (1.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.94e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" "unprognostic (1.53e-1)" "unprognostic (3.37e-3)" "unprognostic (1.44e-1)" "unprognostic (4.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-1)" "unprognostic (4.42e-5)" "unprognostic (1.56e-1)" "unprognostic (6.18e-2)" "unprognostic (2.10e-5)" "unprognostic (7.23e-2)" FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 31.3;Cone photoreceptor cells: 39.1;Early spermatids: 26.1;Horizontal cells: 39.0;Oligodendrocytes: 73.1;Rod photoreceptor cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 49.6" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" FLACC1 ALS2CR12 ENSG00000155749 "Flagellum associated containing coiled-coil domains 1" Q96Q35 2 201288271-201357398 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 8.7;testis: 16.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 142.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035793 Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Ciliated cells - Cilium assembly" 3 "Plasma membrane, Cytosol" "HPA035793: AB_10602429" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.40e-3)" "unprognostic (1.40e-5)" "unprognostic (1.37e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-1)" "unprognostic (6.23e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (2.23e-1)" "unprognostic (8.25e-2)" GSKIP C14orf129 ENSG00000100744 "GSK3B interacting protein" Q9P0R6 14 96363452-96387288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 281.3;Late spermatids: 385.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043054, HPA046782" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" 2 "Golgi apparatus, Vesicles" Nucleoli "HPA043054: AB_2678293, HPA046782: AB_2679803" "unprognostic (3.48e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (6.23e-3)" "unprognostic (1.11e-1)" "unprognostic (9.35e-2)" "unprognostic (1.16e-3)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" "unprognostic (8.74e-3)" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" H2AC16 "dJ193B12.9, H2A/i, H2AFI, HIST1H2AL" ENSG00000276903 "H2A clustered histone 16" P0C0S8 6 27865317-27865798 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "bone marrow: 7.5" "Group enriched" "Detected in many" 4 "Erythroid cells: 12.9;Gastric mucus-secreting cells: 36.6;Plasma cells: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 6: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 13 Nucleoplasm "HPA041189: AB_2677357" "unprognostic (2.45e-2)" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.46e-3)" "unprognostic (3.17e-1)" "unprognostic (1.82e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-2)" "unprognostic (4.18e-1)" "unprognostic (2.38e-1)" "unprognostic (4.01e-2)" "unprognostic (4.29e-1)" "unprognostic (2.41e-2)" "unprognostic (2.12e-1)" "unprognostic (6.21e-2)" IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 5 "Langerhans cells: 1470.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Region enhanced" "Detected in many" "cerebral cortex: 14.5" "Immune cell enriched" "Detected in some" 26 "neutrophil: 378.7" "Lineage enriched" "Detected in many" 26 "granulocytes: 378.7" "Cancer enhanced" "Detected in many" "lymphoma: 66.7" "Adipose visceral - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" Receptor NA NA 7130000 27000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" INO80 "hINO80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex ATPase subunit" Q9ULG1 15 40978880-41116280 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041417, HPA041484" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 5 "Nucleoplasm, Nuclear bodies" Cytosol "HPA041417: AB_2677466, HPA041484: AB_2677506" "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favorable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" MAEL "CT128, FLJ14904, SPATA35" ENSG00000143194 "Maelstrom spermatogenic transposon silencer" Q96JY0 1 166975582-167022214 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 154.6" "Group enriched" "Detected in some" 5 "Early spermatids: 1480.4;Late spermatids: 523.1;Spermatocytes: 513.3" "Cancer enhanced" "Detected in many" "testis cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gallbladder cancer: 7.6;Myeloma: 9.1;Uterine cancer: 7.2" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Region enriched" "Detected in single" 5 "thalamus: 1.1" "Low region specificity" "Detected in some" HPA078602 Approved NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" "HPA078602: AB_2732386" "unprognostic (1.36e-1)" "unprognostic (7.01e-2)" "unprognostic (5.81e-2)" "unprognostic (3.15e-1)" "unprognostic (9.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.68e-3)" "unprognostic (4.99e-2)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (3.04e-1)" "unprognostic (8.88e-2)" "unprognostic (5.49e-2)" "unprognostic (1.26e-1)" "unprognostic (3.32e-1)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" MCPH1 "BRIT1, FLJ12847" ENSG00000147316 "Microcephalin 1" Q8NEM0 8 6406592-6648508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.9;Inhibitory neurons: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008238, CAB012177" Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 55: Non-specific - Transcription" 2 "CAB012177: AB_303207, HPA008238: AB_1853655" "unprognostic (1.00e-1)" "unprognostic (2.17e-2)" "prognostic favorable (8.52e-4)" "unprognostic (6.45e-2)" "unprognostic (1.16e-2)" "unprognostic (1.19e-2)" "unprognostic (1.14e-2)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (4.79e-2)" "unprognostic (5.55e-3)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (4.79e-2)" "unprognostic (2.94e-1)" MEIOB "C16orf73, MGC35212" ENSG00000162039 "Meiosis specific with OB-fold" Q8N635 16 1833986-1872178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 26.5" "Cell type enriched" "Detected in some" 9 "Spermatocytes: 491.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 19.3;Rhabdoid: 21.3" "Adipose visceral - Mesothelial cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (7.18e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-2)" "unprognostic (9.73e-2)" "unprognostic (1.67e-1)" "unprognostic (7.68e-3)" "unprognostic (2.00e-2)" "unprognostic (2.68e-2)" "unprognostic (7.30e-3)" "unprognostic (1.34e-1)" "unprognostic (3.80e-1)" "unprognostic (2.18e-3)" MX1 "IFI-78K, lncMX1-215, MxA" ENSG00000157601 "MX dynamin like GTPase 1" P20591 21 41420020-41470071 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 123.7" "Cell type enhanced" "Detected in many" "Adipocytes: 107.4;dendritic cells: 122.5;Extravillous trophoblasts: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA030917, HPA030918, HPA049724" Approved Approved Supported "Nuclear membrane,Cytosol" No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "Nuclear membrane, Cytosol" "HPA030917: AB_10602010, HPA030918: , HPA049724: AB_2680862" "unprognostic (3.62e-1)" "unprognostic (6.84e-2)" "unprognostic (3.41e-2)" "unprognostic (2.55e-2)" "unprognostic (3.97e-1)" "unprognostic (2.27e-1)" "unprognostic (1.35e-3)" "unprognostic (5.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (6.88e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (9.95e-2)" "unprognostic (8.10e-2)" "unprognostic (3.24e-1)" "unprognostic (1.81e-1)" NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469679-23509862 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" 4 "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: AB_1079483" "unprognostic (2.63e-3)" "unprognostic (7.65e-2)" "unprognostic (2.84e-1)" "unprognostic (4.16e-3)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (8.87e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (3.87e-3)" "unprognostic (7.10e-2)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (9.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-1)" NSUN5 "FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL" ENSG00000130305 "NOP2/Sun RNA methyltransferase 5" Q96P11 7 73302516-73308826 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020536, HPA045590, HPA046867" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 44: Oocytes - Unknown function" "Nucleoplasm, Nucleoli" "HPA020536: AB_1858789, HPA045590: AB_2679376, HPA046867: AB_2679847" "unprognostic (3.94e-1)" "unprognostic (1.12e-1)" "unprognostic (3.79e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.92e-1)" "prognostic unfavorable (3.96e-4)" "unprognostic (3.54e-1)" "unprognostic (2.46e-1)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-2)" NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061910, HPA062595" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 16: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Mixed function" 9 Nucleoplasm Cytosol "HPA061910: AB_2684634, HPA062595: AB_2684801" "unprognostic (2.30e-1)" "unprognostic (5.10e-2)" "unprognostic (5.12e-3)" "unprognostic (2.52e-3)" "unprognostic (2.25e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.73e-7)" "unprognostic (3.46e-1)" "unprognostic (1.09e-2)" "unprognostic (9.93e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.03e-3)" "unprognostic (2.16e-1)" "unprognostic (9.10e-3)" "unprognostic (2.11e-1)" PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756253-60802086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm "Nuclear bodies, Cytosol" "CAB017795: , HPA035349: AB_2674583, HPA035350: AB_2674584" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659065-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 10 "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 7 "unprognostic (3.90e-2)" "unprognostic (4.86e-2)" "unprognostic (6.48e-3)" "unprognostic (1.86e-1)" "unprognostic (5.15e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.15e-2)" "unprognostic (1.19e-2)" "unprognostic (1.12e-3)" "unprognostic (4.83e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.74e-13)" "unprognostic (1.97e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (4.53e-2)" RLIM "MGC15161, NY-REN-43, RNF12" ENSG00000131263 "Ring finger protein, LIM domain interacting" Q9NVW2 X 74582976-74614624 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 40.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018895 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" 1 Nucleoplasm Cytosol "HPA018895: AB_1856323" "unprognostic (1.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.31e-3)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (8.98e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.25e-1)" "unprognostic (3.82e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.04e-4)" "unprognostic (1.20e-1)" RRS1 KIAA0112 ENSG00000179041 "Ribosome biogenesis regulator 1 homolog" Q15050 8 66429014-66430733 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055549, HPA060937" Approved Supported Nucleoli NA No "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 3 Nucleoli "HPA055549: AB_2682846, HPA060937: AB_2684390" "unprognostic (7.68e-2)" "unprognostic (1.02e-1)" "unprognostic (3.72e-2)" "unprognostic (5.25e-2)" "unprognostic (2.64e-1)" "unprognostic (3.84e-3)" "unprognostic (4.93e-3)" "unprognostic (2.82e-3)" "unprognostic (3.55e-1)" "unprognostic (1.96e-2)" "unprognostic (2.13e-2)" "unprognostic (1.01e-2)" "unprognostic (3.46e-2)" "unprognostic (8.61e-2)" "unprognostic (2.30e-1)" "unprognostic (5.29e-2)" "unprognostic (8.35e-3)" SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 83.6;Inhibitory neurons: 79.1;Oligodendrocyte precursor cells: 81.1;Oligodendrocytes: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA016737: AB_1857271" "unprognostic (5.01e-2)" "unprognostic (5.83e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (8.41e-3)" "unprognostic (9.08e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.55e-1)" "unprognostic (2.57e-2)" "unprognostic (7.72e-2)" "unprognostic (2.99e-2)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.20e-3)" UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359600-118399211 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 3 "Nuclear speckles" "HPA055035: AB_2682679, HPA064010: AB_2685174" "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" ZMIZ1 "FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10" ENSG00000108175 "Zinc finger MIZ-type containing 1" Q9ULJ6 10 79068966-79316519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 258.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045144, HPA071156" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA045144: AB_10962360, HPA071156: " "unprognostic (4.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.63e-1)" "unprognostic (5.59e-2)" "unprognostic (2.02e-1)" "unprognostic (2.86e-2)" "unprognostic (3.64e-3)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (1.16e-1)" "unprognostic (3.13e-2)" "unprognostic (7.90e-2)" "prognostic favorable (3.64e-7)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (8.22e-2)" "unprognostic (1.34e-2)" C9orf78 "CSU2, HCA59, HSPC220" ENSG00000136819 "Chromosome 9 open reading frame 78" Q9NZ63 9 129827290-129835863 "Predicted intracellular proteins" "Chromosome partition, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021216, HPA021232, HPA021242" Enhanced Enhanced Nucleoplasm No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Nucleoplasm "HPA021216: AB_1845836, HPA021232: AB_1845837, HPA021242: AB_1845838" "unprognostic (1.00e-1)" "unprognostic (4.23e-3)" "unprognostic (1.03e-2)" "unprognostic (1.83e-1)" "unprognostic (3.35e-2)" "unprognostic (7.03e-2)" "unprognostic (3.50e-2)" "unprognostic (6.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.26e-1)" "unprognostic (1.13e-2)" "unprognostic (1.43e-2)" "prognostic favorable (3.49e-7)" "unprognostic (5.34e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.0;Hepatocytes: 28.6;Proximal tubular cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.2;Hepatocytes: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 280000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.8" "Cell type enhanced" "Detected in many" "granulocytes: 72.9;Kupffer cells: 72.1;Macrophages: 72.3;monocytes: 238.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.2;eosinophil: 74.8;intermediate monocyte: 46.9;neutrophil: 55.8;non-classical monocyte: 90.2" "Group enriched" "Detected in many" 9 "granulocytes: 74.8;monocytes: 90.2" "Cancer enhanced" "Detected in many" "Leukemia: 7.7" "Lung - Neutrophil_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 18 Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.0;intestine: 11.7" "Cell type enhanced" "Detected in some" "Ductal cells: 11.6;Erythroid cells: 8.6;Pancreatic endocrine cells: 8.5;Plasma cells: 22.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung)" "HPA056980, HPA066719" Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 781.4;Spermatocytes: 308.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Monocytes - Innate immune response" 8 "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" BRME1 "C19orf57, MEIOK21, MGC11271" ENSG00000132016 "Break repair meiotic recombinase recruitment factor 1" Q0VDD7 19 13882348-13906452 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.3" "Group enriched" "Detected in many" 5 "Spermatocytes: 58.3;Spermatogonia: 17.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044012, HPA054615" Enhanced Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 19 Nucleoplasm "HPA044012: AB_10964782, HPA054615: AB_2682543" "unprognostic (1.71e-1)" "unprognostic (3.48e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (2.12e-1)" "prognostic favorable (5.14e-4)" "unprognostic (5.01e-2)" "unprognostic (2.30e-1)" "unprognostic (1.06e-1)" "unprognostic (1.36e-1)" "unprognostic (7.60e-2)" "unprognostic (4.43e-2)" "unprognostic (1.57e-4)" "unprognostic (1.21e-3)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (5.73e-2)" CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 92.9" "Cell type enhanced" "Detected in some" "dendritic cells: 55.9;Hofbauer cells: 135.8;Kupffer cells: 95.5;Macrophages: 76.0;monocytes: 132.3;NK-cells: 138.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 40.9;Myeloma: 12.0" "Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - T-cells" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" 6 "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.3;intestine: 80.3;smooth muscle: 91.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 49.0;Erythroid cells: 53.2;Extravillous trophoblasts: 72.4;Squamous epithelial cells: 72.9;Syncytiotrophoblasts: 195.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 303.4;Glandular and luminal cells: 312.5;Langerhans cells: 221.8;Mesothelial cells: 245.0;Prostatic glandular cells: 291.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 1400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" IL9R CD129 ENSG00000124334 "Interleukin 9 receptor" Q01113 X 155997696-156010817 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.3;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "granulocytes: 1.7;T-cells: 2.3" "Group enriched" "Detected in some" 4 "cervical cancer: 0.7;urothelial cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.5" "Group enriched" "Detected in many" 23 "B-cells: 1.9;granulocytes: 3.5;T-cells: 1.4" "Group enriched" "Detected in some" 7 "Leukemia: 18.3;lymphoma: 14.4" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063240, HPA064557" Approved "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "HPA063240: AB_2732700, HPA064557: AB_2732716" "unprognostic (1.07e-2)" "unprognostic (3.27e-3)" "unprognostic (9.52e-3)" "unprognostic (4.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.26e-4)" "unprognostic (8.94e-2)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (3.98e-8)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (4.07e-1)" "prognostic favorable (1.90e-7)" LARP7 "DKFZP564K112, HDCMA18P, PIP7S" ENSG00000174720 "La ribonucleoprotein 7, transcriptional regulator" Q4G0J3 4 112637077-112657696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" RNA-binding "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026842, HPA027930" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 4 "Nucleoplasm, Cytosol" "HPA026842: AB_10611116, HPA027930: AB_10601233" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (5.72e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (1.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 252.1;granulocytes: 842.8;monocytes: 363.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 48.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 107.0;Early spermatids: 121.8;Late spermatids: 170.5;Oocytes: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Late spermatids - Spermatogenesis" 1 Nucleoplasm "HPA041768: AB_10964172, HPA043600: AB_10961001" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.75e-3)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (9.32e-2)" "unprognostic (3.42e-1)" "unprognostic (6.08e-3)" "prognostic favorable (2.63e-4)" PCED1A "bA12M19.1, C20orf81, FAM113A, FLJ22376" ENSG00000132635 "PC-esterase domain containing 1A" Q9H1Q7 20 2835314-2841190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050816 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: Endometrial stromal cells - Transcription" 3 "Nucleoplasm, Cytosol" "HPA050816: AB_2681246" "unprognostic (3.20e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-3)" "unprognostic (1.90e-2)" "unprognostic (3.42e-1)" "unprognostic (6.91e-3)" "prognostic unfavorable (7.31e-4)" "unprognostic (1.00e-1)" "unprognostic (8.02e-2)" "unprognostic (2.99e-1)" "prognostic favorable (5.96e-5)" "unprognostic (1.03e-1)" "unprognostic (1.29e-2)" "unprognostic (4.10e-1)" "unprognostic (2.48e-1)" "unprognostic (7.30e-2)" "unprognostic (2.97e-3)" PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 279.0;Cardiomyocytes: 184.0;Excitatory neurons: 253.9;Inhibitory neurons: 193.0;Oligodendrocyte precursor cells: 556.6;Oligodendrocytes: 287.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.9;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;NK-cells: 10.3" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 432.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 1 Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" RSRC1 "BM-011, MGC12197, SFRS21, SRrp53" ENSG00000174891 "Arginine and serine rich coiled-coil 1" Q96IZ7 3 158105855-158545730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044792 Supported Approved "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" 2 "Nuclear speckles" "HPA044792: AB_10794502" "unprognostic (1.06e-2)" "unprognostic (8.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (7.40e-5)" "unprognostic (5.18e-1)" "unprognostic (1.17e-1)" "unprognostic (3.60e-3)" "unprognostic (2.91e-2)" "unprognostic (2.86e-2)" "unprognostic (5.71e-2)" "unprognostic (2.53e-3)" "unprognostic (8.84e-2)" "unprognostic (7.98e-3)" "unprognostic (3.48e-2)" "unprognostic (9.71e-2)" "unprognostic (2.71e-1)" "unprognostic (2.15e-1)" SLCO1B3-SLCO1B7 "LST-3TM12, OATP1B3-1B7" ENSG00000257046 "SLCO1B3-SLCO1B7 readthrough" 12 20815674-21090245 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 21.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.7;Gallbladder cancer: 3.0" HPA050892 Uncertain NA NA "Cluster 73: Breast - Lactation" "Cluster 57: Stomach & Colon cancer - Digestion" "HPA050892: AB_2681265" "unprognostic (2.74e-1)" "unprognostic (1.39e-3)" "unprognostic (3.44e-1)" TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487414-150507602 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" 11 "Nucleoplasm, Cytosol" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" TRIM60 "FLJ35882, RNF129, RNF33" ENSG00000176979 "Tripartite motif containing 60" Q495X7 4 165016458-165041749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "placenta: 1.4;testis: 1.5" "Group enriched" "Detected in some" 11 "Cytotrophoblasts: 5.2;Early spermatids: 4.1;Extravillous trophoblasts: 10.1;Oocytes: 11.0;Spermatocytes: 9.8;Spermatogonia: 7.0;Syncytiotrophoblasts: 4.8" "Cancer enriched" "Detected in single" 103 "testis cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.5" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA035809, HPA035810, HPA061496" Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Testis - Unknown function" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 Nucleoli "Nucleoplasm, Cytosol" "HPA035809: AB_2674794, HPA035810: AB_10601827, HPA061496: AB_2684540" "unprognostic (1.10e-1)" WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684651-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 26.5;retina: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Cone photoreceptor cells: 3.4;Early spermatids: 5.1;Late spermatids: 10.4;Microglial cells: 3.6;Rod photoreceptor cells: 8.2;Spermatocytes: 3.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 1 "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115174 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 387.8" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 39.0;Early spermatids: 11.5;Late spermatids: 14.9;Suprabasal keratinocytes: 33.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 1.6;head and neck cancer: 5.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 38.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.1;Extravillous trophoblasts: 26.5;Fibroblasts: 4.9;Inhibitory neurons: 4.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 18.6" "Kidney - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA055048 Enhanced "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA055048: AB_2682683" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 589.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 227.9;Alveolar cells type 2: 137.3;Suprabasal keratinocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" NOC2L "DKFZP564C186, NET15, NET7, NIR, PPP1R112" ENSG00000188976 "NOC2 like nucleolar associated transcriptional repressor" Q9Y3T9 1 944203-959309 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044258, HPA062195" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 310000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 2 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044258: AB_10961284, HPA062195: AB_2684707" "unprognostic (3.18e-2)" "unprognostic (5.84e-2)" "unprognostic (1.59e-1)" "unprognostic (9.54e-3)" "unprognostic (6.75e-2)" "unprognostic (2.31e-3)" "unprognostic (1.94e-3)" "unprognostic (1.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.17e-1)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (6.25e-2)" "unprognostic (3.44e-2)" "unprognostic (1.52e-1)" GINS3 "FLJ13912, PSF3" ENSG00000181938 "GINS complex subunit 3" Q9BRX5 16 58295080-58406147 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 24.2;Schwann cells: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041216, HPA048209" Uncertain Enhanced Nucleoplasm No No "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 54: Immune cells - T cell receptor" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Cell proliferation" 8 Nucleoplasm "HPA041216: AB_10794989, HPA048209: AB_2680314" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-3)" "unprognostic (6.34e-2)" "unprognostic (4.70e-2)" "unprognostic (2.82e-1)" "unprognostic (1.75e-4)" "unprognostic (7.76e-2)" "unprognostic (1.76e-3)" "unprognostic (7.19e-2)" "unprognostic (4.50e-2)" "unprognostic (2.67e-3)" "unprognostic (1.14e-7)" "unprognostic (9.76e-3)" "unprognostic (5.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.07e-2)" ACTR5 "Arp5, FLJ12785, INO80M" ENSG00000101442 "Actin related protein 5" Q9H9F9 20 38748460-38772520 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042676 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 8 "HPA042676: AB_2678110" "unprognostic (1.76e-1)" "unprognostic (4.89e-2)" "unprognostic (6.33e-2)" "unprognostic (8.45e-3)" "unprognostic (1.10e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (2.51e-1)" "unprognostic (2.93e-2)" "unprognostic (1.13e-1)" "unprognostic (5.00e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.83e-2)" "unprognostic (3.15e-1)" "unprognostic (2.01e-1)" "unprognostic (5.95e-2)" ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.8" "Cell type enhanced" "Detected in many" "Adipocytes: 159.7;Astrocytes: 79.9;Endometrial stromal cells: 165.1;Endothelial cells: 174.4;Mesothelial cells: 119.2;Smooth muscle cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 45.5;testis cancer: 37.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" Transport No NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 44.8" "Cell type enhanced" "Detected in many" "NK-cells: 187.5;Plasma cells: 76.1;T-cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.4" "Lung - T-cells, Testis - Sertoli cells, Thyroid - T-cells" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 1 "Nucleoplasm, Cytosol" "HPA001812: AB_1078175, HPA073637: " "prognostic favorable (4.78e-4)" "prognostic favorable (4.70e-4)" "unprognostic (8.18e-3)" "prognostic favorable (6.03e-5)" "unprognostic (2.37e-1)" "unprognostic (3.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.33e-1)" "unprognostic (4.23e-1)" "unprognostic (4.13e-3)" "unprognostic (9.13e-3)" "unprognostic (1.81e-1)" "prognostic unfavorable (8.66e-13)" "unprognostic (3.41e-2)" "unprognostic (5.83e-2)" "unprognostic (2.91e-2)" "prognostic favorable (6.30e-4)" APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140329-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 54.9;Endothelial cells: 64.6;Kupffer cells: 35.3;Lymphatic endothelial cells: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Testis - Endothelial cells" "Intracellular and membrane" Apolipoprotein NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 116.5" "Cell type enriched" "Detected in some" 71 "Hepatocytes: 272.3" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 2780000 23000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" CCL3L1 "CCL3L3, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 1" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;lung: 4.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 796.8;Kupffer cells: 154.6;Langerhans cells: 385.1;Macrophages: 500.2;monocytes: 206.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 11 "lymphoma: 2.3;Myeloma: 9.1" "Secreted to blood" Chemokine NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Myeloma - Immune response" "Cluster 58: Macrophages - Innate immune response" 4 "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "unprognostic (5.37e-2)" "unprognostic (1.46e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.36e-2)" "unprognostic (3.69e-1)" "unprognostic (5.75e-2)" "unprognostic (5.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.66e-1)" "unprognostic (9.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-2)" "unprognostic (8.58e-2)" CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No 1100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 15: Non-specific - Mixed function" 8 "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA018520: AB_1846204, HPA021051: AB_1846205, HPA029426: AB_10601796" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (8.78e-2)" "unprognostic (1.37e-1)" "unprognostic (3.09e-1)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (8.26e-2)" "unprognostic (3.50e-2)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.7;lymphoid tissue: 39.5" "Group enriched" "Detected in some" 5 "NK-cells: 9.8;Serous glandular cells: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1477.6" "Lineage enriched" "Detected in many" 62 "granulocytes: 1477.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 3 "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" DAZ2 "MGC126442, pDP1678" ENSG00000205944 "Deleted in azoospermia 2" Q13117 Y 23219447-23291356 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "stomach 1: 5.2;testis: 2.9" "Cell type enriched" "Detected in single" 23 "Gastric mucus-secreting cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.4;Neuroblastoma: 5.5" HPA047113 Approved NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA047113: AB_2679936" DEFB118 "C20orf63, DEFB-18, dJ1018D12.3, ESC42" ENSG00000131068 "Defensin beta 118" Q96PH6 20 31368601-31373923 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9676 "epididymis: 967.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042634 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" 2 "HPA042634: AB_10797505" "unprognostic (3.24e-1)" DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 1870.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.6;Early spermatids: 53.2;Late spermatids: 80.2;Rod photoreceptor cells: 118.8;Sertoli cells: 424.3" "Cancer enriched" "Detected in single" 67 "testis cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 1.9" HPA043059 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 66: Photoreceptor cells - Visual perception" "HPA043059: AB_10797025" "unprognostic (2.03e-1)" DRAM1 "DRAM, FLJ11259" ENSG00000136048 "DNA damage regulated autophagy modulator 1" Q8N682 12 101877580-102012130 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 91.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 187.5;Early spermatids: 142.4;Late spermatids: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" 6 "unprognostic (8.82e-2)" "unprognostic (1.80e-1)" "unprognostic (7.19e-2)" "prognostic favorable (6.52e-8)" "unprognostic (1.15e-2)" "unprognostic (2.35e-3)" "unprognostic (1.29e-3)" "unprognostic (1.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-3)" "unprognostic (5.02e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" FAM47E "FLJ42946, LOC100129583" ENSG00000189157 "Family with sequence similarity 47 member E" Q6ZV65 4 76214040-76283783 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Ciliated cells: 48.7;Early spermatids: 61.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053331 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-4)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-8)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-2)" "unprognostic (3.01e-2)" GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 38.4" "Cell type enhanced" "Detected in many" "Adipocytes: 8.5;Distal enterocytes: 10.3;Hepatocytes: 22.9;Kupffer cells: 17.8;Muller glia cells: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.7;myeloid DC: 5.8" "Group enriched" "Detected in many" 23 "dendritic cells: 5.8;monocytes: 2.9" "Cancer enhanced" "Detected in many" "lymphoma: 11.1" "Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" GTPBP10 "DKFZP686A10121, FLJ38242, OBGH2" ENSG00000105793 "GTP binding protein 10" A4D1E9 7 90335223-90391453 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021076 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 3 "HPA021076: AB_1850411" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-2)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (3.56e-1)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (5.38e-2)" "unprognostic (2.32e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.76e-5)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (2.72e-3)" HMCES "C3orf37, DC12, SRAPD1" ENSG00000183624 "5-hydroxymethylcytosine binding, ES cell specific" Q96FZ2 3 129278828-129306186 "Predicted intracellular proteins" "DNA damage" "DNA-binding, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 117.7;Spermatocytes: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044968 Enhanced Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" Nucleoplasm "HPA044968: AB_2679160" "unprognostic (9.18e-3)" "unprognostic (1.11e-3)" "unprognostic (4.16e-2)" "unprognostic (2.80e-2)" "unprognostic (2.93e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (3.00e-1)" "unprognostic (4.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-2)" "unprognostic (1.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (9.08e-3)" IL6R "CD126, gp80, IL-1Ra, IL-6R, IL6RA" ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.9;skeletal muscle: 90.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 86.2;Langerhans cells: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 83.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 24800000 35000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 3 "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (3.27e-1)" "unprognostic (6.42e-2)" "prognostic favorable (1.65e-4)" "unprognostic (7.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 56: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" KIR2DL4 "103AS, 15.212, CD158D" ENSG00000189013 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4" Q99706 19 54803610-54814517 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 3.9" "Group enriched" "Detected in some" 16 "NK-cells: 35.0;T-cells: 23.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 80 "NK-cell: 8.0" "Lineage enriched" "Detected in single" 80 "NK-cells: 8.0" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: T-cells - T-cell receptor" 6 "unprognostic (1.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.84e-2)" "unprognostic (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (5.95e-4)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.92e-5)" "unprognostic (5.15e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.53e-8)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (6.10e-4)" "unprognostic (3.59e-3)" LIPT1 "MGC12290, MGC13378" ENSG00000144182 "Lipoyltransferase 1" Q9Y234 2 99154955-99163157 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 45.9;Oocytes: 47.8;Spermatocytes: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA034802 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 4 "HPA034802: AB_10669851" "unprognostic (1.13e-2)" "unprognostic (7.21e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-2)" "unprognostic (7.46e-2)" "unprognostic (6.48e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.70e-4)" "unprognostic (1.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.32e-3)" "unprognostic (1.72e-1)" "unprognostic (4.92e-2)" "unprognostic (3.16e-1)" "prognostic favorable (9.60e-8)" LSM1 "CASM, YJL124C" ENSG00000175324 "LSM1 homolog, mRNA degradation associated" O15116 8 38163335-38176730 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024601 Approved "Cytosol,Cytoplasmic bodies" NA NA 22000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 16 "Cytoplasmic bodies" Cytosol "HPA024601: AB_1853379" "unprognostic (1.19e-2)" "unprognostic (7.21e-2)" "unprognostic (1.94e-2)" "unprognostic (9.59e-2)" "unprognostic (7.26e-2)" "unprognostic (1.69e-1)" "unprognostic (2.08e-3)" "unprognostic (2.18e-2)" "unprognostic (1.95e-2)" "unprognostic (2.48e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (3.47e-2)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (8.75e-2)" "unprognostic (2.97e-1)" METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase 1, tRNA methylguanosine" Q9UBP6 12 57768471-57772119 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm "HPA020914: AB_1853830, HPA050450: AB_2681130" "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" N6AMT1 "C21orf127, HEMK2, KMT9, MTQ2, N6AMT, PRED28, PrmC" ENSG00000156239 "N-6 adenine-specific DNA methyltransferase 1" Q9Y5N5 21 28872191-28885371 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034133, CAB034135, HPA059242" Approved Approved Nucleoplasm,Centrosome Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm Centrosome "CAB034133: AB_2147189, CAB034135: AB_2250945, HPA059242: AB_2683957" "unprognostic (2.20e-2)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (7.46e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.64e-1)" "unprognostic (1.04e-1)" "unprognostic (1.94e-2)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (5.24e-2)" "unprognostic (6.99e-2)" "unprognostic (5.43e-2)" "unprognostic (5.51e-3)" NAT10 "FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43" ENSG00000135372 "N-acetyltransferase 10" Q9H0A0 11 34105617-34147670 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035546, HPA057576, HPA071628" Approved Enhanced Nucleoli,Midbody Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 2 Nucleoli Midbody "CAB035546: , HPA057576: AB_2683475, HPA071628: AB_2686426" "unprognostic (3.04e-1)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (1.07e-4)" "prognostic unfavorable (9.61e-8)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.83e-5)" "unprognostic (1.24e-1)" "unprognostic (7.18e-2)" "unprognostic (9.55e-2)" "unprognostic (8.69e-2)" NBR1 "1A1-3B, CA125, KIAA0049, M17S2" ENSG00000188554 "NBR1 autophagy cargo receptor" Q14596 17 43170481-43211689 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 897.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022944, HPA022999, HPA023999" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 13 Vesicles "Nucleoplasm, Nuclear bodies" "HPA022944: AB_2671001, HPA022999: AB_1859532, HPA023999: AB_1859533" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "prognostic favorable (2.00e-5)" "unprognostic (1.65e-1)" "unprognostic (4.88e-2)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 135.8;Hofbauer cells: 98.4;Oocytes: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" 20 "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" NHEJ1 "Cernunnos, FLJ12610, XLF" ENSG00000187736 "Non-homologous end joining factor 1" Q9H9Q4 2 219069355-219160869 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 30.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012334, HPA043869" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 16: Intestinal goblet cells - Mucin production" 3 Nucleoplasm "Nucleoli fibrillar center" "CAB012334: , HPA043869: AB_2678707" "unprognostic (5.66e-2)" "unprognostic (3.01e-2)" "unprognostic (3.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (5.92e-2)" "unprognostic (5.16e-2)" "unprognostic (6.04e-2)" "unprognostic (3.51e-2)" "unprognostic (6.87e-2)" "unprognostic (1.58e-3)" "unprognostic (4.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (8.29e-2)" NICN1 MGC12936 ENSG00000145029 "Nicolin 1, tubulin polyglutamylase complex subunit" Q9BSH3 3 49422333-49429326 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Astrocytes: 4.6;Excitatory neurons: 4.2;Gastric mucus-secreting cells: 1.8;Inhibitory neurons: 4.7;Microglial cells: 1.8;Oligodendrocyte precursor cells: 2.8;Oligodendrocytes: 2.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 20.4" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058014 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Astrocytes - Unknown function" 9 Nucleoplasm "HPA058014: AB_2683579" "unprognostic (4.10e-2)" "unprognostic (1.08e-2)" "unprognostic (7.31e-2)" "unprognostic (1.33e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-2)" "unprognostic (1.31e-2)" "unprognostic (4.50e-3)" "unprognostic (1.04e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.11e-4)" "unprognostic (2.46e-1)" "prognostic favorable (8.81e-7)" "unprognostic (3.11e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-2)" "unprognostic (2.96e-2)" P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028013 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 25.1;tongue: 11.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Excitatory neurons: 8.6;Horizontal cells: 10.7;Inhibitory neurons: 7.6;Oligodendrocyte precursor cells: 4.7;Skeletal myocytes: 5.9" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.3" "Liver - Hepatic stellate cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" PBX2 "G17, HOX12, PBX2MHC" ENSG00000204304 "PBX homeobox 2" P40425 6 32184733-32190202 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061478 Supported Approved Nucleoplasm NA NA "Cluster 66: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" 19 Nucleoplasm "HPA061478: AB_2684535" "unprognostic (9.73e-3)" "unprognostic (2.16e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (8.90e-5)" "unprognostic (4.98e-1)" "unprognostic (2.68e-2)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.81e-2)" "prognostic favorable (6.84e-4)" "unprognostic (3.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.06e-1)" "unprognostic (2.52e-2)" "unprognostic (2.27e-1)" PHF20 "C20orf104, dJ1121G12.1, TDRD20A" ENSG00000025293 "PHD finger protein 20" Q9BVI0 20 35771974-35950370 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.1;Late spermatids: 699.1;monocytes: 400.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029619, HPA029620, HPA029621" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 24 "Nucleoplasm, Nuclear membrane" Cytosol "HPA029619: AB_10600090, HPA029620: AB_10601110, HPA029621: AB_10602201" "unprognostic (1.21e-3)" "unprognostic (7.30e-2)" "unprognostic (3.20e-2)" "unprognostic (2.35e-3)" "unprognostic (1.36e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.76e-1)" "unprognostic (2.17e-1)" "unprognostic (2.64e-2)" "unprognostic (4.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.92e-2)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (7.23e-2)" "unprognostic (1.01e-2)" PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 509.1;Suprabasal keratinocytes: 542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 58 "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" HPA003656 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 5 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA049700: AB_2680856" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (7.20e-2)" POLR1B "FLJ10816, FLJ21921, RPA135, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112579818 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 18: Early spermatids - Unknown function" 2 "Nucleoli fibrillar center" Cytosol "HPA037528: AB_10671627" "unprognostic (1.66e-1)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (6.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" 15 "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" PRR14 MGC3121 ENSG00000156858 "Proline rich 14" Q9BWN1 16 30650717-30656413 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052022, HPA060265, HPA075914" Uncertain Enhanced Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 2 Nucleoplasm "HPA052022: AB_2681698, HPA060265: AB_2684236, HPA075914: " "unprognostic (1.57e-1)" "prognostic favorable (8.19e-5)" "unprognostic (3.74e-3)" "unprognostic (1.42e-2)" "unprognostic (5.18e-2)" "unprognostic (5.44e-2)" "unprognostic (5.28e-3)" "unprognostic (1.42e-2)" "unprognostic (5.75e-2)" "unprognostic (1.82e-2)" "unprognostic (1.61e-2)" "unprognostic (5.69e-2)" "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (4.54e-1)" "unprognostic (9.10e-2)" "unprognostic (2.31e-3)" PSMD7 "MOV34, P40, Rpn8, S12" ENSG00000103035 "Proteasome 26S subunit, non-ATPase 7" P51665 16 74296814-74306288 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 699.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019379, HPA049824, HPA056069" Enhanced Enhanced Nucleoplasm NA NA 190000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 15: Non-specific - Mixed function" 19 Nucleoplasm "CAB019379: , HPA049824: AB_2680899, HPA056069: AB_2683025" "unprognostic (4.75e-3)" "unprognostic (1.30e-1)" "unprognostic (2.84e-2)" "unprognostic (6.95e-2)" "unprognostic (7.62e-2)" "prognostic unfavorable (6.64e-5)" "prognostic unfavorable (7.71e-6)" "unprognostic (1.97e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (9.34e-3)" "unprognostic (1.34e-2)" "unprognostic (2.52e-2)" "unprognostic (5.06e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.86e-2)" PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374563-38383850 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 672.1" "Cell type enhanced" "Detected in all" "Late spermatids: 1159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 6 Cytosol "Nuclear speckles" "CAB021101: AB_10061018, HPA006702: AB_1079710" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.59e-1)" "unprognostic (5.54e-3)" "unprognostic (1.94e-3)" "unprognostic (5.03e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (4.61e-1)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.28e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.84e-2)" PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.2;tongue: 14.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.4;Distal tubular cells: 27.7;Early spermatids: 21.1;Late spermatids: 33.5;Proximal tubular cells: 13.8;Spermatocytes: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Testis - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 13: Spermatids - Transcription" "Centriolar satellite" "HPA043337: AB_2678436, HPA046896: , HPA048310: AB_2680350, HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" RAI1 "DKFZP434A139, KIAA1820, MGC12824, SMCR, SMS" ENSG00000108557 "Retinoic acid induced 1" Q7Z5J4 17 17681458-17811453 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023898, HPA054906" Approved Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 Nucleoplasm "HPA023898: AB_10971089, HPA054906: AB_2682637" "unprognostic (7.57e-2)" "unprognostic (3.83e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (1.94e-2)" "unprognostic (3.85e-2)" "unprognostic (3.02e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (2.61e-2)" "unprognostic (5.29e-2)" "unprognostic (4.20e-2)" "unprognostic (6.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-2)" "unprognostic (8.28e-2)" RBM45 "DRB1, FLJ44612" ENSG00000155636 "RNA binding motif protein 45" Q8IUH3 2 178112424-178139011 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020448 Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Non-specific - Transcription" 8 Nucleoplasm "HPA020448: AB_1856133" "unprognostic (3.11e-2)" "unprognostic (1.91e-1)" "unprognostic (6.56e-2)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (5.74e-9)" "unprognostic (1.66e-1)" "unprognostic (4.25e-2)" "unprognostic (2.71e-2)" "unprognostic (2.42e-1)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.34e-9)" "unprognostic (3.26e-1)" "unprognostic (2.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.94e-1)" REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA036022: AB_10610417" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (7.50e-3)" "unprognostic (5.42e-2)" "unprognostic (7.00e-3)" "unprognostic (1.52e-2)" "unprognostic (6.88e-3)" "unprognostic (6.68e-2)" "unprognostic (6.59e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.40e-2)" "prognostic favorable (5.56e-4)" "prognostic favorable (1.61e-4)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "prognostic favorable (6.41e-4)" SLF1 "ANKRD32, BRCTD1, BRCTx, DKFZp564C0469, DKFZp761C121" ENSG00000133302 "SMC5-SMC6 complex localization factor 1" Q9BQI6 5 94618669-94739436 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.3;Spermatocytes: 146.5;Spermatogonia: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040793, HPA054213" Uncertain Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA040793: AB_10796560, HPA054213: AB_2682419" "unprognostic (7.56e-2)" "unprognostic (1.45e-2)" "unprognostic (2.44e-3)" "unprognostic (1.02e-1)" "unprognostic (1.68e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-5)" "unprognostic (1.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (6.57e-6)" "unprognostic (3.27e-2)" "unprognostic (2.83e-1)" "unprognostic (1.77e-1)" "unprognostic (8.32e-2)" SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.7;testis: 10.3" "Cell type enhanced" "Detected in many" "Spermatocytes: 17.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049421, HPA066238" Approved Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 57: Platelets - Hemostasis" 12 Nucleoplasm "Cell Junctions, Cytosol" "HPA049421: AB_2680759, HPA066238: AB_2685642" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (6.08e-3)" "unprognostic (8.28e-5)" "unprognostic (6.52e-2)" "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" "unprognostic (8.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (5.74e-2)" SNU13 "15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1" ENSG00000100138 "Small nuclear ribonucleoprotein 13" P55769 22 41673933-41690504 "Predicted intracellular proteins, Ribosomal proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA029199 Uncertain NA NA 28000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 3 "HPA029199: AB_10601041" "unprognostic (3.02e-1)" "unprognostic (4.82e-2)" "unprognostic (8.58e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (4.54e-2)" "unprognostic (1.94e-3)" "unprognostic (2.43e-1)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (3.46e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" "unprognostic (1.43e-1)" SPRTN "C1orf124, DKFZP547N043, DVC1, Spartan" ENSG00000010072 "SprT-like N-terminal domain" Q9H040 1 231337104-231355023 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025073 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA025073: AB_1847695" "unprognostic (2.63e-1)" "unprognostic (5.41e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (2.00e-1)" "unprognostic (5.69e-3)" "unprognostic (1.72e-1)" "unprognostic (1.33e-2)" "unprognostic (4.75e-3)" "unprognostic (1.26e-1)" "unprognostic (3.25e-1)" "unprognostic (7.51e-3)" "unprognostic (1.19e-1)" "unprognostic (3.21e-2)" "unprognostic (3.60e-2)" "unprognostic (5.35e-2)" SUN1 "FLJ12407, KIAA0810, UNC84A" ENSG00000164828 "Sad1 and UNC84 domain containing 1" O94901 7 816615-896435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Meiosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 329.3;Late spermatids: 583.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008346, HPA008461" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 4 "Nuclear membrane" "HPA008346: AB_1080462, HPA008461: AB_1080461" "unprognostic (2.70e-2)" "unprognostic (1.51e-2)" "unprognostic (1.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.25e-1)" "unprognostic (2.57e-3)" "unprognostic (1.82e-1)" "unprognostic (1.67e-1)" "unprognostic (4.57e-2)" "unprognostic (3.32e-2)" "unprognostic (1.69e-1)" "unprognostic (8.10e-2)" "unprognostic (1.08e-2)" "unprognostic (1.47e-2)" "unprognostic (4.63e-2)" "unprognostic (1.34e-1)" "unprognostic (9.33e-2)" THOC2 "CXorf3, dJ506G2.1, MRX12, MRX35, THO2" ENSG00000125676 "THO complex subunit 2" Q8NI27 X 123600561-123733056 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047921 Supported Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA047921: AB_10960388" "unprognostic (2.12e-2)" "unprognostic (5.64e-2)" "unprognostic (3.49e-1)" "unprognostic (3.74e-2)" "unprognostic (2.22e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.77e-5)" "unprognostic (1.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (6.29e-2)" "unprognostic (4.27e-3)" "unprognostic (6.43e-3)" "unprognostic (1.05e-1)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 64.4" "Group enriched" "Detected in some" 16 "Late spermatids: 298.6;Proximal enterocytes: 185.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 12000000 "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm,Cytosol NA NA 14000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 9 Nucleoplasm Cytosol "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 220000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 7 "Nucleoplasm, Vesicles, Cytosol" "HPA030968: AB_10602585, HPA030969: AB_2673679" "prognostic unfavorable (7.02e-4)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.17e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.83e-2)" "unprognostic (3.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.96e-1)" "unprognostic (3.24e-1)" ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 50.2" "Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 Nucleoplasm "HPA021554: AB_1858937, HPA050569: AB_2681179" "unprognostic (7.97e-2)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (6.67e-2)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (4.86e-1)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.52e-4)" "unprognostic (4.65e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.63e-2)" ZDHHC8 "DHHC8, KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Non-specific - DNA binding" Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 14.9;Cone photoreceptor cells: 17.0;Rod photoreceptor cells: 28.1;Spermatocytes: 14.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA063685 Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Ciliated cells - Cilium assembly" 23 Mitochondria "HPA063685: AB_2685090" "unprognostic (5.59e-4)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-4)" "unprognostic (6.02e-3)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (4.84e-2)" "unprognostic (8.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.04e-6)" "unprognostic (3.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.87e-2)" CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Ribosome" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: AB_2683654" "unprognostic (4.35e-1)" "unprognostic (6.41e-3)" "unprognostic (4.31e-3)" "unprognostic (7.85e-2)" "unprognostic (6.31e-2)" "unprognostic (3.85e-3)" "unprognostic (6.40e-2)" "prognostic favorable (9.67e-4)" "unprognostic (3.22e-2)" "unprognostic (7.13e-2)" "unprognostic (8.35e-2)" "unprognostic (4.32e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 49.9;Oocytes: 61.8;Spermatocytes: 118.2;Spermatogonia: 62.9;Syncytiotrophoblasts: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 41: Basophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 8 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" NDEL1 "MITAP1, NDE1L1, NDE2, NUDEL" ENSG00000166579 "NudE neurodevelopment protein 1 like 1" Q9GZM8 17 8413131-8490411 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 170.2;Late spermatids: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017916 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 29: Monocytes - Innate immune response" 60 "HPA017916: AB_1854337" "unprognostic (6.34e-2)" "unprognostic (4.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-3)" "unprognostic (6.98e-3)" "unprognostic (1.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.77e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (4.66e-2)" "unprognostic (5.89e-2)" "unprognostic (6.73e-3)" "unprognostic (8.82e-2)" "unprognostic (1.01e-1)" "unprognostic (7.63e-3)" DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: Endometrial stromal cells - Transcription" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" NUMA1 NUMA ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 6 Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.7" "Cell type enhanced" "Detected in many" "Plasma cells: 13.9;Squamous epithelial cells: 15.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 77: Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" 6 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 308.5;dendritic cells: 539.1;granulocytes: 438.3;Langerhans cells: 496.3;Macrophages: 221.3;monocytes: 285.1;Schwann cells: 282.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 7.3;skin cancer: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 30 "HPA043360: AB_10961186" "prognostic favorable (5.97e-4)" "unprognostic (6.92e-3)" "unprognostic (5.34e-2)" "unprognostic (2.78e-3)" "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (2.89e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-3)" "unprognostic (1.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-3)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" PMF1 ENSG00000160783 "Polyamine modulated factor 1" Q6P1K2 1 156212993-156240042 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA034583, HPA071854" Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 13 Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: AB_2674234, HPA071854: AB_2686459" "unprognostic (1.17e-2)" "unprognostic (3.76e-3)" "unprognostic (2.58e-2)" "unprognostic (5.67e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (6.44e-2)" "unprognostic (1.32e-1)" "unprognostic (3.13e-1)" "unprognostic (1.26e-2)" "unprognostic (1.41e-2)" "unprognostic (9.29e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-2)" CENPT "C16orf56, CENP-T, FLJ13111" ENSG00000102901 "Centromere protein T" Q96BT3 16 67828157-67847811 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 83.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041220, HPA058036" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 21: Testis - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 57: Platelets - Hemostasis" 3 "Nuclear bodies" Nucleoplasm "HPA041220: AB_2677367, HPA058036: AB_2683585" "unprognostic (9.84e-2)" "unprognostic (2.86e-2)" "unprognostic (3.04e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-2)" "unprognostic (6.66e-3)" "unprognostic (1.18e-2)" "unprognostic (2.81e-1)" "unprognostic (8.04e-2)" "unprognostic (3.15e-2)" "prognostic favorable (2.96e-4)" "unprognostic (6.64e-3)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (9.74e-3)" BANF2 "BAF-L, BAF2, BAFL, C20orf179, dJ803K15.1" ENSG00000125888 "BANF family member 2" Q9H503 20 17693672-17735871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 107.2" "Cell type enriched" "Detected in some" 4 "Late spermatids: 2796.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042635 Approved NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" "HPA042635: AB_10795707" "unprognostic (2.08e-1)" "unprognostic (9.15e-2)" "unprognostic (6.42e-3)" "unprognostic (1.13e-1)" "unprognostic (1.63e-2)" "unprognostic (3.42e-1)" "unprognostic (3.18e-1)" BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.4;lymphoid tissue: 4.4;testis: 3.0" "Cell type enhanced" "Detected in many" "dendritic cells: 46.9;Oocytes: 46.3;Spermatocytes: 124.1;Spermatogonia: 72.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 19: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 11 Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" C15orf48 "COXFA4L3, MIR147BHG, MISTRAV, MOCCI, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 893.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4361.0;Enteroendocrine cells: 1468.6;Exocrine glandular cells: 2025.4;Intestinal goblet cells: 1372.4;Langerhans cells: 2561.4;Paneth cells: 2158.2;Proximal enterocytes: 3050.5;Undifferentiated cells: 1467.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 6.3" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 606.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.5;Erythroid cells: 66.4;Extravillous trophoblasts: 97.7;Spermatocytes: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Cell proliferation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" MEAF6 "C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91" ENSG00000163875 "MYST/Esa1 associated factor 6" Q9HAF1 1 37489993-37514766 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029599 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 40: Prostatic glandular cells - Transcription" 10 "Nuclear bodies" Nucleoplasm "HPA029599: AB_10599996" "unprognostic (4.95e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.41e-3)" "unprognostic (4.36e-2)" "unprognostic (3.16e-2)" "unprognostic (9.75e-3)" "unprognostic (2.87e-3)" "unprognostic (4.91e-2)" "unprognostic (2.68e-3)" "unprognostic (3.57e-2)" "unprognostic (4.77e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (3.93e-2)" "unprognostic (5.12e-3)" "unprognostic (2.19e-1)" NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 64.9;Oligodendrocytes: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 22.2;monocytes: 11.9;NK-cells: 8.6" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 3 "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" HDAC8 "HDACL1, KDAC8, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573101 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease variant, FDA approved drug targets, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.6;Excitatory neurons: 180.5;Inhibitory neurons: 183.4;Microglial cells: 128.8;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048560 Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 8: Neurons - Neuronal signaling" "HPA048560: AB_2680442" "unprognostic (1.42e-1)" "unprognostic (6.62e-3)" "unprognostic (3.20e-2)" "unprognostic (9.24e-3)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (2.81e-2)" "unprognostic (3.17e-2)" "unprognostic (9.68e-2)" "unprognostic (8.42e-2)" "unprognostic (2.33e-3)" "unprognostic (9.10e-2)" "unprognostic (7.15e-3)" "unprognostic (2.12e-3)" MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.8;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.9;Erythroid cells: 71.0;Extravillous trophoblasts: 24.4;Plasma cells: 24.8;Spermatogonia: 24.7;Syncytiotrophoblasts: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 52: Non-specific - Cell proliferation" 47 Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.2;dendritic cells: 47.7;Erythroid cells: 51.8;Spermatogonia: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm NA Yes 33000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cell proliferation" 16 Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 235.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 4 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 2 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: AB_2142390, CAB075728: AB_2665734, CAB075729: AB_2665735, HPA035735: AB_2674758, HPA035736: AB_2674759" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (1.21e-1)" "unprognostic (4.15e-3)" "prognostic unfavorable (2.92e-6)" "unprognostic (7.74e-3)" "unprognostic (4.63e-2)" "unprognostic (3.21e-2)" "unprognostic (6.02e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (5.01e-11)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" CTC1 "AAF132, C17orf68, FLJ22170" ENSG00000178971 "CST telomere replication complex component 1" Q2NKJ3 17 8224815-8248058 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052436 Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 49: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA052436: " "unprognostic (6.47e-2)" "unprognostic (1.06e-2)" "unprognostic (6.16e-3)" "unprognostic (2.81e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-3)" "unprognostic (3.96e-1)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "prognostic favorable (6.49e-5)" "unprognostic (2.89e-3)" "unprognostic (3.24e-1)" "unprognostic (5.76e-2)" "unprognostic (1.47e-1)" "unprognostic (1.77e-2)" "unprognostic (1.66e-2)" HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983686 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm NA NA 27000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 26 Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" PMF1-BGLAP ENSG00000260238 "PMF1-BGLAP readthrough" 1 156212982-156243332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.2;Sertoli cells: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA034583, HPA071854" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: AB_2674234, HPA071854: AB_2686459" "unprognostic (8.15e-2)" "unprognostic (1.80e-1)" "unprognostic (8.56e-4)" "unprognostic (1.65e-2)" "unprognostic (4.01e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.66e-2)" "unprognostic (1.28e-1)" "unprognostic (8.52e-3)" "unprognostic (1.85e-4)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.12e-1)" "unprognostic (2.37e-1)" "unprognostic (5.31e-3)" "unprognostic (2.36e-1)" SS18 "SMARCL1, SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 73: B-cells - B-cell function" 2 Nucleoplasm Cytosol "HPA055741: AB_2682901, HPA059539: AB_2684055" "unprognostic (2.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.95e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "unprognostic (4.59e-2)" "unprognostic (1.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.40e-2)" "unprognostic (1.30e-1)" NUP43 "bA350J20.1, FLJ13287" ENSG00000120253 "Nucleoporin 43" Q8NFH3 6 149724315-149749665 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 81.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027126, HPA027291, HPA028500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 11 "Nucleoplasm, Nuclear speckles" Cytosol "HPA027126: AB_10599301, HPA027291: AB_10601851, HPA028500: AB_10602287" "prognostic unfavorable (2.08e-4)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.45e-3)" "unprognostic (2.29e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (7.13e-7)" "unprognostic (5.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-2)" "unprognostic (6.25e-3)" "unprognostic (2.02e-1)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" TOP2B "top2beta, TOPIIB" ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597978-25664909 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Nucleoplasm "CAB004601: AB_628384, HPA024120: AB_1858191, HPA050441: AB_2681127" "unprognostic (2.90e-2)" "unprognostic (5.17e-2)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (7.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" ZW10 KNTC1AP ENSG00000086827 "Zw10 kinetochore protein" O43264 11 113733187-113773735 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, ER-Golgi transport, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011565, HPA051253, HPA055410" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 3 "Endoplasmic reticulum, Cytosol" "CAB011565: AB_779030, HPA051253: AB_2681408, HPA055410: AB_2682809" "unprognostic (4.33e-3)" "unprognostic (6.65e-2)" "prognostic favorable (2.70e-4)" "unprognostic (3.12e-1)" "unprognostic (5.51e-2)" "unprognostic (6.52e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (7.44e-2)" "unprognostic (8.01e-3)" "unprognostic (5.91e-2)" "unprognostic (1.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.57e-3)" "unprognostic (6.00e-2)" "unprognostic (8.73e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-3)" CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 79.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 436.0;Distal tubular cells: 627.0;Proximal enterocytes: 543.8;Proximal tubular cells: 725.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774405-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 549.3" "Cell type enhanced" "Detected in many" "Early spermatids: 2930.3;Late spermatids: 4576.0;Spermatocytes: 1193.8" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 21: Testis - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788624-49835026 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 9 Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "skeletal muscle: 280.7;tongue: 170.7" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 108.3" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Fibroblasts - ECM organization" "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 48.3;Spermatogonia: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 40: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 10 Nucleoplasm Cytosol "CAB004375: AB_675487, HPA046524: AB_2679684" "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" SLC9A7 "NHE-7, NHE7" ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "dendritic cells: 53.1;Excitatory neurons: 41.9;Inhibitory neurons: 64.0;Oligodendrocyte precursor cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Vesicles "HPA048938: AB_2680565, HPA075385: AB_2686747" "unprognostic (2.77e-1)" "unprognostic (4.68e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.58e-4)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.16e-2)" "unprognostic (2.73e-3)" "unprognostic (5.26e-3)" "unprognostic (1.28e-2)" "unprognostic (9.25e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (7.20e-2)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" SYCE2 CESC1 ENSG00000161860 "Synaptonemal complex central element protein 2" Q6PIF2 19 12898786-12919293 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 25.9" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 223.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.7" "Lineage enhanced" "Detected in single" "NK-cells: 2.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042080, HPA062919" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 9 Nucleoplasm "HPA042080: AB_10794411, HPA062919: AB_2684905" "unprognostic (3.00e-1)" "prognostic favorable (3.85e-5)" "unprognostic (9.99e-3)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.75e-1)" "unprognostic (3.48e-2)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (1.78e-1)" "unprognostic (8.28e-3)" "unprognostic (1.30e-2)" "unprognostic (8.39e-4)" "unprognostic (1.79e-10)" "unprognostic (7.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.09e-1)" "unprognostic (7.87e-5)" TEN1 "C17orf106, FLJ39785" ENSG00000257949 "TEN1 subunit of CST complex" Q86WV5 17 75979240-76000586 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065069 Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Stomach - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Non-specific - Transcription" 14 Nucleoplasm "HPA065069: AB_2685418" "unprognostic (1.61e-1)" "unprognostic (1.16e-1)" "unprognostic (3.34e-2)" "unprognostic (1.07e-1)" "unprognostic (3.02e-2)" "unprognostic (3.07e-3)" "unprognostic (1.33e-3)" "unprognostic (2.95e-1)" "unprognostic (2.85e-2)" "unprognostic (9.03e-2)" "unprognostic (8.61e-3)" "unprognostic (3.17e-2)" "unprognostic (1.64e-2)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (2.94e-1)" "unprognostic (2.85e-4)" TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 161.7;skeletal muscle: 887.9;tongue: 355.2" "Group enriched" "Detected in many" 80 "Cardiomyocytes: 42687.1;Skeletal myocytes: 19073.0" "Cancer enriched" "Detected in single" 4 "head and neck cancer: 1.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Sarcoma: 3.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 16000000 "Cluster 24: Non-specific - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" NSMCE4A "bA500G22.3, C10orf86, FLJ20003, NSE4A" ENSG00000107672 "NSE4 homolog A, SMC5-SMC6 complex component" Q9NXX6 10 121957091-121975217 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037459, HPA038412, HPA044872" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 2 Nucleoplasm "HPA037459: AB_10696932, HPA038412: AB_2676005, HPA044872: AB_2679124" "unprognostic (1.16e-3)" "unprognostic (2.86e-2)" "unprognostic (1.56e-1)" "unprognostic (3.73e-2)" "unprognostic (4.09e-3)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.72e-5)" "unprognostic (3.16e-2)" "unprognostic (7.47e-2)" "unprognostic (1.08e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (1.64e-1)" "unprognostic (8.13e-2)" "unprognostic (1.35e-1)" "unprognostic (7.01e-3)" BOD1L1 "BOD1L, FAM44A, FLJ33215, KIAA1327" ENSG00000038219 "Biorientation of chromosomes in cell division 1 like 1" Q8NFC6 4 13568738-13627725 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036943, HPA037362, HPA041290" Approved Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm "HPA036943: AB_2675397, HPA037362: AB_10670380, HPA041290: AB_2677393" "unprognostic (1.07e-1)" "unprognostic (3.27e-2)" "unprognostic (7.73e-2)" "unprognostic (2.29e-2)" "unprognostic (5.94e-2)" "unprognostic (6.15e-2)" "unprognostic (6.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-2)" "unprognostic (3.19e-1)" "unprognostic (9.02e-2)" "unprognostic (1.72e-1)" "prognostic favorable (3.48e-6)" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (6.60e-2)" ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1238.9;liver: 1978.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 1030.8;Proximal enterocytes: 610.9;Proximal tubular cells: 1113.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" C20orf203 FLJ33706 ENSG00000198547 "Chromosome 20 open reading frame 203" Q8NBC4 20 32631625-32673941 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Cone photoreceptor cells: 1.7;Excitatory neurons: 4.6;Horizontal cells: 3.1;Inhibitory neurons: 4.8;Oligodendrocyte precursor cells: 2.4;Oocytes: 3.7;Rod photoreceptor cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" NA NA "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 65: Neurons - Synaptic function" "unprognostic (6.24e-2)" "unprognostic (3.39e-3)" "unprognostic (8.39e-3)" "unprognostic (2.06e-1)" "unprognostic (1.19e-2)" "unprognostic (6.70e-3)" "unprognostic (7.53e-2)" "unprognostic (2.52e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (1.00e-2)" "unprognostic (1.39e-3)" "unprognostic (1.25e-10)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (7.46e-5)" CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 61.8;testis: 28.6" "Cell type enhanced" "Detected in many" "Early spermatids: 537.4;Late spermatids: 913.4;Oocytes: 225.7;Spermatocytes: 523.8;Spermatogonia: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 20.7" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Late spermatids - Unknown function" 2 "Nucleoplasm, Centriolar satellite" "HPA022048: AB_1853985" "unprognostic (1.47e-1)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.37e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (4.39e-3)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.67e-3)" "unprognostic (3.34e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.11e-9)" "unprognostic (2.19e-2)" "unprognostic (7.40e-3)" "unprognostic (4.46e-2)" "unprognostic (2.74e-1)" CHMP1A "CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A" ENSG00000131165 "Charged multivesicular body protein 1A" Q9HD42 16 89640816-89657738 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transcription, Transcription regulation, Transport" Repressor Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006776 Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 5: Enterocytes - Absorption" 14 "Nucleoplasm, Centrosome, Cytosol" "HPA006776: AB_1078520" "unprognostic (7.12e-2)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-2)" "unprognostic (7.29e-2)" "unprognostic (8.03e-3)" "unprognostic (1.28e-3)" "unprognostic (3.92e-3)" "unprognostic (2.42e-1)" "unprognostic (3.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.56e-1)" "unprognostic (7.98e-3)" "unprognostic (1.59e-2)" "unprognostic (4.19e-2)" "unprognostic (3.24e-1)" "unprognostic (1.73e-1)" CLASP1 "KIAA0622, MAST1" ENSG00000074054 "Cytoplasmic linker associated protein 1" Q7Z460 2 121337776-121649476 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 187.6;Excitatory neurons: 240.0;Inhibitory neurons: 203.5;Microglial cells: 125.2;Oligodendrocyte precursor cells: 218.9;Oligodendrocytes: 263.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065219 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Neurons - Neuronal signaling" 3 "HPA065219: AB_2685436" "unprognostic (6.21e-2)" "unprognostic (6.26e-2)" "unprognostic (2.45e-1)" "unprognostic (2.06e-3)" "unprognostic (4.06e-2)" "unprognostic (3.94e-1)" "unprognostic (7.87e-2)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (6.50e-4)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (5.41e-2)" "unprognostic (1.14e-1)" CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 167.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 52: Non-specific - Cell proliferation" 8 Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" FMC1-LUC7L2 C7orf55-LUC7L2 ENSG00000269955 "FMC1-LUC7L2 readthrough" 7 139341360-139422599 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045663, HPA051631" Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA045663: AB_2679410, HPA051631: AB_2681558" "unprognostic (2.54e-1)" "unprognostic (5.27e-2)" "unprognostic (3.21e-2)" "unprognostic (1.33e-3)" "unprognostic (1.38e-1)" "unprognostic (2.46e-3)" "unprognostic (1.68e-2)" "unprognostic (4.48e-2)" "unprognostic (2.26e-1)" "unprognostic (1.76e-3)" "unprognostic (1.10e-1)" "unprognostic (3.12e-2)" "unprognostic (6.42e-3)" HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" Immunity NA NA 2800000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 20 Nucleoplasm "CAB005873: AB_444360, HPA003506: AB_1079070, HPA073663: " "unprognostic (9.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-2)" "unprognostic (3.16e-2)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" "unprognostic (1.73e-1)" "unprognostic (2.64e-2)" "unprognostic (2.30e-2)" "unprognostic (4.28e-3)" "unprognostic (5.22e-3)" "unprognostic (4.67e-1)" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 53.1;Muller glia cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 67.0" "Group enriched" "Detected in all" 8 "granulocytes: 67.0;monocytes: 21.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "CAB045980, HPA053890, HPA055380, CAB080338" Supported Enhanced Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Cytosol "CAB045980: AB_11125836, CAB080338: , HPA053890: , HPA055380: AB_2682800" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (7.96e-3)" "unprognostic (1.35e-3)" "unprognostic (2.02e-2)" "unprognostic (6.45e-2)" "unprognostic (3.66e-1)" "unprognostic (3.34e-1)" "unprognostic (8.65e-3)" "unprognostic (1.82e-2)" "unprognostic (7.68e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-2)" "unprognostic (5.95e-2)" "unprognostic (9.75e-3)" "unprognostic (6.40e-3)" IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "pancreas: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 7 "cerebral cortex: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 4.9" "Group enriched" "Detected in some" 9 "granulocytes: 6.7;Spermatocytes: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cancer enriched" "Detected in single" 4 "lymphoma: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB010304 Approved "Secreted to blood" Interleukin NA NA 4130 "Cluster 46: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Spermatocytes - Spermatogenesis" 2 "CAB010304: AB_2296159" "unprognostic (1.66e-1)" "unprognostic (4.76e-2)" "unprognostic (5.30e-3)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (7.98e-2)" "unprognostic (2.03e-2)" "unprognostic (3.51e-2)" "unprognostic (1.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31114489-31131393 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 79: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 6: Ovarian stromal cells - Transcription" 3 Nucleoplasm "HPA066324: AB_2685658" "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favorable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 57: Platelets - Hemostasis" 22 Nucleoplasm "Golgi apparatus" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favorable (2.12e-4)" "unprognostic (6.03e-2)" MSH2 "COCA1, HNPCC, HNPCC1, MSH-2" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 83.3" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867, CAB080131" Supported Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 52: Non-specific - Cell proliferation" 8 Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , CAB080131: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" NBPF3 AE2 ENSG00000142794 "NBPF member 3" Q9H094 1 21440128-21485005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4" "Cell type enhanced" "Detected in many" "Early spermatids: 44.3;Excitatory neurons: 17.0;Inhibitory neurons: 17.7;Oligodendrocyte precursor cells: 27.4;Oligodendrocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "HPA042595, HPA043692, HPA044023, HPA046971, HPA058050" Approved NA NA "Cluster 27: T-cells - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Early spermatids - Unknown function" "HPA042595: , HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.49e-2)" "unprognostic (1.19e-2)" "unprognostic (5.09e-3)" "unprognostic (2.57e-2)" "unprognostic (3.11e-1)" "unprognostic (2.01e-1)" "unprognostic (2.82e-2)" "unprognostic (2.10e-1)" "unprognostic (2.22e-3)" "unprognostic (1.09e-1)" "unprognostic (3.11e-3)" "unprognostic (1.63e-1)" "unprognostic (5.31e-5)" "unprognostic (8.35e-2)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.66e-2)" NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 87.3;lymphoid tissue: 99.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.7;Extravillous trophoblasts: 16.7;Spermatocytes: 12.2;Undifferentiated cells: 16.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "basophil: 10.5;T-reg: 7.7" "Group enriched" "Detected in many" 14 "granulocytes: 10.5;T-cells: 7.7" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 58: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cell proliferation" 1 "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112905856-112933219 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 88.5;urinary bladder: 106.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.4;Hofbauer cells: 108.6;monocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 575.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 58: Macrophages - Innate immune response" 4 "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favorable (6.12e-6)" PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" PPP1R10 "CAT53, FB19, p99, PNUTS" ENSG00000204569 "Protein phosphatase 1 regulatory subunit 10" Q96QC0 6 30600413-30618612 "Predicted intracellular proteins" "DNA-binding, Protein phosphatase inhibitor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 7.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025501, HPA047248, HPA056756" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 2 Nucleoplasm "Nuclear bodies" "CAB025501: , HPA047248: AB_2679996, HPA056756: AB_2683227" "unprognostic (1.68e-1)" "prognostic favorable (4.84e-4)" "unprognostic (1.21e-1)" "unprognostic (9.31e-3)" "unprognostic (6.31e-2)" "unprognostic (9.57e-3)" "unprognostic (2.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "prognostic favorable (9.74e-5)" "unprognostic (2.72e-1)" "unprognostic (8.02e-3)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (2.89e-1)" "unprognostic (3.74e-2)" RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353979-37394734 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Non-specific - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 12: Squamous epithelial cells - Keratinization" 41 Nucleoplasm Cytosol "HPA050731: AB_2681222, HPA064925: AB_2685385" "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" RRBP1 "ES/130, hES, p180" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 482.3" "Cell type enhanced" "Detected in all" "dendritic cells: 719.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 38.6;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 320000 "Cluster 29: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "HPA009026: AB_1079852, HPA011924: AB_1856476" "unprognostic (1.56e-3)" "unprognostic (2.26e-3)" "unprognostic (8.46e-2)" "prognostic favorable (1.41e-4)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (6.63e-2)" "unprognostic (9.21e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.38e-4)" SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457893-43466046 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" NA NA 50000 "Cluster 33: Non-specific - ATP binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 15: Non-specific - Mixed function" 3 "Nuclear speckles" "CAB034889: AB_785899, HPA029005: AB_10610424" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.25e-2)" "unprognostic (6.41e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "unprognostic (1.27e-3)" "unprognostic (6.03e-3)" "prognostic unfavorable (2.82e-4)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (4.31e-1)" "unprognostic (1.18e-2)" STN1 "bA541N10.2, FLJ22559, OBFC1" ENSG00000107960 "STN1 subunit of CST complex" Q9H668 10 103856806-103918332 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037924, HPA037925" Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 11: Late spermatids - Unknown function" 16 Nucleoplasm "HPA037924: AB_10671636, HPA037925: AB_10672469" "unprognostic (1.50e-1)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (5.58e-3)" "unprognostic (6.01e-2)" "unprognostic (1.53e-2)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (5.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "unprognostic (3.76e-1)" "prognostic favorable (1.12e-6)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.83e-2)" TAPBPL "FLJ10143, TAPBP-R, TAPBPR" ENSG00000139192 "TAP binding protein like" Q9BX59 12 6451690-6466517 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 84.1;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039545 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 77: Plasma cells - Protein processing" 8 "HPA039545: AB_10673360" "prognostic favorable (1.98e-4)" "unprognostic (3.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (4.61e-2)" "unprognostic (1.91e-1)" "unprognostic (7.64e-2)" "unprognostic (4.07e-2)" "unprognostic (3.18e-1)" "unprognostic (5.66e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.04e-5)" "unprognostic (3.53e-2)" "unprognostic (7.61e-2)" "unprognostic (6.28e-2)" "prognostic favorable (7.86e-4)" TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 157 Nucleoplasm "Vesicles, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" Hydrolase "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2404.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 930.9;Ductal cells: 1004.7;Schwann cells: 1165.7" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1667.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Neuroblastoma: 1234.9" "Adipose subcutaneous - Adipose progenitor cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 15: Non-specific - Mixed function" 7 Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 52: Non-specific - Cell proliferation" 4 Nucleoplasm "HPA062422: AB_2684757, HPA068953: AB_2686062" "unprognostic (2.52e-2)" "unprognostic (1.81e-3)" "unprognostic (6.75e-2)" "unprognostic (4.01e-2)" "unprognostic (4.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-4)" "unprognostic (2.93e-2)" "unprognostic (4.67e-2)" "unprognostic (1.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.53e-2)" "unprognostic (3.52e-7)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (8.84e-2)" "unprognostic (3.72e-2)" YTHDF2 "CAHL, HGRG8, NY-REN-2" ENSG00000198492 "YTH N6-methyladenosine RNA binding protein 2" Q9Y5A9 1 28736621-28769775 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Immunity, Innate immunity, Mitosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030063, HPA054080, HPA059621" Approved Enhanced "Cytosol,Cytoplasmic bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 56: Non-specific - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Cytoplasmic bodies" "HPA030063: AB_2732453, HPA054080: AB_2682371, HPA059621: AB_2684084" "unprognostic (8.75e-2)" "unprognostic (1.90e-2)" "unprognostic (4.66e-3)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.14e-9)" "unprognostic (1.75e-2)" "unprognostic (4.82e-2)" "unprognostic (4.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.11e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-1)" "unprognostic (6.38e-2)" "unprognostic (9.29e-2)" "unprognostic (6.97e-3)" ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 42.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.6;Erythroid cells: 123.9;Extravillous trophoblasts: 110.5;Late spermatids: 208.2;Oocytes: 86.8;Spermatocytes: 125.4;Spermatogonia: 87.2;Undifferentiated cells: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cell proliferation" 21 "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Adrenocortical cancer: 1042.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 38000 "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 3 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: AB_1847954, HPA028277: AB_10603664" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.03e-2)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (7.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.24e-3)" "unprognostic (7.11e-2)" "unprognostic (1.64e-3)" "unprognostic (4.10e-3)" "unprognostic (3.04e-3)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-2)" XNDC1N ENSG00000254469 "XRCC1 N-terminal domain containing 1, N-terminal like" Q6ZNB5 11 71865504-71928654 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 33.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA051121, HPA051124" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" Nucleoli "Mitotic chromosome" "HPA051121: AB_2681349, HPA051124: " "unprognostic (1.66e-1)" "unprognostic (1.19e-2)" "unprognostic (2.23e-1)" "unprognostic (1.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (9.79e-4)" "unprognostic (5.91e-3)" "unprognostic (5.04e-3)" "unprognostic (7.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (3.60e-1)" "unprognostic (3.12e-3)" ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "intestine: 176.3;kidney: 434.0;liver: 266.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Gastric mucus-secreting cells: 31.2;Proximal enterocytes: 137.7;Proximal tubular cells: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003695, HPA036174, HPA036175, HPA071834" Enhanced Approved Vesicles NA NA 23000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 7 Vesicles "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989, HPA071834: " "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.8" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 149.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 21: Testis - Unknown function" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: AB_10672615, HPA057566: AB_2683470" "unprognostic (1.37e-1)" "unprognostic (4.28e-2)" "unprognostic (5.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.72e-2)" "unprognostic (4.81e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" C8orf48 FLJ25402 ENSG00000164743 "Chromosome 8 open reading frame 48" Q96LL4 8 13566869-13568288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.8" "Group enriched" "Detected in many" 6 "Early spermatids: 38.1;Late spermatids: 52.2;Spermatocytes: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026107, HPA027440" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Late spermatids - Spermatogenesis" 17 Cytosol Nucleoplasm "HPA026107: AB_10600765, HPA027440: AB_10601678" "unprognostic (1.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.07e-2)" "unprognostic (9.01e-2)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (4.84e-3)" "unprognostic (7.70e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-1)" "unprognostic (1.41e-3)" "unprognostic (7.74e-4)" "unprognostic (1.78e-1)" "unprognostic (8.42e-3)" "unprognostic (8.70e-2)" SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 453.4;skeletal muscle: 290.4;tongue: 209.7" "Cell type enhanced" "Detected in all" "Early spermatids: 139.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" 6 "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 267.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 932.6;Ductal cells: 622.5;Extravillous trophoblasts: 701.2;Syncytiotrophoblasts: 692.3;Undifferentiated cells: 538.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1212.9;lung: 1626.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1247.2;Cardiomyocytes: 393.1;Endothelial cells: 861.7;Hepatocytes: 654.0;Microglial cells: 339.1;Smooth muscle cells: 471.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 48.1;liver cancer: 106.6;skin cancer: 72.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 1630000000000 170000000000 "Cluster 1: T-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 51 "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 45.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Breast glandular cells: 6.1;Early spermatids: 3.7;Hepatocytes: 3.7;Prostatic glandular cells: 5.2;Spermatocytes: 3.1" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "breast cancer: 11.0;prostate cancer: 4.7" "Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 73: Breast - Lactation" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 167.3;Lymphatic endothelial cells: 152.7;monocytes: 47.5;Smooth muscle cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 106.8" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 3 "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Fibroblasts - ECM organization" 5 "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" COX6A1 "COX6A, COX6AL" ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1660.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2004.4;Proximal enterocytes: 1967.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062394 Approved Supported Mitochondria NA NA 85000 "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 Mitochondria "HPA062394: AB_2684749" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (5.10e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-1)" "unprognostic (8.78e-2)" "unprognostic (3.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (3.22e-2)" "unprognostic (2.82e-1)" "prognostic favorable (6.50e-7)" "unprognostic (2.53e-1)" "unprognostic (1.31e-1)" "unprognostic (5.48e-2)" "unprognostic (2.63e-2)" CRLF3 "CREME9, CYTOR4" ENSG00000176390 "Cytokine receptor like factor 3" Q8IUI8 17 30769388-30824692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 34.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007596 Enhanced Approved "Plasma membrane,Cytosol" NA NA 210000 "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 55: Non-specific - Transcription" 24 "Plasma membrane, Cytosol" "HPA007596: AB_1847241" "unprognostic (1.02e-1)" "unprognostic (9.79e-2)" "unprognostic (7.12e-2)" "unprognostic (9.65e-2)" "unprognostic (2.28e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-2)" "unprognostic (9.22e-2)" "unprognostic (1.00e-2)" "unprognostic (3.10e-2)" "unprognostic (5.81e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.31e-7)" "unprognostic (3.35e-1)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (6.51e-2)" CTCFL "BORIS, CT27, dJ579F20.2" ENSG00000124092 "CCCTC-binding factor like" Q8NI51 20 57495966-57525652 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 10.8" "Group enriched" "Detected in some" 10 "Spermatocytes: 73.6;Spermatogonia: 125.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 19.0;cervical cancer: 18.4" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA001472 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA001472: AB_1078583" "unprognostic (2.50e-1)" "unprognostic (4.01e-2)" "unprognostic (7.70e-2)" "unprognostic (1.85e-5)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-2)" "unprognostic (5.26e-3)" "unprognostic (3.60e-1)" "unprognostic (2.20e-1)" "unprognostic (9.00e-2)" "unprognostic (4.16e-2)" "unprognostic (4.75e-4)" "unprognostic (2.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.84e-2)" CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 570.5" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 262.5" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 11.2;liver cancer: 18.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3492.7" "Group enriched" "Detected in some" 59 "Hepatocytes: 2573.4;Proximal enterocytes: 1348.0" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 2 Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 56.8;vagina: 22.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 53.8;Breast glandular cells: 8.5;monocytes: 8.9;Prostatic glandular cells: 11.1;Suprabasal keratinocytes: 31.2" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 8 "monocytes: 14.2;T-cells: 4.3" "Cancer enriched" "Detected in some" 31 "Bone cancer: 42.8" "Lung - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 4 "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" DCTN2 "DCTN-50, RBP50" ENSG00000175203 "Dynactin subunit 2" Q13561 12 57529633-57547224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039715, HPA040040" Enhanced Supported Centrosome,Cytosol NA NA 630000 "Cluster 29: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 35 Centrosome Cytosol "HPA039715: AB_10795154, HPA040040: AB_10794870" "unprognostic (1.70e-2)" "unprognostic (1.82e-1)" "unprognostic (1.54e-1)" "unprognostic (6.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" "unprognostic (1.71e-1)" "unprognostic (4.26e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (9.50e-3)" "unprognostic (2.09e-1)" "unprognostic (1.52e-3)" "unprognostic (3.41e-3)" DDB1 ENSG00000167986 "Damage specific DNA binding protein 1" Q16531 11 61299451-61342596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 358.5;Cytotrophoblasts: 275.0;Rod photoreceptor cells: 458.3;Syncytiotrophoblasts: 400.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032821, HPA045174, HPA068456" Approved Enhanced Nucleoplasm NA NA 440000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 17 Nucleoplasm "CAB032821: AB_639050, HPA045174: AB_2679242, HPA068456: AB_2685992" "unprognostic (3.45e-1)" "unprognostic (8.38e-2)" "prognostic favorable (7.09e-4)" "unprognostic (1.21e-1)" "unprognostic (6.56e-2)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" "unprognostic (9.74e-3)" "unprognostic (1.09e-1)" "unprognostic (7.42e-3)" "unprognostic (3.11e-1)" "prognostic favorable (1.51e-8)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (7.30e-2)" "unprognostic (1.25e-3)" DMXL2 "DFNA71, KIAA0856, RC3" ENSG00000104093 "Dmx like 2" Q8TDJ6 15 51447711-51622833 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Diabetes mellitus, Disease variant, Epilepsy, Hypogonadotropic hypogonadism, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.2;Inhibitory neurons: 117.8;Kupffer cells: 84.3;Macrophages: 102.6;monocytes: 175.0;Oligodendrocyte precursor cells: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.8;intermediate monocyte: 2.2;neutrophil: 2.2;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 4 "granulocytes: 2.2;monocytes: 2.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039375 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Neuronal - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA039375: AB_10673610" "unprognostic (5.66e-2)" "unprognostic (9.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-2)" "unprognostic (8.38e-2)" "unprognostic (3.39e-1)" "unprognostic (2.32e-1)" "unprognostic (3.67e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (1.09e-1)" "unprognostic (1.67e-1)" "unprognostic (8.60e-3)" "unprognostic (2.70e-2)" DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 20.9;Proximal tubular cells: 31.0" "Cancer enriched" "Detected in some" 90 "testis cancer: 46.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 5.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 "Nuclear speckles" "HPA055234: AB_2682750, HPA066780: AB_2685719" "unprognostic (1.05e-4)" "unprognostic (1.91e-1)" "unprognostic (2.73e-9)" "unprognostic (2.77e-1)" "unprognostic (5.28e-2)" DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.8;Extravillous trophoblasts: 18.1;Oocytes: 50.7;Spermatogonia: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 2 Nucleoplasm "HPA023780: AB_2671311, HPA024401: AB_2671557" "unprognostic (7.36e-3)" "unprognostic (8.24e-2)" "unprognostic (1.56e-1)" "unprognostic (4.71e-3)" "unprognostic (9.91e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.92e-6)" "prognostic unfavorable (3.93e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (3.24e-3)" "unprognostic (8.12e-3)" "unprognostic (2.72e-2)" "unprognostic (2.32e-9)" "unprognostic (2.75e-2)" "unprognostic (5.01e-1)" "unprognostic (4.40e-2)" "unprognostic (8.18e-2)" FLI1 "EWSR2, FLI-1, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.2" "Cell type enhanced" "Detected in many" "B-cells: 61.8;Endothelial cells: 79.8;Kupffer cells: 88.8;Microglial cells: 221.0;monocytes: 70.9;NK-cells: 74.1;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 39.0;Myeloma: 29.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" GBA1 "GBA, GLUC" ENSG00000177628 "Glucosylceramidase beta 1" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 15.3;Schwann cells: 13.4;Syncytiotrophoblasts: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" Enzyme NA NA 470000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 312.6;Extravillous trophoblasts: 473.6;Hofbauer cells: 307.5;Kupffer cells: 228.0;Langerhans cells: 487.0;Macrophages: 267.3;monocytes: 215.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" "No annotated function" NA NA 64000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" GLIPR1L2 MGC39497 ENSG00000180481 "GLIPR1 like 2" Q4G1C9 12 75391089-75432688 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 45.3" "Group enriched" "Detected in many" 12 "Early spermatids: 367.6;Spermatocytes: 266.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039795, HPA039866" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 31: Spermatocytes - Spermatogenesis" "Golgi apparatus" Vesicles "HPA039795: AB_10805595, HPA039866: AB_10795235" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.27e-1)" "unprognostic (7.74e-2)" "unprognostic (1.33e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "unprognostic (7.68e-3)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (5.91e-2)" "unprognostic (2.57e-2)" HAUS6 "dgt6, FAM29A, FLJ20060, KIAA1574" ENSG00000147874 "HAUS augmin like complex subunit 6" Q7Z4H7 9 19053141-19102904 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 132.1;Spermatocytes: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020960, HPA020965" Approved Approved "Nuclear speckles,Centriolar satellite,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 21: Early spermatids - Spermatogenesis" 8 "Centriolar satellite, Cytosol" "Nuclear speckles" "HPA020960: AB_1848393, HPA020965: AB_1848394" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (6.04e-3)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.21e-1)" "unprognostic (2.15e-1)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.13e-5)" "unprognostic (2.52e-1)" "unprognostic (1.68e-1)" "unprognostic (3.13e-2)" "unprognostic (2.03e-1)" HOXC10 HOX3I ENSG00000180818 "Homeobox C10" Q9NYD6 12 53985065-53990279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 109.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 17.5;Distal tubular cells: 27.7;Proximal tubular cells: 84.8" "Cancer enhanced" "Detected in many" "renal cancer: 20.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in single" 418 "spinal cord: 41.7" HPA053919 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "Nuclear bodies" Nucleoplasm "HPA053919: AB_2682308" "unprognostic (1.44e-2)" "unprognostic (1.09e-1)" "unprognostic (4.56e-4)" "unprognostic (1.57e-1)" "unprognostic (1.59e-3)" "unprognostic (1.98e-1)" "unprognostic (1.73e-2)" "unprognostic (1.23e-1)" "unprognostic (9.60e-3)" "unprognostic (3.96e-2)" "unprognostic (7.37e-3)" "unprognostic (2.25e-2)" "unprognostic (3.56e-2)" "unprognostic (5.07e-2)" "unprognostic (5.24e-3)" "unprognostic (1.91e-1)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.1;Langerhans cells: 1.4;Proximal enterocytes: 3.4;Spermatocytes: 3.4;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.8;breast cancer: 14.9" "Breast - Breast glandular cells (progenitors), Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "spinal cord: 1.4" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 65: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Breast myoepithelial cells: 4.2;Melanocytes: 1.7;Oocytes: 1.5;Spermatogonia: 1.6;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA051634 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 10.6;Ciliated cells: 17.4;Secretory cells: 6.0;Squamous epithelial cells: 7.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "pons: 34.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_2" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 64 "medulla oblongata: 6.4;pons: 4.8;spinal cord: 7.8" HPA053910 Supported Nucleoplasm NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 22 Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" HOXC5 "HOX3, HOX3D" ENSG00000172789 "Homeobox C5" Q00444 12 54033050-54035361 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.0" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 2.9;Gastric mucus-secreting cells: 1.2;Squamous epithelial cells: 1.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Group enriched" "Detected in some" 14 "medulla oblongata: 5.9;pons: 7.6;spinal cord: 4.2;white matter: 2.5" "Immune cell enhanced" "Detected in single" "gdT-cell: 3.0" "Lineage enriched" "Detected in single" 31 "T-cells: 3.0" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_2" "Region enriched" "Detected in single" 46 "pons and medulla: 4.6" "Group enriched" "Detected in some" 5 "medulla oblongata: 2.0;spinal cord: 2.8" HPA026794 Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 9 Nucleoplasm "Cell Junctions" "HPA026794: AB_10612118" "unprognostic (1.57e-1)" "unprognostic (7.73e-3)" "unprognostic (1.70e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-3)" "unprognostic (2.87e-3)" "unprognostic (6.89e-2)" "unprognostic (9.53e-3)" "unprognostic (1.86e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-3)" "unprognostic (1.17e-2)" "unprognostic (7.53e-3)" "unprognostic (2.19e-3)" "unprognostic (1.08e-2)" HOXC6 "HOX3, HOX3C" ENSG00000197757 "Homeobox C6" P09630 12 53990624-54030823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.2;ovary: 25.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 12.3;Fibroblasts: 12.3;Leydig cells: 20.6;Melanocytes: 15.5;Ovarian stromal cells: 27.1;Peritubular cells: 14.3;Smooth muscle cells: 13.1;Spermatocytes: 39.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 11 "medulla oblongata: 6.9;pons: 9.4;spinal cord: 6.7;white matter: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 41.4" "Lung - Fibroblast_2" "Region enriched" "Detected in single" 15 "pons and medulla: 1.4" "Region enriched" "Detected in some" 15 "spinal cord: 14.9" HPA054981 Supported Nucleoplasm,Cytosol No No "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" Nucleoplasm Cytosol "HPA054981: AB_2682662" "unprognostic (3.54e-2)" "unprognostic (9.20e-2)" "unprognostic (1.68e-6)" "unprognostic (3.92e-2)" "unprognostic (1.10e-3)" "unprognostic (5.01e-4)" "unprognostic (5.52e-3)" "unprognostic (3.32e-3)" "unprognostic (2.81e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (3.55e-6)" "unprognostic (8.63e-2)" "unprognostic (5.76e-2)" "unprognostic (1.40e-2)" "unprognostic (4.71e-2)" HOXC8 "HOX3, HOX3A" ENSG00000037965 "Homeobox C8" P31273 12 54008985-54012769 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 15.1;skeletal muscle: 16.2" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.4;Leydig cells: 8.1;Melanocytes: 10.3;Ovarian stromal cells: 9.0;Peritubular cells: 11.5;Proximal tubular cells: 7.2;Sertoli cells: 10.9;Smooth muscle cells: 12.4;Spermatocytes: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 25.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 144 "spinal cord: 14.3" "HPA028911, CAB037020" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 35: Non-specific - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 74 "Nucleoplasm, Microtubules" "CAB037020: AB_1840935, HPA028911: AB_10602236" "unprognostic (1.03e-1)" "unprognostic (5.90e-2)" "unprognostic (6.26e-6)" "unprognostic (4.89e-2)" "unprognostic (5.20e-4)" "unprognostic (5.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (1.45e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.47e-5)" "unprognostic (2.47e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-2)" "unprognostic (1.14e-2)" HOXC9 "HOX3, HOX3B" ENSG00000180806 "Homeobox C9" P31274 12 53994895-54003337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.7;skeletal muscle: 25.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 40.0;Melanocytes: 42.9;Oocytes: 52.2;Proximal tubular cells: 24.0;Smooth muscle cells: 17.4;Spermatogonia: 24.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 26.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 10.1" "HPA063965, HPA072160" Enhanced Nucleoplasm NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 14 Nucleoplasm "HPA063965: AB_2685162, HPA072160: AB_2686491" "unprognostic (2.38e-1)" "unprognostic (1.03e-1)" "unprognostic (3.19e-5)" "unprognostic (1.23e-1)" "unprognostic (4.09e-3)" "unprognostic (7.12e-2)" "unprognostic (6.92e-3)" "unprognostic (1.06e-3)" "unprognostic (4.32e-1)" "unprognostic (1.58e-2)" "unprognostic (7.38e-2)" "unprognostic (4.08e-2)" "unprognostic (9.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.01e-1)" "unprognostic (2.74e-2)" "unprognostic (1.53e-1)" HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 40.8" "Cell type enhanced" "Detected in some" "Adipocytes: 9.4;Basal prostatic cells: 16.9;Collecting duct cells: 27.2;Distal tubular cells: 18.4;Early spermatids: 8.6;Late spermatids: 11.1;Leydig cells: 9.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in many" 10 "medulla oblongata: 18.6;pons: 12.0;spinal cord: 11.8;white matter: 9.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.3" "Prostate - Endothelial cells, Skin - Endothelial cells" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.4;pons: 1.5;spinal cord: 4.1" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 3 Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: AB_2685083" "unprognostic (1.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.57e-4)" "unprognostic (1.47e-3)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (7.44e-2)" HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 23.6;epididymis: 27.3" "Cell type enhanced" "Detected in some" "Adipocytes: 8.3;Basal prostatic cells: 13.0;Collecting duct cells: 25.3;Leydig cells: 6.8;Proximal tubular cells: 6.6;Secretory cells: 7.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in some" 24 "medulla oblongata: 22.8;pons: 11.2;spinal cord: 17.4;white matter: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.3" "Prostate - Endothelial cells, Skin - Endothelial cells" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 7.2;spinal cord: 9.6" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 2 Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" HOXD9 "HOX4, HOX4C" ENSG00000128709 "Homeobox D9" P28356 2 176122719-176124937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 40.9;endometrium 1: 55.9;kidney: 50.7" "Cell type enhanced" "Detected in many" "Adipocytes: 37.2;Basal prostatic cells: 23.9;Collecting duct cells: 23.3;Distal tubular cells: 46.1;Endothelial cells: 36.5;Leydig cells: 34.4;Lymphatic endothelial cells: 52.6;Oocytes: 25.0;Peritubular cells: 26.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.1;spinal cord: 1.2;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 23.4;Neuroblastoma: 22.6" "Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 105 "spinal cord: 10.5" HPA068683 Supported Nucleoplasm,Nucleoli NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Nucleoplasm, Nucleoli" "HPA068683: AB_2686018" "unprognostic (1.89e-1)" "unprognostic (9.41e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.03e-2)" "prognostic favorable (9.58e-4)" "prognostic unfavorable (1.08e-5)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-3)" "unprognostic (6.71e-2)" "unprognostic (4.77e-3)" "unprognostic (8.38e-2)" "unprognostic (5.94e-2)" "unprognostic (1.89e-1)" "unprognostic (9.44e-2)" IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "T-cells: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 862 "basophil: 476.8" "Lineage enriched" "Detected in single" 862 "granulocytes: 476.8" "Cancer enhanced" "Detected in single" "lymphoma: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA072995, CAB078477" Approved "Secreted to blood" Interleukin NA NA 13600 "Cluster 46: Basophils - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 50: Lymphoma - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "CAB078477: AB_417057, HPA072995: AB_2732215" "unprognostic (3.40e-2)" "unprognostic (9.19e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-1)" "unprognostic (7.33e-2)" "unprognostic (2.26e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-10)" "unprognostic (9.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.24e-2)" JADE1 "JADE-1, PHF17" ENSG00000077684 "Jade family PHD finger 1" Q6IE81 4 128809700-128875224 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020016, HPA072897" Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Smooth muscle cells - Signal transduction" 4 Nucleoplasm Centrosome "HPA020016: AB_1855292, HPA072897: " "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.63e-2)" "unprognostic (3.19e-1)" "unprognostic (2.09e-2)" "unprognostic (7.59e-2)" "unprognostic (6.96e-3)" "unprognostic (6.93e-2)" "unprognostic (8.16e-2)" "unprognostic (9.39e-2)" "unprognostic (8.38e-3)" "prognostic favorable (8.22e-6)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (9.92e-2)" "unprognostic (1.68e-1)" KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043879-5046788 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 59.0;heart muscle: 38.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 128.0;Cardiomyocytes: 21.5;dendritic cells: 18.9;Horizontal cells: 34.0;Smooth muscle cells: 29.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Region enriched" "Detected in all" 7 "choroid plexus: 113.8" "Immune cell enriched" "Detected in single" 122 "plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 122 "dendritic cells: 12.2" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021516, CAB022562" Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" 2 "CAB022562: , HPA021516: AB_2670732" "unprognostic (3.87e-1)" "unprognostic (9.91e-3)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (7.06e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (5.08e-3)" "unprognostic (6.73e-4)" "unprognostic (1.92e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (3.08e-2)" KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790727-29805385 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.1" "Group enriched" "Detected in all" 4 "Cardiomyocytes: 648.1;Hepatocytes: 580.3;Proximal tubular cells: 209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 43: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 2.9;salivary gland: 9.7" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 850.7" "Group enriched" "Detected in some" 5 "cervical cancer: 0.7;head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 2.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" NA NA 280000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 50: Lymphoma - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 33 "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (2.75e-1)" "unprognostic (9.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.73e-2)" KRT33A "Ha-3I, Krt1-3, KRTHA3A" ENSG00000006059 "Keratin 33A" O76009 17 41346092-41350828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 46.0" "Group enriched" "Detected in some" 5 "Basal squamous epithelial cells: 1.8;Late spermatids: 1.3;Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA055194 Supported NA NA 160000000 "Cluster 13: Skin - Cornification" "Cluster 11: Neuronal - Sensory perception" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA055194: AB_2682733" "unprognostic (1.93e-1)" "unprognostic (1.30e-2)" "unprognostic (4.58e-2)" "unprognostic (4.34e-1)" "unprognostic (2.16e-1)" KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 80.2" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 3.1;Oocytes: 10.3;Suprabasal keratinocytes: 5.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Testis - Late spermatids" HPA055194 Supported NA NA 350000000 "Cluster 13: Skin - Cornification" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Suprabasal keratinocytes - Cornification" 65 "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2454.5;esophagus: 7132.4;vagina: 4797.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5591.4;Serous glandular cells: 2833.1;Suprabasal keratinocytes: 12137.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 2730.0;head and neck cancer: 1413.8" "Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 30 "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" KRT8 "CARD2, CK-8, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1323.0;stomach 1: 793.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 12319.1;Ductal cells: 5203.4;Extravillous trophoblasts: 6075.3;Paneth cells: 8520.4;Proximal enterocytes: 7547.1;Syncytiotrophoblasts: 5966.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 64.6" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 20 "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 3 Nucleoplasm Cytosol "HPA030342: AB_10610138" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.66e-1)" "unprognostic (2.59e-1)" "unprognostic (1.42e-2)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.39e-2)" "prognostic favorable (6.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" MSH6 "GTBP, MSH-6" ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 92.7" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 52: Non-specific - Cell proliferation" 3 Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 22.6;Basal prostatic cells: 29.9;Collecting duct cells: 27.2;Exocrine glandular cells: 66.0;Fibroblasts: 47.9;Salivary duct cells: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 42.4" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" "No annotated function" NA NA 2600000 "Cluster 13: Skin - Cornification" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" NBPF1 "FLJ20719, KIAA1693" ENSG00000219481 "NBPF member 1" Q3BBV0 1 16562319-16613562 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 70.0;Inhibitory neurons: 49.9;Oligodendrocyte precursor cells: 64.1;Oligodendrocytes: 81.9;Spermatocytes: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 1 Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (8.16e-3)" "unprognostic (6.96e-2)" "unprognostic (1.33e-2)" "unprognostic (6.09e-2)" "unprognostic (3.49e-1)" "unprognostic (4.76e-2)" "unprognostic (1.15e-5)" "unprognostic (2.16e-2)" "unprognostic (5.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.90e-2)" "unprognostic (2.14e-2)" "prognostic favorable (1.06e-4)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.68e-1)" NBPF10 AG1 ENSG00000271425 "NBPF member 10" Q6P3W6 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 19.4;Paneth cells: 29.1;Squamous epithelial cells: 25.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" NBPF14 DJ328E19.C1.1 ENSG00000270629 "NBPF member 14" 1 148531385-148679742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Paneth cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Skin - Cornification" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.28e-2)" "unprognostic (3.88e-2)" "unprognostic (7.92e-3)" "unprognostic (7.13e-2)" "unprognostic (2.46e-1)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (7.69e-4)" "unprognostic (7.23e-3)" "unprognostic (5.20e-2)" "unprognostic (5.15e-4)" "unprognostic (2.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-1)" "unprognostic (2.52e-2)" NBPF15 "MGC8902, NBPF16" ENSG00000266338 "NBPF member 15" Q8N660 1 144421390-144461676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 14.5;Basal squamous epithelial cells: 14.6;Excitatory neurons: 16.3;Squamous epithelial cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.6;NK-cells: 2.3;T-cells: 3.9" "Low cancer specificity" "Detected in all" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" Cytosol "HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (2.03e-1)" "unprognostic (7.10e-2)" "unprognostic (1.96e-1)" "unprognostic (4.82e-3)" "unprognostic (1.84e-3)" "unprognostic (3.50e-3)" "unprognostic (8.16e-3)" "unprognostic (1.19e-1)" "unprognostic (4.73e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (4.11e-5)" "unprognostic (1.36e-1)" "unprognostic (1.91e-1)" "unprognostic (6.67e-2)" "unprognostic (6.26e-2)" NBPF20 ENSG00000162825 "NBPF member 20" 1 145289900-145425603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "dendritic cells: 14.2;Early spermatids: 31.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 18: Early spermatids - Unknown function" Cytosol "HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (6.25e-3)" "unprognostic (4.74e-2)" "unprognostic (1.23e-1)" "unprognostic (8.05e-2)" "unprognostic (1.20e-2)" "unprognostic (1.40e-1)" "unprognostic (2.25e-2)" "unprognostic (5.37e-2)" "unprognostic (3.22e-3)" "unprognostic (3.54e-1)" "unprognostic (4.26e-4)" "unprognostic (1.69e-1)" "unprognostic (1.45e-4)" "unprognostic (9.74e-2)" "unprognostic (5.21e-2)" "unprognostic (1.00e-1)" "unprognostic (1.70e-1)" NBPF4 FLJ32833 ENSG00000196427 "NBPF member 4" Q96M43 1 108222464-108244081 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 1.1;testis: 4.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.9" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.2" "Breast - Breast glandular cells, Testis - Early spermatids" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 13: Spermatids - Transcription" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (6.33e-2)" "unprognostic (2.08e-1)" "unprognostic (2.18e-2)" "unprognostic (8.29e-2)" "unprognostic (2.90e-1)" "unprognostic (8.73e-2)" NBPF6 ENSG00000186086 "NBPF member 6" Q5VWK0 1 108450282-108471920 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 2.7;testis: 2.6" "Cell type enhanced" "Detected in single" "Excitatory neurons: 1.2" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.5" "Region enhanced" "Detected in some" "basal ganglia: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Testis - Early spermatids" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (4.36e-2)" "unprognostic (5.87e-2)" "unprognostic (4.62e-2)" "unprognostic (2.39e-1)" "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" NBPF8 NBPF8P ENSG00000270231 "NBPF member 8" 1 120415035-120469676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 8.4;Macrophages: 8.1;Oligodendrocyte precursor cells: 12.3;Squamous epithelial cells: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Cytosol NA NA "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 49: Non-specific - Transcription" Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (1.63e-2)" "unprognostic (4.82e-2)" "unprognostic (7.19e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.44e-1)" "unprognostic (1.18e-1)" "unprognostic (9.64e-3)" "unprognostic (9.41e-3)" "unprognostic (8.32e-2)" "unprognostic (1.99e-1)" "unprognostic (3.97e-2)" "unprognostic (1.75e-9)" "unprognostic (2.35e-1)" "unprognostic (1.82e-1)" "unprognostic (5.01e-2)" "unprognostic (9.26e-2)" NBPF9 AE01 ENSG00000269713 "NBPF member 9" P0DPF3 1 149052186-149103561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (1.25e-2)" "unprognostic (1.02e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-1)" "unprognostic (3.33e-3)" "unprognostic (1.94e-1)" "unprognostic (2.15e-2)" "unprognostic (2.93e-1)" "unprognostic (2.10e-1)" "unprognostic (6.90e-2)" "unprognostic (9.42e-6)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (6.63e-3)" "unprognostic (8.80e-2)" NUFIP1 "NUFIP, Rsa1" ENSG00000083635 "Nuclear FMR1 interacting protein 1" Q9UHK0 13 44939249-44989471 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 69.3;Oocytes: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029958, HPA029959" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 18: Non-specific - Translation" "Cluster 40: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 2 Nucleoplasm Nucleoli "HPA029958: AB_10598911, HPA029959: AB_10602308" "unprognostic (2.01e-1)" "unprognostic (5.32e-3)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (1.70e-2)" "unprognostic (2.98e-3)" "unprognostic (2.32e-1)" "unprognostic (1.45e-2)" "unprognostic (2.91e-2)" "unprognostic (9.74e-3)" "unprognostic (4.52e-1)" "unprognostic (3.95e-2)" "unprognostic (3.73e-2)" "unprognostic (4.04e-2)" "unprognostic (4.89e-2)" "unprognostic (3.31e-1)" "unprognostic (5.24e-2)" PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330514-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.3;Horizontal cells: 1.3;Melanocytes: 1.7;Skeletal myocytes: 6.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.9;Horizontal cells: 15.1;Skeletal myocytes: 66.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Bipolar cells: 3.0;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.0;Fibroblasts: 2.3;Peritubular cells: 1.6;Schwann cells: 4.3;Skeletal myocytes: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.1;Fibroblasts: 2.2;Horizontal cells: 1.9;Ovarian stromal cells: 1.9;Schwann cells: 5.4;Skeletal myocytes: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364162-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.6;Endometrial stromal cells: 8.7;Skeletal myocytes: 31.2" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.5;Skeletal myocytes: 26.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Endometrial stromal cells: 2.1;Prostatic glandular cells: 2.4;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.8;Horizontal cells: 5.0;Ovarian stromal cells: 5.2;Skeletal myocytes: 21.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402778-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.7;Cardiomyocytes: 2.3;Horizontal cells: 2.5;Skeletal myocytes: 7.8" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350099-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.4" "Group enriched" "Detected in some" 6 "Early spermatids: 3.7;Late spermatids: 8.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 61: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141359994-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Cardiomyocytes: 2.0;Mucus glandular cells: 1.1" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Salivary duct cells: 1.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Lymphatic endothelial cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.7;testis cancer: 14.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397947-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.6;Mucus glandular cells: 1.8;Skeletal myocytes: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 8.2;Skeletal myocytes: 16.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 55: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Fibroblasts: 4.3;Lymphatic endothelial cells: 8.6;Schwann cells: 5.6;Skeletal myocytes: 8.8" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2;Rhabdoid: 16.1" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 351.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 6.2;Bipolar cells: 7.5;Fibroblasts: 12.6;Mesothelial cells: 10.8;Serous glandular cells: 9.0;Skeletal myocytes: 7.8" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 25 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 49: Non-specific - Transcription" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512975 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 19.4;retina: 6.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 3.1;testis cancer: 9.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 29.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;testis cancer: 6.8" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" POC1B-GALNT4 ENSG00000259075 "POC1B-GALNT4 readthrough" 12 89519408-89526262 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "B-cells: 2.3;Basal squamous epithelial cells: 1.6;Erythroid cells: 1.9;Gastric mucus-secreting cells: 1.2;Glandular and luminal cells: 1.1;Schwann cells: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA076116 Approved "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 49: Non-specific - Transcription" "Golgi apparatus" "HPA076116: AB_2686778" "unprognostic (4.91e-2)" "unprognostic (5.00e-2)" "unprognostic (1.26e-1)" "unprognostic (2.77e-6)" "unprognostic (7.99e-2)" "unprognostic (1.55e-2)" "unprognostic (2.26e-1)" "unprognostic (2.64e-1)" "unprognostic (7.67e-2)" "unprognostic (2.44e-1)" "unprognostic (7.72e-3)" "unprognostic (1.95e-1)" "unprognostic (1.61e-4)" "unprognostic (7.65e-3)" "unprognostic (1.05e-1)" "unprognostic (2.15e-2)" "unprognostic (5.16e-2)" POU5F1 "MGC22487, OCT-4, OCT3, Oct3/4, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.0" "Cell type enriched" "Detected in many" 4 "Glandular and luminal cells: 48.5" "Cancer enriched" "Detected in many" 34 "testis cancer: 355.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 19 "testis cancer: 264.4" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 4 Nucleoplasm Cytosol "CAB025600: , CAB026380: , CAB079773: AB_2687916, HPA058267: AB_2683659" "unprognostic (3.25e-2)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-2)" "unprognostic (2.11e-2)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.59e-1)" "unprognostic (9.27e-2)" "unprognostic (2.27e-2)" "unprognostic (4.79e-2)" "unprognostic (1.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.35e-1)" "unprognostic (3.86e-2)" "prognostic favorable (2.04e-5)" PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 271.0;liver: 576.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 419.1;Hepatocytes: 977.8;Proximal enterocytes: 1232.0;Proximal tubular cells: 457.0;Suprabasal keratinocytes: 857.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 6.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 6.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 2400000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favorable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 446.7;Sertoli cells: 1966.4;Smooth muscle cells: 1441.0" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 878.5" "Adipose subcutaneous - Endothelial cells, Kidney - Fibroblasts, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 47: Endothelial cells - Vasculature" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 1100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 12 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavorable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favorable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34049388 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Testis - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 37: Glandular & Luminal cells - Unknown function" 25 Cytosol "HPA021684: AB_2211887" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "prognostic favorable (8.59e-4)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "prognostic favorable (1.95e-4)" "unprognostic (8.06e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-1)" "unprognostic (8.77e-2)" ZNF75D "D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28" ENSG00000186376 "Zinc finger protein 75D" P51815 X 135248920-135344109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 158.8;Late spermatids: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004705 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA004705: AB_1080749" "unprognostic (1.56e-3)" "unprognostic (7.96e-3)" "unprognostic (3.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.00e-2)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (9.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "prognostic favorable (7.42e-5)" QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 220.1;Intestinal goblet cells: 179.2;Paneth cells: 215.4;Proximal enterocytes: 256.8;Undifferentiated cells: 225.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 143.4;skin 1: 166.8" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 4290.5" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.5;testis cancer: 6.6" "Adipose visceral - Neutrophils, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021238, HPA062245, CAB069927" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 72: Alveolar cells - Lung function" 10 Nucleoplasm Vesicles "CAB069927: AB_1082966, HPA021238: AB_1845475, HPA062245: AB_2684724" "unprognostic (2.19e-1)" "unprognostic (9.20e-3)" "unprognostic (2.67e-2)" "unprognostic (2.84e-2)" "unprognostic (2.62e-1)" "unprognostic (7.75e-2)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.93e-1)" "unprognostic (8.46e-2)" "unprognostic (2.40e-2)" "unprognostic (3.04e-2)" "unprognostic (7.35e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.74e-2)" RACGAP1 "CYK4, MgcRacGAP" ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.4;lymphoid tissue: 41.9;testis: 44.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 36.9;Erythroid cells: 43.7;Extravillous trophoblasts: 50.9;Oocytes: 33.1;Spermatocytes: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 32: Basophils - Transcription" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 13 Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" ABR MDB ENSG00000159842 "ABR activator of RhoGEF and GTPase" Q12979 17 1003519-1229738 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.9;Late spermatids: 159.3;Microglial cells: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 9.0" "Lineage enriched" "Detected in single" 15 "granulocytes: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053618, HPA054824" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 36: Late spermatids - Unknown function" Cytosol Nucleoplasm "HPA053618: AB_2682208, HPA054824: AB_2682616" "unprognostic (1.69e-1)" "prognostic favorable (4.03e-4)" "unprognostic (1.58e-1)" "unprognostic (1.94e-3)" "unprognostic (1.12e-1)" "unprognostic (2.20e-2)" "unprognostic (4.99e-2)" "unprognostic (7.53e-2)" "unprognostic (1.91e-1)" "unprognostic (9.61e-2)" "unprognostic (7.20e-3)" "unprognostic (4.43e-3)" "prognostic favorable (2.21e-4)" "unprognostic (2.27e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-1)" "unprognostic (1.74e-2)" ALAS1 "ALAS, ALAS-H, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 697.9;bone marrow: 174.6;liver: 532.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 155.0;granulocytes: 154.0;Hepatocytes: 267.6;Syncytiotrophoblasts: 360.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 234.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 234.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 43: Hepatocytes - Metabolism" 36 Mitochondria Nucleoplasm "CAB017498: AB_2225629, HPA035860: AB_10672992" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.98e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (5.64e-2)" "prognostic favorable (6.06e-7)" "unprognostic (8.45e-2)" "unprognostic (3.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" ALX4 "FPP, KIAA1788, PFM, PFM2" ENSG00000052850 "ALX homeobox 4" Q9H161 11 44260440-44310139 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.8;choroid plexus: 1.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.2;Fibroblasts: 3.1;Late spermatids: 1.2;Leydig cells: 4.4;Microglial cells: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 20.7" "Region enriched" "Detected in some" 8 "olfactory bulb: 9.0" "Region enriched" "Detected in single" 28 "olfactory bulb: 12.1" HPA001903 Supported Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 30: Granulocytes - Unknown function" 2 Nucleoplasm "HPA001903: AB_2666495" "unprognostic (7.56e-5)" "unprognostic (1.69e-1)" "unprognostic (5.40e-2)" "unprognostic (2.74e-1)" "unprognostic (7.24e-3)" "unprognostic (2.63e-4)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-4)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-1)" "unprognostic (1.34e-6)" "unprognostic (3.62e-2)" "unprognostic (2.85e-1)" "unprognostic (2.02e-3)" "unprognostic (2.03e-1)" APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 92.7;lymphoid tissue: 47.2;urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 91.7;Hofbauer cells: 132.3;Macrophages: 73.3;monocytes: 307.7;Serous glandular cells: 81.6;Squamous epithelial cells: 55.5;Suprabasal keratinocytes: 121.2" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1008.2" "Lineage enriched" "Detected in many" 8 "monocytes: 1008.2" "Cancer enriched" "Detected in single" 9 "head and neck cancer: 5.4" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 1 Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 91 "kidney: 373.4;seminal vesicle: 205.2" "Cell type enriched" "Detected in some" 17 "Collecting duct cells: 3224.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;Gastric cancer: 1.2" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" 33 "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "kidney: 51.2" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Club cells: 1.5;Collecting duct cells: 1.9;Distal tubular cells: 3.1;Ionocytes: 5.5;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.5" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 264 "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 560.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 12 "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827873 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 98.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 8 "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" BRD2 "BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3" ENSG00000204256 "Bromodomain containing 2" P25440 6 32968594-32981505 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042816, HPA074612" Approved Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 80: Non-specific - Transcription" 15 "Nucleoplasm, Nuclear speckles" "HPA042816: AB_10794766, HPA074612: " "unprognostic (2.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.45e-1)" "unprognostic (9.89e-2)" "unprognostic (5.03e-2)" "unprognostic (2.54e-1)" "unprognostic (6.85e-3)" "unprognostic (1.39e-2)" "unprognostic (1.95e-2)" "unprognostic (3.42e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "unprognostic (1.44e-2)" BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748019 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 19 "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" BTRC "beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1" ENSG00000166167 "Beta-transducin repeat containing E3 ubiquitin protein ligase" Q9Y297 10 101354033-101557321 "Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 104.0;Excitatory neurons: 148.8;Inhibitory neurons: 138.3;Oligodendrocyte precursor cells: 172.2;Oligodendrocytes: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031156, CAB032986" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 76: Oligodendrocyte precursor - Unknown function" 37 Nucleoplasm "Plasma membrane, Cytosol" "CAB032986: AB_2243598, HPA031156: AB_2673764" "unprognostic (1.43e-1)" "unprognostic (2.35e-2)" "unprognostic (8.88e-2)" "unprognostic (2.09e-1)" "unprognostic (3.55e-1)" "unprognostic (2.73e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.22e-1)" "unprognostic (1.59e-2)" "unprognostic (8.80e-3)" "unprognostic (5.05e-1)" "unprognostic (2.81e-3)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (2.23e-1)" CA5A "CA5, CAV, CAVA" ENSG00000174990 "Carbonic anhydrase 5A" P35218 16 87881546-87936580 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "liver: 23.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 37.0" "Cancer enriched" "Detected in single" 26 "liver cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.1;Gastric cancer: 1.6;liver cancer: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (1.91e-1)" "unprognostic (8.64e-3)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (2.49e-2)" "unprognostic (2.96e-1)" "unprognostic (8.39e-3)" "unprognostic (3.50e-3)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (6.55e-2)" "unprognostic (4.23e-2)" "unprognostic (7.99e-3)" "unprognostic (1.77e-1)" "unprognostic (5.03e-3)" "unprognostic (3.37e-2)" "unprognostic (2.76e-2)" CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 219.3" "Cell type enhanced" "Detected in many" "Adipocytes: 286.6;Alveolar cells type 1: 672.1;Basal keratinocytes: 318.9;Basal respiratory cells: 313.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 433 "granulocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB013488: AB_2533493, HPA044810: AB_2679098" "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 616.5" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 51.6;Fibroblasts: 59.0;Langerhans cells: 70.9;Smooth muscle cells: 151.4" "Cancer enhanced" "Detected in all" "testis cancer: 118.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "breast cancer: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" Chemokine NA NA 195000 63000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA067758: AB_2685897" "prognostic favorable (2.88e-5)" "prognostic favorable (9.91e-6)" "unprognostic (8.25e-3)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (8.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (7.98e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 238.0;Langerhans cells: 274.7;Melanocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 35.8;intestine: 18.8" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 179.3;Schwann cells: 672.0" "Cancer enriched" "Detected in some" 21 "melanoma: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Sarcoma: 4.8;skin cancer: 12.4" "Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 320000 "Cluster 30: Heart muscle - Heart development" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA056332: AB_2683102" "unprognostic (1.63e-2)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (3.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.39e-2)" "unprognostic (9.33e-2)" "unprognostic (2.25e-2)" "unprognostic (4.58e-3)" "unprognostic (8.16e-3)" "unprognostic (8.21e-2)" "unprognostic (1.56e-5)" CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 39.7" "Group enriched" "Detected in some" 7 "Distal enterocytes: 296.7;Enteroendocrine cells: 153.7;Intestinal goblet cells: 199.1;Paneth cells: 216.3;Proximal enterocytes: 243.1;Undifferentiated cells: 178.9" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 63.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 73.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA049580" Enhanced Enhanced Nucleoplasm NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 2 Nucleoplasm "CAB002221: AB_563649, HPA045669: AB_2679413, HPA049580: AB_2680823" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.92e-1)" "unprognostic (8.11e-3)" "unprognostic (4.19e-6)" "unprognostic (1.73e-4)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (5.51e-2)" "unprognostic (6.07e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.2;Early spermatids: 203.9;Late spermatids: 319.9;Rod photoreceptor cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606, HPA061504" Uncertain Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Retina & Testis - Cilium" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 4 Centrosome "Nucleoplasm, Vesicles" "HPA037605: AB_10672908, HPA037606: AB_10672498, HPA061504: AB_2732665" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (1.90e-1)" "prognostic favorable (5.93e-4)" "unprognostic (6.54e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (7.93e-2)" CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Mitotic cells (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 9: Endometrial stromal cells - Transcription" 18 Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2;retina: 36.7;skeletal muscle: 43.4;tongue: 32.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 74.0;Cone photoreceptor cells: 142.7;Excitatory neurons: 44.1;Horizontal cells: 57.9;Inhibitory neurons: 51.7;Oligodendrocytes: 71.3;Oocytes: 44.8;Rod photoreceptor cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.7;memory B-cell: 1.0;naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 15.9;kidney: 23.2" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 68.3" "Cancer enriched" "Detected in single" 7 "renal cancer: 1.5" "Region enhanced" "Detected in some" "choroid plexus: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 3.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" 5 "HPA048976: AB_2680582" "unprognostic (1.68e-1)" "unprognostic (3.06e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-2)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-4)" "unprognostic (6.73e-2)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (9.03e-4)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" CLEC1A "CLEC-1, CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 48.9;placenta: 47.4" "Cell type enhanced" "Detected in some" "Adipocytes: 47.9;Cytotrophoblasts: 53.0;Endothelial cells: 36.5;Extravillous trophoblasts: 65.2;Syncytiotrophoblasts: 52.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "testis cancer: 5.1" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "spinal cord: 8.4" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 13 "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" CLEC2B "AICL, CLECSF2, HP10085" ENSG00000110852 "C-type lectin domain family 2 member B" Q92478 12 9852369-9869386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 111.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 355.9;monocytes: 704.6;NK-cells: 407.1;T-cells: 307.5" "Cancer enhanced" "Detected in all" "cervical cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 222.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.0" "Low region specificity" "Detected in all" HPA008194 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA008194: AB_1078533" "unprognostic (3.14e-2)" "unprognostic (4.27e-2)" "unprognostic (2.14e-2)" "unprognostic (9.69e-3)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" "unprognostic (5.99e-2)" "unprognostic (4.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.50e-1)" "prognostic unfavorable (5.64e-13)" "unprognostic (8.09e-2)" "unprognostic (7.12e-3)" "unprognostic (5.70e-2)" "unprognostic (2.79e-1)" CLEC4A "CD367, CLECSF6, DCIR, DDB27, hDCIR" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 21.3;lymphoid tissue: 26.1" "Group enriched" "Detected in some" 4 "Hofbauer cells: 14.1;Kupffer cells: 28.8;Langerhans cells: 31.2;Macrophages: 35.2;monocytes: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 227.9;classical monocyte: 333.0;intermediate monocyte: 198.7;myeloid DC: 328.2;neutrophil: 300.4;non-classical monocyte: 130.7" "Group enriched" "Detected in all" 13 "dendritic cells: 328.2;granulocytes: 300.4;monocytes: 333.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" "HPA007842: AB_1078534" "unprognostic (9.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.13e-2)" "unprognostic (2.69e-1)" "unprognostic (9.34e-2)" "unprognostic (5.49e-2)" "unprognostic (8.22e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.42e-3)" "unprognostic (1.42e-1)" "unprognostic (1.35e-2)" "unprognostic (3.05e-1)" "unprognostic (9.79e-2)" CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 64.0" "Cell type enhanced" "Detected in some" "Hofbauer cells: 8.0;Kupffer cells: 12.0;Macrophages: 10.1;monocytes: 2.6" "Cancer enriched" "Detected in single" 50 "testis cancer: 11.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "classical monocyte: 57.4;neutrophil: 99.4" "Group enriched" "Detected in many" 32 "granulocytes: 99.4;monocytes: 57.4" "Cancer enhanced" "Detected in some" "lymphoma: 3.2;testis cancer: 8.4" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 3 "HPA004906: AB_1078535" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.39e-1)" "unprognostic (3.84e-2)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.81e-1)" "unprognostic (7.91e-5)" "unprognostic (1.12e-2)" "unprognostic (8.57e-2)" "unprognostic (7.89e-2)" "unprognostic (2.18e-1)" CLEC4E "CLECSF9, MINCLE" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;lymphoid tissue: 51.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 39.5;Hofbauer cells: 52.8;Kupffer cells: 170.0;Macrophages: 104.7;monocytes: 203.2" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 129.3;neutrophil: 451.9" "Group enriched" "Detected in many" 17 "granulocytes: 451.9;monocytes: 129.3" "Group enriched" "Detected in some" 8 "Kidney cancer: 30.8;ovarian cancer: 9.6" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 3 "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 101.7;Extravillous trophoblasts: 261.5;Hofbauer cells: 120.2;Sertoli cells: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 4: Extravillous trophoblasts - Unknown function" 19 Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 4 Mitochondria "Nucleoplasm, Cytosol" "HPA043738: AB_10795041" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (7.51e-2)" "unprognostic (7.38e-2)" "unprognostic (4.51e-1)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (5.82e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 101.0" "Cell type enhanced" "Detected in many" "Adipocytes: 78.1;Fibroblasts: 73.2;Leydig cells: 87.4;Melanocytes: 101.4;Sertoli cells: 40.8;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Neuroblastoma: 103.1;skin cancer: 110.9" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Fibroblasts - ECM organization" 4 "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1667.6" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 1605.5" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.6;liver cancer: 1.4;prostate cancer: 1.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 757 "epididymis: 1270.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Distal tubular cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA045292: AB_2679288" DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "HPA045292: AB_2679288" DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 179.8;Oligodendrocyte precursor cells: 135.8;Oligodendrocytes: 590.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 51: Oligodendrocytes - Unknown function" "Endoplasmic reticulum" "HPA038472: AB_2676033, HPA046133: AB_2679551, HPA056045: AB_2683019" "prognostic unfavorable (2.60e-4)" "unprognostic (2.85e-2)" "unprognostic (3.67e-3)" "unprognostic (2.86e-2)" "unprognostic (9.56e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-2)" "unprognostic (1.94e-2)" "unprognostic (2.67e-2)" "unprognostic (9.57e-3)" "unprognostic (3.90e-2)" "unprognostic (4.29e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-3)" DRG2 ENSG00000108591 "Developmentally regulated GTP binding protein 2" P55039 17 18087892-18107970 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007716 Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 7 "Vesicles, Cytosol" Nucleoplasm "HPA007716: AB_1078705" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.26e-3)" "unprognostic (7.86e-2)" "unprognostic (8.85e-2)" "unprognostic (5.72e-2)" "unprognostic (8.49e-2)" "unprognostic (1.25e-1)" "unprognostic (2.88e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (3.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.1;pituitary gland: 4.0;retina: 1.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1045.7;Oligodendrocyte precursor cells: 4106.7" "Cancer enriched" "Detected in single" 14 "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "Golgi apparatus" "HPA019324: AB_2670118, HPA057493: " "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (9.98e-2)" "unprognostic (5.49e-4)" "unprognostic (1.78e-1)" "unprognostic (9.58e-2)" "unprognostic (7.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (2.12e-2)" "unprognostic (2.00e-3)" "unprognostic (2.17e-2)" "unprognostic (2.29e-1)" "unprognostic (8.75e-2)" "unprognostic (5.46e-3)" DYNC1I2 "DIC74, DNCI2" ENSG00000077380 "Dynein cytoplasmic 1 intermediate chain 2" Q13409 2 171687409-171750158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transport" "Motor protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033836, HPA040619, HPA053987" Supported Supported "Nucleoli,Endoplasmic reticulum,Microtubules,Cytosol" NA NA 82000 "Cluster 32: Basophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 6 "Endoplasmic reticulum, Cytosol" "Nucleoli, Microtubules" "CAB033836: AB_2093633, HPA040619: AB_2677045, HPA053987: AB_2682334" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-2)" "unprognostic (8.15e-2)" "unprognostic (8.90e-2)" "unprognostic (1.37e-3)" "unprognostic (2.51e-3)" "unprognostic (6.30e-3)" "unprognostic (1.23e-1)" "unprognostic (1.89e-2)" "unprognostic (1.40e-2)" "unprognostic (4.19e-1)" "prognostic favorable (8.04e-4)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (1.35e-3)" "unprognostic (6.42e-2)" EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 27.1;fallopian tube: 14.2" "Cell type enhanced" "Detected in many" "Astrocytes: 30.3;Ciliated cells: 64.3;Early spermatids: 92.6;Late spermatids: 23.4;Oocytes: 51.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 36.5" "Group enriched" "Detected in some" 7 "basophil: 16.3;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.3;NK-cells: 5.8" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.2;Leukemia: 1.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 42: Ciliated cells - Cilium assembly" 79 "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "HPA034492: AB_10671227" "unprognostic (1.93e-1)" "unprognostic (7.80e-3)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (6.83e-3)" "unprognostic (5.07e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (7.89e-2)" "unprognostic (1.06e-1)" "unprognostic (6.13e-4)" "unprognostic (1.64e-3)" "unprognostic (4.97e-2)" ENKUR "C10orf63, CFAP106, enkurin, MGC26778" ENSG00000151023 "Enkurin, TRPC channel interacting protein" Q8TC29 10 24981979-25062279 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.3;choroid plexus: 16.2;fallopian tube: 42.2" "Group enriched" "Detected in many" 4 "Ciliated cells: 164.9;Early spermatids: 85.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 3.1;glioma: 4.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037593, HPA037594, HPA061503" Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Ciliated cells - Cilium assembly" 9 "HPA037593: AB_10672387, HPA037594: AB_2675568, HPA061503: AB_2684543" "unprognostic (2.33e-3)" "unprognostic (4.86e-2)" "unprognostic (1.13e-2)" "unprognostic (6.52e-3)" "unprognostic (3.31e-2)" "unprognostic (2.91e-2)" "unprognostic (1.38e-2)" "unprognostic (7.35e-2)" "unprognostic (1.18e-1)" "unprognostic (8.69e-2)" "unprognostic (6.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-6)" "unprognostic (3.94e-1)" "unprognostic (3.35e-2)" "unprognostic (3.45e-3)" "unprognostic (8.43e-3)" EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 87 "epididymis: 319.7;testis: 81.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 21.4;Granulosa cells: 31.7;Late spermatids: 22.9;Sertoli cells: 119.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067335 Supported "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "HPA067335: " "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.08e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (2.00e-2)" ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 35.8" "Cell type enriched" "Detected in some" 35 "Syncytiotrophoblasts: 667.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "testis cancer: 35.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 21 "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 188.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 162.0;Hepatocytes: 249.3;Kupffer cells: 167.7;Proximal enterocytes: 181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 7 "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" EXOSC3 "CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p" ENSG00000107371 "Exosome component 3" Q9NQT5 9 37759234-37832117 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 123.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020485 Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 21: Testis - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 9 Nucleoplasm "HPA020485: AB_10960685" "unprognostic (7.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (3.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (1.71e-3)" "unprognostic (5.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.20e-2)" "unprognostic (9.25e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 129.4" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 257.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 28: Neuronal - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 Nucleoplasm "HPA005478: AB_1848340, HPA077684: AB_2732356" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" FAM111B CANP ENSG00000189057 "FAM111 trypsin like peptidase B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 15.7;Basal keratinocytes: 9.8;Oocytes: 19.9;Plasma cells: 10.3;Schwann cells: 9.7;Undifferentiated cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 14: Non-specific - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 4 Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 512.0;Plasma cells: 191.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 20.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 7 "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" FCGR3B "CD16, CD16b, FCG3, FcgammaRIIIb, FCGR3, FcRIIIb" ENSG00000162747 "Fc gamma receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.5;lymphoid tissue: 79.0" "Cell type enriched" "Detected in some" 7 "Serous glandular cells: 28.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "cerebral cortex: 11.0;pons: 4.2" "Immune cell enriched" "Detected in many" 356 "neutrophil: 6077.6" "Lineage enriched" "Detected in many" 356 "granulocytes: 6077.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Secreted to blood" Receptor NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" GABRB1 ENSG00000163288 "Gamma-aminobutyric acid type A receptor subunit beta1" P18505 4 46993723-47426447 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.3;heart muscle: 3.5" "Group enriched" "Detected in some" 15 "Astrocytes: 878.4;Excitatory neurons: 425.6;Inhibitory neurons: 485.1;Oligodendrocyte precursor cells: 250.5" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" "unprognostic (3.11e-2)" "unprognostic (7.56e-3)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (4.98e-3)" "unprognostic (8.16e-3)" "unprognostic (6.22e-2)" "unprognostic (2.72e-2)" "unprognostic (2.34e-1)" GCDH "ACAD5, GCD" ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 125.6;Proximal tubular cells: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favorable (7.28e-5)" "prognostic favorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favorable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oocytes: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 820000 "Cluster 1: T-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 44: Oocytes - Unknown function" 2 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.1;choroid plexus: 75.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.3;Ciliated cells: 50.4;Excitatory neurons: 35.5;Horizontal cells: 71.8;Inhibitory neurons: 31.5;Muller glia cells: 46.1" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.5" "Group enriched" "Detected in many" 6 "granulocytes: 17.5;monocytes: 6.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.0" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" GPR32 RVDR1 ENSG00000142511 "G protein-coupled receptor 32" O75388 19 50770464-50771732 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 32 "parathyroid gland: 56.2" "Group enriched" "Detected in some" 29 "Extravillous trophoblasts: 6.3;Syncytiotrophoblasts: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "testis cancer: 2.9" "Not detected" "Not detected" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (4.77e-1)" GRWD1 "GRWD, RRB1, WDR28" ENSG00000105447 "Glutamate rich WD repeat containing 1" Q9BQ67 19 48445841-48457022 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042643, HPA055680" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042643: AB_10795510, HPA055680: AB_2682884" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (4.99e-2)" "unprognostic (1.00e-1)" "unprognostic (3.46e-1)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.71e-2)" "unprognostic (5.68e-2)" "unprognostic (2.69e-2)" "unprognostic (7.70e-2)" "unprognostic (2.83e-2)" "unprognostic (8.10e-2)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.02e-1)" "unprognostic (5.07e-2)" GTF2H3 "BTF2, P34, TFIIH" ENSG00000111358 "General transcription factor IIH subunit 3" Q13889 12 123633739-123662604 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004844, HPA053562" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 3 Nucleoplasm "HPA004844: AB_2667265, HPA053562: AB_2682191" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.02e-2)" "unprognostic (6.13e-3)" "unprognostic (2.29e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.72e-8)" "unprognostic (1.02e-1)" "unprognostic (1.22e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-1)" "unprognostic (1.10e-1)" "unprognostic (5.68e-3)" "unprognostic (4.71e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (2.80e-2)" HARS1 "HARS, HisRS, USH3B" ENSG00000170445 "Histidyl-tRNA synthetase 1" P12081 5 140673035-140691537 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol NA NA 190000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Cytosol "HPA036539: AB_10669796" "unprognostic (9.35e-2)" "unprognostic (9.95e-2)" "unprognostic (1.62e-3)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.36e-1)" HDAC3 "HD3, KDAC3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636849 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Langerhans cells - Innate immune response" 19 Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: AB_2681708" "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favorable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" HOXB13 ENSG00000159184 "Homeobox B13" Q92826 17 48724763-48728750 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 39.9;prostate: 79.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 154.6;Enteroendocrine cells: 92.0;Intestinal goblet cells: 61.9;Paneth cells: 56.1;Prostatic glandular cells: 209.8;Undifferentiated cells: 50.2" "Cancer enriched" "Detected in many" 17 "prostate cancer: 187.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 151.6" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004438, HPA062852, HPA065019" Enhanced Enhanced Nucleoplasm NA NA "Cluster 45: Intestine - Digestion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 3 Nucleoplasm "CAB004438: AB_627744, HPA062852: AB_2684880, HPA065019: AB_2685406" "unprognostic (4.81e-2)" "unprognostic (2.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.33e-2)" "unprognostic (5.85e-3)" "unprognostic (1.88e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (1.17e-2)" "unprognostic (6.65e-2)" "unprognostic (1.74e-1)" "unprognostic (4.27e-2)" "unprognostic (4.73e-11)" "unprognostic (1.39e-2)" "unprognostic (4.50e-2)" "unprognostic (1.12e-1)" HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452465-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 222.2;Hepatocytes: 235.5;Oligodendrocytes: 206.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 68.5" "Group enriched" "Detected in all" 4 "dendritic cells: 20.1;granulocytes: 68.5;monocytes: 25.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Basal prostatic cells - Lipid metabolism" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" HTR3E ENSG00000186038 "5-hydroxytryptamine receptor 3E" A5X5Y0 3 184097064-184106995 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 1.0;Oligodendrocyte precursor cells: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049764 Enhanced NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA049764: AB_2680869" "unprognostic (4.12e-2)" "unprognostic (5.86e-2)" "unprognostic (2.15e-1)" "unprognostic (4.57e-4)" "unprognostic (3.61e-3)" "unprognostic (1.15e-1)" "unprognostic (3.16e-1)" "unprognostic (4.47e-1)" "unprognostic (3.32e-1)" "unprognostic (2.67e-1)" "unprognostic (4.16e-2)" IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 34 "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" IFT20 ENSG00000109083 "Intraflagellar transport 20" Q8IY31 17 28328325-28335489 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021376 Approved Approved Microtubules NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Mixed function" 24 Microtubules "HPA021376: AB_1851460" "unprognostic (1.29e-1)" "unprognostic (2.35e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (8.65e-4)" "unprognostic (1.13e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (8.02e-2)" "unprognostic (4.86e-3)" "unprognostic (2.42e-1)" "unprognostic (2.48e-2)" "unprognostic (6.19e-3)" "prognostic unfavorable (5.09e-7)" "unprognostic (1.67e-1)" "unprognostic (2.29e-1)" "unprognostic (2.59e-2)" "unprognostic (4.71e-3)" IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 23.5;lymphoid tissue: 18.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 37.8;dendritic cells: 55.4;granulocytes: 126.7;Langerhans cells: 32.8;NK-cells: 47.0;Schwann cells: 26.2;T-cells: 36.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007615 Approved Approved Mitochondria Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 1 Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 59.9;kidney: 122.8;lung: 157.1;placenta: 193.2" "Cell type enriched" "Detected in many" 6 "granulocytes: 1024.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.4;eosinophil: 29.4" "Lineage enriched" "Detected in single" 73 "granulocytes: 38.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 24.0;pancreatic cancer: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" Receptor NA NA 19100000 3100000 "Cluster 41: Basophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 1 "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" IL1RL2 "IL-36R, IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 6.1;Excitatory neurons: 9.4;Glandular and luminal cells: 6.6;Langerhans cells: 7.8;monocytes: 5.9;Suprabasal keratinocytes: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" NA NA "Cluster 13: Skin - Cornification" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" ING5 "FLJ23842, p28ING5" ENSG00000168395 "Inhibitor of growth family member 5" Q8WYH8 2 241687085-241729478 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042685 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" 21 "HPA042685: AB_10797507" "unprognostic (1.87e-2)" "unprognostic (3.66e-1)" "unprognostic (1.65e-3)" "unprognostic (9.15e-3)" "unprognostic (1.79e-1)" "unprognostic (1.07e-3)" "prognostic unfavorable (2.86e-5)" "unprognostic (8.25e-2)" "unprognostic (2.30e-2)" "unprognostic (7.87e-2)" "prognostic favorable (1.60e-4)" "unprognostic (2.15e-1)" "unprognostic (5.88e-2)" "unprognostic (8.43e-2)" "unprognostic (5.01e-2)" "unprognostic (5.90e-2)" "unprognostic (4.74e-3)" ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1466.0;Late spermatids: 948.7;Proximal tubular cells: 1197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 39: Non-specific - Basic cellular processes" 16 "Mitochondria, Cytosol" "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 270000 "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Monocytes - Innate immune response" 4 Vesicles "HPA041802: AB_10794491, HPA054532: AB_2682517" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-3)" "unprognostic (2.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "prognostic favorable (4.55e-4)" "unprognostic (1.64e-2)" "unprognostic (7.88e-3)" "unprognostic (8.43e-3)" "prognostic favorable (8.88e-4)" ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported Nucleoplasm,Cytosol NA NA 120000 "Cluster 13: Non-specific - Mitochondria" "Cluster 18: Non-specific - Ribosome" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA022824: AB_1851960, HPA073963: " "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (1.53e-2)" "prognostic unfavorable (2.54e-5)" "unprognostic (1.11e-2)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-2)" "unprognostic (8.34e-2)" "unprognostic (3.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 252.2" "Cancer enhanced" "Detected in all" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 71.9" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "Nucleoplasm, Mitochondria" "CAB069890: AB_10000529, HPA063889: AB_2685143" "unprognostic (5.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (4.87e-3)" "unprognostic (6.35e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (3.26e-3)" "unprognostic (7.04e-2)" "unprognostic (4.48e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113111-42121367 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 6 "HPA048958: AB_2680571" "unprognostic (1.71e-1)" "unprognostic (9.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (9.07e-2)" "unprognostic (1.91e-3)" "unprognostic (3.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "prognostic favorable (3.57e-4)" "unprognostic (2.78e-2)" "prognostic unfavorable (1.41e-8)" "unprognostic (3.97e-2)" "unprognostic (2.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.29e-3)" KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" KCNA6 "HBK2, Kv1.6, PPP1R96" ENSG00000151079 "Potassium voltage-gated channel subfamily A member 6" P17658 12 4809334-4813318 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 9.4" "Group enriched" "Detected in some" 8 "Astrocytes: 13.3;Excitatory neurons: 26.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 2.3;testis cancer: 7.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076475 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" Vesicles "HPA076475: " KCNRG ENSG00000198553 "Potassium channel regulator" Q8N5I3 13 50015254-50020922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "fallopian tube: 34.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 58.1;Early spermatids: 21.6;Ionocytes: 9.2;Late spermatids: 11.4;Spermatocytes: 9.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001027 Uncertain Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 59: Fallopian tube - Tissue development" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 1 Vesicles "HPA001027: " "unprognostic (1.85e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-2)" "prognostic favorable (2.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.39e-3)" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (1.71e-1)" "unprognostic (5.91e-1)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (4.69e-2)" "unprognostic (1.52e-1)" "unprognostic (9.16e-2)" KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119263-67258082 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (7.43e-2)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (8.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (2.84e-1)" "unprognostic (4.46e-1)" "unprognostic (2.04e-3)" "unprognostic (3.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "unprognostic (9.45e-3)" KIF27 DKFZp434D0917 ENSG00000165115 "Kinesin family member 27" Q86VH2 9 83834099-83921465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 63.7;Early spermatids: 155.1;Late spermatids: 87.7;Spermatocytes: 58.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 16.2" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" 2 "unprognostic (9.75e-2)" "unprognostic (3.86e-2)" "unprognostic (1.46e-1)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (2.83e-3)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" "unprognostic (3.86e-3)" "unprognostic (9.81e-2)" "unprognostic (1.94e-1)" "unprognostic (2.55e-1)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (1.85e-1)" "unprognostic (2.01e-1)" KLF7 UKLF ENSG00000118263 "KLF transcription factor 7" O75840 2 207074137-207173856 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 88.4;monocytes: 86.1;Oligodendrocytes: 149.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 85 "prostate: 546.6" "Cell type enriched" "Detected in some" 358 "Prostatic glandular cells: 6422.7" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 134 "prostate cancer: 207.3" "Prostate - Prostate glandular cells" HPA000764 Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Neuronal - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.5" "Group enriched" "Detected in some" 23 "NK-cells: 225.5;T-cells: 104.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 229.7;NK-cell: 368.5" "Group enriched" "Detected in many" 47 "NK-cells: 368.5;T-cells: 229.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 42 "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 12670.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 6357.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 5 "Bladder cancer: 10.9;Esophageal cancer: 23.0;head and neck cancer: 17.4" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 11: T-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 32 "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 298.6;esophagus: 997.0;skin 1: 349.5;vagina: 474.5" "Group enriched" "Detected in many" 8 "Basal keratinocytes: 5602.9;Serous glandular cells: 2384.9;Suprabasal keratinocytes: 9130.9" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 9.8;cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 107.9;head and neck cancer: 324.1" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 46 "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 864.1;salivary gland: 786.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 6850.6;Club cells: 5440.4;Distal enterocytes: 7654.8;Extravillous trophoblasts: 8032.7;Proximal enterocytes: 8878.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 65 "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4511.5" "Cell type enriched" "Detected in some" 30 "Suprabasal keratinocytes: 130.9" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" CAB037321 Enhanced NA NA 9700000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 82: Skin - Keratinization" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 11 "CAB037321: " "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 629.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2017.7;Enteroendocrine cells: 335.6;Intestinal goblet cells: 454.6;Paneth cells: 1576.2;Proximal enterocytes: 1249.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 159.5;stomach cancer: 52.7;urothelial cancer: 99.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.5;colorectal cancer: 95.3;liver cancer: 50.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 30000000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 32 "Intermediate filaments, Cytosol" "CAB000032: AB_2133718, HPA024309: AB_1852220, HPA024684: AB_1852222, HPA027236: AB_1852224" "unprognostic (3.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-3)" "unprognostic (5.12e-2)" "unprognostic (2.66e-3)" "prognostic unfavorable (7.05e-4)" "unprognostic (2.63e-2)" "unprognostic (4.87e-3)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.71e-2)" "unprognostic (6.30e-2)" "unprognostic (7.27e-2)" KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 173.0;lymphoid tissue: 74.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Basal prostatic cells: 11.1;Cytotrophoblasts: 6.2;Fibroblasts: 3.2;Leydig cells: 3.0;Serous glandular cells: 4.4;Syncytiotrophoblasts: 4.2" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 316 "Rhabdoid: 170.8" "Skin - Keratinocyte (other), Stomach - Fibroblasts" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 26 "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 108.8" "Group enriched" "Detected in some" 5 "Early spermatids: 4.1;Late spermatids: 10.5;Spermatogonia: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 106 "Rhabdoid: 61.0" "Skin - Inner root sheath cells, Testis - Late spermatids" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 9.5;hippocampal formation: 6.3" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 13: Skin - Cornification" "Cluster 5: Rhabdoid - Unknown function" "Cluster 11: Late spermatids - Unknown function" 22 Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" KRT27 KRT25C ENSG00000171446 "Keratin 27" Q7Z3Y8 17 40776808-40782550 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "skin 1: 69.2" "Cell type enriched" "Detected in some" 5 "Melanocytes: 13.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.9;thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "Rhabdoid: 29.8" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "hippocampal formation: 105.3" HPA055114 Enhanced NA NA "Cluster 82: Skin - Keratinization" "Cluster 5: Rhabdoid - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" 113 "HPA055114: AB_2682700" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" "unprognostic (2.18e-1)" "unprognostic (5.75e-4)" "unprognostic (5.11e-2)" "unprognostic (3.08e-2)" "unprognostic (8.41e-2)" "unprognostic (4.16e-1)" "unprognostic (1.53e-1)" "unprognostic (4.90e-1)" "unprognostic (1.56e-1)" "unprognostic (5.64e-3)" KRT28 KRT25D ENSG00000173908 "Keratin 28" Q7Z3Y7 17 40792196-40799959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 11.3" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.7" "Cancer enhanced" "Detected in some" "cervical cancer: 0.6;endometrial cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 815 "Rhabdoid: 81.4" "Skin - Inner root sheath cells" "Region enriched" "Detected in single" 6 "cerebellum: 3.2" "Low region specificity" "Detected in all" HPA066890 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 5: Rhabdoid - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" 15 "HPA066890: AB_2685742" KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 275.4" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 32.4;Basal squamous epithelial cells: 18.4;Glandular and luminal cells: 11.6;Oocytes: 12.5;Squamous epithelial cells: 16.7;Suprabasal keratinocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "HPA049550, HPA055194" Enhanced NA NA 440000000 "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 284 "HPA049550: AB_2680813, HPA055194: AB_2682733" "unprognostic (3.92e-2)" "unprognostic (3.50e-1)" "unprognostic (3.30e-1)" "unprognostic (5.51e-2)" "unprognostic (7.71e-2)" "unprognostic (4.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (4.07e-1)" "unprognostic (4.26e-2)" "unprognostic (1.65e-1)" KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.7;skin 1: 18.9" "Group enriched" "Detected in some" 5 "Basal squamous epithelial cells: 18.2;Oocytes: 11.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 13: Skin - Cornification" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377669-41382306 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 64.5" "Cell type enriched" "Detected in some" 8 "Late spermatids: 17.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 7.1" "Skin - Hair cortex cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 13: Skin - Cornification" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 201 "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" KRT35 "Ha-5, KRTHA5" ENSG00000197079 "Keratin 35" Q92764 17 41476710-41481151 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 56.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025750, HPA078713" Enhanced Approved "Intermediate filaments" NA NA 220000000 "Cluster 13: Skin - Cornification" "Cluster 32: Non-specific - Cell proliferation" 69 "Intermediate filaments" "HPA025750: , HPA078713: " KRT36 KRTHA6 ENSG00000126337 "Keratin 36" O76013 17 41486136-41492546 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.3;skin 1: 1.7" "Group enriched" "Detected in some" 26 "Oocytes: 263.9;Suprabasal keratinocytes: 383.1" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 180000000 "Cluster 71: Thymus - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (4.39e-2)" "unprognostic (2.24e-3)" "unprognostic (9.85e-2)" "unprognostic (4.66e-1)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (7.19e-2)" "unprognostic (8.24e-2)" "unprognostic (8.50e-2)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (1.49e-1)" "unprognostic (7.11e-2)" KRT37 KRTHA7 ENSG00000108417 "Keratin 37" O76014 17 41420547-41424585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" NA NA "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 9: Endometrial stromal cells - Transcription" 36 "unprognostic (1.15e-1)" "unprognostic (4.54e-1)" "unprognostic (8.63e-2)" "unprognostic (5.15e-1)" KRT38 KRTHA8 ENSG00000171360 "Keratin 38" O76015 17 41436154-41440983 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "skin 1: 15.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "head and neck cancer: 1.1;urothelial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 160000000 "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 36: Late spermatids - Unknown function" 57 "unprognostic (1.37e-1)" "unprognostic (4.05e-1)" KRT39 KA35 ENSG00000196859 "Keratin 39" Q6A163 17 40958417-40966948 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 210000 "Cluster 13: Skin - Cornification" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" 28 "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (4.92e-1)" "unprognostic (3.85e-1)" "unprognostic (9.03e-3)" "unprognostic (9.89e-3)" "unprognostic (5.00e-2)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (9.42e-10)" "unprognostic (3.95e-1)" "unprognostic (3.04e-1)" KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19104.8" "Group enriched" "Detected in some" 29 "Squamous epithelial cells: 7437.3;Suprabasal keratinocytes: 21760.6" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cervical cancer: 1151.1;Gallbladder cancer: 1422.0" "Prostate - Urothelial cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 17 "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" KRT40 "FLJ36600, KA36" ENSG00000204889 "Keratin 40" Q6A162 17 40977715-40987135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 2.4;retina: 2.8;skin 1: 2.2" "Cell type enriched" "Detected in some" 4 "Muller glia cells: 27.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.2;Gastric cancer: 4.8" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075961 Supported NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" 288 "HPA075961: " "unprognostic (2.33e-2)" "unprognostic (9.35e-4)" "unprognostic (8.90e-2)" "unprognostic (1.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.92e-1)" "unprognostic (9.09e-3)" "unprognostic (2.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "unprognostic (2.01e-4)" "unprognostic (1.47e-2)" "unprognostic (9.60e-2)" KRT5 "CK-5, EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5700.2;skin 1: 5734.4;vagina: 2086.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 7143.4;Basal squamous epithelial cells: 2581.0;Squamous epithelial cells: 4374.6;Suprabasal keratinocytes: 2568.5" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Region enriched" "Detected in many" 34 "choroid plexus: 129.6" "Immune cell enriched" "Detected in single" 327 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 327 "dendritic cells: 32.6" "Cancer enhanced" "Detected in many" "cervical cancer: 3091.5;Esophageal cancer: 1910.0;head and neck cancer: 3757.4" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB000027, CAB000129, HPA059479, CAB080101" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 15 "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , CAB080101: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 221.9;esophagus: 908.2;skin 1: 276.3;vagina: 222.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 724.1;Serous glandular cells: 442.9;Squamous epithelial cells: 267.1;Suprabasal keratinocytes: 1877.0" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 104.9" "Skin - Outer root sheath cells" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 20 "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 205.8;esophagus: 777.0;vagina: 323.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 934.3;Serous glandular cells: 537.1;Squamous epithelial cells: 295.5;Suprabasal keratinocytes: 2275.1" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 33.2;head and neck cancer: 14.4" "Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 21 "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" KRT7 "CK-7, CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 856.8;thyroid gland: 420.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 8394.3;Alveolar cells type 2: 2030.6;Ductal cells: 2259.6;Extravillous trophoblasts: 4906.6;Mucus glandular cells: 2614.0;Pancreatic endocrine cells: 2519.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 560.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970, CAB080115" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 1300000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Intermediate filaments, Cytosol" "CAB000028: AB_2134589, CAB079970: , CAB080115: , HPA007272: AB_1079181, HPA007315: " "unprognostic (2.71e-3)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (2.74e-1)" "prognostic unfavorable (9.42e-5)" "prognostic unfavorable (7.78e-5)" "unprognostic (4.54e-2)" "prognostic favorable (2.77e-9)" "unprognostic (2.82e-1)" "unprognostic (1.43e-2)" "unprognostic (3.28e-1)" "unprognostic (3.98e-3)" KRT71 "K6IRS1, KRT6IRS, KRT6IRS1" ENSG00000139648 "Keratin 71" Q3SY84 12 52543909-52553145 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 96.9" "Cell type enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA049404 Enhanced NA NA 110000000 "Cluster 82: Skin - Keratinization" "Cluster 65: Non-specific - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 18 "HPA049404: AB_2680748" "unprognostic (9.12e-2)" "unprognostic (2.38e-1)" "unprognostic (1.21e-1)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (3.14e-1)" "unprognostic (1.69e-2)" KRT72 "K6irs, K6IRS2, KRT6, KRT6IRS2" ENSG00000170486 "Keratin 72" Q14CN4 12 52585589-52601538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skin 1: 10.2;testis: 23.0" "Group enriched" "Detected in some" 6 "Early spermatids: 21.6;Late spermatids: 68.0;Spermatocytes: 44.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Leukemia: 2.4" "Lung - NK-cells (Lung), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065523 Enhanced NA NA "Cluster 21: Testis - Unknown function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 16 "HPA065523: AB_2685504" "unprognostic (3.36e-1)" "unprognostic (7.20e-2)" "unprognostic (3.41e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (4.38e-3)" "unprognostic (4.82e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.19e-1)" KRT73 "K6IRS3, KRT6IRS3" ENSG00000186049 "Keratin 73" Q86Y46 12 52607570-52618559 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 16.5" "Cell type enriched" "Detected in some" 4 "NK-cells: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "naive CD4 T-cell: 8.9;naive CD8 T-cell: 3.1" "Lineage enriched" "Detected in single" 13 "T-cells: 8.9" "Cancer enriched" "Detected in single" 10 "Leukemia: 1.7" "Lung - NK-cells (Lung), Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA044031 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 13: Skin - Cornification" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 "HPA044031: AB_10963434" "unprognostic (2.23e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (2.12e-3)" "unprognostic (2.11e-3)" "unprognostic (4.94e-1)" KRT75 K6HF ENSG00000170454 "Keratin 75" O95678 12 52424070-52434371 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 26.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.0;Basal respiratory cells: 1.3;Late spermatids: 3.8;Pancreatic endocrine cells: 5.1;Serous glandular cells: 2.2;Suprabasal keratinocytes: 4.7" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 36.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.4" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019367, HPA076201" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1500000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 103 Cytosol "Plasma membrane" "HPA019367: AB_1852239, HPA076201: AB_2686786" "unprognostic (2.83e-2)" "unprognostic (2.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (8.85e-3)" "unprognostic (2.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (6.60e-2)" "unprognostic (9.20e-2)" "unprognostic (5.19e-2)" "unprognostic (2.45e-1)" "unprognostic (8.98e-2)" "unprognostic (1.94e-1)" KRT76 "HUMCYT2A, KRT2B, KRT2P" ENSG00000185069 "Keratin 76" Q01546 12 52768155-52777345 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "lymphoid tissue: 2.5;salivary gland: 2.5" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 850.5" "Cancer enriched" "Detected in single" 12 "head and neck cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA019656, HPA019696" Approved NA NA 310000000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 33 "HPA019656: AB_1852241, HPA019696: AB_1852243" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 264.6" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 9.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 66.2" "Cell type enhanced" "Detected in some" "granulocytes: 2.0;Late spermatids: 1.4;Melanocytes: 3.4" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 4.7;Sarcoma: 2.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced NA NA 1900000000 "Cluster 13: Skin - Cornification" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 18 "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 212.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 94.1;Ductal cells: 52.9;Glandular and luminal cells: 33.0;Mucus glandular cells: 45.8;Pancreatic endocrine cells: 32.3;Suprabasal keratinocytes: 33.5;Syncytiotrophoblasts: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" KRT81 "Hb-1, KRTHB1" ENSG00000205426 "Keratin 81" Q14533 12 52285913-52291534 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 140.1" "Group enriched" "Detected in some" 5 "Breast glandular cells: 39.7;Pancreatic endocrine cells: 101.9" "Cancer enhanced" "Detected in many" "breast cancer: 46.1;cervical cancer: 49.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 49 "basophil: 171.6" "Lineage enriched" "Detected in many" 49 "granulocytes: 171.6" "Cancer enhanced" "Detected in many" "breast cancer: 443.2" HPA049778 Supported NA NA 130000000 "Cluster 46: Basophils - Proteolysis" "Cluster 82: Skin - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 22 "HPA049778: AB_2680877" "unprognostic (1.69e-2)" "unprognostic (5.61e-2)" "unprognostic (6.57e-2)" "unprognostic (2.90e-1)" "unprognostic (5.64e-2)" "unprognostic (1.77e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-3)" "unprognostic (1.87e-1)" "unprognostic (5.10e-2)" "unprognostic (4.89e-2)" "unprognostic (2.21e-1)" "unprognostic (2.64e-4)" "unprognostic (5.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.25e-1)" "unprognostic (7.31e-2)" KRT82 "Hb-2, KRTHB2" ENSG00000161850 "Keratin 82" Q9NSB4 12 52393931-52406335 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "skin 1: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058715, HPA067230" Enhanced NA NA 29000000 "Cluster 13: Skin - Cornification" "Cluster 70: DU4475 - Unknown function" 11 "HPA058715: AB_2683798, HPA067230: AB_2685807" "unprognostic (3.04e-1)" "unprognostic (3.59e-3)" KRT83 "Hb-3, KRTHB3" ENSG00000170523 "Keratin 83" P78385 12 52314301-52321398 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 64.7" "Cell type enhanced" "Detected in single" "Mucus glandular cells: 1.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.7" HPA049778 Supported NA NA 130000000 "Cluster 82: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 75: Serous glandular cells - Salivary secretion" 31 "HPA049778: AB_2680877" "unprognostic (7.03e-2)" "unprognostic (2.17e-1)" "unprognostic (2.99e-1)" "unprognostic (3.30e-5)" "unprognostic (3.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-2)" "unprognostic (2.43e-1)" "unprognostic (1.12e-3)" "unprognostic (7.49e-3)" "unprognostic (2.16e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" KRT84 "Hb-4, KRTHB4" ENSG00000161849 "Keratin 84" Q9NSB2 12 52377812-52385652 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.4;skin 1: 1.8" "Cell type enriched" "Detected in single" 34 "Suprabasal keratinocytes: 16.1" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 8.8;head and neck cancer: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA039714 Supported NA NA 67000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA039714: AB_2676641" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" KRT85 "Hb-5, KRTHB5" ENSG00000135443 "Keratin 85" P78386 12 52360006-52367481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 167.2" "Group enriched" "Detected in some" 6 "Early spermatids: 5.0;Late spermatids: 15.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049778 Supported NA NA 110000000 "Cluster 82: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 22 "HPA049778: AB_2680877" "unprognostic (1.36e-2)" "unprognostic (3.93e-1)" "unprognostic (7.27e-3)" "unprognostic (5.71e-2)" "unprognostic (2.36e-1)" "unprognostic (4.72e-2)" "unprognostic (9.22e-4)" "unprognostic (1.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.38e-1)" KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 145.7" "Group enriched" "Detected in some" 5 "Early spermatids: 45.8;Late spermatids: 21.7;NK-cells: 38.9;T-cells: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "basophil: 87.8" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.8" "Group enriched" "Detected in many" 5 "breast cancer: 101.1;pancreatic cancer: 27.5" "Pancreas - Ductal cells, Skin - Hair cortex cells, Testis - Early spermatids, Testis - Late spermatids" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 41: Basophils - Unknown function" "Cluster 82: Skin - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 38 Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43996226 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 79: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 6 Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" LY6G5B "C6orf19, G5b" ENSG00000240053 "Lymphocyte antigen 6 family member G5B" Q8NDX9 6 31669976-31673776 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Langerhans cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA048307 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA048307: AB_2680348" "unprognostic (2.69e-2)" "unprognostic (1.52e-1)" "unprognostic (8.53e-2)" "unprognostic (1.44e-2)" "unprognostic (5.80e-2)" "unprognostic (9.85e-3)" "unprognostic (5.04e-3)" "unprognostic (8.34e-3)" "unprognostic (5.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-4)" "unprognostic (7.27e-3)" "unprognostic (1.98e-5)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.00e-2)" "unprognostic (3.98e-4)" LY6G5C "C6orf20, G5c, NG33" ENSG00000204428 "Lymphocyte antigen 6 family member G5C" Q5SRR4 6 31676684-31684040 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enhanced" "Detected in many" "Early spermatids: 28.8;Spermatocytes: 16.9;Spermatogonia: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038690 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 50: Lymphoma - Unknown function" "Cluster 57: Platelets - Hemostasis" "HPA038690: AB_10673286" "unprognostic (1.51e-2)" "unprognostic (7.26e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.07e-4)" "unprognostic (4.83e-1)" "unprognostic (6.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-2)" "unprognostic (5.63e-2)" "unprognostic (3.74e-5)" "unprognostic (5.84e-2)" "unprognostic (3.78e-4)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.88e-2)" "unprognostic (1.39e-2)" LY6G6C "C6orf24, G6c, NG24" ENSG00000204421 "Lymphocyte antigen 6 family member G6C" O95867 6 31718648-31721746 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "skin 1: 495.1" "Cell type enriched" "Detected in many" 6 "Suprabasal keratinocytes: 149.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.6" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 6 "unprognostic (1.21e-1)" "unprognostic (3.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.85e-3)" "unprognostic (2.59e-3)" "unprognostic (1.35e-1)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (4.13e-1)" "unprognostic (1.76e-3)" "unprognostic (2.85e-1)" "unprognostic (8.80e-7)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.09e-2)" "unprognostic (9.38e-2)" LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715348-31717919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "seminal vesicle: 6.5;skin 1: 23.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "colorectal cancer: 46.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 6.1" "Not detected" "Not detected" HPA054412 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.9;Cone photoreceptor cells: 8.5;Excitatory neurons: 11.8;Horizontal cells: 8.8;Inhibitory neurons: 11.7;Sertoli cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 4 Cytosol "Cytokinetic bridge" "HPA003047: AB_1079298" "unprognostic (9.30e-2)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "unprognostic (3.94e-2)" "unprognostic (5.61e-3)" "unprognostic (8.72e-3)" "unprognostic (2.41e-3)" "unprognostic (1.43e-1)" "prognostic favorable (3.95e-4)" "unprognostic (7.91e-2)" "prognostic favorable (6.86e-6)" "unprognostic (4.60e-3)" "unprognostic (2.71e-1)" "unprognostic (6.03e-3)" "unprognostic (5.99e-3)" MED21 "SRB7, SURB7" ENSG00000152944 "Mediator complex subunit 21" Q13503 12 27022546-27066343 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 249.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017177 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" 17 Nucleoplasm "Nucleoli, Cytosol" "HPA017177: AB_1857665" "unprognostic (3.02e-1)" "unprognostic (7.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (7.18e-3)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" "unprognostic (7.32e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.74e-8)" "unprognostic (3.18e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Adipocytes: 217.5;Endothelial cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 84000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" MOCS3 "dJ914P20.3, UBA4" ENSG00000124217 "Molybdenum cofactor synthesis 3" O95396 20 50958818-50963929 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis, tRNA processing" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 95.4;Late spermatids: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027556 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 78: Testis - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 21: Early spermatids - Spermatogenesis" 3 "HPA027556: AB_2672333" "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" "unprognostic (3.16e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (3.76e-1)" "unprognostic (3.19e-1)" "unprognostic (1.33e-2)" "unprognostic (8.67e-3)" "unprognostic (4.90e-2)" "prognostic favorable (7.55e-4)" "unprognostic (8.39e-2)" "unprognostic (8.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" MYO1E "HuncM-IC, MGC104638, MYO1C" ENSG00000157483 "Myosin IE" Q12965 15 59132434-59372871 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 23.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003003, HPA023886" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 13000 "Cluster 13: Non-specific - Mitochondria" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Oligodendrocytes - Unknown function" 2 "Nucleoplasm, Plasma membrane" Cytosol "HPA003003: , HPA023886: AB_1854253" "unprognostic (7.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (5.38e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (2.41e-1)" "unprognostic (7.92e-2)" "unprognostic (7.31e-2)" "unprognostic (9.71e-2)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N-alpha-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929225-153935080 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 41 Cytosol Nucleoli "CAB006269: AB_425759, HPA030711: AB_2673579" "unprognostic (7.57e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (1.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (9.01e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (3.29e-8)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (7.48e-3)" NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 620.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Late spermatids - Spermatogenesis" 9 Mitochondria Nucleoplasm "HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (2.26e-1)" "unprognostic (7.85e-3)" "unprognostic (3.67e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (9.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.57e-7)" "unprognostic (7.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.93e-2)" "prognostic favorable (5.75e-4)" NEIL1 "FLJ22402, FPG1, hFPG1, NEI1" ENSG00000140398 "Nei like DNA glycosylase 1" Q96FI4 15 75346955-75357115 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.3;memory B-cell: 4.9;naive B-cell: 6.7;NK-cell: 16.3" "Group enriched" "Detected in many" 11 "B-cells: 6.7;NK-cells: 16.3;T-cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054084 Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: B-cells - B-cell function" Nucleoplasm "HPA054084: AB_2682372" "unprognostic (9.84e-3)" "unprognostic (1.19e-1)" "unprognostic (1.15e-2)" "unprognostic (4.62e-3)" "unprognostic (3.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.24e-2)" "unprognostic (1.17e-3)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.50e-3)" "unprognostic (8.60e-2)" "unprognostic (9.24e-2)" "unprognostic (2.05e-1)" "unprognostic (3.03e-1)" "unprognostic (2.27e-3)" NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 23.0" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.1;Extravillous trophoblasts: 3.3;Oocytes: 10.3;Plasma cells: 4.4;Squamous epithelial cells: 4.2;Undifferentiated cells: 3.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.4" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 52: Non-specific - Cell proliferation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" "No annotated function" NA NA 4000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Non-specific - DNA binding" "HPA026763: AB_1854379, HPA028488: AB_2672638" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (7.24e-2)" "unprognostic (7.41e-3)" "unprognostic (3.80e-3)" "unprognostic (5.35e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.54e-6)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (4.28e-1)" "unprognostic (2.28e-2)" NUDC ENSG00000090273 "Nuclear distribution C, dynein complex regulator" Q9Y266 1 26900238-26946871 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 750.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027183, HPA028105" Enhanced Enhanced Cytosol NA NA 140000 "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 43: Hepatocytes - Metabolism" 11 Cytosol "HPA027183: AB_10600086, HPA028105: AB_10601988" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.61e-2)" "unprognostic (6.52e-3)" "unprognostic (2.30e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-2)" "unprognostic (3.82e-1)" "unprognostic (3.26e-2)" "unprognostic (2.90e-2)" "unprognostic (1.55e-1)" "unprognostic (2.53e-1)" "unprognostic (5.10e-2)" OAS2 ENSG00000111335 "2'-5'-oligoadenylate synthetase 2" P29728 12 112978395-113011723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 65.5" "Cell type enhanced" "Detected in many" "Adipocytes: 22.4;Hofbauer cells: 24.1;Kupffer cells: 18.8;Macrophages: 23.4;monocytes: 21.0;NK-cells: 18.2;Plasma cells: 18.5;T-cells: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003320, CAB024984" Approved Approved Centrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 58: Macrophages - Innate immune response" 1 Centrosome "CAB024984: , HPA003320: " "unprognostic (2.39e-1)" "unprognostic (9.51e-2)" "unprognostic (2.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.34e-1)" "unprognostic (7.94e-2)" "unprognostic (4.79e-2)" "unprognostic (2.05e-2)" "unprognostic (1.31e-1)" "unprognostic (7.64e-3)" "prognostic unfavorable (4.63e-4)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.94e-2)" PBRM1 "BAF180, PB1, SMARCH1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 3 Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" PDCD6 "ALG-2, PEF1B" ENSG00000249915 "Programmed cell death 6" O75340 5 271621-314974 "Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 95.3;Proximal enterocytes: 77.0;Undifferentiated cells: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047221 Supported Nucleoplasm,Cytosol No No 1800000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 80: Non-specific - Endocytosis" "Cluster 27: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 12 Cytosol Nucleoplasm "HPA047221: " "unprognostic (1.32e-1)" "unprognostic (5.01e-2)" "unprognostic (2.10e-2)" "unprognostic (4.41e-3)" "unprognostic (4.94e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.47e-5)" "unprognostic (1.56e-1)" "unprognostic (1.27e-2)" "unprognostic (4.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (5.16e-6)" "unprognostic (7.97e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-1)" "prognostic favorable (2.19e-4)" PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011905, CAB016212, HPA051110, HPA051604" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Transport NA NA 4100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" 15 Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051110: , HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 5808.0;Hofbauer cells: 4235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 2 Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" PHF14 KIAA0783 ENSG00000106443 "PHD finger protein 14" O94880 7 10973336-11169623 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000538, HPA017376" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 Vesicles "Nucleoplasm, Cytosol" "HPA000538: AB_1079604, HPA017376: AB_2732420" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "unprognostic (3.73e-3)" "unprognostic (7.38e-3)" "unprognostic (8.05e-2)" "unprognostic (3.38e-1)" "unprognostic (4.66e-3)" "unprognostic (1.80e-1)" "unprognostic (5.32e-3)" "unprognostic (6.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" "unprognostic (2.33e-1)" PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2191.5;lymphoid tissue: 2040.9;vagina: 1548.4" "Group enriched" "Detected in many" 6 "Basal respiratory cells: 6262.1;Ionocytes: 3011.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 12 "cerebral cortex: 24.5;pons: 14.5;thalamus: 39.8" "Immune cell enriched" "Detected in some" 1026 "neutrophil: 1774.5" "Lineage enriched" "Detected in single" 4390 "granulocytes: 1774.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 544.0;prostate cancer: 235.4" "Colon - Colon enterocytes" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" "Enzyme inhibitor" NA NA 1400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" PIGA "GPI3, PIG-A" ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 62.9;Langerhans cells: 52.3;monocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" 5 "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697256 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1191.2;Inhibitory neurons: 317.0;Oligodendrocyte precursor cells: 264.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 2 Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" PKP2 ENSG00000057294 "Plakophilin 2" Q99959 12 32790745-32896777 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 191.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 542.9;Extravillous trophoblasts: 202.5;monocytes: 319.4;Salivary duct cells: 178.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 5.6;eosinophil: 6.9;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 164.7" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Region enriched" "Detected in many" 4 "hippocampal formation: 20.2" "Low region specificity" "Detected in all" "HPA014314, CAB037336, HPA056908" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "Cell Junctions" Nucleoplasm "CAB037336: , HPA014314: AB_1855451, HPA056908: AB_2683272" "unprognostic (1.89e-1)" "unprognostic (1.70e-2)" "prognostic favorable (8.55e-4)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.90e-1)" "unprognostic (1.83e-2)" "unprognostic (5.94e-3)" "unprognostic (2.22e-1)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (3.76e-2)" PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 103.9" "Cell type enriched" "Detected in some" 6 "Plasma cells: 15.7" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 3.7;naive B-cell: 3.7;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 3.7;dendritic cells: 2.0" "Group enriched" "Detected in some" 7 "lymphoma: 2.0;Myeloma: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (4.35e-4)" "prognostic favorable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favorable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" POLD2 ENSG00000106628 "DNA polymerase delta 2, accessory subunit" P49005 7 44114631-44124358 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 291.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026745 Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 5 Nucleoplasm "HPA026745: AB_1855520" "unprognostic (9.09e-2)" "unprognostic (1.41e-1)" "unprognostic (9.89e-2)" "unprognostic (1.84e-3)" "unprognostic (1.55e-1)" "unprognostic (2.10e-3)" "unprognostic (1.50e-3)" "unprognostic (4.94e-3)" "unprognostic (8.17e-2)" "unprognostic (1.01e-3)" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.72e-2)" "unprognostic (2.14e-1)" "unprognostic (5.18e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-3)" PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 72: Alveolar cells - Lung function" 2 Nucleoplasm "HPA040905: AB_10794869, HPA041089: AB_10805836" "unprognostic (1.76e-1)" "unprognostic (5.33e-2)" "unprognostic (1.40e-2)" "unprognostic (5.14e-2)" "unprognostic (3.74e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-3)" "unprognostic (9.36e-2)" "unprognostic (1.16e-2)" "unprognostic (4.00e-3)" "unprognostic (3.13e-3)" "unprognostic (4.15e-1)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11355591 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 992 "salivary gland: 6182.2" "Cell type enriched" "Detected in some" 44 "Serous glandular cells: 9574.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 66: Non-specific - Mitochondria" "Cluster 75: Serous glandular cells - Salivary secretion" PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3818 "salivary gland: 11778.1" "Cell type enriched" "Detected in some" 45 "Serous glandular cells: 6235.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA 25000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-2)" "unprognostic (9.21e-2)" "unprognostic (5.51e-3)" "unprognostic (1.97e-4)" "unprognostic (1.51e-1)" PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265914-11269707 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1882 "salivary gland: 13472.2" "Cell type enriched" "Detected in some" 45 "Serous glandular cells: 98229.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 27000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 207 "salivary gland: 3551.4" "Cell type enriched" "Detected in some" 42 "Serous glandular cells: 38773.3" "Group enriched" "Detected in some" 10 "lung cancer: 2.0;melanoma: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (1.05e-1)" "unprognostic (8.25e-2)" PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.4;testis: 53.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.0;Extravillous trophoblasts: 35.1;Oocytes: 73.5;Spermatocytes: 77.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cell proliferation" 5 "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" PRH1 Pa ENSG00000231887 "Proline rich protein HaeIII subfamily 1" 12 10824960-11171608 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 13 "salivary gland: 229.6;testis: 57.4" "Cell type enriched" "Detected in many" 14 "Serous glandular cells: 24501.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Neurons - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (1.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.83e-3)" "unprognostic (3.61e-1)" "unprognostic (1.66e-1)" "unprognostic (3.70e-1)" "unprognostic (6.81e-2)" "unprognostic (6.85e-2)" "unprognostic (7.35e-3)" "unprognostic (2.14e-1)" "unprognostic (5.00e-3)" "unprognostic (1.16e-1)" "unprognostic (1.61e-2)" "unprognostic (1.50e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-2)" "unprognostic (2.68e-1)" PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 909 "salivary gland: 22313.4" "Cell type enriched" "Detected in some" 40 "Serous glandular cells: 24492.9" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 21000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" "unprognostic (3.59e-1)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.01e-2)" "unprognostic (7.37e-2)" "unprognostic (1.63e-5)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.26e-1)" "unprognostic (3.43e-2)" PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 727.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 22000000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 15: Non-specific - Mixed function" 16 "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No 2100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Mixed function" 9 Nucleoplasm "Nuclear bodies, Cytosol" "HPA052408: AB_2681820, HPA054902: AB_2682635" "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308425-161411717 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm NA NA 26000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 18 Nucleoplasm "HPA002114: AB_1855850, HPA003828: AB_2667057" "unprognostic (3.50e-3)" "unprognostic (1.48e-1)" "unprognostic (9.61e-2)" "unprognostic (6.63e-2)" "unprognostic (2.57e-1)" "unprognostic (7.61e-3)" "prognostic unfavorable (2.66e-8)" "unprognostic (3.11e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-3)" "unprognostic (9.84e-3)" "unprognostic (3.02e-1)" "prognostic unfavorable (3.10e-6)" "unprognostic (2.86e-2)" "unprognostic (4.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.66e-1)" PTGES3L-AARSD1 ENSG00000108825 "PTGES3L-AARSD1 readthrough" Q9BTE6 17 42950526-42980528 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 16.9;tongue: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 16 "dendritic cells: 1.5" "Low cancer specificity" "Detected in many" "HPA021408, HPA022869, HPA023714" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Plasma cells - Protein processing" "Nuclear membrane, Cytosol" "HPA021408: AB_1844410, HPA022869: AB_1844411, HPA023714: AB_1844412" "unprognostic (6.47e-2)" "unprognostic (1.25e-1)" "unprognostic (2.87e-1)" "unprognostic (5.44e-2)" "unprognostic (9.34e-4)" "unprognostic (1.56e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-2)" "unprognostic (1.82e-1)" "unprognostic (5.13e-1)" "unprognostic (3.27e-2)" "unprognostic (1.91e-4)" "unprognostic (1.83e-1)" PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.5;endometrium 1: 5.4;intestine: 7.4" "Group enriched" "Detected in some" 7 "Excitatory neurons: 192.5;Inhibitory neurons: 153.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.2;ovarian cancer: 10.4" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 4 "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" RAB3IL1 GRAB ENSG00000167994 "RAB3A interacting protein like 1" Q8TBN0 11 61897301-61920269 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.5;Hofbauer cells: 57.8;Late spermatids: 147.0;Leydig cells: 52.0;Lymphatic endothelial cells: 40.3;Peritubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039723 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Late spermatids - Unknown function" 24 "Centriolar satellite, Cytosol" "HPA039723: AB_10795406" "unprognostic (1.62e-1)" "unprognostic (3.59e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (1.97e-2)" "unprognostic (8.95e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (7.93e-2)" "unprognostic (2.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.42e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.59e-3)" RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic subunit alpha 1" Q6GYQ0 14 35538352-35809304 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 208.0;Inhibitory neurons: 224.1;Oligodendrocyte precursor cells: 224.5;Oligodendrocytes: 384.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved Mitochondria,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol Mitochondria "HPA000851: AB_1078945" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (8.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-2)" "unprognostic (7.65e-2)" "unprognostic (1.17e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-2)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "prognostic favorable (9.76e-5)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 55: Non-specific - Transcription" 6 Nucleoplasm "CAB015201: , HPA019824: AB_1856113, HPA049642: AB_2680839" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (4.91e-2)" "unprognostic (9.67e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.37e-4)" "prognostic favorable (7.97e-4)" "unprognostic (2.88e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" RBM15B "HUMAGCGB, OTT3" ENSG00000259956 "RNA binding motif protein 15B" Q8NDT2 3 51391285-51397908 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036645, HPA058136" Approved Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 33: Non-specific - DNA binding" 1 Nucleoplasm "HPA036645: AB_10671965, HPA058136: AB_2683618" "unprognostic (2.65e-3)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (1.39e-1)" "unprognostic (5.29e-1)" "unprognostic (5.28e-2)" "unprognostic (3.13e-3)" "unprognostic (1.70e-1)" "unprognostic (5.25e-2)" "unprognostic (3.11e-1)" "unprognostic (3.39e-1)" "unprognostic (3.01e-2)" "prognostic favorable (1.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (3.84e-1)" REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 100880.7" "Cell type enriched" "Detected in some" 14 "Exocrine glandular cells: 77260.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 47 "breast cancer: 94.7;colorectal cancer: 64.6;Gastric cancer: 52.0;Rhabdoid: 138.8" "Low region specificity" "Detected in single" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" "No annotated function" NA NA 68000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 38577.5" "Cell type enriched" "Detected in some" 7 "Exocrine glandular cells: 25526.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "HPA045549, HPA045579" Supported "Secreted to digestive system" "No annotated function" NA NA 32000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533853-101563344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA029442, HPA051773" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Retina & Testis - Cilium" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 13 Nucleoplasm "CAB012478: , HPA029442: , HPA051773: AB_2681604" "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" RPS3 "FLJ26283, FLJ27450, MGC87870, S3" ENSG00000149273 "Ribosomal protein S3" P23396 11 75399515-75422280 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" HPA063339 Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA 560000 "Cluster 33: Non-specific - ATP binding" "Cluster 18: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 14 "Endoplasmic reticulum, Cytosol" "HPA063339: AB_2684990" "unprognostic (3.62e-2)" "unprognostic (6.94e-3)" "unprognostic (2.64e-1)" "unprognostic (1.44e-2)" "unprognostic (5.55e-2)" "unprognostic (1.08e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.27e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.92e-6)" "unprognostic (3.22e-1)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (2.19e-1)" RSL24D1 "C15orf15, HRP-L30-iso, L30, RPL24, RPL24L" ENSG00000137876 "Ribosomal L24 domain containing 1" Q9UHA3 15 55180806-55197049 "Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062724, HPA063392" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 3 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA062724: AB_2684850, HPA063392: AB_2685002" "unprognostic (3.40e-2)" "unprognostic (3.00e-1)" "unprognostic (3.83e-1)" "unprognostic (7.28e-2)" "unprognostic (3.80e-2)" "unprognostic (1.07e-3)" "unprognostic (6.71e-3)" "unprognostic (1.15e-1)" "unprognostic (6.56e-3)" "unprognostic (1.34e-1)" "unprognostic (6.19e-3)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (4.44e-1)" "unprognostic (4.54e-2)" "unprognostic (4.95e-1)" "unprognostic (2.41e-1)" RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 45.5" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 13 "HPA036357: AB_10673128" "prognostic unfavorable (9.18e-6)" "unprognostic (5.87e-2)" "unprognostic (2.20e-3)" "unprognostic (2.88e-1)" "unprognostic (3.51e-2)" "unprognostic (3.71e-2)" "unprognostic (7.37e-3)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" "unprognostic (2.51e-2)" "unprognostic (1.72e-2)" "prognostic favorable (8.55e-6)" "unprognostic (1.62e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-1)" "unprognostic (5.76e-2)" RXRB "H-2RIIBP, NR2B2, RCoR-1, RXR-beta, RXRbeta" ENSG00000204231 "Retinoid X receptor beta" P28702 6 33193588-33200665 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002003, HPA071592, HPA075035" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 80: Non-specific - Transcription" 10 Nucleoplasm "Nucleoli, Cytosol" "CAB002003: , HPA071592: , HPA075035: " "unprognostic (3.51e-1)" "unprognostic (8.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.22e-2)" "unprognostic (2.00e-2)" "unprognostic (4.71e-3)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-3)" "unprognostic (8.13e-3)" "unprognostic (9.53e-3)" "unprognostic (8.30e-2)" "unprognostic (1.55e-1)" "unprognostic (6.38e-2)" "unprognostic (8.53e-3)" SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23288689-23433763 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Excitatory neurons: 83.4;Inhibitory neurons: 104.0;Mucus glandular cells: 61.7;Oligodendrocyte precursor cells: 71.7;Oligodendrocytes: 103.4;Skeletal myocytes: 82.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 738.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 53: Non-specific - Glycosylation" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 4 "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 232.8;Late spermatids: 456.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047860, HPA056304, HPA060310" Enhanced Supported "Actin filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" 1 "Actin filaments" "HPA047860: AB_2680187, HPA056304: AB_2683094, HPA060310: AB_2684249" "unprognostic (1.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.94e-2)" "unprognostic (3.18e-2)" "unprognostic (6.34e-2)" "unprognostic (3.41e-2)" "unprognostic (2.02e-3)" "unprognostic (1.80e-2)" "unprognostic (9.67e-2)" "unprognostic (8.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (9.12e-2)" SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 469.3;liver: 761.5;testis: 419.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 239.3;Cholangiocytes: 360.6;Glandular and luminal cells: 330.8;Hepatocytes: 174.8;Late spermatids: 271.4;Peritubular cells: 139.8;Sertoli cells: 356.3" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 27.3;liver cancer: 67.0" "Liver - Hepatocytes, Pancreas - Macrophages, Skin - Fibroblast_2, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" Transport NA NA 2100000000 "Cluster 78: Testis - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" SERPINB9 "CAP3, PI9" ENSG00000170542 "Serpin family B member 9" P50453 6 2887270-2903309 "Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 39.9;placenta: 50.5" "Group enriched" "Detected in many" 5 "Langerhans cells: 1891.6;monocytes: 1175.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 46.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "lymphoma: 60.9;testis cancer: 209.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030067 Uncertain Approved Nucleoplasm,Cytosol NA NA 3400000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Nucleoplasm Cytosol "HPA030067: AB_2673295" "unprognostic (6.82e-3)" "unprognostic (8.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-1)" "unprognostic (4.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" "unprognostic (9.48e-2)" "unprognostic (2.12e-2)" "unprognostic (3.83e-3)" "unprognostic (1.06e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (1.66e-6)" "unprognostic (9.90e-2)" "unprognostic (8.56e-2)" "unprognostic (1.27e-1)" "unprognostic (3.76e-2)" SIRPA "BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2" ENSG00000198053 "Signal regulatory protein alpha" P78324 20 1894167-1940592 "CD markers, Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.3" "Cell type enhanced" "Detected in many" "Astrocytes: 131.0;Excitatory neurons: 84.5;Hofbauer cells: 100.3;Macrophages: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 24.1;eosinophil: 48.7;myeloid DC: 13.9;neutrophil: 50.9" "Group enriched" "Detected in many" 150 "dendritic cells: 13.9;granulocytes: 50.9;monocytes: 24.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 121.9" "Adipose subcutaneous - Macrophages, Testis - Spermatogonia" "CAB002776, CAB015122, HPA054437, HPA058511" Enhanced NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" "CAB002776: , CAB015122: AB_677430, HPA054437: AB_2682488, HPA058511: AB_2683738" "unprognostic (9.78e-2)" "unprognostic (2.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.23e-1)" "unprognostic (5.56e-2)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (4.19e-3)" "unprognostic (3.48e-2)" "unprognostic (2.84e-3)" "unprognostic (3.69e-1)" "unprognostic (3.33e-2)" "unprognostic (2.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.55e-2)" "unprognostic (3.55e-2)" "unprognostic (2.24e-2)" SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 833.4;urinary bladder: 434.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 249.8;Lymphatic endothelial cells: 104.4;Smooth muscle cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765948 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" SPSB2 "GRCC9, SSB-2" ENSG00000111671 "SplA/ryanodine receptor domain and SOCS box containing 2" Q99619 12 6870935-6889358 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 33.5;Distal tubular cells: 36.9;Proximal tubular cells: 44.4" "Cancer enriched" "Detected in all" 5 "testis cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055225 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" 8 "HPA055225: AB_2682746" "unprognostic (1.13e-1)" "unprognostic (3.66e-1)" "unprognostic (1.72e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (3.05e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.42e-1)" "unprognostic (2.13e-2)" "unprognostic (4.83e-2)" "unprognostic (1.35e-2)" "unprognostic (2.77e-1)" "unprognostic (9.05e-2)" "unprognostic (2.39e-2)" SRP68 ENSG00000167881 "Signal recognition particle 68" Q9UHB9 17 76038775-76072517 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 174.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 7 "cerebral cortex: 438.2;medulla oblongata: 644.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023303, HPA055617" Approved Supported Cytosol NA NA 23000 "Cluster 45: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 3 Cytosol "HPA023303: AB_1857477, HPA055617: AB_2682863" "unprognostic (1.25e-1)" "unprognostic (8.97e-2)" "unprognostic (3.47e-2)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.28e-5)" "unprognostic (3.31e-2)" "unprognostic (8.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-2)" "unprognostic (4.42e-2)" "unprognostic (8.73e-2)" "unprognostic (4.75e-2)" "prognostic favorable (2.65e-4)" "unprognostic (4.02e-3)" SRSF11 "NET2, p54, SFRS11" ENSG00000116754 "Serine and arginine rich splicing factor 11" Q05519 1 70205682-70253052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008762 Supported Supported "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 9 "Nuclear speckles" "HPA008762: AB_1856782" "unprognostic (7.82e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (2.85e-1)" "unprognostic (5.32e-3)" "unprognostic (1.30e-3)" "prognostic unfavorable (3.91e-4)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (6.25e-3)" "prognostic unfavorable (6.53e-6)" "unprognostic (7.79e-2)" "unprognostic (1.63e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 39: T-cells - T-cell receptor" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 4 "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: AB_2680020" "unprognostic (4.09e-3)" "unprognostic (1.90e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "prognostic favorable (7.03e-4)" "unprognostic (6.55e-2)" "unprognostic (4.51e-2)" "unprognostic (2.62e-2)" "unprognostic (2.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492670-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 473.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 10 "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 431.6;Alveolar cells type 1: 393.3;Endothelial cells: 371.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Neutrophils, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 120 "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" STX8 CARB ENSG00000170310 "Syntaxin 8" Q9UNK0 17 9250471-9576591 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Late spermatids: 939.3;Oocytes: 958.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001540 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Testis - Spermatid development" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 58 Vesicles Cytosol "HPA001540: AB_1080168" "unprognostic (8.68e-2)" "unprognostic (2.29e-2)" "unprognostic (2.53e-1)" "unprognostic (4.14e-3)" "unprognostic (3.36e-1)" "unprognostic (1.58e-2)" "unprognostic (6.91e-2)" "unprognostic (1.19e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (1.86e-3)" "unprognostic (2.54e-1)" "unprognostic (1.45e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.77e-2)" "unprognostic (1.51e-1)" TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825219-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Astrocytes: 5.9;Excitatory neurons: 13.9;Inhibitory neurons: 13.8;Microglial cells: 4.5;Oligodendrocyte precursor cells: 13.2;Oligodendrocytes: 10.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 4 "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" TAS2R13 "T2R13, TRB3" ENSG00000212128 "Taste 2 receptor member 13" Q9NYV9 12 10907926-10909562 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "unprognostic (2.78e-1)" "unprognostic (3.66e-2)" "unprognostic (1.77e-1)" "unprognostic (5.48e-2)" "unprognostic (1.52e-3)" "unprognostic (6.66e-3)" "unprognostic (4.50e-2)" "unprognostic (8.80e-2)" TAS2R14 "T2R14, TRB1" ENSG00000212127 "Taste 2 receptor member 14" Q9NYV8 12 10937408-11171573 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 5.4;Distal tubular cells: 6.1;Horizontal cells: 6.9;Rod photoreceptor cells: 7.2;Skeletal myocytes: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (4.26e-2)" "unprognostic (1.41e-1)" "unprognostic (6.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.78e-1)" "unprognostic (9.85e-3)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (1.93e-2)" "unprognostic (1.22e-4)" "unprognostic (2.45e-2)" "unprognostic (1.07e-1)" "unprognostic (9.29e-3)" "unprognostic (4.71e-3)" TAS2R20 "T2R20, T2R56, TAS2R49" ENSG00000255837 "Taste 2 receptor member 20" P59543 12 10995961-10998304 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 49: Non-specific - Transcription" "unprognostic (4.62e-2)" "unprognostic (2.96e-1)" "unprognostic (1.12e-3)" "unprognostic (2.16e-4)" "unprognostic (2.92e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.98e-2)" "unprognostic (5.14e-4)" "unprognostic (6.23e-3)" "unprognostic (1.27e-9)" "unprognostic (2.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.28e-2)" "unprognostic (6.44e-3)" TAS2R7 "T2R7, TRB4" ENSG00000121377 "Taste 2 receptor member 7" Q9NYW3 12 10801532-10802627 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAS2R8 "T2R8, TRB5" ENSG00000121314 "Taste 2 receptor member 8" Q9NYW2 12 10806051-10807286 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Neurons - Synaptic function" TAS2R9 "T2R9, TRB6" ENSG00000121381 "Taste 2 receptor member 9" Q9NYW1 12 10809094-10810168 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 73: B-cells - B-cell function" TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 85.2;lung: 20.2;placenta: 27.7" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 110.2" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 3.7" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" Other NA NA 4400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Dendritic cells - Antigen presentation" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965822-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 13 Nucleoplasm "Plasma membrane" "HPA052263: AB_2681777" "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavorable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 230.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 18 Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;stomach 1: 26.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 585.1;Paneth cells: 108.7;Proximal enterocytes: 127.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 16.2" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 1 "Nucleoplasm, Cell Junctions" "Plasma membrane" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" TLR8 "CD288, hTLR8" ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 10.3;lymphoid tissue: 16.3" "Group enriched" "Detected in some" 4 "Kupffer cells: 47.8;Macrophages: 21.5;monocytes: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 73 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 77 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001608 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 40: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 1: Erythroid cells - Oxygen transport" Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" TPD52L2 "D54, hD54, TPD54" ENSG00000101150 "TPD52 like 2" O43399 20 63865228-63891545 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047489 Approved Approved Vesicles,Cytosol NA NA 1100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 15: Non-specific - Mixed function" 3 Vesicles Cytosol "HPA047489: AB_2680067" "unprognostic (1.17e-2)" "unprognostic (2.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.63e-3)" "unprognostic (9.95e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (1.74e-8)" "unprognostic (2.79e-1)" "unprognostic (7.07e-2)" "unprognostic (3.33e-2)" "unprognostic (3.15e-3)" TREML2 "C6orf76, dJ238O23.1, FLJ13693, TLT2" ENSG00000112195 "Triggering receptor expressed on myeloid cells like 2" Q5T2D2 6 41189749-41201149 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.3;lymphoid tissue: 9.3" "Cell type enhanced" "Detected in some" "B-cells: 8.4;Early spermatids: 10.2;Late spermatids: 39.0;monocytes: 9.3;Syncytiotrophoblasts: 16.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 23.3;neutrophil: 33.4" "Group enriched" "Detected in many" 15 "B-cells: 23.3;dendritic cells: 9.3;granulocytes: 33.4" "Cancer enhanced" "Detected in some" "Leukemia: 8.4;Myeloma: 13.3" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Stomach - Neutrophils, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 3400000 "Cluster 20: Non-specific - DNA binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Neutrophils - Degranulation" "unprognostic (3.76e-3)" "unprognostic (2.39e-1)" "unprognostic (9.05e-3)" "unprognostic (1.30e-3)" "unprognostic (3.22e-3)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" "unprognostic (7.46e-2)" "unprognostic (2.51e-1)" "unprognostic (2.40e-3)" "unprognostic (2.46e-1)" "unprognostic (2.02e-2)" "unprognostic (7.45e-2)" "unprognostic (1.54e-2)" "unprognostic (6.23e-2)" "unprognostic (6.71e-2)" TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 181.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: B-cells - B-cell function" 17 Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favorable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favorable (8.20e-5)" "prognostic favorable (4.94e-9)" TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.0" "Cell type enhanced" "Detected in many" "Astrocytes: 9.0;Excitatory neurons: 14.1;Inhibitory neurons: 19.2;Oligodendrocyte precursor cells: 16.0;Oligodendrocytes: 8.8" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 29.3;testis cancer: 68.3" "Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000537 Approved "Cell Junctions,Cytosol" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 9: Endometrial stromal cells - Transcription" 2 "Cell Junctions" Cytosol "HPA000537: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.1;skeletal muscle: 1.5;skin 1: 4.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Plasma cells: 14.2;Proximal enterocytes: 21.8;Schwann cells: 15.1;Skeletal myocytes: 8.8;Suprabasal keratinocytes: 13.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 13 Nucleoli "HPA045161: AB_10960706, HPA073181: AB_2686578" "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 26.7;lymphoid tissue: 65.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.2;Oocytes: 47.8;Plasma cells: 18.1;Undifferentiated cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 52: Non-specific - Cell proliferation" 4 Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 Nucleoplasm "HPA026633: AB_2732431, HPA026697: AB_2732432" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 125.5;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 18 Vesicles "Centrosome, Cytosol" "HPA024705: AB_10601776, HPA024781: AB_10602100" "unprognostic (8.28e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-3)" "unprognostic (3.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.31e-2)" "unprognostic (5.88e-3)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (2.18e-1)" VPS72 "Swc2, TCFL1, YL-1, YL1" ENSG00000163159 "Vacuolar protein sorting 72 homolog" Q15906 1 151176304-151195321 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065709 Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 79: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 5 "Nuclear speckles" "HPA065709: AB_2685540" "unprognostic (2.55e-1)" "unprognostic (3.79e-1)" "unprognostic (3.10e-1)" "unprognostic (4.50e-2)" "unprognostic (2.16e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (4.41e-6)" "unprognostic (4.10e-2)" "unprognostic (2.25e-1)" "unprognostic (1.10e-2)" "unprognostic (9.58e-2)" "unprognostic (1.50e-1)" "unprognostic (7.92e-2)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (4.49e-2)" "unprognostic (1.30e-1)" WDR4 "TRM82, TRMT82, Wuho" ENSG00000160193 "WD repeat domain 4" P57081 21 42843094-42879568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, tRNA processing" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017381 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" 4 Nucleoplasm Cytosol "HPA017381: AB_1858807" "unprognostic (3.47e-2)" "unprognostic (2.15e-2)" "unprognostic (4.32e-2)" "unprognostic (2.13e-2)" "unprognostic (2.95e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (5.48e-7)" "unprognostic (2.85e-3)" "unprognostic (5.37e-2)" "unprognostic (2.27e-2)" "unprognostic (4.25e-1)" "unprognostic (4.78e-2)" "unprognostic (2.65e-2)" "unprognostic (1.74e-3)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.46e-2)" WFDC10A "C20orf146, dJ688G8.3, WAP10" ENSG00000180305 "WAP four-disulfide core domain 10A" Q9H1F0 20 45629739-45631196 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 444 "epididymis: 280.5" "Cell type enhanced" "Detected in some" "Early spermatids: 1.0;Late spermatids: 1.8;Oocytes: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" WFDC11 WAP11 ENSG00000180083 "WAP four-disulfide core domain 11" Q8NEX6 20 45648563-45670270 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "epididymis: 91.7" "Group enriched" "Detected in some" 27 "Early spermatids: 39.2;Late spermatids: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" WFDC13 "C20orf138, dJ601O1.3, WAP13" ENSG00000168634 "WAP four-disulfide core domain 13" Q8IUB5 20 45702038-45708817 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "epididymis: 87.3" "Cell type enhanced" "Detected in some" "Oocytes: 2.2;Rod photoreceptor cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (2.53e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-3)" "unprognostic (7.96e-3)" "unprognostic (2.04e-1)" "unprognostic (1.02e-11)" "unprognostic (1.17e-1)" "unprognostic (1.44e-2)" "unprognostic (2.22e-2)" WFDC3 "dJ447F3.3, WAP14" ENSG00000124116 "WAP four-disulfide core domain 3" Q8IUB2 20 45747944-45791932 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 16.2;testis: 19.4" "Group enriched" "Detected in many" 6 "Early spermatids: 131.9;Late spermatids: 221.8;Spermatocytes: 89.5" "Cancer enhanced" "Detected in many" "lung cancer: 2.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 21: Testis - Unknown function" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Late spermatids - Spermatogenesis" 2 "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (5.75e-2)" "unprognostic (9.30e-4)" "unprognostic (6.63e-3)" "unprognostic (4.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-3)" "unprognostic (1.79e-1)" "unprognostic (1.36e-8)" "unprognostic (8.53e-2)" "unprognostic (2.45e-1)" "unprognostic (5.27e-3)" "unprognostic (3.03e-2)" WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 217.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" WFDC8 "C20orf170, dJ461P17.1, WAP8" ENSG00000158901 "WAP four-disulfide core domain 8" Q8IUA0 20 45551153-45579326 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 523 "epididymis: 400.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042710, HPA071119" Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA042710: AB_2732501, HPA071119: AB_2732172" "unprognostic (5.63e-3)" "unprognostic (1.09e-2)" "unprognostic (2.34e-1)" "unprognostic (9.96e-2)" "unprognostic (1.07e-2)" WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 4.4;Langerhans cells: 2.3;NK-cells: 2.9;Spermatocytes: 4.9;Spermatogonia: 3.5;T-cells: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 32 "T-cells: 5.1" "Cancer enriched" "Detected in single" 26 "ovarian cancer: 10.0" "Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" WRNIP1 "bA420G6.2, CFAP93, FAP93, FLJ22526, WHIP" ENSG00000124535 "WRN helicase interacting protein 1" Q96S55 6 2765393-2786952 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" 5 Nucleoplasm "HPA031752: AB_10603004, HPA031753: AB_2674028" "unprognostic (5.52e-2)" "unprognostic (5.95e-2)" "unprognostic (6.83e-3)" "unprognostic (8.35e-3)" "unprognostic (7.66e-2)" "unprognostic (7.10e-2)" "unprognostic (5.63e-3)" "unprognostic (3.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" WWP2 AIP2 ENSG00000198373 "WW domain containing E3 ubiquitin protein ligase 2" O00308 16 69762328-69941741 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 18: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 74: Neutrophils - Degranulation" 51 "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-3)" "unprognostic (2.86e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.14e-1)" "unprognostic (7.50e-2)" "unprognostic (2.08e-2)" "unprognostic (9.81e-2)" "prognostic favorable (5.87e-11)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 84.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 203.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 203.4" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 74: Neutrophils - Degranulation" 1 "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" YBX2 "Contrin, CSDA3, MSY2" ENSG00000006047 "Y-box binding protein 2" Q9Y2T7 17 7288263-7294639 "Predicted intracellular proteins, Transcription factors" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 77 "testis: 535.8" "Group enriched" "Detected in many" 20 "Early spermatids: 338.5;Late spermatids: 396.6;Spermatocytes: 196.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB012332, HPA053904, HPA056744" Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" "CAB012332: AB_776541, HPA053904: AB_2682302, HPA056744: AB_2683223" "unprognostic (1.76e-2)" "unprognostic (4.62e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (6.50e-5)" "unprognostic (9.80e-4)" "unprognostic (4.68e-2)" "unprognostic (2.23e-1)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-4)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (5.31e-1)" "unprognostic (2.35e-2)" ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 5 Nucleoli Nucleoplasm "HPA035782: AB_10603243, HPA061835: AB_2684621" "unprognostic (4.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "prognostic favorable (2.39e-4)" "unprognostic (7.53e-3)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.70e-2)" "unprognostic (2.96e-1)" "unprognostic (9.75e-2)" "unprognostic (4.17e-3)" ZNF195 ENSG00000005801 "Zinc finger protein 195" O14628 11 3339261-3379222 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA030605 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" Nucleoplasm Cytosol "HPA030605: AB_10602686" "unprognostic (2.30e-2)" "unprognostic (5.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (5.40e-2)" "unprognostic (4.02e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (3.10e-2)" "unprognostic (1.39e-2)" "unprognostic (5.94e-2)" "unprognostic (3.14e-1)" "prognostic unfavorable (4.24e-4)" "prognostic unfavorable (7.89e-5)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.54e-2)" "prognostic favorable (4.79e-7)" ZNF266 HZF1 ENSG00000174652 "Zinc finger protein 266" Q14584 19 9412429-9435573 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026836, HPA054110" Uncertain Supported "Nucleoplasm,Vesicles,Rods & Rings" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Neuronal - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" 8 Vesicles "Nucleoplasm, Rods & Rings" "HPA026836: AB_2672018, HPA054110: AB_2682383" "unprognostic (2.50e-2)" "prognostic favorable (1.41e-4)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (7.60e-2)" "prognostic favorable (3.94e-6)" "unprognostic (1.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (4.59e-2)" "unprognostic (9.00e-3)" "prognostic favorable (3.03e-5)" "unprognostic (2.92e-3)" "prognostic unfavorable (1.82e-4)" "unprognostic (7.76e-2)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" "prognostic favorable (9.15e-5)" ZNF382 "FLJ14686, KS1" ENSG00000161298 "Zinc finger protein 382" Q96SR6 19 36604817-36634114 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.4;retina: 16.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.0;Excitatory neurons: 18.5;Horizontal cells: 30.2;Inhibitory neurons: 15.4;Late spermatids: 29.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049259 Approved Approved "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Nuclear speckles" "HPA049259: AB_2680694" "unprognostic (5.43e-3)" "unprognostic (5.16e-2)" "unprognostic (1.17e-1)" "unprognostic (2.68e-3)" "unprognostic (6.13e-2)" "unprognostic (1.85e-3)" "unprognostic (5.63e-2)" "unprognostic (6.64e-2)" "unprognostic (1.12e-2)" "unprognostic (5.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.07e-3)" "unprognostic (1.76e-5)" "unprognostic (8.71e-2)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" "unprognostic (6.22e-2)" BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 119 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: AB_10599488, HPA031219: AB_10601989" "unprognostic (6.12e-3)" "unprognostic (6.97e-2)" "unprognostic (2.90e-1)" "unprognostic (2.33e-3)" "unprognostic (4.38e-2)" "unprognostic (2.73e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.09e-2)" "unprognostic (2.51e-1)" "unprognostic (6.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.15e-8)" "unprognostic (4.39e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-3)" "unprognostic (5.99e-2)" MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Enhanced Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 7 Mitochondria "HPA021234: AB_1854098, HPA029885: AB_2673233" "unprognostic (6.84e-3)" "unprognostic (1.03e-1)" "unprognostic (8.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.97e-1)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.21e-2)" "unprognostic (1.03e-1)" "unprognostic (8.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Hepatocytes: 14.5;Proximal enterocytes: 43.5;Proximal tubular cells: 17.2;Rod photoreceptor cells: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153, HPA071834" Approved Supported Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 38: Proximal tubular cells - Transmembrane transport" Vesicles "HPA036174: AB_2674988, HPA036175: AB_2674989, HPA038153: AB_2675868, HPA071834: " "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "unprognostic (4.90e-2)" "unprognostic (7.22e-3)" "unprognostic (3.83e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (6.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.29e-2)" "unprognostic (9.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (7.11e-4)" APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 130 "liver: 9320.5" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 820.6" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 29 "NK-cells: 3.2" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;Leukemia: 80.3;liver cancer: 81.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA055877 Supported "Secreted to blood" Apolipoprotein NA NA 43000000000 49000000000 "Cluster 14: Non-specific - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1601.1;salivary gland: 504.2" "Group enriched" "Detected in many" 6 "Alveolar cells type 2: 237.0;Paneth cells: 360.7;Proximal enterocytes: 161.8;Serous glandular cells: 507.9;Undifferentiated cells: 211.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 47.6;stomach cancer: 76.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 26.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" Transport NA NA 5200000 "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Centriolar satellite" "HPA040778: AB_2677132" "unprognostic (3.32e-2)" "unprognostic (2.17e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (7.97e-2)" "unprognostic (1.31e-1)" "unprognostic (4.51e-1)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.08e-9)" "unprognostic (2.26e-1)" "unprognostic (2.92e-4)" "unprognostic (2.00e-3)" "unprognostic (2.22e-1)" HERC5 CEB1 ENSG00000138646 "HECT and RLD domain containing E3 ubiquitin protein ligase 5" Q9UII4 4 88457119-88506163 "Predicted membrane proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 56.2" "Group enriched" "Detected in many" 6 "Early spermatids: 115.8;Oocytes: 176.5;Spermatocytes: 313.2;Spermatogonia: 372.0" "Cancer enriched" "Detected in all" 5 "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA043929 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA043929: AB_10962492" "unprognostic (2.87e-1)" "unprognostic (2.10e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (4.46e-5)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.35e-1)" "unprognostic (2.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.23e-2)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (1.61e-1)" KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9254.3;salivary gland: 5321.3" "Group enriched" "Detected in many" 4 "Exocrine glandular cells: 519.0;Intestinal goblet cells: 1401.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 12.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "cerebral cortex: 9.1" HPA059690 Approved "Secreted to digestive system" Enzyme NA NA 10000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 15: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 406.0;esophagus: 1124.3;skin 1: 1284.7;vagina: 410.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1623.9;Basal respiratory cells: 1126.6;Basal squamous epithelial cells: 8361.0;Squamous epithelial cells: 3482.2" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 522.2;head and neck cancer: 469.4" "Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 100 "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" MTFR1 "CHPPR, FAM54A2, KIAA0009" ENSG00000066855 "Mitochondrial fission regulator 1" Q15390 8 65644734-65771261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 239.7;Late spermatids: 849.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023152, HPA056120" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" 2 Mitochondria Cytosol "HPA023152: AB_1854176, HPA056120: AB_2683043" "prognostic unfavorable (4.06e-4)" "unprognostic (4.58e-2)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (6.56e-3)" "unprognostic (3.93e-2)" "unprognostic (1.66e-1)" "unprognostic (3.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.53e-1)" "unprognostic (5.69e-3)" "unprognostic (5.44e-2)" "unprognostic (6.63e-3)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (8.25e-2)" S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP-8, MRP8, P8, S100-A8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34972.5;esophagus: 23877.2;vagina: 10830.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9603.9;Kupffer cells: 6254.3;Serous glandular cells: 4860.9;Squamous epithelial cells: 10605.6;Suprabasal keratinocytes: 41015.2" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Region enhanced" "Detected in all" "cerebral cortex: 66.1" "Group enriched" "Detected in all" 9 "classical monocyte: 26966.7;neutrophil: 53446.0" "Group enriched" "Detected in all" 9 "granulocytes: 53446.0;monocytes: 26966.7" "Group enriched" "Detected in many" 6 "breast cancer: 333.1;cervical cancer: 581.7;head and neck cancer: 730.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10900000 370000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" SHCBP1L C1orf14 ENSG00000157060 "SHC binding and spindle associated 1 like" Q9BZQ2 1 182899865-182953525 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1114 "testis: 111.3" "Group enriched" "Detected in some" 10 "Early spermatids: 822.7;Spermatocytes: 496.5" "Cancer enhanced" "Detected in single" "cervical cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036124, HPA036125, HPA064821" Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 4: Non-specific - Transcription" "Cluster 31: Spermatocytes - Spermatogenesis" 4 "HPA036124: AB_2674953, HPA036125: AB_10671834, HPA064821: AB_2685360" "unprognostic (1.29e-3)" "unprognostic (1.03e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (6.44e-2)" STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 54 "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favorable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2226.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.3;Breast myoepithelial cells: 14.1;Club cells: 9.2;Early spermatids: 5.6;Late spermatids: 9.4;Prostatic glandular cells: 4.5;Serous glandular cells: 14.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "breast cancer: 13.5;liver cancer: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 36000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 165.7;vagina: 94.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 467.2;Distal enterocytes: 308.6;Squamous epithelial cells: 821.6;Suprabasal keratinocytes: 1501.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 29.9;neutrophil: 8.4" "Lineage enriched" "Detected in many" 14 "granulocytes: 29.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 24000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Endoplasmic reticulum" "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 549.7" "Group enriched" "Detected in some" 10 "Basal keratinocytes: 303.9;Suprabasal keratinocytes: 912.6" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;Esophageal cancer: 1.7;ovarian cancer: 3.3" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 13: Skin - Cornification" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" FAM172A "C5orf21, DKFZP564D172, Toupee" ENSG00000113391 "Family with sequence similarity 172 member A" Q8WUF8 5 93617725-94111699 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 165.3;Excitatory neurons: 251.1;Inhibitory neurons: 285.2;Microglial cells: 217.4;Oligodendrocyte precursor cells: 248.6;Oligodendrocytes: 320.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012299, HPA045505" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 Nucleoplasm Cytosol "HPA012299: AB_1845724, HPA045505: AB_2679354" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (3.10e-2)" "unprognostic (7.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-2)" "unprognostic (1.51e-1)" "unprognostic (1.57e-2)" "unprognostic (2.52e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.38e-1)" "unprognostic (6.56e-2)" "unprognostic (1.72e-2)" "unprognostic (1.03e-2)" GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.5;Late spermatids: 156.0;Proximal enterocytes: 393.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" "Growth factor" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 5 Cytosol Mitochondria "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Monocytes - Innate immune response" 1 Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" NFRKB "DKFZp547B2013, INO80G" ENSG00000170322 "Nuclear factor related to kappaB binding protein" Q6P4R8 11 129863636-129895590 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007082, HPA007128" Approved Enhanced Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Testis - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" 1 Nucleoplasm "HPA007082: AB_1079481, HPA007128: AB_1079482" "unprognostic (1.22e-1)" "unprognostic (3.42e-2)" "unprognostic (2.12e-1)" "unprognostic (9.41e-2)" "unprognostic (6.56e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (6.36e-3)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "unprognostic (5.31e-2)" "unprognostic (9.22e-2)" "unprognostic (4.15e-2)" "unprognostic (6.57e-2)" "unprognostic (7.14e-2)" "unprognostic (3.93e-2)" PPP1R17 "C7orf16, GSBS" ENSG00000106341 "Protein phosphatase 1 regulatory subunit 17" O96001 7 31687215-31708455 "Human disease related genes, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.5;brain: 17.6" "Group enriched" "Detected in some" 5 "Late spermatids: 116.1;monocytes: 139.2" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Group enriched" "Detected in many" 4 "amygdala: 18.6;cerebellum: 40.5;hypothalamus: 18.3;midbrain: 21.3;thalamus: 34.9" "Immune cell enriched" "Detected in some" 4 "non-classical monocyte: 52.2" "Lineage enriched" "Detected in many" 21 "monocytes: 52.2" "Cancer enhanced" "Detected in some" "Bone cancer: 4.9;lung cancer: 9.5" "Testis - Late spermatids" "Region enriched" "Detected in many" 32 "cerebellum: 430.8" "HPA047819, HPA073123" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" "HPA047819: AB_2680166, HPA073123: AB_2732219" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (6.56e-2)" "unprognostic (5.55e-2)" "unprognostic (2.33e-1)" SETD1B "KIAA1076, KMT2G, Set1B" ENSG00000139718 "SET domain containing 1B, histone lysine methyltransferase" Q9UPS6 12 121804009-121832656 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021667, HPA059412" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" Nucleoplasm "HPA021667: AB_1856753, HPA059412: AB_2684006" "unprognostic (1.69e-1)" "unprognostic (2.38e-2)" "unprognostic (6.32e-2)" "unprognostic (3.51e-1)" "unprognostic (2.06e-1)" "unprognostic (2.75e-2)" "unprognostic (5.32e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.75e-1)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" SMARCB1 "BAF47, hSNFS, INI-1, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 251.4;Oocytes: 289.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 24.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: B-cells - B-cell function" 33 Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" SMARCC2 "BAF170, CRACC2, Rsc8" ENSG00000139613 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2" Q8TAQ2 12 56162359-56189567 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004321, HPA021213, HPA061788" Supported Enhanced Nucleoplasm NA NA 11000 "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 5 Nucleoplasm "CAB004321: AB_2286337, HPA021213: AB_1857275, HPA061788: AB_2684608" "unprognostic (7.51e-2)" "unprognostic (1.08e-2)" "unprognostic (9.31e-2)" "unprognostic (4.93e-2)" "unprognostic (1.62e-1)" "unprognostic (1.02e-1)" "unprognostic (1.43e-2)" "unprognostic (1.83e-1)" "unprognostic (1.71e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (2.45e-1)" "unprognostic (6.74e-2)" "unprognostic (8.79e-2)" TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 190.5" "Cell type enhanced" "Detected in many" "Early spermatids: 363.8;Glandular and luminal cells: 273.0;monocytes: 409.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 34000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 39: Non-specific - Transcription" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: AB_1857899, HPA018123: AB_1857900" "unprognostic (9.81e-2)" "unprognostic (5.53e-3)" "unprognostic (4.79e-2)" "unprognostic (1.31e-1)" "unprognostic (4.01e-1)" "unprognostic (6.08e-3)" "unprognostic (1.84e-3)" "unprognostic (4.81e-3)" "unprognostic (8.81e-3)" "unprognostic (6.19e-3)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.60e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 8.0;lung: 10.1" "Group enriched" "Detected in some" 11 "Alveolar cells type 1: 26.4;Mesothelial cells: 51.4" "Group enriched" "Detected in many" 7 "lung cancer: 4.6;ovarian cancer: 3.6;renal cancer: 11.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.3" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 73000 "Cluster 57: Lung - Lung function" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: AB_2686770" "unprognostic (6.16e-2)" "unprognostic (1.69e-3)" "unprognostic (2.40e-3)" "unprognostic (9.04e-3)" "unprognostic (5.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (8.94e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-3)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "unprognostic (2.31e-1)" "unprognostic (9.84e-3)" DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565804-44575051 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 3 Nucleoli "Mitotic chromosome" "CAB037320: , HPA019749: AB_1847579" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.08e-3)" "unprognostic (2.12e-3)" "prognostic unfavorable (1.38e-5)" "unprognostic (5.17e-2)" "unprognostic (2.76e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-2)" "unprognostic (6.01e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (2.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.50e-1)" "unprognostic (4.90e-2)"