Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.7;Basal respiratory cells: 75.6;Ionocytes: 72.9;Proximal tubular cells: 98.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 59.5;Excitatory neurons: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 1 Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" AASDH "ACSF4, LYS2, NRPS998" ENSG00000157426 "Aminoadipate-semialdehyde dehydrogenase" Q4L235 4 56338287-56387508 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036472, HPA036473" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA036472: AB_2675142, HPA036473: AB_10673656" "unprognostic (1.95e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (5.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-2)" "unprognostic (8.75e-2)" "unprognostic (1.29e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-3)" "unprognostic (1.59e-1)" "unprognostic (1.73e-1)" "unprognostic (4.52e-2)" "unprognostic (1.85e-3)" AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;intestine: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.1;Oligodendrocytes: 226.4;Schwann cells: 84.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Approved Uncertain Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Oligodendrocytes - Unknown function" 5 Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 147.1;Hepatocytes: 135.0;Kupffer cells: 149.2;Langerhans cells: 126.1;Macrophages: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 9 "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" ABCA10 EST698739 ENSG00000154263 "ATP binding cassette subfamily A member 10" Q8WWZ4 17 69147214-69244846 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 210.9;Excitatory neurons: 88.8;Fibroblasts: 56.2;Inhibitory neurons: 107.9;Late spermatids: 112.9;Leydig cells: 54.0;Microglial cells: 178.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.4" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" HPA014535 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "HPA014535: AB_1844426" "unprognostic (1.45e-4)" "unprognostic (3.17e-1)" "unprognostic (7.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.52e-2)" "unprognostic (1.17e-2)" "unprognostic (3.78e-2)" "unprognostic (1.40e-1)" "unprognostic (4.51e-3)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (4.91e-1)" "unprognostic (2.70e-4)" "unprognostic (5.23e-3)" "unprognostic (6.98e-2)" "unprognostic (4.37e-2)" "unprognostic (9.86e-3)" ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.6;skin 1: 20.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.2;Basal respiratory cells: 7.0;Ionocytes: 6.3;Suprabasal keratinocytes: 32.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.8" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "cerebral cortex: 1.4;hippocampal formation: 1.6" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" ABCA13 "FLJ33876, FLJ33951" ENSG00000179869 "ATP binding cassette subfamily A member 13" 7 48171458-48647497 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "bone marrow: 44.1" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 34.1;Ciliated cells: 52.9;Club cells: 21.9;Ionocytes: 67.0" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 5.2" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063601 Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "Centrosome, Cytosol" "HPA063601: AB_2685057" "unprognostic (8.97e-2)" "unprognostic (5.82e-2)" "unprognostic (3.18e-1)" "unprognostic (6.48e-2)" "unprognostic (2.65e-2)" "unprognostic (5.59e-2)" "unprognostic (5.19e-2)" "unprognostic (2.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.86e-3)" "unprognostic (6.03e-3)" "unprognostic (3.26e-1)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (3.62e-2)" ABCA2 ABC2 ENSG00000107331 "ATP binding cassette subfamily A member 2" Q9BZC7 9 137007234-137028915 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "brain: 189.4" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 361.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042886 Approved Supported Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Oligodendrocytes - Unknown function" Vesicles "HPA042886: AB_2678213" "unprognostic (1.01e-2)" "unprognostic (9.21e-3)" "unprognostic (9.59e-2)" "unprognostic (6.15e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.13e-2)" "unprognostic (5.61e-3)" "unprognostic (1.76e-1)" "unprognostic (2.93e-2)" "unprognostic (2.74e-2)" "unprognostic (6.78e-3)" "unprognostic (3.14e-3)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (1.36e-1)" ABCA3 "ABC-C, ABC3, EST111653, LBM180" ENSG00000167972 "ATP binding cassette subfamily A member 3" Q99758 16 2275881-2340746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;lung: 88.4" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 220.8;Alveolar cells type 2: 553.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007884 Enhanced NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Alveolar cells - Lung function" "HPA007884: AB_1078077" "unprognostic (2.64e-1)" "unprognostic (2.19e-2)" "unprognostic (6.09e-3)" "unprognostic (2.61e-3)" "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-2)" "unprognostic (1.86e-1)" "unprognostic (6.58e-3)" "unprognostic (3.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-2)" "unprognostic (5.33e-2)" "unprognostic (3.32e-2)" "unprognostic (7.85e-2)" "unprognostic (2.91e-1)" "unprognostic (1.30e-1)" ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 43 "choroid plexus: 93.3;retina: 343.6" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 261.7;Rod photoreceptor cells: 517.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.1" "Region enriched" "Detected in many" 17 "choroid plexus: 313.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 36: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA064420: , HPA078826: " "unprognostic (1.25e-1)" "unprognostic (3.93e-1)" "unprognostic (3.29e-2)" "unprognostic (7.17e-4)" "unprognostic (1.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.45e-4)" "unprognostic (3.77e-2)" "unprognostic (5.25e-1)" "unprognostic (3.70e-1)" "unprognostic (5.18e-2)" "unprognostic (1.17e-9)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.72e-4)" ABCA5 EST90625 ENSG00000154265 "ATP binding cassette subfamily A member 5" Q8WWZ7 17 69244311-69327244 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 207.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022032, HPA062904" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "HPA022032: AB_1844427, HPA062904: AB_2732692" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (1.62e-3)" "unprognostic (7.17e-2)" "unprognostic (8.05e-4)" "unprognostic (3.05e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "prognostic favorable (9.97e-5)" "unprognostic (3.60e-2)" "unprognostic (1.09e-3)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.55e-1)" "unprognostic (8.52e-2)" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 75.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.4;Fibroblasts: 120.4;Hepatocytes: 85.4;Inhibitory neurons: 74.7;Langerhans cells: 57.3;Microglial cells: 89.5;Ovarian stromal cells: 83.2;Schwann cells: 69.6" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;lymphoma: 3.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 28.0" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 128.3;Bipolar cells: 112.4;Cone photoreceptor cells: 115.5;Extravillous trophoblasts: 366.9;Rod photoreceptor cells: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: AB_2677550" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (7.26e-4)" "prognostic favorable (1.12e-4)" "unprognostic (8.88e-2)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (1.51e-3)" "unprognostic (3.68e-2)" "unprognostic (8.99e-3)" "unprognostic (2.08e-2)" "unprognostic (3.66e-1)" "unprognostic (7.88e-2)" "unprognostic (7.85e-2)" ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 233.8;Leydig cells: 512.7;Microglial cells: 154.8;Oligodendrocytes: 378.5;Ovarian stromal cells: 128.9;Schwann cells: 228.2;Sertoli cells: 206.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Rhabdoid: 16.0" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.7;Fibroblasts: 92.9;Inhibitory neurons: 70.3;Leydig cells: 94.8;Microglial cells: 217.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 5: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, p-170, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 98.7;intestine: 68.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 101.1;Microglial cells: 544.8;Proximal enterocytes: 247.2" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.0;liver cancer: 17.4" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001716, HPA002199, HPA074614" Enhanced Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" ABCB10 "EST20237, M-ABC2, MTABC2" ENSG00000135776 "ATP binding cassette subfamily B member 10" Q9NRK6 1 229516582-229558707 "Plasma proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 59.3" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044063, CAB044065, HPA055175" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 1: Erythroid cells - Oxygen transport" "CAB044063: AB_353262, CAB044065: AB_2220666, HPA055175: AB_2682727" "unprognostic (1.00e-1)" "unprognostic (1.29e-2)" "unprognostic (5.56e-3)" "unprognostic (5.64e-2)" "unprognostic (2.04e-1)" "unprognostic (8.06e-3)" "unprognostic (9.38e-2)" "unprognostic (2.05e-1)" "unprognostic (4.15e-2)" "unprognostic (5.61e-2)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (8.32e-2)" "unprognostic (2.58e-1)" "unprognostic (3.83e-1)" "unprognostic (5.29e-2)" "unprognostic (3.37e-2)" ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 78.1" "Group enriched" "Detected in some" 5 "Early spermatids: 45.5;Hepatocytes: 122.9" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 83: Liver - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 119.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 202.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 7 "B-cells: 8.2" "Cancer enhanced" "Detected in some" "skin cancer: 9.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 43: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane" "Focal adhesion sites, Cytosol" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.9;Excitatory neurons: 12.5;Gastric mucus-secreting cells: 4.7;Inhibitory neurons: 10.4;Oligodendrocyte precursor cells: 12.7;Oligodendrocytes: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" Transport NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" ABCB8 "EST328128, M-ABC1, MABC1, MITOSUR" ENSG00000197150 "ATP binding cassette subfamily B member 8" Q9NUT2 7 151028422-151047782 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045187 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Mitochondria Nucleoplasm "HPA045187: AB_10964281" "unprognostic (5.29e-2)" "unprognostic (9.17e-3)" "unprognostic (8.28e-2)" "unprognostic (8.32e-2)" "unprognostic (8.63e-3)" "prognostic favorable (5.91e-4)" "unprognostic (4.76e-2)" "unprognostic (3.75e-1)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "prognostic favorable (3.34e-4)" "unprognostic (2.26e-1)" "prognostic favorable (5.88e-4)" "unprognostic (7.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.64e-2)" "unprognostic (1.23e-1)" ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.8;Inhibitory neurons: 40.0;Plasma cells: 99.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Plasma cells - Immunoglobulins & histones" Vesicles "CAB033052: AB_2273463, HPA035113: AB_2674470, HPA035114: AB_10601329" "unprognostic (1.47e-2)" "unprognostic (6.46e-4)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (6.07e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (6.97e-2)" "unprognostic (1.70e-1)" "unprognostic (3.58e-3)" "unprognostic (2.71e-2)" ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" ABCC10 "EST182763, MRP7, SIMRP7" ENSG00000124574 "ATP binding cassette subfamily C member 10" Q5T3U5 6 43427366-43450427 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041607, HPA045464" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: T-cells - T-cell receptor" "HPA041607: AB_2677579, HPA045464: AB_2679336" "unprognostic (2.41e-1)" "unprognostic (2.76e-1)" "unprognostic (1.85e-2)" "unprognostic (2.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (3.01e-3)" "unprognostic (1.85e-2)" "unprognostic (8.88e-2)" "unprognostic (2.64e-1)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.75e-1)" "unprognostic (3.85e-1)" "unprognostic (1.58e-1)" "unprognostic (2.80e-2)" ABCC12 MRP9 ENSG00000140798 "ATP binding cassette subfamily C member 12" 16 48080882-48156018 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 1.4;skeletal muscle: 1.4;testis: 2.8" "Group enriched" "Detected in some" 4 "Early spermatids: 4.6;Excitatory neurons: 5.0;Late spermatids: 3.2;Spermatocytes: 4.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043100 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA043100: AB_10794922" "unprognostic (1.53e-1)" "unprognostic (6.87e-2)" "unprognostic (2.37e-2)" "unprognostic (4.62e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (2.65e-1)" "unprognostic (7.53e-2)" "unprognostic (4.23e-1)" ABCC2 "CMOAT, cMRP, DJS, MRP2" ENSG00000023839 "ATP binding cassette subfamily C member 2" Q92887 10 99782640-99852594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;liver: 118.0" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 213.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 24.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 63.3;Rhabdoid: 79.2" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071145 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA071145: " "unprognostic (1.49e-3)" "unprognostic (5.92e-2)" "unprognostic (1.59e-1)" "unprognostic (3.67e-1)" "unprognostic (1.93e-2)" "unprognostic (2.33e-1)" "unprognostic (2.51e-1)" "unprognostic (7.15e-3)" "unprognostic (5.68e-2)" "unprognostic (2.01e-1)" "unprognostic (4.30e-1)" "unprognostic (1.40e-3)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.95e-1)" "unprognostic (1.26e-2)" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.3;liver: 49.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Distal enterocytes: 227.9;Exocrine glandular cells: 119.5;Gastric mucus-secreting cells: 229.3;Hepatocytes: 150.5;Late spermatids: 128.5;Paneth cells: 182.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.8" "Cell type enriched" "Detected in many" 4 "Microglial cells: 194.1" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 68.3" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 125.7;Excitatory neurons: 97.9;Inhibitory neurons: 117.9;Rod photoreceptor cells: 121.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 323.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: AB_2678797, HPA052295: AB_2681789" "unprognostic (9.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.83e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (4.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.02e-1)" "unprognostic (5.91e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (1.10e-1)" "unprognostic (9.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-2)" ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.4;liver: 45.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 19.1;Hepatocytes: 46.7;Proximal enterocytes: 23.3;Proximal tubular cells: 45.4" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.2" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476894 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 42.2;pancreas: 19.5;pituitary gland: 33.4" "Cell type enhanced" "Detected in some" "Astrocytes: 18.6;Bipolar cells: 47.0;Endometrial stromal cells: 16.4;Enteroendocrine cells: 16.5;Excitatory neurons: 46.6;Horizontal cells: 18.9;Inhibitory neurons: 37.6;Oligodendrocyte precursor cells: 36.8;Pancreatic endocrine cells: 30.6" "Cancer enriched" "Detected in some" 9 "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "thyroid cancer: 3.4" "Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" No NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" Nucleoli "Golgi apparatus, Cytosol" "CAB011451: , HPA042318: AB_2677947" "unprognostic (4.30e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-2)" "unprognostic (9.48e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.53e-3)" "unprognostic (6.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (2.22e-2)" "unprognostic (1.96e-2)" "unprognostic (6.88e-5)" "unprognostic (2.72e-2)" "unprognostic (1.85e-1)" ABCC9 "CMD1O, SUR2" ENSG00000069431 "ATP binding cassette subfamily C member 9" O60706 12 21797389-21942543 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport Receptor "Atrial fibrillation, Cardiomyopathy, Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 39.3" "Cell type enhanced" "Detected in many" "Astrocytes: 68.4;Cardiomyocytes: 37.0;Fibroblasts: 30.5;Hepatocytes: 83.2;Sertoli cells: 46.2;Skeletal myocytes: 53.7;Smooth muscle cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007279 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoplasm, Cytosol" "HPA007279: AB_1844435" "unprognostic (4.82e-2)" "unprognostic (3.62e-2)" "unprognostic (5.51e-4)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (8.30e-2)" "unprognostic (3.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.47e-2)" "unprognostic (8.72e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-1)" "prognostic unfavorable (1.85e-5)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (3.10e-3)" "unprognostic (8.22e-5)" ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 35.9;Sertoli cells: 29.9;Syncytiotrophoblasts: 26.5" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" ABCD3 "PMP70, PXMP1, ZWS2" ENSG00000117528 "ATP binding cassette subfamily D member 3" P28288 1 94418389-94518666 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032026, HPA032027, CAB032516, CAB075749" Enhanced Enhanced Peroxisomes NA NA 12000 "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Basal prostatic cells - Lipid metabolism" 3 Peroxisomes "CAB032516: AB_2257637, CAB075749: AB_2665755, HPA032026: AB_2674117, HPA032027: AB_10602103" "unprognostic (1.41e-2)" "unprognostic (3.21e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (1.56e-1)" "unprognostic (1.94e-2)" "unprognostic (2.54e-2)" "unprognostic (5.10e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-1)" "unprognostic (9.12e-2)" "prognostic favorable (4.84e-5)" "unprognostic (5.45e-2)" "unprognostic (6.20e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" ABCD4 "EST352188, P70R, PMP69, PXMP1L" ENSG00000119688 "ATP binding cassette subfamily D member 4" O14678 14 74285269-74303055 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003396 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Breast glandular cells - Lactation" 1 "HPA003396: AB_1078078" "unprognostic (3.92e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-3)" "unprognostic (5.86e-2)" "unprognostic (3.69e-1)" "unprognostic (1.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.34e-2)" "unprognostic (3.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.21e-3)" "unprognostic (5.26e-2)" "unprognostic (2.35e-2)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (7.45e-3)" "unprognostic (7.93e-3)" ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 118.8;Syncytiotrophoblasts: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.7;neutrophil: 36.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 85.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 198.2;Distal enterocytes: 98.5;Extravillous trophoblasts: 89.8;Hofbauer cells: 125.1;Microglial cells: 177.1;Proximal enterocytes: 212.5" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" ABCG4 WHITE2 ENSG00000172350 "ATP binding cassette subfamily G member 4" Q9H172 11 119149052-119162653 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 22.3;retina: 50.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.2;Cone photoreceptor cells: 54.4;Rod photoreceptor cells: 45.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.4" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057635 Enhanced NA NA "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 5 "HPA057635: " "unprognostic (3.26e-2)" "unprognostic (4.75e-4)" "unprognostic (6.31e-2)" "unprognostic (1.83e-3)" "unprognostic (3.76e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "unprognostic (9.35e-2)" "unprognostic (1.67e-1)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (8.78e-2)" "unprognostic (2.25e-1)" "unprognostic (4.15e-4)" "unprognostic (2.26e-1)" "unprognostic (6.48e-3)" "unprognostic (2.65e-3)" ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 52 "intestine: 30.6;liver: 61.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 67.5;Oocytes: 10.3;Paneth cells: 16.2;Proximal enterocytes: 33.9" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.0" "Group enriched" "Detected in many" 11 "Early spermatids: 257.3;Late spermatids: 1024.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 42: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 36: Late spermatids - Unknown function" 1 "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 5: Enterocytes - Absorption" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" ABHD13 "bA153I24.2, BEM46L1, C13orf6, FLJ14906" ENSG00000139826 "Abhydrolase domain containing 13" Q7L211 13 108218392-108234243 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032143, HPA032144" Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA032143: AB_2674178, HPA032144: AB_10602304" "unprognostic (2.69e-1)" "unprognostic (2.81e-1)" "unprognostic (1.36e-2)" "unprognostic (2.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.63e-1)" "unprognostic (8.75e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-2)" ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981196 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Supported Vesicles NA NA 420000 "Cluster 11: T-cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Bipolar cells - Visual perception" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" ABHD16A "BAT5, D6S82E, NG26" ENSG00000204427 "Abhydrolase domain containing 16A, phospholipase" O95870 6 31686955-31703356 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058606 Approved NA NA 37000 "Cluster 14: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 46 "HPA058606: AB_2683774" "unprognostic (1.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.26e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (3.14e-1)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (6.17e-3)" "unprognostic (1.97e-3)" "unprognostic (6.02e-2)" "unprognostic (1.30e-2)" "unprognostic (9.35e-2)" "unprognostic (1.81e-1)" "unprognostic (5.11e-3)" "unprognostic (1.60e-3)" ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2, acylglycerol lipase" P08910 15 89087459-89202355 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 133.5" "Cell type enhanced" "Detected in all" "Early spermatids: 289.8;Hepatocytes: 331.2;Late spermatids: 500.4;Oligodendrocyte precursor cells: 395.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 70.0;neutrophil: 52.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Cytosol Nucleoplasm "HPA005999: AB_1078080" "unprognostic (6.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.18e-7)" "unprognostic (4.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.4;Syncytiotrophoblasts: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 53.2;Oligodendrocytes: 82.5;Proximal enterocytes: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bone cancer: 53.5" "Skin - Keratinocyte (other), Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" 4 Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 24: Non-specific - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Vesicles" "HPA051772: AB_2681603" "unprognostic (1.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (1.60e-2)" "prognostic favorable (4.76e-4)" "unprognostic (2.27e-2)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "prognostic favorable (4.64e-4)" "unprognostic (8.24e-2)" "unprognostic (2.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.53e-4)" ACBD5 "DKFZp434A2417, KIAA1996" ENSG00000107897 "Acyl-CoA binding domain containing 5" Q5T8D3 10 27168135-27243046 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Transport" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 155.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011861, HPA012145" Enhanced Enhanced Peroxisomes NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" Peroxisomes "HPA011861: AB_1844493, HPA012145: AB_1844494" "prognostic unfavorable (3.33e-4)" "unprognostic (4.93e-1)" "unprognostic (3.68e-1)" "unprognostic (1.34e-1)" "unprognostic (6.21e-2)" "unprognostic (5.98e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (2.69e-1)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.91e-3)" "unprognostic (1.71e-1)" "unprognostic (3.63e-2)" "unprognostic (3.37e-3)" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 257.7;testis: 99.0" "Group enriched" "Detected in many" 20 "Early spermatids: 373.5;Late spermatids: 1317.0;Proximal enterocytes: 1039.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Fibroblast_1, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" Enzyme NA NA 104000000 170000000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" ACE2 ACEH ENSG00000130234 "Angiotensin converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.1;intestine: 237.9;kidney: 85.2" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 201.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 13.9;renal cancer: 26.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" Receptor NA NA 4530000 400000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" 13 "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 182.8;Oligodendrocyte precursor cells: 149.5;Oligodendrocytes: 311.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.5;skeletal muscle: 157.4;tongue: 46.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.1;Erythroid cells: 33.0;Exocrine glandular cells: 63.2;Horizontal cells: 59.2;Paneth cells: 39.8;Proximal enterocytes: 39.3;Skeletal myocytes: 80.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 990000 "Cluster 79: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 310.2" "Group enriched" "Detected in many" 10 "Adipocytes: 571.8;Endothelial cells: 840.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.8;Brain cancer: 1.7;Leukemia: 1.5;Neuroblastoma: 2.2;skin cancer: 2.2" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.1;placenta: 15.4" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.3;Extravillous trophoblasts: 117.3;Lymphatic endothelial cells: 37.3;Syncytiotrophoblasts: 78.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.8;NK-cell: 1.0" "Group enriched" "Detected in many" 7 "granulocytes: 3.8;NK-cells: 1.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Liver - Plasma proteins" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 167.3;Lymphatic endothelial cells: 152.7;monocytes: 47.5;Smooth muscle cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 106.8" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 3 "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 17.0;Ciliated cells: 12.9;Exocrine glandular cells: 9.5;Fibroblasts: 17.8;Gastric mucus-secreting cells: 8.3;Proximal enterocytes: 20.0" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Thyroid - Fibroblasts" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368302 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3512.4" "Cell type enriched" "Detected in many" 443 "Prostatic glandular cells: 16688.0" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 139.9" "Lineage enhanced" "Detected in many" "granulocytes: 139.9" "Cancer enriched" "Detected in many" 36 "prostate cancer: 250.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" Enzyme NA NA 460000 480000 "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 226 "testis: 125.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1739.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 10: Testis - Spermatid development" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" Cytosol "HPA043421: AB_10794182, HPA051013: AB_2681311" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 137.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.1;Distal enterocytes: 60.8;Proximal enterocytes: 62.6;Proximal tubular cells: 105.7;Syncytiotrophoblasts: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 17 "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" ACSF3 ENSG00000176715 "Acyl-CoA synthetase family member 3" Q4G176 16 89088375-89164121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008322 Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" 4 Mitochondria Nucleoplasm "HPA008322: AB_1845294" "unprognostic (1.94e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (1.56e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (5.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.96e-1)" "prognostic favorable (3.76e-5)" "unprognostic (3.36e-2)" "prognostic favorable (5.97e-6)" "unprognostic (2.33e-1)" "unprognostic (5.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.00e-3)" ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 699.7;liver: 1108.8;skeletal muscle: 705.7" "Cell type enhanced" "Detected in all" "Early spermatids: 246.9;Hepatocytes: 1001.0;Late spermatids: 526.5;monocytes: 519.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 456.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 456.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 4: Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 74: Neutrophils - Degranulation" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 166.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 14: Neurons - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Monocytes - Innate immune response" 3 "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 219.0;granulocytes: 432.5;monocytes: 333.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 16000 "Cluster 28: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374116-112428379 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 218.8;intestine: 418.8;liver: 165.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.0;Glandular and luminal cells: 296.7;Proximal enterocytes: 460.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 97.2;colorectal cancer: 99.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 9 Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.4;brain: 30.7;retina: 44.4" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Basal prostatic cells: 74.0;Bipolar cells: 59.3;Cone photoreceptor cells: 161.4;Early spermatids: 63.0;Excitatory neurons: 68.3;Inhibitory neurons: 106.2;Rod photoreceptor cells: 140.3" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040470 Enhanced NA NA "Cluster 11: T-cells - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623235-20698890 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "breast: 209.4" "Cell type enhanced" "Detected in many" "Early spermatids: 11.6;Late spermatids: 22.9;Peritubular cells: 7.6" "Group enriched" "Detected in many" 8 "liver cancer: 14.7;prostate cancer: 36.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Prostate - Prostate glandular cells" "Not detected" "Not detected" HPA046291 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 73: Breast - Lactation" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" 3 "HPA046291: AB_10960704" "unprognostic (1.08e-2)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.49e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (9.46e-2)" "unprognostic (3.10e-1)" "unprognostic (8.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (8.24e-2)" "unprognostic (3.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487669 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1179 "kidney: 267.2;liver: 351.8" "Group enriched" "Detected in some" 8 "Hepatocytes: 564.8;Proximal tubular cells: 318.8" "Group enriched" "Detected in some" 479 "liver cancer: 22.7;renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA057699 Supported NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA057699: AB_2683506" "unprognostic (1.17e-4)" "prognostic favorable (1.41e-5)" "unprognostic (5.25e-1)" "unprognostic (2.42e-1)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (5.10e-1)" "unprognostic (2.09e-1)" ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 331 "kidney: 399.0;liver: 510.9" "Group enriched" "Detected in some" 9 "Hepatocytes: 837.6;Proximal tubular cells: 400.7" "Group enriched" "Detected in some" 449 "liver cancer: 30.9;renal cancer: 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA057699 Supported NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "HPA057699: AB_2683506" "unprognostic (1.34e-2)" "prognostic favorable (3.31e-4)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (6.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" ACSM4 ENSG00000215009 "Acyl-CoA synthetase medium chain family member 4" P0C7M7 12 7304072-7328719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.5;Excitatory neurons: 1.2;Horizontal cells: 1.3;Inhibitory neurons: 1.0;Spermatogonia: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049895 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Spermatogonia - Spermatogenesis" "HPA049895: AB_2680940" "unprognostic (9.50e-5)" "unprognostic (5.45e-2)" "unprognostic (4.84e-2)" "unprognostic (6.06e-4)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-3)" "unprognostic (3.31e-3)" "unprognostic (3.85e-2)" "unprognostic (8.78e-2)" "unprognostic (3.27e-1)" "unprognostic (3.60e-1)" "unprognostic (2.45e-9)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.73e-1)" ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228929 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1;pancreas: 3.1;skin 1: 1.6;stomach 1: 1.6" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Cone photoreceptor cells: 1.7;Early spermatids: 2.6;Excitatory neurons: 3.7;Gastric mucus-secreting cells: 2.4;Inhibitory neurons: 3.2;Oligodendrocytes: 2.0;Rod photoreceptor cells: 4.7" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" HPA044593 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 66: Photoreceptor cells - Visual perception" "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.71e-4)" ACSS1 "ACAS2L, AceCS2L, dJ568C11.3, MGC33843" ENSG00000154930 "Acyl-CoA synthetase short chain family member 1" Q9NUB1 20 25006230-25058980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 175.2" "Group enriched" "Detected in many" 4 "Astrocytes: 284.9;Cytotrophoblasts: 310.5;Syncytiotrophoblasts: 392.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041014, HPA043228" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA041014: AB_2677251, HPA043228: AB_2678372" "unprognostic (6.87e-2)" "prognostic favorable (9.37e-4)" "unprognostic (5.32e-2)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.03e-2)" "unprognostic (3.20e-3)" "prognostic favorable (8.33e-5)" "unprognostic (2.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.43e-1)" "unprognostic (7.72e-2)" "unprognostic (4.58e-3)" "unprognostic (5.85e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (1.60e-1)" ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.5;Hepatocytes: 108.1;Intestinal goblet cells: 122.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.5;monocytes: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 35: Non-specific - Mitochondria" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 62: Hepatocytes - Metabolism" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 159.2;Bipolar cells: 60.1;Early spermatids: 69.1;Hepatocytes: 50.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 7.1;neutrophil: 2.2" "Lineage enriched" "Detected in single" 71 "granulocytes: 7.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 1 Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736251-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" 3 Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.3;Leydig cells: 34.1;Oligodendrocytes: 51.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 38.9" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.3;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 79.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453890-38493142 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025115, HPA040384" Approved NA No "Cluster 3: Non-specific - Unknown function" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 "CAB025115: , HPA040384: AB_2732484" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 93.3" "Cell type enhanced" "Detected in many" "Adipocytes: 98.8;Distal enterocytes: 137.5;Endothelial cells: 95.6;Extravillous trophoblasts: 44.0;Fibroblasts: 58.0;Lymphatic endothelial cells: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" Receptor NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44584896-44652252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 468.5;lymphoid tissue: 238.9" "Cell type enhanced" "Detected in many" "dendritic cells: 107.6;Extravillous trophoblasts: 152.2;monocytes: 104.5;Oocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 163.0;NK-cell: 90.4;non-classical monocyte: 351.2;plasmacytoid DC: 211.2" "Group enriched" "Detected in all" 4 "dendritic cells: 211.2;monocytes: 351.2;NK-cells: 90.4" "Cancer enhanced" "Detected in all" "Leukemia: 168.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 351.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 690000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 51: Oligodendrocytes - Unknown function" 17 "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" ADAM11 MDC ENSG00000073670 "ADAM metallopeptidase domain 11" O75078 17 44758988-44781846 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 94.8" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Cardiomyocytes: 11.7;Excitatory neurons: 45.5;Horizontal cells: 34.0;Inhibitory neurons: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.6" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074550 Enhanced NA NA 23000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA074550: AB_2732259" "unprognostic (1.79e-1)" "unprognostic (7.78e-2)" "unprognostic (1.73e-3)" "unprognostic (2.59e-3)" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (6.37e-2)" "unprognostic (5.41e-2)" "unprognostic (5.46e-3)" "unprognostic (7.16e-2)" "unprognostic (9.99e-16)" "unprognostic (1.39e-1)" "unprognostic (2.51e-1)" "unprognostic (3.11e-1)" "unprognostic (3.00e-1)" ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388477 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 130.4" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 479.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 4.5" "Lineage enriched" "Detected in single" 45 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 41.1;Kidney cancer: 31.8" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" "Cell adhesion" NA NA 14000000 "Cluster 1: T-cells - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 5 "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 161.8;Endothelial cells: 136.5;Extravillous trophoblasts: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.1" "Group enriched" "Detected in all" 5 "dendritic cells: 64.1;monocytes: 39.1" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 19 Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Supported Cytosol NA NA 300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Placenta - Pregnancy" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 3 Cytosol "HPA010738: AB_1078100, HPA051575: AB_2681539" "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (4.23e-5)" ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 45.2;Cone photoreceptor cells: 51.0;dendritic cells: 63.5;Extravillous trophoblasts: 95.8;Langerhans cells: 52.2;Plasma cells: 56.4;Rod photoreceptor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.7;eosinophil: 140.1;memory B-cell: 51.0;naive B-cell: 53.7;neutrophil: 70.8;plasmacytoid DC: 66.9" "Group enriched" "Detected in many" 5 "B-cells: 53.7;dendritic cells: 66.9;granulocytes: 140.1" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 17000 "Cluster 41: Basophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 77: Plasma cells - Protein processing" 3 Vesicles "HPA055537: AB_2797253" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.64e-2)" "unprognostic (1.81e-3)" "unprognostic (2.63e-1)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.90e-12)" "unprognostic (1.44e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" ADAM2 "CT15, FTNB, PH-30b, PH30" ENSG00000104755 "ADAM metallopeptidase domain 2" Q99965 8 39743735-39838227 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 371 "testis: 37.0" "Group enriched" "Detected in some" 4 "Early spermatids: 36.7;Spermatocytes: 75.0" "Cancer enriched" "Detected in single" 5 "prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022390, HPA024621, HPA026581" Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "CAB022390: , HPA024621: AB_1844576, HPA026581: AB_1844577" "unprognostic (4.74e-2)" "unprognostic (1.67e-3)" "unprognostic (3.82e-1)" ADAM20 ENSG00000134007 "ADAM metallopeptidase domain 20" O43506 14 70522358-70535015 "Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 5.1" "Cell type enhanced" "Detected in some" "Astrocytes: 28.5;Early spermatids: 65.4;Excitatory neurons: 43.9;Inhibitory neurons: 35.8;Oligodendrocyte precursor cells: 21.7;Oligodendrocytes: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA059377 Enhanced NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 21: Early spermatids - Spermatogenesis" "HPA059377: AB_2683997" "unprognostic (4.13e-3)" "unprognostic (3.45e-2)" "unprognostic (1.14e-1)" "unprognostic (8.34e-2)" "unprognostic (2.06e-1)" "unprognostic (1.57e-2)" "unprognostic (5.61e-2)" "unprognostic (2.89e-2)" "unprognostic (1.58e-3)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.46e-3)" "unprognostic (2.64e-1)" "unprognostic (6.83e-2)" "unprognostic (5.06e-2)" "unprognostic (9.52e-3)" ADAM21 ADAM31 ENSG00000139985 "ADAM metallopeptidase domain 21" Q9UKJ8 14 70417107-70460427 "Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.4" "Group enriched" "Detected in some" 52 "Early spermatids: 67.4;Late spermatids: 141.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059016 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" 2 "HPA059016: AB_2683882" "unprognostic (7.85e-2)" "unprognostic (7.67e-3)" "unprognostic (4.20e-2)" "unprognostic (1.35e-2)" "unprognostic (5.12e-1)" "unprognostic (1.48e-1)" "unprognostic (5.98e-2)" "unprognostic (2.16e-1)" "unprognostic (3.30e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (6.78e-2)" "unprognostic (1.82e-2)" "unprognostic (1.52e-1)" "unprognostic (2.08e-1)" "unprognostic (2.72e-1)" ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 277.1;Inhibitory neurons: 292.2;Oligodendrocyte precursor cells: 172.6;Oligodendrocytes: 116.9" "Cancer enhanced" "Detected in many" "glioma: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 29.5" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" NA NA 180000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 2 "Cell Junctions" "CAB079064: , HPA050325: AB_2681087" "unprognostic (1.20e-2)" "unprognostic (8.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.89e-2)" "unprognostic (3.09e-1)" "unprognostic (7.84e-3)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-1)" "unprognostic (3.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-4)" "unprognostic (4.70e-2)" ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;parathyroid gland: 80.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 81.1;Excitatory neurons: 396.2;Inhibitory neurons: 227.1;Late spermatids: 59.9;Oligodendrocyte precursor cells: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "Myeloma: 47.8" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" "Cell adhesion" NA NA 890000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 347.9;stomach 1: 107.1" "Cell type enhanced" "Detected in many" "B-cells: 223.9;Gastric mucus-secreting cells: 131.5;Ionocytes: 76.2;Microglial cells: 222.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 72.0;naive B-cell: 87.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" Enzyme NA NA "Cluster 32: Basophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 73: B-cells - B-cell function" 1 "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" ADAM30 svph4 ENSG00000134249 "ADAM metallopeptidase domain 30" Q9UKF2 1 119893533-119896515 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 252 "testis: 25.2" "Group enriched" "Detected in some" 8 "Early spermatids: 105.0;Spermatocytes: 47.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026080 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "HPA026080: AB_1844581" ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 26.6" "Cell type enhanced" "Detected in many" "Early spermatids: 238.7;Excitatory neurons: 36.1;Inhibitory neurons: 28.6;Late spermatids: 55.9;Spermatocytes: 80.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044156, HPA062151" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 Vesicles Nucleoplasm "HPA044156: AB_10796798, HPA062151: AB_2684699" "unprognostic (2.13e-1)" "unprognostic (6.92e-2)" "unprognostic (4.63e-3)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.52e-2)" "unprognostic (5.66e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-1)" "unprognostic (3.38e-2)" "unprognostic (1.13e-7)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (8.34e-3)" "unprognostic (7.82e-2)" ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 72.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.3;Fibroblasts: 39.2;Leydig cells: 21.9;Mesothelial cells: 14.6;Microglial cells: 17.9;Smooth muscle cells: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 12.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" ADAM7 "EAPI, GP-83" ENSG00000069206 "ADAM metallopeptidase domain 7" Q9H2U9 8 24440930-24526970 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 239 "epididymis: 3638.5" "Cell type enriched" "Detected in some" 11 "Early spermatids: 128.4" "Group enriched" "Detected in some" 16 "prostate cancer: 1.0;renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "prostate cancer: 2.5" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008879 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "HPA008879: AB_10601789" "unprognostic (1.03e-3)" "unprognostic (3.96e-4)" ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.8;lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 105.8;Langerhans cells: 163.3;NK-cells: 68.3;T-cells: 36.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 44.4" "Group enriched" "Detected in many" 5 "basophil: 107.8;eosinophil: 259.4;neutrophil: 139.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 53.8" "Adipose visceral - Neutrophils, Breast - T-cells, Heart muscle - Neutrophils, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Langerhans cells - Innate immune response" 4 "HPA064637: AB_2685306" "unprognostic (8.24e-2)" "unprognostic (6.07e-3)" "unprognostic (1.27e-3)" "unprognostic (5.18e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-3)" "unprognostic (3.37e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (3.99e-10)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.32e-2)" ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" Enzyme NA NA 740000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 113.0;ovary: 92.8" "Cell type enhanced" "Detected in many" "Adipocytes: 76.5;Endothelial cells: 119.2;Fibroblasts: 76.3;Lymphatic endothelial cells: 41.4;Oligodendrocytes: 52.1;Smooth muscle cells: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.4" "Cancer enhanced" "Detected in some" "Bone cancer: 8.1;skin cancer: 5.6" "Breast - Endothelial cells, Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" Enzyme NA NA 11000 "Cluster 30: Non-specific - DNA binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" ADCK2 MGC20727 ENSG00000133597 "AarF domain containing kinase 2" Q7Z695 7 140672945-140696261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036036 Approved Uncertain Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" "Centrosome, Cytosol" "HPA036036: AB_10672078" "unprognostic (2.76e-1)" "unprognostic (1.79e-1)" "unprognostic (5.72e-2)" "unprognostic (5.30e-2)" "unprognostic (4.03e-3)" "unprognostic (1.52e-1)" "unprognostic (3.05e-2)" "unprognostic (7.48e-2)" "unprognostic (2.61e-1)" "unprognostic (7.10e-3)" "unprognostic (6.81e-3)" "unprognostic (9.36e-3)" "prognostic favorable (9.75e-5)" "unprognostic (1.89e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (2.13e-1)" ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.8;liver: 18.7;retina: 51.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 263.4;Excitatory neurons: 142.3;Horizontal cells: 98.8;Inhibitory neurons: 113.4;Rod photoreceptor cells: 205.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Uncertain Mitochondria NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" ADCY10 "HCA2, RP1-313L4.2, SAC, SACI, Sacy" ENSG00000143199 "Adenylate cyclase 10" Q96PN6 1 167809386-167914215 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "liver: 5.9;testis: 17.1" "Group enriched" "Detected in some" 8 "Early spermatids: 90.7;Late spermatids: 87.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015243, HPA017749" Approved NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 11: Late spermatids - Unknown function" "HPA015243: AB_1856540, HPA017749: AB_1856541" "unprognostic (1.20e-1)" "unprognostic (2.53e-1)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.05e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.56e-1)" "unprognostic (1.63e-1)" "unprognostic (3.65e-1)" "unprognostic (4.43e-2)" "unprognostic (7.83e-5)" "unprognostic (5.86e-7)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "unprognostic (7.83e-2)" "unprognostic (2.59e-1)" ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396138-7830081 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 36.6;skeletal muscle: 66.0;tongue: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 613.7;Excitatory neurons: 392.3;Inhibitory neurons: 405.6;Oligodendrocyte precursor cells: 170.3;Skeletal myocytes: 109.3" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.0;testis cancer: 3.5" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 34: Neurons - Neuronal signaling" "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 41.5;Leydig cells: 60.4;Sertoli cells: 46.2;Smooth muscle cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Smooth muscle cells - Signal transduction" "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 82.3;Endothelial cells: 73.9;Lymphatic endothelial cells: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005070, HPA048344" Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.0;heart muscle: 102.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.9;Horizontal cells: 37.8;Inhibitory neurons: 42.1;Oligodendrocytes: 83.5;Oocytes: 45.6;Paneth cells: 54.4;Peritubular cells: 70.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in all" 5 "basal ganglia: 388.1" "Region enriched" "Detected in all" 6 "basal ganglia: 206.2" "HPA017730, HPA077682" Uncertain Approved Vesicles NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 42.0;Kupffer cells: 60.4;Langerhans cells: 55.6;Macrophages: 46.7;Microglial cells: 50.1;monocytes: 50.3;NK-cells: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved "Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.1;epididymis: 22.3" "Group enriched" "Detected in some" 5 "Astrocytes: 144.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 130.2" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.2;Rhabdoid: 1.1" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116442 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 51.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 92.1;Inhibitory neurons: 69.6;Oocytes: 287.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 44: Oocytes - Unknown function" "Plasma membrane" Cytosol "HPA041328: AB_2677414, HPA044225: AB_2678863" "unprognostic (1.78e-1)" "unprognostic (5.54e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.61e-2)" "unprognostic (6.93e-2)" "unprognostic (4.76e-3)" "unprognostic (5.40e-2)" "unprognostic (1.37e-1)" "prognostic favorable (5.24e-8)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-2)" ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111474 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.0;fallopian tube: 29.2" "Group enriched" "Detected in some" 4 "Astrocytes: 54.2;Inhibitory neurons: 43.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 36.1" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133087924-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 24.4;Horizontal cells: 23.9;Inhibitory neurons: 23.6;Oligodendrocyte precursor cells: 27.4" "Cancer enriched" "Detected in single" 13 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.5" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA042773: AB_10794764" "unprognostic (8.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (1.09e-2)" "unprognostic (7.51e-3)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.66e-1)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.4;Endometrial stromal cells: 45.0;Fibroblasts: 39.6;Leydig cells: 52.3;Lymphatic endothelial cells: 58.2;Muller glia cells: 26.3;Peritubular cells: 40.6;Smooth muscle cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 29.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 62: Connective tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.2;Hepatocytes: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 280000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 77.5" "Cell type enhanced" "Detected in many" "Astrocytes: 19.8;Bipolar cells: 12.8;Excitatory neurons: 53.9;Horizontal cells: 27.7;Inhibitory neurons: 13.2;Oligodendrocyte precursor cells: 19.3" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.1;Cardiomyocytes: 34.0;Endometrial stromal cells: 45.9;Fibroblasts: 31.6;Mesothelial cells: 75.6;Microglial cells: 24.2;Sertoli cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA 1400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.7;lymphoid tissue: 14.4" "Group enriched" "Detected in some" 5 "Kupffer cells: 32.4;monocytes: 87.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 166.6;eosinophil: 325.5" "Group enriched" "Detected in many" 18 "granulocytes: 325.5;monocytes: 105.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 13.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 29: Monocytes - Innate immune response" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.8" "Cell type enhanced" "Detected in many" "granulocytes: 72.9;Kupffer cells: 72.1;Macrophages: 72.3;monocytes: 238.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.2;eosinophil: 74.8;intermediate monocyte: 46.9;neutrophil: 55.8;non-classical monocyte: 90.2" "Group enriched" "Detected in many" 9 "granulocytes: 74.8;monocytes: 90.2" "Cancer enhanced" "Detected in many" "Leukemia: 7.7" "Lung - Neutrophil_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 18 Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in some" "Macrophages: 7.7;Microglial cells: 3.6;monocytes: 21.0;Mucus glandular cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in many" 7 "basophil: 282.8;eosinophil: 510.3;neutrophil: 491.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 510.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Adipose visceral - Neutrophils, Stomach - Neutrophils" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 209.5" "Cell type enhanced" "Detected in many" "dendritic cells: 152.0;monocytes: 445.8;NK-cells: 300.7;T-cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" Receptor NA Yes 10000000 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 19.7;urinary bladder: 41.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.2;Ciliated cells: 66.8;Club cells: 124.5;Collecting duct cells: 101.1;Glandular and luminal cells: 55.9;Ionocytes: 157.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.8;Early spermatids: 6.1;Late spermatids: 29.8;Microglial cells: 5.4;Oligodendrocytes: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.8;skin 1: 37.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Distal enterocytes: 8.3;Extravillous trophoblasts: 17.3;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 32.1;Syncytiotrophoblasts: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.0" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 209.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Melanocytes: 140.9;NK-cells: 180.6;Syncytiotrophoblasts: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1198.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 10.6;Mucus glandular cells: 11.4;Oligodendrocyte precursor cells: 9.4;Prostatic glandular cells: 14.5;Secretory cells: 21.7;Serous glandular cells: 29.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 145.6" "Cell type enriched" "Detected in some" 5 "Lymphatic endothelial cells: 41.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebral cortex: 22.7" "Immune cell enhanced" "Detected in some" "eosinophil: 142.5;neutrophil: 170.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 170.3" "Group enriched" "Detected in some" 9 "Leukemia: 2.4;lymphoma: 3.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 9 "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" ADGRG4 "GPR112, PGR17, RP1-299I16" ENSG00000156920 "Adhesion G protein-coupled receptor G4" Q8IZF6 X 136300963-136416890 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;intestine: 2.4;retina: 1.1" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 61.8;Paneth cells: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035324 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA035324: AB_10671512" "unprognostic (3.40e-3)" "unprognostic (7.68e-5)" "unprognostic (7.61e-2)" ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.8;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in some" "B-cells: 6.2;dendritic cells: 30.0;Microglial cells: 10.7;NK-cells: 27.1;Plasma cells: 16.9;T-cells: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 126.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 11.0;lymphoma: 6.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 69.7;placenta: 45.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.5;Suprabasal keratinocytes: 40.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017346 Approved NA NA 110000000 "Cluster 11: Liver - Plasma proteins" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 41.7;liver: 24.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 22.4;Intestinal goblet cells: 9.5;Paneth cells: 20.1;Proximal enterocytes: 34.0" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.8;Brain cancer: 1.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056451 Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 3 "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" ADGRL1 "CIRL1, KIAA0821, LEC2, LPHN1" ENSG00000072071 "Adhesion G protein-coupled receptor L1" O94910 19 14147743-14206187 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Excitatory neurons: 51.0;Horizontal cells: 54.1;Inhibitory neurons: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037974 Uncertain NA NA 180000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "HPA037974: AB_10675623" "unprognostic (5.52e-2)" "unprognostic (3.89e-1)" "unprognostic (1.04e-1)" "unprognostic (5.52e-3)" "unprognostic (6.29e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" "unprognostic (5.39e-2)" "unprognostic (2.73e-1)" "unprognostic (5.68e-2)" "prognostic favorable (1.14e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.45e-4)" "unprognostic (7.65e-3)" "unprognostic (1.32e-1)" "unprognostic (3.06e-2)" "unprognostic (2.18e-1)" ADGRL2 "CIRL2, KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81993932 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 873.5;Inhibitory neurons: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61200326-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1" "Group enriched" "Detected in many" 11 "Astrocytes: 553.9;Excitatory neurons: 672.7;Inhibitory neurons: 706.4;Oligodendrocyte precursor cells: 1220.7;Oligodendrocytes: 551.2" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.8" "Group enriched" "Detected in many" 6 "Adipocytes: 559.4;Endothelial cells: 298.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 12.2;thyroid cancer: 15.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "adrenal gland: 516.2" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2093.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 26.4" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 1 "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" ADIG "MGC39724, RP5-1100H13.2, SMAF1" ENSG00000182035 Adipogenin Q0VDE8 20 38581195-38588463 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "testis: 52.0" "Cell type enriched" "Detected in some" 7 "Late spermatids: 1730.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041124 Uncertain NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 63: Late spermatids - Spermatogenesis" "HPA041124: AB_10795534" "unprognostic (2.97e-2)" "unprognostic (7.69e-3)" "unprognostic (2.27e-1)" "unprognostic (4.52e-3)" "unprognostic (1.34e-2)" ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 298.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA043737: AB_10964205" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (5.33e-2)" "unprognostic (7.66e-3)" "unprognostic (4.86e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-3)" "unprognostic (2.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (5.85e-2)" ADNP "ADNP1, KIAA0784" ENSG00000101126 "Activity dependent neuroprotector homeobox" Q9H2P0 20 50888916-50931437 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006371 Supported Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 55: Non-specific - Transcription" 3 Nucleoplasm "HPA006371: AB_1078105" "unprognostic (3.40e-2)" "unprognostic (6.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (6.68e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (1.73e-1)" "unprognostic (1.80e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (3.63e-1)" "unprognostic (1.90e-2)" "unprognostic (1.08e-1)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2;testis: 20.9" "Cell type enhanced" "Detected in some" "Ductal cells: 12.9;Excitatory neurons: 17.5;Muller glia cells: 40.9;Oligodendrocyte precursor cells: 33.0;Oligodendrocytes: 29.3" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" 5 "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 40.1;brain: 111.0;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Gastric mucus-secreting cells: 1.8;Plasma cells: 9.1;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "basal ganglia: 200.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 45.6;Myeloma: 39.1" "Kidney - Endothelial cells" "Region enriched" "Detected in many" 9 "basal ganglia: 399.9" "Region enriched" "Detected in many" 50 "basal ganglia: 187.1" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" 8 "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15945130-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 16.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.2;Basal respiratory cells: 69.1;Basal squamous epithelial cells: 31.2;Langerhans cells: 31.5;Suprabasal keratinocytes: 36.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.3;myeloid DC: 10.5" "Group enriched" "Detected in many" 113 "dendritic cells: 10.5;granulocytes: 17.3;monocytes: 5.9" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820, HPA069342" Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA023265: AB_1845590, HPA023820: AB_1845591, HPA069342: " "unprognostic (7.58e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.42e-1)" "prognostic favorable (2.38e-5)" "unprognostic (2.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.43e-1)" "unprognostic (6.26e-3)" "unprognostic (2.97e-1)" "unprognostic (6.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (4.77e-2)" "unprognostic (5.97e-2)" ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 21.0;liver: 58.3" "Cell type enhanced" "Detected in some" "Astrocytes: 100.0;Early spermatids: 34.5;Inhibitory neurons: 117.6;Late spermatids: 38.2;Oligodendrocyte precursor cells: 107.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 4.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 3 Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.9;liver: 11.2;lymphoid tissue: 11.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 40.1;Hepatocytes: 13.5;Horizontal cells: 8.2;Inhibitory neurons: 31.2;Mesothelial cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.8;cervix: 7.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.0;Inhibitory neurons: 2.3;Sertoli cells: 8.2;Smooth muscle cells: 6.8" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 27.8" "Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" 7 "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 6.7;Ionocytes: 12.9;Langerhans cells: 12.0;Sertoli cells: 8.2;Smooth muscle cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Endothelial cells" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in many" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" ADRA2C "ADRA2L2, ADRA2RL2, ADRARL2" ENSG00000184160 "Adrenoceptor alpha 2C" P18825 4 3766348-3768526 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 82.1;endometrium 1: 55.7" "Cell type enhanced" "Detected in many" "Adipocytes: 24.5;Endometrial stromal cells: 133.1;Fibroblasts: 15.7;Secretory cells: 33.6;Smooth muscle cells: 26.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 18.1" "Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" HPA057688 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 9: Endometrial stromal cells - Transcription" 10 "HPA057688: AB_2683503" "unprognostic (1.44e-2)" "unprognostic (2.21e-3)" "unprognostic (1.23e-1)" "unprognostic (2.02e-2)" "unprognostic (4.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.12e-2)" "unprognostic (6.69e-2)" "unprognostic (1.88e-1)" "unprognostic (3.71e-1)" "unprognostic (3.24e-2)" "unprognostic (9.08e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (6.48e-2)" ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 22.9;lung: 12.7;placenta: 28.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 24.6;Cardiomyocytes: 74.7;Cytotrophoblasts: 79.8;Sertoli cells: 24.5;Syncytiotrophoblasts: 34.7" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 7.9" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 "HPA067972: AB_2685936" "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 191.0;Basal keratinocytes: 282.8;Basal respiratory cells: 137.6;Basal squamous epithelial cells: 174.8;granulocytes: 187.1;Squamous epithelial cells: 272.6;Suprabasal keratinocytes: 166.8" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 50.9" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075322 Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 18 Cytosol "HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 3.9;ovary: 11.3;urinary bladder: 4.5" "Cell type enriched" "Detected in some" 8 "Ovarian stromal cells: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 169 "Bone cancer: 17.7" "Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 100.6;intestine: 95.7;parathyroid gland: 89.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.6;Distal tubular cells: 76.8;Early spermatids: 132.7;Late spermatids: 185.1;Paneth cells: 58.0;Proximal enterocytes: 128.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 10 "choroid plexus: 79.3" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 2 Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" AGER "RAGE, SCARJ1, sRAGE" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 704.7" "Cell type enriched" "Detected in many" 21 "Alveolar cells type 1: 2481.0" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.2" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" Other NA NA 5360000 100000 "Cluster 57: Lung - Lung function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 12 "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" AGL GDE ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850361-99924023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 248.4;tongue: 203.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 147.9;Muller glia cells: 138.3;Skeletal myocytes: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 6 "Gallbladder cancer: 80.4" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 450000 "Cluster 15: NK-cells - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Skeletal myocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: AB_2682455" "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favorable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 118.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 74.4;Oligodendrocyte precursor cells: 31.6;Oligodendrocytes: 35.8;Oocytes: 103.7;Proximal enterocytes: 25.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" AGPAT1 "LPAAT-alpha, LPLAT1" ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 99.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "hypothalamus: 65.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 1 "Endoplasmic reticulum" "Rods & Rings" "HPA048478: AB_2680411, HPA073355: AB_2686596" "prognostic unfavorable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" AGPAT2 "BSCL, LPAAT-beta, LPLAT2" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 357.5;liver: 434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 717.6;Late spermatids: 400.5;Paneth cells: 447.9;Proximal enterocytes: 1298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA019544 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" AGPAT4 "dJ473J16.2, LPAAT-delta, LPAAT4, LPLAT4" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 55.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.9;Inhibitory neurons: 91.5;Late spermatids: 84.0;monocytes: 106.9;Oligodendrocytes: 379.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" 22 "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon, LPLAT5" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708642-6761503 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.4" "Cell type enhanced" "Detected in all" "dendritic cells: 150.0;Glandular and luminal cells: 95.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favorable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 93.7;placenta: 137.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 44.5;Hepatocytes: 28.4;Leydig cells: 139.1;Sertoli cells: 51.7;Smooth muscle cells: 57.7" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enriched" "Detected in many" 4 "midbrain: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.3;Rhabdoid: 6.8" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 230.7;Hofbauer cells: 162.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 59 Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Intellectual disability, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 229.2;Proximal tubular cells: 328.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 228.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 245.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 1 "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" AKAP1 "AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17" ENSG00000121057 "A-kinase anchoring protein 1" Q92667 17 57085092-57121346 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 200.5" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2209.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008620, HPA008691, CAB019286" Supported Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 79: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 1 Mitochondria "CAB019286: , HPA008620: AB_2668104, HPA008691: AB_1078119" "unprognostic (5.52e-2)" "unprognostic (1.83e-1)" "unprognostic (6.96e-3)" "unprognostic (1.78e-1)" "unprognostic (1.79e-2)" "unprognostic (6.38e-2)" "unprognostic (7.19e-2)" "unprognostic (1.48e-2)" "unprognostic (8.14e-2)" "unprognostic (2.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.00e-1)" "prognostic favorable (7.86e-9)" "unprognostic (6.82e-2)" "unprognostic (2.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.38e-1)" AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 28.4;heart muscle: 52.7;retina: 13.2;skeletal muscle: 45.8;tongue: 48.8" "Group enriched" "Detected in many" 5 "Excitatory neurons: 581.4;Inhibitory neurons: 635.2;Oligodendrocyte precursor cells: 387.2;Oligodendrocytes: 1082.0" "Cancer enhanced" "Detected in many" "glioma: 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.4" "Lineage enriched" "Detected in single" 6 "B-cells: 3.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.8" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 34: B-cells - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 1 "CAB001983: , HPA048741: AB_2680506" "unprognostic (1.99e-1)" "unprognostic (9.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.41e-4)" "unprognostic (1.81e-3)" "unprognostic (1.93e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-3)" "unprognostic (3.54e-1)" "unprognostic (3.33e-16)" "unprognostic (8.57e-2)" "unprognostic (1.27e-1)" "unprognostic (5.14e-3)" "unprognostic (1.79e-3)" ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 424.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 292.6;Oligodendrocyte precursor cells: 638.2;Oligodendrocytes: 913.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" Immunity NA NA 1600000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 3 Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" ALDH16A1 MGC10204 ENSG00000161618 "Aldehyde dehydrogenase 16 family member A1" Q8IZ83 19 49453225-49471050 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059488 Approved NA NA 600000 "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 53: Fibroblasts - ECM organization" 2 "HPA059488: AB_2684037" "unprognostic (2.39e-1)" "unprognostic (3.95e-3)" "unprognostic (7.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-3)" "unprognostic (5.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.92e-2)" "unprognostic (4.90e-1)" "unprognostic (1.19e-3)" "unprognostic (4.28e-2)" "unprognostic (1.91e-3)" "unprognostic (2.94e-2)" "unprognostic (4.19e-1)" "unprognostic (1.27e-1)" "unprognostic (5.23e-3)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 246.3;Basal squamous epithelial cells: 281.7;Squamous epithelial cells: 221.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662155-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 70.8;esophagus: 147.9;skin 1: 119.0;vagina: 39.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.3;Glandular and luminal cells: 27.0;Squamous epithelial cells: 63.5;Suprabasal keratinocytes: 47.2;Syncytiotrophoblasts: 18.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "breast cancer: 104.9" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Region enriched" "Detected in single" 8 "olfactory bulb: 1.0" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 365.2;liver: 355.6" "Group enriched" "Detected in many" 5 "Hepatocytes: 540.4;Proximal tubular cells: 777.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 41: Basophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033702-5087379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: AB_2684273" "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favorable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 11.9;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 5 "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" ALG10B KCR1 ENSG00000175548 "ALG10 alpha-1,2-glucosyltransferase B" Q5I7T1 12 38316762-38329721 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (4.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.58e-2)" "unprognostic (7.40e-2)" "unprognostic (8.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.30e-3)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" ALG11 "CDG1P, KIAA0266" ENSG00000253710 "ALG11 alpha-1,2-mannosyltransferase" Q2TAA5 13 52012391-52079232 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047214 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "HPA047214: AB_10961640" "unprognostic (9.21e-2)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (3.04e-2)" "unprognostic (9.15e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" "unprognostic (8.97e-3)" "unprognostic (8.89e-3)" "unprognostic (7.47e-2)" "unprognostic (2.30e-4)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.03e-2)" "unprognostic (9.71e-3)" ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12 alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "HPA003076: AB_2666777, HPA051665: AB_2681566" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (4.39e-3)" "prognostic favorable (6.09e-4)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (4.27e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.21e-1)" "prognostic favorable (3.60e-5)" "unprognostic (1.62e-2)" "unprognostic (3.00e-2)" "unprognostic (9.89e-3)" "unprognostic (6.32e-2)" ALG14 MGC19780 ENSG00000172339 "ALG14 UDP-N-acetylglucosaminyltransferase subunit" Q96F25 1 94974405-95072951 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031829 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" Nucleoli Nucleoplasm "HPA031829: AB_2674062" "unprognostic (7.79e-2)" "unprognostic (3.59e-2)" "unprognostic (1.51e-3)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "unprognostic (6.56e-2)" "unprognostic (4.00e-1)" "unprognostic (2.17e-2)" "unprognostic (3.18e-1)" "unprognostic (2.01e-1)" "unprognostic (7.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (9.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.99e-2)" "unprognostic (1.93e-1)" ALG2 "CDG1I, CDGIi, FLJ14511, hALPG2, NET38" ENSG00000119523 "ALG2 alpha-1,3/1,6-mannosyltransferase" Q9H553 9 99216425-99221942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 101.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041512, HPA041601" Approved Approved "Golgi apparatus" NA No "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus" "HPA041512: AB_10794380, HPA041601: AB_10794302" "unprognostic (8.86e-3)" "unprognostic (4.39e-1)" "unprognostic (2.37e-1)" "prognostic favorable (8.44e-5)" "unprognostic (9.21e-3)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.06e-2)" "unprognostic (5.94e-2)" "unprognostic (3.31e-1)" "unprognostic (3.66e-1)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "prognostic favorable (2.28e-7)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-2)" "unprognostic (4.81e-1)" ALG3 "CDGS4, D16Ertd36e, Not56, NOT56L" ENSG00000214160 "ALG3 alpha-1,3- mannosyltransferase" Q92685 3 184242301-184249548 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 234.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045103 Enhanced NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 10 "HPA045103: AB_10960547" "unprognostic (3.63e-2)" "unprognostic (2.60e-1)" "unprognostic (2.36e-2)" "unprognostic (1.80e-3)" "unprognostic (3.63e-1)" "unprognostic (7.93e-3)" "prognostic unfavorable (1.58e-5)" "prognostic unfavorable (8.67e-5)" "unprognostic (6.18e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-3)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (9.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (5.02e-2)" ALG5 bA421P11.2 ENSG00000120697 "ALG5 dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949738-37000763 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" Cytosol "HPA007989: AB_1078132" "unprognostic (1.87e-1)" "unprognostic (1.73e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.57e-2)" "unprognostic (5.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.46e-2)" "unprognostic (3.51e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.40e-5)" "unprognostic (7.44e-2)" "unprognostic (1.66e-1)" "unprognostic (7.14e-3)" "unprognostic (1.86e-1)" ALG6 ENSG00000088035 "ALG6 alpha-1,3-glucosyltransferase" Q9Y672 1 63367575-63438553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062536, HPA076130" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Spleen - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" "Endoplasmic reticulum" "HPA062536: AB_2684792, HPA076130: " "unprognostic (1.21e-1)" "unprognostic (5.60e-3)" "prognostic favorable (4.86e-4)" "unprognostic (1.59e-1)" "unprognostic (3.45e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (2.07e-1)" "unprognostic (9.81e-3)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (2.63e-6)" "unprognostic (1.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.61e-2)" "unprognostic (3.41e-1)" ALG8 MGC2840 ENSG00000159063 "ALG8 alpha-1,3-glucosyltransferase" Q9BVK2 11 78095244-78139660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Testis - Spermatid development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 8 Nucleoplasm "HPA051898: AB_2681656" "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" ALG9 DIBD1 ENSG00000086848 "ALG9 alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.7;Inhibitory neurons: 30.5;Oligodendrocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" ALK "ALK1, CD246" ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;pituitary gland: 1.2;testis: 1.2" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 262.0;Oligodendrocyte precursor cells: 407.0" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 84.2" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 5 "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 482.0;lung: 177.5;lymphoid tissue: 135.2" "Cell type enhanced" "Detected in many" "dendritic cells: 1294.1;granulocytes: 863.6;Hofbauer cells: 495.3;Langerhans cells: 417.5;Macrophages: 607.8;NK-cells: 339.5;T-cells: 313.8" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9738.9;eosinophil: 4044.4;neutrophil: 4992.0;plasmacytoid DC: 3563.5" "Group enriched" "Detected in all" 8 "dendritic cells: 3563.5;granulocytes: 9738.9" "Cancer enhanced" "Detected in many" "Leukemia: 124.7;lymphoma: 190.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 5 "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442621 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favorable (1.17e-4)" ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 58.8" "Cell type enriched" "Detected in many" 7 "Alveolar cells type 2: 315.4" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 381.2" "Lineage enriched" "Detected in many" 139 "granulocytes: 381.2" "Cancer enhanced" "Detected in many" "Bone cancer: 75.0;testis cancer: 44.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Neutrophils, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA 13000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 72: Alveolar cells - Lung function" 1 Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425545 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.3;Hepatocytes: 133.9;Late spermatids: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA064339, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 62: Hepatocytes - Metabolism" 12 "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: AB_2672869, HPA064339: , HPA077835: AB_2686856" "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 40.2;ovary: 33.4" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 122.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 5.0;liver cancer: 4.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Colon - Mast cells, Liver - Sinusoid Endothelial cells, Pancreas - Exocrine glandular cells, Skin - Mast cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 10 "hippocampal formation: 13.5" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 18: Non-specific - Ribosome" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" 2 Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" AMIGO1 "AMIGO, KIAA1163" ENSG00000181754 "Adhesion molecule with Ig like domain 1" Q86WK6 1 109504178-109509738 "Predicted membrane proteins, Transporters" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.4;Horizontal cells: 18.3;Inhibitory neurons: 15.2;Oocytes: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046152, HPA062080" Approved Approved Vesicles NA NA "Cluster 27: T-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 34 Vesicles "HPA046152: AB_2679559, HPA062080: " "unprognostic (1.35e-1)" "unprognostic (3.94e-1)" "unprognostic (2.32e-2)" "unprognostic (4.78e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.16e-3)" "unprognostic (3.11e-1)" "unprognostic (9.06e-3)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 34.5;Bipolar cells: 48.5;Breast myoepithelial cells: 41.6;Enteroendocrine cells: 34.5;Glandular and luminal cells: 66.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 75.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 207.1" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 11: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" 2 "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 81.3;kidney: 38.7;liver: 36.9" "Group enriched" "Detected in many" 4 "Distal enterocytes: 671.4;Proximal enterocytes: 1890.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;Gastric cancer: 6.2;liver cancer: 6.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" Transport NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 3 Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 193.2;Inhibitory neurons: 205.0;Oligodendrocytes: 243.4;Oocytes: 574.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Uncertain Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 65: Neurons - Synaptic function" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" ANKLE1 "ANKRD41, FLJ39369, LEMD6" ENSG00000160117 "Ankyrin repeat and LEM domain containing 1" Q8NAG6 19 17281645-17287646 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 24.4" "Cell type enriched" "Detected in some" 20 "Erythroid cells: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 25.7;lymphoma: 28.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA026789, HPA073498" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 6: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA026789: AB_10611675, HPA073498: AB_2686612" "unprognostic (5.66e-2)" "unprognostic (2.21e-1)" "unprognostic (6.90e-2)" "prognostic unfavorable (4.86e-5)" "unprognostic (2.73e-1)" "unprognostic (1.72e-3)" "unprognostic (2.19e-2)" "unprognostic (2.09e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "unprognostic (7.89e-4)" "unprognostic (5.86e-2)" "unprognostic (0.00e+0)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (2.00e-3)" "unprognostic (4.30e-2)" ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Endoplasmic reticulum, Plasma membrane" "HPA003602: AB_1858349, HPA074838: " "unprognostic (4.43e-2)" "unprognostic (6.92e-2)" "unprognostic (7.97e-2)" "unprognostic (9.84e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.97e-6)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (4.76e-2)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (6.92e-3)" "unprognostic (2.09e-1)" ANKRD29 FLJ25053 ENSG00000154065 "Ankyrin repeat domain 29" Q8N6D5 18 23598926-23662911 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 163.7;Alveolar cells type 1: 271.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041272, HPA049419" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "Nucleoplasm, Nuclear bodies" "HPA041272: AB_2677387, HPA049419: AB_2680757" "unprognostic (4.52e-3)" "unprognostic (8.37e-2)" "unprognostic (7.04e-2)" "unprognostic (1.78e-1)" "unprognostic (2.01e-3)" "prognostic favorable (1.92e-5)" "unprognostic (3.29e-2)" "prognostic favorable (5.98e-5)" "unprognostic (1.11e-1)" "unprognostic (1.93e-2)" "unprognostic (3.83e-2)" "unprognostic (3.54e-1)" "prognostic favorable (7.20e-5)" "unprognostic (1.10e-2)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" "unprognostic (1.64e-5)" ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Cytosol "HPA013758: AB_10962626" "unprognostic (3.71e-3)" "unprognostic (9.01e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (8.84e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "unprognostic (8.08e-3)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (6.29e-3)" ANKS1A "ANKS1, KIAA0229" ENSG00000064999 "Ankyrin repeat and sterile alpha motif domain containing 1A" Q92625 6 34889255-35091406 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.8;Inhibitory neurons: 154.2;Microglial cells: 161.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 4.4;granulocytes: 1.2;monocytes: 1.8" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036768, HPA036769" Approved Approved Nucleoplasm,Cytosol NA NA 17000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" 3 Nucleoplasm Cytosol "HPA036768: AB_10670923, HPA036769: AB_10672473" "unprognostic (3.75e-2)" "unprognostic (2.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.79e-3)" "unprognostic (5.73e-2)" "prognostic favorable (7.48e-4)" "unprognostic (1.18e-3)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "prognostic favorable (8.05e-5)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.23e-2)" "unprognostic (7.80e-2)" ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 69985907-70189530 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 84.1;seminal vesicle: 85.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 123.4;Breast myoepithelial cells: 71.4;Hepatocytes: 118.7;Late spermatids: 79.5;Serous glandular cells: 82.6;Smooth muscle cells: 45.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 62.2;pancreatic cancer: 72.4" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 8.8" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 93.8;Oocytes: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 199.6" "Group enriched" "Detected in some" 4 "Late spermatids: 285.2;Microglial cells: 136.9;Rod photoreceptor cells: 183.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 7.6" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" ANO3 "C11orf25, DYT23, GENX-3947, TMEM16C" ENSG00000134343 "Anoctamin 3" Q9BYT9 11 26188842-26663289 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "brain: 56.7;epididymis: 56.0" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 195.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 129.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Rhabdoid: 8.3" "Testis - Early spermatids" "Region enhanced" "Detected in all" "basal ganglia: 158.9" "Region enriched" "Detected in all" 7 "basal ganglia: 211.0" HPA041629 Uncertain NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA041629: AB_10793969" "unprognostic (7.01e-3)" "unprognostic (4.31e-1)" "unprognostic (2.94e-1)" "unprognostic (9.29e-2)" "unprognostic (9.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-2)" "unprognostic (1.66e-1)" "unprognostic (2.45e-2)" "unprognostic (7.02e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-4)" "unprognostic (9.48e-3)" "unprognostic (3.50e-2)" "unprognostic (4.33e-1)" "unprognostic (4.01e-1)" ANO4 "FLJ34221, FLJ34272, FLJ35277, TMEM16D" ENSG00000151572 "Anoctamin 4" Q32M45 12 100717526-101128641 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 11.6;cervix: 7.4;seminal vesicle: 7.8" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 514.3;Oligodendrocyte precursor cells: 259.9;Oligodendrocytes: 757.8" "Cancer enhanced" "Detected in some" "renal cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.8;testis cancer: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053412 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "HPA053412: AB_2682140" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "unprognostic (4.58e-2)" "unprognostic (1.04e-1)" "unprognostic (1.20e-2)" "unprognostic (2.02e-1)" "unprognostic (3.76e-2)" "unprognostic (1.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (4.72e-1)" "unprognostic (6.54e-2)" "prognostic favorable (5.48e-5)" "unprognostic (1.16e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.41e-1)" ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21782659-22283567 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 23.4;parathyroid gland: 16.6;skeletal muscle: 63.3;tongue: 47.8" "Group enriched" "Detected in many" 6 "Astrocytes: 64.4;Cardiomyocytes: 97.8;Excitatory neurons: 161.2;Inhibitory neurons: 130.7;Oligodendrocyte precursor cells: 76.4;Skeletal myocytes: 80.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.4" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA058857: AB_2683835" "unprognostic (5.25e-3)" "unprognostic (1.36e-3)" "unprognostic (2.43e-1)" "unprognostic (7.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.85e-2)" "unprognostic (8.17e-3)" "unprognostic (2.30e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.54e-4)" "unprognostic (8.55e-2)" "prognostic favorable (2.50e-7)" "unprognostic (3.65e-3)" "unprognostic (2.84e-1)" "unprognostic (2.77e-4)" "unprognostic (7.94e-2)" ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Platelets - Hemostasis" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" ANO7 "IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G" ENSG00000146205 "Anoctamin 7" Q6IWH7 2 241188509-241225976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;prostate: 68.5;stomach 1: 27.7" "Group enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 66.6;Intestinal goblet cells: 67.3;Prostatic glandular cells: 68.0" "Cancer enriched" "Detected in many" 19 "prostate cancer: 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 6.6" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" HPA078464 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA078464: " "unprognostic (1.93e-2)" "unprognostic (3.45e-3)" "unprognostic (1.09e-3)" "unprognostic (5.13e-2)" "unprognostic (1.35e-2)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (8.45e-2)" "unprognostic (2.90e-2)" "unprognostic (4.94e-2)" "unprognostic (4.82e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.53e-2)" ANO8 "KIAA1623, TMEM16H" ENSG00000074855 "Anoctamin 8" Q9HCE9 19 17323223-17334855 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 69.4;Inhibitory neurons: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049206 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 47: Astrocytes - Unknown function" "HPA049206: AB_2680675" "unprognostic (5.12e-2)" "unprognostic (2.79e-1)" "unprognostic (1.59e-1)" "unprognostic (3.07e-1)" "unprognostic (2.91e-1)" "unprognostic (2.20e-3)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (3.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (5.89e-2)" "unprognostic (3.05e-3)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.48e-2)" "unprognostic (4.59e-2)" ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.3;skin 1: 27.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 67.5;Intestinal goblet cells: 47.0;Paneth cells: 31.3;Proximal enterocytes: 75.1;Undifferentiated cells: 32.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.4" "Adipose subcutaneous - T-cells, Liver - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "HPA039948: AB_2676765, HPA040112: " "unprognostic (3.62e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (1.62e-1)" "unprognostic (1.41e-2)" "unprognostic (8.93e-2)" "unprognostic (6.98e-2)" "unprognostic (8.94e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-3)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (1.91e-2)" "unprognostic (1.18e-2)" "unprognostic (2.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (8.81e-4)" ANPEP "AP-N, CD13, gp150, hAPN, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2318.1;pancreas: 655.5" "Cell type enriched" "Detected in many" 12 "Proximal enterocytes: 5896.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 19.2;thalamus: 38.8" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 455.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" ANTKMT "C16orf24, FAM173A, MGC2494" ENSG00000103254 "Adenine nucleotide translocase lysine methyltransferase" Q9BQD7 16 720581-722590 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 257.2;Late spermatids: 473.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046262 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 10 Cytosol "HPA046262: AB_10963070" "unprognostic (3.94e-2)" "unprognostic (8.78e-2)" "unprognostic (1.55e-1)" "unprognostic (2.61e-1)" "unprognostic (6.54e-2)" "prognostic favorable (8.88e-4)" "unprognostic (2.11e-1)" "unprognostic (4.49e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (4.02e-2)" "unprognostic (5.70e-2)" "prognostic favorable (4.24e-5)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (9.28e-2)" "unprognostic (3.60e-3)" ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 123.9;Endometrial stromal cells: 81.6;Oligodendrocyte precursor cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 349.2" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" Receptor NA NA 11000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" AP5S1 "C20orf29, FLJ11168" ENSG00000125843 "Adaptor related protein complex 5 subunit sigma 1" Q9NUS5 20 3820524-3828838 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034200, HPA043533, HPA048244" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "CAB034200: AB_1564201, HPA043533: AB_2732507, HPA048244: AB_2680328" "unprognostic (1.07e-2)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (2.74e-2)" "unprognostic (1.34e-1)" "unprognostic (2.05e-2)" "unprognostic (5.49e-2)" "unprognostic (7.76e-2)" "unprognostic (1.33e-1)" "unprognostic (8.91e-2)" "unprognostic (5.15e-3)" "unprognostic (8.17e-2)" "prognostic favorable (5.53e-5)" "unprognostic (2.92e-1)" "unprognostic (1.62e-1)" "unprognostic (6.09e-3)" "unprognostic (5.08e-2)" APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 18.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.6;Breast myoepithelial cells: 6.1;Fibroblasts: 3.0;Oligodendrocyte precursor cells: 5.7;Pancreatic endocrine cells: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 44.8" "Heart muscle - Fibroblasts, Pancreas - Beta cells" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 38: Salivary gland - Salivary secretion" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" 3 Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" APH1A "APH-1A, CGI-78" ENSG00000117362 "Aph-1 homolog A, gamma-secretase subunit" Q96BI3 1 150265399-150269580 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037272 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 21 "CAB037272: AB_476776" "unprognostic (1.00e-1)" "unprognostic (5.55e-2)" "unprognostic (8.84e-2)" "unprognostic (1.20e-3)" "unprognostic (4.92e-2)" "unprognostic (3.55e-2)" "unprognostic (2.75e-3)" "unprognostic (4.42e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.53e-1)" "unprognostic (6.99e-2)" "unprognostic (4.48e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.87e-1)" APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237250 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.6;lymphoid tissue: 105.0;placenta: 89.7" "Group enriched" "Detected in some" 8 "Adipocytes: 67.1;Endothelial cells: 42.4" "Cancer enhanced" "Detected in all" "glioma: 50.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 24.1" "Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025842 Approved NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB025842: " "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-1)" "unprognostic (6.68e-3)" "unprognostic (1.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.72e-1)" "unprognostic (1.77e-3)" "unprognostic (3.27e-2)" "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" APLP1 APLP ENSG00000105290 "Amyloid beta precursor like protein 1" P51693 19 35867899-35879792 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Endocytosis" Heparin-binding Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 1106.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 53.6;Horizontal cells: 86.2;Oligodendrocytes: 429.4" "Cancer enhanced" "Detected in many" "glioma: 63.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 146.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028970, HPA028971" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 6400000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" 4 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA028970: AB_2672847, HPA028971: AB_10601334" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (9.36e-3)" "prognostic unfavorable (3.87e-4)" "unprognostic (7.32e-3)" "unprognostic (1.26e-2)" "unprognostic (1.04e-3)" "unprognostic (2.24e-2)" "unprognostic (4.98e-2)" "unprognostic (6.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.57e-11)" "unprognostic (1.38e-3)" "unprognostic (7.12e-2)" "unprognostic (5.43e-2)" "prognostic unfavorable (2.65e-5)" APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved "Golgi apparatus,Vesicles" NA NA 1500000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Bipolar cells - Visual perception" 3 "Golgi apparatus, Vesicles" "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 306.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 319.0;NK-cells: 227.1;Syncytiotrophoblasts: 833.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 682.8;NK-cells: 344.4;T-cells: 368.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" APOC4-APOC2 ENSG00000224916 "APOC4-APOC2 readthrough (NMD candidate)" 19 44942238-44949565 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 235 "liver: 2166.8" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 97.9" "Cancer enriched" "Detected in some" 17 "liver cancer: 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055877 Supported NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 70: DU4475 - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "HPA055877: AB_2682953" "unprognostic (1.45e-1)" "unprognostic (4.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (4.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.01e-4)" "unprognostic (2.28e-1)" "unprognostic (2.88e-1)" "unprognostic (5.95e-2)" "unprognostic (1.68e-2)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 174.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 107.3;Glandular and luminal cells: 219.4;Hepatocytes: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 244.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" Apolipoprotein NA NA 1640000000 9200000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Liver - Plasma proteins" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" APOL2 APOL-II ENSG00000128335 "Apolipoprotein L2" Q9BQE5 22 36226209-36239954 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.7;Hepatocytes: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA001078, CAB026695" Supported NA NA 29000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Glandular & Luminal cells - Unknown function" 26 "CAB026695: , HPA001078: AB_10602432" "unprognostic (4.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.50e-2)" "unprognostic (4.26e-3)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.38e-2)" "unprognostic (7.39e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.22e-7)" "unprognostic (1.80e-1)" "unprognostic (6.79e-2)" "unprognostic (2.66e-2)" "prognostic favorable (5.06e-6)" APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 15.6;Glandular and luminal cells: 53.1;Prostatic glandular cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 15.5;lymphoma: 4.5" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" Apolipoprotein NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.3;NK-cells: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 7 "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: AB_10670037, HPA029167: AB_10670832" "unprognostic (7.25e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-2)" "unprognostic (8.29e-2)" "unprognostic (3.76e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.46e-1)" "unprognostic (6.65e-3)" "unprognostic (2.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "prognostic favorable (6.61e-4)" APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.2" "Group enriched" "Detected in many" 5 "Adipocytes: 761.2;Endothelial cells: 249.3;Lymphatic endothelial cells: 336.7;Smooth muscle cells: 191.3" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 9 "skin cancer: 43.6" "Breast - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Enhanced "Nucleoplasm,Plasma membrane" No No "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 105.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 110.6;Oocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" Apolipoprotein NA NA 2210000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" APP "AD1, alpha-sAPP" ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880535-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 810.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 36.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 36.4" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Cell adhesion" NA NA 26000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 312 "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 786.7" "Group enriched" "Detected in many" 6 "Adipocytes: 881.1;Alveolar cells type 1: 406.1;Alveolar cells type 2: 408.7;Cholangiocytes: 333.9;Endothelial cells: 689.9;Mesothelial cells: 636.1;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 50.3" "Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 46.6" "Region enriched" "Detected in many" 4 "spinal cord: 29.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 106 "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 66.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Ciliated cells: 2.7;Erythroid cells: 1.1;granulocytes: 5.0;Sertoli cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 1.5;Neuroblastoma: 1.1" "Testis - Sertoli cells" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 17 "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" AQP11 AQPX1 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.8;liver: 15.6" "Cell type enhanced" "Detected in many" "Early spermatids: 46.7;Hepatocytes: 37.4;Late spermatids: 63.7;Proximal enterocytes: 33.3;Spermatocytes: 50.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077460 Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Plasma membrane" Vesicles "HPA077460: " "unprognostic (4.95e-2)" "unprognostic (7.61e-2)" "unprognostic (2.15e-2)" "unprognostic (9.62e-5)" "unprognostic (2.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "prognostic favorable (9.89e-4)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (2.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.66e-3)" AQP12A AQP12 ENSG00000184945 "Aquaporin 12A" Q8IXF9 2 240691866-240698483 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 326 "pancreas: 101.9" "Cell type enhanced" "Detected in single" "Proximal enterocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042216 Supported NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "HPA042216: AB_2677905" "unprognostic (9.82e-2)" "unprognostic (1.63e-2)" "unprognostic (9.48e-2)" "unprognostic (2.14e-1)" AQP12B INSSA3 ENSG00000185176 "Aquaporin 12B" A6NM10 2 240676418-240682906 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 328 "pancreas: 203.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" HPA042216 Supported NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" "HPA042216: AB_2677905" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.41e-1)" AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 91 "kidney: 373.4;seminal vesicle: 205.2" "Cell type enriched" "Detected in some" 17 "Collecting duct cells: 3224.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;Gastric cancer: 1.2" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" 33 "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1483.2;skin 1: 563.9;urinary bladder: 662.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1556.2;Basal squamous epithelial cells: 1011.0;Collecting duct cells: 1073.6;Squamous epithelial cells: 2365.1;Suprabasal keratinocytes: 2153.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Region enhanced" "Detected in all" "pons: 47.2" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 182.0;T-reg: 205.9" "Lineage enriched" "Detected in many" 18 "T-cells: 205.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.6" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 23 "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" AQP4 "AQP-4, hAQP4, MIWC" ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 367.2;lung: 111.3" "Group enriched" "Detected in many" 11 "Alveolar cells type 1: 422.7;Alveolar cells type 2: 333.2;Astrocytes: 462.6;Muller glia cells: 197.3" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 2.5;Rhabdoid: 1.7" "Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Alveolar cells - Lung function" 2 "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 604.8;testis: 215.9" "Group enriched" "Detected in many" 6 "Early spermatids: 1377.0;Late spermatids: 4261.2;Serous glandular cells: 1171.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.1;Gastric cancer: 24.2" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "kidney: 51.2" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Club cells: 1.5;Collecting duct cells: 1.9;Distal tubular cells: 3.1;Ionocytes: 5.5;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.5" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 264 "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" AQP8 ENSG00000103375 "Aquaporin 8" O94778 16 25215731-25228932 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 485 "intestine: 318.6;pancreas: 1239.8" "Cell type enriched" "Detected in some" 63 "Distal enterocytes: 1875.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.4;pancreatic cancer: 15.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046259 Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 11 "HPA046259: AB_10960494" "unprognostic (8.75e-2)" "unprognostic (2.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.93e-2)" "unprognostic (8.67e-2)" "unprognostic (3.34e-3)" "unprognostic (8.47e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-1)" "unprognostic (2.05e-2)" "unprognostic (8.23e-2)" "unprognostic (1.06e-2)" "unprognostic (2.67e-2)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (3.71e-2)" AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 681.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 277.8;Hofbauer cells: 71.4;Kupffer cells: 51.3;Macrophages: 89.1;monocytes: 342.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 28.1" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1165.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 1165.9" "Cancer enriched" "Detected in single" 9 "lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA074762, CAB075684" Enhanced NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 18 "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969742 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 107.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040624, HPA055647" Enhanced Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" 15 Nucleoplasm "HPA040624: AB_2677050, HPA055647: AB_2682874" "unprognostic (1.73e-1)" "unprognostic (3.71e-2)" "unprognostic (2.97e-1)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-2)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "prognostic favorable (4.83e-4)" "unprognostic (2.97e-1)" "unprognostic (2.47e-1)" "unprognostic (3.84e-1)" "unprognostic (3.13e-2)" AREG "AR, AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 128.6;placenta: 317.5;urinary bladder: 140.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2219.4;dendritic cells: 3645.0;granulocytes: 4608.4;monocytes: 4647.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 67.1" "Region enhanced" "Detected in some" "choroid plexus: 3.2" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 543.3" "Colon - Neutrophils, Testis - Early spermatids" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in all" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA 1520000 "Cluster 22: Eosinophils - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 3 Mitochondria "CAB023519: AB_2060673, HPA008720: AB_1844978" "unprognostic (1.44e-2)" "unprognostic (1.84e-3)" "unprognostic (3.36e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.90e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (8.32e-5)" "unprognostic (2.56e-2)" "unprognostic (2.49e-3)" "unprognostic (2.40e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (6.83e-3)" AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713117 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051306 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 74: Neutrophils - Degranulation" 1 "HPA051306: AB_2681433" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (1.92e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.58e-3)" "unprognostic (9.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-1)" "prognostic favorable (4.67e-6)" "unprognostic (6.73e-2)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (7.18e-2)" ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 2 Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" ARHGAP11A-SCG5 ENSG00000288864 "ARHGAP11A-SCG5 readthrough" 15 32613860-32697095 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA013136, HPA074618" Uncertain NA NA "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "HPA013136: AB_1856657, HPA074618: AB_2732262" ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 225.1;Excitatory neurons: 591.4;Inhibitory neurons: 250.7;Late spermatids: 210.9;Microglial cells: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "neutrophil: 24.8;NK-cell: 9.9" "Group enriched" "Detected in many" 4 "granulocytes: 24.8;NK-cells: 9.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 3 Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" ARHGAP42 "AD031, FLJ32810, GRAF3, TMEM133" ENSG00000165895 "Rho GTPase activating protein 42" A6NI28 11 100687288-100993941 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 30.6" "Cell type enhanced" "Detected in many" "Astrocytes: 97.5;Early spermatids: 64.5;Oligodendrocyte precursor cells: 212.2;Rod photoreceptor cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039924, HPA060528" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Nuclear speckles" Cytosol "HPA039924: AB_10674428, HPA060528: AB_2684308" "unprognostic (1.04e-1)" "unprognostic (9.84e-2)" "unprognostic (3.21e-3)" "unprognostic (2.74e-1)" "unprognostic (1.50e-2)" "unprognostic (4.17e-2)" "unprognostic (1.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.30e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.32e-1)" "unprognostic (1.75e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (8.45e-2)" "unprognostic (1.03e-1)" ARL10 ARL10A ENSG00000175414 "ADP ribosylation factor like GTPase 10" Q8N8L6 5 176365487-176401865 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 16.9;Inhibitory neurons: 17.4;Oligodendrocyte precursor cells: 24.5;Oligodendrocytes: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047044 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "HPA047044: AB_2679915" "unprognostic (2.50e-2)" "unprognostic (4.77e-2)" "unprognostic (6.90e-2)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.37e-1)" "unprognostic (6.31e-2)" "unprognostic (6.00e-3)" "unprognostic (2.78e-1)" "unprognostic (9.29e-2)" "unprognostic (5.92e-3)" "unprognostic (7.96e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-2)" "unprognostic (4.33e-2)" ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA045307 Uncertain Supported "Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 60 "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" ARL6IP5 "DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b" ENSG00000144746 "ADP ribosylation factor like GTPase 6 interacting protein 5" O75915 3 69084937-69106092 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015540, CAB019321" Supported Approved "Endoplasmic reticulum" NA NA 1100000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Endoplasmic reticulum" "CAB019321: , HPA015540: AB_1852061" "unprognostic (8.01e-2)" "unprognostic (1.71e-1)" "unprognostic (8.09e-2)" "unprognostic (1.51e-3)" "unprognostic (2.65e-1)" "unprognostic (3.51e-1)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (3.06e-1)" "unprognostic (3.72e-3)" "unprognostic (1.31e-2)" "unprognostic (7.23e-2)" "unprognostic (2.05e-3)" "unprognostic (3.60e-1)" "unprognostic (4.44e-2)" "unprognostic (3.42e-2)" "unprognostic (1.31e-2)" ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717647-152762396 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 55.5" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 155.3;Extravillous trophoblasts: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 429.8;eosinophil: 302.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 429.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 4: Extravillous trophoblasts - Unknown function" 13 "Nuclear membrane" Cytosol "HPA014743: AB_1845030" "unprognostic (4.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "unprognostic (9.86e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (5.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.14e-1)" "unprognostic (2.67e-1)" "unprognostic (4.57e-1)" "unprognostic (7.39e-2)" ARMC10 "MGC3195, SVH" ENSG00000170632 "Armadillo repeat containing 10" Q8N2F6 7 103074881-103099759 "Predicted intracellular proteins, Predicted membrane proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011036, HPA011057" Enhanced Enhanced Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 64: Non-specific - Ribosome" Mitochondria "HPA011036: AB_1080139, HPA011057: AB_1080137" "unprognostic (7.03e-3)" "unprognostic (2.44e-1)" "unprognostic (8.18e-2)" "unprognostic (3.53e-1)" "prognostic unfavorable (8.90e-6)" "unprognostic (3.85e-3)" "prognostic unfavorable (3.58e-4)" "unprognostic (5.57e-2)" "unprognostic (3.49e-2)" "unprognostic (7.90e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (1.02e-1)" "unprognostic (5.78e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.14e-2)" "unprognostic (5.67e-2)" ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.5;Ovarian stromal cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Sarcoma: 28.9" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 6: Ovarian stromal cells - Transcription" 6 Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: AB_10600781" "unprognostic (2.31e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-3)" "unprognostic (2.13e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.32e-5)" "unprognostic (1.02e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-3)" "unprognostic (8.77e-2)" "unprognostic (2.12e-2)" "unprognostic (1.09e-2)" ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 151.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 50.3;Cardiomyocytes: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 83.2" "Skeletal muscle - Fibroblasts, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 34: B-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 30: Granulocytes - Unknown function" 3 Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: AB_1078206, HPA000967: AB_1078208, HPA001530: AB_2666349" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (5.23e-2)" "unprognostic (8.69e-3)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (9.72e-3)" "unprognostic (2.19e-2)" "unprognostic (4.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-2)" "prognostic favorable (1.55e-5)" "unprognostic (3.29e-2)" "unprognostic (3.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.55e-2)" ARMCX6 "FLJ20811, GASP10" ENSG00000198960 "Armadillo repeat containing X-linked 6" Q7L4S7 X 101615118-101618001 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.1;Gastric mucus-secreting cells: 14.1;Plasma cells: 14.7;Squamous epithelial cells: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043030, HPA048125" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" Cytosol "Nucleoplasm, Nuclear membrane" "HPA043030: AB_2678277, HPA048125: AB_2680275" "unprognostic (1.20e-1)" "unprognostic (2.80e-1)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.80e-2)" "unprognostic (1.73e-3)" "unprognostic (1.92e-3)" "unprognostic (4.13e-2)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (3.31e-1)" "unprognostic (3.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (7.82e-3)" "unprognostic (2.38e-2)" ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.0" "Cell type enhanced" "Detected in many" "Astrocytes: 44.0;Excitatory neurons: 35.9;Inhibitory neurons: 36.1;Microglial cells: 30.4;Oligodendrocyte precursor cells: 62.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Lung - Fibroblast_2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" ARSD ASD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" ARSF ASF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;kidney: 7.3;skin 1: 5.5" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Inhibitory neurons: 4.4;Oligodendrocyte precursor cells: 2.4;Proximal tubular cells: 7.1;Serous glandular cells: 4.4" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA000549 Approved Vesicles,Cytosol "Secreted in other tissues" Enzyme NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Vesicles, Cytosol" "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934045-2968475 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.3;liver: 88.3;pancreas: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.6;Ductal cells: 29.7;Enteroendocrine cells: 41.0;Hepatocytes: 64.9;Paneth cells: 46.8;Proximal enterocytes: 47.7;Proximal tubular cells: 77.6;Undifferentiated cells: 56.9" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.8;liver cancer: 33.4" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" ART1 "ART2, ARTC1, CD296" ENSG00000129744 "ADP-ribosyltransferase 1" P52961 11 3645128-3664416 "CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "skeletal muscle: 45.7;tongue: 35.3" "Cell type enhanced" "Detected in single" "Microglial cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051148 Uncertain NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 47: Astrocytes - Unknown function" "HPA051148: AB_2681363" "unprognostic (3.73e-1)" "unprognostic (4.58e-2)" "unprognostic (3.12e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" ART3 ARTC3 ENSG00000156219 "ADP-ribosyltransferase 3 (inactive)" Q13508 4 76011184-76114048 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 65.2;skeletal muscle: 191.5;testis: 89.6;tongue: 72.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 75.1;Skeletal myocytes: 247.9;Spermatocytes: 253.1" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "breast cancer: 6.9;skin cancer: 17.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA011268 Enhanced "Intracellular and membrane" Enzyme NA NA 48000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA011268: AB_1845059" "unprognostic (2.45e-1)" "unprognostic (2.84e-2)" "unprognostic (3.12e-2)" "unprognostic (2.77e-3)" "unprognostic (4.53e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.85e-4)" "unprognostic (2.35e-1)" "unprognostic (5.10e-2)" "unprognostic (1.64e-2)" "unprognostic (2.95e-1)" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (6.61e-3)" ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 51.6;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.4;Endothelial cells: 15.2;Erythroid cells: 36.2;Hepatocytes: 27.2;Lymphatic endothelial cells: 52.6;Rod photoreceptor cells: 12.6" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 11.7" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" Enzyme NA NA 17000000 "Cluster 83: Liver - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" ARV1 ENSG00000173409 "ARV1 homolog, fatty acid homeostasis modulator" Q9H2C2 1 230978981-231000733 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035709 Approved Uncertain Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 11 Vesicles "HPA035709: AB_2674744" "unprognostic (2.32e-1)" "unprognostic (4.69e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (9.95e-2)" "unprognostic (5.66e-2)" "prognostic favorable (3.27e-5)" "unprognostic (1.37e-1)" "unprognostic (1.12e-2)" "unprognostic (9.57e-2)" "unprognostic (9.82e-2)" "unprognostic (2.31e-1)" "unprognostic (4.82e-1)" "unprognostic (5.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.12e-3)" ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236193459-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "heart muscle: 6.8;skeletal muscle: 11.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.6;Excitatory neurons: 2.8;Oocytes: 2.2;Skeletal myocytes: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" "unprognostic (1.12e-1)" "unprognostic (7.33e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-6)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 209.4;tongue: 64.5" "Group enriched" "Detected in some" 8 "Late spermatids: 302.0;Skeletal myocytes: 228.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;prostate cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 16.0;Sarcoma: 23.3" "Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Late spermatids - Spermatogenesis" "Plasma membrane" "HPA028870: AB_10611679" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.90e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" "unprognostic (6.80e-3)" ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "liver: 819.9" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 764.0" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;myeloid DC: 64.9" "Group enriched" "Detected in many" 52 "dendritic cells: 64.9;monocytes: 110.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 99.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Hepatocytes, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 35.1" "Cell type enhanced" "Detected in some" "Astrocytes: 29.7;Inhibitory neurons: 15.6;Oligodendrocyte precursor cells: 60.8;Oligodendrocytes: 10.4" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" ASIC2 "ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG" ENSG00000108684 "Acid sensing ion channel subunit 2" Q16515 17 33013087-34174964 "Plasma proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.9;cervix: 3.3;endometrium 1: 3.3;retina: 4.4" "Group enriched" "Detected in some" 8 "Excitatory neurons: 1722.9;Inhibitory neurons: 640.8" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.9;Neuroblastoma: 1.7" "Skin - Fibroblast_1, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052112 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA052112: AB_2681733" "unprognostic (3.40e-1)" "unprognostic (2.45e-2)" "unprognostic (8.50e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-3)" "unprognostic (5.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" ASIC3 "ACCN3, DRASIC, TNaC1" ENSG00000213199 "Acid sensing ion channel subunit 3" Q9UHC3 7 151048292-151052756 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 61.1" "Group enriched" "Detected in many" 4 "glioma: 3.1;testis cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049155, HPA054805" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA049155: AB_2680657, HPA054805: AB_2732588" "unprognostic (8.71e-3)" "unprognostic (1.09e-1)" "unprognostic (1.92e-4)" "unprognostic (2.73e-1)" "unprognostic (7.06e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.42e-1)" "unprognostic (4.45e-2)" "unprognostic (8.64e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-12)" "unprognostic (1.49e-2)" "unprognostic (7.38e-2)" "unprognostic (1.65e-2)" "unprognostic (5.31e-3)" ASIC4 "ACCN4, BNAC4" ENSG00000072182 "Acid sensing ion channel subunit family member 4" Q96FT7 2 219514170-219538772 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.0;pituitary gland: 21.5;retina: 6.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 208.1;Cone photoreceptor cells: 66.3;Horizontal cells: 34.6;Oligodendrocyte precursor cells: 36.8" "Cancer enriched" "Detected in single" 38 "glioma: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 2.4;Neuroblastoma: 4.7;Rhabdoid: 1.4" "Region enhanced" "Detected in many" "basal ganglia: 73.3" "Low region specificity" "Detected in many" HPA036042 Approved "Golgi apparatus" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 25: Bipolar cells - Visual perception" "Golgi apparatus" "HPA036042: AB_10672998" "unprognostic (3.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.55e-1)" "unprognostic (1.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.74e-2)" "unprognostic (3.04e-2)" "unprognostic (2.54e-1)" "unprognostic (6.53e-2)" "unprognostic (1.90e-2)" "unprognostic (9.46e-3)" "unprognostic (1.88e-1)" "unprognostic (7.80e-8)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (5.51e-1)" "unprognostic (2.48e-2)" ASIC5 "ACCN5, HINAC, INAC" ENSG00000256394 "Acid sensing ion channel subunit family member 5" Q9NY37 4 155829729-155866277 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "intestine: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014903, HPA029444" Approved NA NA "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" "HPA014903: AB_1844498, HPA029444: AB_10611671" "unprognostic (8.52e-5)" "unprognostic (2.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 372.0" "Cell type enhanced" "Detected in all" "Astrocytes: 347.7;Muller glia cells: 388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 1 "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" ASPHD1 ENSG00000174939 "Aspartate beta-hydroxylase domain containing 1" Q5U4P2 16 29900375-29919864 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 143.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.5;Enteroendocrine cells: 36.2;Gastric mucus-secreting cells: 29.5;Horizontal cells: 29.6;Mesothelial cells: 72.3;Oligodendrocytes: 27.3;Pancreatic endocrine cells: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045175 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA045175: AB_10959899" "unprognostic (1.58e-1)" "unprognostic (5.50e-2)" "unprognostic (4.74e-3)" "unprognostic (2.20e-3)" "unprognostic (1.34e-3)" "unprognostic (6.96e-2)" "unprognostic (5.75e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (8.37e-2)" "prognostic favorable (7.38e-4)" "unprognostic (5.55e-2)" "unprognostic (6.17e-2)" "unprognostic (1.97e-2)" "unprognostic (1.90e-1)" "unprognostic (2.97e-1)" "unprognostic (9.03e-2)" ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.0;skin 1: 10.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.8;Early spermatids: 13.6;Excitatory neurons: 13.7;Extravillous trophoblasts: 14.7;Late spermatids: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.2;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 11: Late spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" ASTN1 ASTN ENSG00000152092 "Astrotactin 1" O14525 1 176857302-177164973 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 14.4;brain: 38.7;retina: 13.6" "Group enriched" "Detected in some" 7 "Astrocytes: 181.4;Excitatory neurons: 211.3;Inhibitory neurons: 263.8;Oligodendrocyte precursor cells: 262.7" "Cancer enriched" "Detected in some" 14 "glioma: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.4;Neuroblastoma: 4.6" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074112 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus, Vesicles" "HPA074112: AB_2686662" "unprognostic (4.41e-3)" "unprognostic (1.48e-2)" "unprognostic (4.03e-1)" "unprognostic (1.31e-1)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (2.03e-4)" "unprognostic (3.86e-3)" "unprognostic (1.08e-1)" "unprognostic (4.36e-1)" "unprognostic (1.67e-3)" "unprognostic (1.98e-1)" "unprognostic (6.77e-2)" "unprognostic (4.74e-3)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (1.16e-1)" ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 336.3;Excitatory neurons: 357.4;Inhibitory neurons: 970.9;Late spermatids: 230.0;Oligodendrocyte precursor cells: 844.7;Oligodendrocytes: 210.2" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 39: T-cells - T-cell receptor" "Cluster 30: Heart muscle - Heart development" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" ASZ1 "ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3" ENSG00000154438 "Ankyrin repeat, SAM and basic leucine zipper domain containing 1" Q8WWH4 7 117363222-117428123 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "testis: 10.4" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 72.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA020558 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Testis - Spermatid development" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Spermatocytes - Spermatogenesis" 10 Cytosol Nucleoplasm "HPA020558: AB_1845123" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.42e-1)" ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Early spermatids: 846.9;Late spermatids: 1889.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005935 Approved NA NA 46000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" 2 "HPA005935: AB_2667472" "unprognostic (1.31e-1)" "unprognostic (5.15e-3)" "unprognostic (3.18e-2)" "unprognostic (8.43e-3)" "unprognostic (1.59e-1)" "unprognostic (5.58e-3)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-3)" "unprognostic (3.38e-1)" "unprognostic (7.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.56e-2)" "unprognostic (7.57e-3)" ATF6B "CREBL1, G13" ENSG00000213676 "Activating transcription factor 6 beta" Q99941 6 32115264-32128253 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046871 Uncertain Supported Nucleoplasm,Nucleoli NA NA 46000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA046871: AB_10963542" "unprognostic (2.93e-3)" "unprognostic (1.56e-1)" "unprognostic (5.50e-2)" "unprognostic (1.82e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (9.80e-3)" "unprognostic (1.55e-1)" "unprognostic (3.15e-1)" "unprognostic (3.68e-2)" "unprognostic (9.03e-2)" "unprognostic (3.66e-2)" "unprognostic (4.04e-3)" "unprognostic (1.75e-2)" "unprognostic (1.76e-1)" "unprognostic (3.86e-1)" "unprognostic (1.10e-2)" ATF7 ATFA ENSG00000170653 "Activating transcription factor 7" P17544 12 53507856-53626410 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003384 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 51: Oligodendrocytes - Unknown function" 8 "Nucleoplasm, Cytosol" "HPA003384: AB_1078234" "unprognostic (2.20e-2)" "unprognostic (3.10e-2)" "unprognostic (2.48e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (4.73e-2)" "unprognostic (1.54e-2)" "unprognostic (9.16e-3)" "unprognostic (3.59e-3)" "unprognostic (8.03e-2)" "unprognostic (1.76e-3)" "unprognostic (2.59e-1)" "unprognostic (3.28e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.51e-1)" "unprognostic (3.37e-1)" "unprognostic (1.17e-1)" ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Excitatory neurons: 14.7;Inhibitory neurons: 13.5;Oligodendrocyte precursor cells: 9.0;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 79: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" 11 Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.0;Inhibitory neurons: 91.5;Oligodendrocyte precursor cells: 76.4;Oligodendrocytes: 127.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 12.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 12.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.6" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 17 "HPA027550: AB_10600983" "unprognostic (2.06e-2)" "unprognostic (7.57e-3)" "unprognostic (1.82e-1)" "unprognostic (7.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (1.23e-2)" ATL2 "ARL6IP2, atlastin2" ENSG00000119787 "Atlastin GTPase 2" Q8NHH9 2 38293954-38377285 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029108, HPA075302" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Endoplasmic reticulum" "HPA029108: AB_10670557, HPA075302: AB_2732289" "unprognostic (5.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (9.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.09e-2)" "unprognostic (1.27e-3)" "unprognostic (8.22e-2)" "unprognostic (6.86e-2)" "unprognostic (4.28e-2)" "unprognostic (2.09e-1)" "unprognostic (6.33e-2)" "unprognostic (1.84e-1)" ATL3 DKFZP564J0863 ENSG00000184743 "Atlastin GTPase 3" Q6DD88 11 63624087-63671921 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 739.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065702, HPA076616" Enhanced "Endoplasmic reticulum" NA NA 58000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 1 "Endoplasmic reticulum" "HPA065702: AB_2685536, HPA076616: AB_2732318" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.32e-2)" "unprognostic (1.62e-1)" "unprognostic (6.89e-2)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (6.09e-3)" "unprognostic (3.38e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (4.52e-2)" "unprognostic (1.11e-3)" "unprognostic (7.41e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-3)" ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677273-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 91.5;Microglial cells: 206.7" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Smooth muscle cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Brain - Neuronal signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.0;intestine: 44.3" "Group enriched" "Detected in many" 4 "Distal enterocytes: 103.0;Oligodendrocyte precursor cells: 275.0;Oligodendrocytes: 390.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.2;colorectal cancer: 14.8" "Breast - Plasma cells, Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 204.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.5" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690038-112887168 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Deafness, Disease variant, Leukodystrophy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 207.7;Alveolar cells type 2: 217.0;Cone photoreceptor cells: 107.0;Glandular and luminal cells: 150.6;Oligodendrocytes: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Alveolar cells - Lung function" 1 Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 123.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 59.3;Spermatocytes: 68.7" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 1 "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 10.8;kidney: 5.2;lymphoid tissue: 14.4;placenta: 5.4;skin 1: 6.0" "Group enriched" "Detected in some" 10 "Basal respiratory cells: 170.2;Club cells: 58.6;Ionocytes: 212.8" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "testis cancer: 4.4" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 61: Plasma cells - Immunoglobulins & histones" Vesicles "HPA031798: AB_2674048, HPA049717: AB_2680858" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (4.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.33e-1)" "unprognostic (4.40e-3)" "unprognostic (3.97e-3)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (2.60e-2)" "unprognostic (1.16e-2)" "unprognostic (9.43e-3)" "prognostic unfavorable (6.51e-4)" "unprognostic (2.26e-3)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" ATP13A2 "CLN12, HSA9947, PARK9" ENSG00000159363 "ATPase cation transporting 13A2" Q9NQ11 1 16985958-17011928 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuronal ceroid lipofuscinosis, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.0" "Cell type enhanced" "Detected in many" "dendritic cells: 67.6;Horizontal cells: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.7" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037038, CAB037111, HPA050910, HPA054717" Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 7 "CAB037038: AB_1840715, CAB037111: AB_1840714, HPA050910: AB_2681269, HPA054717: AB_2682583" "unprognostic (3.81e-2)" "unprognostic (1.84e-2)" "unprognostic (5.61e-2)" "unprognostic (2.17e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.33e-7)" "unprognostic (1.04e-1)" "unprognostic (9.71e-3)" "unprognostic (4.51e-1)" "unprognostic (9.85e-3)" "unprognostic (1.85e-1)" "unprognostic (5.75e-2)" "unprognostic (3.25e-2)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (6.84e-3)" ATP13A3 AFURS1 ENSG00000133657 "ATPase 13A3" Q9H7F0 3 194402672-194498364 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 519.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029471 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Monocytes - Innate immune response" Nucleoli "Plasma membrane, Cytosol" "HPA029471: AB_10600784" "unprognostic (5.07e-2)" "unprognostic (3.53e-2)" "unprognostic (2.94e-1)" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (9.87e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.22e-1)" "unprognostic (1.65e-1)" "unprognostic (1.34e-2)" "unprognostic (3.77e-1)" ATP13A5 FLJ16025 ENSG00000187527 "ATPase 13A5" Q4VNC0 3 193274789-193378820 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 16.8;choroid plexus: 34.4;salivary gland: 11.3" "Group enriched" "Detected in some" 4 "Astrocytes: 35.9;Oligodendrocyte precursor cells: 24.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Region enriched" "Detected in all" 12 "choroid plexus: 81.5" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "Brain cancer: 1.6;breast cancer: 3.3" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA031771, HPA031772, HPA031774" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" Nucleoplasm "HPA031771: AB_2674038, HPA031772: , HPA031774: AB_2674039" "unprognostic (7.98e-2)" "unprognostic (3.01e-4)" "unprognostic (2.06e-3)" "unprognostic (2.72e-3)" "unprognostic (3.93e-1)" "unprognostic (1.67e-4)" "unprognostic (3.03e-1)" "unprognostic (2.31e-1)" "unprognostic (2.14e-2)" "unprognostic (1.73e-1)" "unprognostic (7.15e-2)" "unprognostic (1.10e-1)" "unprognostic (8.10e-2)" ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Intellectual disability, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1433.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1705.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 590.4;skeletal muscle: 850.3;tongue: 459.6" "Cell type enhanced" "Detected in some" "Astrocytes: 489.2;Cardiomyocytes: 191.0;Microglial cells: 135.1;Muller glia cells: 87.7;Oligodendrocyte precursor cells: 88.2;Schwann cells: 160.5;Skeletal myocytes: 298.6" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5;testis cancer: 1.8;thyroid cancer: 1.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 170000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease variant, Dystonia, Epilepsy, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 294.3;heart muscle: 152.5;retina: 283.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 393.6;Cone photoreceptor cells: 246.4;Horizontal cells: 317.9;Inhibitory neurons: 114.2;Late spermatids: 95.8;Rod photoreceptor cells: 245.6" "Cancer enriched" "Detected in many" 5 "glioma: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 70.2" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA 220000 "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 15 "CAB033630: AB_781528, HPA045367: AB_2679297, HPA056446: AB_2683136" "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavorable (3.44e-4)" "prognostic favorable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169310992 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Immunity, Innate immunity, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1422.9" "Cell type enhanced" "Detected in all" "Collecting duct cells: 1544.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 2100000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Proximal tubular cells - Transmembrane transport" 7 "HPA012911: AB_1845173" "unprognostic (4.20e-2)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (1.95e-1)" "unprognostic (5.34e-2)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (6.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "prognostic favorable (7.08e-7)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (1.97e-3)" "unprognostic (9.39e-2)" ATP1B2 AMOG ENSG00000129244 "ATPase Na+/K+ transporting subunit beta 2" P14415 17 7646627-7657770 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "brain: 307.4;retina: 595.7" "Group enriched" "Detected in many" 5 "Astrocytes: 196.6;Bipolar cells: 295.2;Cone photoreceptor cells: 457.1;Muller glia cells: 265.2;Rod photoreceptor cells: 205.2" "Cancer enriched" "Detected in many" 17 "glioma: 200.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 5.2" "Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010698 Supported NA NA 160000 "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA010698: AB_1845174" "unprognostic (9.39e-2)" "unprognostic (1.86e-2)" "unprognostic (3.89e-3)" "unprognostic (4.96e-3)" "unprognostic (3.90e-3)" "unprognostic (9.33e-2)" "unprognostic (4.86e-1)" "unprognostic (5.93e-2)" "unprognostic (5.43e-2)" "unprognostic (1.29e-2)" "prognostic favorable (1.05e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (4.60e-3)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (3.79e-2)" ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 967.3;Late spermatids: 993.4;monocytes: 2234.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 4 "Plasma membrane" "CAB020697: , HPA048963: AB_2680574" "unprognostic (2.31e-1)" "unprognostic (1.11e-3)" "unprognostic (2.75e-1)" "prognostic favorable (5.19e-5)" "unprognostic (2.60e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (8.11e-3)" "unprognostic (6.99e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.29e-5)" "unprognostic (5.14e-2)" "unprognostic (2.04e-1)" "unprognostic (7.19e-3)" "unprognostic (6.15e-2)" ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904466 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 85 "skeletal muscle: 7952.4;tongue: 3076.1" "Cell type enriched" "Detected in some" 112 "Skeletal myocytes: 628.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in some" 8 "thalamus: 13.1" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;cerebral cortex: 2.0;hippocampal formation: 1.7" "CAB002310, CAB032706, HPA066701" Enhanced Approved "Endoplasmic reticulum" NA NA 2800000 "Cluster 13: Non-specific - Mitochondria" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286, HPA066701: " "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "heart muscle: 970.6;skeletal muscle: 2756.0;tongue: 2661.9" "Group enriched" "Detected in all" 5 "Cardiomyocytes: 1835.3;Skeletal myocytes: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced NA NA 2500000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 "HPA062605: AB_2684805" "unprognostic (4.81e-2)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.41e-3)" "unprognostic (2.50e-1)" "unprognostic (3.98e-3)" "unprognostic (1.91e-2)" "unprognostic (6.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (9.93e-2)" ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 99.1;salivary gland: 180.1" "Cell type enhanced" "Detected in many" "B-cells: 77.7;dendritic cells: 71.0;Distal enterocytes: 113.0;Enteroendocrine cells: 73.8;Gastric mucus-secreting cells: 117.9;Intestinal goblet cells: 136.4;Plasma cells: 80.0;Serous glandular cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 134.5;lymphoma: 100.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - T-cells, Liver - T-cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 22: Eosinophils - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 75: Serous glandular cells - Salivary secretion" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709366 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 93.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 755.2;Langerhans cells: 522.1;monocytes: 818.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.5;choroid plexus: 62.8;salivary gland: 32.2;skeletal muscle: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 111.5;Bipolar cells: 80.9;Excitatory neurons: 312.4;Horizontal cells: 87.5;Inhibitory neurons: 221.2;Oligodendrocyte precursor cells: 54.7" "Cancer enhanced" "Detected in some" "liver cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.7;Neuroblastoma: 3.3" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" 1 "CAB005606: AB_2243199" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (6.84e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-1)" "unprognostic (3.62e-1)" "unprognostic (4.09e-2)" "unprognostic (4.65e-1)" "unprognostic (5.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-4)" "unprognostic (2.70e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "unprognostic (1.33e-2)" "unprognostic (8.34e-2)" "unprognostic (7.95e-3)" ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517642-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 109.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 22.9;Extravillous trophoblasts: 12.8;Horizontal cells: 22.7;Inhibitory neurons: 29.2;Skeletal myocytes: 6.8" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 503.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.9;Neuroblastoma: 9.1" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626832-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 170.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 170.1;Oligodendrocyte precursor cells: 186.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 204.8" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 154.2;Excitatory neurons: 166.6;Prostatic glandular cells: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: AB_2686169" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favorable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.2;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 44.4;Basal respiratory cells: 40.6;Ciliated cells: 46.1;Club cells: 39.4;Distal enterocytes: 42.7;Enteroendocrine cells: 42.7;Intestinal goblet cells: 66.4;Ionocytes: 63.7;Oligodendrocyte precursor cells: 55.2;Undifferentiated cells: 58.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting subunit alpha" P20648 19 35550031-35563658 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "stomach 1: 819.1" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 61.9;Late spermatids: 20.3" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039154, HPA076684" Enhanced NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 2: Neurons - Nucleosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA039154: AB_10672772, HPA076684: " "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" ATP4B ATP6B ENSG00000186009 "ATPase H+/K+ transporting subunit beta" P51164 13 113648804-113658198 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "stomach 1: 1067.1" "Cell type enriched" "Detected in some" 89 "Gastric mucus-secreting cells: 166.8" "Cancer enriched" "Detected in some" 12 "stomach cancer: 8.9" "Region enriched" "Detected in some" 6 "choroid plexus: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045400, HPA052649" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Gastric mucus-secreting cells - Digestion" 3 "Plasma membrane" "HPA045400: AB_2679314, HPA052649: AB_2681900" "unprognostic (9.92e-2)" "unprognostic (2.19e-1)" "unprognostic (2.66e-1)" "unprognostic (4.86e-1)" "unprognostic (6.43e-3)" "unprognostic (7.81e-3)" "unprognostic (1.95e-1)" "unprognostic (3.22e-1)" "unprognostic (6.50e-2)" "unprognostic (6.65e-4)" "unprognostic (2.25e-1)" "unprognostic (2.78e-1)" "unprognostic (3.78e-2)" ATP5MC2 ATP5G2 ENSG00000135390 "ATP synthase membrane subunit c locus 2" Q06055 12 53632726-53677408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051469 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 7: Non-specific - Ribosome" "Cluster 38: Non-specific - Transcription" "Cluster 64: Non-specific - Ribosome" "HPA051469: AB_2681496" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (3.01e-1)" "unprognostic (3.37e-3)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (2.97e-3)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (3.78e-2)" "unprognostic (5.71e-2)" "unprognostic (3.32e-3)" "unprognostic (3.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.42e-1)" "unprognostic (7.09e-2)" ATP5MF "ATP5J2, ATP5JL" ENSG00000241468 "ATP synthase membrane subunit f" P56134 7 99448475-99466186 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1487.5;Proximal tubular cells: 1727.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067267, HPA070412" Approved Supported "Nuclear membrane,Mitochondria" NA NA 60000 "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear membrane" "HPA067267: AB_2685815, HPA070412: AB_2686266" "unprognostic (2.43e-2)" "unprognostic (1.42e-1)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (4.55e-3)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (6.19e-2)" "unprognostic (2.31e-3)" "unprognostic (2.58e-1)" "unprognostic (3.65e-2)" "unprognostic (6.88e-3)" "unprognostic (9.24e-2)" "unprognostic (4.90e-2)" "unprognostic (2.52e-1)" "unprognostic (5.78e-2)" ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401346-118433278 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2732.3;Proximal tubular cells: 2459.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" HPA044629 Approved Supported Mitochondria NA NA 44000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 39: Non-specific - Basic cellular processes" 2 Mitochondria "HPA044629: AB_2679028" "unprognostic (1.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (7.41e-2)" "prognostic favorable (4.09e-5)" "unprognostic (6.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.05e-2)" ATP5MJ "6.8PL, ATP5MPL, C14orf2, MLQ, MP68" ENSG00000156411 "ATP synthase membrane subunit j" P56378 14 103912288-103928269 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3403.4;Distal tubular cells: 1871.7;Proximal tubular cells: 2004.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058978, HPA060520" Approved Supported "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoli fibrillar center" "HPA058978: AB_2683867, HPA060520: AB_2684302" "unprognostic (1.37e-1)" "unprognostic (1.42e-3)" "unprognostic (1.55e-1)" "unprognostic (2.30e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-2)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "prognostic favorable (6.80e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (1.34e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (1.57e-1)" "unprognostic (4.14e-2)" ATP5MK "AGP, ATP5MD, bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit k" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4779.1;Hepatocytes: 2184.1;Proximal tubular cells: 2178.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.3;tongue: 126.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 768.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" Transport NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 12 Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Approved NA NA 700000 "Cluster 29: Non-specific - Unknown function" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 1 "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 739.6" "Cell type enhanced" "Detected in all" "Hofbauer cells: 658.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 11 "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 420.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Photoreceptor cells - Visual perception" 1 "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" ATP6V0A2 "a2, a2V, ATP6a2, ATP6N1D, J6B7, RTF, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 61.4;salivary gland: 76.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 19.4;Cytotrophoblasts: 13.4;Distal tubular cells: 18.4;Ionocytes: 11.4;Melanocytes: 8.6;Salivary duct cells: 24.4;Serous glandular cells: 13.1" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Region enriched" "Detected in some" 5 "choroid plexus: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 10.7;Gastric cancer: 9.7;skin cancer: 8.2" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 1 Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 851.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2279.8" "Group enriched" "Detected in all" 4 "dendritic cells: 771.1;granulocytes: 2279.8;monocytes: 1048.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" 19 Cytosol "HPA044281: " "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (5.69e-2)" "unprognostic (5.31e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (7.23e-2)" "prognostic favorable (3.24e-4)" "unprognostic (6.13e-2)" "prognostic favorable (3.62e-6)" "unprognostic (5.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (8.87e-4)" ATP6V0C "ATP6C, ATP6L, ATPL, VATL, Vma3" ENSG00000185883 "ATPase H+ transporting V0 subunit c" P27449 16 2513952-2520218 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 111.3;Basal squamous epithelial cells: 334.0;Gastric mucus-secreting cells: 126.2;Inhibitory neurons: 102.6;Macrophages: 117.9;Plasma cells: 160.3;Squamous epithelial cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065100 Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 47 Vesicles "HPA065100: AB_2685421" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.96e-2)" "unprognostic (7.67e-2)" "unprognostic (2.31e-1)" "unprognostic (4.20e-3)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "prognostic favorable (1.07e-6)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.85e-1)" "unprognostic (5.04e-2)" ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910690-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Non-specific - Transcription" 2 "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.6;Early spermatids: 43.9;Late spermatids: 84.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Golgi apparatus" "HPA009137: AB_2668214, HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657121 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 38.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 286.0;Inhibitory neurons: 245.2;Oligodendrocytes: 1133.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 17.2" "Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 51: Oligodendrocytes - Unknown function" 2 Cytosol Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 19.7;pituitary gland: 14.8;retina: 14.3" "Group enriched" "Detected in many" 6 "Excitatory neurons: 501.3;Inhibitory neurons: 697.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 5.2" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 73.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 267.3;Enteroendocrine cells: 106.9;Gastric mucus-secreting cells: 116.1;Intestinal goblet cells: 161.6;Paneth cells: 111.3;Undifferentiated cells: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 25.4;Excitatory neurons: 27.6;Inhibitory neurons: 30.5;Prostatic glandular cells: 25.8;T-cells: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 2.7;T-cells: 4.9" "Cancer enhanced" "Detected in all" "Myeloma: 105.7" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 77.2" "Cell type enriched" "Detected in many" 7 "Microglial cells: 237.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.3;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.3;NK-cells: 11.0" "Cancer enriched" "Detected in some" 6 "Leukemia: 14.8" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768390 "Enzymes, Predicted membrane proteins, Transporters" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.4;Inhibitory neurons: 83.4;Oligodendrocytes: 84.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB020699: , HPA035630: AB_10669526" "unprognostic (5.19e-2)" "unprognostic (5.28e-2)" "unprognostic (3.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-2)" "unprognostic (4.79e-2)" "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "prognostic favorable (5.67e-5)" "unprognostic (5.82e-2)" "unprognostic (5.81e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 86.4;Excitatory neurons: 121.8;Inhibitory neurons: 110.1;Oligodendrocyte precursor cells: 107.5;Oligodendrocytes: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" ATPSCKMT "FAM173B, JS-2" ENSG00000150756 "ATP synthase c subunit lysine N-methyltransferase" Q6P4H8 5 10225507-10249897 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074513 Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA074513: AB_2686698" "prognostic unfavorable (1.32e-6)" "unprognostic (8.87e-3)" "unprognostic (1.23e-3)" "unprognostic (1.20e-1)" "unprognostic (9.24e-2)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-2)" "unprognostic (6.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-1)" "unprognostic (9.06e-2)" "unprognostic (5.61e-2)" "unprognostic (1.03e-1)" ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" 6 Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212041-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "HPA051353: AB_2681451" "unprognostic (4.58e-2)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.59e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.73e-2)" "unprognostic (5.35e-3)" "unprognostic (2.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-1)" ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 98.2;Inhibitory neurons: 96.8;Oligodendrocyte precursor cells: 84.0;Oligodendrocytes: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" Receptor NA NA 27000000000 "Cluster 22: Eosinophils - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 62: Hepatocytes - Metabolism" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2065.6;Inhibitory neurons: 1418.2;Oligodendrocyte precursor cells: 1366.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106621 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Non-specific - Transcription" 74 "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: AB_2686124" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" AUP1 ENSG00000115307 "AUP1 lipid droplet regulating VLDL assembly factor" Q9Y679 2 74526645-74529760 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007674 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Plasma cells - Protein processing" 2 "Nucleoplasm, Vesicles" "HPA007674: AB_1078251" "unprognostic (1.09e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-2)" "unprognostic (2.11e-2)" "unprognostic (5.97e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.00e-1)" "unprognostic (2.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (2.97e-9)" "unprognostic (9.68e-2)" "unprognostic (1.59e-1)" "unprognostic (3.35e-1)" "unprognostic (3.96e-2)" AVL9 KIAA0241 ENSG00000105778 "AVL9 cell migration associated" Q8NBF6 7 32495426-32588726 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 90.7;Inhibitory neurons: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050957 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" "HPA050957: AB_2681289" "unprognostic (2.33e-2)" "unprognostic (8.75e-3)" "unprognostic (3.45e-2)" "unprognostic (1.94e-1)" "unprognostic (8.07e-2)" "unprognostic (5.72e-3)" "unprognostic (5.14e-3)" "unprognostic (4.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (4.21e-2)" "unprognostic (9.03e-2)" "unprognostic (1.68e-2)" "unprognostic (3.68e-2)" "unprognostic (9.22e-2)" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" AVPR1B "AVPR3, V1bR, VPR3" ENSG00000198049 "Arginine vasopressin receptor 1B" P47901 1 206106936-206117699 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "pituitary gland: 6.6" "Group enriched" "Detected in some" 21 "Enteroendocrine cells: 10.6;Glandular and luminal cells: 2.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA075404 Enhanced NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA075404: AB_2732291" "unprognostic (4.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.82e-1)" "unprognostic (2.82e-1)" "unprognostic (2.87e-1)" "unprognostic (1.08e-2)" "unprognostic (3.33e-1)" "unprognostic (2.96e-2)" "unprognostic (6.23e-2)" "unprognostic (7.65e-2)" "unprognostic (1.86e-1)" "unprognostic (6.66e-3)" AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240659 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" HPA063412 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 27: Breast cancer - Unknown function" "HPA063412: AB_2685009" "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.96e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 10.9" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 6.9" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA062748 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA062748: AB_2684862" "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 125.3;Kupffer cells: 138.5;Langerhans cells: 188.8;Sertoli cells: 136.0;Smooth muscle cells: 124.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.3;plasmacytoid DC: 25.8" "Group enriched" "Detected in many" 12 "dendritic cells: 25.8;NK-cells: 11.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 812.7" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" 3 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193178730-193186613 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;gallbladder: 14.6;heart muscle: 20.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 41.2;Cardiomyocytes: 43.5;Excitatory neurons: 26.6;Inhibitory neurons: 27.0;Leydig cells: 29.4;Peritubular cells: 19.5" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 8.4" "Lineage enriched" "Detected in single" 53 "T-cells: 8.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.5" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "HPA078659: AB_2686887" "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" B3GAT2 GlcAT-S ENSG00000112309 "Beta-1,3-glucuronyltransferase 2" Q9NPZ5 6 70856679-70957060 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 15.8;retina: 17.8" "Cell type enhanced" "Detected in many" "Horizontal cells: 98.2;Oocytes: 52.2" "Group enriched" "Detected in some" 20 "glioma: 4.7;testis cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012059 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA012059: AB_2061050" "unprognostic (7.10e-3)" "unprognostic (7.81e-2)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.96e-2)" "unprognostic (4.88e-2)" "unprognostic (4.22e-2)" "unprognostic (9.16e-4)" "unprognostic (8.09e-2)" "unprognostic (7.43e-3)" "unprognostic (6.88e-7)" "unprognostic (2.72e-2)" "unprognostic (3.35e-2)" "unprognostic (2.53e-2)" "unprognostic (3.45e-3)" B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196115-62224731 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles NA NA 99000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.8;Distal enterocytes: 29.9;Enteroendocrine cells: 6.6;Glandular and luminal cells: 6.2;Intestinal goblet cells: 25.3;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 2 "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Langerhans cells: 357.0;monocytes: 409.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 215.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 97000000 "Cluster 30: Non-specific - DNA binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" "HPA010806: AB_1078255, HPA010807: AB_1078254" "unprognostic (7.57e-2)" "unprognostic (1.24e-2)" "unprognostic (2.09e-1)" "prognostic favorable (6.85e-7)" "unprognostic (1.83e-2)" "unprognostic (9.94e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-3)" "unprognostic (2.78e-1)" "unprognostic (7.93e-3)" "unprognostic (4.98e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.46e-2)" B4GALT2 beta4Gal-T2 ENSG00000117411 "Beta-1,4-galactosyltransferase 2" O60909 1 43978943-43991170 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007620, HPA047739" Supported Supported "Golgi apparatus,Vesicles" NA NA 3100000 "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Non-specific - DNA binding" "Golgi apparatus, Vesicles" "HPA007620: AB_2667879, HPA047739: AB_2680141" "unprognostic (1.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-1)" "unprognostic (7.59e-2)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (4.23e-3)" "unprognostic (7.58e-2)" "prognostic unfavorable (3.62e-5)" "unprognostic (6.54e-2)" "unprognostic (1.52e-1)" "unprognostic (7.66e-2)" "unprognostic (3.12e-3)" BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285232-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 133.1;pancreas: 250.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 152.9;Late spermatids: 353.3;Oligodendrocytes: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" 10 "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.0" "Cell type enhanced" "Detected in many" "Melanocytes: 261.1;Mucus glandular cells: 248.8;Syncytiotrophoblasts: 521.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cancer enhanced" "Detected in many" "skin cancer: 55.9" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 14 "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 67.4;Proximal enterocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 61: Plasma cells - Immunoglobulins & histones" 18 "CAB005029: AB_562051" "unprognostic (3.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (5.67e-2)" "unprognostic (6.58e-3)" "prognostic unfavorable (4.52e-4)" "prognostic unfavorable (5.64e-4)" "unprognostic (2.36e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (6.07e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 165.2;Breast myoepithelial cells: 165.8;Granulosa cells: 74.0;Ovarian stromal cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 329.6" "Lung - Fibroblast_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 30: White matter - Myelination" "Cluster 32: Non-specific - Cell proliferation" "Cluster 50: Connective tissue cells - ECM organization" 1 Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: AB_2668371, HPA010866: AB_10601686" "unprognostic (7.02e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-2)" "unprognostic (3.17e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (9.42e-6)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-3)" "unprognostic (9.29e-2)" "prognostic favorable (5.25e-4)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (2.38e-2)" "unprognostic (2.10e-2)" BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 308.1" "Cell type enhanced" "Detected in many" "Adipocytes: 358.1;Basal respiratory cells: 432.6;Collecting duct cells: 488.2;Cytotrophoblasts: 688.0;Secretory cells: 548.9;Syncytiotrophoblasts: 406.4" "Cancer enhanced" "Detected in all" "ovarian cancer: 493.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 18000000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" 6 "Nucleoli fibrillar center" "HPA005654: AB_2667378" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (2.61e-3)" "unprognostic (1.41e-1)" "prognostic favorable (5.94e-6)" "unprognostic (1.83e-2)" "unprognostic (5.74e-2)" "unprognostic (2.14e-2)" "unprognostic (9.97e-3)" BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.0;Excitatory neurons: 78.4;Inhibitory neurons: 68.3;Oligodendrocyte precursor cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 560.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 12 "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Schwann cells: 119.6;T-cells: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.6" "Cancer enhanced" "Detected in all" "lymphoma: 53.5;Myeloma: 68.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000003, CAB080071, CAB080083" Enhanced Enhanced Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 25 Mitochondria "CAB000003: AB_2064429, CAB080071: , CAB080083: " "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 22 Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" BCL2L10 "BCL-B, Boo, Diva" ENSG00000137875 "BCL2 like 10" Q9HD36 15 52109263-52112775 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 9.3;skin 1: 6.7" "Cell type enriched" "Detected in many" 17 "Oocytes: 211.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA042222 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Oocytes - Unknown function" 8 "HPA042222: AB_10794271" "unprognostic (5.33e-4)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (3.22e-4)" "unprognostic (1.19e-2)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "unprognostic (4.80e-3)" "unprognostic (8.86e-2)" "unprognostic (3.47e-2)" "unprognostic (9.52e-2)" "unprognostic (3.83e-1)" "unprognostic (2.18e-9)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.92e-1)" "unprognostic (3.20e-2)" BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.5" "Cell type enhanced" "Detected in all" "Bipolar cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 33: Non-specific - ATP binding" "Cluster 3: Non-specific - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 25: Bipolar cells - Visual perception" 42 Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Smooth muscle cells - Muscle contraction" 45 Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037700, HPA037701" Supported NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" "HPA037700: AB_10794619, HPA037701: AB_10805235" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (6.28e-2)" "unprognostic (4.99e-2)" "unprognostic (6.44e-2)" "unprognostic (4.31e-1)" "unprognostic (4.25e-2)" "unprognostic (2.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.83e-2)" "unprognostic (1.21e-2)" "unprognostic (6.02e-2)" "unprognostic (3.47e-3)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" "unprognostic (8.38e-2)" "prognostic favorable (3.31e-4)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 22.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.0;Basal squamous epithelial cells: 29.9;Mesothelial cells: 25.2;Squamous epithelial cells: 20.4;Suprabasal keratinocytes: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 16.0;Endothelial cells: 16.7;Fibroblasts: 17.0;Ionocytes: 16.2;Langerhans cells: 19.0;Squamous epithelial cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.2" "Kidney - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.5;Bipolar cells: 9.6;Cardiomyocytes: 11.4;Excitatory neurons: 21.5;Granulosa cells: 20.8;Oocytes: 11.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 27.6" "Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB009564 Enhanced "Secreted to blood" "Growth factor" NA Yes 16000000 24000 "Cluster 30: Heart muscle - Heart development" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 15: Non-specific - Mixed function" 1 "CAB009564: AB_2064213" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" BEAN1 SCA31 ENSG00000166546 "Brain expressed associated with NEDD4 1" Q3B7T3 16 66427295-66493529 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.9;Early spermatids: 10.1;Excitatory neurons: 9.6;Extravillous trophoblasts: 12.6;Inhibitory neurons: 7.4;Late spermatids: 13.9;Melanocytes: 6.9;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 5.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.8" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053851 Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA053851: AB_2682280" "unprognostic (1.92e-1)" "unprognostic (5.79e-4)" "unprognostic (3.83e-2)" "unprognostic (3.38e-3)" "unprognostic (1.01e-1)" "unprognostic (4.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.13e-1)" "unprognostic (4.89e-1)" "unprognostic (1.59e-1)" "unprognostic (2.13e-3)" "unprognostic (4.18e-2)" "unprognostic (3.38e-2)" "unprognostic (1.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-2)" BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;brain: 32.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.3;Kupffer cells: 32.2;monocytes: 51.4;Oligodendrocytes: 40.1" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.8" "Cancer enriched" "Detected in many" 4 "skin cancer: 18.3" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 74: Neutrophils - Degranulation" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" BEST2 "FLJ20132, VMD2L1" ENSG00000039987 "Bestrophin 2" Q8NFU1 19 12751702-12758458 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 44.0;skin 1: 16.8" "Cell type enriched" "Detected in some" 20 "Intestinal goblet cells: 126.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" HPA046229 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 16: Intestinal goblet cells - Mucin production" 14 "HPA046229: AB_10966140" "unprognostic (3.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.54e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-2)" "unprognostic (4.02e-3)" "unprognostic (2.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.18e-1)" "unprognostic (2.43e-1)" "unprognostic (3.46e-3)" "unprognostic (9.18e-6)" "unprognostic (3.45e-2)" "unprognostic (6.95e-2)" "unprognostic (2.90e-1)" "unprognostic (1.64e-5)" BEST3 "MGC13168, MGC40411, VMD2L3" ENSG00000127325 "Bestrophin 3" Q8N1M1 12 69643360-69699476 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 66.7;tongue: 53.5" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 66.0;Skeletal myocytes: 137.6" "Cancer enriched" "Detected in single" 9 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 34.8" "Pancreas - Beta cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054582 Approved NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA054582: AB_2682530" "unprognostic (1.53e-1)" "unprognostic (7.00e-2)" "unprognostic (9.83e-2)" "unprognostic (1.67e-2)" "unprognostic (5.15e-3)" "unprognostic (2.26e-3)" "unprognostic (7.30e-7)" "unprognostic (1.81e-1)" "unprognostic (1.74e-2)" "unprognostic (5.36e-2)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (4.82e-2)" "unprognostic (4.47e-2)" "unprognostic (3.03e-1)" BEST4 VMD2L2 ENSG00000142959 "Bestrophin 4" Q8NFU0 1 44783585-44788170 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 14.2;intestine: 26.6" "Cell type enriched" "Detected in some" 32 "Paneth cells: 1407.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "choroid plexus: 37.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" HPA058564 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA058564: AB_2683759" "unprognostic (5.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-2)" "unprognostic (6.51e-3)" "unprognostic (1.09e-1)" "unprognostic (8.39e-2)" "unprognostic (1.45e-3)" "unprognostic (1.04e-1)" "unprognostic (8.97e-2)" "unprognostic (5.72e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-5)" "unprognostic (1.43e-1)" "unprognostic (3.72e-1)" "unprognostic (1.28e-1)" "unprognostic (4.13e-3)" BET1L "GOLIM3, GS15" ENSG00000177951 "Bet1 golgi vesicular membrane trafficking protein like" Q9NYM9 11 167784-207399 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039819 Approved Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 6: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 63: Late spermatids - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA039819: AB_10673020" "unprognostic (1.68e-1)" "unprognostic (2.07e-1)" "unprognostic (2.14e-3)" "unprognostic (2.56e-3)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.82e-1)" "unprognostic (1.52e-1)" "unprognostic (3.08e-2)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (9.10e-2)" "unprognostic (1.69e-1)" "unprognostic (3.75e-2)" "unprognostic (8.49e-2)" BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 324.9;Club cells: 133.3;Ionocytes: 370.4;Oocytes: 288.2;Paneth cells: 124.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 73.0;plasmacytoid DC: 58.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 79 "HPA051360: AB_2681453" "unprognostic (1.18e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.86e-3)" "unprognostic (3.27e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.45e-5)" "unprognostic (1.38e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (3.04e-1)" BLTP1 "FLJ21404, FSA, KIAA1109, KIAA1371, Tweek" ENSG00000138688 "Bridge-like lipid transfer protein family member 1" Q2LD37 4 122152331-122364167 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 232.5;Inhibitory neurons: 235.7;Oligodendrocytes: 223.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038076 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 3: Non-specific - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Centrosome" "HPA038076: AB_10670652" "unprognostic (2.53e-1)" "unprognostic (2.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (6.62e-2)" "unprognostic (7.61e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.33e-8)" "unprognostic (2.04e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (2.29e-2)" BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 135.3;Inhibitory neurons: 76.7;Oligodendrocyte precursor cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 3 Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 174.0;Excitatory neurons: 195.3;Inhibitory neurons: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" BMT2 "C7orf60, DKFZp762M126, FLJ31818, SAMTOR" ENSG00000164603 "Base methyltransferase of 25S rRNA 2 homolog" Q1RMZ1 7 112819147-112939875 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.6;Inhibitory neurons: 58.0;Microglial cells: 46.5;Oligodendrocyte precursor cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044405, HPA050733" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 16: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA044405: AB_10959783, HPA050733: AB_2681223" "unprognostic (5.26e-2)" "unprognostic (3.95e-2)" "unprognostic (2.86e-1)" "unprognostic (2.39e-1)" "unprognostic (2.48e-1)" "unprognostic (1.11e-1)" "unprognostic (7.61e-5)" "unprognostic (1.50e-3)" "unprognostic (1.61e-2)" "unprognostic (9.82e-3)" "unprognostic (1.68e-1)" "unprognostic (2.30e-1)" "unprognostic (1.04e-1)" "unprognostic (6.94e-2)" "unprognostic (1.13e-1)" "unprognostic (8.22e-2)" "unprognostic (9.10e-2)" BNIP1 "Nip1, SEC20" ENSG00000113734 "BCL2 interacting protein 1" Q12981 5 173144442-173164387 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008009, HPA008149" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 44: Oocytes - Unknown function" 14 "Endoplasmic reticulum" "HPA008009: AB_1078291, HPA008149: AB_2667993" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (5.89e-2)" "unprognostic (3.08e-1)" "unprognostic (2.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.71e-2)" "unprognostic (1.50e-1)" "unprognostic (7.38e-2)" "unprognostic (2.70e-2)" "unprognostic (1.84e-2)" "unprognostic (2.28e-1)" "unprognostic (4.40e-3)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" "unprognostic (5.61e-2)" "unprognostic (3.07e-2)" BNIP3 "HABON, Nip3" ENSG00000176171 "BCL2 interacting protein 3" Q12983 10 131967684-131981967 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 439.6" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 544.8;Hepatocytes: 459.6;Proximal tubular cells: 581.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003015, CAB011676" Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 49 "CAB011676: , HPA003015: AB_1078290" "unprognostic (1.01e-3)" "unprognostic (1.42e-3)" "unprognostic (1.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.58e-2)" "unprognostic (1.62e-3)" "unprognostic (6.57e-3)" "unprognostic (1.12e-1)" "unprognostic (2.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (4.55e-4)" "unprognostic (2.37e-3)" "unprognostic (1.04e-1)" "unprognostic (3.29e-2)" "unprognostic (2.98e-1)" BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 14 Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 124.9;skin 1: 176.2;vagina: 67.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 19.9;Club cells: 16.4;Squamous epithelial cells: 49.5;Suprabasal keratinocytes: 83.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Low region specificity" "Detected in many" HPA019946 Uncertain Cytosol NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" BOC "Boi, CDON2" ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.1;Basal squamous epithelial cells: 58.7;Fibroblasts: 59.9;Leydig cells: 82.7;Peritubular cells: 44.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA No 7900000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" BRI3 ENSG00000164713 "Brain protein I3" O95415 7 98252379-98310441 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 43.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042215 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 5 "HPA042215: AB_10794790" "unprognostic (1.51e-2)" "unprognostic (5.03e-2)" "unprognostic (7.08e-3)" "unprognostic (3.48e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.35e-4)" "unprognostic (2.04e-2)" "unprognostic (1.88e-2)" "unprognostic (3.93e-1)" "unprognostic (4.68e-1)" "unprognostic (1.66e-1)" "unprognostic (6.60e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.71e-1)" BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.2" "Cell type enhanced" "Detected in many" "Late spermatids: 164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 3 "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" BRICD5 "C16orf79, MGC21830" ENSG00000182685 "BRICHOS domain containing 5" Q6PL45 16 2209253-2210905 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 96.1" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.0" HPA063522 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "Actin filaments" Nucleoplasm "HPA063522: AB_2685029" "prognostic favorable (9.74e-4)" "unprognostic (7.12e-3)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (1.93e-3)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (4.34e-3)" "unprognostic (7.56e-2)" "prognostic favorable (7.01e-4)" "unprognostic (9.84e-3)" "unprognostic (2.65e-2)" "unprognostic (9.79e-2)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "prognostic favorable (8.06e-5)" BRSK1 "KIAA1811, SAD-B" ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 197.5;pituitary gland: 51.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Excitatory neurons: 29.1;Horizontal cells: 35.3;Inhibitory neurons: 26.4;Oligodendrocyte precursor cells: 16.0;Oligodendrocytes: 27.3;Plasma cells: 14.8;Proximal enterocytes: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 43.9" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" BRSK2 "C11orf7, PEN11B, SAD-A, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 108.5;pancreas: 101.2" "Cell type enhanced" "Detected in some" "Astrocytes: 21.7;Bipolar cells: 80.6;Excitatory neurons: 34.3;Horizontal cells: 54.8;Inhibitory neurons: 22.5;Muller glia cells: 20.8;Oligodendrocyte precursor cells: 18.9;Oligodendrocytes: 19.2;Rod photoreceptor cells: 30.5" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.3" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62689289-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 281.3;pituitary gland: 230.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.6;Gastric mucus-secreting cells: 20.0;Late spermatids: 39.0;Plasma cells: 56.7;Spermatocytes: 24.0;Squamous epithelial cells: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Plasma cells - Protein processing" 3 "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favorable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1413.1;Distal enterocytes: 1719.0;Syncytiotrophoblasts: 1570.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 7: Non-specific - Innate immune response" "Cluster 30: Heart muscle - Heart development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 3 Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" BSND "BART, DFNB73" ENSG00000162399 "Barttin CLCNK type accessory subunit beta" Q8WZ55 1 54998933-55017172 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "kidney: 9.2" "Group enriched" "Detected in some" 8 "Collecting duct cells: 9.7;Distal tubular cells: 9.2;Ionocytes: 16.9;Salivary duct cells: 6.2" "Cancer enriched" "Detected in some" 7 "renal cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053836, HPA060617" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" 25 "HPA053836: AB_2682277, HPA060617: AB_2732651" "unprognostic (3.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.97e-3)" "unprognostic (3.35e-1)" "unprognostic (8.97e-3)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.93e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-2)" "unprognostic (1.68e-2)" "unprognostic (1.57e-1)" BST2 "BST-2, CD317, HM1.24, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 672.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1191.1;Ovarian stromal cells: 1315.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 6: Ovarian stromal cells - Transcription" 2 "Golgi apparatus, Vesicles" "HPA017060: AB_1845467, HPA073472: " "prognostic favorable (6.69e-4)" "unprognostic (1.75e-1)" "unprognostic (8.42e-3)" "unprognostic (8.93e-3)" "unprognostic (4.87e-2)" "unprognostic (2.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "unprognostic (6.46e-2)" "unprognostic (6.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.56e-9)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" BTLA "BTLA1, CD272" ENSG00000186265 "B and T lymphocyte associated" Q7Z6A9 3 112463966-112499472 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 27.8" "Cell type enhanced" "Detected in some" "B-cells: 63.4;dendritic cells: 18.2;Plasma cells: 21.0;Schwann cells: 20.4;T-cells: 9.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "memory B-cell: 65.3;naive B-cell: 96.8;plasmacytoid DC: 24.9" "Group enriched" "Detected in many" 4 "B-cells: 96.8;dendritic cells: 24.9" "Cancer enhanced" "Detected in some" "lymphoma: 3.6;Myeloma: 13.3" "Breast - Plasma cells" "Not detected" "Not detected" "HPA047211, HPA062029" Enhanced NA NA "Cluster 34: B-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "HPA047211: AB_2679983, HPA062029: AB_2684665" "unprognostic (1.13e-3)" "unprognostic (2.13e-3)" "unprognostic (5.79e-4)" "unprognostic (1.01e-4)" "unprognostic (7.08e-2)" "unprognostic (7.74e-6)" "unprognostic (6.20e-3)" "unprognostic (7.59e-3)" "unprognostic (5.98e-2)" "unprognostic (1.53e-5)" "unprognostic (2.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.57e-5)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" BTN1A1 "BT, BTN, BTN1" ENSG00000124557 "Butyrophilin subfamily 1 member A1" Q13410 6 26500303-26510425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "breast: 31.0" "Cell type enriched" "Detected in some" 52 "Breast glandular cells: 108.0" "Cancer enhanced" "Detected in single" "breast cancer: 0.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011126, CAB037340" Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 73: Breast - Lactation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 1 "CAB037340: , HPA011126: AB_1845491" "unprognostic (4.07e-2)" "unprognostic (1.40e-1)" "unprognostic (1.90e-2)" "unprognostic (1.67e-1)" "unprognostic (2.32e-1)" "unprognostic (1.77e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" "unprognostic (3.24e-3)" "unprognostic (2.85e-1)" "unprognostic (1.88e-1)" "unprognostic (5.35e-10)" "unprognostic (4.62e-2)" "unprognostic (1.38e-1)" "unprognostic (4.14e-2)" "unprognostic (5.31e-4)" BTN2A1 "BT2.1, BTF1, BTN2.1" ENSG00000112763 "Butyrophilin subfamily 2 member A1" Q7KYR7 6 26457904-26476621 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA019208 Approved Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "HPA019208: AB_1845492" "unprognostic (1.86e-1)" "unprognostic (3.48e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-1)" "unprognostic (2.29e-1)" "unprognostic (6.17e-2)" "unprognostic (5.74e-3)" "unprognostic (1.22e-2)" "unprognostic (1.03e-1)" "unprognostic (3.26e-2)" "unprognostic (6.90e-3)" "unprognostic (5.14e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.97e-1)" "unprognostic (4.89e-2)" "unprognostic (7.92e-2)" "prognostic favorable (4.52e-5)" BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 63.3;Langerhans cells: 29.4;Plasma cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 76.2" "Lung - NK-cells (Lung), Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Granulocytes - Unknown function" 33 Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 71.1;Plasma cells: 34.4;T-cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 19: NK-cells - Adaptive immune response" 3 Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" BTN3A2 BTN3.2 ENSG00000186470 "Butyrophilin subfamily 3 member A2" P78410 6 26365159-26378320 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 181.0;Plasma cells: 83.3;T-cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells" CAB019392 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 19: NK-cells - Adaptive immune response" 3 "CAB019392: " "unprognostic (3.77e-2)" "unprognostic (1.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.86e-2)" "unprognostic (3.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (3.89e-1)" "unprognostic (4.04e-2)" "unprognostic (1.30e-3)" "unprognostic (1.12e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (5.13e-2)" "unprognostic (4.45e-2)" "unprognostic (4.42e-2)" "unprognostic (1.48e-3)" BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 30.2;Plasma cells: 22.8;T-cells: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" "HPA007904, HPA011871" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA007904: AB_1078307, HPA011871: AB_1845496" "unprognostic (1.18e-2)" "unprognostic (6.54e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (5.13e-3)" "unprognostic (8.08e-2)" "unprognostic (7.88e-2)" "prognostic favorable (1.80e-4)" "unprognostic (4.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (3.49e-2)" "unprognostic (2.14e-2)" "unprognostic (5.26e-2)" "unprognostic (4.54e-3)" BTNL8 "BTN9.2, FLJ21458" ENSG00000113303 "Butyrophilin like 8" Q6UX41 5 180899077-180950906 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 115.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.9;Intestinal goblet cells: 36.0;Paneth cells: 38.9;Proximal enterocytes: 189.8" "Group enriched" "Detected in some" 12 "colorectal cancer: 2.6;liver cancer: 1.5;pancreatic cancer: 2.8;stomach cancer: 3.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "neutrophil: 234.3" "Lineage enriched" "Detected in many" 221 "granulocytes: 234.3" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.8;Esophageal cancer: 1.8;Gastric cancer: 3.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA039738 Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA039738: AB_2676656" "unprognostic (4.31e-1)" "unprognostic (6.85e-6)" "unprognostic (6.99e-2)" "unprognostic (1.48e-1)" "unprognostic (6.33e-2)" "unprognostic (1.91e-1)" "unprognostic (6.27e-3)" "unprognostic (6.07e-2)" "unprognostic (3.08e-3)" "unprognostic (3.28e-1)" "unprognostic (1.67e-1)" "unprognostic (9.02e-2)" "unprognostic (4.96e-3)" "unprognostic (2.93e-1)" "unprognostic (1.42e-1)" "unprognostic (4.43e-1)" "unprognostic (1.17e-2)" BTNL9 "BTN8, FLJ32535" ENSG00000165810 "Butyrophilin like 9" Q6UXG8 5 181040225-181061521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 242.8;breast: 193.5" "Cell type enriched" "Detected in many" 6 "Adipocytes: 794.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.6" "Adipose visceral - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043429 Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nuclear membrane" Vesicles "HPA043429: AB_10961264" "unprognostic (2.69e-1)" "unprognostic (1.44e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.07e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.55e-9)" "unprognostic (2.15e-2)" "unprognostic (8.51e-2)" "unprognostic (1.78e-1)" "unprognostic (1.93e-3)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.71e-2)" "unprognostic (3.43e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-2)" BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 26.8;skeletal muscle: 42.3;tongue: 28.1" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 41.7;Early spermatids: 40.9;Late spermatids: 57.0;Oligodendrocytes: 16.6;Skeletal myocytes: 20.5;Spermatocytes: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 16.5" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Late spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 103.7;Plasma cells: 78.3;Proximal enterocytes: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 7 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" C11orf87 "LOC399947, LOH11CR1A, NEURIM1" ENSG00000185742 "Chromosome 11 open reading frame 87" Q6NUJ2 11 109422190-109429167 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 18.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 50.7;Horizontal cells: 25.8;Inhibitory neurons: 31.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "Rhabdoid: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034656 Approved NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 18 "HPA034656: AB_10600788" "unprognostic (5.42e-2)" "unprognostic (2.09e-1)" "unprognostic (2.28e-1)" "unprognostic (8.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.85e-1)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.62e-1)" "unprognostic (2.44e-2)" "unprognostic (2.45e-1)" "unprognostic (5.28e-5)" "unprognostic (8.38e-2)" "unprognostic (9.65e-2)" "unprognostic (2.72e-6)" C16orf54 FLJ35681 ENSG00000185905 "Chromosome 16 open reading frame 54" Q6UWD8 16 29742463-29745990 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 40.7;lymphoid tissue: 20.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;dendritic cells: 38.3;granulocytes: 25.3;monocytes: 36.9;NK-cells: 72.5;Plasma cells: 39.5;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 15.6;Myeloma: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060546 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 "HPA060546: AB_2684317" "unprognostic (2.09e-3)" "unprognostic (1.58e-3)" "unprognostic (1.30e-2)" "unprognostic (1.92e-4)" "unprognostic (2.08e-1)" "unprognostic (1.54e-2)" "unprognostic (1.36e-3)" "unprognostic (2.90e-2)" "unprognostic (2.44e-3)" "unprognostic (1.06e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (9.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-1)" C17orf80 "FLJ20721, HLC-8, MIG3, SPEP1" ENSG00000141219 "Chromosome 17 open reading frame 80" Q9BSJ5 17 73232233-73248959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 187.3;Late spermatids: 110.3;Spermatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010974, HPA012896, HPA073479" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 Mitochondria Cytosol "HPA010974: , HPA012896: AB_1850766, HPA073479: " "unprognostic (9.22e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.43e-4)" "unprognostic (5.55e-3)" "unprognostic (8.58e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (9.02e-6)" "unprognostic (1.08e-1)" "unprognostic (1.00e-3)" "unprognostic (1.84e-2)" "unprognostic (1.20e-3)" "unprognostic (6.09e-2)" "unprognostic (1.21e-2)" "unprognostic (1.45e-1)" "unprognostic (1.52e-1)" "unprognostic (2.36e-3)" "unprognostic (1.37e-1)" C18orf32 FLJ23458 ENSG00000177576 "Chromosome 18 open reading frame 32" Q8TCD1 18 49477243-49487252 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 288.8" "Cell type enhanced" "Detected in many" "Early spermatids: 150.6;Late spermatids: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040921 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 11: Late spermatids - Unknown function" Vesicles Nucleoplasm "HPA040921: AB_10795423" "unprognostic (5.83e-2)" "unprognostic (5.48e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-2)" "unprognostic (4.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-2)" "unprognostic (6.36e-2)" "unprognostic (4.36e-3)" "unprognostic (2.58e-3)" "unprognostic (2.76e-2)" "prognostic favorable (8.89e-9)" "unprognostic (1.02e-1)" "unprognostic (7.42e-2)" "unprognostic (1.28e-2)" "unprognostic (4.36e-2)" C19orf18 MGC41906 ENSG00000177025 "Chromosome 19 open reading frame 18" Q8NEA5 19 57958437-57974534 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.6;testis: 12.0" "Cell type enriched" "Detected in many" 6 "Early spermatids: 176.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA014527, HPA079195" Approved Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 18: Early spermatids - Unknown function" 3 "Golgi apparatus" "HPA014527: AB_1845612, HPA079195: " "unprognostic (5.38e-2)" "unprognostic (6.36e-3)" "unprognostic (3.70e-2)" "prognostic favorable (5.07e-4)" "unprognostic (4.85e-2)" "unprognostic (9.50e-2)" "unprognostic (2.75e-1)" "unprognostic (5.40e-3)" "unprognostic (5.78e-2)" "unprognostic (1.64e-1)" "unprognostic (4.08e-5)" "unprognostic (1.11e-2)" "unprognostic (8.75e-5)" "unprognostic (1.53e-1)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (1.05e-3)" C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 96.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.7;Kupffer cells: 78.8;Langerhans cells: 30.8;Macrophages: 49.4;monocytes: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.7;eosinophil: 169.8;intermediate monocyte: 312.8;myeloid DC: 162.4;neutrophil: 231.0;non-classical monocyte: 394.4" "Group enriched" "Detected in all" 20 "dendritic cells: 162.4;granulocytes: 231.0;monocytes: 394.4" "Group enriched" "Detected in some" 5 "Leukemia: 12.4;lymphoma: 6.1;Myeloma: 5.7" "Kidney - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: AB_10603448, HPA055027: " "unprognostic (6.65e-3)" "prognostic favorable (2.43e-4)" "unprognostic (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-3)" "unprognostic (3.56e-1)" "unprognostic (8.27e-2)" "unprognostic (5.60e-2)" "unprognostic (6.02e-2)" "unprognostic (9.74e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.75e-7)" "unprognostic (2.31e-1)" "unprognostic (4.00e-2)" "unprognostic (1.03e-2)" "unprognostic (2.11e-2)" C1GALT1C1 "C1GALT2, COSMC" ENSG00000171155 "C1GALT1 specific chaperone 1" Q96EU7 X 120625674-120630054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 106.3;Ionocytes: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010666, HPA015632" Approved Approved Vesicles NA NA 21000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA010666: , HPA015632: AB_1845625" "prognostic unfavorable (5.66e-4)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (5.26e-3)" "unprognostic (4.34e-2)" "unprognostic (2.50e-1)" "unprognostic (2.18e-2)" "unprognostic (8.10e-2)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (4.48e-2)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (3.78e-2)" C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 64.4;Late spermatids: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.8;lymphoid tissue: 131.3" "Cell type enhanced" "Detected in many" "granulocytes: 245.3;Hofbauer cells: 355.7;Kupffer cells: 721.5;Langerhans cells: 253.6;Macrophages: 424.5;monocytes: 442.9;NK-cells: 190.6;Schwann cells: 443.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 22.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.1;Enteroendocrine cells: 46.7;Paneth cells: 62.0;Proximal enterocytes: 134.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" C1orf43 "DKFZp586G1722, NICE-3" ENSG00000143612 "Chromosome 1 open reading frame 43" Q9BWL3 1 154206696-154220637 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010725 Approved Supported Mitochondria,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA010725: AB_1078341" "unprognostic (3.90e-2)" "unprognostic (1.22e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.87e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (3.51e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-2)" "unprognostic (1.23e-1)" C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 973.1" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1340.6;Kupffer cells: 3907.0;Macrophages: 1814.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 142.5;non-classical monocyte: 103.0" "Lineage enriched" "Detected in many" 83 "monocytes: 142.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" "Complement pathway" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" C20orf141 dJ860F19.4 ENSG00000258713 "Chromosome 20 open reading frame 141" Q9NUB4 20 2814987-2815833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "testis: 126.6" "Cell type enriched" "Detected in some" 6 "Late spermatids: 4681.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA077873 Approved "Vesicles,Plasma membrane" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 63: Late spermatids - Spermatogenesis" 4 "Plasma membrane" Vesicles "HPA077873: " "unprognostic (4.52e-1)" "unprognostic (1.40e-2)" "unprognostic (1.35e-2)" "unprognostic (7.53e-2)" "unprognostic (1.21e-2)" C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 31 "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" C2orf16 DKFZp434G118 ENSG00000221843 "Chromosome 2 open reading frame 16" 2 27537386-27582722 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "retina: 1.5;testis: 5.5" "Group enriched" "Detected in some" 38 "Early spermatids: 427.0;Late spermatids: 121.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052136, HPA056962" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 39: Retina & Testis - Cilium" "Cluster 24: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 21: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA052136: AB_2681742, HPA056962: AB_2683290" "unprognostic (4.32e-2)" "unprognostic (1.08e-2)" "unprognostic (8.36e-2)" "unprognostic (3.40e-3)" "unprognostic (6.36e-2)" "unprognostic (6.17e-2)" "unprognostic (6.15e-2)" "unprognostic (3.07e-1)" "unprognostic (9.35e-2)" "unprognostic (3.79e-3)" "unprognostic (4.59e-1)" "unprognostic (2.19e-2)" "unprognostic (8.82e-2)" "unprognostic (8.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-2)" "unprognostic (8.53e-3)" C2orf74 LOC339804 ENSG00000237651 "Chromosome 2 open reading frame 74" A8MZ97 2 61145068-61164828 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.4;Early spermatids: 17.8;Proximal tubular cells: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026826 Approved Approved Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" 1 Centrosome "HPA026826: AB_10671091" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (4.54e-2)" "unprognostic (8.10e-2)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (1.28e-3)" "unprognostic (3.57e-2)" "unprognostic (1.87e-1)" "unprognostic (1.54e-1)" "unprognostic (2.69e-2)" "unprognostic (6.65e-2)" "unprognostic (3.52e-1)" "unprognostic (6.22e-2)" C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.0" "Group enriched" "Detected in many" 5 "granulocytes: 59.3;Hofbauer cells: 171.3;Kupffer cells: 155.4;Macrophages: 151.8;monocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 902.8;eosinophil: 452.5;intermediate monocyte: 274.2;non-classical monocyte: 373.1" "Group enriched" "Detected in many" 20 "granulocytes: 902.8;monocytes: 373.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 32.4;Early spermatids: 49.2;Late spermatids: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 36: Late spermatids - Unknown function" Cytosol "HPA012105: AB_1845717" "unprognostic (9.29e-3)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.19e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.80e-9)" "unprognostic (7.65e-2)" "unprognostic (4.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 16.9;skin 1: 25.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Basal squamous epithelial cells: 50.5;Gastric mucus-secreting cells: 57.2;Intestinal goblet cells: 64.7;Syncytiotrophoblasts: 81.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 57 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" C3orf80 ENSG00000180044 "Chromosome 3 open reading frame 80" F5H4A9 3 160225422-160228213 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 13.7;esophagus: 4.5;intestine: 7.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 7.4;Excitatory neurons: 22.8;Horizontal cells: 4.4;Inhibitory neurons: 6.1;Oligodendrocytes: 5.6;Spermatocytes: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 8.6" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047439 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA047439: AB_10965171" "unprognostic (5.34e-2)" "unprognostic (2.31e-1)" "unprognostic (6.35e-2)" "unprognostic (6.62e-3)" "unprognostic (1.92e-3)" "unprognostic (6.70e-3)" "unprognostic (4.28e-3)" "unprognostic (1.69e-1)" "unprognostic (4.64e-3)" "unprognostic (1.51e-1)" "unprognostic (9.20e-2)" "unprognostic (2.65e-1)" "unprognostic (6.09e-10)" "unprognostic (1.32e-2)" "unprognostic (1.78e-2)" "unprognostic (4.11e-3)" "unprognostic (5.00e-2)" C4orf3 "ALN, HCVFTP1" ENSG00000164096 "Chromosome 4 open reading frame 3" Q8WVX3 4 119296419-119304445 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 985.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026907 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum" "HPA026907: AB_10600760" "unprognostic (2.97e-1)" "unprognostic (4.68e-2)" "unprognostic (3.32e-1)" "unprognostic (6.85e-3)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (2.04e-1)" "unprognostic (8.85e-2)" "unprognostic (4.90e-2)" "unprognostic (7.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.84e-1)" "prognostic favorable (3.46e-4)" "unprognostic (8.32e-2)" "unprognostic (2.65e-1)" "unprognostic (3.90e-1)" "unprognostic (1.59e-1)" C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 124.0;lymphoid tissue: 82.5" "Cell type enriched" "Detected in many" 7 "monocytes: 3492.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 393.7" "Group enriched" "Detected in many" 42 "granulocytes: 393.7;monocytes: 116.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Heart muscle - Macrophages, Kidney - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement C5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enriched" "Detected in many" 5 "monocytes: 266.2" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.1" "Cancer enhanced" "Detected in some" "breast cancer: 5.6;Leukemia: 3.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" C5orf15 "HTGN29, KCT2" ENSG00000113583 "Chromosome 5 open reading frame 15" Q8NC54 5 133955510-133968674 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011951, HPA039165" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA011951: AB_2668584, HPA039165: AB_10795580" "unprognostic (2.25e-1)" "unprognostic (3.01e-1)" "unprognostic (2.07e-1)" "unprognostic (4.91e-2)" "unprognostic (1.81e-1)" "unprognostic (2.26e-3)" "unprognostic (1.01e-2)" "unprognostic (7.72e-2)" "unprognostic (2.62e-2)" "unprognostic (7.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (9.07e-3)" "unprognostic (5.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-2)" C6orf136 Em:AB023049.8 ENSG00000204564 "Chromosome 6 open reading frame 136" Q5SQH8 6 30647039-30653210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 87.7;Oocytes: 99.3;Proximal enterocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046804 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 5: Enterocytes - Absorption" "HPA046804: AB_2679815" "unprognostic (1.94e-2)" "unprognostic (1.71e-3)" "unprognostic (1.26e-1)" "unprognostic (8.01e-3)" "unprognostic (1.65e-2)" "unprognostic (2.76e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (4.72e-3)" "unprognostic (3.43e-1)" "prognostic favorable (9.16e-8)" "unprognostic (2.33e-2)" "unprognostic (4.54e-2)" "unprognostic (6.03e-2)" "prognostic favorable (7.51e-4)" C6orf47 "D6S53E, G4" ENSG00000204439 "Chromosome 6 open reading frame 47" O95873 6 31658298-31660778 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045281 Uncertain Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 5: Enterocytes - Absorption" 3 Cytosol "HPA045281: AB_10961000" "unprognostic (5.99e-2)" "unprognostic (5.71e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (6.74e-2)" "unprognostic (2.09e-1)" "unprognostic (3.24e-2)" "unprognostic (3.27e-1)" "unprognostic (5.04e-2)" "unprognostic (2.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.66e-3)" "unprognostic (6.78e-3)" "unprognostic (2.38e-1)" "unprognostic (7.73e-2)" "unprognostic (3.59e-3)" C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 268.7;Late spermatids: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Thyroid gland - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" "HPA012548: AB_1845748" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.77e-5)" "unprognostic (3.75e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-3)" "unprognostic (8.42e-3)" CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 149.3;kidney: 280.0;skin 1: 138.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 145.6;Basal squamous epithelial cells: 124.3;Distal enterocytes: 349.5;Intestinal goblet cells: 117.1;Paneth cells: 129.7;Squamous epithelial cells: 182.1;Suprabasal keratinocytes: 192.1" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Group enriched" "Detected in all" 5 "basal ganglia: 92.5;choroid plexus: 274.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 208.5" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 52000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394, HPA073203: AB_2686580" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 116.2;retina: 38.2;tongue: 45.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 56.6;Melanocytes: 68.7;Muller glia cells: 151.4;Oligodendrocytes: 23.9" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Rhabdoid: 29.1;skin cancer: 20.9;testis cancer: 13.5" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Melanocytes, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 10: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 254.9" "Cell type enriched" "Detected in many" 5 "Paneth cells: 4309.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Region enriched" "Detected in all" 5 "cerebellum: 173.8" "Immune cell enriched" "Detected in some" 7 "neutrophil: 100.0" "Lineage enriched" "Detected in single" 1000 "granulocytes: 100.0" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;liver cancer: 7.8;prostate cancer: 7.4" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 5: Enterocytes - Absorption" 1 Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673928-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 281.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 255.4;Early spermatids: 188.9;Gastric mucus-secreting cells: 251.7;Late spermatids: 58.5;Mesothelial cells: 59.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in some" 9 "cerebellum: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 114.9" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" CABLES2 "C20orf150, dJ908M14.2, ik3-2" ENSG00000149679 "Cdk5 and Abl enzyme substrate 2" Q9BTV7 20 62388634-62407285 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 30.2" "Cell type enhanced" "Detected in many" "Early spermatids: 61.1;Late spermatids: 26.3;Spermatocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043597 Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Early spermatids - Unknown function" Nucleoli "HPA043597: " "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.26e-5)" "unprognostic (1.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.71e-2)" "unprognostic (5.07e-2)" "unprognostic (5.37e-3)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (1.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (2.94e-2)" CABP7 MGC57793 ENSG00000100314 "Calcium binding protein 7" Q86V35 22 29720003-29731833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 55.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Inhibitory neurons: 1.0;Muller glia cells: 1.1;Oligodendrocyte precursor cells: 1.4;Rod photoreceptor cells: 1.1" "Group enriched" "Detected in some" 4 "glioma: 2.3;ovarian cancer: 1.0;pancreatic cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.8" "Pancreas - Beta cells, Thyroid - Parafollicular cells" "Group enriched" "Detected in all" 4 "cerebellum: 74.4;hippocampal formation: 205.0;midbrain: 60.3;pons and medulla: 110.0" "Region enhanced" "Detected in all" "hippocampal formation: 77.5" HPA016439 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "HPA016439: AB_2669357" "unprognostic (1.88e-1)" "unprognostic (4.75e-2)" "unprognostic (1.18e-1)" "unprognostic (5.37e-2)" "unprognostic (4.55e-1)" "unprognostic (2.29e-4)" "unprognostic (2.05e-3)" "unprognostic (7.96e-2)" "unprognostic (8.69e-3)" "unprognostic (3.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (7.44e-7)" "unprognostic (1.25e-4)" "unprognostic (3.60e-2)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" CACFD1 "C9orf7, D9S2135, flower" ENSG00000160325 "Calcium channel flower domain containing 1" Q9UGQ2 9 133459965-133470848 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 70.8;Gastric mucus-secreting cells: 57.2;Intestinal goblet cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Group enriched" "Detected in many" 4 "B-cells: 2.0;granulocytes: 3.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015280 Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 7 Nucleoplasm "HPA015280: AB_1845833" "unprognostic (3.15e-2)" "unprognostic (4.25e-1)" "unprognostic (1.96e-3)" "unprognostic (4.48e-1)" "unprognostic (2.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-2)" "unprognostic (5.49e-2)" "unprognostic (3.97e-1)" "unprognostic (3.17e-1)" "unprognostic (1.67e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.83e-8)" "unprognostic (5.10e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (3.99e-3)" CACHD1 "KIAA1573, VWCD1" ENSG00000158966 "Cache domain containing 1" Q5VU97 1 64470129-64693058 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Astrocytes: 269.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017202 Uncertain Uncertain Nucleoplasm,Nucleoli NA NA 310000 "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 47: Astrocytes - Unknown function" "Nucleoplasm, Nucleoli" "HPA017202: AB_1852423" "unprognostic (2.92e-2)" "unprognostic (2.91e-1)" "unprognostic (1.29e-2)" "unprognostic (1.02e-1)" "unprognostic (3.75e-1)" "unprognostic (1.01e-1)" "unprognostic (4.82e-2)" "unprognostic (4.32e-2)" "unprognostic (6.77e-2)" "unprognostic (1.33e-1)" "unprognostic (8.16e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-3)" "unprognostic (2.67e-2)" "unprognostic (3.89e-1)" "unprognostic (3.65e-1)" "unprognostic (2.13e-1)" CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "brain: 240.4" "Group enriched" "Detected in many" 7 "Bipolar cells: 145.9;Enteroendocrine cells: 228.5;Excitatory neurons: 307.8;Horizontal cells: 429.9;Inhibitory neurons: 356.4;Oligodendrocyte precursor cells: 255.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 218.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.2;lung cancer: 8.4;Rhabdoid: 8.2" "Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 18 "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.1" "Group enriched" "Detected in some" 8 "Excitatory neurons: 375.5;Inhibitory neurons: 316.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022919, HPA044347" Uncertain Approved Mitochondria NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 Mitochondria "HPA022919: , HPA044347: AB_10960837" "unprognostic (1.34e-3)" "unprognostic (2.70e-2)" "unprognostic (8.08e-2)" "unprognostic (2.51e-7)" "unprognostic (8.10e-2)" "unprognostic (1.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (9.73e-4)" "unprognostic (5.98e-2)" "unprognostic (6.63e-6)" "unprognostic (4.25e-2)" "unprognostic (4.72e-1)" "unprognostic (7.77e-3)" "unprognostic (8.69e-2)" CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970772-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.5;heart muscle: 20.2;intestine: 28.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 586.4;Inhibitory neurons: 456.6;Oligodendrocyte precursor cells: 182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" 3 "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 242.8;Horizontal cells: 112.0;Inhibitory neurons: 339.0;Microglial cells: 120.8;Oligodendrocyte precursor cells: 185.4" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.7" "Lineage enriched" "Detected in single" 20 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181813262 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 182.2;Inhibitory neurons: 110.6;Oligodendrocyte precursor cells: 69.3;Oligodendrocytes: 31.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.4;lung cancer: 2.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" CACNA1F "AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2" ENSG00000102001 "Calcium voltage-gated channel subunit alpha1 F" O60840 X 49205063-49233371 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Transport, Vision" "Calcium channel, Ion channel, Voltage-gated channel" "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "retina: 121.4" "Group enriched" "Detected in some" 7 "Bipolar cells: 66.4;Cone photoreceptor cells: 73.1;Rod photoreceptor cells: 91.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA068379 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA068379: AB_2732782" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (4.25e-3)" "unprognostic (1.56e-2)" "unprognostic (8.46e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.04e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (6.08e-7)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.65e-2)" "unprognostic (3.77e-3)" CACNA1G "Cav3.1, NBR13" ENSG00000006283 "Calcium voltage-gated channel subunit alpha1 G" O43497 17 50560715-50627474 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.5;cervix: 9.5;retina: 8.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 152.8;Horizontal cells: 68.0" "Cancer enhanced" "Detected in some" "glioma: 1.6;testis cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.8" "Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004714 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA004714: AB_1078368" "unprognostic (1.90e-2)" "unprognostic (5.83e-2)" "unprognostic (2.85e-2)" "unprognostic (1.08e-1)" "unprognostic (4.00e-1)" "unprognostic (9.89e-2)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "unprognostic (1.02e-4)" "unprognostic (1.47e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (4.87e-12)" "unprognostic (3.34e-2)" "unprognostic (1.62e-1)" "unprognostic (1.56e-3)" "unprognostic (6.63e-2)" CACNA1H Cav3.2 ENSG00000196557 "Calcium voltage-gated channel subunit alpha1 H" O95180 16 1153106-1221771 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 104.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.0;Enteroendocrine cells: 13.1;Horizontal cells: 12.0;Late spermatids: 14.5;Ovarian stromal cells: 17.9;Peritubular cells: 22.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039125 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoplasm, Vesicles" "HPA039125: AB_10795578" "unprognostic (1.66e-3)" "unprognostic (2.10e-1)" "unprognostic (4.07e-2)" "unprognostic (1.21e-3)" "unprognostic (1.37e-2)" "unprognostic (2.15e-1)" "unprognostic (4.39e-2)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" "prognostic favorable (3.12e-5)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.93e-2)" "unprognostic (4.65e-2)" "unprognostic (1.70e-2)" "unprognostic (5.55e-2)" CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.9;thyroid gland: 5.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 13.5;Excitatory neurons: 16.3;Horizontal cells: 30.2;Inhibitory neurons: 11.7" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8;Rhabdoid: 1.3" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066992 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Plasma membrane" "Cell Junctions" "HPA066992: " "unprognostic (3.97e-2)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-1)" "unprognostic (7.21e-2)" "unprognostic (5.20e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-2)" "unprognostic (6.14e-3)" "unprognostic (1.57e-1)" "unprognostic (3.78e-2)" "unprognostic (8.27e-4)" CACNA1S "CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5" ENSG00000081248 "Calcium voltage-gated channel subunit alpha1 S" Q13698 1 201039512-201112451 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 85 "skeletal muscle: 245.8;tongue: 185.7" "Cell type enriched" "Detected in some" 15 "Skeletal myocytes: 106.4" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.1" "Adipose visceral - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.8" "CAB009507, HPA048892, HPA056815" Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 4 "CAB009507: AB_2069576, HPA048892: AB_2680548, HPA056815: AB_2683242" "unprognostic (2.14e-2)" "unprognostic (1.38e-1)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.52e-3)" "unprognostic (4.53e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (4.72e-3)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-1)" CACNA2D1 "alpha2delta-1, CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3" ENSG00000153956 "Calcium voltage-gated channel auxiliary subunit alpha2delta 1" P54289 7 81946444-82443956 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 74.7;tongue: 72.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 524.8;Inhibitory neurons: 365.9;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 616.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008213, HPA008621" Enhanced "Intracellular and membrane" Transport NA NA 390000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "HPA008213: AB_1233654, HPA008621: AB_1845863" "unprognostic (5.07e-3)" "unprognostic (2.21e-1)" "unprognostic (4.27e-3)" "unprognostic (2.92e-2)" "unprognostic (2.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (3.22e-1)" "unprognostic (3.76e-1)" "unprognostic (2.05e-1)" "unprognostic (6.24e-3)" "unprognostic (2.23e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (4.28e-3)" "unprognostic (2.13e-1)" "unprognostic (9.18e-2)" "unprognostic (1.03e-4)" CACNA2D3 "alpha2delta-3, HSA272268" ENSG00000157445 "Calcium voltage-gated channel auxiliary subunit alpha2delta 3" Q8IZS8 3 54122547-55074557 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2;skeletal muscle: 9.5;tongue: 10.3" "Cell type enhanced" "Detected in many" "Astrocytes: 152.7;Excitatory neurons: 800.8;Inhibitory neurons: 435.8;Oligodendrocyte precursor cells: 298.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030849 Uncertain Nucleoplasm NA NA 69000 "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm "HPA030849: " "unprognostic (6.92e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-5)" "unprognostic (5.53e-3)" "unprognostic (2.64e-3)" "unprognostic (3.24e-1)" "unprognostic (1.17e-2)" "unprognostic (5.84e-3)" "unprognostic (7.22e-3)" "unprognostic (1.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.00e-1)" "unprognostic (1.47e-3)" "unprognostic (2.19e-1)" "unprognostic (3.62e-2)" "unprognostic (6.95e-2)" CACNA2D4 alpha2delta-4 ENSG00000151062 "Calcium voltage-gated channel auxiliary subunit alpha2delta 4" Q7Z3S7 12 1791963-1918666 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "retina: 19.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.1;Cone photoreceptor cells: 79.9;Hofbauer cells: 32.6;Late spermatids: 125.0;Rod photoreceptor cells: 97.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 4.4;T-cells: 4.2" "Group enriched" "Detected in some" 4 "Leukemia: 7.5;lymphoma: 3.1;Sarcoma: 2.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA031952 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Retina - Visual perception" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 11: Late spermatids - Unknown function" "HPA031952: AB_10600798" "unprognostic (5.04e-2)" "unprognostic (2.82e-2)" "unprognostic (5.32e-1)" "unprognostic (7.50e-2)" "unprognostic (1.15e-1)" "unprognostic (8.18e-4)" "unprognostic (1.10e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" "unprognostic (3.30e-3)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-5)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (2.13e-1)" CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 24.5;skin 1: 7.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 478.6;Horizontal cells: 107.0;Inhibitory neurons: 452.4;Microglial cells: 130.6;Oligodendrocyte precursor cells: 145.7" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA015601: AB_1845873" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.49e-2)" "unprognostic (3.70e-1)" "unprognostic (9.42e-4)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.55e-2)" "unprognostic (7.26e-3)" "unprognostic (3.93e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" CACNG3 ENSG00000006116 "Calcium voltage-gated channel auxiliary subunit gamma 3" O60359 16 24256335-24362412 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 42.7;retina: 17.1" "Group enriched" "Detected in some" 15 "Excitatory neurons: 151.9;Horizontal cells: 57.9;Inhibitory neurons: 102.8" "Cancer enriched" "Detected in single" 15 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "Bone cancer: 3.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077238 Enhanced NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA077238: " "unprognostic (5.61e-2)" "unprognostic (3.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.17e-1)" CACNG4 "MGC11138, MGC24983" ENSG00000075461 "Calcium voltage-gated channel auxiliary subunit gamma 4" Q9UBN1 17 66964707-67033398 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 60.8" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 35.0;Oligodendrocyte precursor cells: 136.3" "Group enriched" "Detected in many" 5 "breast cancer: 30.3;glioma: 35.8;ovarian cancer: 14.8;prostate cancer: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 65.6" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 155.8" "HPA005803, HPA065370" Enhanced Approved Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA005803: AB_2667439, HPA065370: AB_2685480" "unprognostic (1.27e-1)" "unprognostic (3.16e-1)" "unprognostic (8.87e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-2)" "unprognostic (8.64e-3)" "unprognostic (2.91e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-2)" "unprognostic (3.85e-2)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (2.38e-10)" "unprognostic (8.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.71e-2)" "unprognostic (4.28e-1)" CACNG5 ENSG00000075429 "Calcium voltage-gated channel auxiliary subunit gamma 5" Q9UF02 17 66835117-66894751 "FDA approved drug targets, Predicted membrane proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "retina: 15.3" "Group enriched" "Detected in some" 4 "Horizontal cells: 91.3;Oligodendrocyte precursor cells: 70.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;breast cancer: 1.5;prostate cancer: 1.0" "Region enhanced" "Detected in all" "olfactory bulb: 124.3" "Low region specificity" "Detected in many" HPA050115 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA050115: AB_2681022" "unprognostic (1.85e-3)" "unprognostic (3.84e-2)" "unprognostic (1.44e-1)" "unprognostic (2.46e-6)" "unprognostic (4.52e-2)" "unprognostic (1.29e-1)" CACNG6 ENSG00000130433 "Calcium voltage-gated channel auxiliary subunit gamma 6" Q9BXT2 19 53991637-54012666 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 87.5;tongue: 28.8" "Group enriched" "Detected in some" 11 "Ciliated cells: 14.5;Skeletal myocytes: 32.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 107 "basophil: 13.4;eosinophil: 8.0" "Lineage enriched" "Detected in single" 134 "granulocytes: 13.4" "Cancer enhanced" "Detected in many" "Myeloma: 11.9;pancreatic cancer: 12.2" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056615 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoli fibrillar center" Cytosol "HPA056615: AB_2683192" "unprognostic (1.83e-1)" "unprognostic (9.51e-2)" "unprognostic (7.07e-2)" "unprognostic (8.58e-2)" "unprognostic (2.89e-2)" "unprognostic (2.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.72e-1)" "unprognostic (1.53e-1)" "unprognostic (6.07e-8)" "unprognostic (9.79e-2)" "unprognostic (1.28e-1)" CACNG8 ENSG00000142408 "Calcium voltage-gated channel auxiliary subunit gamma 8" Q8WXS5 19 53962937-53990215 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "brain: 36.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 59.8;Horizontal cells: 40.3;Inhibitory neurons: 63.1;Oligodendrocyte precursor cells: 27.8;Skeletal myocytes: 13.7" "Cancer enriched" "Detected in single" 5 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 5.4" "Lineage enriched" "Detected in single" 29 "granulocytes: 5.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041351 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA041351: AB_10796666" "unprognostic (7.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.06e-1)" "unprognostic (5.29e-4)" "unprognostic (9.66e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (9.40e-3)" "unprognostic (6.13e-2)" "unprognostic (2.03e-1)" "unprognostic (7.63e-2)" "unprognostic (2.58e-1)" "unprognostic (2.82e-8)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" CADM1 "BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1" ENSG00000182985 "Cell adhesion molecule 1" Q9BY67 11 115169218-115504957 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 278.9" "Cell type enhanced" "Detected in many" "Astrocytes: 930.1;Bipolar cells: 517.1;Muller glia cells: 421.6;Oligodendrocyte precursor cells: 634.9;Oligodendrocytes: 579.5;Rod photoreceptor cells: 752.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.0;myeloid DC: 8.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.1;T-cells: 8.0" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037266 Enhanced Supported "Cell Junctions" NA NA 220000000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Astrocytes - Unknown function" 1 "Cell Junctions" "CAB037266: AB_532287" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "prognostic favorable (1.32e-4)" "unprognostic (4.11e-3)" "unprognostic (1.50e-1)" "unprognostic (2.75e-3)" "unprognostic (1.13e-2)" "unprognostic (1.77e-1)" "unprognostic (2.67e-1)" "unprognostic (6.61e-3)" "unprognostic (9.22e-2)" "unprognostic (2.92e-3)" "unprognostic (1.77e-2)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (5.40e-2)" CADM2 "IGSF4D, Necl-3, NECL3, SynCAM2" ENSG00000175161 "Cell adhesion molecule 2" Q8N3J6 3 84958989-86074429 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 15 "brain: 50.2;retina: 92.0" "Group enriched" "Detected in many" 6 "Astrocytes: 1882.9;Excitatory neurons: 3959.7;Inhibitory neurons: 3478.8;Oligodendrocyte precursor cells: 3390.8;Oligodendrocytes: 4708.9" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.0" "Cancer enhanced" "Detected in some" "Rhabdoid: 11.1;Sarcoma: 8.5" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010024 Enhanced NA NA 250000 "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "HPA010024: AB_2068039" "unprognostic (2.23e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-4)" "unprognostic (8.64e-2)" "unprognostic (2.27e-1)" "unprognostic (4.76e-3)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (1.90e-1)" "unprognostic (8.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.07e-5)" "unprognostic (9.82e-3)" "unprognostic (1.26e-2)" "unprognostic (4.17e-3)" "unprognostic (1.16e-2)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 336.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 118.4;Excitatory neurons: 34.3;Horizontal cells: 55.4;Inhibitory neurons: 38.7;Melanocytes: 63.6;Muller glia cells: 31.9;Schwann cells: 88.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 55.7;skin cancer: 20.6" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" "Cell adhesion" NA NA 800000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" CADM4 "IGSF4C, Necl-4, SynCAM4, TSLL2" ENSG00000105767 "Cell adhesion molecule 4" Q8NFZ8 19 43622368-43639850 "Predicted membrane proteins" "Cell adhesion" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 204.7" "Cell type enhanced" "Detected in many" "Melanocytes: 34.4;Oligodendrocyte precursor cells: 39.6;Oligodendrocytes: 47.3;Schwann cells: 75.5" "Cancer enhanced" "Detected in all" "glioma: 108.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 7 "dendritic cells: 1.5" "Cancer enhanced" "Detected in all" "skin cancer: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012612 Enhanced Uncertain "Nucleoplasm,Nuclear membrane" NA NA 8200000 "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Nuclear membrane" Nucleoplasm "HPA012612: AB_1851530" "unprognostic (8.80e-3)" "unprognostic (2.57e-2)" "unprognostic (3.61e-3)" "unprognostic (3.53e-1)" "unprognostic (2.87e-1)" "unprognostic (9.29e-3)" "unprognostic (1.78e-1)" "unprognostic (1.77e-1)" "unprognostic (2.77e-1)" "unprognostic (5.03e-1)" "unprognostic (3.19e-3)" "unprognostic (3.81e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.39e-1)" "unprognostic (3.35e-2)" "unprognostic (2.59e-1)" "unprognostic (3.93e-2)" CALCR "CT-R, CTR" ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;kidney: 1.4" "Group enriched" "Detected in some" 5 "Early spermatids: 17.8;Late spermatids: 9.2;Microglial cells: 15.2" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.6;Uterine cancer: 2.9" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 68.3;lung: 74.4" "Cell type enhanced" "Detected in many" "Adipocytes: 131.7;Endometrial stromal cells: 98.4;Endothelial cells: 262.9;Lymphatic endothelial cells: 297.8;Oligodendrocyte precursor cells: 275.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.7;Sarcoma: 23.1" "Colon - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" CALHM1 FAM26C ENSG00000185933 "Calcium homeostasis modulator 1" Q8IU99 10 103453240-103458900 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sensory transduction, Taste, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.0" "Cell type enhanced" "Detected in single" "Excitatory neurons: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061816 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA061816: " "unprognostic (2.46e-1)" "unprognostic (2.66e-1)" "unprognostic (2.38e-1)" "unprognostic (1.30e-1)" "unprognostic (5.65e-3)" "unprognostic (3.44e-2)" "unprognostic (2.86e-2)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (3.44e-1)" "unprognostic (2.21e-8)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" "unprognostic (1.38e-2)" CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 85.9;Fibroblasts: 38.3;Hofbauer cells: 48.5;Leydig cells: 44.9;Ovarian stromal cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" CALHM3 "bA225H22.7, FAM26A" ENSG00000183128 "Calcium homeostasis modulator 3" Q86XJ0 10 103472804-103479240 "Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Taste, Transport" "Ion channel" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.6;Extravillous trophoblasts: 8.1;Late spermatids: 2.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 5.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA018205 Uncertain NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA018205: AB_2069267" "unprognostic (2.88e-1)" "unprognostic (4.00e-1)" "unprognostic (3.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.87e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (1.44e-1)" "unprognostic (4.89e-2)" "unprognostic (3.07e-1)" "unprognostic (5.05e-2)" "unprognostic (1.53e-1)" CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116561127 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 22.5" "Group enriched" "Detected in some" 47 "Cytotrophoblasts: 26.9;Syncytiotrophoblasts: 86.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.6" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA048014: " "unprognostic (7.95e-2)" "unprognostic (3.44e-4)" "unprognostic (1.99e-1)" "unprognostic (1.44e-2)" CALHM5 "C6orf188, dJ493F7.3, FAM26E, MGC45451" ENSG00000178033 "Calcium homeostasis modulator family member 5" Q8N5C1 6 116511639-116524788 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.3;Early spermatids: 3.8;Endothelial cells: 4.8;Fibroblasts: 6.0;Peritubular cells: 4.0;Schwann cells: 4.2;Sertoli cells: 5.4;Smooth muscle cells: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034969, HPA034970" Uncertain Approved "Golgi apparatus" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Golgi apparatus" "HPA034969: AB_10670299, HPA034970: AB_2674390" "unprognostic (2.71e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (3.92e-1)" "unprognostic (1.93e-2)" "unprognostic (5.37e-2)" "unprognostic (4.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.06e-1)" "unprognostic (9.16e-2)" "unprognostic (1.24e-7)" "unprognostic (1.16e-2)" "unprognostic (2.98e-2)" "unprognostic (7.69e-2)" "unprognostic (6.65e-3)" CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 56.6;lymphoid tissue: 24.1" "Cell type enhanced" "Detected in some" "Astrocytes: 84.2;Excitatory neurons: 126.0;Inhibitory neurons: 204.1;Oligodendrocyte precursor cells: 42.0;Oocytes: 67.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.1;Leukemia: 2.4;Myeloma: 8.5;Neuroblastoma: 2.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 69: Neurons - Neuronal signaling" 7 Vesicles "Plasma membrane" "HPA036278: AB_10673125, HPA036708: " "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-2)" "unprognostic (3.67e-4)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (7.72e-4)" "unprognostic (2.99e-1)" CALY "CALCYON, DRD1IP, NSG3" ENSG00000130643 "Calcyon neuron specific vesicular protein" Q9NYX4 10 133324072-133336935 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 305.6;pituitary gland: 163.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 130.9;Excitatory neurons: 70.1;Horizontal cells: 95.7;Inhibitory neurons: 122.9" "Cancer enriched" "Detected in some" 4 "pancreatic cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5;Rhabdoid: 2.4" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042283 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 25: Bipolar cells - Visual perception" 1 "HPA042283: AB_10794417" "unprognostic (1.43e-2)" "unprognostic (7.84e-2)" "unprognostic (3.77e-3)" "unprognostic (1.41e-2)" "unprognostic (7.32e-2)" "unprognostic (9.81e-3)" "unprognostic (2.56e-1)" "unprognostic (7.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "prognostic favorable (3.54e-4)" "unprognostic (1.23e-2)" "unprognostic (4.19e-10)" "unprognostic (8.04e-3)" "unprognostic (1.29e-1)" "unprognostic (3.60e-1)" "unprognostic (1.63e-1)" CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 96.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 84.4;monocytes: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "eosinophil: 281.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 281.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 110000 "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349547-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;retina: 56.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 331.3;Excitatory neurons: 403.0;Inhibitory neurons: 224.4;Microglial cells: 161.0;Rod photoreceptor cells: 220.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 64.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" 1 "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favorable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" CAMK2A "CAMKA, CaMKIIalpha, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290093 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 438.1;skeletal muscle: 158.1" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 237.9" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 5 "amygdala: 795.7;basal ganglia: 786.5;cerebral cortex: 1817.1;hippocampal formation: 1345.8;white matter: 633.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.3" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 1422.5" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 66000 "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 52 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIbeta" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44210019-44334577 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 107.3;heart muscle: 64.3;skeletal muscle: 115.6;tongue: 59.1" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 697.3" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.1" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 79: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 25: Bipolar cells - Visual perception" 19 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113418054-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 127.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 342.0;Inhibitory neurons: 192.1;Microglial cells: 178.9;Oligodendrocyte precursor cells: 190.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 240000 "Cluster 18: Non-specific - Translation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 147.2" "Cell type enhanced" "Detected in many" "Astrocytes: 389.5;Cytotrophoblasts: 173.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 128.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA 200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 53.5;lymphoid tissue: 54.0" "Cell type enhanced" "Detected in many" "Early spermatids: 392.0;Excitatory neurons: 204.9;Inhibitory neurons: 126.0;Late spermatids: 116.6;Oligodendrocyte precursor cells: 125.0;T-cells: 91.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 174.1" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.4;memory CD8 T-cell: 13.4;naive CD4 T-cell: 33.2;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.2" "Cancer enhanced" "Detected in many" "lymphoma: 17.8;Neuroblastoma: 27.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - Hepatic stellate cells, Skin - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237675-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 363.3" "Cell type enhanced" "Detected in many" "Late spermatids: 89.0" "Cancer enriched" "Detected in all" 5 "prostate cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 32.8;eosinophil: 62.2;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.4;non-classical monocyte: 39.7" "Group enriched" "Detected in all" 5 "dendritic cells: 15.9;granulocytes: 62.2;monocytes: 42.3" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 716.7;Late spermatids: 1729.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 25: Non-specific - Ribosome" "Cluster 36: Late spermatids - Unknown function" 18 Vesicles "Nucleoplasm, Nucleoli" "HPA052636: AB_2681893, HPA056472: AB_2683143" "unprognostic (9.23e-2)" "unprognostic (8.54e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (3.07e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (4.58e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (3.16e-1)" CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.4;Intestinal goblet cells: 155.5;Prostatic glandular cells: 101.8;Syncytiotrophoblasts: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 841.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" CARD19 "bA370F5.1, BinCARD, C9orf89, MGC11115" ENSG00000165233 "Caspase recruitment domain family member 19" Q96LW7 9 93096217-93113283 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Langerhans cells: 202.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010921, HPA010990, HPA038297" Approved Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 57: Platelets - Hemostasis" 1 Mitochondria "HPA010921: AB_10670295, HPA010990: AB_2668400, HPA038297: AB_2675938" "unprognostic (7.26e-2)" "unprognostic (1.15e-2)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (2.22e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.21e-1)" "unprognostic (1.36e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (9.13e-2)" "unprognostic (6.82e-2)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.5;Inhibitory neurons: 103.8;Oligodendrocyte precursor cells: 115.1;Oligodendrocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044404, HPA052908" Approved Approved Nucleoplasm Yes No "Cluster 24: Non-specific - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm "HPA044404: AB_10964353, HPA052908: " "unprognostic (4.02e-2)" "unprognostic (4.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (3.66e-2)" "unprognostic (2.18e-2)" "unprognostic (9.83e-2)" "unprognostic (4.74e-2)" "unprognostic (4.95e-3)" "unprognostic (2.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (1.93e-1)" "unprognostic (7.07e-2)" "unprognostic (2.59e-3)" CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923554 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 129.9;Oligodendrocyte precursor cells: 420.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 46.8" "Lineage enriched" "Detected in many" 10 "granulocytes: 46.8" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 76: Oligodendrocyte precursor - Unknown function" 9 Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183668-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "parathyroid gland: 633.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 47.7;Distal tubular cells: 6.1;Ductal cells: 5.3;Enteroendocrine cells: 11.8;Pancreatic endocrine cells: 17.0" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "thyroid cancer: 7.0" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039686, HPA050335" Enhanced NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" CATSPER4 ENSG00000188782 "Cation channel sperm associated 4" Q7RTX7 1 26190561-26202968 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "testis: 10.9" "Cell type enriched" "Detected in some" 8 "Early spermatids: 90.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045257 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 18: Early spermatids - Unknown function" 1 "HPA045257: AB_10968995" "unprognostic (7.20e-2)" "unprognostic (2.06e-2)" "unprognostic (4.56e-2)" "unprognostic (2.69e-2)" "unprognostic (3.49e-1)" "unprognostic (3.86e-2)" "unprognostic (1.52e-2)" "unprognostic (2.16e-1)" "unprognostic (3.06e-1)" "unprognostic (6.78e-2)" "unprognostic (6.98e-2)" "unprognostic (6.67e-5)" CATSPERB "C14orf161, FLJ14298" ENSG00000133962 "Cation channel sperm associated auxiliary subunit beta" Q9H7T0 14 91580696-91780707 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 10.4" "Cell type enhanced" "Detected in some" "Early spermatids: 31.8;Exocrine glandular cells: 22.5;Gastric mucus-secreting cells: 7.1;Mucus glandular cells: 6.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035134 Uncertain Vesicles NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA035134: AB_10671510" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (1.16e-3)" "unprognostic (1.93e-1)" "unprognostic (7.04e-3)" "unprognostic (2.72e-5)" "unprognostic (1.81e-1)" "unprognostic (5.01e-3)" "unprognostic (1.81e-3)" "unprognostic (3.52e-3)" "unprognostic (2.30e-2)" "unprognostic (4.34e-1)" "unprognostic (8.99e-3)" "unprognostic (6.85e-2)" "unprognostic (8.31e-2)" "unprognostic (8.88e-2)" "unprognostic (2.71e-3)" CATSPERD "MGC39581, TMEM146" ENSG00000174898 "Cation channel sperm associated auxiliary subunit delta" Q86XM0 19 5720637-5778734 "Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 8.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 112.6;Early spermatids: 80.5;Late spermatids: 177.7;Oocytes: 33.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA024056 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Ciliated cells - Cilium assembly" 3 "HPA024056: AB_1858093" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (3.77e-3)" "unprognostic (9.91e-2)" "unprognostic (3.74e-2)" "unprognostic (6.85e-2)" "unprognostic (2.63e-3)" "unprognostic (2.19e-2)" "unprognostic (5.18e-2)" "unprognostic (2.50e-1)" "unprognostic (5.95e-8)" "unprognostic (2.54e-2)" "unprognostic (9.92e-2)" "unprognostic (2.83e-1)" "unprognostic (3.74e-2)" CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 30.5" "Cell type enhanced" "Detected in many" "Early spermatids: 25.1;Gastric mucus-secreting cells: 22.4;Late spermatids: 47.2;Proximal enterocytes: 18.4;Spermatocytes: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2033.4;Alveolar cells type 1: 1340.0;Basal keratinocytes: 830.7;Endothelial cells: 1042.5;Lymphatic endothelial cells: 1303.0;Smooth muscle cells: 797.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 169.0" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 39: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 28 "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 219.3" "Cell type enhanced" "Detected in many" "Adipocytes: 286.6;Alveolar cells type 1: 672.1;Basal keratinocytes: 318.9;Basal respiratory cells: 313.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 433 "granulocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB013488: AB_2533493, HPA044810: AB_2679098" "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 176.3;tongue: 70.1" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 15.7;Skeletal myocytes: 57.6" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 81 "Sarcoma: 13.9" "Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017518, CAB018557, HPA054488, HPA072988" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" 2 "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504, HPA072988: " "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" CBARP "BARP, C19orf26, DOS, MGC40084" ENSG00000099625 "CACN subunit beta associated regulatory protein" Q8N350 19 1228287-1238027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.2;pituitary gland: 21.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.1;Early spermatids: 60.1;Horizontal cells: 16.4;Late spermatids: 86.6;Spermatocytes: 40.3" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012777 Approved Nucleoplasm NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Nucleoplasm "HPA012777: AB_2067005" "unprognostic (1.31e-1)" "unprognostic (4.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" "unprognostic (3.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.58e-2)" "unprognostic (2.86e-3)" "unprognostic (3.03e-1)" "unprognostic (5.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (7.42e-5)" CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" 6 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 85.4;retina: 50.9;testis: 180.5" "Group enriched" "Detected in many" 4 "Early spermatids: 736.4;Late spermatids: 1957.3" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.2" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050137 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 72.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 46.5;Cardiomyocytes: 161.5;Early spermatids: 27.7;granulocytes: 29.0;Lymphatic endothelial cells: 48.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.4" "Group enriched" "Detected in many" 9 "B-cells: 7.9;T-cells: 14.4" "Cancer enhanced" "Detected in some" "lymphoma: 3.0;Sarcoma: 2.3" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 30: Heart muscle - Heart development" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 7 Nucleoplasm "HPA012718: AB_2072055" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "unprognostic (8.62e-3)" "unprognostic (4.25e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.33e-2)" "unprognostic (8.03e-3)" "unprognostic (7.71e-8)" "unprognostic (2.50e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-1)" CCDC144A "FLJ43983, KIAA0565" ENSG00000170160 "Coiled-coil domain containing 144A" A2RUR9 17 16689537-16777881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.5" "Cell type enhanced" "Detected in many" "Early spermatids: 41.5;Spermatocytes: 102.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA022996, HPA023009, HPA047851, HPA066260" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Cytosol "Cell Junctions" "HPA022996: AB_1846136, HPA023009: AB_1846137, HPA047851: AB_2680182, HPA066260: " "unprognostic (8.54e-2)" "unprognostic (4.49e-3)" "unprognostic (1.07e-1)" "unprognostic (8.34e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-2)" "unprognostic (1.57e-1)" "unprognostic (5.69e-2)" "unprognostic (6.95e-2)" "unprognostic (2.60e-2)" "unprognostic (2.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (9.49e-2)" "unprognostic (3.32e-1)" "unprognostic (1.41e-1)" "unprognostic (1.74e-1)" CCDC167 "C6orf129, dJ153P14.2" ENSG00000198937 "Coiled-coil domain containing 167" Q9P0B6 6 37482938-37499893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 273.1;Oocytes: 178.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 145.9;granulocytes: 140.8;T-cells: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045215 Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 27: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 77: Plasma cells - Protein processing" 32 Cytosol "HPA045215: AB_10962866" "unprognostic (1.82e-1)" "prognostic favorable (7.59e-4)" "unprognostic (6.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.86e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (2.73e-1)" "unprognostic (7.67e-2)" "unprognostic (3.41e-3)" "unprognostic (2.71e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.71e-7)" "unprognostic (1.57e-1)" "unprognostic (4.06e-1)" "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" CCDC168 "C13orf40, FLJ40176" ENSG00000175820 "Coiled-coil domain containing 168" Q8NDH2 13 102729367-102759072 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 8.6" "Cell type enriched" "Detected in some" 5 "Early spermatids: 1166.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA048184, HPA058793, HPA078547" Uncertain Approved Nucleoli,Centrosome,Cytosol NA NA "Cluster 10: Testis - Spermatid development" "Cluster 53: Neurons - Mixed function" "Cluster 21: Early spermatids - Spermatogenesis" "Nucleoli, Centrosome" Cytosol "HPA048184: AB_2680303, HPA058793: AB_2683823, HPA078547: " "unprognostic (2.06e-1)" "unprognostic (7.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-4)" "unprognostic (2.09e-2)" "unprognostic (3.68e-2)" "unprognostic (2.74e-1)" "unprognostic (5.05e-2)" "unprognostic (3.61e-1)" "unprognostic (2.89e-3)" "unprognostic (1.73e-1)" "unprognostic (1.44e-5)" "unprognostic (2.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.85e-1)" "unprognostic (6.94e-2)" CCDC188 ENSG00000234409 "Coiled-coil domain containing 188" H7C350 22 20148416-20151055 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 39.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 988.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.4" "Prostate - Endothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049901 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" "Nuclear bodies" Nucleoplasm "HPA049901: AB_2680943" "unprognostic (9.83e-2)" "unprognostic (3.09e-2)" "unprognostic (9.79e-2)" "unprognostic (6.42e-3)" "unprognostic (2.45e-1)" "unprognostic (3.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.02e-1)" "unprognostic (8.43e-2)" "unprognostic (4.08e-3)" "unprognostic (1.67e-5)" "unprognostic (1.16e-1)" "unprognostic (5.37e-5)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-2)" CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 6 "Endoplasmic reticulum" "HPA029674: AB_10602703, HPA072573: AB_2686535, HPA075958: " "unprognostic (6.33e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.38e-1)" "unprognostic (3.54e-1)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (1.88e-1)" "unprognostic (6.43e-2)" "unprognostic (7.46e-2)" "unprognostic (1.16e-1)" CCDC51 FLJ12436 ENSG00000164051 "Coiled-coil domain containing 51" Q96ER9 3 48432164-48440456 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 62.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 43.4;Proximal tubular cells: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010980, HPA011408" Supported Supported Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 3 "Nucleoplasm, Mitochondria" Centrosome "HPA010980: AB_1846155, HPA011408: AB_2072212" "unprognostic (1.24e-2)" "unprognostic (5.23e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-1)" "unprognostic (2.75e-3)" "unprognostic (4.71e-3)" "unprognostic (1.26e-2)" "unprognostic (3.04e-1)" "unprognostic (3.26e-2)" "unprognostic (7.70e-2)" "unprognostic (1.47e-3)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" CCDC90B "MDS011, MDS025" ENSG00000137500 "Coiled-coil domain containing 90B" Q9GZT6 11 83259081-83286390 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 409.7;Late spermatids: 291.8;Spermatocytes: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011130, HPA011931" Supported Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Testis - Spermatid development" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 13: Spermatids - Transcription" 6 Mitochondria "HPA011130: AB_1846170, HPA011931: AB_2072332" "unprognostic (5.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.57e-3)" "unprognostic (5.76e-3)" "unprognostic (3.53e-2)" "unprognostic (6.01e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-2)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 28.2;stomach 1: 16.1" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.8" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Group enriched" "Detected in many" 5 "hypothalamus: 11.0;midbrain: 14.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 4.3;liver cancer: 2.0;Neuroblastoma: 7.5" "Stomach - Chief cells" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in many" "midbrain: 16.5" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Gastric mucus-secreting cells - Digestion" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (7.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-2)" "unprognostic (3.36e-1)" "unprognostic (3.79e-1)" CCKBR ENSG00000110148 "Cholecystokinin B receptor" P32239 11 6259806-6272127 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "brain: 20.8;pancreas: 26.2;stomach 1: 40.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 14.1;Gastric mucus-secreting cells: 15.3;Granulosa cells: 17.1;Inhibitory neurons: 3.9" "Cancer enriched" "Detected in some" 8 "testis cancer: 9.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 2.5;testis cancer: 9.7" "Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA079548 Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Vesicles "Plasma membrane" "HPA079548: " "unprognostic (2.82e-1)" "unprognostic (4.62e-2)" "unprognostic (1.79e-3)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (6.34e-4)" "unprognostic (8.01e-2)" "unprognostic (3.01e-2)" "unprognostic (9.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (1.30e-2)" CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.9;lymphoid tissue: 131.6" "Group enriched" "Detected in many" 10 "NK-cells: 2703.3;T-cells: 2071.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6781.0;memory CD8 T-cell: 7136.0" "Group enriched" "Detected in all" 7 "NK-cells: 2043.0;T-cells: 7136.0" "Cancer enhanced" "Detected in many" "Leukemia: 57.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" CAB078447 Enhanced "Secreted to blood" Chemokine NA NA 20100000 2900000 "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 25 "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 89.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 280.3;neutrophil: 298.2" "Group enriched" "Detected in all" 7 "granulocytes: 298.2;monocytes: 84.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: AB_2668242, HPA026861: AB_1846192" "unprognostic (3.14e-2)" "unprognostic (2.94e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-2)" "unprognostic (8.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-2)" "unprognostic (2.61e-2)" "prognostic unfavorable (5.07e-4)" "prognostic unfavorable (5.02e-5)" "unprognostic (1.15e-1)" "unprognostic (1.71e-2)" "unprognostic (1.72e-2)" CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.7" "Cell type enriched" "Detected in many" 6 "Plasma cells: 99.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.6" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.6" "Cancer enriched" "Detected in many" 4 "Myeloma: 42.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: AB_2680232, HPA069188: AB_2686100" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353864-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.8" "Group enriched" "Detected in some" 4 "dendritic cells: 60.6;Kupffer cells: 47.0;Langerhans cells: 16.5;Macrophages: 21.7;Plasma cells: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 557.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 29.9" "Breast - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46130890-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.5;skeletal muscle: 1.7" "Cell type enriched" "Detected in some" 8 "Oocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3400.3;eosinophil: 2516.4" "Lineage enriched" "Detected in many" 109 "granulocytes: 3400.3" "Cancer enriched" "Detected in single" 4 "Myeloma: 3.2" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Neutrophils - Degranulation" "Plasma membrane" "CAB003795: AB_562259, HPA069514: " "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.6;urinary bladder: 5.2" "Cell type enriched" "Detected in some" 5 "T-cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.8" "Lineage enriched" "Detected in many" 41 "T-cells: 60.8" "Cancer enriched" "Detected in some" 4 "lymphoma: 18.7" "Adipose subcutaneous - T-cells, Breast - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139141 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 6 "B-cells: 15.7;T-cells: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "MAIT T-cell: 70.3;memory B-cell: 64.1;memory CD4 T-cell: 27.4;naive B-cell: 73.4;T-reg: 52.1" "Group enriched" "Detected in many" 5 "B-cells: 73.4;T-cells: 70.3" "Cancer enhanced" "Detected in some" "liver cancer: 5.2" "Adipose subcutaneous - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Not detected" "Not detected" "CAB006820, HPA014488" Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 7: T-cells - T-cell receptor" "CAB006820: , HPA014488: AB_1846639" "unprognostic (1.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.07e-3)" "unprognostic (2.08e-1)" "unprognostic (8.43e-2)" "unprognostic (2.05e-4)" "unprognostic (2.39e-1)" "unprognostic (4.98e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-4)" "unprognostic (3.74e-2)" "unprognostic (7.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;lymphoid tissue: 82.0" "Cell type enhanced" "Detected in some" "B-cells: 167.8;Cytotrophoblasts: 150.8;Langerhans cells: 549.3;Syncytiotrophoblasts: 515.0;T-cells: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4611.8" "Lineage enriched" "Detected in all" 4 "T-cells: 4611.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 140.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 11: White matter - Signal transduction" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Langerhans cells - Innate immune response" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" CCR8 "CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1" ENSG00000179934 "C-C motif chemokine receptor 8" P51685 3 39329709-39333680 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 7.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "T-reg: 25.8" "Lineage enriched" "Detected in single" 32 "T-cells: 25.8" "Group enriched" "Detected in some" 8 "Leukemia: 2.9;lymphoma: 4.4;testis cancer: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA042383 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA042383: AB_2732497" "unprognostic (2.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.38e-2)" "unprognostic (7.63e-4)" "unprognostic (3.31e-1)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (3.37e-2)" "unprognostic (7.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.65e-8)" "unprognostic (7.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.56e-1)" "unprognostic (4.14e-1)" CCR9 "CDw199, GPR-9-6, GPR28" ENSG00000173585 "C-C motif chemokine receptor 9" P51686 3 45884425-45903174 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 126.5" "Group enriched" "Detected in some" 5 "B-cells: 1.2;T-cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "memory B-cell: 24.3;naive B-cell: 15.7;T-reg: 8.2" "Group enriched" "Detected in many" 43 "B-cells: 24.3;T-cells: 8.2" "Cancer enriched" "Detected in single" 8 "Leukemia: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006839, HPA066879" Uncertain Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "Endoplasmic reticulum" "CAB006839: , HPA066879: " "unprognostic (3.08e-3)" "unprognostic (3.37e-1)" "unprognostic (5.56e-2)" "unprognostic (1.78e-1)" "unprognostic (8.65e-3)" "unprognostic (7.88e-3)" "unprognostic (4.54e-1)" "unprognostic (2.94e-2)" "unprognostic (3.00e-1)" "unprognostic (1.77e-1)" "unprognostic (8.06e-2)" "unprognostic (1.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.88e-1)" "unprognostic (4.34e-1)" "unprognostic (2.27e-1)" "unprognostic (7.20e-3)" CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.3;Hofbauer cells: 49.8;Langerhans cells: 44.8;Macrophages: 61.6;monocytes: 179.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043238 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" CD101 "IGSF2, V7" ENSG00000134256 "CD101 molecule" Q93033 1 117001750-117036552 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;intestine: 6.1;lung: 6.5" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.9;Langerhans cells: 4.7;Macrophages: 7.8;monocytes: 24.7;T-cells: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "eosinophil: 97.1" "Group enriched" "Detected in many" 18 "dendritic cells: 33.8;granulocytes: 97.1;monocytes: 53.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049527, HPA057763" Approved Uncertain Mitochondria NA NA 630000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" Mitochondria "HPA049527: , HPA057763: AB_2683519" "unprognostic (1.25e-1)" "unprognostic (7.95e-3)" "unprognostic (5.40e-3)" "unprognostic (4.10e-3)" "unprognostic (2.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.58e-3)" "unprognostic (3.57e-2)" "unprognostic (7.29e-3)" "unprognostic (3.15e-1)" "unprognostic (4.54e-2)" "unprognostic (7.15e-6)" "unprognostic (7.00e-2)" "unprognostic (8.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.28e-2)" CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 319.7" "Cell type enhanced" "Detected in many" "Adipocytes: 63.9;Basal keratinocytes: 40.5;Basal respiratory cells: 56.5;Basal squamous epithelial cells: 51.2;Squamous epithelial cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Prostate - Endothelial cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 234.7" "Group enriched" "Detected in many" 4 "Kupffer cells: 1630.5;Macrophages: 624.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 112.0" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.3" "Group enriched" "Detected in many" 40 "dendritic cells: 65.3;monocytes: 76.1" "Cancer enriched" "Detected in single" 9 "lymphoma: 6.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" "Acute phase" NA NA 903000000 1600000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" CD163L1 "CD163B, M160, SCARI2, WC1" ENSG00000177675 "CD163 molecule like 1" Q9NR16 12 7346685-7479897 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 31.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 28.5;Breast myoepithelial cells: 17.9;Excitatory neurons: 18.2;Inhibitory neurons: 15.9;Lymphatic endothelial cells: 13.8;Melanocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Macrophages, Testis - Early spermatids" HPA015663 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" "No annotated function" NA NA 660000 "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Breast glandular cells - Lactation" "Centrosome, Cytosol" Nucleoplasm "HPA015663: AB_2072575" "unprognostic (1.25e-3)" "unprognostic (1.77e-1)" "unprognostic (1.42e-2)" "unprognostic (7.46e-3)" "unprognostic (2.29e-2)" "unprognostic (7.79e-2)" "unprognostic (9.39e-2)" "unprognostic (4.44e-3)" "unprognostic (1.07e-1)" "unprognostic (8.35e-2)" "unprognostic (1.08e-1)" "unprognostic (3.08e-1)" "unprognostic (1.26e-6)" "unprognostic (8.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-1)" CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 751.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 3 "HPA010636: AB_1078447" "unprognostic (1.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.89e-2)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (1.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (1.38e-1)" "unprognostic (7.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (1.51e-1)" CD164L2 ENSG00000174950 "CD164 molecule like 2" Q6UWJ8 1 27379176-27383333 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.4;fallopian tube: 29.0;salivary gland: 13.1" "Cell type enriched" "Detected in some" 4 "Ciliated cells: 121.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "thalamus: 2.6" HPA062915 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "Plasma membrane" "HPA062915: AB_2684903" "unprognostic (8.97e-3)" "unprognostic (2.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "prognostic favorable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (4.47e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (4.07e-2)" "unprognostic (5.91e-6)" "unprognostic (1.33e-2)" "unprognostic (6.42e-2)" "unprognostic (1.34e-2)" "unprognostic (2.71e-2)" CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.7" "Cell type enhanced" "Detected in some" "B-cells: 55.8;Hofbauer cells: 68.8;Kupffer cells: 22.8;Macrophages: 19.6;Plasma cells: 52.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.2;naive B-cell: 79.2" "Group enriched" "Detected in many" 25 "B-cells: 79.2;dendritic cells: 23.5;monocytes: 34.7" "Group enriched" "Detected in some" 4 "lymphoma: 19.2;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Plasma cells, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 1 "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" CD19 ENSG00000177455 "CD19 molecule" P15391 16 28931965-28939342 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 32.1;lymphoid tissue: 73.1" "Cell type enhanced" "Detected in some" "B-cells: 128.5;Early spermatids: 52.8;Plasma cells: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 81 "memory B-cell: 138.6;naive B-cell: 172.5" "Lineage enriched" "Detected in many" 90 "B-cells: 172.5" "Group enriched" "Detected in some" 13 "Leukemia: 37.8;lymphoma: 71.1" "Liver - T-cells, Lung - B-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB016110 Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" "CAB016110: AB_626952" "unprognostic (3.27e-3)" "unprognostic (1.19e-3)" "unprognostic (6.63e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-3)" "unprognostic (3.11e-5)" "unprognostic (2.61e-1)" "unprognostic (6.96e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-6)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" CD1A CD1 ENSG00000158477 "CD1a molecule" P06126 1 158254424-158258269 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 309.8" "Cell type enriched" "Detected in some" 15 "Langerhans cells: 204.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "classical monocyte: 6.4;intermediate monocyte: 4.2;memory B-cell: 10.2;myeloid DC: 11.4;naive B-cell: 5.3" "Group enriched" "Detected in many" 37 "B-cells: 10.2;dendritic cells: 11.4;monocytes: 6.4" "Cancer enriched" "Detected in single" 16 "Leukemia: 13.5" "Not detected" "Not detected" "CAB000009, HPA010734" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" 1 "CAB000009: AB_2073290, HPA010734: AB_1078452" "unprognostic (7.21e-5)" "prognostic favorable (6.37e-4)" "unprognostic (1.37e-5)" "unprognostic (2.55e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-2)" "unprognostic (9.93e-4)" "unprognostic (1.49e-2)" "unprognostic (3.12e-1)" "unprognostic (3.86e-2)" "unprognostic (6.99e-2)" "unprognostic (5.12e-2)" "unprognostic (5.49e-5)" "unprognostic (5.58e-2)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (8.81e-2)" CD1B CD1 ENSG00000158485 "CD1b molecule" P29016 1 158327951-158331531 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 157 "lymphoid tissue: 515.3" "Cell type enriched" "Detected in some" 35 "Langerhans cells: 200.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "myeloid DC: 19.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 19.2" "Cancer enriched" "Detected in single" 487 "Leukemia: 48.7" "Low region specificity" "Detected in all" HPA021824 Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Golgi apparatus, Vesicles" Cytosol "HPA021824: AB_1846262" "unprognostic (7.72e-3)" "unprognostic (1.55e-4)" "unprognostic (1.66e-5)" "unprognostic (1.04e-2)" "unprognostic (1.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.89e-4)" "unprognostic (2.27e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (9.53e-2)" "unprognostic (3.23e-1)" "unprognostic (3.52e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (3.53e-2)" CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 126.9" "Cell type enriched" "Detected in some" 9 "Langerhans cells: 743.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.5;myeloid DC: 325.4" "Group enriched" "Detected in many" 8 "B-cells: 84.5;dendritic cells: 325.4" "Group enriched" "Detected in some" 46 "Leukemia: 5.3;lymphoma: 7.2" "Liver - T-cells, Skin - Langerhans cells, Thyroid - T-cells" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" 2 "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 17.7;liver: 15.0;lymphoid tissue: 23.4" "Cell type enhanced" "Detected in some" "B-cells: 20.3;Hofbauer cells: 30.4;Kupffer cells: 50.2;Macrophages: 33.8;monocytes: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "classical monocyte: 139.1;intermediate monocyte: 63.8;myeloid DC: 139.4" "Group enriched" "Detected in many" 8 "dendritic cells: 139.4;monocytes: 139.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.3;lymphoma: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "lymphoid tissue: 937.7" "Cell type enriched" "Detected in some" 19 "Langerhans cells: 750.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.6" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.6" "Cancer enriched" "Detected in single" 433 "Leukemia: 66.8" "Skin - Langerhans cells" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" Immunity NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" "Golgi apparatus" Nucleoli "HPA057769: AB_2683522, HPA070634: " "unprognostic (7.94e-3)" "unprognostic (1.85e-5)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "unprognostic (1.54e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (8.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (8.50e-2)" "unprognostic (2.45e-1)" CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 243.3" "Group enriched" "Detected in many" 11 "NK-cells: 199.5;T-cells: 483.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 422.7;MAIT T-cell: 403.9;memory CD4 T-cell: 611.9;memory CD8 T-cell: 713.9;naive CD4 T-cell: 317.2;naive CD8 T-cell: 487.5;NK-cell: 1110.8;T-reg: 656.9" "Group enriched" "Detected in all" 10 "NK-cells: 1110.8;T-cells: 713.9" "Group enriched" "Detected in some" 66 "Leukemia: 11.8;lymphoma: 12.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.6;Inhibitory neurons: 53.2;Lymphatic endothelial cells: 79.1;Mesothelial cells: 88.0;Syncytiotrophoblasts: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.8;naive B-cell: 83.8" "Lineage enriched" "Detected in many" 23 "B-cells: 83.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 21.0;skin cancer: 31.2" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 34: B-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.6;granulocytes: 24.1;Hofbauer cells: 29.6;Langerhans cells: 23.3;Macrophages: 9.0;T-cells: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 4 "basophil: 235.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 235.9" "Cancer enhanced" "Detected in some" "cervical cancer: 10.0" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 2000000 "Cluster 46: Basophils - Proteolysis" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 85.4" "Group enriched" "Detected in some" 4 "Langerhans cells: 15.1;Macrophages: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cancer enhanced" "Detected in some" "Bone cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 13: Skin - Cornification" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Dendritic cells - Antigen presentation" 5 Cytosol "CAB002222: AB_563850, HPA011216: AB_1078453" "unprognostic (1.45e-2)" "unprognostic (8.28e-3)" "unprognostic (9.34e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.63e-1)" "unprognostic (7.92e-4)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, hDC-SIGN" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.0;placenta: 22.0" "Group enriched" "Detected in some" 4 "Kupffer cells: 12.9;Langerhans cells: 14.9;Macrophages: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 5 "dendritic cells: 1.2;monocytes: 1.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "CAB032436, CAB033831" Supported "Intracellular and membrane" Receptor NA NA 3100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" CD22 "SIGLEC-2, SIGLEC2" ENSG00000012124 "CD22 molecule" P20273 19 35319261-35347361 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 223.3;ovary: 123.5" "Cell type enhanced" "Detected in many" "B-cells: 155.6;granulocytes: 71.4;Granulosa cells: 52.3;Oligodendrocytes: 85.2;Ovarian stromal cells: 46.7;Secretory cells: 34.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 24 "memory B-cell: 97.9;naive B-cell: 120.7" "Lineage enriched" "Detected in many" 26 "B-cells: 120.7" "Group enriched" "Detected in many" 9 "Leukemia: 48.4;lymphoma: 193.5" "Colon - Mast cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002418, HPA024353, HPA066523" Enhanced NA NA 13000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 4 "CAB002418: AB_563529, HPA024353: AB_10600695, HPA066523: " "unprognostic (2.80e-3)" "unprognostic (3.99e-2)" "unprognostic (6.79e-3)" "unprognostic (9.17e-2)" "unprognostic (3.07e-1)" "unprognostic (6.45e-3)" "unprognostic (3.79e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.47e-1)" "unprognostic (1.75e-3)" "unprognostic (1.98e-2)" "unprognostic (1.48e-2)" "unprognostic (9.05e-2)" "unprognostic (3.04e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "lymphoid tissue: 19.7;parathyroid gland: 60.5" "Cell type enhanced" "Detected in many" "Microglial cells: 21.5;NK-cells: 101.6;Oligodendrocytes: 24.7;Schwann cells: 29.5;T-cells: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 36.7;MAIT T-cell: 13.4;memory CD4 T-cell: 28.9;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.4;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.7" "Group enriched" "Detected in some" 6 "Leukemia: 8.2;lymphoma: 10.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 15: NK-cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" CD247 "CD3-ZETA, CD3H, CD3Q, CD3Z, CD3ZETA, TCRZ" ENSG00000198821 "CD247 molecule" P20963 1 167425027-167518640 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 39.7;lymphoid tissue: 157.1" "Group enriched" "Detected in many" 22 "NK-cells: 775.2;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 20 "gdT-cell: 336.7;MAIT T-cell: 189.2;memory CD4 T-cell: 181.3;memory CD8 T-cell: 205.8;naive CD4 T-cell: 227.8;naive CD8 T-cell: 184.5;NK-cell: 213.0;T-reg: 242.5" "Group enriched" "Detected in all" 25 "NK-cells: 213.0;T-cells: 336.7" "Group enriched" "Detected in some" 11 "Leukemia: 23.4;lymphoma: 21.4;Myeloma: 16.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 27: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 5 "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 229.8;breast: 150.5" "Group enriched" "Detected in many" 5 "Endometrial stromal cells: 157.0;Fibroblasts: 195.1;Leydig cells: 75.3;Mesothelial cells: 52.3;Smooth muscle cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.9" "Lineage enriched" "Detected in single" 145 "T-cells: 21.9" "Group enriched" "Detected in many" 6 "Bone cancer: 137.0;Neuroblastoma: 39.8;Sarcoma: 67.1" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051856 Enhanced Approved "Plasma membrane" NA NA 43000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 4 "Plasma membrane" "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" CD27 "S152, TNFRSF7, Tp55" ENSG00000139193 "CD27 molecule" P26842 12 6444955-6451718 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 144.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 455.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 642.1" "Group enriched" "Detected in all" 7 "B-cells: 294.3;T-cells: 642.1" "Cancer enriched" "Detected in some" 7 "lymphoma: 88.8" "Adipose subcutaneous - T-cells, Breast - Plasma cells, Lung - Plasma cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002420, HPA038936, HPA069501, CAB080304" Enhanced Approved Vesicles NA NA 100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" 4 Vesicles "CAB002420: AB_563539, CAB080304: , HPA038936: AB_2676278, HPA069501: " "unprognostic (2.75e-3)" "prognostic favorable (3.77e-5)" "unprognostic (8.87e-3)" "prognostic favorable (2.90e-4)" "unprognostic (2.35e-1)" "prognostic favorable (6.65e-7)" "unprognostic (3.56e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.50e-4)" "unprognostic (1.31e-3)" "unprognostic (4.32e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.80e-1)" "unprognostic (3.15e-1)" "unprognostic (1.28e-1)" "unprognostic (7.35e-2)" CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.3" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 31.3;granulocytes: 43.8;Langerhans cells: 62.7;Syncytiotrophoblasts: 54.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 14: Langerhans cells - Innate immune response" 5 "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 242.7;Hofbauer cells: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 4: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 29.9;placenta: 14.3" "Group enriched" "Detected in some" 10 "Hofbauer cells: 31.1;T-cells: 60.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 102.2" "Lineage enriched" "Detected in many" 7 "T-cells: 102.2" "Cancer enriched" "Detected in some" 13 "Myeloma: 98.6" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Skin - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Low region specificity" "Detected in all" HPA070003 Enhanced NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 92.9" "Cell type enhanced" "Detected in some" "dendritic cells: 55.9;Hofbauer cells: 135.8;Kupffer cells: 95.5;Macrophages: 76.0;monocytes: 132.3;NK-cells: 138.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 40.9;Myeloma: 12.0" "Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - T-cells" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" 6 "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;lung: 8.1;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.5;Kupffer cells: 17.8;Langerhans cells: 16.1;Macrophages: 28.0;monocytes: 31.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.5;non-classical monocyte: 243.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Leukemia: 5.2;lymphoma: 5.0;thyroid cancer: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 7 "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" CD300E "CD300LE, CLM2, IREM2" ENSG00000186407 "CD300e molecule" Q496F6 17 74609885-74623738 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 50.0;Kupffer cells: 73.0;Macrophages: 103.8;monocytes: 291.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 87.9;intermediate monocyte: 135.0;non-classical monocyte: 149.1" "Lineage enriched" "Detected in many" 7 "monocytes: 149.1" "Not detected" "Not detected" "Colon - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA015570 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 3 "HPA015570: AB_1846294" "unprognostic (1.70e-1)" "unprognostic (6.82e-2)" "unprognostic (1.76e-1)" "unprognostic (2.63e-2)" "unprognostic (1.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.68e-2)" "unprognostic (7.80e-3)" "unprognostic (4.51e-1)" "unprognostic (1.53e-1)" "unprognostic (2.69e-2)" "unprognostic (5.15e-2)" "unprognostic (4.19e-7)" "unprognostic (1.90e-2)" "unprognostic (2.00e-4)" "unprognostic (7.38e-3)" "unprognostic (1.19e-1)" CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.6;lymphoid tissue: 8.0" "Cell type enhanced" "Detected in some" "dendritic cells: 14.7;Hofbauer cells: 13.1;Kupffer cells: 11.8;Langerhans cells: 9.4;Macrophages: 18.7;monocytes: 4.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 34.0" "Immune cell enhanced" "Detected in many" "eosinophil: 76.1" "Group enriched" "Detected in many" 53 "dendritic cells: 25.1;granulocytes: 76.1;monocytes: 31.7" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.8" "Adipose visceral - Macrophages, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060449 Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 5 "Plasma membrane" "HPA060449: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (3.32e-1)" "unprognostic (2.49e-4)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (7.08e-2)" "unprognostic (4.01e-2)" CD300LD "CD300D, CMRF35A4" ENSG00000204345 "CD300 molecule like family member d" Q6UXZ3 17 74579365-74592283 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 5.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.1" "Not detected" "Not detected" "Testis - Late spermatids" HPA027756 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA027756: AB_10601097" "unprognostic (8.03e-2)" "unprognostic (3.30e-1)" CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 26.7;lung: 17.1;lymphoid tissue: 28.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 41.0;Kupffer cells: 27.4;Macrophages: 37.8;monocytes: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 234.8" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.8;monocytes: 193.8" "Cancer enriched" "Detected in single" 78 "Leukemia: 19.2" "Lung - Macrophages" HPA013712 Supported NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "HPA013712: AB_2668874" "unprognostic (6.51e-2)" "unprognostic (1.49e-3)" "unprognostic (3.81e-2)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (9.60e-2)" "unprognostic (4.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.79e-2)" CD320 "8D6, 8D6A, TCblR" ENSG00000167775 "CD320 molecule" Q9NPF0 19 8302127-8308358 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 411.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014500, HPA073489" Approved Approved Cytosol NA NA 61000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Cytosol "HPA014500: AB_1846295, HPA073489: AB_2686609" "unprognostic (9.97e-2)" "unprognostic (2.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.54e-3)" "unprognostic (2.17e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (4.02e-4)" "unprognostic (4.19e-2)" "unprognostic (7.13e-2)" "unprognostic (1.31e-1)" "unprognostic (9.35e-3)" "unprognostic (1.25e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (8.92e-2)" "unprognostic (3.14e-1)" "unprognostic (9.90e-2)" CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 23.4" "Group enriched" "Detected in some" 6 "granulocytes: 78.7;Hofbauer cells: 90.4;Kupffer cells: 95.7;Langerhans cells: 50.2;Macrophages: 55.2;monocytes: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.7;intermediate monocyte: 122.1;myeloid DC: 213.7;non-classical monocyte: 58.0" "Group enriched" "Detected in many" 9 "dendritic cells: 213.7;monocytes: 166.7" "Cancer enriched" "Detected in many" 8 "Leukemia: 53.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB011442, HPA035832, HPA064807, CAB079996, CAB080305" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 19 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB011442: , CAB079996: , CAB080305: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 297.5;Endothelial cells: 252.1;Fibroblasts: 121.6;Leydig cells: 141.8;Mesothelial cells: 167.7;Peritubular cells: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Leukemia: 63.7;Rhabdoid: 115.9;Sarcoma: 87.6" "Breast - Fibroblasts, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Lipid transport, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1480.0" "Group enriched" "Detected in many" 4 "Adipocytes: 2837.3;Cardiomyocytes: 872.7;Hofbauer cells: 1253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 965.2;intermediate monocyte: 271.3;myeloid DC: 507.9" "Group enriched" "Detected in all" 46 "dendritic cells: 507.9;monocytes: 965.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 153.6;intestine: 113.2;lymphoid tissue: 230.0" "Cell type enhanced" "Detected in many" "B-cells: 1676.3;dendritic cells: 531.6;granulocytes: 571.4;Hofbauer cells: 478.9;Langerhans cells: 410.3;monocytes: 820.9;NK-cells: 377.0;T-cells: 380.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 77.0;lymphoma: 248.0" "Breast - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 8 "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" CD3D "CD3-DELTA, CD3DELTA, T3D" ENSG00000167286 "CD3 delta subunit of T-cell receptor complex" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "lymphoid tissue: 846.9" "Cell type enriched" "Detected in many" 6 "T-cells: 663.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 53 "gdT-cell: 1434.7;MAIT T-cell: 971.2;memory CD4 T-cell: 1184.7;memory CD8 T-cell: 1338.7;naive CD4 T-cell: 1071.7;naive CD8 T-cell: 1320.2;T-reg: 1629.7" "Lineage enriched" "Detected in all" 68 "T-cells: 1629.7" "Cancer enriched" "Detected in some" 8 "Leukemia: 223.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" CD3E "CD3-epsilon, CD3epsilon" ENSG00000198851 "CD3 epsilon subunit of T-cell receptor complex" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 623.6" "Group enriched" "Detected in many" 18 "NK-cells: 214.7;T-cells: 646.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 491.6;MAIT T-cell: 421.5;memory CD4 T-cell: 415.6;memory CD8 T-cell: 463.4;naive CD4 T-cell: 493.3;naive CD8 T-cell: 502.8;NK-cell: 203.3;T-reg: 427.4" "Group enriched" "Detected in all" 21 "NK-cells: 203.3;T-cells: 502.8" "Cancer enriched" "Detected in some" 8 "Leukemia: 125.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 6 "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" CD3G "CD3-GAMMA, CD3GAMMA" ENSG00000160654 "CD3 gamma subunit of T-cell receptor complex" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 92.2" "Group enriched" "Detected in many" 14 "NK-cells: 95.2;T-cells: 331.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "gdT-cell: 228.7;MAIT T-cell: 135.3;memory CD4 T-cell: 187.4;memory CD8 T-cell: 196.4;naive CD4 T-cell: 192.7;naive CD8 T-cell: 241.8;T-reg: 200.1" "Lineage enriched" "Detected in many" 26 "T-cells: 241.8" "Cancer enriched" "Detected in some" 6 "Leukemia: 19.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 7 "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.3;lymphoid tissue: 213.7;parathyroid gland: 168.4" "Cell type enhanced" "Detected in many" "dendritic cells: 227.5;Hofbauer cells: 152.0;Kupffer cells: 190.2;Langerhans cells: 99.7;Macrophages: 116.7;monocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.4;intermediate monocyte: 241.4;memory CD4 T-cell: 153.8;myeloid DC: 166.4;naive CD4 T-cell: 128.5;non-classical monocyte: 205.2;plasmacytoid DC: 264.3;T-reg: 154.9" "Group enriched" "Detected in many" 20 "dendritic cells: 264.3;monocytes: 247.4;T-cells: 154.9" "Group enriched" "Detected in some" 35 "Leukemia: 40.6;lymphoma: 27.6;Myeloma: 23.9" "Colon - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "CAB000011: AB_442062, CAB068180: AB_2665653, HPA004252: AB_1078466, HPA004472: AB_1078465" "unprognostic (1.39e-2)" "unprognostic (1.12e-2)" "unprognostic (2.75e-2)" "prognostic favorable (2.16e-4)" "unprognostic (7.76e-2)" "unprognostic (4.82e-3)" "unprognostic (3.70e-2)" "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.06e-1)" "unprognostic (4.65e-3)" "unprognostic (9.08e-3)" "unprognostic (2.95e-1)" CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118271-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 126.2;Basal respiratory cells: 118.9;Langerhans cells: 237.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 108.3;naive B-cell: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 123.7;monocytes: 34.9" "Cancer enhanced" "Detected in many" "lymphoma: 97.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868" Enhanced "Secreted to blood" Receptor NA NA 705000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 18 "CAB002495: AB_563562, CAB072868: AB_2665719, HPA031567: AB_2673936, HPA031568: AB_2673937" "unprognostic (6.41e-2)" "unprognostic (1.55e-2)" "unprognostic (7.08e-3)" "unprognostic (6.21e-2)" "unprognostic (4.23e-3)" "unprognostic (1.25e-1)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (7.16e-2)" "unprognostic (2.48e-2)" "unprognostic (7.04e-2)" "prognostic unfavorable (4.48e-4)" "unprognostic (1.22e-1)" "unprognostic (4.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.28e-2)" CD40LG "CD154, CD40-L, CD40L, gp39, hCD40L, HIGM1, IMD3, T-BAM, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 3.7;lymphoid tissue: 14.7" "Cell type enriched" "Detected in some" 9 "T-cells: 78.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "gdT-cell: 26.4;MAIT T-cell: 64.4;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.3" "Lineage enriched" "Detected in many" 34 "T-cells: 80.5" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Cytokine NA NA 776000 20000 "Cluster 11: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 484.4" "Cell type enhanced" "Detected in many" "Ductal cells: 983.9;Exocrine glandular cells: 928.7;granulocytes: 1083.6;Langerhans cells: 2343.8;monocytes: 1059.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1400.7" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 1200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 3 "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752037-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 301.2;eosinophil: 387.4;neutrophil: 404.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 404.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 74: Neutrophils - Degranulation" 2 "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 484.0;Ductal cells: 550.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 146.6;lymphoid tissue: 277.0" "Cell type enhanced" "Detected in many" "B-cells: 357.1;granulocytes: 236.4;Hofbauer cells: 222.8;Kupffer cells: 212.1;Macrophages: 183.5;monocytes: 953.3;NK-cells: 402.1;Schwann cells: 198.4;T-cells: 432.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 243.2;Myeloma: 458.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Secreted to blood" "No annotated function" NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 1 "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 45.2" "Cell type enriched" "Detected in some" 4 "T-cells: 57.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 138.6" "Lineage enriched" "Detected in many" 33 "T-cells: 138.6" "Group enriched" "Detected in some" 7 "Leukemia: 17.3;lymphoma: 23.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 436.0" "Cell type enhanced" "Detected in many" "B-cells: 329.4;dendritic cells: 235.5;Hofbauer cells: 390.5;Kupffer cells: 363.7;Langerhans cells: 201.1;Macrophages: 287.4;monocytes: 537.9;NK-cells: 424.4;T-cells: 289.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 49 "Leukemia: 176.0;lymphoma: 278.2;Myeloma: 139.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 57 "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321519-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1446.0;monocytes: 1765.3;Syncytiotrophoblasts: 871.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 653.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" "Complement pathway" NA No 32300000 360000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "CAB010454: AB_2075970, HPA002190: AB_1078472, HPA024386: AB_1846319" "unprognostic (4.08e-2)" "unprognostic (3.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (3.41e-2)" "unprognostic (2.04e-1)" "unprognostic (9.70e-2)" "unprognostic (2.33e-2)" CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1341.1;Melanocytes: 1613.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 58000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lymphoid tissue: 42.2" "Group enriched" "Detected in some" 8 "NK-cells: 40.2;T-cells: 99.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 33 "gdT-cell: 27.8;MAIT T-cell: 24.7;memory CD4 T-cell: 51.5;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.5;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 50 "T-cells: 51.5" "Group enriched" "Detected in some" 10 "Leukemia: 10.8;lymphoma: 11.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" Immunity NA NA 5270000 160000 "Cluster 11: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1861.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" Transport NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" CD68 "DKFZp686M18236, GP110, LAMP4, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 346.5;lymphoid tissue: 360.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 223.6;Kupffer cells: 258.2;Langerhans cells: 80.9;Macrophages: 190.0;Proximal enterocytes: 193.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3264.9;intermediate monocyte: 3664.2;non-classical monocyte: 3764.8" "Group enriched" "Detected in all" 11 "dendritic cells: 1382.0;monocytes: 3764.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 7 "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" CD69 CLEC2C ENSG00000110848 "CD69 molecule" Q07108 12 9752486-9760901 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 167.0;lymphoid tissue: 92.1" "Cell type enhanced" "Detected in many" "B-cells: 934.4;granulocytes: 2458.1;NK-cells: 508.7;T-cells: 1192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 26.8;T-cells: 30.8" "Group enriched" "Detected in some" 6 "Leukemia: 45.9;lymphoma: 25.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002503, HPA050525" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 30: Granulocytes - Unknown function" 13 "CAB002503: AB_563625, HPA050525: AB_2681157" "prognostic favorable (3.31e-5)" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-3)" "unprognostic (4.76e-3)" "unprognostic (9.53e-3)" "unprognostic (9.73e-3)" "unprognostic (1.64e-2)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.88e-2)" "unprognostic (3.32e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;lymphoid tissue: 52.4" "Group enriched" "Detected in many" 14 "NK-cells: 1153.0;T-cells: 557.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 232.4" "Group enriched" "Detected in many" 22 "NK-cells: 232.4;T-cells: 71.8" "Group enriched" "Detected in some" 6 "Leukemia: 50.4;liver cancer: 16.7;Myeloma: 21.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" CD70 "CD27L, CD27LG, TNFSF7" ENSG00000125726 "CD70 molecule" P32970 19 6583183-6604103 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.3" "Cell type enhanced" "Detected in some" "B-cells: 46.4;Basal respiratory cells: 9.5;Fibroblasts: 7.9;Langerhans cells: 15.7;Plasma cells: 19.3;T-cells: 14.9" "Cancer enriched" "Detected in many" 4 "renal cancer: 24.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 44.3" "Group enriched" "Detected in many" 35 "B-cells: 24.3;T-cells: 44.3" "Cancer enhanced" "Detected in many" "Kidney cancer: 386.8" "Thyroid - T-cells" "Region enriched" "Detected in single" 25 "cerebellum: 11.3" "Low region specificity" "Detected in many" HPA046582 Uncertain Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Langerhans cells - Innate immune response" 1 Nucleoplasm "HPA046582: " "unprognostic (8.71e-2)" "unprognostic (9.91e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-4)" "unprognostic (1.73e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.57e-2)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609982-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 63.1" "Cell type enhanced" "Detected in many" "B-cells: 80.8;dendritic cells: 17.1;Hofbauer cells: 18.0;Kupffer cells: 19.2;Langerhans cells: 16.8;Macrophages: 18.6;monocytes: 26.2;NK-cells: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 233.6;naive B-cell: 413.2" "Lineage enriched" "Detected in all" 20 "B-cells: 413.2" "Group enriched" "Detected in some" 32 "Leukemia: 20.9;lymphoma: 39.1" "Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in some" "CAB002505, HPA044658" Enhanced Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 73: B-cells - B-cell function" 13 "Nucleoplasm, Mitochondria" "CAB002505: AB_563629, HPA044658: AB_2679039" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (7.81e-2)" "unprognostic (7.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (2.49e-8)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.59e-2)" CD74 "CLIP, DHLAG" ENSG00000019582 "CD74 molecule" P04233 5 150401637-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5112.2" "Cell type enhanced" "Detected in many" "B-cells: 11727.2;dendritic cells: 8645.4;Hofbauer cells: 5396.5;Langerhans cells: 26767.6;Macrophages: 7008.6;Proximal enterocytes: 5477.7;Schwann cells: 10143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11129.6;intermediate monocyte: 16174.8;memory B-cell: 27121.2;myeloid DC: 23965.9;naive B-cell: 28192.5;non-classical monocyte: 8146.1;plasmacytoid DC: 17015.9" "Group enriched" "Detected in all" 6 "B-cells: 28192.5;dendritic cells: 23965.9;monocytes: 16174.8" "Group enriched" "Detected in many" 7 "Leukemia: 998.7;lymphoma: 3214.7;Myeloma: 1807.4;skin cancer: 961.7" "Adipose visceral - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 7 "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" CD79A "Ig-alpha, IGA, IGAlpha, MB-1, MB1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 148.2;lymphoid tissue: 529.7" "Group enriched" "Detected in some" 29 "B-cells: 1202.8;Plasma cells: 778.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 38 "memory B-cell: 1278.3;naive B-cell: 1462.8" "Lineage enriched" "Detected in all" 40 "B-cells: 1462.8" "Cancer enriched" "Detected in many" 4 "lymphoma: 867.0" "Breast - Plasma cells, Lung - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000019, HPA056444" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 144 "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" CD79B "B29, Ig-beta, IGB, Igbeta" ENSG00000007312 "CD79b molecule" P40259 17 63928738-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 258.7" "Cell type enriched" "Detected in many" 4 "B-cells: 490.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "memory B-cell: 1119.4;naive B-cell: 1488.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1488.8" "Cancer enriched" "Detected in some" 6 "lymphoma: 657.0" "Prostate - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 2 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" CD80 "B7-1, B7.1, CD28LG, CD28LG1" ENSG00000121594 "CD80 molecule" P33681 3 119524293-119559614 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 2.9;lymphoid tissue: 6.6" "Group enriched" "Detected in some" 4 "B-cells: 9.1;Langerhans cells: 21.3;Macrophages: 7.2;monocytes: 19.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;T-reg: 1.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "lymphoma: 19.6" "Liver - Kupffer cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB025368, HPA050092" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 3 "CAB025368: , HPA050092: AB_2681012" "unprognostic (2.36e-1)" "unprognostic (1.55e-2)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.14e-3)" "unprognostic (1.02e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (9.03e-8)" "unprognostic (3.20e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (1.94e-2)" CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397802 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2015.8;Endometrial stromal cells: 1072.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 149.3;naive B-cell: 137.6" "Lineage enriched" "Detected in all" 4 "B-cells: 149.3" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 3: Basal prostatic cells - Lipid metabolism" 22 "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 203.0;Proximal enterocytes: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 537.1" "Group enriched" "Detected in all" 6 "B-cells: 308.8;granulocytes: 537.1;T-cells: 172.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Uncertain Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 30: Granulocytes - Unknown function" 5 Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" CD83 "BL11, HB15" ENSG00000112149 "CD83 molecule" Q01151 6 14117256-14136918 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 207.2" "Cell type enhanced" "Detected in many" "B-cells: 665.5;granulocytes: 358.9;Langerhans cells: 1778.3;Macrophages: 631.3;monocytes: 995.6;Schwann cells: 428.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "lymphoma: 133.1" "Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002509, HPA041454, HPA064421" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Nucleoplasm, Plasma membrane" "Nucleoli, Golgi apparatus" "CAB002509: AB_563641, HPA041454: AB_2677489, HPA064421: " "unprognostic (2.22e-3)" "unprognostic (1.92e-2)" "unprognostic (1.22e-1)" "unprognostic (6.39e-2)" "unprognostic (5.83e-2)" "unprognostic (3.02e-2)" "unprognostic (1.00e-2)" "unprognostic (9.05e-3)" "unprognostic (9.05e-2)" "unprognostic (3.91e-2)" "unprognostic (7.37e-2)" "unprognostic (6.68e-2)" "prognostic favorable (3.49e-4)" "unprognostic (2.30e-1)" "unprognostic (7.07e-2)" "unprognostic (1.40e-2)" "unprognostic (2.46e-2)" CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.6" "Cell type enhanced" "Detected in many" "granulocytes: 174.5;Hofbauer cells: 90.3;Kupffer cells: 136.0;Langerhans cells: 47.6;Macrophages: 109.6;T-cells: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 61 "Leukemia: 11.4;lymphoma: 8.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 151.9;Kupffer cells: 91.5;Langerhans cells: 191.7;Macrophages: 142.5;Microglial cells: 75.1;monocytes: 464.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 80.1;intermediate monocyte: 79.2;memory B-cell: 41.1;myeloid DC: 79.0;naive B-cell: 28.7;non-classical monocyte: 85.6" "Group enriched" "Detected in many" 18 "B-cells: 41.1;dendritic cells: 79.0;monocytes: 85.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 226.2" "Cell type enriched" "Detected in many" 4 "T-cells: 243.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 227.9;memory CD8 T-cell: 509.4;naive CD8 T-cell: 461.5" "Lineage enriched" "Detected in many" 19 "T-cells: 509.4" "Group enriched" "Detected in some" 9 "Leukemia: 4.0;lymphoma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA 490000 "Cluster 11: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 447.5" "Cell type enriched" "Detected in many" 11 "T-cells: 159.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 602.5;naive CD8 T-cell: 1058.1" "Lineage enriched" "Detected in all" 25 "T-cells: 1058.1" "Group enriched" "Detected in some" 9 "Leukemia: 8.7;Myeloma: 33.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2694.8;Ionocytes: 2140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 26 "basophil: 1961.8;eosinophil: 1159.2" "Lineage enriched" "Detected in all" 32 "granulocytes: 1961.8" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1200000 "Cluster 41: Basophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 133.0" "Cell type enhanced" "Detected in many" "Adipocytes: 312.1;Endothelial cells: 272.5;Kupffer cells: 141.1;Macrophages: 121.0;monocytes: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Cancer enhanced" "Detected in some" "Leukemia: 17.2;lymphoma: 6.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.2" "Group enriched" "Detected in many" 12 "NK-cells: 119.6;T-cells: 206.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.3;memory CD4 T-cell: 67.1;memory CD8 T-cell: 85.2;naive CD4 T-cell: 68.8;naive CD8 T-cell: 81.9;NK-cell: 79.7;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.7;T-cells: 117.3" "Cancer enhanced" "Detected in many" "Leukemia: 31.3;skin cancer: 14.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066754 Enhanced NA NA 85000 "Cluster 24: Non-specific - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" CD99 MIC2 ENSG00000002586 "CD99 molecule (Xg blood group)" P14209 X 2691187-2741309 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "CAB000020, HPA035304" Supported Approved "Golgi apparatus" NA NA 62000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" "CAB000020: AB_2076419, HPA035304: AB_10672861" "unprognostic (3.71e-3)" "unprognostic (2.90e-1)" "unprognostic (5.97e-3)" "unprognostic (7.01e-3)" "unprognostic (2.14e-2)" "unprognostic (6.98e-3)" "unprognostic (3.89e-3)" "unprognostic (1.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.87e-7)" "unprognostic (2.11e-2)" "unprognostic (2.18e-1)" "unprognostic (5.37e-2)" "unprognostic (3.61e-2)" CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.4;Inhibitory neurons: 54.8;Oligodendrocytes: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Oligodendrocytes - Unknown function" 7 "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 40: Prostatic glandular cells - Transcription" 1 Cytosol "Plasma membrane" "HPA039404: AB_10673530, HPA040787: AB_2677137" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.17e-2)" "unprognostic (9.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (9.20e-3)" "unprognostic (2.04e-1)" CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 82.1;Excitatory neurons: 80.6;Inhibitory neurons: 105.6;Oligodendrocyte precursor cells: 147.2;Oligodendrocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.9" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" HPA064747 Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 51: Oligodendrocytes - Unknown function" 7 Nucleoplasm "HPA064747: AB_2732719" "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favorable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (7.40e-2)" CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 111.9;Basal respiratory cells: 87.9;Suprabasal keratinocytes: 73.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 26.9" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" CDCP2 ENSG00000157211 "CUB domain containing protein 2" Q5VXM1 1 54132687-54153770 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031143 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 11: Neuronal - Sensory perception" "HPA031143: AB_10611819" "unprognostic (1.08e-1)" "unprognostic (5.16e-2)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-2)" "unprognostic (4.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.86e-2)" "unprognostic (2.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.67e-2)" "unprognostic (7.67e-6)" "unprognostic (2.37e-1)" "unprognostic (1.48e-1)" "unprognostic (5.12e-1)" "unprognostic (2.21e-2)" CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 191.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 256.1;Distal enterocytes: 307.5;Glandular and luminal cells: 313.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 43.1" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 35 "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" CDH10 ENSG00000040731 "Cadherin 10" Q9Y6N8 5 24487100-24644978 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 19.1" "Group enriched" "Detected in some" 20 "Astrocytes: 160.7;Excitatory neurons: 409.3;Inhibitory neurons: 206.7;Oligodendrocyte precursor cells: 458.5" "Cancer enriched" "Detected in some" 4 "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.1;testis cancer: 10.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010651, HPA012085" Approved Approved "Nucleoplasm,Cell Junctions" NA NA 270000 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA010651: AB_1078370, HPA012085: " "unprognostic (4.31e-3)" "unprognostic (2.77e-1)" "unprognostic (1.88e-1)" "unprognostic (3.66e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-3)" "unprognostic (6.27e-2)" "unprognostic (1.59e-7)" "unprognostic (1.65e-2)" "unprognostic (1.41e-1)" "unprognostic (8.74e-3)" CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 184.0;placenta: 118.1" "Cell type enhanced" "Detected in many" "Astrocytes: 88.2;Endometrial stromal cells: 113.5;Excitatory neurons: 117.7;Microglial cells: 138.7;Oligodendrocyte precursor cells: 148.6;Oligodendrocytes: 99.0;Ovarian stromal cells: 115.5;Peritubular cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 102.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_1, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" CDH12 "Br-cadherin, CDHB" ENSG00000154162 "Cadherin 12" P55289 5 21750673-22853344 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 11.3" "Group enriched" "Detected in some" 15 "Excitatory neurons: 829.6;Inhibitory neurons: 848.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.2;thyroid cancer: 2.6" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029325 Uncertain Uncertain Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA029325: AB_2672998" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (4.95e-2)" "unprognostic (8.61e-2)" "unprognostic (3.31e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.26e-2)" "unprognostic (1.34e-1)" "unprognostic (3.51e-2)" "unprognostic (3.25e-4)" "unprognostic (7.35e-2)" "unprognostic (3.48e-2)" "unprognostic (5.19e-2)" CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 80.0;skeletal muscle: 55.0" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 66.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 14 "cerebellum: 51.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Sarcoma: 32.4" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 19 "cerebellum: 24.8" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 79: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" CDH16 ENSG00000166589 "Cadherin 16" O75309 16 66908122-66918917 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 243.1" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 472.6" "Cancer enriched" "Detected in many" 15 "renal cancer: 96.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 15.9;Kidney cancer: 17.5;Uterine cancer: 9.2" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB013526, HPA036260" Enhanced NA NA 130000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "CAB013526: , HPA036260: AB_2675027" "unprognostic (1.07e-1)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (9.81e-2)" "unprognostic (4.24e-3)" "unprognostic (5.81e-2)" "unprognostic (5.58e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-2)" "prognostic favorable (1.02e-7)" "unprognostic (2.19e-1)" "unprognostic (1.99e-1)" "unprognostic (7.36e-3)" "unprognostic (2.34e-2)" CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 305.2" "Group enriched" "Detected in some" 11 "Distal enterocytes: 491.3;Enteroendocrine cells: 168.9;Intestinal goblet cells: 186.3;Paneth cells: 284.0;Proximal enterocytes: 312.2;Undifferentiated cells: 136.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 14.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 14.8" "Group enriched" "Detected in many" 5 "Bile duct cancer: 61.7;colorectal cancer: 158.4;Gastric cancer: 75.7;pancreatic cancer: 48.9" "Colon - Colon enterocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" CDH18 "CDH14, EY-CADHERIN" ENSG00000145526 "Cadherin 18" Q13634 5 19471296-20575873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.5;brain: 15.4;pituitary gland: 3.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 893.6;Inhibitory neurons: 667.7;Oligodendrocyte precursor cells: 233.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014416 Uncertain "Intracellular and membrane" "Cell adhesion" NA Yes "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" "HPA014416: AB_2668996" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (5.26e-7)" "unprognostic (6.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (8.78e-2)" "unprognostic (3.30e-2)" "unprognostic (1.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-2)" CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 35.8;intestine: 18.8" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 179.3;Schwann cells: 672.0" "Cancer enriched" "Detected in some" 21 "melanoma: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Sarcoma: 4.8;skin cancer: 12.4" "Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 320000 "Cluster 30: Heart muscle - Heart development" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA056332: AB_2683102" "unprognostic (1.63e-2)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (3.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.39e-2)" "unprognostic (9.33e-2)" "unprognostic (2.25e-2)" "unprognostic (4.58e-3)" "unprognostic (8.16e-3)" "unprognostic (8.21e-2)" "unprognostic (1.56e-5)" CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 189.1" "Cell type enhanced" "Detected in many" "Astrocytes: 206.5;Cardiomyocytes: 382.4;Cone photoreceptor cells: 132.5;Excitatory neurons: 300.3;Inhibitory neurons: 189.4;Oligodendrocyte precursor cells: 251.4" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686, CAB080169" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 30: Heart muscle - Heart development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane" "Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, CAB080169: , HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" CDH22 "C20orf25, dJ998H6.1" ENSG00000149654 "Cadherin 22" Q9UJ99 20 46173739-46308498 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 40.7" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 46.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012164, HPA012715" Uncertain Supported NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA012164: AB_1845902, HPA012715: " "unprognostic (2.41e-4)" "unprognostic (1.72e-2)" "unprognostic (3.10e-1)" "unprognostic (4.32e-3)" "unprognostic (3.39e-2)" "unprognostic (4.73e-1)" "unprognostic (4.32e-1)" "unprognostic (2.54e-2)" "unprognostic (5.54e-2)" "unprognostic (4.50e-4)" "unprognostic (2.62e-1)" "unprognostic (3.09e-1)" "unprognostic (7.26e-3)" "unprognostic (5.93e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (9.83e-2)" CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.2" "Cell type enhanced" "Detected in many" "Early spermatids: 52.7;Late spermatids: 82.5;Microglial cells: 32.2;monocytes: 75.0;Muller glia cells: 81.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 26.8;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 4 "monocytes: 38.2" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 950000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 10: Muller glia cells - Visual perception" "HPA017232: AB_1845903" "unprognostic (6.76e-2)" "unprognostic (2.86e-3)" "unprognostic (3.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (6.44e-3)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (9.23e-3)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "prognostic favorable (3.40e-4)" CDH24 CDH11L ENSG00000139880 "Cadherin 24" Q86UP0 14 23047062-23057538 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 10.7;Astrocytes: 8.7;Endothelial cells: 10.1;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074551 Approved Vesicles,Cytosol NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Cytosol Vesicles "HPA074551: " "unprognostic (2.30e-1)" "unprognostic (3.06e-2)" "unprognostic (4.15e-3)" "unprognostic (6.21e-2)" "unprognostic (1.27e-1)" "unprognostic (9.18e-2)" "unprognostic (6.68e-3)" "unprognostic (2.71e-2)" "unprognostic (5.97e-3)" "unprognostic (3.55e-1)" "unprognostic (4.18e-2)" "unprognostic (5.97e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-2)" "unprognostic (8.85e-2)" CDH26 VR20 ENSG00000124215 "Cadherin 26" Q8IXH8 20 59958423-60034011 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 7.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 11.9;Astrocytes: 17.0;Ciliated cells: 17.6;Club cells: 17.5;Ionocytes: 16.6;Oligodendrocytes: 13.9;Prostatic glandular cells: 30.6;Syncytiotrophoblasts: 14.3" "Group enriched" "Detected in some" 6 "cervical cancer: 1.5;head and neck cancer: 0.9;lung cancer: 2.3;prostate cancer: 3.6;urothelial cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.9" "Low region specificity" "Detected in some" "HPA015722, HPA047578" Uncertain Supported "Plasma membrane,Microtubules" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Microtubules "HPA015722: AB_2077659, HPA047578: AB_2680091" "unprognostic (2.42e-1)" "prognostic favorable (7.62e-4)" "unprognostic (4.71e-4)" "unprognostic (8.17e-2)" "unprognostic (9.40e-2)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "prognostic favorable (3.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (3.26e-4)" "unprognostic (8.24e-3)" "unprognostic (9.96e-7)" "unprognostic (1.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.3;ovary: 31.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 58.9;Basal respiratory cells: 153.8;Basal squamous epithelial cells: 68.3;Granulosa cells: 93.6;Melanocytes: 91.0;Oocytes: 57.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 12 "choroid plexus: 100.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 157.4" "Adipose visceral - Mesothelial cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 510000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" CDH4 R-CAD ENSG00000179242 "Cadherin 4" P55283 20 61252261-61940617 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 13.2;lymphoid tissue: 3.6;ovary: 6.1;skeletal muscle: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 148.9;Excitatory neurons: 52.7;Inhibitory neurons: 66.9;Oligodendrocyte precursor cells: 101.4;Oocytes: 32.3" "Group enriched" "Detected in many" 6 "glioma: 6.9;renal cancer: 3.4;thyroid cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015613 Supported "Plasma membrane" NA NA 19000 "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "HPA015613: AB_2732414" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "unprognostic (3.39e-4)" "unprognostic (2.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (6.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (6.78e-2)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 228.1" "Cell type enhanced" "Detected in many" "Adipocytes: 292.8;Endothelial cells: 190.1;Late spermatids: 84.9;Lymphatic endothelial cells: 152.3;Syncytiotrophoblasts: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.0;pancreatic cancer: 9.6;Rhabdoid: 12.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 6 "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 45.8;Excitatory neurons: 64.6;Microglial cells: 37.6;Oligodendrocyte precursor cells: 57.1;Proximal tubular cells: 183.4;Smooth muscle cells: 55.3" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.6;ovarian cancer: 81.5;Uterine cancer: 44.9" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" CDH7 ENSG00000081138 "Cadherin 7" Q9ULB5 18 65750252-65890337 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 4.3;retina: 3.5" "Group enriched" "Detected in some" 5 "Excitatory neurons: 44.0;Horizontal cells: 57.3;Inhibitory neurons: 107.2;Muller glia cells: 34.0" "Cancer enhanced" "Detected in single" "prostate cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.3;Sarcoma: 3.3" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061419 Supported NA NA "Cluster 28: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" "HPA061419: AB_2684511" "unprognostic (2.81e-3)" "unprognostic (6.95e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (3.45e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-3)" "unprognostic (2.88e-1)" "unprognostic (4.28e-4)" "unprognostic (2.70e-2)" "unprognostic (1.49e-1)" "unprognostic (1.72e-1)" CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.5;seminal vesicle: 4.8" "Group enriched" "Detected in some" 16 "Excitatory neurons: 213.3;Inhibitory neurons: 225.3;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 9.8;Rhabdoid: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 870000 "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "HPA014908: AB_1845908, HPA076441: " "unprognostic (1.91e-1)" "unprognostic (2.41e-1)" "unprognostic (4.02e-2)" "unprognostic (7.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.71e-2)" "unprognostic (3.66e-2)" "unprognostic (5.41e-2)" "unprognostic (2.85e-1)" "unprognostic (6.59e-2)" "unprognostic (2.91e-4)" "unprognostic (6.02e-2)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" CDH9 ENSG00000113100 "Cadherin 9" Q9ULB4 5 26880597-27121150 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;kidney: 5.6" "Group enriched" "Detected in some" 33 "Excitatory neurons: 296.6;Inhibitory neurons: 439.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.0" "Group enriched" "Detected in many" 5 "B-cells: 2.6;granulocytes: 5.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007167 Approved Approved "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "HPA007167: AB_1078489" "unprognostic (1.49e-1)" "unprognostic (2.27e-4)" CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 304.3;skin 1: 208.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 360.2;Rod photoreceptor cells: 214.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.9" "Adipose visceral - T-cells, Colon - Colon enterocytes, Liver - NK-cells (Liver), Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid - T-cells" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.1" "Low region specificity" "Detected in all" "HPA010795, HPA036819" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 55000 "Cluster 15: NK-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Golgi apparatus" "HPA010795: , HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 262.0" "Group enriched" "Detected in some" 4 "Late spermatids: 695.5;Proximal enterocytes: 492.7" "Group enriched" "Detected in many" 14 "colorectal cancer: 9.1;liver cancer: 5.7;pancreatic cancer: 11.7;renal cancer: 8.6;stomach cancer: 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 4.1;Gastric cancer: 5.9;liver cancer: 3.9;pancreatic cancer: 9.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "hypothalamus: 2.2" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 8800000 "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA012569: AB_1845298, HPA017053: AB_1845297" "unprognostic (1.34e-2)" "unprognostic (8.90e-4)" "unprognostic (3.82e-2)" "unprognostic (8.51e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (6.66e-2)" "unprognostic (2.06e-3)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (7.66e-3)" "unprognostic (1.75e-1)" "prognostic favorable (9.29e-4)" "unprognostic (6.58e-2)" "unprognostic (3.55e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 35.2;fallopian tube: 105.2" "Cell type enhanced" "Detected in many" "Astrocytes: 161.9;Ciliated cells: 249.2;Enteroendocrine cells: 90.7;Excitatory neurons: 67.8;Inhibitory neurons: 61.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 100.8" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lymphoma: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 16.1" HPA011218 Supported NA NA "Cluster 34: B-cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Ciliated cells - Cilium assembly" 6 "HPA011218: AB_1078886" "unprognostic (4.38e-4)" "unprognostic (9.18e-2)" "unprognostic (8.16e-3)" "unprognostic (8.08e-3)" "unprognostic (5.23e-2)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.70e-3)" "unprognostic (3.51e-3)" CDHR4 "CDH29, VLLR9392" ENSG00000187492 "Cadherin related family member 4" A6H8M9 3 49790732-49799873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 57.4" "Cell type enriched" "Detected in some" 16 "Ciliated cells: 107.6" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA076277 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 59: Fallopian tube - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" "HPA076277: AB_2732306" "unprognostic (1.50e-4)" "unprognostic (4.87e-2)" "unprognostic (6.00e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (2.45e-3)" "unprognostic (6.35e-7)" "unprognostic (1.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.12e-1)" "unprognostic (9.61e-2)" "unprognostic (2.35e-1)" "unprognostic (9.07e-11)" "unprognostic (2.65e-1)" "unprognostic (3.70e-2)" "unprognostic (1.13e-2)" "unprognostic (2.37e-1)" CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 288.9;liver: 126.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 655.8;Intestinal goblet cells: 201.7;Paneth cells: 440.9;Proximal enterocytes: 2282.1" "Cancer enhanced" "Detected in many" "liver cancer: 61.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced "Intracellular and membrane" Other NA NA 190000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "CAB025004: , HPA009081: AB_1079428, HPA009173: AB_1079429" "unprognostic (7.65e-2)" "unprognostic (1.42e-1)" "unprognostic (9.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-3)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.75e-2)" "unprognostic (6.36e-2)" "unprognostic (7.95e-2)" "unprognostic (5.07e-2)" "unprognostic (5.01e-2)" "unprognostic (3.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" CDIP1 "C16orf5, CDIP, LITAFL" ENSG00000089486 "Cell death inducing p53 target 1" Q9H305 16 4510669-4538828 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 168.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049352 Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" 10 Centrosome Nucleoplasm "HPA049352: AB_2680724" "unprognostic (6.38e-3)" "unprognostic (3.70e-3)" "unprognostic (2.95e-2)" "unprognostic (2.50e-3)" "unprognostic (2.74e-2)" "unprognostic (2.56e-2)" "unprognostic (3.48e-1)" "unprognostic (8.26e-2)" "unprognostic (3.68e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.14e-5)" "unprognostic (9.05e-2)" "prognostic favorable (1.14e-6)" "unprognostic (1.43e-2)" "unprognostic (3.51e-2)" "unprognostic (9.88e-2)" "unprognostic (4.65e-2)" CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863414 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 4: Extravillous trophoblasts - Unknown function" 47 "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: AB_2683182" "unprognostic (7.81e-2)" "prognostic favorable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" CDON "CDO, CDON1, Ihog, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.3;Inhibitory neurons: 47.6;Mesothelial cells: 49.9;Muller glia cells: 33.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 14.9" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Neurons - Neuronal signaling" 2 "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 5 "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Smooth muscle cells - Signal transduction" 29 "Endoplasmic reticulum" "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 238.1" "Group enriched" "Detected in many" 5 "Distal enterocytes: 797.7;Paneth cells: 241.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "eosinophil: 44.1;neutrophil: 26.9" "Lineage enriched" "Detected in many" 13 "granulocytes: 44.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" "No annotated function" NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 5: Enterocytes - Absorption" 2 "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.7;Suprabasal keratinocytes: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" CEACAM21 "FLJ13540, R29124_1" ENSG00000007129 "CEA cell adhesion molecule 21" Q3KPI0 19 41549518-41586844 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.3;lymphoid tissue: 10.0" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;Hofbauer cells: 9.5;Kupffer cells: 10.6;Late spermatids: 10.8;Microglial cells: 14.3;Plasma cells: 11.0;T-cells: 7.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Leukemia: 3.0;lymphoma: 1.5;Myeloma: 5.8" "Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" HPA043411 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 35: RS4;11 - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA043411: AB_10794886" "unprognostic (2.55e-1)" "unprognostic (1.61e-3)" "unprognostic (5.73e-2)" "prognostic favorable (1.89e-5)" "unprognostic (2.57e-1)" "unprognostic (8.02e-4)" "unprognostic (3.04e-1)" "unprognostic (2.05e-3)" "unprognostic (1.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (3.37e-6)" "unprognostic (2.09e-1)" "unprognostic (3.67e-1)" "unprognostic (1.12e-3)" "unprognostic (1.37e-1)" CEACAM3 "CD66d, CGM1" ENSG00000170956 "CEA cell adhesion molecule 3" P40198 19 41796587-41811554 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.8" "Cell type enriched" "Detected in some" 7 "Paneth cells: 47.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Immune cell enriched" "Detected in many" 6 "neutrophil: 290.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 290.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - NK-cells (Lung), Stomach - Neutrophils, Thyroid - Neutrophils" HPA011041 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Neutrophils - Degranulation" 4 "HPA011041: AB_1078481" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (8.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.68e-2)" "unprognostic (8.44e-2)" "unprognostic (2.83e-1)" CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 179.4;esophagus: 189.8;intestine: 213.5;lung: 277.7;salivary gland: 172.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1478.7;Alveolar cells type 2: 210.1;Club cells: 252.8;Distal enterocytes: 438.9;Paneth cells: 364.4" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "pancreatic cancer: 386.8" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 77: Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 25 "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 631.6" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1565.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.3;colorectal cancer: 3.4;ovarian cancer: 3.2" "Colon - Colon enterocytes" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" CEBPZOS CEBPZ-AS1 ENSG00000218739 "CEBPZ opposite strand" A8MTT3 2 37196488-37216193 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053866 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA053866: AB_2682283" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" "unprognostic (8.05e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (2.34e-2)" "unprognostic (2.40e-2)" "unprognostic (5.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (3.46e-7)" "unprognostic (3.69e-2)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.1;Basal respiratory cells: 28.6;Ciliated cells: 56.5;Club cells: 31.1;Glandular and luminal cells: 35.4;Ionocytes: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 280000 "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;skin 1: 24.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 50.4;Oligodendrocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636463-48662886 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.7;pituitary gland: 7.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.1;Cone photoreceptor cells: 22.1;Excitatory neurons: 9.8;Horizontal cells: 20.8;Inhibitory neurons: 10.3;Rod photoreceptor cells: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA062866: AB_2684886" "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (4.89e-1)" "unprognostic (9.12e-4)" "unprognostic (1.51e-1)" "unprognostic (1.59e-6)" "unprognostic (3.61e-6)" "unprognostic (1.86e-1)" "unprognostic (1.46e-3)" "unprognostic (5.07e-2)" "unprognostic (2.13e-3)" "unprognostic (2.87e-3)" "unprognostic (3.26e-3)" "unprognostic (9.53e-2)" "unprognostic (1.42e-1)" "unprognostic (3.86e-2)" "unprognostic (1.73e-1)" CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 89.5;placenta: 77.0" "Cell type enhanced" "Detected in many" "NK-cells: 487.8;T-cells: 189.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 150000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 58: Placenta - Pregnancy" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 276.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 82.0;Excitatory neurons: 41.5;Horizontal cells: 95.0;Inhibitory neurons: 43.7" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.3;Rhabdoid: 27.0" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 3 Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" CEP170 "FAM68A, KAB, KIAA0470" ENSG00000143702 "Centrosomal protein 170" Q5SW79 1 243124428-243255348 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 52.0;brain: 24.6;testis: 87.3" "Cell type enriched" "Detected in many" 8 "Late spermatids: 2467.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042151, HPA045597, HPA045787" Uncertain Enhanced Centrosome,Cytosol NA No 21000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Testis - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Late spermatids - Unknown function" 12 Centrosome Cytosol "HPA042151: AB_2677876, HPA045597: AB_2732522, HPA045787: AB_2679453" "unprognostic (2.97e-1)" "unprognostic (2.49e-3)" "unprognostic (8.84e-2)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (7.60e-2)" "unprognostic (6.83e-5)" "unprognostic (8.05e-2)" "unprognostic (9.88e-3)" "unprognostic (7.09e-2)" "unprognostic (3.52e-2)" "unprognostic (6.65e-2)" "prognostic unfavorable (1.30e-9)" "unprognostic (2.21e-2)" "unprognostic (2.17e-1)" "unprognostic (6.49e-3)" "unprognostic (9.62e-3)" CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999174-167052718 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell type enhanced" "Detected in all" "Early spermatids: 232.1;Late spermatids: 281.8;Spermatocytes: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Supported Supported Centrosome NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 4 Centrosome "HPA071876: AB_2686467" "unprognostic (9.14e-2)" "unprognostic (2.24e-1)" "unprognostic (3.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (9.59e-2)" "unprognostic (1.00e-1)" "unprognostic (6.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" CEP95 "CCDC45, DKFZp667E1824" ENSG00000258890 "Centrosomal protein 95" Q96GE4 17 64506865-64542461 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052426, HPA052428, HPA061371" Approved Uncertain "Centriolar satellite,Cytosol" NA No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 13 Cytosol "Centriolar satellite" "HPA052426: AB_2681827, HPA052428: AB_2681829, HPA061371: AB_2684495" "unprognostic (1.28e-2)" "unprognostic (9.12e-2)" "unprognostic (3.66e-3)" "unprognostic (4.09e-2)" "unprognostic (3.30e-2)" "prognostic favorable (5.78e-4)" "prognostic unfavorable (2.52e-5)" "unprognostic (6.57e-3)" "unprognostic (7.88e-3)" "unprognostic (1.54e-1)" "unprognostic (1.64e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (5.76e-5)" "unprognostic (3.48e-1)" "unprognostic (1.84e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-3)" CERS1 "LAG1, LASS1, UOG1" ENSG00000223802 "Ceramide synthase 1" P27544 19 18868545-18896727 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 166.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 119.0" "Group enriched" "Detected in many" 5 "glioma: 13.5;melanoma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA045724 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Endoplasmic reticulum" "HPA045724: AB_10969762" "unprognostic (8.25e-2)" "unprognostic (8.91e-2)" "unprognostic (2.12e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.47e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (4.02e-1)" "unprognostic (7.04e-3)" "unprognostic (3.52e-3)" "unprognostic (1.92e-1)" "unprognostic (4.59e-2)" "unprognostic (2.99e-2)" "unprognostic (3.15e-2)" "unprognostic (9.15e-2)" "unprognostic (3.49e-1)" CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" 8 "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 53.6;skin 1: 62.0;vagina: 29.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 31.8;Basal squamous epithelial cells: 38.6;Early spermatids: 23.9;Late spermatids: 18.3;Spermatocytes: 24.1;Squamous epithelial cells: 49.4;Suprabasal keratinocytes: 86.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Esophageal cancer: 2.9;head and neck cancer: 10.6" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 4 Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 122.6;Suprabasal keratinocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 40 "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129289-50167533 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006780, HPA026589" Approved Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA006780: , HPA026589: AB_1852727" "unprognostic (1.59e-2)" "unprognostic (9.83e-2)" "unprognostic (5.17e-2)" "unprognostic (3.64e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-3)" "prognostic unfavorable (4.63e-5)" "unprognostic (5.56e-2)" "unprognostic (1.65e-2)" "unprognostic (9.26e-2)" "unprognostic (1.88e-3)" "unprognostic (5.67e-2)" "prognostic unfavorable (9.33e-11)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "prognostic favorable (5.76e-5)" "unprognostic (3.26e-1)" CERS6 LASS6 ENSG00000172292 "Ceramide synthase 6" Q6ZMG9 2 168456249-168775134 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Inflammatory response, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 148.5;Excitatory neurons: 262.5;Inhibitory neurons: 280.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 5.4" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044683 Approved NA No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 2 "HPA044683: AB_10965059" "unprognostic (2.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.92e-3)" "prognostic unfavorable (7.31e-4)" "unprognostic (3.24e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (9.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.93e-2)" "unprognostic (2.38e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-2)" "unprognostic (2.41e-1)" "unprognostic (4.80e-2)" CFAP46 "bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40" ENSG00000171811 "Cilia and flagella associated protein 46" Q8IYW2 10 132808392-132942823 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 15.7;skeletal muscle: 29.1;testis: 40.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 89.2;Cone photoreceptor cells: 56.1;Excitatory neurons: 41.3;Rod photoreceptor cells: 87.3;Spermatocytes: 48.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037786, HPA038034, HPA038867, HPA038868" Uncertain NA NA "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Ciliated cells - Cilium assembly" "HPA037786: AB_10672392, HPA038034: AB_2675796, HPA038867: AB_2676246, HPA038868: AB_2676247" "unprognostic (2.83e-2)" "unprognostic (4.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.19e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-1)" "unprognostic (4.11e-1)" "unprognostic (5.40e-2)" "unprognostic (6.41e-3)" "unprognostic (1.39e-1)" "unprognostic (1.64e-4)" "unprognostic (1.21e-2)" "unprognostic (8.08e-2)" "unprognostic (4.56e-3)" "unprognostic (2.08e-2)" CFAP47 "CHDC2, CXorf22, CXorf30, CXorf59, FLJ36601, MGC34831, RP13-11B7.1" ENSG00000165164 "Cilia and flagella associated protein 47" Q6ZTR5 X 35919734-36385317 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.6;pituitary gland: 1.7;retina: 1.4" "Cell type enhanced" "Detected in some" "Astrocytes: 43.0;Ciliated cells: 55.3;Cone photoreceptor cells: 13.6;Rod photoreceptor cells: 11.9" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "HPA044633, HPA054859" Uncertain NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" "HPA044633: AB_10960684, HPA054859: AB_2682627" "unprognostic (1.88e-1)" "unprognostic (4.38e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (1.09e-1)" "unprognostic (3.13e-2)" "unprognostic (2.15e-1)" "unprognostic (4.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (5.61e-2)" "unprognostic (1.50e-5)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "unprognostic (1.48e-2)" "unprognostic (5.19e-3)" CFAP54 "C12orf55, C12orf63, FLJ31514, FLJ44112" ENSG00000188596 "Cilia and flagella associated protein 54" Q96N23 12 96489571-96875555 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 6.7;retina: 5.8" "Cell type enhanced" "Detected in many" "Astrocytes: 25.7;Ciliated cells: 71.3;Early spermatids: 37.9;Excitatory neurons: 21.2;Oligodendrocytes: 44.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039897 Enhanced Approved Microtubules,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" Microtubules Cytosol "HPA039897: AB_10674427" "unprognostic (1.87e-4)" "unprognostic (3.63e-2)" "unprognostic (8.07e-2)" "unprognostic (7.89e-2)" "unprognostic (4.66e-2)" "unprognostic (5.55e-2)" "unprognostic (2.75e-2)" "unprognostic (2.91e-2)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "unprognostic (2.86e-1)" "unprognostic (2.36e-1)" "unprognostic (3.55e-5)" "unprognostic (2.72e-2)" "unprognostic (3.35e-1)" "unprognostic (3.26e-2)" "unprognostic (8.00e-2)" CFAP57 "FLJ32000, WDR65" ENSG00000243710 "Cilia and flagella associated protein 57" Q96MR6 1 43172330-43254358 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.6;fallopian tube: 22.7;testis: 15.3" "Group enriched" "Detected in some" 6 "Ciliated cells: 71.9;Early spermatids: 49.7;Late spermatids: 22.4;Spermatocytes: 21.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.9" "Region enhanced" "Detected in all" "choroid plexus: 23.2" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.1;lymphoma: 3.7" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002736, HPA028623" Enhanced Approved Cytosol NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "HPA002736: AB_2272982, HPA028623: AB_10603234" "unprognostic (1.15e-2)" "unprognostic (2.29e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.02e-4)" "unprognostic (2.50e-2)" "unprognostic (3.71e-1)" "unprognostic (2.42e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-1)" "unprognostic (2.05e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-2)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-2)" "unprognostic (7.78e-2)" CFAP61 "C20orf26, CaM-IP3, dJ1002M8.3, DKFZP434K156" ENSG00000089101 "Cilia and flagella associated protein 61" Q8NHU2 20 20052514-20360703 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 11.7;heart muscle: 12.0;skeletal muscle: 27.6;testis: 15.0" "Group enriched" "Detected in some" 4 "Early spermatids: 90.5;Late spermatids: 78.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8;skin cancer: 5.0" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009079 Approved NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" "HPA009079: AB_1078344" "unprognostic (5.93e-2)" "unprognostic (1.27e-1)" "unprognostic (6.73e-2)" "unprognostic (1.38e-3)" "unprognostic (6.20e-3)" "unprognostic (3.67e-3)" "unprognostic (8.58e-4)" "unprognostic (8.24e-2)" "unprognostic (8.29e-2)" "unprognostic (3.11e-1)" "unprognostic (1.86e-2)" "unprognostic (1.56e-1)" "unprognostic (2.76e-4)" "unprognostic (2.77e-1)" "unprognostic (9.27e-2)" "unprognostic (3.10e-3)" "unprognostic (3.06e-1)" CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.4;intestine: 43.6;pancreas: 192.0" "Group enriched" "Detected in many" 4 "Ductal cells: 590.0;Late spermatids: 149.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 24.2;Gastric cancer: 9.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 94 "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" CGRRF1 "CGR19, RNF197" ENSG00000100532 "Cell growth regulator with ring finger domain 1" Q99675 14 54509812-54539292 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 163.4;Spermatocytes: 102.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002930 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 57: Platelets - Hemostasis" 26 Nucleoplasm Vesicles "HPA002930: AB_1078507" "unprognostic (1.81e-1)" "unprognostic (3.76e-1)" "unprognostic (5.61e-2)" "unprognostic (4.38e-1)" "unprognostic (1.01e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.58e-2)" "unprognostic (2.63e-1)" "unprognostic (7.29e-2)" "unprognostic (2.64e-3)" "prognostic favorable (2.57e-8)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.48e-1)" "unprognostic (1.74e-1)" CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Mitotic cells (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 9: Endometrial stromal cells - Transcription" 18 Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563197-73687111 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 44.6;Excitatory neurons: 60.5;Inhibitory neurons: 57.1;Oligodendrocyte precursor cells: 62.7;Oligodendrocytes: 70.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Nuclear speckles, Vesicles" Cytosol "HPA026782: AB_1846654, HPA052062: AB_2681714" "unprognostic (9.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.10e-2)" "unprognostic (9.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.65e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-2)" "unprognostic (2.19e-1)" "unprognostic (3.51e-1)" "unprognostic (2.76e-2)" CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 195.0;Oocytes: 201.5;Suprabasal keratinocytes: 185.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 366.4" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 21: Testis - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" 53 "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.0;ovary: 32.7" "Cell type enhanced" "Detected in many" "Astrocytes: 212.1;Excitatory neurons: 409.9;Inhibitory neurons: 307.2;Oligodendrocyte precursor cells: 861.7;Schwann cells: 403.3" "Cancer enhanced" "Detected in many" "glioma: 15.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.8;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 38 "B-cells: 3.8" "Group enriched" "Detected in many" 7 "Rhabdoid: 38.6;skin cancer: 30.5" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" "Developmental protein" NA NA 5800000000 "Cluster 34: B-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "CAB026120: , HPA003345: AB_1078516" "unprognostic (5.54e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "unprognostic (7.14e-3)" "unprognostic (1.16e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (5.14e-1)" "unprognostic (1.06e-1)" "unprognostic (7.81e-2)" "unprognostic (3.51e-1)" "prognostic favorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (6.07e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" CHML REP-2 ENSG00000203668 "CHM like Rab escort protein" P26374 1 241628851-241640369 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 158.8;monocytes: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029627, HPA029628, HPA062967" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 40: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 28: Dendritic cells - Antigen presentation" "Nucleoplasm, Cytosol" "HPA029627: AB_2756314, HPA029628: AB_10603784, HPA062967: AB_2797269" "unprognostic (1.63e-1)" "unprognostic (6.84e-2)" "unprognostic (3.57e-1)" "unprognostic (8.00e-2)" "unprognostic (2.46e-1)" "unprognostic (5.66e-2)" "prognostic unfavorable (9.23e-5)" "unprognostic (1.90e-2)" "unprognostic (3.37e-2)" "unprognostic (8.01e-3)" "unprognostic (3.02e-3)" "unprognostic (3.68e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.03e-3)" "unprognostic (1.09e-1)" CHODL "C21orf68, FLJ12627, MT75, PRED12" ENSG00000154645 Chondrolectin Q9H9P2 21 17901263-18267373 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.7;testis: 30.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 37.7;Oligodendrocyte precursor cells: 11.8;Oligodendrocytes: 46.6;Oocytes: 15.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 1.5" "Lineage enriched" "Detected in single" 7 "T-cells: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.3;Rhabdoid: 4.8" "Colon - Enteric glia cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 4 "basal ganglia: 3.9;hypothalamus: 12.3;pons and medulla: 10.9" "Group enriched" "Detected in all" 4 "olfactory bulb: 99.3;spinal cord: 66.1" "HPA017282, HPA057559" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 1: Neuronal - Visual perception" "Cluster 9: Endometrial stromal cells - Transcription" 11 Cytosol Centrosome "HPA017282: AB_1846687, HPA057559: " "unprognostic (3.91e-1)" "unprognostic (3.18e-2)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.18e-6)" "unprognostic (6.74e-2)" "unprognostic (6.82e-2)" "unprognostic (1.06e-3)" "unprognostic (6.79e-2)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.87e-1)" "unprognostic (4.83e-2)" "unprognostic (1.02e-1)" CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 652.4;Mucus glandular cells: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.8;eosinophil: 14.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 1 Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 44.0;prostate: 28.7;salivary gland: 28.0" "Cell type enriched" "Detected in some" 5 "Prostatic glandular cells: 48.9" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 5 "amygdala: 42.4;basal ganglia: 59.5;cerebral cortex: 69.7;hippocampal formation: 63.2;white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 3.4;Neuroblastoma: 8.7;prostate cancer: 2.5" "Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 40: Prostatic glandular cells - Transcription" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 34.9;intestine: 20.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 71.7;Excitatory neurons: 47.5;Inhibitory neurons: 113.6" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.0" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 776.4;Inhibitory neurons: 594.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.4" "Heart muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46383789-46391776 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;intestine: 5.9;lymphoid tissue: 14.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 44.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.1" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" CHRM5 ENSG00000184984 "Cholinergic receptor muscarinic 5" P08912 15 33968497-34067458 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.7" "Cell type enriched" "Detected in some" 7 "Oligodendrocytes: 166.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "hypothalamus: 13.2" "Low region specificity" "Detected in many" HPA013172 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA013172: AB_1854212" "unprognostic (8.19e-2)" "unprognostic (2.13e-1)" "unprognostic (7.67e-2)" "unprognostic (4.32e-1)" "unprognostic (3.05e-3)" "unprognostic (2.77e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-2)" "unprognostic (4.61e-4)" "unprognostic (7.95e-2)" "unprognostic (1.33e-6)" "unprognostic (1.42e-1)" "unprognostic (4.53e-2)" "unprognostic (1.38e-1)" "unprognostic (9.07e-2)" CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 164.1" "Cell type enriched" "Detected in some" 11 "Skeletal myocytes: 150.3" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 15 "cerebral cortex: 27.1;hippocampal formation: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Sarcoma: 107.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "prostate: 28.1" "Group enriched" "Detected in some" 10 "Horizontal cells: 28.3;Inhibitory neurons: 14.1;Prostatic glandular cells: 21.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in all" "thalamus: 157.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 26.6" "Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 4.9" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 38.1;lymphoid tissue: 64.2;retina: 51.9" "Cell type enriched" "Detected in some" 6 "Cone photoreceptor cells: 407.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 170.3" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;liver: 56.6;parathyroid gland: 12.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 24.4;Hepatocytes: 29.4;Horizontal cells: 49.7" "Cancer enhanced" "Detected in some" "liver cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 36.5;pons: 34.3;thalamus: 57.0" CAB034064 Uncertain NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 5 "CAB034064: AB_2080535" "unprognostic (3.40e-1)" "unprognostic (1.71e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-1)" "unprognostic (8.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-1)" "unprognostic (2.10e-3)" "unprognostic (5.72e-4)" "unprognostic (9.02e-3)" "unprognostic (9.79e-4)" "unprognostic (6.77e-2)" "unprognostic (1.08e-1)" "unprognostic (3.81e-2)" CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Oocytes: 104.4;Spermatogonia: 27.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 44: Oocytes - Unknown function" 1 "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" CHRNA7 ENSG00000175344 "Cholinergic receptor nicotinic alpha 7 subunit" P36544 15 31923438-32173018 "FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.5;intestine: 9.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 31.2;Horizontal cells: 29.0;Inhibitory neurons: 29.4;Intestinal goblet cells: 31.1;Proximal enterocytes: 27.3;Spermatogonia: 16.2" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 16.8" "Colon - Colon enteroendocrine cells" "HPA029422, CAB033624" Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 4 "CAB033624: AB_784835, HPA029422: AB_10600863" "unprognostic (3.43e-2)" "unprognostic (8.44e-2)" "unprognostic (2.02e-1)" "unprognostic (4.61e-4)" "unprognostic (6.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.14e-2)" "unprognostic (5.08e-2)" "unprognostic (1.63e-1)" "unprognostic (4.31e-2)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-2)" "unprognostic (4.36e-3)" "unprognostic (5.44e-2)" "unprognostic (7.41e-3)" "unprognostic (2.43e-1)" CHRNB1 CHRNB ENSG00000170175 "Cholinergic receptor nicotinic beta 1 subunit" P11230 17 7445061-7457710 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 152.8;tongue: 55.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 38.6;Skeletal myocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005822, CAB011200" Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 8: Immune cells - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "CAB011200: AB_262151, HPA005822: AB_1079484" "unprognostic (2.89e-2)" "unprognostic (3.43e-1)" "unprognostic (1.08e-1)" "unprognostic (2.67e-2)" "unprognostic (4.19e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-2)" "unprognostic (3.56e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" "unprognostic (2.49e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" CHRNB3 ENSG00000147432 "Cholinergic receptor nicotinic beta 3 subunit" Q05901 8 42697366-42737407 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "brain: 2.7;pancreas: 1.8;retina: 3.7;testis: 1.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 2.1;Horizontal cells: 6.9;Inhibitory neurons: 2.8" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.6" "Group enriched" "Detected in many" 4 "cerebellum: 25.9;midbrain: 22.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Rhabdoid: 2.2" "Testis - Early spermatids" "Region enhanced" "Detected in many" "midbrain: 6.9" "Low region specificity" "Detected in all" HPA045555 Enhanced NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA045555: AB_10960891" "unprognostic (8.63e-2)" "unprognostic (4.12e-1)" "unprognostic (7.29e-2)" "unprognostic (1.62e-1)" CHRNB4 ENSG00000117971 "Cholinergic receptor nicotinic beta 4 subunit" P30926 15 78624111-78727754 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.4;lymphoid tissue: 2.9;retina: 2.7;testis: 5.6" "Group enriched" "Detected in some" 18 "Early spermatids: 37.6;Late spermatids: 55.8;Oocytes: 56.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Neuroblastoma: 34.5" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.3;pons and medulla: 1.4;thalamus: 4.2" HPA059484 Approved "Endoplasmic reticulum,Cell Junctions" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" "Endoplasmic reticulum" "Cell Junctions" "HPA059484: " "unprognostic (4.74e-2)" "unprognostic (4.54e-1)" "unprognostic (1.26e-2)" "unprognostic (8.77e-5)" "unprognostic (8.15e-2)" "unprognostic (6.43e-3)" "unprognostic (1.10e-1)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.19e-1)" "unprognostic (1.40e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-4)" "unprognostic (7.00e-3)" "unprognostic (2.58e-1)" "unprognostic (8.50e-2)" "unprognostic (7.76e-2)" CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 55.6" "Cell type enriched" "Detected in some" 10 "Skeletal myocytes: 33.2" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Sarcoma: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065404 Supported "Plasma membrane" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" "Plasma membrane" "HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.4;Horizontal cells: 14.5;Muller glia cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 680000 "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Cytosol "HPA012884: AB_1846710, HPA051545: AB_2681529" "unprognostic (5.40e-3)" "unprognostic (3.62e-2)" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (3.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (4.54e-2)" "prognostic favorable (4.05e-4)" "unprognostic (8.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-2)" "unprognostic (3.73e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-1)" CHST12 "C4S-2, C4ST2" ENSG00000136213 "Carbohydrate sulfotransferase 12" Q9NRB3 7 2403588-2448484 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cells: 269.6;Syncytiotrophoblasts: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041680 Approved Approved "Golgi apparatus" NA NA 960000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Golgi apparatus" "HPA041680: AB_10959789" "unprognostic (4.12e-2)" "unprognostic (3.56e-1)" "unprognostic (3.04e-3)" "unprognostic (1.59e-1)" "unprognostic (2.05e-3)" "unprognostic (7.15e-2)" "unprognostic (2.01e-3)" "unprognostic (1.34e-1)" "unprognostic (3.20e-2)" "unprognostic (4.88e-2)" "prognostic favorable (1.32e-5)" "unprognostic (9.61e-2)" "unprognostic (1.66e-3)" "unprognostic (4.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470984-40473158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.5;Extravillous trophoblasts: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved "Golgi apparatus" NA NA 20000 "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "HPA057697: AB_2683505, HPA071601: AB_2686425" "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" CHST15 "BRAG, GALNAC4S-6ST, KIAA0598" ENSG00000182022 "Carbohydrate sulfotransferase 15" Q7LFX5 10 124007668-124093598 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 61.1;Lymphatic endothelial cells: 55.2;monocytes: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 69.2" "Group enriched" "Detected in many" 11 "granulocytes: 69.2;monocytes: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017584 Approved Approved Centrosome,Cytosol NA NA 690000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol Centrosome "HPA017584: AB_1849437" "unprognostic (1.19e-1)" "unprognostic (2.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (4.12e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-2)" "unprognostic (2.40e-2)" "unprognostic (7.62e-3)" "unprognostic (7.90e-2)" "unprognostic (8.16e-2)" "prognostic unfavorable (2.22e-7)" "unprognostic (6.47e-3)" "unprognostic (7.80e-2)" "unprognostic (4.63e-3)" "unprognostic (5.26e-3)" CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.3" "Cell type enhanced" "Detected in many" "monocytes: 109.1;Muller glia cells: 92.5;NK-cells: 145.7;Plasma cells: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" CHST3 "C6ST, C6ST1" ENSG00000122863 "Carbohydrate sulfotransferase 3" Q7LGC8 10 71964395-72013558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 25.0;Oligodendrocytes: 25.2;Sertoli cells: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047523, HPA055704" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 690000 "Cluster 74: Spermatids - Flagellum assembly" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Golgi apparatus, Cytosol" "HPA047523: AB_2680075, HPA055704: AB_2682891" "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "unprognostic (1.13e-3)" "unprognostic (1.16e-3)" "unprognostic (2.44e-1)" "unprognostic (4.67e-2)" "unprognostic (4.79e-2)" "unprognostic (7.53e-2)" "unprognostic (7.99e-2)" "unprognostic (3.71e-2)" "unprognostic (2.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.40e-2)" "unprognostic (2.65e-2)" "unprognostic (7.77e-2)" "unprognostic (2.56e-2)" "unprognostic (2.54e-3)" CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528530-75536108 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 84.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.8;Enteroendocrine cells: 6.2;Excitatory neurons: 2.1;Intestinal goblet cells: 6.1;Paneth cells: 3.2;Proximal enterocytes: 9.8" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.4;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.4" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "HPA043804, HPA068029" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA043804: AB_10960563, HPA068029: " "unprognostic (6.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-2)" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (2.09e-2)" "unprognostic (9.03e-3)" "unprognostic (4.27e-2)" "unprognostic (2.05e-3)" "unprognostic (3.56e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 60.2;Ciliated cells: 140.9;Club cells: 130.0;Ionocytes: 89.1;Muller glia cells: 57.7;Oligodendrocyte precursor cells: 157.1;Salivary duct cells: 111.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.9;liver cancer: 10.6" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 109.4;Erythroid cells: 30.7;Spermatocytes: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 52: Non-specific - Cell proliferation" 3 Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 79.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 436.0;Distal tubular cells: 627.0;Proximal enterocytes: 543.8;Proximal tubular cells: 725.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" CISD2 "ERIS, Miner1, NAF-1, WFS2, ZCD2" ENSG00000145354 "CDGSH iron sulfur domain 2" Q8N5K1 4 102868974-102892807 "Disease related genes, Human disease related genes, Predicted membrane proteins" Autophagy "Deafness, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015914 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Plasma cells - Protein processing" 58 "Endoplasmic reticulum" "HPA015914: AB_1846794" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (6.54e-3)" "unprognostic (8.02e-2)" "unprognostic (2.78e-2)" "unprognostic (3.56e-2)" "unprognostic (1.17e-3)" "unprognostic (3.48e-3)" "unprognostic (9.12e-3)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" CKAP4 "CLIMP-63, ERGIC-63, P63" ENSG00000136026 "Cytoskeleton associated protein 4" Q07065 12 106237881-106304279 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 171.2;Plasma cells: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 107.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 107.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000278, HPA000792" Enhanced NA NA 560000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "HPA000278: AB_1078527, HPA000792: AB_1078526" "unprognostic (5.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (7.13e-2)" "unprognostic (2.44e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (6.61e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (5.02e-2)" "unprognostic (9.66e-3)" "unprognostic (1.95e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.20e-3)" "unprognostic (6.97e-2)" "unprognostic (1.29e-2)" "unprognostic (3.66e-2)" CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 384.4;Hofbauer cells: 290.4;Langerhans cells: 258.0;Spermatocytes: 267.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1394.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA062779 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 30: Granulocytes - Unknown function" 1 Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" CKLF-CMTM1 ENSG00000254788 "CKLF-CMTM1 readthrough" 16 66552587-66579135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 5.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Early spermatids: 1.5;Late spermatids: 7.0;Sertoli cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA017136 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: T-cells - T-cell receptor" "HPA017136: AB_1846992" "unprognostic (9.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (1.66e-2)" "unprognostic (2.19e-2)" "unprognostic (9.65e-2)" "unprognostic (5.90e-3)" "unprognostic (3.16e-2)" "unprognostic (1.73e-1)" "unprognostic (9.69e-2)" "unprognostic (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (2.98e-2)" "unprognostic (7.51e-2)" "unprognostic (4.45e-2)" "unprognostic (2.12e-1)" "unprognostic (1.44e-1)" CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 113.7;skin 1: 86.4;vagina: 51.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 123.9;Basal respiratory cells: 50.8;Basal squamous epithelial cells: 62.7;Club cells: 62.1;Squamous epithelial cells: 183.6;Suprabasal keratinocytes: 212.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 24.6;Esophageal cancer: 13.5;Gallbladder cancer: 13.2;head and neck cancer: 29.1" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Transport NA NA 96000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 363.5;intestine: 249.8" "Cell type enhanced" "Detected in some" "Club cells: 70.9;Distal enterocytes: 299.7;Paneth cells: 118.9;Squamous epithelial cells: 192.5;Suprabasal keratinocytes: 97.4" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bladder cancer: 10.1" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" Transport NA NA 150000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108881885-108963527 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA009087: AB_1078532, HPA013210: AB_1846895" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.45e-1)" "unprognostic (5.30e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (7.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-1)" "unprognostic (4.68e-3)" "unprognostic (9.65e-2)" CLCN2 "ClC-2, CLC2, EJM6" ENSG00000114859 "Chloride voltage-gated channel 2" P51788 3 184346185-184361650 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 17.2;Distal enterocytes: 76.3;Proximal enterocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009397, HPA014545, HPA024108" Approved Approved Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Cytosol "CAB009397: AB_2079256, HPA014545: AB_1846881, HPA024108: AB_1846883" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (6.48e-2)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (4.67e-8)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.19e-1)" "unprognostic (4.40e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (1.35e-1)" CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 57: Platelets - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2;retina: 36.7;skeletal muscle: 43.4;tongue: 32.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 74.0;Cone photoreceptor cells: 142.7;Excitatory neurons: 44.1;Horizontal cells: 57.9;Inhibitory neurons: 51.7;Oligodendrocytes: 71.3;Oocytes: 44.8;Rod photoreceptor cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.7;memory B-cell: 1.0;naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 23.1;kidney: 44.6;liver: 16.4" "Cell type enhanced" "Detected in many" "dendritic cells: 49.2;Microglial cells: 44.7" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" CLCN6 "CLC-6, KIAA0046" ENSG00000011021 "Chloride voltage-gated channel 6" P51797 1 11806096-11848079 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.0;Horizontal cells: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032097 Approved Uncertain "Plasma membrane,Cytosol" No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 68: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA032097: AB_10670827" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-1)" "unprognostic (8.83e-2)" "unprognostic (2.08e-1)" "unprognostic (3.84e-3)" "unprognostic (1.51e-3)" "unprognostic (6.49e-2)" "unprognostic (7.76e-2)" "unprognostic (6.61e-3)" "unprognostic (1.71e-3)" "unprognostic (3.44e-1)" "unprognostic (2.13e-2)" "unprognostic (6.91e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" CLCN7 "CLC-7, CLC7, OPTA2, PPP1R63" ENSG00000103249 "Chloride voltage-gated channel 7" P51798 16 1444934-1475077 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 77.3" "Cancer enhanced" "Detected in all" "melanoma: 42.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043019, HPA043586" Supported NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 12 "HPA043019: AB_10964727, HPA043586: AB_10965322" "unprognostic (2.69e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.23e-4)" "unprognostic (1.59e-2)" "unprognostic (1.29e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.41e-2)" "unprognostic (3.98e-1)" "unprognostic (3.49e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (2.80e-1)" "unprognostic (2.54e-1)" CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 334.2" "Cell type enriched" "Detected in some" 7 "Late spermatids: 216.3" "Group enriched" "Detected in some" 7 "renal cancer: 4.4;thyroid cancer: 1.6" "Group enriched" "Detected in some" 7 "cerebellum: 3.9;choroid plexus: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 7.5" "Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" HPA057717 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (4.02e-1)" "unprognostic (2.76e-3)" "unprognostic (8.20e-2)" "unprognostic (6.16e-2)" "unprognostic (1.18e-2)" "unprognostic (6.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (8.13e-3)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (4.37e-3)" "unprognostic (1.28e-1)" CLCNKB hClC-Kb ENSG00000184908 "Chloride voltage-gated channel Kb" P51801 1 16040252-16057311 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 203.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 25.3;Distal tubular cells: 27.7;Early spermatids: 11.9;Ionocytes: 14.7;Late spermatids: 81.0" "Cancer enriched" "Detected in some" 9 "renal cancer: 24.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Testis - Late spermatids" HPA057717 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" "HPA057717: AB_2683509" "unprognostic (9.05e-4)" "unprognostic (1.72e-1)" "unprognostic (2.41e-2)" "unprognostic (2.68e-3)" "unprognostic (1.44e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-4)" "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.27e-7)" "unprognostic (2.04e-2)" "unprognostic (4.62e-1)" "unprognostic (1.78e-2)" "unprognostic (5.14e-2)" CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 300.6;skin 1: 279.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.1;Basal prostatic cells: 240.2;Basal respiratory cells: 208.9;Basal squamous epithelial cells: 208.8;Salivary duct cells: 238.0;Secretory cells: 288.0;Squamous epithelial cells: 291.7;Suprabasal keratinocytes: 478.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "choroid plexus: 43.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 33.6" "CAB002602, HPA048319" Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 90.0;kidney: 131.4;pancreas: 210.3;salivary gland: 88.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 195.9;Cholangiocytes: 366.3;Ductal cells: 407.3;Glandular and luminal cells: 268.3;Ionocytes: 353.1;Oocytes: 322.8;Proximal tubular cells: 231.5;Secretory cells: 194.7;Serous glandular cells: 193.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 67.6" "Liver - Cholangiocyte, Skin - Eccrine sweat gland cells, Testis - Spermatocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 "CAB012969: AB_2533386, HPA042348: AB_2677955" "unprognostic (6.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.35e-1)" "unprognostic (4.60e-2)" "unprognostic (4.73e-2)" "unprognostic (2.46e-3)" "unprognostic (6.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.91e-3)" "unprognostic (2.59e-3)" "unprognostic (7.93e-2)" "prognostic favorable (7.46e-5)" "unprognostic (1.11e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.13e-4)" "unprognostic (4.75e-3)" CLDN11 "OSP, OTM" ENSG00000013297 "Claudin 11" O75508 3 170418868-170454733 "Disease related genes, Human disease related genes, Predicted membrane proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 297.7;ovary: 92.4;testis: 113.7" "Cell type enhanced" "Detected in many" "Leydig cells: 100.9;Oligodendrocytes: 367.2;Ovarian stromal cells: 168.0;Sertoli cells: 304.6" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 29.3" "Testis - Sertoli cells" "Region enriched" "Detected in all" 5 "white matter: 2085.3" "Low region specificity" "Detected in all" "CAB009789, HPA013166, HPA013657" Enhanced Approved "Lipid droplets,Cell Junctions" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 6: Ovarian stromal cells - Transcription" 9 "Lipid droplets, Cell Junctions" "CAB009789: AB_639330, HPA013166: AB_1854821, HPA013657: " "prognostic favorable (6.31e-4)" "unprognostic (3.18e-1)" "unprognostic (2.32e-2)" "unprognostic (5.28e-4)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (5.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.48e-2)" "unprognostic (8.70e-11)" "unprognostic (2.50e-3)" "unprognostic (1.93e-1)" "unprognostic (6.68e-3)" "unprognostic (2.29e-1)" CLDN12 ENSG00000157224 "Claudin 12" P56749 7 90383721-90513402 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026945 Approved NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Early spermatids - Spermatogenesis" "HPA026945: AB_10603786" "unprognostic (1.45e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (3.84e-2)" "unprognostic (4.87e-2)" "unprognostic (7.28e-2)" "unprognostic (1.86e-2)" "unprognostic (6.47e-2)" "unprognostic (3.41e-2)" "unprognostic (3.67e-1)" "unprognostic (9.06e-2)" "unprognostic (1.67e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (7.66e-2)" "unprognostic (2.37e-1)" "unprognostic (9.49e-2)" "unprognostic (1.30e-1)" CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "kidney: 13.4;liver: 38.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.8;Distal tubular cells: 9.2;Ductal cells: 12.0;Exocrine glandular cells: 4.6;Glandular and luminal cells: 4.7;Hepatocytes: 18.6" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 7.9" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054707 Uncertain Vesicles NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" CLDN16 "HOMG3, PCLN1" ENSG00000113946 "Claudin 16" Q9Y5I7 3 190322541-190412138 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "kidney: 61.3" "Cell type enriched" "Detected in some" 10 "Distal tubular cells: 119.9" "Group enriched" "Detected in many" 15 "ovarian cancer: 39.8;thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "ovarian cancer: 120.3;Uterine cancer: 175.0" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA056020 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" "HPA056020: AB_2683011" "unprognostic (5.01e-2)" "unprognostic (7.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (6.06e-4)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (3.31e-1)" "unprognostic (4.20e-1)" "unprognostic (2.76e-3)" "unprognostic (3.70e-1)" "unprognostic (1.96e-1)" "unprognostic (5.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" CLDN17 "MGC126552, MGC126554" ENSG00000156282 "Claudin 17" P56750 21 30165565-30166805 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 2.3;esophagus: 6.0;salivary gland: 6.2;vagina: 7.0" "Group enriched" "Detected in some" 4 "Early spermatids: 6.5;Suprabasal keratinocytes: 5.7" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045903 Enhanced NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA045903: AB_2679491" "unprognostic (2.41e-1)" CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "lung: 244.4;stomach 1: 706.2" "Group enriched" "Detected in some" 32 "Alveolar cells type 1: 661.9;Alveolar cells type 2: 361.3;Gastric mucus-secreting cells: 1092.4" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;pancreatic cancer: 12.4" "Lung - Alveolar cells type 1, Stomach - Gastric mucous cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 17: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" CLDN19 ENSG00000164007 "Claudin 19" Q8N6F1 1 42733093-42740254 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 12.5;kidney: 38.1;placenta: 9.4" "Cell type enriched" "Detected in some" 17 "Extravillous trophoblasts: 264.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Region enriched" "Detected in many" 14 "choroid plexus: 43.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;testis cancer: 3.2" "Kidney - Ascending Loop of Henle cells" "Region enhanced" "Detected in many" "olfactory bulb: 5.4" "Region enriched" "Detected in all" 5 "spinal cord: 89.7" HPA014412 Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA014412: " "unprognostic (6.23e-4)" "unprognostic (1.80e-1)" "unprognostic (1.85e-6)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-1)" "unprognostic (9.45e-2)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (7.22e-2)" "unprognostic (8.76e-3)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.29e-3)" CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 194.7;gallbladder: 98.1;kidney: 159.3;seminal vesicle: 87.0" "Cell type enhanced" "Detected in some" "Ductal cells: 75.9;Exocrine glandular cells: 36.3;Hepatocytes: 25.7;Proximal enterocytes: 31.3;Proximal tubular cells: 88.4" "Group enriched" "Detected in many" 5 "colorectal cancer: 53.3;liver cancer: 24.6;pancreatic cancer: 48.5;renal cancer: 87.2;stomach cancer: 30.5" "Region enriched" "Detected in many" 13 "choroid plexus: 243.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 127.7;Kidney cancer: 98.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Low region specificity" "Detected in many" "CAB002609, HPA051548" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 16 "Nucleoplasm, Cell Junctions" "CAB002609: , HPA051548: AB_2681530" "unprognostic (2.31e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-2)" "unprognostic (6.07e-2)" "unprognostic (7.47e-3)" "unprognostic (2.24e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (8.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "prognostic favorable (1.70e-4)" "unprognostic (9.76e-2)" CLDN20 ENSG00000171217 "Claudin 20" P56880 6 155264013-155276548 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.3;Excitatory neurons: 1.7;granulocytes: 1.0;Inhibitory neurons: 1.6;Oligodendrocytes: 1.9;Schwann cells: 1.2;Sertoli cells: 2.7;Suprabasal keratinocytes: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" HPA073105 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 40: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "Golgi apparatus, Plasma membrane" Cytosol "HPA073105: " "unprognostic (3.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (2.84e-1)" "unprognostic (4.04e-2)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (1.67e-1)" "unprognostic (5.22e-2)" "unprognostic (6.26e-2)" "unprognostic (6.40e-2)" "unprognostic (7.33e-3)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (3.29e-2)" "unprognostic (2.05e-1)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.9;stomach 1: 15.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 337.6;Gastric mucus-secreting cells: 61.9;Paneth cells: 183.6;Proximal enterocytes: 99.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 4.6" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" CLDN25 ENSG00000228607 "Claudin 25" C9JDP6 11 113779796-113780485 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053555 Uncertain NA NA "Cluster 50: Lymphoma - Unknown function" "HPA053555: AB_2682186" "unprognostic (1.02e-2)" "unprognostic (3.22e-1)" CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 255.8;thyroid gland: 112.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3382.2;Enteroendocrine cells: 1232.2;Glandular and luminal cells: 1710.6;Intestinal goblet cells: 1891.4;Paneth cells: 2536.5;Proximal enterocytes: 3236.9;Undifferentiated cells: 1191.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Region enriched" "Detected in all" 8 "choroid plexus: 81.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 169.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells" "Region enhanced" "Detected in single" "basal ganglia: 1.5" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 296.4;urinary bladder: 291.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2807.8;Glandular and luminal cells: 2344.4;Ionocytes: 1646.0;Paneth cells: 2199.5;Proximal enterocytes: 1639.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 992.2" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 14 "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 425.6;breast: 407.2;choroid plexus: 418.8;lung: 386.5" "Group enriched" "Detected in many" 12 "Adipocytes: 2773.0;Endothelial cells: 835.9;Lymphatic endothelial cells: 1261.5" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 19.0;naive CD4 T-cell: 4.8;neutrophil: 5.9" "Group enriched" "Detected in many" 29 "granulocytes: 19.0;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;cervical cancer: 13.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 33 "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 331.7;intestine: 331.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1489.3;Intestinal goblet cells: 761.2;Paneth cells: 878.8;Proximal enterocytes: 1331.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 61 Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 66.8;intestine: 49.3;kidney: 66.8;salivary gland: 39.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 28.3;Collecting duct cells: 194.5;Distal enterocytes: 89.3;Mucus glandular cells: 27.9;Salivary duct cells: 37.1" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.6;prostate cancer: 8.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" 8 "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" CLDN9 ENSG00000213937 "Claudin 9" O95484 16 3012923-3014505 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.4;pituitary gland: 24.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.3;Ciliated cells: 13.9;Ductal cells: 8.7;Secretory cells: 8.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.3" HPA076613 Supported "Vesicles,Cell Junctions" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 17 "Cell Junctions" Vesicles "HPA076613: AB_2686808" "unprognostic (7.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.24e-6)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "unprognostic (8.97e-3)" "unprognostic (4.51e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.55e-2)" CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 13 "brain: 1378.2" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 535.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 15: Non-specific - Mixed function" 3 Nucleoplasm "Nucleoli, Cytosol" "HPA029841: AB_10600658" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.13e-2)" "unprognostic (8.50e-2)" "unprognostic (9.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.43e-3)" "unprognostic (4.08e-2)" "unprognostic (3.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.84e-6)" "unprognostic (5.73e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.51e-1)" CLDND2 MGC33839 ENSG00000160318 "Claudin domain containing 2" Q8NHS1 19 51367098-51369003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 43.7" "Cell type enriched" "Detected in many" 16 "Early spermatids: 457.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056971 Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: RS4;11 - Unknown function" "Cluster 18: Early spermatids - Unknown function" 24 Nucleoplasm "HPA056971: AB_2683294" "unprognostic (2.86e-1)" "unprognostic (4.29e-5)" "unprognostic (2.29e-2)" "unprognostic (3.40e-2)" "unprognostic (1.19e-1)" "unprognostic (9.42e-2)" "unprognostic (5.74e-3)" "unprognostic (1.79e-1)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.25e-3)" "unprognostic (1.13e-2)" "unprognostic (1.94e-9)" "unprognostic (4.00e-2)" "unprognostic (3.95e-1)" "unprognostic (1.85e-1)" "unprognostic (8.70e-2)" CLEC10A "CD301, CLECSF13, CLECSF14, HML, HML2" ENSG00000132514 "C-type lectin domain containing 10A" Q8IUN9 17 7074537-7080307 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Endocytosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.5" "Cell type enriched" "Detected in some" 5 "Langerhans cells: 1016.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 12 "myeloid DC: 466.5" "Lineage enriched" "Detected in many" 12 "dendritic cells: 466.5" "Not detected" "Not detected" "Skeletal muscle - Macrophages" "Not detected" "Not detected" HPA021937 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" 22 "HPA021937: AB_1846905" "unprognostic (3.96e-3)" "unprognostic (1.71e-3)" "unprognostic (2.95e-2)" "unprognostic (2.04e-3)" "unprognostic (4.54e-2)" "prognostic favorable (1.26e-5)" "unprognostic (1.07e-1)" "prognostic favorable (9.24e-4)" "unprognostic (2.70e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.12e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (3.23e-1)" "unprognostic (3.65e-1)" CLEC12A "CD371, CLL-1, DCAL-2, MICL" ENSG00000172322 "C-type lectin domain family 12 member A" Q5QGZ9 12 9951316-9995694 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.8;lymphoid tissue: 21.6" "Cell type enhanced" "Detected in some" "granulocytes: 40.1;Hofbauer cells: 63.8;Kupffer cells: 96.9;Macrophages: 119.6;monocytes: 183.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 203.3" "Group enriched" "Detected in many" 37 "dendritic cells: 72.7;granulocytes: 203.3;monocytes: 137.1" "Cancer enriched" "Detected in some" 16 "Leukemia: 21.6" "Stomach - Macrophages" "Region enriched" "Detected in single" 7 "basal ganglia: 6.2" "Low region specificity" "Detected in single" HPA048515 Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA048515: AB_2680425" "unprognostic (4.74e-2)" "unprognostic (6.06e-3)" "unprognostic (7.76e-2)" "unprognostic (6.88e-2)" "unprognostic (2.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (3.29e-1)" "unprognostic (1.44e-2)" "unprognostic (1.70e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-3)" "unprognostic (9.67e-3)" "unprognostic (7.43e-2)" "unprognostic (3.78e-2)" "prognostic favorable (9.33e-4)" CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 379.0;Endothelial cells: 326.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Leukemia: 8.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 12 "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" CLEC1B "CLEC-2, CLEC2" ENSG00000165682 "C-type lectin domain family 1 member B" Q9P126 12 9985642-10013424 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 77.6" "Cell type enhanced" "Detected in some" "Endothelial cells: 23.8;Erythroid cells: 10.5;Fibroblasts: 105.3;Kupffer cells: 42.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.6;monocytes: 5.1" "Group enriched" "Detected in some" 24 "Leukemia: 5.3;Myeloma: 4.4;Rhabdoid: 4.0" "Liver - Sinusoid Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA051108 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA051108: " "unprognostic (2.03e-1)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-2)" "unprognostic (7.71e-2)" "unprognostic (4.98e-2)" "unprognostic (1.58e-1)" "unprognostic (8.13e-2)" "unprognostic (1.49e-3)" "unprognostic (1.46e-2)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (2.91e-2)" CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 56.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Melanocytes: 3.4;Oligodendrocytes: 2.1;Suprabasal keratinocytes: 17.9" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Leukemia: 8.3" "Skin - Keratinocyte (other)" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 82: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" CLEC2D "CLAX, LLT1, OCIL" ENSG00000069493 "C-type lectin domain family 2 member D" Q9UHP7 12 9664969-9699553 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "B-cells: 93.4;Early spermatids: 85.2;NK-cells: 134.1;T-cells: 205.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "gdT-cell: 188.8;MAIT T-cell: 114.9;memory B-cell: 95.7;memory CD4 T-cell: 184.0;memory CD8 T-cell: 208.9;naive B-cell: 128.1;naive CD4 T-cell: 193.2;naive CD8 T-cell: 223.9;T-reg: 175.8" "Group enriched" "Detected in all" 11 "B-cells: 128.1;T-cells: 223.9" "Group enriched" "Detected in many" 6 "Leukemia: 19.5;lymphoma: 70.3;Myeloma: 19.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - T-cells, Thyroid - T-cells" "HPA017649, HPA047584" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus" "HPA017649: AB_1846912, HPA047584: " "unprognostic (1.09e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (1.29e-1)" "unprognostic (2.77e-4)" "unprognostic (4.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.85e-11)" "unprognostic (1.17e-1)" "unprognostic (2.70e-1)" "unprognostic (3.44e-1)" "prognostic favorable (1.68e-7)" CLEC2L FLJ32986 ENSG00000236279 "C-type lectin domain family 2 member L" P0C7M8 7 139523685-139544985 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 44.5;parathyroid gland: 13.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 49.9;Horizontal cells: 41.5;Inhibitory neurons: 47.6" "Cancer enhanced" "Detected in many" "testis cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.4;Myeloma: 5.3" "Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045050 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" "HPA045050: AB_10965839" "unprognostic (1.18e-2)" "unprognostic (2.42e-1)" "unprognostic (7.20e-4)" "unprognostic (1.24e-2)" "unprognostic (1.33e-2)" "unprognostic (6.17e-2)" "unprognostic (2.29e-6)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (6.73e-2)" "unprognostic (2.68e-1)" "unprognostic (8.31e-2)" "unprognostic (7.94e-4)" "unprognostic (3.57e-3)" "unprognostic (4.03e-2)" "unprognostic (8.42e-3)" "unprognostic (3.02e-2)" CLEC4A "CD367, CLECSF6, DCIR, DDB27, hDCIR" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 21.3;lymphoid tissue: 26.1" "Group enriched" "Detected in some" 4 "Hofbauer cells: 14.1;Kupffer cells: 28.8;Langerhans cells: 31.2;Macrophages: 35.2;monocytes: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 227.9;classical monocyte: 333.0;intermediate monocyte: 198.7;myeloid DC: 328.2;neutrophil: 300.4;non-classical monocyte: 130.7" "Group enriched" "Detected in all" 13 "dendritic cells: 328.2;granulocytes: 300.4;monocytes: 333.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" "HPA007842: AB_1078534" "unprognostic (9.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.13e-2)" "unprognostic (2.69e-1)" "unprognostic (9.34e-2)" "unprognostic (5.49e-2)" "unprognostic (8.22e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.42e-3)" "unprognostic (1.42e-1)" "unprognostic (1.35e-2)" "unprognostic (3.05e-1)" "unprognostic (9.79e-2)" CLEC4C "BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL" ENSG00000198178 "C-type lectin domain family 4 member C" Q8WTT0 12 7729383-7751605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.3" "Group enriched" "Detected in some" 16 "dendritic cells: 194.6;Oocytes: 87.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 16 "plasmacytoid DC: 469.2" "Lineage enriched" "Detected in many" 16 "dendritic cells: 469.2" "Not detected" "Not detected" HPA029432 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA029432: AB_10601259" "unprognostic (3.55e-3)" "unprognostic (3.01e-2)" "unprognostic (1.03e-1)" "unprognostic (3.70e-2)" "unprognostic (7.37e-5)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-2)" "unprognostic (6.98e-2)" "unprognostic (1.39e-1)" "unprognostic (1.88e-3)" "unprognostic (2.82e-2)" "unprognostic (3.18e-3)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" CLEC4E "CLECSF9, MINCLE" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;lymphoid tissue: 51.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 39.5;Hofbauer cells: 52.8;Kupffer cells: 170.0;Macrophages: 104.7;monocytes: 203.2" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 129.3;neutrophil: 451.9" "Group enriched" "Detected in many" 17 "granulocytes: 451.9;monocytes: 129.3" "Group enriched" "Detected in some" 8 "Kidney cancer: 30.8;ovarian cancer: 9.6" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 3 "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Langerhans cells: 2.7;Macrophages: 3.6;monocytes: 13.9;Rod photoreceptor cells: 9.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cancer enhanced" "Detected in some" "Bone cancer: 1.5;lymphoma: 3.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Retina - Visual perception" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" Cytosol "HPA056101: " "unprognostic (8.14e-3)" "unprognostic (3.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (4.91e-2)" "unprognostic (5.41e-2)" "unprognostic (3.66e-2)" "unprognostic (2.07e-2)" "unprognostic (9.29e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-2)" "unprognostic (9.59e-2)" "unprognostic (2.44e-1)" CLEC4G "LSECTIN, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728957-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;liver: 52.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1.9;Inhibitory neurons: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.2" "Group enriched" "Detected in many" 4 "dendritic cells: 15.2;monocytes: 18.8" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Sinusoid Endothelial cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 9 "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" CLEC4M "CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN" ENSG00000104938 "C-type lectin domain family 4 member M" Q9H2X3 19 7763210-7769605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 60.8;lymphoid tissue: 16.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 21.8;Fibroblasts: 41.6;Granulosa cells: 32.9;Kupffer cells: 19.0;Sertoli cells: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033689, CAB033691, HPA042661" Supported "Intracellular and membrane" Receptor NA NA 3400000 "Cluster 31: Liver - Plasma proteins" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "CAB033689: AB_831088, CAB033691: AB_2081354, HPA042661: AB_2678101" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.00e-1)" "unprognostic (1.71e-2)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (6.58e-2)" "unprognostic (1.27e-1)" "unprognostic (4.58e-3)" "unprognostic (4.60e-2)" "unprognostic (5.15e-2)" "unprognostic (1.43e-1)" CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 40.8" "Group enriched" "Detected in some" 8 "Hofbauer cells: 33.9;Langerhans cells: 93.9;Macrophages: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Cancer enriched" "Detected in single" 128 "Leukemia: 12.7" "Kidney - Macrophages, Prostate - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.4;testis: 110.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 443.6;Early spermatids: 214.2;Muller glia cells: 147.1;Prostatic glandular cells: 104.8;Spermatocytes: 395.1" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 40.4" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 44: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 60: Prostate cancer - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" CLIP4 "FLJ21069, RSNL2" ENSG00000115295 "CAP-Gly domain containing linker protein family member 4" Q8N3C7 2 29097705-29199777 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 69.4" "Cell type enhanced" "Detected in many" "Early spermatids: 130.2;Inhibitory neurons: 137.1;Late spermatids: 130.5;monocytes: 140.5;Oligodendrocyte precursor cells: 122.2;Oligodendrocytes: 230.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 24.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043366, HPA056246" Uncertain Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 10 Vesicles "HPA043366: AB_10963051, HPA056246: AB_2683078" "unprognostic (1.97e-2)" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (2.47e-3)" "unprognostic (3.64e-1)" "unprognostic (6.82e-2)" "unprognostic (1.15e-2)" "unprognostic (8.82e-3)" "unprognostic (3.62e-1)" "unprognostic (4.32e-2)" "unprognostic (2.73e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.59e-3)" "unprognostic (6.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.99e-2)" CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864691 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 80: Non-specific - Transcription" 3 "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: AB_2684753" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.28e-4)" CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 169.4;Late spermatids: 574.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" No No "Cluster 24: Non-specific - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 11: Late spermatids - Unknown function" 6 "Actin filaments" "HPA043746: AB_2678650" "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" CLMN "FLJ12383, KIAA0500, KIAA1188" ENSG00000165959 Calmin Q96JQ2 14 95181940-95319908 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.9" "Cell type enhanced" "Detected in many" "Late spermatids: 320.7;Oligodendrocytes: 389.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012634 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nuclear bodies" Cytosol "HPA012634: AB_1846973" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (4.20e-2)" "unprognostic (6.07e-2)" "unprognostic (8.88e-2)" "unprognostic (4.31e-1)" "unprognostic (4.18e-2)" "unprognostic (7.24e-2)" "unprognostic (8.31e-2)" "unprognostic (2.64e-1)" "unprognostic (1.29e-3)" "unprognostic (3.09e-2)" "prognostic favorable (2.68e-7)" "unprognostic (8.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (9.91e-3)" CLN3 "BTN1, BTS, JNCL" ENSG00000188603 "CLN3 lysosomal/endosomal transmembrane protein, battenin" Q13286 16 28474111-28495575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063280 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: T-cells - T-cell receptor" 3 "HPA063280: AB_2684975" "unprognostic (2.38e-3)" "unprognostic (2.41e-2)" "unprognostic (7.06e-2)" "unprognostic (8.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-2)" "unprognostic (6.38e-3)" "unprognostic (8.16e-2)" "unprognostic (6.27e-2)" "unprognostic (5.26e-1)" "unprognostic (9.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-2)" CLN6 "FLJ20561, HsT18960, nclf" ENSG00000128973 "CLN6 transmembrane ER protein" Q9NWW5 15 68206992-68257211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066046, HPA066759" Approved Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 21 "Endoplasmic reticulum" "Nucleoli, Vesicles" "HPA066046: AB_2685604, HPA066759: " "unprognostic (1.01e-1)" "unprognostic (1.54e-3)" "unprognostic (7.01e-2)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (3.08e-1)" "unprognostic (2.24e-2)" "unprognostic (5.07e-2)" "unprognostic (2.40e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-1)" "unprognostic (6.78e-2)" CLPTM1 ENSG00000104853 "CLPTM1 regulator of GABA type A receptor forward trafficking" O96005 19 44954585-44993341 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068767 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 "Endoplasmic reticulum" "HPA068767: " "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (4.07e-1)" "unprognostic (2.19e-1)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.94e-1)" "unprognostic (5.93e-2)" "unprognostic (6.60e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (2.62e-1)" "unprognostic (1.02e-2)" "unprognostic (3.30e-1)" "unprognostic (2.56e-1)" "unprognostic (7.46e-2)" "unprognostic (1.59e-1)" CLPTM1L "CRR9, FLJ14400" ENSG00000049656 "CLPTM1 like" Q96KA5 5 1317752-1345099 "Predicted membrane proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 246.9;Plasma cells: 206.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014791 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 "Endoplasmic reticulum" "HPA014791: AB_1847250" "unprognostic (2.92e-2)" "unprognostic (1.34e-1)" "unprognostic (9.53e-2)" "unprognostic (8.43e-2)" "unprognostic (5.16e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (5.47e-3)" "unprognostic (9.14e-3)" "unprognostic (1.06e-1)" "unprognostic (5.77e-3)" "unprognostic (8.57e-2)" "unprognostic (4.92e-2)" "unprognostic (4.54e-2)" "unprognostic (4.17e-2)" CLRN2 DFNB117 ENSG00000249581 "Clarin 2" A0PK11 4 17515165-17527104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA042407 Uncertain NA NA 10 "HPA042407: AB_10806237" CLRN3 "MGC32871, TMEM12, USH3AL1" ENSG00000180745 "Clarin 3" Q8NCR9 10 127877841-127892941 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 86.6;kidney: 42.3;liver: 77.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 95.1;Enteroendocrine cells: 53.4;Hepatocytes: 40.4;Intestinal goblet cells: 81.5;Paneth cells: 77.2;Proximal enterocytes: 153.7;Proximal tubular cells: 55.2;Undifferentiated cells: 34.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.3;renal cancer: 30.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 37.8;Gastric cancer: 20.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014482 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA014482: AB_2082885" "unprognostic (7.34e-3)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-1)" "unprognostic (5.08e-2)" "unprognostic (2.62e-1)" "unprognostic (6.22e-2)" "unprognostic (4.67e-1)" "unprognostic (8.86e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.74e-1)" "unprognostic (2.89e-3)" "unprognostic (3.00e-2)" CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 406.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 86000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 28: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA012412: AB_1846981, HPA077705: " "unprognostic (4.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.43e-1)" "unprognostic (9.79e-2)" "unprognostic (1.63e-1)" "unprognostic (2.44e-3)" "unprognostic (3.07e-2)" "unprognostic (2.54e-1)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "prognostic favorable (4.10e-7)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (4.05e-2)" "unprognostic (4.72e-2)" CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4;ovary: 40.5" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 532.8" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 20.0;testis cancer: 39.3" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15675012 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 468.7" "Cell type enriched" "Detected in many" 22 "Proximal tubular cells: 673.6" "Cancer enriched" "Detected in many" 35 "renal cancer: 106.2" "Region enriched" "Detected in all" 14 "choroid plexus: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 3 "Endoplasmic reticulum, Vesicles" "HPA048543: AB_2680436" "unprognostic (1.27e-1)" "unprognostic (4.77e-2)" "unprognostic (2.45e-2)" "unprognostic (2.66e-2)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.65e-4)" "unprognostic (1.05e-2)" "unprognostic (3.03e-1)" "prognostic favorable (6.78e-9)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-2)" CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99909459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.5" "Cell type enhanced" "Detected in all" "Astrocytes: 80.5;Distal tubular cells: 119.9;Hepatocytes: 111.7;Proximal tubular cells: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 7300 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 19: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.4" "Cell type enhanced" "Detected in some" "dendritic cells: 18.6;Hofbauer cells: 28.9;Kupffer cells: 51.1;Macrophages: 29.6;Microglial cells: 37.6;NK-cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.6;plasmacytoid DC: 18.2" "Group enriched" "Detected in many" 22 "dendritic cells: 18.2;monocytes: 14.6;T-cells: 7.1" "Low cancer specificity" "Detected in some" "Breast - Macrophages, Heart muscle - Fibroblasts, Liver - Kupffer cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" CMKLR2 GPR1 ENSG00000183671 "Chemerin chemokine-like receptor 2" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.4" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 14.8;Granulosa cells: 6.3;Lymphatic endothelial cells: 26.1;Oocytes: 4.4;Ovarian stromal cells: 4.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Region enriched" "Detected in many" 12 "choroid plexus: 35.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" CMTM1 "CKLFH, CKLFH1a, CKLFSF1" ENSG00000089505 "CKLF like MARVEL transmembrane domain containing 1" Q8IZ96 16 66566393-66579137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 30.4" "Group enriched" "Detected in some" 5 "Early spermatids: 56.6;Late spermatids: 111.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.8;eosinophil: 6.2;neutrophil: 7.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA013801, HPA017136" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Nucleoplasm "HPA013801: AB_1846990, HPA017136: AB_1846992" "unprognostic (2.37e-2)" "unprognostic (7.48e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-1)" "unprognostic (3.81e-1)" "unprognostic (5.32e-2)" "unprognostic (2.97e-3)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (2.47e-2)" "unprognostic (1.56e-4)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (3.49e-1)" CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 101.7;Extravillous trophoblasts: 261.5;Hofbauer cells: 120.2;Sertoli cells: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 4: Extravillous trophoblasts - Unknown function" 19 Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 79.4;Distal enterocytes: 77.6;Excitatory neurons: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 253.1" "Cell type enhanced" "Detected in some" "Melanocytes: 20.6;Muller glia cells: 27.7;Oligodendrocyte precursor cells: 19.3;Oligodendrocytes: 98.9;Schwann cells: 77.7" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;skin cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Skin - Smooth muscle cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 38 "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 981.7;monocytes: 1008.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Monocytes - Innate immune response" 17 Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" CMTM7 "CKLFSF7, FLJ30992" ENSG00000153551 "CKLF like MARVEL transmembrane domain containing 7" Q96FZ5 3 32391698-32483067 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 132.0;Kupffer cells: 106.8;Langerhans cells: 120.0;monocytes: 165.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077409 Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 14: Langerhans cells - Innate immune response" 39 "Plasma membrane" "HPA077409: AB_2686838" "unprognostic (2.27e-3)" "unprognostic (3.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.15e-1)" "unprognostic (5.42e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (3.03e-2)" "unprognostic (3.92e-2)" "unprognostic (2.60e-1)" "unprognostic (6.55e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.00e-6)" "unprognostic (5.86e-2)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (3.12e-2)" CMTM8 CKLFSF8 ENSG00000170293 "CKLF like MARVEL transmembrane domain containing 8" Q8IZV2 3 32238679-32370321 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 46.2" "Cell type enhanced" "Detected in many" "Adipocytes: 90.2;Cytotrophoblasts: 107.8;Syncytiotrophoblasts: 118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055077, HPA073258" Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 17: Breast glandular cells - Lactation" 3 Nucleoplasm "HPA055077: AB_2682691, HPA073258: AB_2686591" "unprognostic (9.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-1)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (9.46e-2)" "unprognostic (5.67e-2)" "unprognostic (8.85e-2)" "unprognostic (1.29e-1)" "unprognostic (7.59e-2)" "unprognostic (2.56e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 55: Non-specific - Transcription" "Cell Junctions" "Nuclear speckles" "HPA041700: AB_2677623, HPA048265: AB_2680334" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favorable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" CNEP1R1 "C16orf69, FLJ38101, NEP1-R1, TMEM188" ENSG00000205423 "CTD nuclear envelope phosphatase 1 regulatory subunit 1" Q8N9A8 16 50024410-50037088 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042815, HPA077906" Uncertain Supported Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "HPA042815: AB_10794765, HPA077906: AB_2686868" "unprognostic (4.11e-2)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.43e-3)" "unprognostic (1.80e-1)" "unprognostic (3.42e-2)" "unprognostic (8.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (3.37e-3)" "unprognostic (5.09e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 256.4" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 908.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA076168 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA076168: AB_2686781" "unprognostic (2.68e-2)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.48e-6)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" CNGA2 "CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA" ENSG00000183862 "Cyclic nucleotide gated channel subunit alpha 2" Q16280 X 151734746-151745564 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Olfaction, Sensory transduction, Transport" "Calmodulin-binding, Ion channel, Ligand-gated ion channel" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA015065 Uncertain NA NA "Cluster 11: Neuronal - Sensory perception" "HPA015065: AB_1847034" CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.8;intestine: 4.1;pituitary gland: 9.9;retina: 5.7" "Cell type enriched" "Detected in some" 11 "Cone photoreceptor cells: 34.0" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 1.5" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 22: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "CAB079025: , HPA049378: AB_2732551" "unprognostic (2.34e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-2)" "unprognostic (4.81e-2)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.17e-4)" "unprognostic (4.65e-2)" "unprognostic (1.86e-3)" "unprognostic (2.88e-1)" "unprognostic (3.85e-3)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.71e-2)" CNGA4 "CNCA2, CNG5, CNGB2, OCNC2, OCNCb" ENSG00000132259 "Cyclic nucleotide gated channel subunit alpha 4" Q8IV77 11 6234765-6244479 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Olfaction, Sensory transduction, Transport" "Ion channel, Ligand-gated ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "fallopian tube: 16.7;testis: 5.9" "Cell type enhanced" "Detected in some" "Astrocytes: 8.7;Ciliated cells: 2.2;Early spermatids: 5.2;Excitatory neurons: 2.9;Inhibitory neurons: 2.5;Late spermatids: 4.5;Oligodendrocytes: 2.8" "Cancer enriched" "Detected in single" 6 "endometrial cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA074128 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 47: Astrocytes - Unknown function" "Nucleoplasm, Plasma membrane" "HPA074128: " "unprognostic (1.11e-2)" "unprognostic (4.32e-2)" "unprognostic (2.69e-3)" "prognostic favorable (1.48e-4)" "unprognostic (4.96e-2)" "unprognostic (1.09e-1)" "unprognostic (2.01e-3)" "unprognostic (1.89e-1)" "unprognostic (8.51e-2)" "unprognostic (5.51e-2)" "unprognostic (1.83e-2)" "unprognostic (8.70e-2)" "unprognostic (1.03e-3)" "unprognostic (3.84e-2)" "unprognostic (3.47e-2)" "unprognostic (8.11e-2)" "unprognostic (3.55e-3)" CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "retina: 581.5" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 348.3;Rod photoreceptor cells: 1033.4" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.1" "Colon - Colon enteroendocrine cells, Pancreas - Ductal cells, Skin - Outer root sheath cells" "Region enhanced" "Detected in some" "hypothalamus: 4.5" HPA060355 Approved "Plasma membrane,Cytosol" No NA "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "Plasma membrane" "HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" CNGB3 "ACHM1, ACHM3, RMCH" ENSG00000170289 "Cyclic nucleotide gated channel subunit beta 3" Q9NQW8 8 86553977-86743675 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;retina: 12.1" "Cell type enriched" "Detected in some" 22 "Cone photoreceptor cells: 249.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA057244 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" "HPA057244: AB_2683380" "unprognostic (5.35e-1)" "unprognostic (1.68e-3)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (3.62e-2)" "unprognostic (2.58e-1)" "unprognostic (6.25e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (2.17e-1)" "unprognostic (3.82e-1)" "unprognostic (9.28e-2)" "unprognostic (2.77e-4)" "unprognostic (1.40e-4)" "unprognostic (1.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.84e-1)" CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 64: Non-specific - Ribosome" 21 Vesicles "HPA002544: AB_2081856" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (7.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.50e-1)" "unprognostic (8.93e-3)" "unprognostic (1.47e-1)" "unprognostic (2.71e-3)" "unprognostic (4.78e-2)" "unprognostic (4.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (8.95e-4)" CNIH4 HSPC163 ENSG00000143771 "Cornichon family AMPA receptor auxiliary protein 4" Q9P003 1 224356858-224379459 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 309.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044268 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 15: Non-specific - Mixed function" 2 "HPA044268: AB_10965330" "unprognostic (2.01e-1)" "unprognostic (1.34e-3)" "unprognostic (1.56e-1)" "unprognostic (1.66e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (4.47e-3)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (5.96e-3)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.27e-6)" "unprognostic (3.15e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-3)" "unprognostic (1.63e-2)" CNMD "BRICD3, CHM-I, CHM1, LECT1, MYETS1" ENSG00000136110 Chondromodulin O75829 13 52703264-52739820 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.4;choroid plexus: 12.2;retina: 8.1;salivary gland: 6.5;thyroid gland: 3.2" "Cell type enriched" "Detected in some" 6 "Muller glia cells: 84.1" "Group enriched" "Detected in many" 5 "glioma: 1.5;lung cancer: 6.0;testis cancer: 5.8;thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.1;testis cancer: 1.2" "Pancreas - Beta cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010510 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA 9500 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" "HPA010510: AB_10602021" "unprognostic (7.52e-3)" "unprognostic (1.34e-1)" "unprognostic (7.36e-2)" "unprognostic (1.45e-2)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (2.84e-2)" "unprognostic (2.63e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-1)" CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5;testis: 9.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Early spermatids: 105.9;Excitatory neurons: 67.5;Horizontal cells: 34.6;Inhibitory neurons: 85.8;Late spermatids: 97.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 3 "Plasma membrane, Cytosol" "HPA040408: AB_10793963" "unprognostic (9.04e-4)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-4)" "unprognostic (4.08e-3)" "unprognostic (9.51e-2)" "unprognostic (6.01e-2)" "unprognostic (2.27e-2)" "unprognostic (6.03e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-2)" "unprognostic (2.45e-1)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" CNNM2 ACDP2 ENSG00000148842 "Cyclin and CBS domain divalent metal cation transport mediator 2" Q9H8M5 10 102918294-103090222 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 22.9;parathyroid gland: 30.4" "Cell type enhanced" "Detected in many" "Astrocytes: 57.0;Excitatory neurons: 108.8;Inhibitory neurons: 140.8;Oligodendrocyte precursor cells: 86.8;Oligodendrocytes: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.5" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059954, HPA071631" Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA059954: AB_2684177, HPA071631: AB_2686427" "unprognostic (2.18e-1)" "unprognostic (6.46e-2)" "unprognostic (1.24e-1)" "unprognostic (2.65e-3)" "unprognostic (3.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.93e-1)" "unprognostic (4.80e-2)" "unprognostic (4.51e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.39e-8)" "unprognostic (2.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.65e-3)" "unprognostic (1.56e-1)" CNNM3 ACDP3 ENSG00000168763 "Cyclin and CBS domain divalent metal cation transport mediator 3" Q8NE01 2 96816245-96835382 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016711 Supported Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 59 Cytosol "HPA016711: AB_1847394" "unprognostic (1.50e-2)" "unprognostic (6.96e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.32e-3)" "unprognostic (3.64e-1)" "unprognostic (5.31e-3)" "unprognostic (7.35e-2)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 37.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.2;Distal enterocytes: 76.5;Rod photoreceptor cells: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029844, HPA046577, HPA049664" Approved Uncertain Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 13 Cytosol "HPA029844: , HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" CNPPD1 "C2orf24, CGI-57" ENSG00000115649 "Cyclin Pas1/PHO80 domain containing 1" Q9BV87 2 219171897-219178106 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049303 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" "HPA049303: AB_2680703" "unprognostic (9.24e-2)" "unprognostic (4.12e-2)" "unprognostic (1.09e-1)" "unprognostic (9.43e-2)" "unprognostic (3.68e-2)" "unprognostic (5.74e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (1.77e-1)" "unprognostic (4.15e-3)" "unprognostic (5.54e-3)" "unprognostic (8.53e-2)" "unprognostic (2.35e-1)" "prognostic favorable (1.62e-10)" "unprognostic (1.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-2)" "unprognostic (2.54e-2)" CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166347 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.3;pituitary gland: 20.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 22.0;Excitatory neurons: 43.1;Inhibitory neurons: 192.1;Sertoli cells: 49.0;Smooth muscle cells: 22.1" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 9.9;lymphoma: 15.1;thyroid cancer: 4.0" "Breast - Adipocytes (Breast), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" CNR2 CB2 ENSG00000188822 "Cannabinoid receptor 2" P34972 1 23870515-23913362 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 8.6" "Cell type enriched" "Detected in some" 4 "B-cells: 35.2" "Cancer enriched" "Detected in single" 6 "testis cancer: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 49.2;eosinophil: 35.1;memory B-cell: 29.6;naive B-cell: 27.9;NK-cell: 19.4" "Group enriched" "Detected in many" 9 "B-cells: 29.6;granulocytes: 49.2;NK-cells: 19.4" "Group enriched" "Detected in some" 14 "Leukemia: 3.1;lymphoma: 6.3" "Lung - B-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB009719 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 22 "CAB009719: AB_2082784" "unprognostic (9.45e-4)" "unprognostic (5.40e-3)" "unprognostic (8.50e-3)" "unprognostic (8.19e-3)" "unprognostic (3.55e-3)" "unprognostic (9.34e-6)" "unprognostic (5.58e-3)" "unprognostic (6.96e-3)" "unprognostic (1.74e-1)" "unprognostic (7.87e-2)" "unprognostic (1.53e-1)" "unprognostic (4.93e-2)" "unprognostic (1.04e-3)" "unprognostic (3.67e-1)" "unprognostic (1.80e-1)" "unprognostic (3.75e-2)" "unprognostic (4.91e-2)" CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 480000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" 3 Vesicles "HPA007225: AB_1848869, HPA007226: AB_2667782" "unprognostic (1.55e-2)" "unprognostic (9.75e-2)" "unprognostic (3.33e-2)" "unprognostic (9.76e-2)" "unprognostic (2.78e-1)" "unprognostic (4.28e-2)" "unprognostic (3.72e-2)" "unprognostic (7.28e-3)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-3)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" "unprognostic (8.77e-3)" "unprognostic (2.26e-1)" CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 41.1" "Group enriched" "Detected in many" 8 "Early spermatids: 74.4;Late spermatids: 125.4;Spermatocytes: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 107.9;skeletal muscle: 125.1" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Muller glia cells: 77.2;Paneth cells: 36.9;Sertoli cells: 24.5" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "Neuroblastoma: 93.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" 2 "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" CNTN6 NB-3 ENSG00000134115 "Contactin 6" Q9UQ52 3 1092658-1404217 "Predicted membrane proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;thyroid gland: 9.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 123.4;Inhibitory neurons: 72.6;Oligodendrocyte precursor cells: 49.5" "Group enriched" "Detected in some" 15 "renal cancer: 2.7;thyroid cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 1.5;thyroid cancer: 1.9" "Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016645 Uncertain NA NA 4700000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA016645: AB_1847149" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.27e-1)" "unprognostic (3.99e-1)" "unprognostic (3.16e-1)" "unprognostic (1.05e-4)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (3.80e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.26e-3)" "unprognostic (5.45e-2)" "unprognostic (5.23e-2)" "unprognostic (1.15e-1)" "unprognostic (4.46e-2)" CNTNAP1 "Caspr, CNTNAP, NRXN4, p190" ENSG00000108797 "Contactin associated protein 1" P78357 17 42682531-42699993 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8;Endometrial stromal cells: 17.5;Excitatory neurons: 44.0;Horizontal cells: 27.1;Inhibitory neurons: 36.1" "Cancer enhanced" "Detected in all" "glioma: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011772 Approved Approved Nucleoplasm NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" Nucleoplasm "HPA011772: AB_1079541" "unprognostic (4.04e-2)" "unprognostic (3.69e-1)" "unprognostic (2.37e-3)" "unprognostic (1.89e-1)" "unprognostic (5.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.59e-1)" "unprognostic (9.76e-3)" "unprognostic (1.99e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.16e-14)" "unprognostic (9.52e-3)" "unprognostic (2.27e-2)" "unprognostic (3.11e-2)" "unprognostic (7.37e-3)" CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 36.0;retina: 14.0" "Group enriched" "Detected in many" 5 "Excitatory neurons: 3268.5;Inhibitory neurons: 6568.1" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.8" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 4 "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39064710-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 99.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "neutrophil: 7.4" "Lineage enriched" "Detected in single" 75 "granulocytes: 7.4" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" HPA047731 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA047731: AB_2680137" "unprognostic (9.06e-3)" "unprognostic (3.07e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-3)" "unprognostic (1.93e-3)" CNTNAP3B ENSG00000154529 "Contactin associated protein family member 3B" Q96NU0 9 41890314-42129510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Endothelial cells: 37.4;Excitatory neurons: 33.4;Inhibitory neurons: 156.1;Lymphatic endothelial cells: 59.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 3.5" "Low cancer specificity" "Detected in many" HPA047731 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA047731: AB_2680137" "unprognostic (2.68e-2)" "unprognostic (9.63e-3)" "unprognostic (2.20e-2)" "unprognostic (2.87e-1)" "unprognostic (1.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.20e-3)" "unprognostic (5.70e-2)" "unprognostic (2.27e-1)" "unprognostic (7.20e-2)" "unprognostic (3.74e-3)" "unprognostic (1.64e-1)" "unprognostic (7.74e-2)" "unprognostic (5.78e-3)" "unprognostic (7.93e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-4)" CNTNAP4 "CASPR4, KIAA1763" ENSG00000152910 "Contactin associated protein family member 4" Q9C0A0 16 76277278-76560757 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 95.6" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 311.5;Oligodendrocytes: 1070.6" "Cancer enriched" "Detected in single" 5 "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.6;Neuroblastoma: 2.5;Rhabdoid: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031859 Enhanced NA NA 2800000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" "HPA031859: AB_10601360" "unprognostic (7.88e-2)" "unprognostic (7.19e-2)" "unprognostic (6.58e-2)" "unprognostic (2.46e-1)" "unprognostic (1.55e-2)" "unprognostic (1.50e-3)" "unprognostic (9.42e-3)" "unprognostic (1.91e-2)" "unprognostic (5.26e-4)" "unprognostic (1.83e-2)" "unprognostic (2.00e-2)" "unprognostic (4.56e-1)" "unprognostic (1.09e-1)" CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124921219 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.9;retina: 2.8" "Group enriched" "Detected in some" 53 "Excitatory neurons: 534.8;Inhibitory neurons: 867.8;Oligodendrocyte precursor cells: 713.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.5" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: AB_2686083, HPA069356: AB_2686127" "unprognostic (6.32e-3)" "unprognostic (6.38e-2)" "unprognostic (1.23e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-6)" "unprognostic (3.65e-3)" "unprognostic (5.32e-2)" "unprognostic (9.58e-2)" COA1 "C7orf44, FLJ10803, MITRAC15" ENSG00000106603 "Cytochrome c oxidase assembly factor 1" Q9GZY4 7 43608456-43729717 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011944 Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA011944: AB_1848671" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.21e-1)" "unprognostic (4.42e-2)" "unprognostic (2.22e-2)" "unprognostic (5.22e-2)" "unprognostic (6.74e-2)" "unprognostic (1.52e-1)" "unprognostic (3.52e-1)" "unprognostic (1.02e-2)" "unprognostic (2.56e-2)" "unprognostic (5.39e-2)" COA3 "CCDC56, COX25, hCOA3, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 562.4;Proximal tubular cells: 679.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 5 Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.1;epididymis: 19.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 37.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 23.6" "Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050392 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 30: Granulocytes - Unknown function" "HPA050392: AB_2681110" "unprognostic (2.79e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (4.67e-4)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "unprognostic (7.43e-2)" "unprognostic (6.16e-3)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (2.53e-2)" "unprognostic (1.36e-5)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-2)" "unprognostic (3.93e-2)" COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 564.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 670.0;Basal respiratory cells: 124.0;Basal squamous epithelial cells: 189.5;Breast myoepithelial cells: 95.4;Distal enterocytes: 135.2;Salivary duct cells: 114.7;Suprabasal keratinocytes: 155.0" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 200.6;head and neck cancer: 440.5" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in all" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 32000 "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.3;testis: 15.8" "Cell type enhanced" "Detected in many" "Early spermatids: 105.8;Inhibitory neurons: 262.8;Late spermatids: 53.0;Rod photoreceptor cells: 92.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 29: Forebrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 30.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 141.6;Hofbauer cells: 130.7;Lymphatic endothelial cells: 177.2;Microglial cells: 234.4;Syncytiotrophoblasts: 96.4" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.1;Rhabdoid: 14.8" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" 2 "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 36.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.8" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 3: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 61: Plasma cells - Immunoglobulins & histones" 5 "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 55.0" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 70.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.1" "Heart muscle - Cardiomyocytes" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in many" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme Yes No "Cluster 30: Heart muscle - Heart development" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" COX10 ENSG00000006695 "Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10" Q12887 17 14069490-14231736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Heme biosynthesis, Lipid metabolism" Transferase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.9;tongue: 42.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 131.3;Late spermatids: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032005, HPA032006" Supported Supported Nucleoli,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "Nucleoli, Cytosol" "HPA032005: AB_10603560, HPA032006: AB_10670554" "unprognostic (6.17e-2)" "unprognostic (3.14e-1)" "unprognostic (1.41e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.40e-2)" "unprognostic (6.27e-3)" "unprognostic (1.07e-1)" "unprognostic (9.46e-3)" "unprognostic (6.46e-2)" "prognostic favorable (4.32e-6)" "prognostic favorable (8.73e-4)" "unprognostic (8.82e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" COX11 COX11P ENSG00000166260 "Cytochrome c oxidase copper chaperone COX11" Q9Y6N1 17 54951902-54968703 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044020 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA044020: AB_2678777" "unprognostic (1.42e-1)" "unprognostic (6.59e-2)" "prognostic favorable (4.30e-4)" "unprognostic (3.13e-1)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (4.69e-2)" "unprognostic (2.85e-2)" "unprognostic (4.11e-2)" "unprognostic (8.12e-3)" "unprognostic (8.18e-2)" "unprognostic (3.65e-2)" "unprognostic (2.02e-3)" "unprognostic (2.69e-2)" "unprognostic (9.25e-2)" "unprognostic (6.29e-2)" "unprognostic (7.85e-2)" COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 613.7;Distal tubular cells: 580.9;Proximal tubular cells: 857.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 2 Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" COX15 CEMCOX2 ENSG00000014919 "Cytochrome c oxidase assembly homolog COX15" Q7KZN9 10 99710868-99732127 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037727, HPA037728, HPA066096" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria Nucleoplasm "HPA037727: AB_10672391, HPA037728: AB_10672463, HPA066096: AB_2685616" "unprognostic (9.74e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (6.55e-3)" "unprognostic (1.50e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.96e-1)" "unprognostic (6.84e-2)" "unprognostic (1.76e-1)" "unprognostic (3.40e-2)" "unprognostic (8.34e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-2)" "unprognostic (3.40e-2)" COX18 "FLJ38991, OXA1L2" ENSG00000163626 "Cytochrome c oxidase assembly factor COX18" Q8N8Q8 4 73052362-73069755 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046772, HPA049489" Approved NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 77: Plasma cells - Protein processing" "HPA046772: AB_2679799, HPA049489: AB_2680791" "unprognostic (3.32e-3)" "unprognostic (2.01e-1)" "prognostic favorable (6.31e-4)" "unprognostic (9.01e-3)" "unprognostic (2.43e-1)" "unprognostic (2.17e-1)" "unprognostic (3.81e-2)" "unprognostic (6.97e-2)" "unprognostic (2.92e-1)" "unprognostic (5.29e-3)" "unprognostic (1.58e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.22e-7)" "unprognostic (1.28e-2)" "unprognostic (2.94e-1)" "unprognostic (5.80e-2)" "unprognostic (1.22e-3)" COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 485.5;Distal tubular cells: 491.7;Proximal tubular cells: 517.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 23: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 19 Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" COX4I1 "COX4, COX4-1, COXIV, COXIV-1" ENSG00000131143 "Cytochrome c oxidase subunit 4I1" P13073 16 85798633-85807068 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4780.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002485, CAB004080" Supported Supported Mitochondria NA NA 55000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "CAB004080: AB_2085427, HPA002485: AB_1078559" "unprognostic (4.73e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-1)" "unprognostic (6.18e-3)" "unprognostic (2.47e-1)" "unprognostic (4.52e-2)" "unprognostic (2.65e-1)" "unprognostic (1.46e-1)" "unprognostic (5.97e-2)" "unprognostic (7.82e-3)" "unprognostic (3.32e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.56e-8)" "unprognostic (4.23e-2)" "unprognostic (4.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.38e-2)" COX6A1 "COX6A, COX6AL" ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1660.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2004.4;Proximal enterocytes: 1967.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062394 Approved Supported Mitochondria NA NA 85000 "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 Mitochondria "HPA062394: AB_2684749" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (5.10e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-1)" "unprognostic (8.78e-2)" "unprognostic (3.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (3.22e-2)" "unprognostic (2.82e-1)" "prognostic favorable (6.50e-7)" "unprognostic (2.53e-1)" "unprognostic (1.31e-1)" "unprognostic (5.48e-2)" "unprognostic (2.63e-2)" COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2774.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 636.0" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Enhanced Mitochondria NA NA 210000 "Cluster 6: T-cells - T-cell receptor" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 4 Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" COX7A2L "COX7AR, COX7RP, EB1, SCAF1, SCAFI, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 25: Non-specific - Ribosome" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB073545: , HPA059124: AB_2683912" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (5.45e-2)" "unprognostic (4.60e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.07e-3)" "unprognostic (1.54e-2)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" COX7B ENSG00000131174 "Cytochrome c oxidase subunit 7B" P24311 X 77899440-77907376 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1084.1;tongue: 728.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3334.9;Distal tubular cells: 2246.7;Proximal tubular cells: 1944.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA058041 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA058041: AB_2683587" "unprognostic (1.24e-2)" "unprognostic (1.76e-3)" "unprognostic (8.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.26e-1)" "unprognostic (8.10e-2)" "prognostic favorable (6.80e-6)" "unprognostic (8.58e-2)" "unprognostic (4.62e-1)" "unprognostic (6.38e-2)" "prognostic favorable (2.43e-4)" COX7C ENSG00000127184 "Cytochrome c oxidase subunit 7C" P15954 5 86617928-86620962 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2300.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4848.6;Distal tubular cells: 5452.3;Proximal tubular cells: 6025.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046647 Approved NA NA 39000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 3 "HPA046647: AB_2679736" "unprognostic (1.45e-1)" "unprognostic (1.74e-2)" "unprognostic (9.10e-2)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (1.04e-1)" "unprognostic (3.70e-1)" "unprognostic (4.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.23e-5)" "unprognostic (4.56e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (4.46e-2)" COX8A "COX, COX8, COX8-2, COX8L, VIII, VIII-L" ENSG00000176340 "Cytochrome c oxidase subunit 8A" P10176 11 63974620-63976543 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1873.2;Distal tubular cells: 2320.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055942 Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 4 "HPA055942: AB_2682979" "unprognostic (6.93e-2)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.02e-2)" "unprognostic (2.24e-1)" "unprognostic (7.70e-3)" "unprognostic (2.01e-2)" "unprognostic (2.12e-1)" "unprognostic (3.46e-1)" "unprognostic (6.49e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic favorable (2.51e-6)" "unprognostic (2.70e-2)" "unprognostic (5.41e-2)" "unprognostic (1.13e-1)" "unprognostic (8.44e-2)" COX8C COX8-3 ENSG00000187581 "Cytochrome c oxidase subunit 8C" Q7Z4L0 14 93347182-93348356 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 184 "testis: 74.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1859.6" "Group enriched" "Detected in some" 8 "ovarian cancer: 2.9;testis cancer: 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003127 Approved NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 11: Late spermatids - Unknown function" "HPA003127: AB_1078560" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (3.76e-3)" "unprognostic (2.11e-1)" "unprognostic (2.77e-2)" "unprognostic (7.71e-2)" "unprognostic (3.83e-1)" "unprognostic (1.99e-2)" "unprognostic (8.28e-2)" "unprognostic (6.33e-2)" "unprognostic (2.64e-2)" "unprognostic (9.15e-2)" CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378927-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 181.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052796 Approved Approved Cytosol NA NA 1700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" Cytosol "HPA052796: AB_2681953" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" CPLANE1 "C5orf42, FLJ13231, Hug, JBTS17" ENSG00000197603 "Ciliogenesis and planar polarity effector complex subunit 1" Q9H799 5 37106228-37249376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 168.3;Inhibitory neurons: 159.6;Oligodendrocyte precursor cells: 119.8;Oligodendrocytes: 117.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036775, HPA036776" Approved Approved Cytosol NA NA "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "HPA036775: AB_10669914, HPA036776: AB_2675308" "unprognostic (3.06e-1)" "unprognostic (2.00e-1)" "unprognostic (4.96e-2)" "unprognostic (4.13e-3)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-3)" "unprognostic (5.88e-2)" "unprognostic (3.13e-2)" "unprognostic (6.20e-3)" "unprognostic (3.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-1)" CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 150.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.9;Glandular and luminal cells: 227.4;granulocytes: 410.2;Kupffer cells: 277.8;Sertoli cells: 315.5;Syncytiotrophoblasts: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.1;intermediate monocyte: 14.5;myeloid DC: 16.7;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 5 "dendritic cells: 16.7;monocytes: 21.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" CPOX "CPO, CPX, HCP" ENSG00000080819 "Coproporphyrinogen oxidase" P36551 3 98579446-98593648 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Erythroid cells: 236.2;Extravillous trophoblasts: 79.5;Oligodendrocytes: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015736, HPA054448" Supported Mitochondria No No 170000 "Cluster 14: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" Mitochondria "HPA015736: AB_1847194, HPA054448: AB_2682490" "unprognostic (2.14e-1)" "unprognostic (1.04e-1)" "unprognostic (4.07e-2)" "unprognostic (6.09e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-2)" "unprognostic (8.58e-3)" "unprognostic (7.14e-2)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.62e-1)" "unprognostic (2.67e-2)" "unprognostic (2.15e-2)" "unprognostic (2.57e-1)" CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria NA NA 45000 "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" Mitochondria "HPA008835: AB_1078563" "prognostic unfavorable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favorable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 234.9;skeletal muscle: 139.5;testis: 78.5;tongue: 219.1" "Group enriched" "Detected in some" 4 "Early spermatids: 32.6;Late spermatids: 80.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA079265 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Late spermatids - Unknown function" 2 "HPA079265: " "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (6.71e-3)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (8.89e-2)" "unprognostic (7.16e-2)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-3)" "unprognostic (9.76e-3)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" "unprognostic (1.14e-1)" "unprognostic (8.43e-2)" "unprognostic (3.15e-5)" CPT1C "CATL1, CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.8;choroid plexus: 28.5;pituitary gland: 27.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 35.3;Excitatory neurons: 32.8;Horizontal cells: 27.1;Inhibitory neurons: 26.9;Late spermatids: 30.4;Oligodendrocyte precursor cells: 19.8" "Cancer enriched" "Detected in many" 5 "glioma: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.9;Rhabdoid: 50.9" "Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014529, HPA063621" Approved Approved Centrosome NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" Centrosome "HPA014529: AB_1847206, HPA063621: AB_2732706" "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.84e-4)" "unprognostic (4.36e-1)" "unprognostic (1.92e-10)" "unprognostic (9.44e-4)" "unprognostic (3.35e-2)" "unprognostic (3.91e-1)" "unprognostic (4.72e-3)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.8;lymphoid tissue: 26.5" "Cell type enhanced" "Detected in some" "B-cells: 40.6;Erythroid cells: 17.0;Hofbauer cells: 16.9;Kupffer cells: 96.2;Macrophages: 42.4;monocytes: 23.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 53.8;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.8" "Group enriched" "Detected in some" 9 "Leukemia: 3.6;lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophil_2, Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 20: Non-specific - DNA binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" CR2 "C3DR, CD21" ENSG00000117322 "Complement C3d receptor 2" P20023 1 207453024-207489895 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 171.2" "Cell type enhanced" "Detected in some" "B-cells: 43.3;Oocytes: 20.6;Plasma cells: 9.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.1;stomach cancer: 5.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory B-cell: 17.6;naive B-cell: 20.5" "Lineage enriched" "Detected in many" 8 "B-cells: 20.5" "Group enriched" "Detected in some" 7 "Leukemia: 8.6;lymphoma: 17.5;Myeloma: 8.1" "Not detected" "Not detected" "CAB002659, HPA052942, HPA060715" Enhanced NA NA 220000000 "Cluster 18: Non-specific - Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 "CAB002659: , HPA052942: AB_2681994, HPA060715: AB_2684349" "prognostic favorable (6.90e-4)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (1.27e-3)" "unprognostic (1.18e-1)" "unprognostic (6.62e-3)" "unprognostic (1.91e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (7.95e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-1)" "unprognostic (2.19e-1)" "unprognostic (2.09e-2)" "unprognostic (3.35e-2)" CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 72.4" "Cell type enhanced" "Detected in some" "Astrocytes: 445.3;Cone photoreceptor cells: 117.2;Inhibitory neurons: 124.5;Oligodendrocyte precursor cells: 262.7;Oligodendrocytes: 98.3;Rod photoreceptor cells: 149.5" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.8" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.8" "Group enriched" "Detected in some" 5 "cervical cancer: 4.7;Sarcoma: 4.6" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 4 Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;kidney: 5.6;retina: 7.8" "Cell type enhanced" "Detected in many" "Astrocytes: 38.4;Bipolar cells: 36.8;Cone photoreceptor cells: 62.9;Mesothelial cells: 27.4;Oligodendrocytes: 25.0;Rod photoreceptor cells: 106.8" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.8" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043674 Approved Supported "Intracellular and membrane" "Developmental protein" NA NA 210000 "Cluster 17: Neuronal - Synaptic function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 167.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 14.1" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 21 "B-cells: 3.1;T-cells: 9.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" CREB3 "Luman, LZIP, sLZIP" ENSG00000107175 "CAMP responsive element binding protein 3" O43889 9 35732598-35736999 "Predicted membrane proteins, Transcription factors" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 427.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030978 Supported Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 25 Cytosol "HPA030978: AB_2673683" "unprognostic (1.73e-3)" "unprognostic (9.72e-2)" "unprognostic (9.32e-2)" "unprognostic (5.62e-3)" "unprognostic (3.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (4.29e-2)" "unprognostic (4.63e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.13e-1)" "unprognostic (1.65e-1)" "prognostic favorable (3.77e-5)" "unprognostic (1.48e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 129.7;salivary gland: 80.6" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 90.2;Glandular and luminal cells: 107.3;Intestinal goblet cells: 289.7" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024069, CAB026151, HPA062116" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 163 Nucleoplasm Cytosol "CAB026151: , HPA024069: AB_1854750, HPA062116: " "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 222.1;Plasma cells: 223.9;Syncytiotrophoblasts: 164.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" CREB3L3 "CREB-H, CREBH" ENSG00000060566 "CAMP responsive element binding protein 3 like 3" Q68CJ9 19 4153631-4173054 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 71 "intestine: 250.0;liver: 405.1" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 377.7" "Cancer enriched" "Detected in many" 18 "liver cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 8.0;liver cancer: 21.5;pancreatic cancer: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040671, HPA056228" Enhanced NA NA 32000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 18 "HPA040671: AB_2677072, HPA056228: AB_2683072" "unprognostic (1.86e-2)" "unprognostic (2.13e-1)" "unprognostic (2.81e-1)" "unprognostic (1.66e-2)" "unprognostic (8.41e-4)" "unprognostic (1.79e-4)" "unprognostic (1.88e-1)" "unprognostic (5.28e-4)" "unprognostic (3.01e-1)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.53e-6)" "unprognostic (3.18e-3)" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (3.35e-2)" CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 102.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 53.4;Intestinal goblet cells: 65.4;Prostatic glandular cells: 141.7" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 111.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 32: Basophils - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933793-9945413 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.2;Excitatory neurons: 36.8;Inhibitory neurons: 35.5;Oligodendrocytes: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 19000000 "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 49: Non-specific - Transcription" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784277-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 19.5;pituitary gland: 19.8" "Cell type enriched" "Detected in single" 10 "Bipolar cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025251 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" 1 "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 21.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 8.0;Horizontal cells: 11.3;Inhibitory neurons: 4.7" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 48.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 5.5" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 158.3" "Cell type enhanced" "Detected in many" "Adipocytes: 241.5;Smooth muscle cells: 170.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Group enriched" "Detected in some" 5 "granulocytes: 31.5;Langerhans cells: 9.3" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Group enriched" "Detected in some" 4 "Adrenocortical cancer: 7.0;Leukemia: 7.4;lymphoma: 2.4;Myeloma: 5.2" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Mast cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA075272 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Leukemia - Signal transduction" "Cluster 14: Langerhans cells - Innate immune response" "Plasma membrane" "HPA075272: " "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10335.0;skeletal muscle: 6727.5;tongue: 9029.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7159.1;Proximal tubular cells: 7075.7;Schwann cells: 1861.7;Skeletal myocytes: 4337.4" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 236.2;ovarian cancer: 273.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA 370000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 18 "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 530.6;tongue: 577.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 281.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 59.0;granulocytes: 199.8;Secretory cells: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" Cytokine NA NA 270000 22000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.4;placenta: 99.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 115.8;Hofbauer cells: 327.3;Kupffer cells: 256.3;Langerhans cells: 98.3;Macrophages: 218.3;Microglial cells: 128.8;monocytes: 218.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.5;non-classical monocyte: 650.1" "Lineage enriched" "Detected in many" 5 "monocytes: 650.1" "Cancer enhanced" "Detected in many" "Leukemia: 13.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 1600000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 243.7;Extravillous trophoblasts: 130.8;Langerhans cells: 703.6;Macrophages: 108.0;Schwann cells: 140.4;Syncytiotrophoblasts: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 319.8" "Group enriched" "Detected in all" 29 "dendritic cells: 170.1;granulocytes: 319.8;monocytes: 160.9" "Cancer enriched" "Detected in many" 7 "Adrenocortical cancer: 111.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" Receptor NA NA 13000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 1 "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" CSF2RB "betaGMR, CD131, IL3RB, IL5RB" ENSG00000100368 "Colony stimulating factor 2 receptor subunit beta" P32927 22 36913628-36940439 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 63.7" "Cell type enhanced" "Detected in many" "dendritic cells: 115.7;Extravillous trophoblasts: 43.3;granulocytes: 68.5;Kupffer cells: 36.9;Langerhans cells: 74.0;Late spermatids: 40.9;Macrophages: 36.3;monocytes: 36.6;Plasma cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 239.1;neutrophil: 76.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 239.1" "Group enriched" "Detected in some" 47 "Leukemia: 43.7;lymphoma: 16.5;Myeloma: 15.2" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA078677 Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 6 "Golgi apparatus" "HPA078677: AB_2732389" "unprognostic (1.67e-2)" "unprognostic (9.44e-3)" "unprognostic (1.03e-2)" "unprognostic (6.66e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.47e-5)" "unprognostic (1.86e-1)" "unprognostic (1.94e-2)" "unprognostic (4.38e-1)" "unprognostic (9.57e-2)" "unprognostic (1.33e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-3)" "unprognostic (5.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.95e-1)" "unprognostic (8.52e-2)" CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.3;lung: 132.6;lymphoid tissue: 366.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 395.7;Syncytiotrophoblasts: 1355.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1924.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 1924.2" "Cancer enriched" "Detected in some" 25 "Leukemia: 32.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" Receptor NA NA 150000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.5;retina: 1.5;testis: 2.5" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4701.7;Inhibitory neurons: 3746.3;Oligodendrocyte precursor cells: 4243.1" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Neurons - Neuronal signaling" 1 Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 884.8;Inhibitory neurons: 829.3;Oligodendrocyte precursor cells: 1652.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "HPA029007: AB_10601802, HPA029008: " "unprognostic (2.26e-1)" "unprognostic (2.16e-2)" "unprognostic (2.83e-2)" "unprognostic (5.97e-2)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (3.54e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-2)" "unprognostic (5.03e-10)" "unprognostic (1.95e-1)" "unprognostic (4.14e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-3)" CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 35: Respiratory epithelial cells - Unknown function" 16 "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165525-64356173 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 92.2;Late spermatids: 246.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 25: Bipolar cells - Visual perception" 2 Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.5" "Group enriched" "Detected in some" 4 "Melanocytes: 17.2;Oligodendrocyte precursor cells: 53.8;Schwann cells: 16.0;Sertoli cells: 54.4;Skeletal myocytes: 14.6;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 73.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Endothelial cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Approved "Plasma membrane" NA NA 48000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" CSPG5 NGC ENSG00000114646 "Chondroitin sulfate proteoglycan 5" O95196 3 47562238-47580792 "Predicted membrane proteins" "Differentiation, Growth regulation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 103.4;choroid plexus: 54.9;retina: 27.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.5;Astrocytes: 64.1;Muller glia cells: 81.8;Oligodendrocyte precursor cells: 219.3" "Cancer enriched" "Detected in many" 19 "glioma: 48.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 14.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049529, HPA067818, HPA071779" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" Nucleoplasm Mitochondria "HPA049529: AB_2680805, HPA067818: AB_2685905, HPA071779: AB_2686446" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (8.87e-2)" "unprognostic (3.12e-2)" "unprognostic (2.88e-1)" "unprognostic (7.66e-2)" "unprognostic (5.05e-4)" "unprognostic (1.40e-1)" "unprognostic (3.82e-1)" "prognostic favorable (2.14e-4)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (3.41e-4)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" CTAGE1 "CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2" ENSG00000212710 "Cutaneous T cell lymphoma-associated antigen 1" "Q96RT6, Q9HC47" 18 22413599-22417915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 10.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 162.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922, CAB016204" Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "CAB016204: AB_673617, HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (1.41e-1)" "unprognostic (5.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.52e-1)" "unprognostic (1.70e-2)" "unprognostic (3.15e-1)" "unprognostic (1.63e-1)" "unprognostic (3.62e-1)" CTAGE15 CTAGE15P ENSG00000271079 "CTAGE family member 15" A4D2H0 7 143571801-143574387 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (2.82e-1)" "unprognostic (8.64e-2)" "unprognostic (3.23e-1)" "unprognostic (3.32e-1)" "unprognostic (2.44e-1)" "unprognostic (2.23e-1)" "unprognostic (4.52e-2)" "unprognostic (9.94e-2)" "unprognostic (3.38e-1)" "unprognostic (7.95e-2)" "unprognostic (3.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.33e-1)" "unprognostic (2.91e-2)" "unprognostic (2.39e-1)" CTAGE4 "cTAGE-4, FLJ43692" ENSG00000288784 "CTAGE family member 4" Q8IX94 7 144183466-144186080 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 10.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA000387, HPA000922" Uncertain NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "HPA000387: AB_1078582, HPA000922: AB_1078581" CTAGE6 "CTAGE6P, MGC41943" ENSG00000271321 "CTAGE family member 6" Q86UF2 7 143755089-143757696 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 62 "testis: 14.0" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Spermatocytes: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (1.51e-2)" "unprognostic (8.90e-12)" "unprognostic (1.73e-2)" "unprognostic (2.86e-1)" CTAGE8 ENSG00000289604 "CTAGE family member 8" P0CG41 7 144266674-144269288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 6.6;thyroid gland: 5.0" "Region enriched" "Detected in single" 4 "choroid plexus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA000387, HPA000922" Uncertain NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "HPA000387: AB_1078582, HPA000922: AB_1078581" CTAGE9 ENSG00000236761 "CTAGE family member 9" A4FU28 6 131708441-131711017 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 8.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.0;Early spermatids: 21.0;Intestinal goblet cells: 3.5;Paneth cells: 4.7;Spermatocytes: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (3.92e-2)" "unprognostic (6.84e-2)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (9.89e-3)" "unprognostic (2.36e-1)" "unprognostic (5.55e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-2)" "unprognostic (5.74e-4)" "unprognostic (3.15e-2)" "unprognostic (9.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.41e-1)" CTCFL "BORIS, CT27, dJ579F20.2" ENSG00000124092 "CCCTC-binding factor like" Q8NI51 20 57495966-57525652 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 10.8" "Group enriched" "Detected in some" 10 "Spermatocytes: 73.6;Spermatogonia: 125.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 19.0;cervical cancer: 18.4" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA001472 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA001472: AB_1078583" "unprognostic (2.50e-1)" "unprognostic (4.01e-2)" "unprognostic (7.70e-2)" "unprognostic (1.85e-5)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-2)" "unprognostic (5.26e-3)" "unprognostic (3.60e-1)" "unprognostic (2.20e-1)" "unprognostic (9.00e-2)" "unprognostic (4.16e-2)" "unprognostic (4.75e-4)" "unprognostic (2.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.84e-2)" CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 395.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 33: Non-specific - DNA binding" 2 "Lipid droplets" "HPA037439: AB_10601264, HPA066466: AB_2732745" "unprognostic (7.11e-2)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "prognostic favorable (6.45e-4)" "unprognostic (3.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.61e-2)" "unprognostic (1.50e-2)" "unprognostic (2.98e-1)" "unprognostic (9.90e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.37e-1)" "unprognostic (2.77e-3)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "unprognostic (2.02e-2)" CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 30.9;Late spermatids: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 28.2;monocytes: 10.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074687 Supported Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 46: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA074687: " "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 879.8;Club cells: 507.1;Hofbauer cells: 1008.0;Ionocytes: 520.6;Macrophages: 465.3;monocytes: 724.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme No No 19000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 407.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 319.3;Langerhans cells: 84.8;Leydig cells: 121.2;Peritubular cells: 148.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 16 "choroid plexus: 31.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Lineage enriched" "Detected in single" 5 "monocytes: 1.9" "Cancer enriched" "Detected in many" 5 "skin cancer: 65.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" CTXN1 FLJ25968 ENSG00000178531 "Cortexin 1" P60606 19 7924491-7926135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "brain: 673.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 139.7;Mesothelial cells: 40.3;Secretory cells: 51.1;Sertoli cells: 29.9" "Group enriched" "Detected in all" 4 "endometrial cancer: 69.5;glioma: 56.3;ovarian cancer: 138.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016669 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA016669: AB_1847330" "unprognostic (1.49e-2)" "unprognostic (3.52e-2)" "unprognostic (1.79e-2)" "unprognostic (2.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (5.42e-2)" "unprognostic (2.17e-1)" "unprognostic (2.58e-1)" "unprognostic (2.28e-2)" "unprognostic (1.69e-3)" "unprognostic (3.31e-2)" "unprognostic (1.56e-3)" "unprognostic (4.84e-2)" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "unprognostic (9.41e-2)" CTXN2 ENSG00000233932 "Cortexin 2" P0C2S0 15 48178122-48203758 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.0;pituitary gland: 1.0;retina: 1.1" "Group enriched" "Detected in some" 5 "Early spermatids: 48.3;Late spermatids: 34.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053168 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA053168: AB_2682066" "unprognostic (1.90e-1)" "unprognostic (3.85e-3)" "unprognostic (7.43e-2)" "unprognostic (2.18e-4)" "unprognostic (6.81e-3)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" "unprognostic (4.61e-2)" CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 361.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 30: Heart muscle - Heart development" "Cluster 2: Neurons - Nucleosome" "Cluster 39: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" CUZD1 "ERG-1, UO-44" ENSG00000138161 "CUB and zona pellucida like domains 1" Q86UP6 10 122832158-122846175 "Predicted membrane proteins" "Cell adhesion, Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1623 "pancreas: 2338.0" "Cell type enriched" "Detected in some" 42 "Exocrine glandular cells: 71.9" "Cancer enriched" "Detected in some" 54 "pancreatic cancer: 32.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068479, HPA068660, HPA074117" Enhanced NA No "Cluster 15: Pancreas - Proteolysis" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "HPA068479: AB_2685995, HPA068660: AB_2686015, HPA074117: AB_2686663" "unprognostic (4.68e-2)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "unprognostic (1.52e-5)" "unprognostic (8.08e-2)" "unprognostic (5.20e-3)" "unprognostic (1.16e-4)" "unprognostic (4.19e-2)" "unprognostic (3.03e-2)" "unprognostic (5.15e-2)" "unprognostic (8.46e-2)" "unprognostic (6.64e-3)" "unprognostic (2.75e-3)" "unprognostic (4.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.56e-1)" "unprognostic (4.83e-4)" CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated cyclophilin" Q6UX04 5 64766368-65102412 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: AB_2685561" "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;prostate: 41.4;skin 1: 24.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.5;Ciliated cells: 34.1;Distal enterocytes: 25.3;Glandular and luminal cells: 20.5;Prostatic glandular cells: 80.5;Suprabasal keratinocytes: 65.9" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "prostate cancer: 16.8" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 112.5;Basal respiratory cells: 55.0;Breast glandular cells: 62.9;Club cells: 53.3;Endothelial cells: 54.3;Ionocytes: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026192, HPA040361, CAB080311" Approved Supported "Plasma membrane" "Secreted to blood" Chemokine NA NA 1870000 370000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "CAB026192: , CAB080311: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in some" "Langerhans cells: 37.8;Macrophages: 46.2;Microglial cells: 169.1;NK-cells: 184.9" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 451.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Myeloma: 16.7" "Heart muscle - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 235.9;Proximal enterocytes: 218.0;Suprabasal keratinocytes: 220.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted - unknown location" Receptor NA NA 18000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 4051.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.2;intermediate monocyte: 107.3;myeloid DC: 38.2;neutrophil: 103.3;non-classical monocyte: 141.8" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.3;monocytes: 141.8" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 1100000 6800000 "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus" Vesicles "HPA053253: AB_2682091, HPA066315: AB_2685657" "unprognostic (4.64e-3)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (4.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.78e-2)" "unprognostic (4.74e-2)" "unprognostic (2.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.60e-1)" CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.7;lymphoid tissue: 39.5" "Group enriched" "Detected in some" 5 "NK-cells: 9.8;Serous glandular cells: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1477.6" "Lineage enriched" "Detected in many" 62 "granulocytes: 1477.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 3 "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.4;lymphoid tissue: 42.2" "Cell type enhanced" "Detected in some" "NK-cells: 30.8;Serous glandular cells: 19.4;Squamous epithelial cells: 13.6;Suprabasal keratinocytes: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3297.5" "Lineage enriched" "Detected in many" 109 "granulocytes: 3297.5" "Cancer enriched" "Detected in single" 9 "Leukemia: 6.9" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 11 "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;intestine: 6.2;lymphoid tissue: 15.9" "Cell type enriched" "Detected in some" 8 "dendritic cells: 379.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 307.2" "Group enriched" "Detected in many" 5 "dendritic cells: 307.2;NK-cells: 199.6;T-cells: 124.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3;lymphoma: 9.3;Myeloma: 3.7" "Adipose subcutaneous - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 3 "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" CXCR5 "BLR1, CD185, MDR15" ENSG00000160683 "C-X-C motif chemokine receptor 5" P32302 11 118883892-118897787 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "B-cell activation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;intestine: 9.9;lymphoid tissue: 30.6" "Cell type enriched" "Detected in some" 14 "B-cells: 82.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory B-cell: 67.9;naive B-cell: 92.5" "Lineage enriched" "Detected in many" 8 "B-cells: 92.5" "Cancer enriched" "Detected in some" 12 "lymphoma: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026149, HPA042432" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 "CAB026149: , HPA042432: AB_2677995" "unprognostic (8.51e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-5)" "unprognostic (2.08e-2)" "unprognostic (3.23e-3)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-5)" "unprognostic (4.21e-1)" "unprognostic (2.03e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 81.4;Prostatic glandular cells: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 49 "HPA014753: AB_1847364" "prognostic unfavorable (8.89e-5)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-5)" "unprognostic (1.81e-3)" "unprognostic (3.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.91e-2)" "unprognostic (8.97e-2)" "unprognostic (6.38e-2)" "unprognostic (8.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.89e-1)" CYB561A3 CYBASC3 ENSG00000162144 "Cytochrome b561 family member A3" Q8NBI2 11 61348754-61362283 "Enzymes, Predicted membrane proteins" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 243.6" "Group enriched" "Detected in many" 4 "dendritic cells: 285.0;Melanocytes: 536.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "memory B-cell: 315.4;naive B-cell: 387.5;plasmacytoid DC: 843.5" "Group enriched" "Detected in all" 9 "B-cells: 387.5;dendritic cells: 843.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045674, HPA052548" Approved Approved Nucleoli,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 21 Vesicles Nucleoli "HPA045674: , HPA052548: AB_2681866" "unprognostic (2.61e-1)" "unprognostic (8.78e-2)" "unprognostic (4.16e-1)" "unprognostic (3.62e-2)" "unprognostic (1.37e-1)" "unprognostic (9.41e-3)" "unprognostic (7.41e-3)" "unprognostic (2.48e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.83e-1)" "unprognostic (3.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-3)" CYB561D1 "FLJ39035, FLJ44753" ENSG00000174151 "Cytochrome b561 family member D1" Q8N8Q1 1 109494052-109502932 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027028 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 19: NK-cells - Adaptive immune response" 3 "HPA027028: AB_1847365" "unprognostic (2.15e-2)" "unprognostic (3.49e-1)" "unprognostic (1.04e-2)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "prognostic favorable (4.68e-4)" "unprognostic (4.53e-4)" "unprognostic (1.32e-1)" "unprognostic (3.45e-1)" "unprognostic (5.29e-2)" "prognostic favorable (5.16e-6)" "unprognostic (4.30e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.20e-3)" "unprognostic (2.75e-1)" "unprognostic (4.95e-3)" "unprognostic (5.82e-2)" CYB561D2 "101F6, TSP10" ENSG00000114395 "Cytochrome b561 family member D2" O14569 3 50350845-50358460 "Enzymes, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071862 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Breast glandular cells - Lactation" 16 "HPA071862: " "unprognostic (4.89e-2)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (6.98e-2)" "unprognostic (5.15e-2)" "unprognostic (2.72e-2)" "unprognostic (2.28e-3)" "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (5.41e-2)" "prognostic favorable (1.86e-4)" "unprognostic (3.26e-1)" "prognostic favorable (6.16e-5)" "unprognostic (4.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-1)" "unprognostic (7.57e-2)" CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2392.7" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2106.5;Distal tubular cells: 1512.1;Hepatocytes: 3946.9;Proximal enterocytes: 1904.2;Proximal tubular cells: 2759.2" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 34: B-cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" CYB5B CYB5-M ENSG00000103018 "Cytochrome b5 type B" O43169 16 69398402-69466264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 308.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007893 Approved Approved "Endoplasmic reticulum,Centriolar satellite,Cytosol" NA NA 99000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Cytotrophoblasts - Mitochondria" 37 "Endoplasmic reticulum" "Centriolar satellite, Cytosol" "HPA007893: AB_1847369" "unprognostic (1.13e-1)" "unprognostic (4.47e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (2.87e-3)" "unprognostic (4.35e-3)" "unprognostic (3.87e-1)" "unprognostic (1.44e-2)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "prognostic favorable (6.38e-5)" "unprognostic (9.69e-3)" "unprognostic (4.66e-2)" "unprognostic (3.78e-2)" "unprognostic (1.30e-2)" CYB5R2 ENSG00000166394 "Cytochrome b5 reductase 2" Q6BCY4 11 7665100-7677222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 135.0;testis: 129.9" "Group enriched" "Detected in many" 4 "Early spermatids: 276.6;Late spermatids: 609.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 6.1;memory B-cell: 10.6;naive B-cell: 2.8" "Group enriched" "Detected in many" 9 "B-cells: 10.6;granulocytes: 6.1" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "HPA038962, HPA061707" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Retina & Testis - Cilium" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Late spermatids - Unknown function" 6 "Golgi apparatus" Nucleoplasm "HPA038962: AB_10675954, HPA061707: AB_2732668" "unprognostic (1.47e-1)" "unprognostic (2.56e-2)" "unprognostic (8.90e-3)" "unprognostic (4.41e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-2)" "unprognostic (4.02e-2)" "unprognostic (2.48e-1)" "unprognostic (3.41e-2)" "unprognostic (1.30e-2)" "unprognostic (2.64e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.40e-1)" "unprognostic (8.16e-2)" "unprognostic (1.70e-1)" "unprognostic (7.01e-2)" CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42615730-42720870 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 25: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 50 "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643275-88651083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 813.8;lymphoid tissue: 676.6" "Cell type enhanced" "Detected in many" "dendritic cells: 1998.3;Hofbauer cells: 2720.2;Macrophages: 1684.2;monocytes: 1935.1;Plasma cells: 2344.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 756.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - T-cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009492, HPA072667" Enhanced NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 58: Macrophages - Innate immune response" 3 "CAB009492: AB_2090309, HPA072667: " "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780018-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 157.3;lymphoid tissue: 145.7" "Cell type enhanced" "Detected in many" "dendritic cells: 329.2;Hofbauer cells: 223.4;Kupffer cells: 356.9;Macrophages: 445.8;monocytes: 644.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 318.5" "Group enriched" "Detected in many" 5 "dendritic cells: 80.2;granulocytes: 106.4;monocytes: 318.5" "Group enriched" "Detected in some" 4 "Leukemia: 15.8;lymphoma: 29.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82440912-82450829 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 51 "Plasma membrane" "Cell Junctions" "HPA045696: AB_2679421" "unprognostic (1.87e-2)" "unprognostic (6.92e-3)" "unprognostic (2.25e-1)" "unprognostic (2.15e-3)" "unprognostic (5.75e-2)" "unprognostic (2.05e-3)" "unprognostic (3.81e-3)" "unprognostic (4.86e-2)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-3)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.83e-11)" "unprognostic (1.47e-1)" "unprognostic (5.51e-2)" "unprognostic (7.78e-2)" "unprognostic (9.14e-3)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.2;Leydig cells: 193.7;Peritubular cells: 215.1;Proximal enterocytes: 691.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.8;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.8" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 19 "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.7;tongue: 696.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 670.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 2 Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "placenta: 120.5" "Cell type enriched" "Detected in some" 61 "Syncytiotrophoblasts: 2667.7" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 5.3;testis cancer: 15.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.1;urinary bladder: 61.4" "Cell type enhanced" "Detected in some" "Adipocytes: 15.2;Ductal cells: 2.5;Endothelial cells: 2.7;Glandular and luminal cells: 5.5;Hepatocytes: 9.8" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 53.3;Esophageal cancer: 95.1" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 358 "liver: 495.9" "Cell type enriched" "Detected in some" 56 "Hepatocytes: 535.0" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 100.6;Fibroblasts: 139.3;Leydig cells: 155.9;Macrophages: 120.3;Peritubular cells: 168.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 157.2" "Lineage enriched" "Detected in many" 24 "monocytes: 157.2" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "midbrain: 16.4;spinal cord: 51.7" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 312.1" "Group enriched" "Detected in some" 30 "Hepatocytes: 297.2;Proximal enterocytes: 244.6" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 98.4;stomach 1: 117.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 90.2;Intestinal goblet cells: 34.6;Langerhans cells: 82.1;Proximal enterocytes: 41.7;Schwann cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 2 "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 82.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 29.2;Inhibitory neurons: 32.9;Melanocytes: 27.5;Schwann cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3492.7" "Group enriched" "Detected in some" 59 "Hepatocytes: 2573.4;Proximal enterocytes: 1348.0" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 2 Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 40.0" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Early spermatids: 6.3;Excitatory neurons: 3.8;Hepatocytes: 3.8;Inhibitory neurons: 1.8;Late spermatids: 4.6;Spermatocytes: 2.2" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 11: Late spermatids - Unknown function" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 172.8;liver: 269.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 396.8;Distal enterocytes: 264.5;Gastric mucus-secreting cells: 525.3;Hepatocytes: 410.7;Proximal enterocytes: 1064.2" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 296.4" "Group enriched" "Detected in some" 10 "Cholangiocytes: 87.8;Hepatocytes: 33.0" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Liver - Hepatocytes" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.4" "Group enriched" "Detected in some" 4 "Cholangiocytes: 3.8;Hepatocytes: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" Cytosol Vesicles "HPA072245: , HPA075539: " CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 233.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 148.6;Basal prostatic cells: 121.3;Basal respiratory cells: 107.2;Ciliated cells: 433.5;Club cells: 368.1;Ionocytes: 260.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bladder cancer: 12.1;breast cancer: 28.8" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;liver: 39.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.5;Gastric mucus-secreting cells: 57.8;Paneth cells: 45.3;Proximal enterocytes: 113.7;Suprabasal keratinocytes: 40.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.2;eosinophil: 14.9" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.0;Gastric cancer: 5.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Urothelial cells, Thyroid - Fibroblasts" HPA058960 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 78.0;kidney: 39.4;liver: 161.6" "Group enriched" "Detected in some" 9 "Hepatocytes: 113.5;Proximal enterocytes: 202.2" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 81 "granulocytes: 8.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8;Gastric cancer: 1.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 33 "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 56.8;vagina: 22.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 53.8;Breast glandular cells: 8.5;monocytes: 8.9;Prostatic glandular cells: 11.1;Suprabasal keratinocytes: 31.2" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 8 "monocytes: 14.2;T-cells: 4.3" "Cancer enriched" "Detected in some" 31 "Bone cancer: 42.8" "Lung - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 4 "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "seminal vesicle: 208.2" "Cell type enriched" "Detected in some" 43 "Basal prostatic cells: 1208.1" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "prostate cancer: 13.7" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 60: Prostate cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Muller glia cells - Visual perception" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.8;salivary gland: 30.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 36.5;Ciliated cells: 30.3;Club cells: 55.4;Excitatory neurons: 36.2;Inhibitory neurons: 28.0;Ionocytes: 39.8;Salivary duct cells: 43.0" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.2;prostate cancer: 11.6" "Liver - Hepatocytes, Stomach - Chief cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92084987-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 52.6;Kupffer cells: 56.0;Oligodendrocytes: 49.4;Squamous epithelial cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA041325: AB_2677411, HPA043508: AB_2678520" "unprognostic (6.68e-2)" "prognostic unfavorable (6.12e-4)" "unprognostic (3.48e-2)" "unprognostic (1.18e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.84e-2)" "unprognostic (1.36e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-9)" "unprognostic (1.82e-1)" "unprognostic (2.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.09e-3)" CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 88.9;Oligodendrocyte precursor cells: 88.7;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Cancer enhanced" "Detected in some" "skin cancer: 2.7" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271468-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in many" "Adipocytes: 27.2;B-cells: 61.7;dendritic cells: 68.2;granulocytes: 42.7;Hofbauer cells: 35.9;Kupffer cells: 28.7;Macrophages: 32.0;monocytes: 35.3;Plasma cells: 41.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 85.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 7.9;lymphoma: 3.5;Myeloma: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010546 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 73: B-cells - B-cell function" 1 "HPA010546: AB_1078268" "unprognostic (9.48e-2)" "unprognostic (6.01e-5)" "unprognostic (4.72e-3)" "unprognostic (3.04e-1)" "unprognostic (6.30e-2)" "unprognostic (2.80e-3)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (4.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-4)" "unprognostic (5.82e-2)" "unprognostic (3.56e-2)" "unprognostic (9.87e-2)" "unprognostic (8.94e-2)" CYSLTR2 "CysLT(2), CYSLT2R" ENSG00000152207 "Cysteinyl leukotriene receptor 2" Q9NS75 13 48653711-48711226 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.2;seminal vesicle: 15.3" "Cell type enriched" "Detected in some" 4 "monocytes: 103.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.6;thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "eosinophil: 89.7" "Lineage enriched" "Detected in many" 14 "granulocytes: 89.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;lymphoma: 3.1;Neuroblastoma: 2.9" HPA046528 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 29: Monocytes - Innate immune response" 4 "HPA046528: AB_2679687" "unprognostic (9.83e-3)" "unprognostic (2.72e-3)" "unprognostic (1.05e-2)" "unprognostic (6.81e-2)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.11e-1)" "unprognostic (7.41e-3)" "unprognostic (8.33e-2)" "unprognostic (1.83e-1)" "unprognostic (5.44e-2)" "unprognostic (5.93e-2)" "unprognostic (1.88e-3)" "unprognostic (3.79e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-2)" "unprognostic (1.18e-2)" CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 188.3;Endothelial cells: 164.8;Microglial cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.5" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.5" "Cancer enhanced" "Detected in some" "Bone cancer: 14.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" DAD1 OST2 ENSG00000129562 "Defender against cell death 1" P61803 14 22564907-22589224 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028882 Uncertain Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 77: Plasma cells - Protein processing" Cytosol "Endoplasmic reticulum" "HPA028882: AB_10602214" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.02e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (9.43e-3)" "unprognostic (3.06e-2)" "unprognostic (6.09e-2)" "unprognostic (1.99e-2)" "unprognostic (9.64e-2)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-3)" DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468713-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 118.4;Extravillous trophoblasts: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 84000000 "Cluster 29: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" DAGLA "C11orf11, DAGLALPHA, KIAA0659, NSDDR" ENSG00000134780 "Diacylglycerol lipase alpha" Q9Y4D2 11 61680391-61747001 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Excitatory neurons: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062497, CAB078793" Approved Supported NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" 9 "CAB078793: , HPA062497: AB_2684784" "unprognostic (2.53e-3)" "unprognostic (1.85e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (1.23e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-4)" "unprognostic (2.22e-2)" "unprognostic (2.29e-3)" "unprognostic (3.99e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.14e-2)" DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 29: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 58: Macrophages - Innate immune response" 2 "Plasma membrane" Nucleoplasm "HPA069377: AB_2686132" "unprognostic (2.39e-1)" "unprognostic (4.61e-2)" "unprognostic (2.13e-3)" "unprognostic (1.42e-1)" "unprognostic (9.04e-3)" "unprognostic (3.68e-2)" "unprognostic (1.78e-3)" "unprognostic (2.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (7.18e-5)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (2.18e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.81e-2)" DAPK1 DAPK ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708634 "Cancer-related genes, Enzymes, Human disease related genes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 131.9;Excitatory neurons: 116.2;Inhibitory neurons: 149.1;Mesothelial cells: 120.0;monocytes: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.7;eosinophil: 8.7;intermediate monocyte: 14.0;myeloid DC: 4.8;non-classical monocyte: 15.3;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 56 "dendritic cells: 6.2;granulocytes: 8.7;monocytes: 15.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003516, CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 9 Centrosome "CAB037302: AB_1078622, HPA003516: , HPA040472: AB_2677001, HPA048436: AB_2680390" "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 48.4;thyroid gland: 40.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 91.4;Late spermatids: 111.3;Oligodendrocytes: 92.9;Proximal enterocytes: 53.4" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "basophil: 64.8;eosinophil: 138.6;neutrophil: 39.2" "Lineage enriched" "Detected in many" 26 "granulocytes: 138.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" 1 "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028569 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 2 Cytosol Nucleoplasm "HPA028569: AB_10794319" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 192.1;esophagus: 235.2;skin 1: 291.4" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 234.4;Basal squamous epithelial cells: 307.4;Muller glia cells: 856.4;Secretory cells: 481.9;Squamous epithelial cells: 802.3;Suprabasal keratinocytes: 328.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 11 "prostate cancer: 275.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: AB_2679870, HPA058635: AB_2732625" "unprognostic (3.95e-5)" "prognostic favorable (8.43e-4)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (8.59e-2)" "unprognostic (5.24e-2)" "unprognostic (4.59e-2)" "unprognostic (2.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-3)" "unprognostic (4.09e-2)" "unprognostic (6.68e-2)" "unprognostic (3.00e-2)" "unprognostic (2.30e-3)" DCAF17 "C2orf37, FLJ13096" ENSG00000115827 "DDB1 and CUL4 associated factor 17" Q5H9S7 2 171434217-171485052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Deafness, Diabetes mellitus, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053339, HPA055040" Uncertain Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA053339: AB_2682119, HPA055040: AB_2682680" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "unprognostic (5.98e-2)" "unprognostic (5.60e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-3)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.12e-2)" "unprognostic (1.41e-1)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.10e-4)" "unprognostic (2.79e-2)" DCAKD FLJ22955 ENSG00000172992 "Dephospho-CoA kinase domain containing" Q8WVC6 17 45023338-45061131 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060997 Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA060997: AB_2797262" "unprognostic (1.32e-2)" "unprognostic (4.79e-3)" "unprognostic (9.71e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.13e-1)" "unprognostic (8.24e-3)" "unprognostic (7.57e-2)" "unprognostic (6.05e-3)" "unprognostic (4.10e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-3)" "unprognostic (4.00e-2)" "unprognostic (6.55e-2)" "unprognostic (5.10e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "unprognostic (1.82e-2)" DCBLD1 "dJ94G16.1, MGC46341" ENSG00000164465 "Discoidin, CUB and LCCL domain containing 1" Q8N8Z6 6 117453817-117569858 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 37.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059667 Approved Approved Cytosol NA NA 22000000 "Cluster 11: T-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol "HPA059667: AB_2684099" "unprognostic (1.00e-1)" "prognostic unfavorable (6.44e-5)" "unprognostic (1.08e-1)" "unprognostic (3.23e-3)" "unprognostic (2.47e-1)" "unprognostic (2.29e-3)" "unprognostic (1.53e-2)" "unprognostic (5.94e-3)" "unprognostic (3.74e-2)" "unprognostic (8.99e-2)" "unprognostic (5.69e-3)" "unprognostic (6.33e-2)" "prognostic unfavorable (8.57e-8)" "unprognostic (6.99e-2)" "unprognostic (4.72e-2)" "unprognostic (7.44e-2)" "unprognostic (1.36e-1)" DCBLD2 "CLCP1, ESDN" ENSG00000057019 "Discoidin, CUB and LCCL domain containing 2" Q96PD2 3 98795941-98901695 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.6;Sertoli cells: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016909 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 2200000 "Cluster 16: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA016909: AB_1847510" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-1)" "unprognostic (5.97e-3)" "unprognostic (9.29e-3)" "unprognostic (8.31e-3)" "unprognostic (1.06e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.32e-5)" "prognostic unfavorable (2.87e-4)" "unprognostic (7.76e-2)" "unprognostic (3.93e-2)" "unprognostic (1.59e-3)" DCC "IGDCC1, NTN1R1" ENSG00000187323 "DCC netrin 1 receptor" P43146 18 52340197-53535903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;testis: 7.4" "Cell type enhanced" "Detected in some" "Early spermatids: 178.1;Excitatory neurons: 423.6;Inhibitory neurons: 435.6;Late spermatids: 187.7;Oligodendrocyte precursor cells: 1225.4" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 6.9;Myeloma: 23.2" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055376, HPA069552" Enhanced Approved "Golgi apparatus" NA NA 64000 "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 76: Oligodendrocyte precursor - Unknown function" 5 "Golgi apparatus" "HPA055376: AB_2682798, HPA069552: AB_2686151" "unprognostic (1.96e-3)" "unprognostic (1.69e-2)" "unprognostic (3.13e-1)" "unprognostic (3.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-3)" "unprognostic (2.59e-1)" "unprognostic (5.59e-2)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (8.22e-4)" "unprognostic (4.14e-2)" "unprognostic (1.27e-4)" "unprognostic (7.21e-2)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (2.69e-3)" DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.1;Endometrial stromal cells: 15.2;Endothelial cells: 27.6;Fibroblasts: 17.8;Lymphatic endothelial cells: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 12.8;Neuroblastoma: 28.7" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 59.8;Early spermatids: 17.6;Excitatory neurons: 29.2;Inhibitory neurons: 12.6;Late spermatids: 21.9;Microglial cells: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131382 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.4" "Group enriched" "Detected in many" 6 "Excitatory neurons: 936.9;Inhibitory neurons: 637.4" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 104.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712421-36764553 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;testis: 2.7" "Cell type enriched" "Detected in some" 10 "Early spermatids: 74.6" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040685, HPA053234" Approved Approved Vesicles,Cytosol NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 18: Early spermatids - Unknown function" Cytosol Vesicles "HPA040685: AB_2732487, HPA053234: " "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" DCP1B FLJ31638 ENSG00000151065 "Decapping mRNA 1B" Q8IZD4 12 1946053-2004535 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.4;Early spermatids: 58.9;Oligodendrocyte precursor cells: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 5 "T-cells: 27.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039709 Approved Supported Vesicles,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 "Vesicles, Cytosol" "HPA039709: AB_10672901" "unprognostic (9.60e-2)" "unprognostic (7.19e-3)" "unprognostic (4.37e-3)" "unprognostic (2.13e-1)" "unprognostic (7.00e-2)" "unprognostic (1.08e-1)" "unprognostic (8.94e-2)" "unprognostic (3.26e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-2)" "unprognostic (5.87e-2)" "unprognostic (1.83e-1)" "unprognostic (1.08e-2)" "unprognostic (3.98e-2)" "unprognostic (1.46e-1)" "unprognostic (1.84e-2)" "unprognostic (7.42e-2)" DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.5;skin 1: 3.0;testis: 6.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.5;Early spermatids: 39.5;Late spermatids: 17.6;Rod photoreceptor cells: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060314 Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" "HPA060314: AB_2684250" "unprognostic (1.44e-1)" "unprognostic (7.66e-2)" "unprognostic (3.77e-2)" "unprognostic (1.05e-4)" "unprognostic (3.58e-2)" "unprognostic (8.75e-4)" "unprognostic (1.46e-2)" "unprognostic (2.66e-1)" "unprognostic (6.01e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.89e-2)" "unprognostic (8.33e-15)" "unprognostic (7.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.38e-1)" "unprognostic (1.23e-1)" DCT "TRP-2, TRP2, TYRP2" ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis" Isomerase "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 104.7" "Cell type enriched" "Detected in some" 56 "Melanocytes: 9127.0" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 26 "skin cancer: 361.4" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 82: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" DDOST "KIAA0115, OST, OST48, WBP1" ENSG00000244038 "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit" P39656 1 20651767-20661544 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 349.2;Plasma cells: 384.0;Syncytiotrophoblasts: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009746, HPA046841, HPA052867" Supported Supported "Endoplasmic reticulum" NA NA 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "CAB009746: AB_2092075, HPA046841: AB_2679834, HPA052867: AB_2681977" "unprognostic (8.57e-3)" "unprognostic (1.35e-2)" "unprognostic (1.57e-2)" "prognostic favorable (5.99e-4)" "unprognostic (1.62e-1)" "prognostic unfavorable (4.88e-4)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (2.70e-2)" "unprognostic (3.59e-2)" "unprognostic (3.72e-1)" "prognostic unfavorable (9.05e-7)" "unprognostic (1.07e-1)" "unprognostic (2.98e-1)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" Receptor NA NA 4400000 "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 84.7;Fibroblasts: 128.6;Leydig cells: 62.8;Mesothelial cells: 69.7;Peritubular cells: 85.6;Smooth muscle cells: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 44.3" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 6 "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" DDX3X "CAP-Rf, DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 892.9;monocytes: 762.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 80: Non-specific - Transcription" 12 Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Isomerase, Oxidoreductase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 521.1" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 272.8;Suprabasal keratinocytes: 210.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" Mitochondria "HPA076422: AB_2686799" "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (2.53e-4)" DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.0;intestine: 33.8;skin 1: 52.4" "Cell type enhanced" "Detected in many" "Oocytes: 95.6;Proximal enterocytes: 315.6;Squamous epithelial cells: 104.6;Suprabasal keratinocytes: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.7;memory B-cell: 10.9;naive B-cell: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.7" "Cancer enhanced" "Detected in many" "breast cancer: 20.5;colorectal cancer: 11.3;Gastric cancer: 11.7" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" DENND1A "FAM31A, FLJ21129, KIAA1608" ENSG00000119522 "DENN domain containing 1A" Q8TEH3 9 123379654-123930152 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 245.5;Excitatory neurons: 181.8;Inhibitory neurons: 168.4;Late spermatids: 83.5;Microglial cells: 170.0;Oligodendrocyte precursor cells: 155.2;Oligodendrocytes: 135.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 11.4;granulocytes: 14.0;monocytes: 19.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020481 Approved Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 47: Astrocytes - Unknown function" 2 "Vesicles, Cytosol" "HPA020481: AB_2092106" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-1)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.19e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (2.48e-3)" "unprognostic (5.63e-2)" "prognostic favorable (4.11e-5)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (4.31e-2)" DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 97.8;Inhibitory neurons: 133.0;Langerhans cells: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" Cytosol "Nuclear speckles" "HPA042586: AB_2678064" "unprognostic (8.79e-2)" "unprognostic (1.58e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (7.79e-3)" "unprognostic (3.99e-2)" "unprognostic (3.13e-2)" "unprognostic (5.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.5;Microglial cells: 76.0;monocytes: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.7;neutrophil: 40.5" "Group enriched" "Detected in many" 5 "granulocytes: 40.5;monocytes: 10.1" "Cancer enhanced" "Detected in all" "Leukemia: 67.4" "Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" DENND4B KIAA0476 ENSG00000198837 "DENN domain containing 4B" O75064 1 153929501-153946718 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040188, HPA071133" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA040188: AB_10671168, HPA071133: AB_2732173" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (1.59e-2)" "unprognostic (9.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-3)" "prognostic unfavorable (4.14e-4)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.18e-5)" "unprognostic (2.21e-1)" "prognostic unfavorable (9.27e-9)" "unprognostic (4.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.56e-3)" DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 143.8;monocytes: 392.4;Oligodendrocytes: 267.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "Golgi apparatus, Vesicles" "HPA052923: AB_2681989, HPA055009: AB_2682669" "unprognostic (5.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.03e-1)" "unprognostic (3.48e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.15e-2)" "unprognostic (3.10e-1)" "prognostic unfavorable (1.14e-6)" "unprognostic (9.86e-3)" "unprognostic (1.03e-1)" "unprognostic (4.32e-1)" "unprognostic (1.40e-2)" DENND5B MGC24039 ENSG00000170456 "DENN domain containing 5B" Q6ZUT9 12 31382226-31591136 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 144.9;Excitatory neurons: 210.0;Inhibitory neurons: 236.3;Oligodendrocyte precursor cells: 135.4;Oligodendrocytes: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 52.8" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038865 Approved Approved Microtubules NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 8: Neurons - Neuronal signaling" Microtubules "HPA038865: AB_2676245" "unprognostic (5.41e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (7.23e-2)" "unprognostic (2.13e-1)" "unprognostic (1.16e-2)" "unprognostic (4.96e-2)" "unprognostic (3.14e-1)" "unprognostic (8.27e-2)" "unprognostic (5.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (2.60e-2)" DERL1 "DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577" ENSG00000136986 "Derlin 1" Q9BUN8 8 123013170-123042302 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016562, CAB037269" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Non-specific - Unknown function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 25 "Endoplasmic reticulum" "CAB037269: AB_609868, HPA016562: AB_1847611" "prognostic unfavorable (2.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (9.48e-2)" "unprognostic (4.21e-3)" "unprognostic (2.76e-1)" "unprognostic (1.28e-3)" "unprognostic (4.42e-2)" "unprognostic (5.38e-2)" "unprognostic (1.41e-3)" "unprognostic (4.35e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.88e-3)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 8 "Endoplasmic reticulum" "CAB037287: AB_1078641, HPA048957: AB_2680570, HPA056551: AB_2683171" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (5.83e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.51e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.17e-1)" "unprognostic (1.12e-3)" "unprognostic (1.73e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (3.73e-1)" "unprognostic (2.91e-2)" DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;pancreas: 59.1;salivary gland: 49.6" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1530.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.8" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.8" "Cancer enriched" "Detected in many" 7 "Myeloma: 39.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 14 Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" DEXI MYLE ENSG00000182108 "Dexi homolog" O95424 16 10928891-10942468 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041511 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" 8 "Nuclear speckles" Cytosol "HPA041511: AB_10796675" "unprognostic (4.14e-1)" "unprognostic (8.52e-2)" "unprognostic (1.29e-1)" "unprognostic (9.70e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (1.19e-2)" "unprognostic (4.71e-2)" "unprognostic (3.20e-1)" "unprognostic (1.47e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.21e-2)" "unprognostic (1.33e-3)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.75e-2)" "unprognostic (1.83e-2)" DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.6" "Group enriched" "Detected in many" 5 "Distal enterocytes: 179.5;Proximal enterocytes: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 459.3;breast: 129.3;liver: 321.2;skin 1: 146.7" "Cell type enhanced" "Detected in many" "Early spermatids: 277.3;Hepatocytes: 103.0;Late spermatids: 95.1;Spermatocytes: 56.1;Spermatogonia: 46.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 138.1;neutrophil: 350.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 350.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 30.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 74: Neutrophils - Degranulation" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Human disease related genes, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 84000 "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA000873: AB_1847632" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (4.03e-2)" "unprognostic (1.33e-2)" "unprognostic (6.28e-2)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.86e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.72e-7)" "unprognostic (3.63e-2)" "unprognostic (2.29e-1)" "unprognostic (6.27e-2)" "unprognostic (6.28e-3)" DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 33.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 167.8;Cone photoreceptor cells: 151.2;Inhibitory neurons: 86.3;Rod photoreceptor cells: 165.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 28: Neuronal - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Bipolar cells - Visual perception" 2 "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1094.1;liver: 604.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 338.6;Alveolar cells type 2: 518.0;Hepatocytes: 825.3;Suprabasal keratinocytes: 287.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Hepatocytes - Metabolism" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 157.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 105.8;Basal respiratory cells: 76.4;Hepatocytes: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 103.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 132.4;Lymphatic endothelial cells: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 62: Hepatocytes - Metabolism" 2 Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 315.8" "Cell type enhanced" "Detected in many" "Late spermatids: 395.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 87.0;MAIT T-cell: 63.2;memory CD4 T-cell: 47.0;memory CD8 T-cell: 41.0;myeloid DC: 24.1;naive CD4 T-cell: 79.4;naive CD8 T-cell: 50.2;NK-cell: 41.2" "Group enriched" "Detected in many" 5 "dendritic cells: 24.1;NK-cells: 41.2;T-cells: 87.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favorable (2.65e-4)" "unprognostic (5.48e-2)" DHRS7B "CGI-93, DKFZp566O084, MGC8916, SDR32C1" ENSG00000109016 "Dehydrogenase/reductase 7B" Q6IAN0 17 21123364-21193265 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012132, HPA016873" Uncertain Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cell Junctions, Cytosol" "HPA012132: AB_1847658, HPA016873: AB_1847657" "unprognostic (1.90e-1)" "unprognostic (3.16e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.98e-8)" "unprognostic (9.83e-2)" "unprognostic (1.18e-1)" "unprognostic (3.46e-1)" "unprognostic (1.45e-1)" "unprognostic (5.02e-3)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.81e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.20e-2)" "unprognostic (6.26e-2)" "unprognostic (9.20e-2)" "unprognostic (3.97e-1)" DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 52.1;intestine: 68.1" "Cell type enhanced" "Detected in many" "Club cells: 153.0;Distal enterocytes: 194.3;Early spermatids: 184.0;Ionocytes: 253.3;Syncytiotrophoblasts: 443.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 259.3;eosinophil: 99.5;neutrophil: 77.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 259.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 144.7;pancreatic cancer: 82.9" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036491, HPA036667" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" DHX36 "DDX36, KIAA1488, MLEL1, RHAU" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324487 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 586.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035398, HPA035399" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Early spermatids - Spermatogenesis" 1 Nucleoplasm "Mitochondria, Cytosol" "HPA035398: , HPA035399: AB_10670115" "unprognostic (8.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (3.50e-3)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (5.09e-2)" "unprognostic (5.27e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.7;Excitatory neurons: 14.0;Gastric mucus-secreting cells: 13.6;Inhibitory neurons: 13.5;Oligodendrocytes: 14.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Supported Mitochondria NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 63: Testis - Spermatid development" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 25 Mitochondria "CAB003857: AB_365498, CAB016688: AB_1615783, HPA001825: AB_1857247" "unprognostic (3.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.38e-3)" "unprognostic (1.40e-3)" "unprognostic (5.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" DIO2 "SELENOY, SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 158.0;thyroid gland: 345.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 95.7;Endometrial stromal cells: 141.7;Extravillous trophoblasts: 586.4;Muller glia cells: 191.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 95.8;Brain cancer: 82.1" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 4: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101560139-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.2;placenta: 18.8" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "thalamus: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 8.1" "Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 6.1;hippocampal formation: 7.7" HPA073684 Supported Vesicles NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" DIP2A "C21orf106, Dip2, KIAA0184" ENSG00000160305 "Disco interacting protein 2 homolog A" Q14689 21 46458891-46570015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Ligase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 176.0;Oligodendrocytes: 133.1;Rod photoreceptor cells: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052516 Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 19: NK-cells - Adaptive immune response" 6 Nucleoplasm "HPA052516: AB_2681859" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (6.52e-2)" "unprognostic (3.88e-2)" "unprognostic (7.30e-2)" "prognostic favorable (9.35e-5)" "unprognostic (1.37e-1)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (3.86e-2)" "unprognostic (1.70e-2)" "unprognostic (6.05e-3)" "unprognostic (1.05e-1)" "unprognostic (8.08e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-3)" DIP2C KIAA0934 ENSG00000151240 "Disco interacting protein 2 homolog C" Q9Y2E4 10 274190-689668 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 118.9;Excitatory neurons: 212.0;Inhibitory neurons: 258.6;Oligodendrocyte precursor cells: 202.8;Oligodendrocytes: 392.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030264, HPA059325" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 79: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 69: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" Vesicles "HPA030264: AB_10600903, HPA059325: AB_2683979" "unprognostic (1.72e-2)" "unprognostic (3.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (8.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.16e-2)" "unprognostic (1.58e-1)" "unprognostic (2.00e-1)" "unprognostic (6.28e-3)" "unprognostic (5.94e-2)" "unprognostic (3.65e-2)" "prognostic favorable (2.46e-6)" "unprognostic (8.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-3)" "unprognostic (9.10e-3)" DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 78.3;Excitatory neurons: 109.8;Inhibitory neurons: 139.7;Oligodendrocyte precursor cells: 123.6;Oligodendrocytes: 150.2;Plasma cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 81.6" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 15: Non-specific - Mixed function" Cytosol Nucleoplasm "HPA015718: AB_1848405, HPA017281: AB_1848406" "prognostic favorable (8.96e-4)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (1.50e-3)" "unprognostic (1.43e-1)" "unprognostic (3.77e-3)" "unprognostic (3.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.45e-7)" "unprognostic (1.26e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-1)" "unprognostic (1.66e-2)" DIPK1B "C9orf136, FAM69B, MGC20262" ENSG00000165716 "Divergent protein kinase domain 1B" Q5VUD6 9 136712572-136724742 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 54.0;Endothelial cells: 37.1;Glandular and luminal cells: 26.6;Horizontal cells: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 1.0;naive B-cell: 2.8;plasmacytoid DC: 1.0" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054443 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 34: B-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA054443: AB_2682489" "unprognostic (2.78e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (1.77e-5)" "unprognostic (3.82e-1)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (6.80e-2)" "unprognostic (2.10e-2)" "prognostic favorable (9.48e-5)" "unprognostic (2.77e-1)" "unprognostic (6.67e-3)" "unprognostic (4.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.84e-1)" "unprognostic (2.78e-1)" DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 195.0;Oligodendrocyte precursor cells: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 14: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" DISP2 "C15orf36, DISPB, HsT16908, KIAA1742, LINC00594" ENSG00000140323 "Dispatched RND transporter family member 2" A7MBM2 15 40358219-40378621 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 27.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.7;Distal enterocytes: 21.6;Enteroendocrine cells: 14.6;Horizontal cells: 34.6;Intestinal goblet cells: 18.1;Proximal enterocytes: 12.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059903 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoplasm, Vesicles" "HPA059903: AB_2684156" "unprognostic (3.43e-4)" "unprognostic (7.65e-3)" "unprognostic (4.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (3.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" "unprognostic (4.47e-8)" "unprognostic (1.96e-1)" "unprognostic (3.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.71e-1)" DISP3 "KIAA1337, PTCHD2" ENSG00000204624 "Dispatched RND transporter family member 3" Q9P2K9 1 11479155-11537551 "Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Differentiation, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 8.5;pituitary gland: 3.4;retina: 4.4;testis: 6.1" "Cell type enhanced" "Detected in some" "Astrocytes: 28.8;Early spermatids: 19.0;Horizontal cells: 51.6;Late spermatids: 42.3;Rod photoreceptor cells: 15.6" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054579 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm Cytosol "HPA054579: AB_2682529" "unprognostic (4.93e-2)" "unprognostic (2.23e-2)" "unprognostic (1.61e-1)" "unprognostic (9.55e-3)" "unprognostic (1.80e-1)" "unprognostic (2.73e-1)" "unprognostic (6.12e-2)" "unprognostic (7.75e-2)" "unprognostic (3.62e-1)" "unprognostic (1.08e-1)" "unprognostic (4.34e-3)" "unprognostic (4.86e-2)" "unprognostic (3.80e-2)" "unprognostic (3.88e-1)" "unprognostic (7.06e-2)" "unprognostic (1.79e-4)" "unprognostic (1.34e-1)" DLK1 "Delta1, FA1, pG2, Pref-1, ZOG" ENSG00000185559 "Delta like non-canonical Notch ligand 1" P80370 14 100725705-100738224 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 1289.3;pituitary gland: 752.3;placenta: 1576.5" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 229.9;Leydig cells: 1353.1;Peritubular cells: 158.9;Smooth muscle cells: 340.3" "Cancer enhanced" "Detected in many" "liver cancer: 28.1;testis cancer: 25.4" "Region enhanced" "Detected in many" "hypothalamus: 353.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 489.9;Rhabdoid: 329.1" "Region enhanced" "Detected in many" "hypothalamus: 111.6" "Group enriched" "Detected in many" 5 "hypothalamus: 53.8;midbrain: 203.8" "CAB005872, HPA062262" Enhanced Approved "Golgi apparatus" NA NA 2600000 "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 1 "Golgi apparatus" "CAB005872: AB_731965, HPA062262: AB_2684729" "unprognostic (2.16e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (4.89e-3)" "unprognostic (5.75e-2)" "unprognostic (1.87e-2)" "unprognostic (1.12e-1)" "unprognostic (5.24e-1)" "unprognostic (3.11e-2)" "unprognostic (6.57e-2)" DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 11.9;prostate: 12.5;skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.0;Basal respiratory cells: 51.0;Basal squamous epithelial cells: 44.1;Breast myoepithelial cells: 31.8;Salivary duct cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.6" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 80: Non-specific - Endocytosis" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: AB_2684454, HPA068672: AB_2686017, HPA070955: " "unprognostic (4.65e-5)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (9.68e-4)" "unprognostic (2.87e-1)" "unprognostic (3.80e-1)" "unprognostic (4.19e-3)" "unprognostic (1.65e-1)" "unprognostic (2.65e-3)" "unprognostic (4.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (9.27e-12)" "unprognostic (7.71e-4)" "unprognostic (8.92e-2)" "unprognostic (1.55e-1)" "unprognostic (6.43e-2)" DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.6" "Cell type enhanced" "Detected in many" "Adipocytes: 85.9;Basal keratinocytes: 54.2;Basal squamous epithelial cells: 87.1;Intestinal goblet cells: 84.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3" "Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 28.1" "Cell type enhanced" "Detected in some" "Oligodendrocyte precursor cells: 23.1;Oocytes: 105.9;Spermatogonia: 42.1" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.9;skin cancer: 27.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 67: Spermatogonia - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 63.8;Endothelial cells: 50.5;Intestinal goblet cells: 30.6;Lymphatic endothelial cells: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.8;lung cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly component 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 451.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014585 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.8;Skeletal myocytes: 66.4;Smooth muscle cells: 47.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Smooth muscle cells - Muscle contraction" 3 Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 40.1;lymphoid tissue: 18.6;parathyroid gland: 40.2;skeletal muscle: 12.6" "Cell type enriched" "Detected in some" 11 "Distal tubular cells: 116.8" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 5.8" "Kidney - Intercalated cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 1 "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" DMXL2 "DFNA71, KIAA0856, RC3" ENSG00000104093 "Dmx like 2" Q8TDJ6 15 51447711-51622833 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Diabetes mellitus, Disease variant, Epilepsy, Hypogonadotropic hypogonadism, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.2;Inhibitory neurons: 117.8;Kupffer cells: 84.3;Macrophages: 102.6;monocytes: 175.0;Oligodendrocyte precursor cells: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.8;intermediate monocyte: 2.2;neutrophil: 2.2;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 4 "granulocytes: 2.2;monocytes: 2.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039375 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Neuronal - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA039375: AB_10673610" "unprognostic (5.66e-2)" "unprognostic (9.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-2)" "unprognostic (8.38e-2)" "unprognostic (3.39e-1)" "unprognostic (2.32e-1)" "unprognostic (3.67e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (1.09e-1)" "unprognostic (1.67e-1)" "unprognostic (8.60e-3)" "unprognostic (2.70e-2)" DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717744-7833742 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 12.6;parathyroid gland: 10.2;retina: 20.1" "Group enriched" "Detected in some" 9 "Ciliated cells: 41.5;Rod photoreceptor cells: 130.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA067103 Enhanced Approved Microtubules NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" Microtubules "HPA067103: AB_2685778" "unprognostic (2.03e-2)" "unprognostic (1.79e-2)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-1)" "unprognostic (7.50e-3)" "unprognostic (1.29e-2)" "unprognostic (8.28e-2)" "unprognostic (2.51e-3)" "unprognostic (1.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (8.74e-3)" "unprognostic (4.60e-2)" DNAJB12 "DJ10, FLJ20027" ENSG00000148719 "DnaJ heat shock protein family (Hsp40) member B12" Q9NXW2 10 72332830-72355149 "Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 233.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010642, HPA072702" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 63: Late spermatids - Spermatogenesis" "Nuclear membrane, Endoplasmic reticulum" "HPA010642: AB_1078692, HPA072702: " "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (6.01e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.73e-2)" "unprognostic (5.60e-2)" "unprognostic (8.85e-3)" "unprognostic (1.95e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (4.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.87e-1)" DNAJB14 FLJ14281 ENSG00000164031 "DnaJ heat shock protein family (Hsp40) member B14" Q8TBM8 4 99896248-99946618 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036016 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "HPA036016: AB_10670594" "unprognostic (1.90e-2)" "unprognostic (1.68e-1)" "unprognostic (9.04e-3)" "unprognostic (5.33e-2)" "unprognostic (2.10e-1)" "unprognostic (1.71e-1)" "unprognostic (2.35e-2)" "unprognostic (4.34e-2)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (2.75e-2)" "prognostic favorable (2.12e-6)" "unprognostic (1.42e-1)" "unprognostic (1.07e-1)" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" DNAJC1 "DNAJL1, ERdj1, MTJ1" ENSG00000136770 "DnaJ heat shock protein family (Hsp40) member C1" Q96KC8 10 21756548-22003769 "Predicted membrane proteins, Transcription factors" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 266.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 135.5" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013432 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 8 "Endoplasmic reticulum" "HPA013432: AB_1847797" "unprognostic (7.00e-2)" "unprognostic (9.81e-2)" "unprognostic (3.61e-1)" "unprognostic (5.12e-2)" "unprognostic (5.51e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (3.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.46e-2)" "unprognostic (1.09e-1)" "unprognostic (9.36e-2)" "prognostic favorable (2.33e-4)" "unprognostic (4.44e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-2)" "unprognostic (2.22e-2)" DNAJC10 "ERdj5, PDIA19" ENSG00000077232 "DnaJ heat shock protein family (Hsp40) member C10" Q8IXB1 2 182716255-182794464 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 111.2" "Cell type enhanced" "Detected in all" "Early spermatids: 244.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031111 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Plasma cells - Protein processing" "HPA031111: AB_10601211" "unprognostic (3.29e-2)" "unprognostic (5.20e-3)" "unprognostic (3.10e-3)" "prognostic favorable (6.42e-5)" "unprognostic (1.89e-1)" "unprognostic (1.18e-1)" "unprognostic (4.34e-3)" "unprognostic (1.82e-2)" "unprognostic (1.54e-2)" "unprognostic (4.34e-2)" "unprognostic (2.29e-1)" "unprognostic (9.76e-2)" "prognostic unfavorable (2.19e-7)" "unprognostic (2.91e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (7.27e-4)" "unprognostic (2.87e-2)" DNAJC11 FLJ10737 ENSG00000007923 "DnaJ heat shock protein family (Hsp40) member C11" Q9NVH1 1 6634168-6701924 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023707, HPA028705" Uncertain Supported Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "HPA023707: , HPA028705: AB_10603662" "unprognostic (3.74e-2)" "unprognostic (3.19e-2)" "unprognostic (4.06e-2)" "unprognostic (6.05e-3)" "unprognostic (9.55e-2)" "unprognostic (6.65e-2)" "unprognostic (4.38e-3)" "unprognostic (6.10e-2)" "unprognostic (6.34e-2)" "unprognostic (2.89e-1)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.30e-2)" "unprognostic (1.76e-1)" "unprognostic (9.77e-2)" "unprognostic (1.04e-1)" DNAJC13 "KIAA0678, RME8" ENSG00000138246 "DnaJ heat shock protein family (Hsp40) member C13" O75165 3 132417502-132539032 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036923, HPA036924" Approved Supported Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 51: Thyroid gland - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" Vesicles Cytosol "HPA036923: AB_10672480, HPA036924: AB_2675386" "unprognostic (3.35e-3)" "unprognostic (7.47e-2)" "unprognostic (9.16e-2)" "unprognostic (1.20e-2)" "unprognostic (9.71e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (3.68e-2)" "unprognostic (3.38e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (8.36e-4)" "unprognostic (1.92e-1)" "unprognostic (4.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" DNAJC14 "DNAJ, DRIP78, FLJ32792, HDJ3, LIP6" ENSG00000135392 "DnaJ heat shock protein family (Hsp40) member C14" Q6Y2X3 12 55820960-55830824 "Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Stomach - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017653 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" "HPA017653: AB_1847799" "unprognostic (2.54e-2)" "unprognostic (1.77e-2)" "unprognostic (1.47e-1)" "unprognostic (1.90e-1)" "unprognostic (6.04e-2)" "unprognostic (3.14e-2)" "unprognostic (6.91e-3)" "unprognostic (6.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.63e-1)" "unprognostic (4.34e-2)" "unprognostic (3.89e-3)" "unprognostic (4.73e-2)" "unprognostic (7.98e-2)" "unprognostic (9.17e-2)" "unprognostic (8.92e-2)" DNAJC16 KIAA0962 ENSG00000116138 "DnaJ heat shock protein family (Hsp40) member C16" Q9Y2G8 1 15526813-15592379 "Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043643 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" Vesicles "HPA043643: AB_10796794" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "prognostic favorable (6.77e-4)" "unprognostic (4.52e-2)" "unprognostic (5.51e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (4.28e-2)" "unprognostic (2.35e-2)" "unprognostic (3.74e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" "unprognostic (5.38e-2)" "unprognostic (4.70e-2)" DNAJC18 MGC29463 ENSG00000170464 "DnaJ heat shock protein family (Hsp40) member C18" Q9H819 5 139408588-139444491 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.7" "Group enriched" "Detected in many" 19 "Early spermatids: 460.2;Late spermatids: 1343.8" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036538, HPA060154" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Late spermatids - Unknown function" "Cell Junctions" Cytosol "HPA036538: AB_10670802, HPA060154: AB_2684212" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (2.73e-3)" "unprognostic (8.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "prognostic favorable (5.89e-4)" "unprognostic (8.09e-2)" "unprognostic (1.69e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (6.96e-2)" "unprognostic (1.97e-2)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 23.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.0;Distal enterocytes: 34.4;Enteroendocrine cells: 32.6;Hepatocytes: 38.1;Intestinal goblet cells: 31.4;Mesothelial cells: 27.6;Paneth cells: 33.6;Proximal enterocytes: 55.9;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" DNAJC25 bA16L21.2.1 ENSG00000059769 "DnaJ heat shock protein family (Hsp40) member C25" Q9H1X3 9 111631334-111654351 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 31.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019122 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 43: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA019122: AB_1853155" "unprognostic (3.07e-1)" "unprognostic (7.42e-2)" "unprognostic (8.94e-3)" "prognostic favorable (3.73e-4)" "unprognostic (2.08e-2)" "unprognostic (5.66e-2)" "unprognostic (1.60e-2)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (9.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.09e-2)" "unprognostic (2.52e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-1)" "unprognostic (8.30e-2)" "unprognostic (5.19e-2)" DNAJC30 WBSCR18 ENSG00000176410 "DnaJ heat shock protein family (Hsp40) member C30" Q96LL9 7 73680918-73683453 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" Chaperone "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 104.4;Late spermatids: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017318 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Testis - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 23 "HPA017318: AB_1858788" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (2.66e-2)" "unprognostic (4.53e-1)" "unprognostic (3.93e-2)" "unprognostic (2.85e-3)" "unprognostic (4.60e-2)" "prognostic favorable (4.91e-8)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" DNAJC4 "HSPF2, MCG18" ENSG00000110011 "DnaJ heat shock protein family (Hsp40) member C4" Q9NNZ3 11 64230278-64234286 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 234.2" "Cell type enriched" "Detected in all" 7 "Late spermatids: 3325.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011947 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 36: Late spermatids - Unknown function" 3 "HPA011947: AB_1847803" "unprognostic (8.99e-3)" "unprognostic (2.28e-2)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.95e-2)" "unprognostic (1.15e-1)" "unprognostic (5.20e-2)" "unprognostic (8.99e-2)" "unprognostic (1.56e-2)" "unprognostic (7.69e-2)" "unprognostic (5.44e-3)" "unprognostic (1.73e-3)" "unprognostic (1.07e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.47e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (2.69e-1)" DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.4" "Cell type enhanced" "Detected in all" "Late spermatids: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Late spermatids - Spermatogenesis" 3 "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" DNAJC5G "CSP-gamma, FLJ40417" ENSG00000163793 "DnaJ heat shock protein family (Hsp40) member C5 gamma" Q8N7S2 2 27275433-27281499 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 45.7;testis: 22.1" "Group enriched" "Detected in some" 4 "Early spermatids: 63.2;Late spermatids: 77.0;Spermatocytes: 77.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041445 Approved NA NA "Cluster 63: Testis - Spermatid development" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA041445: AB_2677485" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (2.26e-1)" "unprognostic (3.99e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-1)" "unprognostic (4.06e-1)" "unprognostic (1.75e-4)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" "unprognostic (7.67e-2)" "unprognostic (1.97e-2)" DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 70.7;brain: 128.1;choroid plexus: 148.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 100.7;Horizontal cells: 166.8;Inhibitory neurons: 318.5;Oligodendrocyte precursor cells: 408.9;Oligodendrocytes: 230.6;Serous glandular cells: 234.6" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 106.9" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0;Late spermatids: 497.7;Proximal enterocytes: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 11: Late spermatids - Unknown function" 2 Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" DOK7 "C4orf25, Dok-7, FLJ33718, FLJ39137" ENSG00000175920 "Docking protein 7" Q18PE1 4 3463306-3501473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.5;skeletal muscle: 28.5" "Cell type enhanced" "Detected in many" "B-cells: 7.6;Basal prostatic cells: 6.4;Cardiomyocytes: 11.7;Late spermatids: 9.0;Oocytes: 10.3;Secretory cells: 10.0;Skeletal myocytes: 8.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "memory B-cell: 3.4;naive B-cell: 2.3;NK-cell: 1.9" "Group enriched" "Detected in many" 16 "B-cells: 3.4;NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059449, HPA062780" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 73: B-cells - B-cell function" 2 Nucleoplasm Mitochondria "HPA059449: AB_2684023, HPA062780: AB_2732688" "prognostic favorable (8.45e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-2)" "prognostic favorable (2.19e-4)" "unprognostic (5.96e-2)" "unprognostic (6.80e-3)" "unprognostic (1.05e-2)" "unprognostic (9.54e-2)" "unprognostic (1.12e-2)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-4)" "unprognostic (4.61e-3)" "unprognostic (5.09e-1)" "unprognostic (3.16e-2)" "prognostic favorable (1.28e-4)" DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Mixed function" 19 "Nucleoplasm, Nucleoli" Cytosol "HPA066767: AB_2732751, HPA068706: AB_2732118" "unprognostic (6.35e-2)" "unprognostic (2.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-3)" "unprognostic (3.55e-1)" "unprognostic (2.81e-3)" "unprognostic (8.90e-3)" "unprognostic (3.26e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-2)" "prognostic favorable (5.53e-4)" "unprognostic (3.20e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.88e-5)" "unprognostic (6.13e-3)" DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081111-129090438 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 49.8;Erythroid cells: 37.3;Spermatocytes: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 52: Non-specific - Cell proliferation" 2 "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: AB_2676570, HPA049033: AB_2680608" "unprognostic (9.90e-3)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.22e-4)" "unprognostic (4.00e-2)" "unprognostic (5.93e-3)" "prognostic favorable (2.17e-4)" "unprognostic (1.25e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.77e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (8.83e-2)" DOP1A "dJ202D23.2, DOPEY1, KIAA1117" ENSG00000083097 "DOP1 leucine zipper like protein A" Q5JWR5 6 83067666-83171350 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 73.7;Excitatory neurons: 155.6;Inhibitory neurons: 141.8;Oligodendrocyte precursor cells: 132.5;Oligodendrocytes: 116.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027902, HPA027904" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm Vesicles "HPA027902: AB_10600003, HPA027904: AB_10600877" "unprognostic (7.18e-2)" "unprognostic (3.91e-1)" "unprognostic (6.11e-2)" "unprognostic (6.05e-3)" "unprognostic (8.21e-3)" "unprognostic (1.36e-2)" "unprognostic (3.32e-1)" "unprognostic (1.02e-2)" "unprognostic (2.84e-1)" "unprognostic (2.47e-1)" "prognostic favorable (7.36e-4)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" DPAGT1 "ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT" ENSG00000172269 "Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1" Q9H3H5 11 119096025-119108331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053878 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 1 "HPA053878: AB_2682288" "unprognostic (1.66e-2)" "unprognostic (3.14e-3)" "unprognostic (1.76e-1)" "unprognostic (7.83e-3)" "unprognostic (6.50e-2)" "unprognostic (8.53e-3)" "prognostic unfavorable (2.03e-5)" "unprognostic (2.52e-1)" "unprognostic (3.95e-1)" "unprognostic (9.05e-2)" "unprognostic (2.08e-2)" "unprognostic (7.12e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (1.08e-2)" "unprognostic (2.52e-2)" "unprognostic (4.57e-2)" DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.0;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 43.1;Kupffer cells: 44.9;Langerhans cells: 27.3;Macrophages: 27.9;monocytes: 71.8;Syncytiotrophoblasts: 67.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 411.4;eosinophil: 844.3;neutrophil: 361.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 844.3" "Cancer enriched" "Detected in some" 5 "Leukemia: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 16.6" HPA035644 Approved NA NA 330000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 45.7" "Group enriched" "Detected in some" 7 "Spermatocytes: 335.4;Spermatogonia: 226.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 6.7;NK-cell: 1.8" "Group enriched" "Detected in many" 8 "granulocytes: 6.7;NK-cells: 1.8" "Cancer enhanced" "Detected in some" "cervical cancer: 17.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA031870, HPA058607" Enhanced NA NA 27000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA031870: AB_2674079, HPA058607: AB_2683775" "unprognostic (9.93e-2)" "unprognostic (2.81e-3)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.37e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.49e-3)" "unprognostic (9.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-3)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.51e-1)" DPM2 "MGC111193, MGC21559" ENSG00000136908 "Dolichyl-phosphate mannosyltransferase subunit 2, regulatory" O94777 9 127935099-127937854 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064623 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 1: Erythroid cells - Oxygen transport" 4 "HPA064623: AB_2685303" "unprognostic (8.30e-3)" "unprognostic (1.07e-2)" "unprognostic (9.84e-3)" "prognostic favorable (2.20e-4)" "unprognostic (3.67e-1)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.91e-1)" "unprognostic (1.37e-1)" "unprognostic (6.62e-2)" "unprognostic (5.55e-3)" "unprognostic (1.35e-1)" "unprognostic (1.51e-2)" "unprognostic (5.71e-3)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" DPM3 "MGC125904, MGC125905, MGC34275" ENSG00000179085 "Dolichyl-phosphate mannosyltransferase subunit 3, regulatory" Q9P2X0 1 155139891-155140595 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014667 Approved NA NA 290000 "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA014667: AB_1847848" "unprognostic (6.47e-2)" "unprognostic (1.49e-2)" "unprognostic (1.18e-1)" "prognostic favorable (7.09e-5)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.67e-2)" "unprognostic (6.83e-3)" "unprognostic (4.71e-1)" "prognostic favorable (8.97e-5)" "unprognostic (1.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.75e-1)" "unprognostic (1.50e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "prognostic favorable (8.64e-4)" DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845780 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 10.4;brain: 21.0;pancreas: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 4395.9;Excitatory neurons: 2962.3;Inhibitory neurons: 3154.3;Oligodendrocyte precursor cells: 929.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lung cancer: 4.8;Rhabdoid: 10.6" "Adipose visceral - Mesothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "HPA048767: AB_2680515" "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153748133-154894285 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.0;endometrium 1: 56.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 651.3;Inhibitory neurons: 1147.6;Oligodendrocyte precursor cells: 1827.7" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 11.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA050509: AB_2681150" "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" DPY19L1 KIAA0877 ENSG00000173852 "Dpy-19 like C-mannosyltransferase 1" Q2PZI1 7 34927292-35038271 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.8;Early spermatids: 135.6;Excitatory neurons: 128.1;Late spermatids: 109.1;Oligodendrocytes: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059139 Uncertain Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 27: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA059139: AB_2683921" "unprognostic (4.66e-2)" "unprognostic (1.11e-3)" "unprognostic (8.53e-3)" "unprognostic (2.47e-3)" "unprognostic (2.50e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (3.57e-2)" "unprognostic (1.14e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.21e-1)" "unprognostic (1.88e-2)" "unprognostic (3.99e-1)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (4.12e-2)" DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 81.0" "Group enriched" "Detected in many" 4 "Early spermatids: 79.0;Excitatory neurons: 119.9;Inhibitory neurons: 131.7;Late spermatids: 136.2;Oligodendrocyte precursor cells: 116.5;Spermatocytes: 55.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 24: Non-specific - Transcription" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" DPY19L3 ENSG00000178904 "Dpy-19 like C-mannosyltransferase 3" Q6ZPD9 19 32405543-32485895 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 67.8;Oligodendrocyte precursor cells: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008325 Approved Approved Microtubules NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" Microtubules "HPA008325: AB_1847853" "unprognostic (9.58e-3)" "unprognostic (3.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.55e-4)" "unprognostic (2.00e-2)" "unprognostic (3.76e-2)" "unprognostic (1.28e-3)" "unprognostic (3.27e-1)" "prognostic favorable (1.70e-4)" "unprognostic (3.26e-1)" "unprognostic (1.02e-2)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024780 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 191.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 73: B-cells - B-cell function" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 25.9;retina: 8.2" "Group enriched" "Detected in some" 15 "Bipolar cells: 31.3;Horizontal cells: 42.2" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "basal ganglia: 46.6;cerebral cortex: 12.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.1;Bone cancer: 1.6" "Region enriched" "Detected in many" 9 "basal ganglia: 164.5" "Region enriched" "Detected in many" 13 "basal ganglia: 119.1" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 "Plasma membrane" Cytosol "HPA013393: AB_1847833, HPA017304: " "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409605-113475691 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 65.2;pituitary gland: 58.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.3;Horizontal cells: 15.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 163.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.6" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "basal ganglia: 205.4" "Region enriched" "Detected in many" 4 "basal ganglia: 192.0" "HPA015139, HPA015691" Supported Supported NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 "HPA015139: , HPA015691: AB_1847834" "unprognostic (8.49e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-4)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.40e-2)" "unprognostic (8.33e-4)" "unprognostic (1.10e-1)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (4.82e-2)" "unprognostic (8.49e-3)" DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 150.1;Cone photoreceptor cells: 171.6;dendritic cells: 41.2;Rod photoreceptor cells: 169.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Bipolar cells - Visual perception" 6 "Plasma membrane" Centrosome "HPA062682: " "unprognostic (8.83e-2)" "unprognostic (2.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.81e-2)" "unprognostic (7.52e-2)" "unprognostic (7.89e-3)" "unprognostic (3.14e-2)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (5.07e-2)" "unprognostic (3.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-4)" "unprognostic (1.26e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-1)" DRD5 "DRD1B, DRD1L2" ENSG00000169676 "Dopamine receptor D5" P21918 4 9781634-9784009 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Dystonia, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.6;lymphoid tissue: 1.3;stomach 1: 4.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.1;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 9.1" HPA048930 Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Neurons - Synaptic function" 1 "HPA048930: AB_2680562" "unprognostic (2.03e-2)" "unprognostic (2.63e-1)" "unprognostic (9.73e-2)" "unprognostic (4.27e-2)" "unprognostic (4.44e-3)" "unprognostic (1.98e-2)" "unprognostic (1.32e-4)" "unprognostic (5.09e-4)" "unprognostic (6.51e-2)" "unprognostic (1.46e-1)" "unprognostic (7.36e-3)" DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 222.8" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 27.4;Suprabasal keratinocytes: 78.4" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Cancer enriched" "Detected in single" 7 "ovarian cancer: 6.4" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075379 Enhanced NA NA 27000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 165.7;vagina: 94.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 467.2;Distal enterocytes: 308.6;Squamous epithelial cells: 821.6;Suprabasal keratinocytes: 1501.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 29.9;neutrophil: 8.4" "Lineage enriched" "Detected in many" 14 "granulocytes: 29.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 24000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Endoplasmic reticulum" "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 96.0;skin 1: 362.7" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 522.5;Basal squamous epithelial cells: 316.7;Squamous epithelial cells: 409.7;Suprabasal keratinocytes: 603.7" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 21.2;cervical cancer: 33.3;Esophageal cancer: 44.7;Gallbladder cancer: 15.6;head and neck cancer: 54.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "Low region specificity" "Detected in many" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 13: Skin - Cornification" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.1;pituitary gland: 4.0;retina: 1.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1045.7;Oligodendrocyte precursor cells: 4106.7" "Cancer enriched" "Detected in single" 14 "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "Golgi apparatus" "HPA019324: AB_2670118, HPA057493: " "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (9.98e-2)" "unprognostic (5.49e-4)" "unprognostic (1.78e-1)" "unprognostic (9.58e-2)" "unprognostic (7.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (2.12e-2)" "unprognostic (2.00e-3)" "unprognostic (2.17e-2)" "unprognostic (2.29e-1)" "unprognostic (8.75e-2)" "unprognostic (5.46e-3)" DSCAML1 KIAA1132 ENSG00000177103 "DS cell adhesion molecule like 1" Q8TD84 11 117427772-117817525 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;retina: 19.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 79.8;Excitatory neurons: 172.5;Inhibitory neurons: 222.7;Oligodendrocyte precursor cells: 331.1;Oligodendrocytes: 433.0;Rod photoreceptor cells: 160.2" "Cancer enhanced" "Detected in some" "glioma: 1.9;renal cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.2;Uterine cancer: 5.2" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035230 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "HPA035230: AB_2674527" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" "unprognostic (1.07e-2)" "unprognostic (6.27e-5)" "unprognostic (8.48e-2)" "unprognostic (1.56e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (7.96e-2)" "unprognostic (2.89e-2)" "unprognostic (2.39e-3)" "unprognostic (8.37e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-2)" DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 196.1;Late spermatids: 274.4;Macrophages: 135.2;Mesothelial cells: 126.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014764 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 81.8;Extravillous trophoblasts: 86.7;Oligodendrocyte precursor cells: 105.7;Oligodendrocytes: 96.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 549.7" "Group enriched" "Detected in some" 10 "Basal keratinocytes: 303.9;Suprabasal keratinocytes: 912.6" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;Esophageal cancer: 1.7;ovarian cancer: 3.3" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 13: Skin - Cornification" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 152.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 281.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 63.2" "Immune cell enriched" "Detected in single" 12 "basophil: 8.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 305.1;vagina: 115.5" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 371.0;Basal squamous epithelial cells: 565.8;Squamous epithelial cells: 1093.0;Suprabasal keratinocytes: 703.4" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cancer enhanced" "Detected in many" "Esophageal cancer: 39.7;Gallbladder cancer: 47.1;head and neck cancer: 72.0" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 46: Basophils - Proteolysis" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" DSG4 "CDHF13, LAH" ENSG00000175065 "Desmoglein 4" Q86SJ6 18 31376777-31414912 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 2.8" "Cell type enhanced" "Detected in single" "Early spermatids: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA059456, HPA079244" Enhanced NA NA 320000 "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA059456: AB_2684025, HPA079244: " "unprognostic (9.86e-2)" "unprognostic (8.61e-2)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "unprognostic (5.55e-2)" "unprognostic (5.61e-2)" "unprognostic (2.11e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "unprognostic (2.14e-1)" "unprognostic (1.79e-1)" DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493291-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 176.6;choroid plexus: 74.1;heart muscle: 144.4;skeletal muscle: 157.4;tongue: 203.2" "Cell type enhanced" "Detected in many" "Astrocytes: 1665.5;Excitatory neurons: 488.9;Inhibitory neurons: 626.0;Oligodendrocyte precursor cells: 461.3;Oligodendrocytes: 341.9" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.4;T-cells: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 4 "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 105.5;skin 1: 101.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 195.1;Alveolar cells type 2: 258.4;Glandular and luminal cells: 71.7;Suprabasal keratinocytes: 83.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Region enriched" "Detected in all" 5 "cerebellum: 77.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.3;head and neck cancer: 15.4" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 13.5" HPA023544 Approved NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 1 "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favorable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" DUOXA1 "FLJ32334, mol, NIP, NUMBIP" ENSG00000140254 "Dual oxidase maturation factor 1" Q1HG43 15 45117366-45129938 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 183.7;thyroid gland: 107.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.3;Alveolar cells type 2: 146.3;Glandular and luminal cells: 41.0;Squamous epithelial cells: 61.0;Suprabasal keratinocytes: 74.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder cancer: 8.0;cervical cancer: 9.9;Esophageal cancer: 9.7;head and neck cancer: 21.2" "Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041578 Approved NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "HPA041578: AB_10795691" "unprognostic (1.28e-1)" "unprognostic (1.32e-3)" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (2.71e-1)" "unprognostic (6.87e-3)" "unprognostic (1.03e-1)" "unprognostic (4.45e-2)" "unprognostic (6.69e-2)" "unprognostic (3.68e-2)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.17e-5)" "unprognostic (8.11e-2)" "unprognostic (1.12e-2)" "unprognostic (4.69e-2)" "unprognostic (5.36e-2)" DUOXA2 ENSG00000140274 "Dual oxidase maturation factor 2" Q1HG44 15 45114326-45118421 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" "Congenital hypothyroidism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 61.7;urinary bladder: 40.4" "Group enriched" "Detected in some" 7 "Ductal cells: 935.0;Exocrine glandular cells: 806.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 27.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA063548 Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "HPA063548: AB_2685037" "unprognostic (1.87e-1)" "unprognostic (9.88e-2)" "unprognostic (7.37e-2)" "unprognostic (6.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.00e-3)" "unprognostic (6.73e-2)" "unprognostic (2.03e-1)" "unprognostic (2.10e-1)" "unprognostic (3.15e-2)" "unprognostic (1.26e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-4)" "unprognostic (9.75e-2)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" "unprognostic (5.54e-2)" DUS4L-BCAP29 ENSG00000288558 "DUS4L-BCAP29 readthrough" 7 107563971-107623317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA029215, HPA044301, HPA049694" Approved Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 2: Skeletal myocytes - Muscle contraction" Cytosol "HPA029215: AB_10602331, HPA044301: AB_10967460, HPA049694: AB_2680854" DYM "DMC, FLJ20071, SMC" ENSG00000141627 Dymeclin Q7RTS9 18 49036387-49461347 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 450.4;Excitatory neurons: 167.3;Inhibitory neurons: 195.6;Late spermatids: 172.5;Oligodendrocytes: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043551, HPA049187" Approved Supported "Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Pancreas - Proteolysis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 18: Early spermatids - Unknown function" 2 "Golgi apparatus" "HPA043551: AB_2678547, HPA049187: AB_2680668" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.12e-3)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.85e-3)" "unprognostic (1.77e-1)" "unprognostic (1.72e-1)" "unprognostic (8.30e-3)" "unprognostic (2.53e-2)" "unprognostic (2.58e-2)" "prognostic favorable (2.76e-5)" "unprognostic (3.89e-1)" "unprognostic (1.69e-1)" "unprognostic (4.26e-3)" "prognostic unfavorable (5.26e-5)" DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 28.4" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 6.2;Serous glandular cells: 6.6;Suprabasal keratinocytes: 23.9" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 78.4;Intestinal goblet cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 29: Forebrain - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 7 Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: AB_2683271" "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453561-71686763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 51.6;skeletal muscle: 122.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 37.3;Excitatory neurons: 33.6;Lymphatic endothelial cells: 85.1;Oligodendrocytes: 58.4;Oocytes: 35.3;Skeletal myocytes: 38.1;Syncytiotrophoblasts: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 51.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 51.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 16 "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 143.8;Cone photoreceptor cells: 316.0;Excitatory neurons: 140.3;Spermatocytes: 344.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 24: Non-specific - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 42: Ciliated cells - Cilium assembly" 24 Vesicles "HPA035066: AB_10601549, HPA049232: AB_2680684" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favorable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "B-cells: 18.6;Plasma cells: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.5;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.5" "Cancer enhanced" "Detected in all" "lymphoma: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 71: Thymus - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 2 Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 318.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 242.4;Hepatocytes: 634.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Hepatocytes - Metabolism" 159 "Nuclear membrane, Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 299.6;Suprabasal keratinocytes: 271.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 160.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 5 "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 83.5;ovary: 96.6;pituitary gland: 26.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.1;Muller glia cells: 92.0;Ovarian stromal cells: 9.7;Peritubular cells: 20.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enhanced" "Detected in all" "hypothalamus: 235.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 13.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Uncertain "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 25: Bipolar cells - Visual perception" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 17 "Adipocytes: 239.5;Endothelial cells: 292.0;Lymphatic endothelial cells: 562.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.8;pancreatic cancer: 11.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 80.5;Oligodendrocyte precursor cells: 28.3;Oligodendrocytes: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.1" "Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" "Developmental protein" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 20 Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" EDA2R "EDA-A2R, EDAA2R, TNFRSF27, XEDAR" ENSG00000131080 "Ectodysplasin A2 receptor" Q9HAV5 X 66595637-66639298 "Predicted membrane proteins" Differentiation "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 18.3;testis cancer: 23.3" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" HPA054522 Approved "Cell Junctions" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 10 "Cell Junctions" "HPA054522: AB_2682516" "unprognostic (1.31e-3)" "unprognostic (3.17e-3)" "unprognostic (2.19e-1)" "unprognostic (8.49e-3)" "unprognostic (4.15e-3)" "unprognostic (3.63e-3)" "unprognostic (2.48e-2)" "unprognostic (3.37e-2)" "unprognostic (2.82e-1)" "unprognostic (7.17e-2)" "unprognostic (6.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (8.23e-2)" "unprognostic (4.92e-2)" "unprognostic (3.08e-1)" EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.7;Squamous epithelial cells: 5.3;T-cells: 1.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 76 "T-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.6;Gastric cancer: 9.2;pancreatic cancer: 7.2" "Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042292 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 7: T-cells - T-cell receptor" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 110.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 116.1;Leydig cells: 43.2;Ovarian stromal cells: 51.5;Peritubular cells: 66.9;Smooth muscle cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 48: Smooth muscle cells - Signal transduction" 2 "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 123.5" "Cell type enhanced" "Detected in many" "Adipocytes: 108.5;Astrocytes: 119.8;Endothelial cells: 74.1;Leydig cells: 82.0;Lymphatic endothelial cells: 93.3;Melanocytes: 173.5;Muller glia cells: 102.3;Sertoli cells: 103.3;Smooth muscle cells: 78.6" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "Myeloma: 84.2;skin cancer: 130.7" "Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" EDRF1 "C10orf137, DKFZp586F1019, FLJ21617" ENSG00000107938 "Erythroid differentiation regulatory factor 1" Q3B7T1 10 125719515-125764143 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.1;Late spermatids: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031820 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" 6 Nucleoplasm "Centrosome, Cytosol" "HPA031820: AB_10600753" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.64e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-2)" "unprognostic (8.84e-4)" "unprognostic (4.76e-3)" "unprognostic (8.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.63e-3)" "unprognostic (4.62e-2)" "prognostic unfavorable (3.16e-5)" "unprognostic (3.44e-3)" "unprognostic (5.51e-2)" "unprognostic (1.38e-1)" "unprognostic (7.68e-3)" EEF1AKMT4-ECE2 ENSG00000284917 "EEF1AKMT4-ECE2 readthrough" P0DPD8 3 184249695-184293031 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Methyltransferase, Multifunctional enzyme, Protease, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062215 Uncertain Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA062215: AB_2684714" EEF1E1 "AIMP3, P18" ENSG00000124802 "Eukaryotic translation elongation factor 1 epsilon 1" O43324 6 8073360-8102559 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 247.2;Oocytes: 189.7;Proximal tubular cells: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027901, HPA057866" Approved Supported Nucleoplasm,Cytosol NA NA 18000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Testis - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 11: Late spermatids - Unknown function" 2 "Nucleoplasm, Cytosol" "HPA027901: AB_10611960, HPA057866: AB_2683547" "unprognostic (9.39e-3)" "prognostic favorable (3.16e-4)" "unprognostic (2.23e-1)" "unprognostic (2.36e-2)" "unprognostic (1.42e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.55e-7)" "unprognostic (1.79e-1)" "unprognostic (5.67e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.13e-1)" "unprognostic (1.76e-2)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" EFCAB14 KIAA0494 ENSG00000159658 "EF-hand calcium binding domain 14" O75071 1 46674659-46719146 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 154.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011224, HPA011938" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA 110000 "Cluster 1: T-cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" Cytosol "Nucleoli, Golgi apparatus" "HPA011224: AB_1852314, HPA011938: AB_1852317" "unprognostic (2.44e-1)" "unprognostic (5.90e-2)" "unprognostic (7.53e-2)" "unprognostic (2.36e-1)" "unprognostic (7.34e-2)" "unprognostic (4.55e-2)" "unprognostic (1.39e-2)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (3.00e-1)" "unprognostic (1.13e-3)" "unprognostic (1.00e-2)" "unprognostic (5.77e-2)" "unprognostic (1.94e-1)" "unprognostic (2.46e-1)" EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.0;skin 1: 99.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.9;Basal squamous epithelial cells: 34.3;Extravillous trophoblasts: 34.2;Oocytes: 65.4;Squamous epithelial cells: 30.9;Suprabasal keratinocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "CAB010494: AB_2097783" "unprognostic (3.75e-2)" "unprognostic (1.53e-2)" "unprognostic (1.56e-2)" "unprognostic (1.51e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.86e-2)" "unprognostic (3.56e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.66e-10)" "unprognostic (2.83e-3)" "unprognostic (6.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 29.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 276.2;Excitatory neurons: 771.5;Inhibitory neurons: 358.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 15: NK-cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 28 "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Basal keratinocytes: 96.4;Basal squamous epithelial cells: 88.9;Extravillous trophoblasts: 86.9;Suprabasal keratinocytes: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 218.0;Endothelial cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 7.5;Excitatory neurons: 8.8;Mesothelial cells: 16.7" "Cancer enhanced" "Detected in many" "glioma: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 11000 "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 1 "HPA001623: AB_1848026" "unprognostic (5.17e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (3.27e-1)" "unprognostic (1.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.21e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.00e-1)" "unprognostic (8.56e-2)" "unprognostic (2.20e-2)" EGFR "ERBB, ERBB1, ERRP" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 278.2;Salivary duct cells: 235.0;Syncytiotrophoblasts: 428.1" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534, CAB080313, CAB080314" Enhanced Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cell Junctions" "Secreted to blood" Receptor NA NA 4740000 88000000 "Cluster 58: Placenta - Pregnancy" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Fibroblasts - ECM organization" 270 "Plasma membrane, Cell Junctions" "Nucleoplasm, Nucleoli" "CAB000035: , CAB068186: AB_2665679, CAB073534: , CAB080313: , CAB080314: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 447.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 526.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 8 "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88691518 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.3" "Cell type enhanced" "Detected in many" "Plasma cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 30.7" "Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 1 "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 33: Non-specific - ATP binding" "Cluster 18: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 26 Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" EIF3L "EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025" ENSG00000100129 "Eukaryotic translation initiation factor 3 subunit L" Q9Y262 22 37848868-37889407 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003028 Approved Approved Nucleoplasm,Nucleoli NA NA 72000 "Cluster 13: Non-specific - Mitochondria" "Cluster 18: Non-specific - Ribosome" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 9 Nucleoli Nucleoplasm "HPA003028: AB_1078726" "unprognostic (2.07e-2)" "unprognostic (3.02e-2)" "unprognostic (5.06e-3)" "unprognostic (3.20e-1)" "unprognostic (3.79e-3)" "unprognostic (9.86e-2)" "unprognostic (1.35e-1)" "unprognostic (9.65e-2)" "unprognostic (2.66e-1)" "unprognostic (5.81e-3)" "unprognostic (2.35e-1)" "unprognostic (9.74e-2)" "prognostic favorable (6.11e-4)" "unprognostic (1.48e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (2.03e-3)" ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 151.7;salivary gland: 161.2;stomach 1: 85.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 127.2;Intestinal goblet cells: 163.4;Prostatic glandular cells: 355.4;Serous glandular cells: 259.7;Undifferentiated cells: 105.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.7" "Cancer enhanced" "Detected in many" "breast cancer: 34.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" ELAPOR2 "EIG121L, FLJ31340, KIAA1324L" ENSG00000164659 "Endosome-lysosome associated apoptosis and autophagy regulator family member 2" A8MWY0 7 86876906-87059654 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 21.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 73.1;Early spermatids: 94.5;Excitatory neurons: 55.4;Inhibitory neurons: 104.5;Late spermatids: 97.3;Oligodendrocytes: 358.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.3;T-cells: 2.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044527, HPA076093" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 65: Neurons - Synaptic function" "Endoplasmic reticulum" "HPA044527: AB_10963793, HPA076093: AB_2686776" "unprognostic (2.78e-2)" "unprognostic (9.37e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-4)" "unprognostic (3.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "unprognostic (2.28e-2)" "unprognostic (6.82e-2)" "unprognostic (8.82e-3)" "unprognostic (3.86e-3)" "unprognostic (1.25e-1)" "unprognostic (4.32e-1)" "unprognostic (1.37e-1)" ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1665745-1747946 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 17.0;Endothelial cells: 5.7;Hepatocytes: 10.6;Inhibitory neurons: 18.3;Rod photoreceptor cells: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.4;Sarcoma: 14.1" "Colon - Endothelial cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 43000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" "Nucleoplasm, Cell Junctions" "HPA066382: AB_2732744" "unprognostic (8.45e-2)" "unprognostic (3.39e-3)" "unprognostic (6.54e-4)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.68e-4)" "unprognostic (4.60e-3)" "unprognostic (1.63e-3)" "unprognostic (6.60e-2)" "unprognostic (4.14e-3)" "unprognostic (1.11e-2)" "unprognostic (2.31e-2)" "unprognostic (7.47e-3)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-1)" ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 13.8;retina: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.3;Excitatory neurons: 11.2;Horizontal cells: 12.0;Inhibitory neurons: 15.5;Oligodendrocyte precursor cells: 34.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.8" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000781: AB_1079280" "unprognostic (2.74e-1)" "unprognostic (6.81e-2)" "unprognostic (2.80e-2)" "unprognostic (1.31e-5)" "unprognostic (3.28e-1)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "unprognostic (4.25e-2)" "unprognostic (6.05e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (4.51e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 53.2;pituitary gland: 21.1;retina: 31.6;skin 1: 28.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 27.4;Excitatory neurons: 122.0;Horizontal cells: 30.2;Inhibitory neurons: 99.5;Oligodendrocyte precursor cells: 75.9" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 26.2" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038434, HPA038435" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA038434: AB_10794324, HPA038435: AB_10795575" "unprognostic (2.74e-1)" "unprognostic (1.72e-4)" "unprognostic (2.58e-2)" "unprognostic (9.13e-2)" "unprognostic (3.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-1)" "unprognostic (6.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (6.29e-2)" "unprognostic (9.44e-2)" "unprognostic (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 344.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 59: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 29.6" "Cell type enhanced" "Detected in some" "Adipocytes: 2.6;Breast myoepithelial cells: 3.4;Oocytes: 12.5;Spermatogonia: 4.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 82: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Non-specific - Transcription" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 301.8;Prostatic glandular cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 3: Basal prostatic cells - Lipid metabolism" 13 "Endoplasmic reticulum" "CAB017042: , HPA047752: AB_2680147, HPA054197: AB_2682413" "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (2.76e-2)" ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.6;Hepatocytes: 89.8;Inhibitory neurons: 75.2;Oligodendrocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 2.4;MAIT T-cell: 2.6;memory CD4 T-cell: 1.0;memory CD8 T-cell: 1.3;naive CD8 T-cell: 1.0;NK-cell: 3.3" "Group enriched" "Detected in many" 21 "NK-cells: 3.3;T-cells: 2.6" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Hepatocytes - Metabolism" 3 "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favorable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Microglial cells: 181.6;Oligodendrocytes: 84.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" 11 "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" ELP6 "C3orf75, FLJ20211, TMEM103" ENSG00000163832 "Elongator acetyltransferase complex subunit 6" Q0PNE2 3 47495640-47513712 "Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046358, HPA064545" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Centrosome "HPA046358: AB_10961011, HPA064545: AB_2685282" "unprognostic (2.00e-3)" "unprognostic (2.27e-1)" "unprognostic (7.41e-3)" "unprognostic (2.41e-2)" "unprognostic (2.67e-1)" "unprognostic (8.62e-2)" "unprognostic (4.24e-3)" "unprognostic (1.66e-1)" "unprognostic (2.11e-2)" "unprognostic (1.24e-2)" "unprognostic (2.07e-2)" "unprognostic (5.38e-2)" "prognostic favorable (3.42e-6)" "unprognostic (1.54e-1)" "unprognostic (9.05e-2)" "unprognostic (2.30e-1)" "unprognostic (6.29e-2)" EMC1 KIAA0090 ENSG00000127463 "ER membrane protein complex subunit 1" Q8N766 1 19215660-19251552 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048904 Approved NA NA 14000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA048904: AB_2680552" "unprognostic (9.46e-3)" "unprognostic (1.91e-3)" "unprognostic (1.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-3)" "prognostic unfavorable (8.56e-6)" "unprognostic (5.98e-2)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (4.96e-2)" "unprognostic (2.50e-1)" "unprognostic (3.02e-2)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.43e-4)" EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.8" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" "Developmental protein" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 2: Skeletal myocytes - Muscle contraction" 8 "HPA053905: AB_2682303, HPA062723: " "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (9.86e-3)" "unprognostic (1.65e-1)" "unprognostic (6.94e-2)" "unprognostic (8.38e-3)" "unprognostic (3.23e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "prognostic favorable (4.39e-4)" "unprognostic (5.01e-2)" "prognostic favorable (6.64e-6)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" EMC3 TMEM111 ENSG00000125037 "ER membrane protein complex subunit 3" Q9P0I2 3 9962682-10011202 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042372 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 57: Platelets - Hemostasis" 3 "HPA042372: AB_10795609" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.59e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-3)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.81e-6)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.71e-2)" "unprognostic (5.58e-2)" EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 1 "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" EMC6 "MGC2963, RAB5IFL, TMEM93" ENSG00000127774 "ER membrane protein complex subunit 6" Q9BV81 17 3668812-3669668 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062681 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 16 Centrosome Nucleoplasm "HPA062681: AB_2684831" "unprognostic (2.21e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (7.58e-3)" "unprognostic (4.17e-2)" "unprognostic (1.94e-1)" "unprognostic (6.37e-2)" "unprognostic (3.27e-1)" "unprognostic (6.32e-2)" EMC7 "C11orf3, C15orf24" ENSG00000134153 "ER membrane protein complex subunit 7" Q9NPA0 15 34084017-34101862 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010029 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 6 "HPA010029: AB_1078335" "unprognostic (2.16e-1)" "unprognostic (8.16e-3)" "unprognostic (5.28e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.75e-2)" "prognostic unfavorable (9.25e-5)" "unprognostic (1.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-3)" "unprognostic (4.67e-2)" "unprognostic (3.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.31e-1)" "unprognostic (2.58e-1)" "unprognostic (2.49e-2)" "unprognostic (2.47e-3)" EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 394.2;Endothelial cells: 263.1;Lymphatic endothelial cells: 174.4;Microglial cells: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" "No annotated function" NA NA 470000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" EMD "LEMD5, STA" ENSG00000102119 Emerin P50402 X 154379273-154381574 "Disease related genes, Human disease related genes, Predicted membrane proteins" Actin-binding "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000609, CAB001545, CAB002029, CAB058694, CAB062552" Supported Enhanced "Nuclear membrane,Endoplasmic reticulum" NA NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 72 "Nuclear membrane" "Endoplasmic reticulum" "CAB001545: AB_2100047, CAB002029: AB_442088, CAB058694: AB_2665587, CAB062552: AB_2665586, HPA000609: AB_1078736" "unprognostic (2.92e-1)" "unprognostic (6.59e-3)" "unprognostic (4.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.16e-1)" "unprognostic (9.12e-3)" "unprognostic (3.58e-2)" "unprognostic (6.06e-3)" "unprognostic (7.74e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-2)" "unprognostic (1.49e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (7.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.99e-1)" EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2191.8;vagina: 794.5" "Cell type enhanced" "Detected in many" "Adipocytes: 800.2;Basal keratinocytes: 628.4;Endothelial cells: 556.8;Lymphatic endothelial cells: 1185.5;Squamous epithelial cells: 923.7;Suprabasal keratinocytes: 1142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.5" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.5" "Cancer enhanced" "Detected in all" "Rhabdoid: 589.7" "Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 5.9;spinal cord: 21.0" HPA046912 Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 55 Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 223.6" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 3419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other), Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 790.0;Hofbauer cells: 885.6;Langerhans cells: 2197.3;Macrophages: 757.3;Melanocytes: 1243.7;monocytes: 1528.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 45 "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" ENDOD1 KIAA0830 ENSG00000149218 "Endonuclease domain containing 1" O94919 11 95089846-95132645 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 92.9;Oligodendrocytes: 114.4;Schwann cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008932, HPA010517" Enhanced Approved "Nuclear membrane" "Secreted - unknown location" Immunity NA NA 5200000 "Cluster 14: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Nuclear membrane" "HPA008932: AB_2262252, HPA010517: AB_1852351" "unprognostic (8.81e-3)" "unprognostic (1.92e-2)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (2.84e-1)" "prognostic favorable (6.64e-7)" "unprognostic (5.92e-2)" "unprognostic (2.35e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (3.27e-4)" ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 511.3" "Group enriched" "Detected in many" 4 "Adipocytes: 404.5;Endothelial cells: 476.2;Extravillous trophoblasts: 342.8;Leydig cells: 473.5;Peritubular cells: 1364.0;Syncytiotrophoblasts: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 159.0;kidney: 86.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 598.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.3;Kidney cancer: 14.1" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 102.2;Endometrial stromal cells: 78.6;Hepatocytes: 95.2;Peritubular cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 2 "CAB032904: AB_2099635, HPA062066: AB_2684674" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 1296.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 969.5" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 54.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 54.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.1" "Breast - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" Enzyme NA NA 1200000000 "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129989-46146688 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 95.2;dendritic cells: 70.1;Oligodendrocytes: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 2 "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favorable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 237.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.1;Muller glia cells: 78.5;Prostatic glandular cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 620000 "Cluster 1: T-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" ENSG00000197991 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Early spermatids: 3.1;Late spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 18: Early spermatids - Unknown function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" ENSG00000198211 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.9" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 44: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB011512: AB_444319, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.90e-4)" "unprognostic (6.87e-2)" ENSG00000241690 ENSG00000241690 "Novel protein" 20 2814968-2818066 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 35 "testis: 13.5" "Cell type enriched" "Detected in single" 7 "Late spermatids: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077873 Approved "Vesicles,Plasma membrane" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" Vesicles "HPA077873: " ENSG00000249624 ENSG00000249624 "Novel protein" 21 33229892-33297160 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Myeloma: 2.3" HPA047550 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" "HPA047550: AB_2680086" "unprognostic (2.39e-1)" "unprognostic (8.87e-2)" "unprognostic (4.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.62e-1)" "unprognostic (3.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.12e-1)" "unprognostic (5.46e-2)" "unprognostic (2.92e-2)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (1.53e-2)" "unprognostic (2.33e-2)" ENSG00000250264 ENSG00000250264 "Novel protein, TAP2-HLA-DOB readthrough" 6 32813767-32838822 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.0;Gastric mucus-secreting cells: 2.4;Squamous epithelial cells: 1.4;T-cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA001312 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" "Nuclear speckles, Endoplasmic reticulum" "HPA001312: AB_1080206" "unprognostic (6.13e-2)" "unprognostic (8.76e-3)" "unprognostic (4.62e-1)" "unprognostic (9.88e-2)" "unprognostic (1.99e-1)" "unprognostic (3.39e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.49e-1)" "unprognostic (8.73e-2)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" ENSG00000250349 ENSG00000250349 "Novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein" X 37349330-38687674 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skeletal muscle: 4.5" "Cell type enhanced" "Detected in single" "Lymphatic endothelial cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003140 Uncertain NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 49: Non-specific - Transcription" "HPA003140: AB_1078454" ENSG00000250424 ENSG00000250424 "Novel protein, MINDY4 and AQP1 readthrough" 7 30852273-30923812 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019206, HPA030130" Approved Approved "Plasma membrane" NA NA "Cluster 70: DU4475 - Unknown function" "Plasma membrane" "HPA019206: AB_1844965, HPA030130: AB_10601565" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" "unprognostic (2.72e-4)" "unprognostic (5.13e-2)" "unprognostic (3.44e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-2)" "unprognostic (3.76e-1)" "unprognostic (2.49e-1)" "unprognostic (3.71e-2)" ENSG00000250644 ENSG00000250644 "Novel protein" 11 1734821-1763954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adrenal gland: 196.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.0;granulocytes: 5.6;Macrophages: 4.0;Salivary duct cells: 3.2;Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 71.5" HPA003001 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" "HPA003001: AB_1078404" "unprognostic (5.71e-2)" "unprognostic (1.79e-1)" "unprognostic (1.91e-6)" "unprognostic (1.77e-2)" "unprognostic (5.21e-2)" "unprognostic (6.20e-2)" "unprognostic (4.05e-3)" "unprognostic (1.45e-2)" "unprognostic (3.04e-1)" "unprognostic (1.14e-1)" "unprognostic (2.45e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-3)" "unprognostic (8.30e-4)" "unprognostic (7.35e-2)" "unprognostic (5.79e-5)" "unprognostic (7.47e-2)" ENSG00000251357 ENSG00000251357 "Novel protein" 22 23862188-23895223 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042960 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "HPA042960: AB_2678241" ENSG00000254692 ENSG00000254692 "Novel protein" 14 24189157-24213473 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA059249 Approved Approved "Golgi apparatus" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: T-cells - T-cell receptor" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.45e-2)" ENSG00000254979 ENSG00000254979 "Novel protein" 11 57387365-57424059 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.1;liver: 7.0;placenta: 6.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "melanoma: 0.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "basophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Cancer enriched" "Detected in some" 5 "Leukemia: 13.0" HPA038515 Supported NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: HMC-1 - Innate immune response" "HPA038515: AB_10675800" "unprognostic (1.12e-1)" "unprognostic (1.19e-1)" "unprognostic (5.10e-2)" "unprognostic (1.55e-4)" "unprognostic (2.16e-1)" "unprognostic (4.01e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-2)" "unprognostic (2.20e-1)" "unprognostic (3.08e-2)" "unprognostic (1.33e-2)" "unprognostic (1.79e-1)" "unprognostic (1.51e-10)" "unprognostic (4.86e-2)" "unprognostic (1.54e-1)" "unprognostic (5.59e-2)" "unprognostic (3.10e-1)" ENSG00000255641 ENSG00000255641 "Novel protein" 12 10412312-10436001 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 1.6;brain: 6.5;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in some" "NK-cells: 3.2;T-cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 135.0" "Lineage enriched" "Detected in many" 6 "NK-cells: 135.0" "Cancer enhanced" "Detected in some" "testis cancer: 3.0;thyroid cancer: 3.7" HPA062570 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA062570: AB_2684795" "unprognostic (6.09e-2)" ENSG00000258529 ENSG00000258529 "Novel protein" 11 111786286-111879425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" HPA038575 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 21: Testis - Unknown function" "Cluster 24: Non-specific - Unknown function" "Cluster 74: Neutrophils - Degranulation" "Endoplasmic reticulum" "HPA038575: AB_10672718" ENSG00000260272 ENSG00000260272 "Novel protein" 16 2496032-2520218 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.0;kidney: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044712 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Ciliated cells - Ion channel activity" "HPA044712: AB_10795619" "unprognostic (4.12e-1)" "unprognostic (9.64e-2)" "unprognostic (4.36e-3)" "unprognostic (1.13e-1)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (3.34e-2)" "unprognostic (2.34e-1)" "unprognostic (1.37e-1)" "unprognostic (9.77e-3)" "unprognostic (9.13e-2)" "unprognostic (9.83e-2)" "unprognostic (5.98e-3)" ENSG00000260342 ENSG00000260342 "Novel protein" 16 18788063-18801519 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 14.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (1.03e-2)" "unprognostic (8.89e-3)" "unprognostic (1.22e-1)" "unprognostic (3.59e-3)" "unprognostic (2.28e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-3)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.46e-1)" "unprognostic (1.40e-2)" "unprognostic (3.27e-1)" "unprognostic (3.18e-4)" "unprognostic (2.92e-1)" "unprognostic (3.89e-2)" "unprognostic (2.65e-2)" "unprognostic (3.95e-2)" ENSG00000260643 ENSG00000260643 "Novel protein" 16 81053587-81096296 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.6;Early spermatids: 9.1;Late spermatids: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA041368 Approved Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA041368: AB_10804001" "unprognostic (3.87e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-2)" "unprognostic (8.06e-2)" "unprognostic (1.08e-1)" "unprognostic (3.95e-2)" "unprognostic (8.11e-2)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (3.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.69e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.56e-3)" "unprognostic (3.03e-1)" ENSG00000261717 ENSG00000261717 "Novel TMEM170A-CFDP1 readthrough protein" 16 75412684-75464706 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skeletal muscle: 2.1" "Group enriched" "Detected in some" 10 "B-cells: 3.7;Basal squamous epithelial cells: 3.5;Erythroid cells: 1.5;Gastric mucus-secreting cells: 3.5;Macrophages: 2.0;Plasma cells: 6.0;Squamous epithelial cells: 3.5;T-cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA041316 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 49: Non-specific - Transcription" "HPA041316: AB_10794371" "unprognostic (1.57e-1)" ENSG00000261832 ENSG00000261832 "Novel protein" 16 28456371-28492098 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Early spermatids: 8.1;Late spermatids: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053611 Uncertain Approved Nucleoplasm NA NA "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.93e-3)" "unprognostic (8.88e-3)" "unprognostic (4.33e-3)" "unprognostic (2.66e-1)" "unprognostic (3.59e-1)" "unprognostic (9.85e-2)" "unprognostic (3.82e-4)" "unprognostic (3.25e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (6.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (3.74e-1)" ENSG00000265118 ENSG00000265118 "Novel protein" 17 31305213-31318831 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 221.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 2.0;lymphoma: 2.0;Myeloma: 3.1" HPA045033 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" "Golgi apparatus, Plasma membrane" "HPA045033: AB_2679191" "unprognostic (5.33e-2)" "unprognostic (3.44e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (5.88e-2)" "unprognostic (2.94e-2)" "unprognostic (2.40e-2)" "unprognostic (4.63e-2)" "unprognostic (3.23e-1)" "unprognostic (5.45e-5)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (4.53e-2)" ENSG00000267001 ENSG00000267001 "Novel protein" 19 2717769-2740048 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.3" "Group enriched" "Detected in some" 4 "B-cells: 3.2;Basal squamous epithelial cells: 3.3;Erythroid cells: 8.6;Gastric mucus-secreting cells: 4.1;Plasma cells: 5.0;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA058526 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "HPA058526: AB_2683743" ENSG00000267740 ENSG00000267740 "Novel protein" 19 5866171-5903787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.3;Cardiomyocytes: 2.1;Erythroid cells: 1.1;Plasma cells: 3.1;Squamous epithelial cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA072209 Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.12e-2)" "unprognostic (2.24e-1)" "unprognostic (3.38e-1)" ENSG00000269035 ENSG00000269035 "Novel protein" 19 17436611-17460804 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041580 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA041580: AB_10795700" ENSG00000274792 ENSG00000274792 Unmapped 386278-387620 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Uncertain Centrosome NA NA Centrosome "HPA057442: AB_2683442" ENSG00000275249 ENSG00000275249 Unmapped 372322-373405 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 11: Late spermatids - Unknown function" "HPA058889: AB_2683845" ENSG00000283761 ENSG00000283761 "Novel protein" 1 99970011-100083321 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.0" HPA073681 Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 40: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" Vesicles "HPA073681: AB_2686625" ENSG00000283765 ENSG00000283765 "Novel protein" 3 183815568-183884889 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;skeletal muscle: 5.3" "Group enriched" "Detected in some" 37 "Astrocytes: 17.0;Excitatory neurons: 22.6;Inhibitory neurons: 23.1;Microglial cells: 32.2;Oligodendrocyte precursor cells: 16.0;Oligodendrocytes: 26.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA019545 Uncertain Approved Mitochondria NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Neurons - Neuronal signaling" Mitochondria "HPA019545: AB_1855796" ENSG00000284776 ENSG00000284776 "Novel protein" 20 18567453-18744216 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Nucleoli, Cytosol" "HPA040981: AB_10673268" ENSG00000285526 ENSG00000285526 "Novel protein" 19 35106510-35124297 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;salivary gland: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.4" HPA010856 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" ENSG00000285880 ENSG00000285880 "ADRB3-GOT1L1 readthrough" 8 37934340-37965953 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 4.1;Enteroendocrine cells: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "HPA061969: AB_2732674" ENSG00000285947 ENSG00000285947 "Novel protein" 17 63917203-63931385 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 14.1;naive B-cell: 18.4" "Lineage enriched" "Detected in many" 5 "B-cells: 18.4" "Not detected" "Not detected" "HPA009178, HPA043715" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA009178: AB_1078483, HPA043715: AB_2678632" ENSG00000285982 ENSG00000285982 "Novel protein" 8 103398658-103501895 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA024763 Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" Mitochondria Nucleoplasm "HPA024763: " ENSG00000286235 ENSG00000286235 "Novel protein" 20 5950949-6039856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "HPA045141, HPA066433" Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Kidney cancer - Membrane components" Nucleoplasm Cytosol "HPA045141: AB_2679230, HPA066433: " ENSG00000286268 ENSG00000286268 "Novel protein" X 48521806-48545469 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.4;Erythroid cells: 2.2;Gastric mucus-secreting cells: 1.8;Plasma cells: 2.2;Squamous epithelial cells: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003130 Uncertain Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" "Nuclear membrane, Endoplasmic reticulum" "HPA003130: AB_1078717" ENSG00000289258 ENSG00000289258 "Novel protein" 10 86654518-86700020 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039147, HPA048955" Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 33: Neurons - Mixed function" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA039147: AB_10673304, HPA048955: AB_2680568" ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95877266 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.3;Endothelial cells: 64.1;Kupffer cells: 69.0;Langerhans cells: 143.9;Macrophages: 61.0;Microglial cells: 207.6;Plasma cells: 79.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 102.4" "Group enriched" "Detected in all" 4 "dendritic cells: 31.9;granulocytes: 102.4;monocytes: 41.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002494, HPA014067, CAB079986" Enhanced Uncertain Microtubules NA NA 19000 "Cluster 7: Non-specific - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Microtubules "CAB002494: AB_563557, CAB079986: , HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favorable (7.89e-4)" "unprognostic (5.09e-2)" ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048107-137054061 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 197.4;Peritubular cells: 91.6;Proximal enterocytes: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.3" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA017676: AB_1848179" "unprognostic (1.64e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (2.15e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.71e-2)" "unprognostic (4.97e-2)" "unprognostic (3.23e-1)" "unprognostic (2.99e-1)" "unprognostic (1.89e-1)" "prognostic favorable (3.51e-6)" "prognostic favorable (1.38e-4)" "unprognostic (2.51e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-3)" ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 55: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 41000 "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" ENTPD7 "FLJ30978, LALP1" ENSG00000198018 "Ectonucleoside triphosphate diphosphohydrolase 7" Q9NQZ7 10 99659509-99711241 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.2" "Cell type enriched" "Detected in many" 6 "dendritic cells: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014351 Uncertain Approved Nucleoplasm NA NA 65000 "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA014351: AB_1848183" "unprognostic (1.82e-1)" "unprognostic (7.26e-2)" "unprognostic (1.11e-2)" "unprognostic (6.01e-3)" "unprognostic (6.22e-2)" "unprognostic (3.32e-3)" "unprognostic (9.35e-2)" "unprognostic (3.77e-3)" "unprognostic (3.83e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "unprognostic (1.22e-1)" "unprognostic (2.99e-2)" "unprognostic (3.39e-1)" ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.9;liver: 14.1;stomach 1: 8.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 116.9;Intestinal goblet cells: 222.4;Paneth cells: 59.7;Proximal enterocytes: 148.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Colon - Colon enterocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" ENTREP1 "C9orf61, ENTREP, FAM189A2, X123" ENSG00000135063 "Endosomal transmembrane epsin interactor 1" Q15884 9 69324567-69392558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.2;thyroid gland: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 243.1;Lymphatic endothelial cells: 70.7;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029411, HPA057207" Approved NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 7 "HPA029411: AB_10602338, HPA057207: AB_2683369" "unprognostic (2.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.16e-6)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" "unprognostic (3.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.09e-1)" "unprognostic (2.71e-3)" "unprognostic (7.84e-2)" "unprognostic (1.07e-2)" "prognostic favorable (1.75e-5)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (4.82e-2)" "unprognostic (1.14e-1)" ENTREP2 "FAM189A1, KIAA0574, TMEM228" ENSG00000104059 "Endosomal transmembrane epsin interactor 2" O60320 15 29120252-29570979 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 24.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 196.0;Inhibitory neurons: 190.0;Oligodendrocyte precursor cells: 56.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.1" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009410, HPA010637" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm "HPA009410: AB_1852332, HPA010637: AB_1852333" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (5.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.71e-2)" "unprognostic (4.85e-3)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (3.39e-1)" "unprognostic (7.97e-2)" "unprognostic (5.00e-1)" "unprognostic (6.70e-3)" "unprognostic (2.39e-2)" "unprognostic (9.03e-2)" "unprognostic (2.50e-2)" "unprognostic (3.12e-1)" ENTREP3 "C1orf2, cote1, FAM189B" ENSG00000160767 "Endosomal transmembrane epsin interactor 3" P81408 1 155247205-155255483 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006659, HPA050674" Uncertain Supported Nucleoplasm NA NA "Cluster 66: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Nucleoplasm "HPA006659: AB_1078339, HPA050674: AB_2681213" "unprognostic (1.56e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.59e-5)" "unprognostic (1.46e-2)" "unprognostic (4.86e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.70e-2)" "unprognostic (3.49e-2)" "unprognostic (2.73e-1)" "unprognostic (5.15e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.43e-7)" "unprognostic (4.16e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-3)" "unprognostic (3.25e-2)" EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 239.7;Cone photoreceptor cells: 226.0;Rod photoreceptor cells: 363.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 92.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 142.2" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 55: Non-specific - Transcription" 1 "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 342.8" "Cell type enhanced" "Detected in many" "Late spermatids: 344.6;Microglial cells: 414.2;Muller glia cells: 391.4;Rod photoreceptor cells: 1208.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Retina - Visual perception" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 66: Photoreceptor cells - Visual perception" 2 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 296.8;Inhibitory neurons: 228.0;Late spermatids: 302.0;monocytes: 188.0;Syncytiotrophoblasts: 252.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.5" "Lineage enriched" "Detected in many" 5 "monocytes: 12.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 34: Neurons - Neuronal signaling" 5 "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" EPCAM "17-1A, 323/A3, Ber-Ep4, BerEp4, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC-31, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 780.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2590.4;Intestinal goblet cells: 1370.3;Paneth cells: 2221.3;Proximal enterocytes: 2597.5;Undifferentiated cells: 1520.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 762.9" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 5 "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 47.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 13.2;Basal squamous epithelial cells: 12.9;Mesothelial cells: 22.1;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 35.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" "Growth factor" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 55.6;parathyroid gland: 199.7" "Cell type enhanced" "Detected in many" "Early spermatids: 24.5;Squamous epithelial cells: 33.0;Suprabasal keratinocytes: 33.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "choroid plexus: 2.6" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" CAB026144 Uncertain NA NA 32000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;intestine: 13.1;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 52.2;Late spermatids: 178.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027497 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 143.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 160.7;Club cells: 114.2;Glandular and luminal cells: 167.1;Ionocytes: 159.4;Squamous epithelial cells: 159.9;Suprabasal keratinocytes: 193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 11 "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 30.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 68.2;Inhibitory neurons: 101.4;Microglial cells: 98.4;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 2 "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 307.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 24: Non-specific - Transcription" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 5 "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97761532 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.9;testis: 8.0" "Group enriched" "Detected in some" 15 "Astrocytes: 399.7;Early spermatids: 436.7;Excitatory neurons: 410.6;Inhibitory neurons: 845.7;Late spermatids: 229.2" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.1;prostate cancer: 7.6;Rhabdoid: 7.2" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" 2 Nucleoplasm "HPA007397: AB_2667821, HPA058047: AB_2683588" "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 23.8;parathyroid gland: 67.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 133.8;Inhibitory neurons: 164.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.5;Sarcoma: 26.4" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 81.6" CAB010496 Approved "Intracellular and membrane" Receptor NA NA 660000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 6 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 32.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Early spermatids: 2.4;Horizontal cells: 5.0;Late spermatids: 4.5;Oocytes: 5.1;Rod photoreceptor cells: 9.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enriched" "Detected in all" 5 "choroid plexus: 62.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 5 "cerebellum: 17.6" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134795260-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 188.6;dendritic cells: 110.3;Early spermatids: 45.0;Excitatory neurons: 46.3;Inhibitory neurons: 42.5;Late spermatids: 41.0;Oligodendrocyte precursor cells: 73.1" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 10.1;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 23 "dendritic cells: 23.3;granulocytes: 10.1" "Cancer enhanced" "Detected in many" "lymphoma: 10.5" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 3 "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.6" "Cell type enhanced" "Detected in many" "Ductal cells: 43.8;Enteroendocrine cells: 54.0;Intestinal goblet cells: 42.4;Oligodendrocytes: 71.0;Undifferentiated cells: 92.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor No No 380000 "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.2;Breast glandular cells: 44.2;Breast myoepithelial cells: 50.4;Enteroendocrine cells: 41.8;Squamous epithelial cells: 43.7;Suprabasal keratinocytes: 55.0;Undifferentiated cells: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.2;Endothelial cells: 58.3;Lymphatic endothelial cells: 69.6;Syncytiotrophoblasts: 198.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 5 "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 59.5;skin 1: 63.8" "Cell type enhanced" "Detected in many" "Mesothelial cells: 181.6;Muller glia cells: 193.3;Prostatic glandular cells: 76.9;Suprabasal keratinocytes: 105.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 70.9;cerebral cortex: 120.2;white matter: 83.2" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035784 Uncertain "Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 10: Muller glia cells - Visual perception" "Nuclear speckles" "HPA035784: AB_2674781" "unprognostic (1.90e-2)" "prognostic favorable (1.80e-4)" "unprognostic (7.08e-3)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (2.53e-3)" "unprognostic (3.15e-2)" "unprognostic (4.39e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.06e-3)" "unprognostic (3.18e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.16e-1)" "prognostic favorable (4.68e-5)" EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 84.7;Hofbauer cells: 37.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" Receptor NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 4 "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" EPSTI1 "BRESI1, MGC29634" ENSG00000133106 "Epithelial stromal interaction 1" Q96J88 13 42886388-42992271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 125.5;Extravillous trophoblasts: 188.8;Hofbauer cells: 88.4;Oocytes: 127.2;Proximal enterocytes: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017362 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" "HPA017362: AB_1848226" "unprognostic (2.06e-1)" "unprognostic (3.51e-1)" "unprognostic (1.80e-1)" "unprognostic (3.59e-2)" "unprognostic (2.35e-1)" "unprognostic (9.55e-2)" "unprognostic (2.31e-1)" "unprognostic (2.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.90e-2)" "unprognostic (3.91e-2)" "unprognostic (1.05e-3)" "unprognostic (8.13e-2)" EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "testis: 36.7" "Cell type enriched" "Detected in some" 18 "Early spermatids: 997.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" ERBB2 "c-ERB-2, c-ERB2, CD340, HER-2, HER2, MLN-19, NEU, NGL, p185(erbB2)" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Group enriched" "Detected in many" 5 "granulocytes: 1.2;T-cells: 5.0" "Group enriched" "Detected in all" 5 "breast cancer: 705.7;Esophageal cancer: 445.4;Gastric cancer: 199.3" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 980000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 49 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 207.6;Schwann cells: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" Receptor NA NA 450000 "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 19 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.9;fallopian tube: 10.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1916.0;Inhibitory neurons: 5860.5;Oligodendrocyte precursor cells: 2222.9;Oligodendrocytes: 977.4" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 61: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 14 "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" ERCC6L2 "C9orf102, FLJ37706, HEBO, RAD26L" ENSG00000182150 "ERCC excision repair 6 like 2" Q5T890 9 95871264-96121154 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 100.3;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021259, HPA021260, HPA021271, HPA022422" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" 2 "Nucleoplasm, Cytosol" "HPA021259: AB_1859542, HPA021260: AB_1859544, HPA021271: AB_1859543, HPA022422: " "unprognostic (6.70e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-1)" "unprognostic (1.28e-1)" "unprognostic (8.30e-2)" "unprognostic (3.62e-2)" "unprognostic (4.64e-2)" "unprognostic (3.92e-1)" "unprognostic (9.21e-2)" "unprognostic (3.21e-2)" "unprognostic (5.09e-2)" "unprognostic (1.32e-1)" "prognostic favorable (8.70e-5)" "unprognostic (3.63e-1)" "unprognostic (2.32e-1)" "unprognostic (1.07e-1)" "unprognostic (7.39e-2)" EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 127.2" "Cell type enriched" "Detected in many" 4 "monocytes: 3221.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 126.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047186, HPA054373" Uncertain Vesicles "Secreted to blood" "Growth factor" NA NA 46000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 5 Vesicles "HPA047186: , HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" ERG28 "C14orf1, NET51" ENSG00000133935 "Ergosterol biosynthesis 28 homolog" Q9UKR5 14 75649791-75660876 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 275.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043172 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Testis - Spermatid development" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Hepatocytes - Metabolism" 48 "HPA043172: AB_10793942" "unprognostic (2.68e-3)" "unprognostic (2.11e-2)" "unprognostic (4.55e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.66e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" "unprognostic (2.47e-1)" "unprognostic (3.01e-2)" "prognostic favorable (4.30e-5)" "unprognostic (1.28e-1)" "unprognostic (2.77e-1)" "unprognostic (9.58e-3)" "unprognostic (2.20e-1)" ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952792 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 477.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" ERGIC3 "C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84" ENSG00000125991 "ERGIC and golgi 3" Q9Y282 20 35542038-35557634 "Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 836.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015242, HPA015968" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 77: Plasma cells - Protein processing" 186 "HPA015242: AB_1848238, HPA015968: AB_1848239" "unprognostic (4.36e-2)" "unprognostic (3.43e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (2.20e-7)" "unprognostic (2.61e-1)" "unprognostic (2.90e-2)" "unprognostic (9.59e-2)" "unprognostic (8.59e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (9.81e-5)" "unprognostic (9.53e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (8.64e-2)" ERMAP "BTN5, RD, SC" ENSG00000164010 "Erythroblast membrane associated protein (Scianna blood group)" Q96PL5 1 42817122-42844991 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 65.9;Late spermatids: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA042573, HPA054672" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 4 "Golgi apparatus" Cytosol "HPA042573: AB_10794282, HPA054672: " "unprognostic (9.46e-2)" "unprognostic (4.47e-2)" "unprognostic (2.56e-3)" "unprognostic (1.15e-1)" "unprognostic (6.09e-2)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (7.48e-2)" "unprognostic (2.71e-3)" "unprognostic (6.46e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "unprognostic (8.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.48e-1)" "unprognostic (9.48e-2)" ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 52.5;Late spermatids: 47.9;Oocytes: 205.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 44: Oocytes - Unknown function" Cytosol "HPA041741: AB_10804116" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (2.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.24e-2)" "unprognostic (7.41e-3)" "unprognostic (1.96e-1)" "unprognostic (8.14e-2)" "unprognostic (1.66e-3)" "unprognostic (4.74e-2)" "unprognostic (3.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.31e-2)" ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5749832-5879537 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 56.4;Oligodendrocytes: 82.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 29 "HPA055582: " "unprognostic (1.93e-2)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.93e-2)" "unprognostic (2.97e-1)" "unprognostic (8.59e-2)" "unprognostic (4.30e-3)" "unprognostic (2.81e-1)" "unprognostic (5.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.14e-2)" "unprognostic (2.88e-2)" "prognostic favorable (5.83e-10)" "unprognostic (1.41e-1)" "unprognostic (4.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 51.3;pancreas: 64.7" "Cell type enhanced" "Detected in many" "dendritic cells: 245.5;monocytes: 264.9;Plasma cells: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cancer enriched" "Detected in all" 8 "Myeloma: 91.4" "Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 4 "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 18.7;gallbladder: 16.4;intestine: 28.0;salivary gland: 22.2;stomach 1: 50.5" "Cell type enhanced" "Detected in some" "Club cells: 56.5;Distal enterocytes: 92.0;Enteroendocrine cells: 39.6;Gastric mucus-secreting cells: 159.2;Intestinal goblet cells: 147.0;Ionocytes: 59.6;Undifferentiated cells: 37.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 13.3;colorectal cancer: 19.5;Gallbladder cancer: 8.9;Gastric cancer: 16.2;pancreatic cancer: 8.7" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transcription NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 35.8" "Cell type enriched" "Detected in some" 35 "Syncytiotrophoblasts: 667.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "testis cancer: 35.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 21 "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" ERVMER34-1 envMER34 ENSG00000226887 "Endogenous retrovirus group MER34 member 1, envelope" Q9H9K5 4 52722618-52751586 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 12.5;placenta: 10.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 80.5;Extravillous trophoblasts: 96.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA011423, HPA024053" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA 6000000 "Cluster 58: Placenta - Pregnancy" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA011423: AB_2668510, HPA024053: " "unprognostic (5.34e-2)" "unprognostic (1.29e-1)" "unprognostic (1.91e-3)" "unprognostic (5.86e-2)" "unprognostic (4.08e-4)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.88e-4)" "unprognostic (5.28e-2)" "unprognostic (2.99e-2)" "unprognostic (2.39e-3)" "unprognostic (2.62e-3)" "unprognostic (4.23e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-2)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" "unprognostic (1.82e-1)" ERVV-1 "ENVV1, FLJ32214, HERV-V1" ENSG00000269526 "Endogenous retrovirus group V member 1, envelope" B6SEH8 19 53013921-53016123 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "placenta: 15.5" "Cell type enriched" "Detected in some" 48 "Syncytiotrophoblasts: 396.2" "Cancer enhanced" "Detected in some" "renal cancer: 0.6;urothelial cancer: 0.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "testis cancer: 5.7" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Cytosol Centrosome "HPA076115: " "unprognostic (1.04e-3)" "unprognostic (7.32e-3)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.67e-2)" "unprognostic (9.92e-2)" "unprognostic (6.75e-2)" "unprognostic (4.34e-5)" "unprognostic (3.48e-2)" "unprognostic (5.80e-2)" "unprognostic (3.18e-1)" "unprognostic (1.35e-1)" ERVV-2 ENVV2 ENSG00000268964 "Endogenous retrovirus group V member 2, envelope" B6SEH9 19 53044740-53051680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "placenta: 8.1" "Cell type enriched" "Detected in some" 30 "Syncytiotrophoblasts: 90.3" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "testis cancer: 10.0" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Cytosol Centrosome "HPA076115: " "unprognostic (3.14e-3)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (4.33e-9)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.60e-4)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 380.0;Endothelial cells: 268.6;Smooth muscle cells: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 19.0;pancreatic cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.4;esophagus: 15.0;lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 18.7;Squamous epithelial cells: 8.1;Suprabasal keratinocytes: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 38: Non-specific - Transcription" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 19: NK-cells - Adaptive immune response" 2 "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 24000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Fibroblasts - ECM organization" 2 "Plasma membrane, Cytosol" "HPA002132: AB_1078807, HPA070823: " "unprognostic (2.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (5.72e-2)" "unprognostic (5.43e-2)" "unprognostic (9.01e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.13e-1)" "unprognostic (7.54e-2)" "unprognostic (6.70e-2)" "unprognostic (4.58e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (2.81e-5)" ESYT3 "CHR3SYT, FAM62C" ENSG00000158220 "Extended synaptotagmin 3" A0FGR9 3 138434586-138481686 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;skin 1: 7.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 26.0;Alveolar cells type 2: 30.8;Cone photoreceptor cells: 8.5;Excitatory neurons: 9.1;Inhibitory neurons: 9.3;Oocytes: 14.0;Rod photoreceptor cells: 7.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enhanced" "Detected in many" "hypothalamus: 7.3" "Low region specificity" "Detected in all" HPA039200 Approved NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 29: Non-specific - Unknown function" "Cluster 72: Alveolar cells - Lung function" 2 "HPA039200: AB_10805356" "unprognostic (4.48e-2)" "unprognostic (3.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.38e-4)" "unprognostic (2.23e-1)" "unprognostic (8.22e-2)" "unprognostic (3.55e-3)" "prognostic favorable (8.30e-4)" "unprognostic (3.38e-1)" "unprognostic (5.57e-2)" "unprognostic (6.19e-3)" "unprognostic (4.88e-3)" "unprognostic (3.16e-5)" "unprognostic (3.46e-1)" "unprognostic (1.12e-1)" "unprognostic (2.13e-1)" "unprognostic (6.43e-2)" ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158671968-158710742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 154.4;tongue: 167.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 177.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 68: Cardiomyocytes - Muscle contraction" 5 "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" 6 "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 185.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 64.4;Alveolar cells type 2: 48.2;Cytotrophoblasts: 41.6;Hepatocytes: 65.5;Proximal tubular cells: 57.7;Syncytiotrophoblasts: 153.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 81.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 83: Liver - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 4 Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" EVA1C "B18, B19, C21orf63, C21orf64, FAM176C, PRED34" ENSG00000166979 "Eva-1 homolog C" P58658 21 32412006-32515397 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 158.2;Ionocytes: 121.9;Late spermatids: 239.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.1;gdT-cell: 3.1;MAIT T-cell: 3.8;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.2;naive CD8 T-cell: 1.6;NK-cell: 3.2" "Group enriched" "Detected in many" 7 "granulocytes: 1.1;NK-cells: 3.2;T-cells: 3.8" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015720, HPA029944, CAB034174" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB034174: AB_1564317, HPA015720: AB_1845705, HPA029944: AB_10601092" "unprognostic (7.55e-3)" "unprognostic (8.91e-3)" "unprognostic (5.51e-2)" "unprognostic (2.55e-1)" "unprognostic (3.16e-2)" "prognostic favorable (5.06e-4)" "unprognostic (1.40e-3)" "unprognostic (4.24e-3)" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.84e-2)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.73e-1)" "unprognostic (5.95e-3)" "unprognostic (4.25e-3)" EVC "DWF-1, EVC1" ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.1;Microglial cells: 9.8" "Cancer enhanced" "Detected in all" "renal cancer: 16.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008703, HPA016046" Uncertain NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" "HPA008703: AB_1078765, HPA016046: AB_1848299" "unprognostic (1.69e-1)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (9.37e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.63e-2)" "unprognostic (2.82e-1)" "prognostic favorable (5.60e-9)" "unprognostic (3.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (9.47e-5)" EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 16.7;Leydig cells: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Connective tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" EVI2A "EVDA, EVI2" ENSG00000126860 "Ecotropic viral integration site 2A" P22794 17 31316410-31321749 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 163.9;lymphoid tissue: 102.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 184.8;Kupffer cells: 207.8;Langerhans cells: 132.9;Macrophages: 107.0;NK-cells: 96.7;Oligodendrocytes: 203.7;T-cells: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.0;Myeloma: 68.8" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045033 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 7 "Golgi apparatus, Plasma membrane" "HPA045033: AB_2679191" "unprognostic (7.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" "unprognostic (8.49e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.55e-4)" "unprognostic (1.90e-1)" "unprognostic (3.54e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.63e-6)" "unprognostic (7.64e-2)" "unprognostic (4.95e-2)" "unprognostic (5.87e-2)" "unprognostic (2.90e-2)" EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 186.9;lymphoid tissue: 165.3" "Cell type enhanced" "Detected in many" "B-cells: 221.7;Hofbauer cells: 195.7;Kupffer cells: 407.8;Langerhans cells: 189.3;Macrophages: 248.3;monocytes: 485.2;Schwann cells: 145.7;T-cells: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1371.1" "Group enriched" "Detected in all" 5 "granulocytes: 1371.1;monocytes: 383.9" "Group enriched" "Detected in many" 11 "Adrenocortical cancer: 21.0;Leukemia: 50.5;lymphoma: 45.6;Myeloma: 68.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Neutrophil_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Neutrophils - Degranulation" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 153.2;Oligodendrocytes: 185.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 46: Brainstem - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 18 "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" EVI5L ENSG00000142459 "Ecotropic viral integration site 5 like" Q96CN4 19 7830218-7864976 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 36.5;Late spermatids: 30.6;Oligodendrocyte precursor cells: 47.2;Oligodendrocytes: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043099, HPA043563" Approved Approved "Nuclear bodies" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 51: Oligodendrocytes - Unknown function" 10 "Nuclear bodies" "HPA043099: AB_10796685, HPA043563: AB_2678556" "unprognostic (3.90e-2)" "unprognostic (4.69e-2)" "unprognostic (9.29e-3)" "unprognostic (2.18e-2)" "unprognostic (1.74e-1)" "unprognostic (1.34e-2)" "unprognostic (2.06e-3)" "unprognostic (1.90e-2)" "unprognostic (7.66e-2)" "unprognostic (3.00e-1)" "unprognostic (7.48e-3)" "unprognostic (1.97e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (1.37e-2)" "unprognostic (2.04e-2)" EXD2 "C14orf114, EXDL2, FLJ10738" ENSG00000081177 "Exonuclease 3'-5' domain containing 2" Q9NVH0 14 69191498-69244020 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002906, HPA005848" Uncertain Approved "Intermediate filaments,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Mitochondria "Intermediate filaments" "HPA002906: AB_1078767, HPA005848: AB_1078768" "unprognostic (3.36e-2)" "unprognostic (1.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (9.91e-2)" "unprognostic (8.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.64e-2)" "unprognostic (8.97e-2)" "prognostic favorable (2.08e-9)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (8.75e-2)" "unprognostic (2.14e-2)" EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 120.8;Excitatory neurons: 221.7;Inhibitory neurons: 402.7;Microglial cells: 137.8;Oligodendrocyte precursor cells: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095648-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 39000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28756561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favorable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" F11R "CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1" ENSG00000158769 "F11 receptor" Q9Y624 1 160995211-161021343 "CD markers, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 200.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 166.2;neutrophil: 114.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 166.2" "Cancer enhanced" "Detected in all" "testis cancer: 214.6" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004671, HPA043616, HPA061700" Enhanced Supported "Cell Junctions,Microtubules" NA NA 1900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 18 Microtubules "Cell Junctions" "CAB004671: AB_425964, HPA043616: , HPA061700: AB_2684589" "unprognostic (1.60e-2)" "unprognostic (5.78e-3)" "unprognostic (1.78e-3)" "unprognostic (2.24e-1)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (2.28e-1)" "unprognostic (2.55e-1)" "unprognostic (6.35e-2)" "unprognostic (1.98e-3)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.50e-1)" "unprognostic (1.59e-1)" "unprognostic (9.72e-3)" "unprognostic (5.01e-2)" F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716126-76735770 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 67.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 46.3;Endothelial cells: 52.1;Fibroblasts: 62.0;Lymphatic endothelial cells: 46.9;Mucus glandular cells: 41.6;NK-cells: 90.1;Smooth muscle cells: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 25.5" "Group enriched" "Detected in many" 14 "NK-cells: 7.0;T-cells: 25.5" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB008973: , CAB012962: AB_2533198" "unprognostic (3.03e-1)" "unprognostic (7.76e-2)" "unprognostic (5.55e-2)" "unprognostic (7.76e-2)" "unprognostic (7.14e-2)" "unprognostic (3.46e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (2.21e-7)" "unprognostic (2.72e-3)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (6.74e-3)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.4;stomach 1: 42.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 74.3;Distal enterocytes: 85.0;Gastric mucus-secreting cells: 74.3;Glandular and luminal cells: 66.8;Intestinal goblet cells: 51.9;Proximal enterocytes: 56.1;Suprabasal keratinocytes: 97.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Heart muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 7 "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.4;lung: 32.4;thyroid gland: 18.6" "Cell type enhanced" "Detected in some" "Adipocytes: 105.5;Endothelial cells: 24.6;Lymphatic endothelial cells: 28.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 10.6" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 673.7;Basal respiratory cells: 344.3;Club cells: 387.7;Exocrine glandular cells: 355.4;Ionocytes: 309.6;Peritubular cells: 505.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 655.6" "Kidney - Podocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 603000 "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 194.9;stomach 1: 59.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 83.7;Oligodendrocyte precursor cells: 57.5;Oligodendrocytes: 286.6;Paneth cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Oligodendrocytes - Unknown function" 25 "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 119.2;Proximal enterocytes: 83.9;Spermatocytes: 78.6" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 32.7" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 214.2;dendritic cells: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Dendritic cells - Antigen presentation" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 348.0" "Cell type enriched" "Detected in many" 6 "Basal prostatic cells: 445.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006741, HPA079284" Approved Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Plasma membrane" "Endoplasmic reticulum" "HPA006741: AB_1078796, HPA079284: " "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.2;Alveolar cells type 1: 209.8;Extravillous trophoblasts: 150.6;Rod photoreceptor cells: 123.3;Schwann cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 30: Heart muscle - Heart development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" FADS6 ENSG00000172782 "Fatty acid desaturase 6" 17 74877302-74893781 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 10.1;epididymis: 17.5;intestine: 14.0" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 62.6" "Cancer enhanced" "Detected in some" "liver cancer: 2.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016802 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 22: Proximal enterocytes - Digestion" "HPA016802: AB_2669448" "unprognostic (2.41e-2)" "unprognostic (6.80e-3)" "unprognostic (2.64e-1)" "unprognostic (4.68e-3)" "unprognostic (4.73e-2)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (6.41e-2)" "unprognostic (6.98e-4)" "unprognostic (3.38e-2)" "unprognostic (7.53e-2)" "unprognostic (1.14e-2)" "unprognostic (6.71e-2)" "unprognostic (2.27e-1)" "unprognostic (8.45e-2)" "unprognostic (1.79e-1)" FAF2 "ETEA, KIAA0887, UBXD8, UBXN3B" ENSG00000113194 "Fas associated factor family member 2" Q96CS3 5 176447628-176510074 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065968, HPA071246, HPA073828" Approved Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA 12000 "Cluster 13: Non-specific - Mitochondria" "Cluster 40: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 77: Plasma cells - Protein processing" 3 "Lipid droplets" "Endoplasmic reticulum" "HPA065968: AB_2685589, HPA071246: AB_2732176, HPA073828: AB_2686636" "unprognostic (6.25e-3)" "unprognostic (9.61e-2)" "unprognostic (3.52e-3)" "unprognostic (1.02e-3)" "unprognostic (4.74e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (6.02e-2)" "unprognostic (2.68e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (2.74e-3)" "unprognostic (9.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.56e-3)" "unprognostic (1.48e-1)" FAIM2 "KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2" ENSG00000135472 "Fas apoptotic inhibitory molecule 2" Q9BWQ8 12 49866896-49904217 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 337.0;parathyroid gland: 94.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 116.7;Early spermatids: 268.0;Excitatory neurons: 75.0;Horizontal cells: 157.4;Inhibitory neurons: 100.5;Oligodendrocytes: 51.7" "Cancer enriched" "Detected in many" 8 "glioma: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.0" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 38.5" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018790, HPA048800" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Early spermatids - Unknown function" 1 "Intermediate filaments" "HPA018790: AB_1852822, HPA048800: AB_2680526" "unprognostic (1.74e-1)" "unprognostic (5.98e-4)" "unprognostic (2.22e-1)" "unprognostic (9.75e-3)" "unprognostic (3.36e-2)" "unprognostic (2.61e-4)" "unprognostic (2.62e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (1.75e-2)" "unprognostic (5.66e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-6)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.47e-1)" "unprognostic (6.78e-4)" FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384161-122412334 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 584.2;Distal enterocytes: 660.7;Suprabasal keratinocytes: 538.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.0" "Cell type enhanced" "Detected in many" "Adipocytes: 31.8;Early spermatids: 21.6;Lymphatic endothelial cells: 31.5;Salivary duct cells: 21.4;Sertoli cells: 27.2;Smooth muscle cells: 86.5" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 7.7;testis cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" FAM163B C9orf166 ENSG00000196990 "Family with sequence similarity 163 member B" P0C2L3 9 133577081-133609389 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 82.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 24.0;Inhibitory neurons: 17.0;Late spermatids: 27.2" "Cancer enriched" "Detected in some" 6 "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 12.9" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067336 Enhanced Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" 2 "Nuclear bodies, Plasma membrane, Cytosol" "HPA067336: AB_2685825" "unprognostic (2.94e-2)" "unprognostic (6.87e-3)" "unprognostic (2.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.23e-2)" "unprognostic (9.05e-2)" "unprognostic (1.02e-2)" "unprognostic (3.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (5.75e-4)" "unprognostic (1.07e-1)" "unprognostic (9.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.73e-4)" FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 104.0" "Cell type enhanced" "Detected in many" "Astrocytes: 250.2;Cholangiocytes: 89.7;Excitatory neurons: 161.3;Inhibitory neurons: 73.5;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 11: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 1 "Plasma membrane" Nucleoplasm "HPA051345: AB_2681449" "unprognostic (3.60e-2)" "unprognostic (7.15e-2)" "unprognostic (2.21e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (4.11e-2)" "unprognostic (9.84e-2)" "unprognostic (9.19e-2)" "unprognostic (2.28e-1)" "unprognostic (3.97e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.71e-5)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (4.90e-6)" "unprognostic (3.28e-2)" FAM171A2 MGC34829 ENSG00000161682 "Family with sequence similarity 171 member A2" A8MVW0 17 44353215-44363853 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4;pituitary gland: 7.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 42.7;Horizontal cells: 30.8;Muller glia cells: 119.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.4" "Pancreas - Alpha cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019770 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "HPA019770: AB_1848383" "unprognostic (1.28e-2)" "unprognostic (2.07e-2)" "unprognostic (4.14e-3)" "unprognostic (8.47e-2)" "unprognostic (9.98e-2)" "unprognostic (1.92e-1)" "unprognostic (1.62e-4)" "unprognostic (5.76e-2)" "unprognostic (1.98e-2)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (3.00e-1)" "unprognostic (2.43e-3)" "unprognostic (1.06e-1)" "unprognostic (1.38e-1)" "unprognostic (2.36e-2)" "unprognostic (4.76e-2)" FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.7" "Cell type enhanced" "Detected in many" "Astrocytes: 245.2;Bipolar cells: 129.0;Excitatory neurons: 122.1;Inhibitory neurons: 109.3;Oligodendrocyte precursor cells: 95.7;Oligodendrocytes: 73.0;Serous glandular cells: 62.9" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Sarcoma: 39.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010529, HPA010639, HPA013434" Approved Approved Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "Nucleoli, Cytosol" "HPA010529: , HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" FAM174A "NS5ATP6, TMEM157, UNQ1912" ENSG00000174132 "Family with sequence similarity 174 member A" Q8TBP5 5 100535374-100586741 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 55.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 55.9" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019539 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 3: Choroid plexus - Cilium" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 31 "Golgi apparatus" Cytosol "HPA019539: AB_2293743" "unprognostic (2.34e-1)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (9.02e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (5.55e-3)" "unprognostic (3.06e-1)" "unprognostic (2.60e-1)" "unprognostic (3.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.73e-2)" "unprognostic (7.69e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 74.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 75.6;Intestinal goblet cells: 64.1;Late spermatids: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 66.4" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Intermediate filaments" "HPA015306: AB_2669182" "unprognostic (3.00e-3)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "prognostic favorable (9.03e-5)" "unprognostic (4.68e-2)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (8.23e-3)" "unprognostic (7.67e-3)" "unprognostic (5.05e-3)" "unprognostic (6.60e-2)" "unprognostic (1.33e-1)" "unprognostic (4.67e-2)" "unprognostic (2.01e-1)" "unprognostic (6.64e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-2)" FAM174C "C19orf24, FLJ20640" ENSG00000228300 "Family with sequence similarity 174 member C" Q9BVV8 19 1275530-1279244 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 310.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043279, HPA047026" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA043279: AB_10794656, HPA047026: AB_2679906" "unprognostic (1.10e-1)" "unprognostic (3.39e-1)" "unprognostic (1.12e-1)" "unprognostic (1.65e-3)" "unprognostic (7.05e-2)" "unprognostic (4.90e-1)" "unprognostic (4.23e-3)" "unprognostic (3.12e-2)" "unprognostic (1.18e-1)" "unprognostic (3.59e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (1.81e-1)" "unprognostic (2.54e-3)" "unprognostic (2.16e-1)" "unprognostic (1.10e-1)" "unprognostic (2.25e-2)" FAM187B "FLJ25660, TMEM162" ENSG00000177558 "Family with sequence similarity 187 member B" Q17R55 19 35224800-35228739 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 241 "testis: 66.8" "Cell type enriched" "Detected in some" 11 "Late spermatids: 2674.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA079535 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 63: Late spermatids - Spermatogenesis" "HPA079535: " "unprognostic (3.34e-1)" "unprognostic (4.96e-1)" "unprognostic (2.40e-1)" "unprognostic (2.84e-1)" "unprognostic (2.72e-1)" "unprognostic (2.12e-1)" "unprognostic (1.25e-3)" "unprognostic (2.71e-1)" "unprognostic (2.49e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-2)" FAM205A C9orf144B ENSG00000205108 "Family with sequence similarity 205 member A" Q6ZU69 9 34723053-34729488 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 240 "testis: 24.1" "Cell type enriched" "Detected in some" 6 "Early spermatids: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA071267 Enhanced Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 21: Early spermatids - Spermatogenesis" "Plasma membrane" "Nucleoli fibrillar center" "HPA071267: AB_2686376" "unprognostic (2.25e-1)" "unprognostic (3.66e-3)" "unprognostic (6.29e-3)" "unprognostic (1.90e-1)" "unprognostic (2.73e-3)" "unprognostic (7.82e-2)" "unprognostic (9.61e-2)" "unprognostic (6.41e-2)" "unprognostic (4.78e-1)" "unprognostic (7.34e-2)" FAM209A "C20orf106, dJ1153D9.3" ENSG00000124103 "Family with sequence similarity 209 member A" Q5JX71 20 56517187-56526152 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 101.3" "Group enriched" "Detected in some" 183 "Early spermatids: 2058.5;Late spermatids: 739.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA079442 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 44: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" 199 "Plasma membrane, Cell Junctions" "HPA079442: " "unprognostic (1.03e-1)" "unprognostic (1.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (8.58e-3)" "unprognostic (1.06e-2)" "unprognostic (2.12e-1)" "unprognostic (2.10e-1)" "unprognostic (9.83e-2)" "unprognostic (5.56e-3)" "unprognostic (7.68e-2)" "unprognostic (1.86e-9)" "unprognostic (2.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-2)" FAM209B "C20orf107, dJ1153D9.4" ENSG00000213714 "Family with sequence similarity 209 member B" Q5JX69 20 56533246-56536520 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 111.2" "Group enriched" "Detected in some" 104 "Early spermatids: 1649.5;Late spermatids: 519.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA042144 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 21: Early spermatids - Spermatogenesis" "HPA042144: AB_10794414" "unprognostic (2.93e-1)" "unprognostic (6.90e-2)" "unprognostic (9.49e-3)" "unprognostic (4.96e-3)" "unprognostic (1.72e-1)" "unprognostic (3.77e-1)" "unprognostic (1.72e-1)" "unprognostic (7.77e-2)" "unprognostic (3.63e-2)" "unprognostic (1.43e-1)" "unprognostic (4.59e-4)" "unprognostic (3.47e-1)" "unprognostic (2.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.55e-1)" "unprognostic (7.13e-2)" "unprognostic (1.48e-4)" FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: AB_2668972, HPA051564: AB_2681536" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (5.78e-2)" "unprognostic (9.18e-3)" "unprognostic (4.13e-2)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.23e-3)" "unprognostic (1.11e-2)" "unprognostic (2.26e-1)" "unprognostic (5.53e-3)" "unprognostic (6.79e-3)" "unprognostic (2.98e-2)" "unprognostic (3.27e-3)" "unprognostic (7.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" "unprognostic (4.82e-2)" FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 56: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 1: Erythroid cells - Oxygen transport" 55 "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Approved Nucleoplasm,Mitochondria NA NA 5300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria Nucleoplasm "HPA011651: , HPA071871: AB_2732188" "unprognostic (1.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.49e-1)" "unprognostic (4.80e-2)" "unprognostic (5.51e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 22.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.2;Excitatory neurons: 20.0" "Cancer enhanced" "Detected in all" "breast cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "Endoplasmic reticulum" "HPA010803: AB_1079200, HPA010850: AB_2732402" "unprognostic (1.85e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-3)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (8.03e-3)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (3.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (5.22e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (7.62e-2)" FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 268.1;Endothelial cells: 98.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" FAM241B C10orf35 ENSG00000171224 "Family with sequence similarity 241 member B" Q96D05 10 69630247-69633596 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.9" "Cell type enhanced" "Detected in many" "Early spermatids: 41.2;Late spermatids: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "gdT-cell: 4.3;MAIT T-cell: 10.9;memory CD4 T-cell: 10.6;memory CD8 T-cell: 7.0;naive CD4 T-cell: 17.2;naive CD8 T-cell: 5.8;T-reg: 7.8" "Lineage enriched" "Detected in single" 25 "T-cells: 17.2" "Low cancer specificity" "Detected in all" "Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA034591 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 29: Forebrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Nucleoplasm, Centrosome" Cytosol "HPA034591: AB_10670572" "unprognostic (1.12e-1)" "unprognostic (6.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.17e-1)" "unprognostic (7.17e-3)" "prognostic unfavorable (8.64e-4)" "prognostic unfavorable (1.03e-4)" "unprognostic (3.56e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" "unprognostic (3.37e-2)" "unprognostic (3.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-1)" "prognostic favorable (9.72e-4)" FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" "No annotated function" Yes No 15000 "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 138.6;pancreas: 206.1;salivary gland: 116.0;stomach 1: 111.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 311.2;Exocrine glandular cells: 293.7;Proximal enterocytes: 846.1;Serous glandular cells: 260.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Region enriched" "Detected in single" 9 "choroid plexus: 2.3" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "breast cancer: 12.3;colorectal cancer: 8.6;lung cancer: 7.7" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" Cytokine NA NA 2080000 250000 "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 3 Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 257.4;intestine: 472.8;salivary gland: 454.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 358.6;Distal enterocytes: 916.6;Enteroendocrine cells: 310.4;Intestinal goblet cells: 1087.5;Ionocytes: 340.2;Paneth cells: 568.5;Proximal enterocytes: 348.8;Serous glandular cells: 586.3;Undifferentiated cells: 430.5" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 6 "colorectal cancer: 29.2;Gastric cancer: 13.6" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" "No annotated function" NA NA 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" FAM76B MGC33371 ENSG00000077458 "Family with sequence similarity 76 member B" Q5HYJ3 11 95768953-95790409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Group enriched" "Detected in all" 7 "Early spermatids: 246.3;Late spermatids: 406.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036608 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 8 Nucleoplasm "Nucleoli fibrillar center" "HPA036608: AB_2675215" "unprognostic (8.17e-2)" "unprognostic (2.26e-1)" "unprognostic (8.21e-2)" "unprognostic (2.39e-2)" "unprognostic (3.12e-2)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (2.64e-2)" "unprognostic (1.01e-2)" "unprognostic (1.65e-2)" "unprognostic (1.22e-1)" "unprognostic (3.90e-3)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (2.43e-1)" "prognostic favorable (2.72e-4)" FAM8A1 AHCP ENSG00000137414 "Family with sequence similarity 8 member A1" Q9UBU6 6 17600302-17611719 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 682.1;Late spermatids: 358.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044698, HPA073675" Approved Approved "Golgi apparatus" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Golgi apparatus" "HPA044698: AB_2679051, HPA073675: AB_2732236" "unprognostic (4.06e-1)" "unprognostic (2.32e-1)" "unprognostic (9.11e-2)" "unprognostic (6.90e-2)" "unprognostic (1.99e-2)" "unprognostic (5.17e-3)" "unprognostic (6.13e-2)" "unprognostic (1.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.09e-3)" "unprognostic (4.44e-2)" "unprognostic (3.50e-1)" "unprognostic (1.56e-2)" "unprognostic (3.85e-2)" "unprognostic (3.71e-1)" "unprognostic (7.59e-2)" "unprognostic (2.98e-1)" FAM98B FLJ38426 ENSG00000171262 "Family with sequence similarity 98 member B" Q52LJ0 15 38454127-38487710 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008320, HPA008502" Enhanced Supported Nucleoplasm,Vesicles NA NA 20000 "Cluster 22: Eosinophils - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 1 "Nucleoplasm, Vesicles" "HPA008320: AB_1848419, HPA008502: AB_1848420" "unprognostic (1.05e-2)" "unprognostic (3.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-2)" "unprognostic (1.54e-2)" "unprognostic (3.09e-2)" "unprognostic (9.25e-3)" "unprognostic (1.74e-1)" "unprognostic (4.69e-2)" "unprognostic (2.18e-1)" "unprognostic (3.15e-1)" "unprognostic (3.15e-2)" "unprognostic (1.51e-2)" "unprognostic (2.26e-1)" "unprognostic (4.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30890559-30943108 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: AB_2680311" "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89726683-89816977 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.0" "Cell type enhanced" "Detected in many" "Oocytes: 24.3;Spermatocytes: 47.5;Spermatogonia: 30.0;Syncytiotrophoblasts: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Cell proliferation" 6 Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.3;lymphoid tissue: 43.2;testis: 31.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.8;Oocytes: 53.7;Spermatocytes: 79.9;Spermatogonia: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cell proliferation" 3 Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 203.3;Oligodendrocytes: 406.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 1 Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149016-29341121 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.3;Inhibitory neurons: 165.2;Microglial cells: 60.8;Syncytiotrophoblasts: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 39.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Small intestine - Absorption" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88953813-89029605 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.0;Secretory cells: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 101.1" "Group enriched" "Detected in all" 5 "granulocytes: 101.1;T-cells: 90.6" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 11900000 420000 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 8 "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.6" "Group enriched" "Detected in some" 7 "NK-cells: 71.7;T-cells: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.2" "Group enriched" "Detected in many" 9 "NK-cells: 41.6;T-cells: 58.2" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" Cytokine NA NA 73600 "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 19: NK-cells - Adaptive immune response" 28 "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 84.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 111.6;Salivary duct cells: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 4600000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504092-151591331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 226.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 35.1;Basal respiratory cells: 30.6;Basal squamous epithelial cells: 34.1;Extravillous trophoblasts: 23.1;Serous glandular cells: 22.9;Squamous epithelial cells: 54.2;Suprabasal keratinocytes: 42.1" "Group enriched" "Detected in many" 6 "cervical cancer: 13.9;head and neck cancer: 21.4;lung cancer: 6.1;urothelial cancer: 5.6" "Region enriched" "Detected in all" 6 "cerebellum: 234.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 27.8;Gallbladder cancer: 40.3;head and neck cancer: 50.9" "Testis - Late spermatids" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 58 "cerebellum: 313.3" "CAB033680, HPA044656" Enhanced Uncertain Vesicles NA NA 300000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" Vesicles "CAB033680: AB_2100956, HPA044656: " "unprognostic (8.06e-3)" "unprognostic (6.01e-2)" "unprognostic (3.47e-1)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (4.43e-1)" "unprognostic (9.78e-3)" "unprognostic (2.28e-1)" "unprognostic (8.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-7)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (3.64e-3)" FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 252.0;Excitatory neurons: 496.5;Inhibitory neurons: 142.1;Oligodendrocyte precursor cells: 83.0" "Cancer enriched" "Detected in single" 6 "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 4700 "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Cell Junctions" "HPA026878: AB_1848430, HPA074824: " "unprognostic (5.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.76e-6)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-1)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-4)" "unprognostic (8.83e-2)" "unprognostic (7.72e-2)" "unprognostic (2.25e-1)" FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Endothelial cells: 28.9;Fibroblasts: 25.0;Inhibitory neurons: 33.2;Microglial cells: 22.4;Oligodendrocytes: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 18.4" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 62: Connective tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" FATE1 "CT43, FATE" ENSG00000147378 "Fetal and adult testis expressed 1" Q969F0 X 151716035-151723194 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "testis: 232.3" "Group enriched" "Detected in some" 7 "Late spermatids: 57.1;Sertoli cells: 201.3" "Cancer enriched" "Detected in some" 5 "testis cancer: 6.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA034604 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 63: Late spermatids - Spermatogenesis" 78 "HPA034604: AB_10602318" "unprognostic (1.82e-2)" "unprognostic (7.13e-2)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.40e-5)" "unprognostic (2.10e-1)" "unprognostic (3.70e-3)" "unprognostic (2.58e-1)" "unprognostic (1.16e-1)" "unprognostic (5.07e-3)" "unprognostic (1.55e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (4.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.68e-1)" "unprognostic (5.34e-2)" FBH1 "Fbx18, FBXO18, FLJ14590" ENSG00000134452 "F-box DNA helicase 1" Q8NFZ0 10 5890203-5937594 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002844 Supported NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" 3 "HPA002844: AB_1078829" "unprognostic (3.14e-2)" "unprognostic (1.55e-1)" "unprognostic (6.35e-3)" "unprognostic (4.42e-2)" "unprognostic (3.37e-2)" "unprognostic (8.98e-3)" "prognostic unfavorable (7.73e-7)" "unprognostic (1.89e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (6.91e-3)" "unprognostic (3.69e-1)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (9.54e-2)" FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 42.0" "Group enriched" "Detected in all" 7 "Astrocytes: 256.1;Excitatory neurons: 549.1;Inhibitory neurons: 554.2;Microglial cells: 195.9;Oligodendrocyte precursor cells: 283.9;Oligodendrocytes: 238.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 31.9" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 60: Prostate cancer - Unknown function" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm "HPA036410: AB_2675109, HPA036411: AB_10669603" "unprognostic (8.15e-2)" "unprognostic (3.77e-2)" "unprognostic (2.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.58e-2)" "unprognostic (2.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.08e-2)" "unprognostic (5.98e-2)" "unprognostic (6.30e-2)" "prognostic favorable (4.60e-8)" "unprognostic (1.86e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.35e-2)" FBXW12 "Fbw12, FBXO35" ENSG00000164049 "F-box and WD repeat domain containing 12" Q6X9E4 3 48372219-48401259 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "pancreas: 5.9" "Cell type enriched" "Detected in some" 8 "Oocytes: 96.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA037491, HPA037492" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Oocytes - Unknown function" Cytosol Vesicles "HPA037491: AB_2675504, HPA037492: AB_2675505" "unprognostic (5.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.81e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-2)" "unprognostic (8.56e-2)" "unprognostic (2.17e-1)" "unprognostic (9.48e-2)" "unprognostic (2.95e-1)" "unprognostic (1.21e-3)" "unprognostic (6.96e-3)" "unprognostic (2.36e-1)" "unprognostic (6.29e-3)" "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (8.81e-3)" FCAMR "CD351, FCA/MR, Fcalpha/muR, FKSG87" ENSG00000162897 "Fc alpha and mu receptor" Q8WWV6 1 206957965-206970625 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 36.7;lymphoid tissue: 25.5" "Group enriched" "Detected in some" 14 "Distal tubular cells: 6.1;Proximal tubular cells: 24.0" "Group enriched" "Detected in some" 5 "liver cancer: 2.4;renal cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056505 Enhanced NA NA 5300000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA056505: AB_2732604" "unprognostic (2.94e-1)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (2.92e-1)" "unprognostic (7.44e-2)" "unprognostic (4.55e-3)" "unprognostic (2.69e-3)" "unprognostic (1.08e-4)" "unprognostic (3.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" FCAR "CD89, FcalphaR, FcalphaRI" ENSG00000186431 "Fc alpha receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 25.9;lung: 10.2;lymphoid tissue: 13.1" "Group enriched" "Detected in some" 5 "Kupffer cells: 13.9;Macrophages: 20.4;monocytes: 47.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.3;neutrophil: 4.1" "Group enriched" "Detected in many" 27 "granulocytes: 4.1;monocytes: 1.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" FCER1A "FCE1A, FcepsilonRIalpha, FCERIA" ENSG00000179639 "Fc epsilon receptor Ia" P12319 1 159289714-159308224 "FDA approved drug targets, Predicted membrane proteins" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 36.2" "Cell type enriched" "Detected in some" 11 "Langerhans cells: 2592.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 21795.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 21795.4" "Group enriched" "Detected in some" 116 "Leukemia: 39.1;lymphoma: 10.8" "Skin - Langerhans cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 1.0" "CAB022102, HPA036051, CAB055526" Approved NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 13: Skin - Cornification" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" 1 "CAB022102: , CAB055526: , HPA036051: AB_2674919" "unprognostic (1.78e-2)" "unprognostic (2.26e-2)" "unprognostic (7.32e-2)" "unprognostic (7.51e-2)" "unprognostic (1.32e-2)" "unprognostic (1.44e-3)" "unprognostic (7.19e-2)" "unprognostic (1.97e-3)" "unprognostic (2.44e-1)" "unprognostic (7.20e-2)" "unprognostic (8.54e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.20e-4)" "unprognostic (1.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (3.39e-2)" FCER1G FcepsilonRIgamma ENSG00000158869 "Fc epsilon receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.7;lymphoid tissue: 458.8" "Cell type enhanced" "Detected in many" "dendritic cells: 923.3;granulocytes: 1001.3;Hofbauer cells: 2835.1;Kupffer cells: 1729.0;Langerhans cells: 1885.6;Macrophages: 1764.5;monocytes: 3873.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 7025.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 55.5;lymphoma: 18.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 3 "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" FCER2 "CD23, CD23A, CLEC4J, FCE2, FcepsilonRII, FCErII" ENSG00000104921 "Fc epsilon receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 41.0" "Cell type enriched" "Detected in some" 16 "B-cells: 141.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 2.8" "Group enriched" "Detected in many" 24 "memory B-cell: 201.7;naive B-cell: 497.3" "Lineage enriched" "Detected in many" 34 "B-cells: 497.3" "Group enriched" "Detected in some" 16 "Leukemia: 49.4;lymphoma: 34.1;Myeloma: 41.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" Receptor NA NA 240000 "Cluster 18: Non-specific - Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" FCGR1A "CD64, CD64A, FCG1, FcgammaRI, FcgammaRIa, FCGR1" ENSG00000150337 "Fc gamma receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 98.2" "Group enriched" "Detected in some" 5 "Hofbauer cells: 236.8;Kupffer cells: 103.7;Late spermatids: 60.3;Macrophages: 79.6" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 137.1;intermediate monocyte: 57.3;myeloid DC: 37.3;neutrophil: 98.7" "Group enriched" "Detected in many" 55 "dendritic cells: 37.3;granulocytes: 98.7;monocytes: 137.1" "Cancer enriched" "Detected in single" 27 "Leukemia: 25.7" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 18 Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" FCGR2A "CD32, CD32A, CDw32, Fc-gamma-RIIa, FCG2, FcgammaRIIa, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc gamma receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 116.9;placenta: 130.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 201.0;Kupffer cells: 179.0;Langerhans cells: 422.4;Macrophages: 294.0;monocytes: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2531.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 2531.1" "Cancer enriched" "Detected in some" 5 "Leukemia: 40.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA010718, HPA010776, HPA014730" Supported Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" FCGR2B "CD32, CD32B, FCG2, FcgammaRIIb, FCGR2, FcGRIIB" ENSG00000072694 "Fc gamma receptor IIb" P31994 1 161663143-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 389.2" "Cell type enhanced" "Detected in many" "B-cells: 63.1;Endothelial cells: 81.2;Fibroblasts: 53.7;Kupffer cells: 52.9;Langerhans cells: 332.8;Macrophages: 125.2;Plasma cells: 61.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 328.6;memory B-cell: 203.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 10.4;lymphoma: 25.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Sinusoid Endothelial cells, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB007796, HPA014730" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 5 "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" FCGR2C "CD32C, Fc-gamma-RIIc, FcgammaRIIc, hFcRII-C" ENSG00000244682 "Fc gamma receptor IIc (gene/pseudogene)" 1 161581339-161605662 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "placenta: 27.3" "Cell type enhanced" "Detected in some" "B-cells: 7.9;Langerhans cells: 24.5;Late spermatids: 7.7;Lymphatic endothelial cells: 7.4;Macrophages: 24.5;monocytes: 10.4;Schwann cells: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Skeletal muscle - Macrophages" "HPA010718, HPA010776, HPA014730" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (3.64e-2)" "unprognostic (1.61e-1)" "unprognostic (2.08e-2)" "unprognostic (2.43e-1)" "unprognostic (1.64e-3)" "unprognostic (3.81e-3)" "unprognostic (7.73e-2)" "unprognostic (9.60e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-2)" "unprognostic (3.05e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (2.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.23e-2)" "unprognostic (2.42e-1)" FCGR3A "CD16, CD16a, FCG3, FcgammaRIIIa, FCGR3, FcGRIIIA" ENSG00000203747 "Fc gamma receptor IIIa" P08637 1 161541759-161550968 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 202.0;lymphoid tissue: 294.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 240.5;Kupffer cells: 656.2;Macrophages: 303.8;monocytes: 1050.2;NK-cells: 597.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1806.3;non-classical monocyte: 4107.1" "Lineage enriched" "Detected in all" 6 "monocytes: 4107.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" Receptor NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" FCGRT "FcgammaRn, FcRn" ENSG00000104870 "Fc gamma receptor and transporter" P55899 19 49506816-49526428 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1392.0;Paneth cells: 775.0;Proximal enterocytes: 1822.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2360.0" "Group enriched" "Detected in all" 17 "dendritic cells: 924.4;granulocytes: 2360.0;monocytes: 1367.7" "Cancer enhanced" "Detected in all" "Bone cancer: 261.3" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 8: Immune cells - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" 5 "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" FCMR "FAIM3, FcmuR, TOSO" ENSG00000162894 "Fc mu receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 63.7;lymphoid tissue: 175.4" "Group enriched" "Detected in many" 5 "B-cells: 334.0;NK-cells: 96.0;T-cells: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Leukemia: 23.9;lymphoma: 55.8;Myeloma: 45.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003910 Approved Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" Immunity NA NA 5500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "Plasma membrane, Focal adhesion sites" "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" FCRL1 "CD307a, FCRH1, IFGP1, IRTA5" ENSG00000163534 "Fc receptor like 1" Q96LA6 1 157794403-157820120 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "bone marrow: 8.0;intestine: 8.4;lymphoid tissue: 26.6" "Cell type enriched" "Detected in some" 32 "B-cells: 99.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 39.4;naive B-cell: 68.3" "Lineage enriched" "Detected in many" 62 "B-cells: 68.3" "Cancer enriched" "Detected in single" 36 "lymphoma: 9.1" "Heart muscle - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA013323 Enhanced NA NA 290000 "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "HPA013323: AB_1848480" "unprognostic (6.52e-4)" "unprognostic (3.49e-3)" "unprognostic (8.68e-3)" "unprognostic (8.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.47e-2)" "unprognostic (5.48e-3)" "unprognostic (1.40e-2)" "unprognostic (4.30e-2)" "unprognostic (1.81e-1)" "unprognostic (2.85e-2)" "unprognostic (1.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.65e-2)" "unprognostic (4.80e-2)" "unprognostic (6.74e-2)" FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 48.3" "Cell type enhanced" "Detected in some" "B-cells: 45.6;Late spermatids: 10.6;NK-cells: 28.7;T-cells: 9.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.4" "Group enriched" "Detected in many" 54 "B-cells: 35.4;NK-cells: 20.5;T-cells: 19.1" "Cancer enriched" "Detected in single" 81 "lymphoma: 17.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Testis - Late spermatids" "Low region specificity" "Detected in many" HPA048022 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.2" "Cell type enhanced" "Detected in single" "B-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.7" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 8 "HPA054030: " "unprognostic (6.06e-2)" "unprognostic (3.41e-3)" "unprognostic (2.57e-1)" "unprognostic (5.08e-2)" "unprognostic (4.69e-4)" "unprognostic (2.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (3.37e-1)" "unprognostic (6.77e-2)" FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 95.7" "Group enriched" "Detected in some" 4 "B-cells: 129.6;Melanocytes: 34.4" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 369.4;naive B-cell: 342.8" "Lineage enriched" "Detected in many" 10 "B-cells: 369.4" "Cancer enriched" "Detected in some" 5 "lymphoma: 220.7" "Skin - Melanocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" Other NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 465.5;Ionocytes: 394.7;Oocytes: 407.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 12 "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favorable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favorable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 42.0" "Cell type enhanced" "Detected in some" "Early spermatids: 13.7;Gastric mucus-secreting cells: 31.2;Intestinal goblet cells: 7.8;Late spermatids: 30.6" "Group enriched" "Detected in some" 6 "pancreatic cancer: 4.2;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054117 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA054117: AB_2682387" "unprognostic (1.90e-1)" "unprognostic (3.08e-3)" "unprognostic (2.06e-3)" "unprognostic (3.91e-2)" "unprognostic (2.09e-1)" "unprognostic (9.49e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (3.32e-2)" "unprognostic (3.23e-6)" "unprognostic (7.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.79e-3)" "unprognostic (6.39e-2)" FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35347902-35353864 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 3.0;brain: 2.3;ovary: 2.4;pancreas: 2.4" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 5.9;Granulosa cells: 4.6;Pancreatic endocrine cells: 6.8" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cancer enhanced" "Detected in single" "lymphoma: 1.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.0;lymphoid tissue: 21.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 33.1;Hofbauer cells: 21.7;Intestinal goblet cells: 15.8;Macrophages: 14.7;monocytes: 77.8" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.8" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.8" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;prostate cancer: 2.8" "Breast - Endothelial cells, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023985 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Neutrophils - Degranulation" 93 "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.9;lymphoid tissue: 2.4" "Group enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 15.3;granulocytes: 11.2;Macrophages: 7.5;monocytes: 28.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" "Breast - Endothelial cells" HPA044681 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 29: Monocytes - Innate immune response" 12 "HPA044681: AB_2679043" "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adipose tissue: 3.9;intestine: 11.0;lung: 3.4;pituitary gland: 10.7" "Cell type enhanced" "Detected in some" "Early spermatids: 30.4;Intestinal goblet cells: 81.8;Late spermatids: 19.1;Pancreatic endocrine cells: 22.1;Paneth cells: 12.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Testis - Late spermatids, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 188.4;Leydig cells: 193.1;Oligodendrocyte precursor cells: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 200.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 13 "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Lacrimo-auriculo-dento-digital syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 594.1" "Group enriched" "Detected in many" 5 "Astrocytes: 216.4;Cholangiocytes: 190.8;Oligodendrocytes: 523.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 3.0;eosinophil: 2.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Gastric cancer: 171.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" Receptor NA NA 1200000 "Cluster 46: Basophils - Proteolysis" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 7 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.8;esophagus: 135.7;skin 1: 264.2" "Cell type enhanced" "Detected in many" "Astrocytes: 389.2;Basal keratinocytes: 98.3;Cholangiocytes: 70.6;Suprabasal keratinocytes: 96.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 150.3" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" Receptor NA NA 2500000 "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Astrocytes - Unknown function" 192 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5;lung: 63.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.1;Enteroendocrine cells: 17.0;Hepatocytes: 23.4;Proximal tubular cells: 17.0;Undifferentiated cells: 32.0" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 117.0" "Liver - Hepatocytes, Lung - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" Receptor NA NA 7400000 "Cluster 47: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.2;Extravillous trophoblasts: 31.1;Muller glia cells: 84.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" FHIP1B "C11orf56, DKFZP566M1046, FAM160A2, FHIP, FLJ22665, KIAA1759" ENSG00000051009 "FHF complex subunit HOOK interacting protein 1B" Q8N612 11 6211345-6234711 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055994, HPA063987" Approved Approved Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 3 Mitochondria "HPA055994: AB_2682999, HPA063987: AB_2685166" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-2)" "unprognostic (9.59e-3)" "unprognostic (2.20e-2)" "unprognostic (1.51e-1)" "unprognostic (4.16e-2)" "unprognostic (2.64e-1)" "unprognostic (2.19e-1)" "unprognostic (5.02e-2)" "unprognostic (2.16e-1)" "unprognostic (8.04e-2)" "unprognostic (6.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (9.58e-2)" "unprognostic (1.85e-1)" FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 2 "Vesicles, Lipid droplets" "CAB017823: , HPA068859: AB_2686049" "prognostic unfavorable (5.91e-4)" "unprognostic (4.12e-2)" "prognostic favorable (8.42e-4)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.73e-4)" "unprognostic (7.06e-2)" "unprognostic (2.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.44e-3)" "unprognostic (4.22e-2)" "prognostic favorable (8.19e-4)" "unprognostic (1.48e-1)" "unprognostic (2.02e-1)" "unprognostic (5.45e-2)" "unprognostic (2.00e-2)" FIS1 "CGI-135, H_NH0132A01.6, TTC11" ENSG00000214253 "Fission, mitochondrial 1" Q9Y3D6 7 101239458-101252316 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 871.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017430 Approved Supported Mitochondria NA NA 140000 "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 22 Mitochondria "HPA017430: AB_1848608" "unprognostic (1.45e-2)" "unprognostic (8.20e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.48e-2)" "unprognostic (1.63e-1)" "unprognostic (7.73e-2)" "unprognostic (6.54e-2)" "unprognostic (5.33e-2)" "unprognostic (2.93e-1)" "unprognostic (1.36e-3)" "unprognostic (3.47e-2)" "prognostic favorable (1.08e-7)" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" FITM1 FIT1 ENSG00000139914 "Fat storage inducing transmembrane protein 1" A5D6W6 14 24130659-24132849 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 165.7;skeletal muscle: 216.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 273.2;Skeletal myocytes: 272.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019842 Uncertain NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA019842: AB_1853025" "unprognostic (1.81e-2)" "unprognostic (4.29e-7)" "unprognostic (2.77e-1)" "unprognostic (2.02e-3)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "prognostic favorable (1.00e-3)" "unprognostic (1.20e-4)" "unprognostic (4.57e-1)" "unprognostic (2.12e-2)" "unprognostic (2.84e-2)" "unprognostic (3.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.86e-2)" "unprognostic (5.62e-1)" "unprognostic (1.96e-1)" "unprognostic (2.12e-3)" FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 479.1" "Cell type enriched" "Detected in many" 5 "Plasma cells: 1382.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 357.0" "Breast - Plasma cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 170000 "Cluster 24: Non-specific - Transcription" "Cluster 15: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 1139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.8;granulocytes: 976.4;monocytes: 1017.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 29: Non-specific - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 57: Platelets - Hemostasis" 6 "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 1184.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 93.7;neutrophil: 78.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.7" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 10000 "Cluster 19: Eosinophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 32 Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 62: Hepatocytes - Metabolism" 1 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" FLRT1 "MGC21624, SPG68" ENSG00000126500 "Fibronectin leucine rich transmembrane protein 1" 11 64035931-64119173 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 8.5;Horizontal cells: 7.6;Inhibitory neurons: 15.3;Muller glia cells: 5.7;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 12.2;Schwann cells: 9.4" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Colon - Enteric glia cells, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054589 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA054589: AB_2682533" "unprognostic (5.13e-3)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (8.65e-2)" "unprognostic (2.89e-1)" "unprognostic (9.55e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (2.98e-1)" "unprognostic (4.64e-3)" "unprognostic (6.02e-2)" "unprognostic (1.79e-1)" "unprognostic (2.62e-2)" "unprognostic (5.62e-2)" "unprognostic (1.29e-3)" "unprognostic (4.37e-2)" FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 229.3;Alveolar cells type 2: 160.4;Basal prostatic cells: 69.4;Mesothelial cells: 71.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" "Developmental protein" NA NA 1100000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 1 "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 405.3" "Cell type enhanced" "Detected in many" "Adipocytes: 383.1;Endothelial cells: 364.4;Extravillous trophoblasts: 980.8;Microglial cells: 414.2;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.1;testis cancer: 39.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" Receptor NA NA 876000 87000 "Cluster 58: Placenta - Pregnancy" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 6 "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2;brain: 9.1;lymphoid tissue: 6.3" "Group enriched" "Detected in some" 5 "dendritic cells: 60.0;Inhibitory neurons: 57.5;Kupffer cells: 30.9;Langerhans cells: 21.1;Macrophages: 19.1;Schwann cells: 51.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 10.7" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.3" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Cancer enriched" "Detected in single" 67 "Leukemia: 28.4" "Prostate - Macrophages, Stomach - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" 3 "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Lymphatic endothelial cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 14 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" Receptor NA NA 20000000 290000000 "Cluster 1: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 2 "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" FLVCR1 "AXPC1, FLVCR, MFSD7B, PCA, SLC49A1" ENSG00000162769 "FLVCR heme transporter 1" Q9Y5Y0 1 212858275-212899363 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Erythrocyte maturation, Transport" Receptor "Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 48.3;Proximal enterocytes: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046646 Approved Approved "Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Small intestine - Absorption" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Cell Junctions" "HPA046646: AB_2679735" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.01e-1)" "unprognostic (2.83e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.03e-1)" "unprognostic (1.21e-1)" "unprognostic (3.88e-2)" "prognostic favorable (3.50e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.15e-2)" "unprognostic (2.25e-1)" "unprognostic (3.91e-2)" "unprognostic (7.29e-3)" FLVCR2 "C14orf58, CCT, FLJ20371, MFSD7C, SLC49A2" ENSG00000119686 "FLVCR heme transporter 2" Q9UPI3 14 75578620-75663214 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 29.3" "Cell type enhanced" "Detected in many" "Early spermatids: 73.3;Kupffer cells: 41.1;Late spermatids: 139.4;Microglial cells: 39.4;Proximal enterocytes: 41.4;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 14.1;intermediate monocyte: 14.6;myeloid DC: 7.6;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 7 "dendritic cells: 7.6;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037984 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA037984: AB_10672733" "unprognostic (2.42e-1)" "unprognostic (4.85e-2)" "unprognostic (4.19e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.44e-2)" "unprognostic (8.72e-2)" "unprognostic (2.78e-1)" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.53e-5)" "unprognostic (6.69e-2)" "unprognostic (9.94e-2)" "unprognostic (9.38e-2)" "unprognostic (1.16e-1)" FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 267.3;lymphoid tissue: 100.1" "Cell type enhanced" "Detected in many" "B-cells: 101.0;dendritic cells: 122.0;Langerhans cells: 176.6;Macrophages: 117.9;monocytes: 227.0;NK-cells: 188.5;Schwann cells: 90.0;T-cells: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Adrenocortical cancer: 84.6;Leukemia: 67.7;lymphoma: 77.0;Myeloma: 116.9" "Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 Cytosol "HPA008129: AB_1848963, HPA028288: AB_10612110" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (8.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (5.44e-2)" "unprognostic (6.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "prognostic unfavorable (4.23e-8)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.16e-1)" FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 191.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 27.7;Mesothelial cells: 59.0;Proximal enterocytes: 85.9;Proximal tubular cells: 165.1" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Kidney - Proximal tubular cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 5 "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" FMO2 ENSG00000094963 "Flavin containing dimethylaniline monoxygenase 2" Q99518 1 171185249-171212686 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.2;lung: 91.0" "Cell type enhanced" "Detected in many" "Adipocytes: 188.1;Alveolar cells type 1: 115.7;Breast myoepithelial cells: 84.3;Club cells: 74.4;Endothelial cells: 92.7;Fibroblasts: 115.3;Mucus glandular cells: 80.6;Salivary duct cells: 108.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Fibroblast_1, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028261 Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1088.9" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 406.5" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.1;Myeloma: 2.1" "Colon - Endothelial cells, Liver - Hepatocytes, Lung - Fibroblast_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 43: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 3 "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 46.8;liver: 59.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.5;Oligodendrocytes: 17.2;Proximal enterocytes: 15.9;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 662.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 94.5;Cholangiocytes: 122.1;Hepatocytes: 245.3;Intestinal goblet cells: 58.4;Proximal enterocytes: 93.4;Proximal tubular cells: 61.7" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" FMR1NB "CT37, FLJ25736, NY-SAR-35" ENSG00000176988 "FMR1 neighbor" Q8N0W7 X 147981337-148026665 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 332 "testis: 56.5" "Group enriched" "Detected in some" 24 "Spermatocytes: 558.3;Spermatogonia: 231.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bile duct cancer: 41.4;Myeloma: 11.8" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA011284, CAB026403" Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "CAB026403: , HPA011284: AB_1078898" "unprognostic (2.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (4.38e-2)" "unprognostic (4.11e-3)" "unprognostic (2.85e-1)" FNDC3A "bA203I16.5, FNDC3, KIAA0970" ENSG00000102531 "Fibronectin type III domain containing 3A" Q9Y2H6 13 48975912-49209779 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008927, HPA012555, HPA012825" Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" "Nucleoplasm, Golgi apparatus, Centrosome" Cytosol "HPA008927: AB_1078899, HPA012555: , HPA012825: AB_1848985" "unprognostic (1.54e-1)" "unprognostic (1.34e-3)" "unprognostic (8.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.91e-2)" "unprognostic (5.71e-2)" "unprognostic (6.17e-2)" "unprognostic (3.16e-2)" "unprognostic (1.87e-2)" "unprognostic (4.03e-2)" "prognostic favorable (4.25e-4)" "unprognostic (8.93e-3)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (6.14e-2)" FNDC3B "DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421" ENSG00000075420 "Fibronectin type III domain containing 3B" Q53EP0 3 172039578-172401669 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 260.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 37.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.9" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007859 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA007859: AB_1078900" "unprognostic (7.18e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (6.03e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (3.25e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (2.17e-3)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (3.50e-2)" "prognostic unfavorable (5.65e-7)" "unprognostic (4.35e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-2)" FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 120.3;liver: 123.8" "Cell type enhanced" "Detected in many" "Early spermatids: 183.9;Hepatocytes: 133.4;Late spermatids: 613.6" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 311.6;tongue: 459.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 52.9;Cardiomyocytes: 83.0;Horizontal cells: 44.1;Muller glia cells: 39.7;Serous glandular cells: 38.6;Skeletal myocytes: 45.9" "Group enriched" "Detected in many" 7 "glioma: 4.2;liver cancer: 10.0;testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 21.7;Sarcoma: 36.8" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" Hormone NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" "HPA051290: AB_2681422" "unprognostic (4.36e-2)" "unprognostic (9.08e-3)" "unprognostic (7.62e-4)" "unprognostic (1.03e-2)" "unprognostic (3.77e-2)" "unprognostic (6.26e-2)" "unprognostic (5.68e-2)" "unprognostic (2.76e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (3.15e-3)" "unprognostic (1.63e-1)" "unprognostic (9.07e-2)" "unprognostic (7.07e-3)" "unprognostic (1.13e-1)" "unprognostic (3.37e-3)" "unprognostic (1.33e-2)" FOCAD "FLJ20375, KIAA1797" ENSG00000188352 Focadhesin Q5VW36 9 20658309-20995955 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 35.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 511.8;Inhibitory neurons: 301.5;Oligodendrocyte precursor cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055015 Approved Uncertain Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 34: Neurons - Neuronal signaling" Mitochondria "HPA055015: AB_2682673" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.25e-4)" "unprognostic (3.69e-3)" "unprognostic (4.14e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.64e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (5.26e-2)" "unprognostic (9.15e-2)" "prognostic favorable (3.09e-8)" "unprognostic (1.90e-1)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (1.41e-2)" FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 259.0;prostate: 73.4" "Group enriched" "Detected in many" 13 "Oligodendrocytes: 342.1;Prostatic glandular cells: 547.4" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "prostate cancer: 262.4;Rhabdoid: 177.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Prostate glandular cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 40: Prostatic glandular cells - Transcription" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804115 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 187.7;lymphoid tissue: 158.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 206.7;Kupffer cells: 284.1;Macrophages: 169.6;monocytes: 857.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 4198.3" "Low cancer specificity" "Detected in some" "Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Skin - Macrophages" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 2 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" FPR2 "ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.6" "Cell type enriched" "Detected in some" 18 "monocytes: 793.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1191.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1191.9" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.8;Leukemia: 2.6;liver cancer: 2.1" "Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Neutrophils" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 5 "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.6" "Group enriched" "Detected in many" 10 "Excitatory neurons: 197.6;Inhibitory neurons: 362.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.5;thyroid gland: 4.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.3;Astrocytes: 43.7;Cholangiocytes: 15.3;Glandular and luminal cells: 42.3;Oligodendrocyte precursor cells: 14.6;Proximal tubular cells: 19.6;Skeletal myocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 27.3" "Lung - Alveolar cells type 2, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA028831 Uncertain Approved Cytosol NA NA 1500000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Glandular & Luminal cells - Unknown function" Cytosol "HPA028831: AB_10603668" "unprognostic (1.71e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-1)" "unprognostic (6.24e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.25e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.23e-7)" "unprognostic (7.21e-2)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (3.14e-1)" FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 82.1;skeletal muscle: 78.4;tongue: 71.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 93.1;Cardiomyocytes: 79.5;Cone photoreceptor cells: 107.0;Early spermatids: 107.6;Inhibitory neurons: 66.8;Late spermatids: 140.5;Oocytes: 105.9" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 57: Platelets - Hemostasis" 11 "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" FRRS1 "SDFR2, SDR2" ENSG00000156869 "Ferric chelate reductase 1" Q6ZNA5 1 99703970-99766635 "Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.5;Hepatocytes: 45.5;Syncytiotrophoblasts: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 12.4" "Cancer enriched" "Detected in all" 8 "Gallbladder cancer: 81.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017883 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA017883: AB_2294223" "unprognostic (3.97e-2)" "unprognostic (8.02e-2)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (8.54e-3)" "unprognostic (7.00e-2)" "unprognostic (2.64e-1)" "unprognostic (8.25e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (2.65e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (3.54e-2)" FRRS1L "C9orf4, CG-6" ENSG00000260230 "Ferric chelate reductase 1 like" Q9P0K9 9 109130293-109167249 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.8;Early spermatids: 35.6;Excitatory neurons: 88.5;Granulosa cells: 36.1;Horizontal cells: 123.4;Inhibitory neurons: 77.8" "Cancer enhanced" "Detected in some" "glioma: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071086 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA071086: AB_2686342" "unprognostic (7.44e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (2.21e-1)" "unprognostic (9.01e-2)" "unprognostic (3.10e-1)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (9.94e-2)" "unprognostic (1.51e-1)" "unprognostic (9.21e-4)" "unprognostic (7.35e-3)" "unprognostic (7.02e-2)" "unprognostic (5.78e-3)" "unprognostic (5.89e-2)" "unprognostic (2.85e-1)" "unprognostic (5.38e-3)" FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 42.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 249.8;Early spermatids: 93.7;Excitatory neurons: 76.3;Late spermatids: 84.6;Rod photoreceptor cells: 132.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: AB_10601324" "unprognostic (9.28e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (3.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.17e-5)" "unprognostic (4.20e-2)" "unprognostic (5.65e-2)" "unprognostic (9.64e-3)" "unprognostic (2.66e-3)" "unprognostic (3.32e-2)" "unprognostic (8.28e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.07e-2)" "unprognostic (1.22e-3)" FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 298.0;salivary gland: 214.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 100.4;Hepatocytes: 113.1;monocytes: 102.8;Serous glandular cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 75: Serous glandular cells - Salivary secretion" 4 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2;salivary gland: 64.3;stomach 1: 28.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.2;Gastric mucus-secreting cells: 69.0;Ionocytes: 145.1;Mucus glandular cells: 141.4;Proximal enterocytes: 187.9;Salivary duct cells: 110.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.9;Gastric cancer: 18.6" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "Plasma membrane" Cytosol "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851471 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 154.2;intestine: 70.3;retina: 79.6;salivary gland: 81.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.5;Ductal cells: 44.3;Enteroendocrine cells: 39.7;Intestinal goblet cells: 83.2;Ionocytes: 55.6;Paneth cells: 49.4;Proximal enterocytes: 79.6;Undifferentiated cells: 42.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" HPA046966 Supported NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543921-94549895 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Inflammatory response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 101.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 21.2;Intestinal goblet cells: 25.1;monocytes: 21.7" "Cancer enhanced" "Detected in all" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.2;Leukemia: 23.9" "Pancreas - Ductal cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "CAB000014: , CAB016129: AB_626918" "unprognostic (6.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.70e-3)" "unprognostic (2.46e-3)" "unprognostic (1.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (3.64e-4)" "unprognostic (7.26e-2)" "unprognostic (4.14e-1)" "unprognostic (4.81e-3)" "unprognostic (1.27e-1)" "unprognostic (9.08e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (3.10e-3)" FUT5 FUC-TV ENSG00000130383 "Fucosyltransferase 5" Q11128 19 5865826-5870540 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "Oocytes: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" HPA046966 Uncertain NA NA "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" "HPA046966: AB_2679879" "unprognostic (7.72e-2)" "unprognostic (3.59e-1)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.2;kidney: 35.1;salivary gland: 44.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.2;Intestinal goblet cells: 72.0;Ionocytes: 40.1;Paneth cells: 32.8;Proximal enterocytes: 118.6;Proximal tubular cells: 57.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;Gastric cancer: 4.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 51000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 948.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 15.6;NK-cells: 14.8;T-cells: 10.0" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA043410" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA043410: AB_2678467" "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.65e-3)" "unprognostic (2.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (2.00e-2)" "unprognostic (1.33e-3)" "unprognostic (8.09e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.6;stomach 1: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 736.3;Excitatory neurons: 321.8;Inhibitory neurons: 227.7;Oligodendrocyte precursor cells: 158.5;Oligodendrocytes: 209.1" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.8" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 3 Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 76.5" "Group enriched" "Detected in all" 21 "Early spermatids: 1080.5;Late spermatids: 2438.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 29: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 3 Cytosol "HPA041779: AB_10793974, HPA042196: AB_10797383" "unprognostic (2.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-2)" "unprognostic (4.36e-3)" "unprognostic (9.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.97e-2)" "unprognostic (1.06e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.50e-5)" "unprognostic (1.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1723.4;skeletal muscle: 1333.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 92.2;Leydig cells: 58.4;Muller glia cells: 59.2;Schwann cells: 243.2;Skeletal myocytes: 77.1;Smooth muscle cells: 59.0" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.1" "Group enriched" "Detected in many" 4 "B-cells: 11.1;T-cells: 6.9" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 6.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" FXYD2 "ATP1G1, HOMG2, MGC12372" ENSG00000137731 "FXYD domain containing ion transport regulator 2" P54710 11 117800844-117828698 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 3540.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1055.0;Distal tubular cells: 4293.6;Ductal cells: 1077.7;Proximal tubular cells: 4148.6" "Cancer enriched" "Detected in some" 8 "renal cancer: 49.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory CD8 T-cell: 14.8;naive CD4 T-cell: 5.1;naive CD8 T-cell: 4.4;NK-cell: 9.6;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;NK-cells: 9.6;T-cells: 14.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 220.9;Uterine cancer: 89.5" "Liver - Cholangiocyte, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "spinal cord: 30.5" "HPA064218, HPA068838" Supported Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" Mitochondria "HPA064218: AB_2685214, HPA068838: AB_2686047" "unprognostic (4.11e-4)" "unprognostic (1.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-3)" "unprognostic (1.09e-3)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.62e-1)" "unprognostic (4.01e-2)" "unprognostic (4.91e-2)" "unprognostic (1.24e-2)" "unprognostic (2.64e-1)" "prognostic favorable (3.23e-9)" "unprognostic (3.22e-3)" "unprognostic (4.38e-2)" "unprognostic (4.62e-1)" "unprognostic (3.00e-2)" FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115823-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1749.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 612.8;Distal enterocytes: 2942.0;Intestinal goblet cells: 871.0;Paneth cells: 1297.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1961.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 5.1" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" FXYD4 CHIF ENSG00000150201 "FXYD domain containing ion transport regulator 4" P59646 10 43371636-43376335 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "kidney: 288.8" "Cell type enriched" "Detected in some" 63 "Collecting duct cells: 3876.1" "Group enriched" "Detected in many" 5 "renal cancer: 10.7;urothelial cancer: 20.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "lung cancer: 3.0;testis cancer: 9.5" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058421 Enhanced Uncertain Cytosol NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol "HPA058421: AB_2683714" "unprognostic (2.92e-3)" "unprognostic (5.25e-1)" "unprognostic (9.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (5.17e-2)" "unprognostic (2.19e-1)" "unprognostic (6.12e-2)" "unprognostic (7.88e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-1)" "unprognostic (2.09e-2)" FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 544.4;granulocytes: 591.8;Hofbauer cells: 595.4;Langerhans cells: 530.8;monocytes: 536.6;T-cells: 464.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 191.6;Leydig cells: 235.3;Lymphatic endothelial cells: 294.4;Muller glia cells: 120.0;Ovarian stromal cells: 186.7;Peritubular cells: 348.5;Sertoli cells: 266.5" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 151.9" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 6: Ovarian stromal cells - Transcription" 44 "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" FXYD6-FXYD2 ENSG00000255245 "FXYD6-FXYD2 readthrough" 11 117820163-117876667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.3;salivary gland: 4.3" "Cell type enriched" "Detected in some" 9 "Distal tubular cells: 141.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068838, HPA075209" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear membrane, Vesicles" "HPA068838: AB_2686047, HPA075209: AB_2732285" FXYD7 ENSG00000221946 "FXYD domain containing ion transport regulator 7" P58549 19 35143250-35154302 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "brain: 314.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 40.6;Inhibitory neurons: 12.3;Microglial cells: 8.9;NK-cells: 13.0;T-cells: 19.2" "Cancer enhanced" "Detected in some" "glioma: 4.2;ovarian cancer: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 52.3" "Group enriched" "Detected in many" 23 "B-cells: 19.1;NK-cells: 52.3;T-cells: 23.8" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3;skin cancer: 5.4" "Thyroid - T-cells" "Low region specificity" "Detected in all" HPA026916 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA026916: AB_1849217" "unprognostic (1.25e-3)" "unprognostic (8.73e-3)" "unprognostic (4.64e-2)" "unprognostic (6.95e-4)" "unprognostic (8.47e-2)" "unprognostic (1.73e-2)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (1.90e-1)" "unprognostic (3.08e-2)" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (6.90e-5)" "unprognostic (1.51e-2)" "unprognostic (3.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" FZD10 CD350 ENSG00000111432 "Frizzled class receptor 10" Q9ULW2 12 130162459-130165740 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 16.3;skin 1: 9.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.1;Basal squamous epithelial cells: 15.1;Lymphatic endothelial cells: 6.4;Smooth muscle cells: 7.5;Squamous epithelial cells: 27.6;Suprabasal keratinocytes: 13.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.3;Esophageal cancer: 3.1" "Adipose subcutaneous - Smooth muscle cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "thalamus: 7.0" "Low region specificity" "Detected in many" "HPA014484, HPA014485" Uncertain Enhanced Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 6 Nucleoplasm "HPA014484: AB_1849132, HPA014485: AB_1849134" "unprognostic (2.41e-3)" "unprognostic (3.29e-1)" "unprognostic (4.74e-2)" "prognostic favorable (5.05e-7)" "unprognostic (2.81e-2)" "unprognostic (4.63e-2)" "unprognostic (8.62e-3)" "unprognostic (6.33e-2)" "unprognostic (5.41e-2)" "unprognostic (3.77e-2)" "unprognostic (2.70e-1)" "unprognostic (2.24e-3)" "unprognostic (2.66e-9)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.0;Leydig cells: 40.8;Peritubular cells: 35.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 21.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.7;Rod photoreceptor cells: 91.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 115.9" "Cell type enhanced" "Detected in many" "Adipocytes: 82.2;Basal prostatic cells: 29.7;Collecting duct cells: 27.2;Endothelial cells: 61.4;Fibroblasts: 32.6;Skeletal myocytes: 28.3;Smooth muscle cells: 27.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 22.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.8;Alveolar cells type 2: 61.9;Distal enterocytes: 99.0;Hepatocytes: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.4;Glandular and luminal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 28.0;Breast myoepithelial cells: 29.1;Cardiomyocytes: 23.4;Mucus glandular cells: 28.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 60.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 18 Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638247-35642296 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.9;Muller glia cells: 24.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 85.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 "Endoplasmic reticulum" "HPA045025: AB_10795888, HPA071142: AB_2686349" "unprognostic (1.20e-1)" "unprognostic (4.42e-3)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.21e-2)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "prognostic favorable (8.21e-4)" "unprognostic (4.92e-2)" "unprognostic (2.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.68e-1)" "unprognostic (7.34e-3)" "unprognostic (1.19e-1)" G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812911 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol NA NA 280000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 17 Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" G6PC1 "G6PC, G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit 1" P35575 17 42900797-42914438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 72.4;liver: 279.7" "Group enriched" "Detected in some" 8 "Hepatocytes: 231.1;Proximal enterocytes: 167.6" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "liver cancer: 1.7" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA052324 Enhanced NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 "HPA052324: AB_2681790" "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favorable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favorable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070620-44082151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 228.8" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Excitatory neurons: 56.7;Horizontal cells: 56.0;Inhibitory neurons: 65.2;Oligodendrocyte precursor cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050483, HPA058459" Uncertain Approved Centrosome "Intracellular and membrane" Receptor NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" 4 Centrosome "HPA050483: AB_2681140, HPA058459: " "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (2.93e-3)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (7.95e-4)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.54e-5)" "unprognostic (1.23e-3)" "prognostic unfavorable (3.77e-10)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.87e-2)" "unprognostic (2.55e-2)" GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 62.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 373.5;Inhibitory neurons: 377.6" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.9" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 65: Neurons - Synaptic function" 2 "CAB079065: , HPA013820: AB_1849364, HPA031684: AB_2673993" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 54.1;retina: 17.3" "Group enriched" "Detected in some" 6 "Bipolar cells: 169.6;Excitatory neurons: 213.3;Inhibitory neurons: 206.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.7" "Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: AB_2682904" "unprognostic (2.58e-2)" "unprognostic (4.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.31e-1)" "unprognostic (2.43e-1)" GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.6" "Group enriched" "Detected in many" 4 "Astrocytes: 403.5;Excitatory neurons: 151.0;Inhibitory neurons: 106.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.6" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 16.9;choroid plexus: 33.0;retina: 8.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 67.9;Hofbauer cells: 13.8;Inhibitory neurons: 21.3;Oligodendrocyte precursor cells: 54.7" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 113.2" "Group enriched" "Detected in some" 10 "Excitatory neurons: 26.6;Inhibitory neurons: 13.5" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079022: , HPA029363: , HPA077031: AB_2686825" "unprognostic (6.33e-2)" "unprognostic (8.94e-3)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (9.50e-3)" "unprognostic (2.57e-1)" "unprognostic (7.63e-2)" "unprognostic (8.50e-2)" "unprognostic (1.44e-2)" GABRA6 ENSG00000145863 "Gamma-aminobutyric acid type A receptor subunit alpha6" Q16445 5 161547063-161702593 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 281 "brain: 203.5" "Cell type enhanced" "Detected in single" "Cone photoreceptor cells: 1.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 150.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Region enriched" "Detected in some" 40 "cerebellum: 1073.9" "Region enriched" "Detected in some" 39 "cerebellum: 263.8" CAB022462 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "CAB022462: " "unprognostic (3.79e-2)" GABRB2 ENSG00000145864 "Gamma-aminobutyric acid type A receptor subunit beta2" P47870 5 161288429-161549044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 44.0" "Group enriched" "Detected in many" 20 "Excitatory neurons: 551.3;Inhibitory neurons: 748.3" "Cancer enriched" "Detected in some" 20 "thyroid cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.8" "Adipose subcutaneous - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001964, HPA067632" Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "CAB001964: , HPA067632: AB_2685874" "unprognostic (5.46e-2)" "unprognostic (1.03e-1)" "unprognostic (3.29e-1)" "unprognostic (2.26e-6)" "unprognostic (2.33e-2)" "unprognostic (6.65e-2)" "unprognostic (3.58e-2)" "unprognostic (1.82e-1)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (2.24e-4)" "unprognostic (1.22e-1)" "unprognostic (1.33e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-3)" "unprognostic (1.04e-2)" GABRD ENSG00000187730 "Gamma-aminobutyric acid type A receptor subunit delta" O14764 1 2019329-2030758 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 74 "brain: 259.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.4;Excitatory neurons: 29.0;Horizontal cells: 23.9;Inhibitory neurons: 36.0;Microglial cells: 8.1;Spermatogonia: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044371 Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" 3 "Golgi apparatus, Vesicles" "HPA044371: AB_2678916" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-8)" "unprognostic (6.34e-3)" "unprognostic (2.66e-3)" "unprognostic (1.04e-2)" "unprognostic (3.44e-3)" "unprognostic (2.14e-1)" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (4.12e-8)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.77e-1)" "unprognostic (5.16e-2)" GABRE ENSG00000102287 "Gamma-aminobutyric acid type A receptor subunit epsilon" P78334 X 151953124-151974680 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.3;brain: 13.8;heart muscle: 9.1" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 63.5;Syncytiotrophoblasts: 76.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 33.2;hypothalamus: 103.9;midbrain: 81.8;pons: 74.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Region enriched" "Detected in many" 4 "hypothalamus: 18.5" "Region enhanced" "Detected in many" "hypothalamus: 45.2" HPA045918 Uncertain NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA045918: AB_10961281" "unprognostic (1.33e-2)" "unprognostic (6.75e-2)" "unprognostic (3.50e-3)" "unprognostic (1.39e-3)" "unprognostic (2.43e-1)" "unprognostic (7.52e-2)" "unprognostic (5.06e-3)" "unprognostic (1.27e-1)" "unprognostic (3.58e-2)" "unprognostic (1.55e-1)" "unprognostic (6.44e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (4.05e-11)" "unprognostic (1.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (5.28e-2)" GABRG1 ENSG00000163285 "Gamma-aminobutyric acid type A receptor subunit gamma1" Q8N1C3 4 46035769-46124054 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 21.5" "Cell type enriched" "Detected in some" 4 "Astrocytes: 128.5" "Cancer enriched" "Detected in single" 8 "glioma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Adrenocortical cancer: 1.4;Myeloma: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035622, HPA058102" Approved Supported "Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 47: Astrocytes - Unknown function" 1 "Plasma membrane" "HPA035622: AB_10603669, HPA058102: " "unprognostic (2.50e-1)" "unprognostic (2.20e-1)" "unprognostic (6.06e-2)" "unprognostic (1.46e-2)" "unprognostic (7.39e-4)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" GABRG2 ENSG00000113327 "Gamma-aminobutyric acid type A receptor subunit gamma2" P18507 5 162000057-162162977 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 42.1;retina: 10.8" "Group enriched" "Detected in some" 9 "Bipolar cells: 110.3;Excitatory neurons: 232.1;Horizontal cells: 68.0;Inhibitory neurons: 160.7" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.6" "Group enriched" "Detected in many" 5 "B-cells: 1.6;granulocytes: 4.6;T-cells: 1.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 36.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079060 Supported NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "CAB079060: " "unprognostic (2.88e-2)" "unprognostic (1.56e-2)" "unprognostic (6.31e-3)" "unprognostic (3.07e-3)" "unprognostic (1.52e-1)" GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 26.3;testis: 9.0" "Group enriched" "Detected in some" 6 "Excitatory neurons: 428.9;Inhibitory neurons: 590.3;Late spermatids: 340.7;Muller glia cells: 158.8" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.1" "Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054010 Approved Approved "Nucleoli,Plasma membrane,Microtubules" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane, Microtubules" Nucleoli "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 147.3;esophagus: 166.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 158.2;Breast myoepithelial cells: 68.3;Club cells: 74.0;Fibroblasts: 73.7;Glandular and luminal cells: 480.2;Ionocytes: 128.1" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.8" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB014883 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.8;Melanocytes: 13.7;Microglial cells: 22.4;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cancer enhanced" "Detected in many" "skin cancer: 9.5" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 30: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 210.8;Late spermatids: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" Enzyme NA NA 53000 "Cluster 25: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 30: Granulocytes - Unknown function" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 210.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" Enzyme NA NA 2600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 21: Non-specific - Metabolism" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122340 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "choroid plexus: 822.8;kidney: 221.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 126.6;Inhibitory neurons: 125.2;Proximal tubular cells: 162.3" "Cancer enhanced" "Detected in all" "renal cancer: 30.9" "Region enriched" "Detected in all" 9 "choroid plexus: 878.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039330 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA039330: AB_10795249" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (4.98e-2)" "unprognostic (3.48e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.76e-1)" "unprognostic (9.10e-3)" "unprognostic (1.56e-3)" "unprognostic (1.38e-1)" "unprognostic (3.65e-1)" "unprognostic (3.82e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.24e-6)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (9.51e-2)" GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 27.9;Inhibitory neurons: 75.8;Oocytes: 17.6;Proximal enterocytes: 19.2;Proximal tubular cells: 34.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 45.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 123.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 27000 "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoplasm "HPA030138: AB_2673332" "unprognostic (5.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (2.82e-3)" "unprognostic (3.85e-2)" "unprognostic (2.10e-2)" "unprognostic (3.32e-1)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (5.18e-3)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (9.51e-3)" GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270877-11622005 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 141.8;Excitatory neurons: 100.9;Inhibitory neurons: 149.4;Microglial cells: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012955, HPA070681" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 300000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "Vesicles, Cytosol" "HPA012955: AB_1849460, HPA070681: " "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (7.37e-2)" "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (2.05e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-1)" "unprognostic (2.66e-3)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 75.3" "Cell type enhanced" "Detected in many" "Early spermatids: 172.5;Intestinal goblet cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 440000 "Cluster 32: Basophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329589 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 140.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 13.6;Excitatory neurons: 35.8;Horizontal cells: 17.0;Inhibitory neurons: 12.5;Mesothelial cells: 62.9" "Group enriched" "Detected in some" 5 "glioma: 0.9;ovarian cancer: 0.5;renal cancer: 1.6;thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 5.1" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA075016: AB_2686729" "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-3)" "unprognostic (2.85e-1)" "unprognostic (6.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" "unprognostic (5.69e-2)" GALNTL5 "GalNAc-T5L, GALNT15" ENSG00000106648 "Polypeptide N-acetylgalactosaminyltransferase like 5" Q7Z4T8 7 151956379-152019929 "Disease related genes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.5" "Group enriched" "Detected in some" 100 "Early spermatids: 365.8;Late spermatids: 574.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011140 Enhanced NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 11: Late spermatids - Unknown function" "HPA011140: AB_1078944" "unprognostic (2.33e-2)" "unprognostic (2.09e-1)" "unprognostic (1.55e-1)" GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;pituitary gland: 1.4" "Group enriched" "Detected in some" 4 "Early spermatids: 76.2;Oligodendrocyte precursor cells: 40.1" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 1.4" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in all" HPA074584 Supported "Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" GALR2 GALNR2 ENSG00000182687 "Galanin receptor 2" O43603 17 76074781-76077537 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 7.4" "Cell type enhanced" "Detected in some" "dendritic cells: 6.1;granulocytes: 3.7;Macrophages: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044513 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" "HPA044513: AB_10962510" "unprognostic (1.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-2)" "unprognostic (3.54e-1)" "unprognostic (3.49e-2)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-1)" "unprognostic (9.32e-5)" "unprognostic (2.31e-1)" "unprognostic (2.11e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (4.04e-2)" "unprognostic (8.14e-2)" GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 199.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.3;Endothelial cells: 84.9;Hofbauer cells: 68.6;Kupffer cells: 113.6;Macrophages: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.8;intermediate monocyte: 28.9;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 61.7" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Monocytes - Innate immune response" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "kidney: 48.6;liver: 165.5" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 56.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.0" "Cell type enriched" "Detected in many" 7 "Oocytes: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.5;testis cancer: 19.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Parietal cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 4 "basal ganglia: 61.2" "Low region specificity" "Detected in many" HPA026776 Approved Approved "Golgi apparatus" No No 750000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 44: Oocytes - Unknown function" "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 73.0;intestine: 138.1;salivary gland: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 105.0;Distal enterocytes: 215.7;Ductal cells: 97.2;Glandular and luminal cells: 76.4;Oocytes: 61.0;Proximal enterocytes: 86.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 16.4;pancreatic cancer: 29.8;stomach cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.0;pancreatic cancer: 51.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favorable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" GDAP1 "CMT2K, CMT4, CMT4A" ENSG00000104381 "Ganglioside induced differentiation associated protein 1" Q8TB36 8 74320613-74518007 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.3;Cone photoreceptor cells: 91.8;Excitatory neurons: 73.1;Horizontal cells: 62.3;Inhibitory neurons: 64.5;Oligodendrocyte precursor cells: 63.7;Rod photoreceptor cells: 85.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014266, HPA024334" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 29 Mitochondria Cytosol "HPA014266: AB_1849581, HPA024334: AB_1849583" "unprognostic (3.19e-2)" "unprognostic (1.52e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (3.31e-1)" "unprognostic (4.36e-2)" "unprognostic (1.72e-2)" "prognostic favorable (2.68e-4)" "unprognostic (3.88e-1)" "unprognostic (4.17e-1)" "unprognostic (9.44e-3)" "unprognostic (2.44e-1)" "unprognostic (5.40e-2)" "unprognostic (3.29e-1)" "unprognostic (6.99e-2)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.73e-1)" GDAP1L1 ENSG00000124194 "Ganglioside induced differentiation associated protein 1 like 1" Q96MZ0 20 44247099-44280947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 59.0;pituitary gland: 17.2" "Cell type enhanced" "Detected in some" "Early spermatids: 8.4;Excitatory neurons: 20.2;Horizontal cells: 17.6;Inhibitory neurons: 22.4;Late spermatids: 30.9;Oligodendrocyte precursor cells: 9.4" "Cancer enriched" "Detected in single" 14 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 14 "Neuroblastoma: 111.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054182, HPA063265" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA054182: , HPA063265: AB_2684972" "unprognostic (6.58e-3)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-4)" "unprognostic (3.69e-1)" "unprognostic (5.15e-1)" "unprognostic (6.45e-2)" "unprognostic (7.69e-2)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (4.74e-3)" "unprognostic (2.41e-1)" "unprognostic (3.81e-5)" "unprognostic (8.57e-2)" "unprognostic (1.87e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-1)" GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 353.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.3;Extravillous trophoblasts: 85.0;Late spermatids: 405.5;Proximal tubular cells: 100.1;Suprabasal keratinocytes: 102.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 20.8" "Breast - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 113.8;retina: 80.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.8;Cone photoreceptor cells: 112.1;Early spermatids: 39.8;Late spermatids: 167.8;Rod photoreceptor cells: 83.8;Syncytiotrophoblasts: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" GET1 "CHD5, WRB" ENSG00000182093 "Guided entry of tail-anchored proteins factor 1" O00258 21 39377698-39428528 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 139.3" "Cell type enhanced" "Detected in all" "Spermatocytes: 174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA018527 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" 27 "HPA018527: AB_1858860" "unprognostic (4.34e-3)" "unprognostic (3.28e-1)" "unprognostic (2.88e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (5.08e-2)" "unprognostic (6.86e-2)" "unprognostic (1.57e-3)" "unprognostic (8.74e-2)" "unprognostic (1.15e-2)" "unprognostic (4.02e-3)" "unprognostic (9.48e-2)" "unprognostic (6.50e-3)" "unprognostic (2.21e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-3)" "unprognostic (8.13e-2)" GET1-SH3BGR ENSG00000285815 "GET1-SH3BGR readthrough" 21 39380332-39515506 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.7;retina: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" HPA018527 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "HPA018527: AB_1858860" GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 196.8;Intestinal goblet cells: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 93000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favorable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 108.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 29.0;Fibroblasts: 70.3;Mesothelial cells: 129.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cancer enhanced" "Detected in many" "Brain cancer: 39.9" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" 1 Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116276803 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 38.4;Breast glandular cells: 27.1;Fibroblasts: 49.4;Hepatocytes: 34.4;Oligodendrocyte precursor cells: 85.4;Oocytes: 49.3;Schwann cells: 24.9" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 73.8" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 25.5;Late spermatids: 21.2;Melanocytes: 18.9;Oocytes: 32.3;Schwann cells: 117.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 14.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in all" 6 "spinal cord: 41.1" HPA020731 Approved Supported "Plasma membrane,Cytosol" NA NA 150000 "Cluster 45: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 "Plasma membrane" Cytosol "HPA020731: AB_1849635" "unprognostic (1.22e-1)" "unprognostic (6.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.47e-3)" "unprognostic (2.77e-3)" "unprognostic (1.27e-1)" "unprognostic (7.65e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-2)" "unprognostic (1.90e-5)" "unprognostic (2.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 15: Non-specific - Transcription" 1 "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561532 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 104.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 142.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 173.5;liver: 113.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 23.8;Ductal cells: 57.7;Exocrine glandular cells: 30.0;Proximal enterocytes: 49.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 119.6" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA 3600000 "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 52.3;intestine: 51.6;salivary gland: 54.2;skin 1: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 215.6;Intestinal goblet cells: 65.0;Paneth cells: 114.7;Proximal enterocytes: 128.6;Suprabasal keratinocytes: 65.1;Undifferentiated cells: 63.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 14.1;colorectal cancer: 19.1;Gallbladder cancer: 13.9" "Colon - Colon enterocytes, Liver - Cholangiocyte" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 6 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.9;Inhibitory neurons: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 75: Serous glandular cells - Salivary secretion" 8 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139482-84154841 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1011.6;Early spermatids: 958.2;Late spermatids: 2582.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" 7 Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 81.8;liver: 206.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.2;Hepatocytes: 119.8;Inhibitory neurons: 111.4;Oligodendrocyte precursor cells: 169.8;Syncytiotrophoblasts: 46.6" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" Receptor NA NA 2200000 24000000 "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 8: Neurons - Neuronal signaling" 9 "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.0" "Group enriched" "Detected in many" 5 "Adipocytes: 172.8;Endothelial cells: 129.8;Hofbauer cells: 43.6;Kupffer cells: 93.3;Lymphatic endothelial cells: 102.0;Macrophages: 45.1;monocytes: 82.6;NK-cells: 112.4;T-cells: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 17 "Leukemia: 3.6" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 40 "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" GIMAP1-GIMAP5 ENSG00000281887 "GIMAP1-GIMAP5 readthrough" 7 150716668-150743646 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "monocytes: 38.0;NK-cells: 69.8;T-cells: 101.5" "Cancer enriched" "Detected in single" 11 "Leukemia: 1.0" HPA053441 Supported "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Endoplasmic reticulum" "HPA053441: AB_2682152" GIMAP2 "DKFZp586D0824, HIMAP2, IAN12, IMAP2" ENSG00000106560 "GTPase, IMAP family member 2" Q9UG22 7 150685697-150693641 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 76.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 49.7;Kupffer cells: 107.8;Macrophages: 32.5;monocytes: 55.5;NK-cells: 56.2;T-cells: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 34.3" "Low region specificity" "Detected in some" "HPA013589, HPA014746" Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 "Lipid droplets" Nucleoplasm "HPA013589: AB_1849666, HPA014746: " "prognostic favorable (3.50e-4)" "unprognostic (4.73e-2)" "unprognostic (2.53e-1)" "unprognostic (3.56e-3)" "unprognostic (6.60e-2)" "unprognostic (6.64e-3)" "unprognostic (4.60e-2)" "unprognostic (5.97e-2)" "unprognostic (3.39e-2)" "unprognostic (3.91e-1)" "unprognostic (5.52e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.56e-2)" "unprognostic (3.08e-2)" GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 124.7" "Group enriched" "Detected in many" 4 "Adipocytes: 182.7;Endothelial cells: 224.2;Hofbauer cells: 118.3;Kupffer cells: 148.5;Lymphatic endothelial cells: 186.5;Macrophages: 108.2;NK-cells: 203.2;T-cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;pancreatic cancer: 9.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 19: NK-cells - Adaptive immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" GINM1 "C6orf72, dJ12G14.2" ENSG00000055211 "Glycosylated integral membrane protein 1" Q9NU53 6 149566294-149591748 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017210, HPA041679" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 35000 "Cluster 20: Non-specific - DNA binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 36: Late spermatids - Unknown function" 1 "Nucleoli fibrillar center, Plasma membrane" "HPA017210: AB_1845743, HPA041679: AB_2677611" "unprognostic (6.09e-3)" "unprognostic (2.19e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (7.24e-2)" "unprognostic (1.32e-3)" "unprognostic (3.18e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.64e-2)" "unprognostic (4.87e-2)" "unprognostic (4.79e-3)" GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.8;Enteroendocrine cells: 17.7;Gastric mucus-secreting cells: 34.2;Rod photoreceptor cells: 18.5" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 322.1;Astrocytes: 262.0;Basal keratinocytes: 173.2;Cardiomyocytes: 220.1;Endometrial stromal cells: 207.4;Lymphatic endothelial cells: 241.0;Suprabasal keratinocytes: 260.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 382.5;testis cancer: 417.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 6 "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" GJA10 CX62 ENSG00000135355 "Gap junction protein alpha 10" Q969M2 6 89894469-89921760 "Predicted membrane proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "Horizontal cells: 16.4" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA021145 Uncertain NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA021145: AB_2670600" "unprognostic (1.09e-1)" GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161052 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 7.5;parathyroid gland: 3.9;placenta: 2.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 15.9;Oocytes: 2.9;Sertoli cells: 5.4;Spermatogonia: 3.2" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.3;melanoma: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 5.7" "Kidney - Podocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA014821: AB_2669097" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.37e-2)" "unprognostic (2.58e-3)" "unprognostic (2.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.87e-3)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (7.52e-2)" "unprognostic (7.70e-2)" "unprognostic (4.02e-2)" "unprognostic (9.65e-8)" "unprognostic (2.87e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-2)" "unprognostic (8.04e-3)" GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 74.2;Endothelial cells: 62.5;Secretory cells: 151.5;Sertoli cells: 269.3;Smooth muscle cells: 241.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.0;ovarian cancer: 1.6" "Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047981 Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Smooth muscle cells - Signal transduction" 4 "HPA047981: AB_2680228" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.48e-1)" "unprognostic (5.24e-3)" "prognostic favorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (8.17e-2)" "unprognostic (6.83e-2)" "unprognostic (8.81e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.47e-2)" "unprognostic (3.74e-2)" "unprognostic (3.82e-3)" "unprognostic (7.96e-3)" GJA5 CX40 ENSG00000265107 "Gap junction protein alpha 5" P36382 1 147756199-147773362 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 35.4;placenta: 82.6" "Group enriched" "Detected in some" 9 "Cytotrophoblasts: 146.0;Extravillous trophoblasts: 376.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 23.9;breast cancer: 14.8" "Liver - Vascular Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB013080, HPA071370" Enhanced NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 27 "CAB013080: AB_2533263, HPA071370: " "unprognostic (1.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.22e-2)" "unprognostic (2.94e-2)" "unprognostic (3.88e-2)" "unprognostic (8.95e-2)" "unprognostic (1.23e-3)" "unprognostic (5.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (7.57e-2)" "unprognostic (1.97e-2)" "unprognostic (2.44e-1)" "unprognostic (4.41e-2)" "unprognostic (3.43e-2)" "unprognostic (8.93e-2)" GJA8 "CAE, CAE1, CX50, CZP1" ENSG00000121634 "Gap junction protein alpha 8" P48165 1 147902795-147909269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 5.7" "Group enriched" "Detected in some" 4 "Early spermatids: 18.5;Spermatocytes: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014715, HPA062940" Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 105 "HPA014715: AB_2732411, HPA062940: AB_2732693" "unprognostic (3.73e-2)" "unprognostic (2.35e-1)" GJA9 "CX58, CX59, GJA10" ENSG00000131233 "Gap junction protein alpha 9" P57773 1 38874069-38881587 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA067850 Uncertain NA NA "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "HPA067850: AB_2685910" "unprognostic (2.00e-1)" "unprognostic (8.78e-2)" "unprognostic (4.55e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-2)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-2)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (4.11e-3)" "unprognostic (2.32e-2)" GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 188.9;liver: 376.0;pancreas: 110.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 129.7;Distal enterocytes: 63.7;Exocrine glandular cells: 65.3;Hepatocytes: 261.0;Paneth cells: 62.7;Proximal enterocytes: 117.8;Undifferentiated cells: 62.9" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 43.3;skin cancer: 83.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 43: Hepatocytes - Metabolism" 37 "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 319.0;esophagus: 789.3;vagina: 504.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 230.2;Basal respiratory cells: 221.0;Basal squamous epithelial cells: 100.6;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 619.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Region enhanced" "Detected in many" "thalamus: 15.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 104.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 33 Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 75.6;skin 1: 140.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 98.9;Basal respiratory cells: 37.5;Basal squamous epithelial cells: 43.4;Squamous epithelial cells: 94.4;Suprabasal keratinocytes: 127.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 10 "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" GJB4 CX30.3 ENSG00000189433 "Gap junction protein beta 4" Q9NTQ9 1 34759740-34762327 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 42.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Basal prostatic cells: 3.7;Basal respiratory cells: 12.7;Ciliated cells: 3.0;Club cells: 6.5;Distal tubular cells: 3.1;Ionocytes: 6.6;Squamous epithelial cells: 3.2;Suprabasal keratinocytes: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.9;pancreatic cancer: 11.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055112, HPA073904" Enhanced Supported "Cell Junctions" NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 8 "Cell Junctions" "HPA055112: AB_2682699, HPA073904: " "unprognostic (3.30e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-2)" "unprognostic (2.18e-2)" "unprognostic (5.40e-2)" "unprognostic (3.65e-1)" "prognostic unfavorable (3.24e-5)" "unprognostic (3.73e-2)" "unprognostic (5.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.52e-4)" "unprognostic (5.42e-2)" GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 98.1;skin 1: 92.1;vagina: 33.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 54.7;Basal respiratory cells: 46.9;Basal squamous epithelial cells: 28.6;Squamous epithelial cells: 69.0;Suprabasal keratinocytes: 106.7" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 47.7;head and neck cancer: 51.5" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 32 "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 94.7;brain: 70.0;esophagus: 161.6;vagina: 99.7" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 349.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Group enriched" "Detected in many" 5 "Bladder cancer: 34.8;cervical cancer: 81.6;Esophageal cancer: 26.2;Gastric cancer: 21.1;head and neck cancer: 45.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 10 "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" GJB7 "bA136M9.1, CX25" ENSG00000164411 "Gap junction protein beta 7" Q6PEY0 6 87282980-87329278 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 6.8;pituitary gland: 5.4;placenta: 2.6" "Group enriched" "Detected in some" 4 "Ciliated cells: 10.7;Cytotrophoblasts: 10.7;Extravillous trophoblasts: 4.7;Horizontal cells: 3.8;Ionocytes: 5.5;Syncytiotrophoblasts: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.2" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA014392 Approved "Plasma membrane,Cytosol" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane, Cytosol" "HPA014392: " "unprognostic (8.30e-2)" "unprognostic (2.45e-1)" "unprognostic (3.06e-1)" "unprognostic (4.20e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-3)" "unprognostic (2.61e-1)" "unprognostic (5.13e-3)" "unprognostic (6.69e-3)" "unprognostic (1.59e-1)" "unprognostic (3.82e-2)" "unprognostic (4.15e-2)" "unprognostic (3.24e-1)" "unprognostic (5.64e-2)" "unprognostic (2.09e-2)" "unprognostic (3.10e-2)" GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 38.6;smooth muscle: 31.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.1;Sertoli cells: 73.4;Smooth muscle cells: 73.0;Spermatocytes: 17.3;Spermatogonia: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.9" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014005 Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum" "HPA014005: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 65.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.7;Lymphatic endothelial cells: 78.4;Oligodendrocytes: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.4;pancreas: 10.7;salivary gland: 11.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 40.1;Breast myoepithelial cells: 28.3;Mucus glandular cells: 13.9;Prostatic glandular cells: 24.5;Schwann cells: 24.9;Serous glandular cells: 29.7" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" GJD4 "CX40.1, FLJ90023" ENSG00000177291 "Gap junction protein delta 4" Q96KN9 10 35605341-35608935 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Paneth cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038266 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" "HPA038266: AB_10672741" "unprognostic (2.05e-1)" "unprognostic (2.58e-1)" "unprognostic (5.74e-6)" "unprognostic (2.00e-1)" "unprognostic (8.96e-2)" "unprognostic (3.92e-2)" "unprognostic (8.49e-2)" "unprognostic (7.70e-2)" "unprognostic (1.67e-2)" "unprognostic (2.44e-1)" "unprognostic (1.19e-10)" "unprognostic (3.06e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (1.31e-1)" GJE1 CX23 ENSG00000203733 "Gap junction protein epsilon 1" A6NN92 6 142132925-142135358 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014916 Uncertain NA NA "HPA014916: AB_1847134" GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731462 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 85.0;kidney: 101.6;liver: 69.4" "Cell type enhanced" "Detected in many" "Langerhans cells: 167.7;Macrophages: 115.5;monocytes: 392.2;Proximal enterocytes: 138.9;Proximal tubular cells: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 160.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 160.1" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA060687 Supported NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA060687: AB_2684343" "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favorable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" GK2 "GKP2, GKTA" ENSG00000196475 "Glycerol kinase 2" Q14410 4 79406361-79408228 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Glycerol metabolism, Spermatogenesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 870 "testis: 86.9" "Cell type enhanced" "Detected in some" "Early spermatids: 665.6;Late spermatids: 220.3;Spermatocytes: 159.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.1" HPA060687 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA060687: AB_2684343" "unprognostic (1.31e-1)" GK3P "GKP3, GKTB" ENSG00000229894 "Glycerol kinase 3 pseudogene" Q14409 4 165277807-165279704 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 12.7" "Group enriched" "Detected in some" 11 "Early spermatids: 99.6;Late spermatids: 32.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA060687 Uncertain NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Early spermatids - Unknown function" "HPA060687: AB_2684343" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "unprognostic (2.11e-2)" "unprognostic (3.94e-1)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (6.19e-2)" "unprognostic (6.99e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (4.56e-1)" "unprognostic (3.34e-4)" GLCCI1 "FAM117C, GIG18, TSSN1" ENSG00000106415 "Glucocorticoid induced 1" Q86VQ1 7 7968796-8094272 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 186.8;Inhibitory neurons: 143.1;Microglial cells: 107.4;Oligodendrocyte precursor cells: 259.4;Plasma cells: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 49.0" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001674, HPA005987" Approved Approved Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 Nucleoli "HPA001674: AB_1078971, HPA005987: AB_1078970" "unprognostic (6.12e-2)" "unprognostic (7.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.45e-1)" "unprognostic (6.17e-3)" "unprognostic (1.02e-2)" "unprognostic (4.40e-1)" "unprognostic (1.68e-3)" "unprognostic (3.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.17e-3)" "unprognostic (3.35e-1)" "unprognostic (9.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.56e-1)" "unprognostic (3.09e-1)" "unprognostic (9.20e-3)" GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 312.6;Extravillous trophoblasts: 473.6;Hofbauer cells: 307.5;Kupffer cells: 228.0;Langerhans cells: 487.0;Macrophages: 267.3;monocytes: 215.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" "No annotated function" NA NA 64000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" GLIPR1L2 MGC39497 ENSG00000180481 "GLIPR1 like 2" Q4G1C9 12 75391089-75432688 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 45.3" "Group enriched" "Detected in many" 12 "Early spermatids: 367.6;Spermatocytes: 266.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039795, HPA039866" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 31: Spermatocytes - Spermatogenesis" "Golgi apparatus" Vesicles "HPA039795: AB_10805595, HPA039866: AB_10795235" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.27e-1)" "unprognostic (7.74e-2)" "unprognostic (1.33e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "unprognostic (7.68e-3)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (5.91e-2)" "unprognostic (2.57e-2)" GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 177.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Lung - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 11.8;intestine: 13.0;urinary bladder: 11.4" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 26.6" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 17.9;liver cancer: 9.1;Rhabdoid: 8.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" GLRA1 STHE ENSG00000145888 "Glycine receptor alpha 1" P23415 5 151822513-151924851 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "retina: 2.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.0;Excitatory neurons: 1.7;Inhibitory neurons: 4.8;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Group enriched" "Detected in many" 5 "hypothalamus: 9.4;midbrain: 15.1;pons and medulla: 26.3" "Low region specificity" "Detected in all" "HPA078885, CAB079042" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" 2 "Vesicles, Plasma membrane" "CAB079042: , HPA078885: " "unprognostic (3.17e-1)" "unprognostic (2.47e-1)" "unprognostic (3.85e-7)" "unprognostic (8.24e-2)" "unprognostic (9.45e-3)" GLRA2 GLR ENSG00000101958 "Glycine receptor alpha 2" P23416 X 14529298-14731812 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 9.4;retina: 3.1" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 71.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070422, HPA078885" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "CAB070422: AB_11153055, HPA078885: " "unprognostic (2.52e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.90e-1)" "unprognostic (5.74e-2)" "unprognostic (1.81e-2)" "unprognostic (3.39e-1)" "unprognostic (5.82e-2)" "unprognostic (7.95e-3)" "unprognostic (1.13e-1)" "unprognostic (2.76e-1)" "unprognostic (6.69e-2)" GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;breast: 1.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.2;Early spermatids: 19.7;Excitatory neurons: 50.8;Horizontal cells: 13.2;Inhibitory neurons: 10.7;Late spermatids: 26.2" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078885 Approved "Vesicles,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "HPA078885: " "unprognostic (2.75e-3)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (9.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.64e-5)" "unprognostic (4.61e-4)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" GLRB ENSG00000109738 "Glycine receptor beta" P48167 4 157076125-157172090 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.7;parathyroid gland: 32.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 163.1;Inhibitory neurons: 106.2;Oligodendrocyte precursor cells: 103.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052363 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 61: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "HPA052363: AB_2681800" "unprognostic (7.36e-2)" "unprognostic (6.53e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-3)" "unprognostic (5.65e-2)" "unprognostic (1.18e-1)" "unprognostic (9.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-2)" "unprognostic (2.99e-2)" "unprognostic (6.81e-2)" "unprognostic (1.48e-1)" "prognostic favorable (4.89e-4)" "unprognostic (4.32e-3)" "unprognostic (1.85e-1)" "unprognostic (5.61e-2)" "unprognostic (1.66e-2)" GLT8D1 "AD-017, FLJ14611" ENSG00000016864 "Glycosyltransferase 8 domain containing 1" Q68CQ7 3 52694486-52706032 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 134.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008808, HPA010588" Approved Approved "Golgi apparatus,Centrosome" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Testis - Spermatid development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 50: Connective tissue cells - ECM organization" "Golgi apparatus" Centrosome "HPA008808: , HPA010588: AB_1078098" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.76e-4)" "unprognostic (3.17e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.82e-3)" "unprognostic (7.12e-2)" "unprognostic (9.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (5.82e-3)" "unprognostic (2.42e-3)" "unprognostic (3.97e-1)" "unprognostic (3.34e-2)" "unprognostic (6.21e-2)" GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 33: Non-specific - DNA binding" 3 Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 46.8;liver: 87.8;salivary gland: 53.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 62.7;Hepatocytes: 100.8;Intestinal goblet cells: 86.0;Serous glandular cells: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 12 Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 220.4;NK-cells: 203.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 160000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 19: NK-cells - Adaptive immune response" 6 "Golgi apparatus" "HPA014558: AB_2732409, HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favorable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67737118-67754388 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.1;Granulosa cells: 6.3;Inhibitory neurons: 1.2;Suprabasal keratinocytes: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013424 Enhanced NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA013424: AB_2668840" "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.78e-1)" "unprognostic (4.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.63e-1)" "unprognostic (9.03e-2)" "unprognostic (3.23e-2)" "unprognostic (9.67e-2)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" GOLGB1 "GCP, GCP372, giantin, GOLIM1" ENSG00000173230 "Golgin B1" Q14789 3 121663199-121749966 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011008, HPA011555" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" 2 "Golgi apparatus" "HPA011008: AB_1079011, HPA011555: AB_1079010" "unprognostic (2.56e-2)" "unprognostic (7.69e-2)" "unprognostic (1.46e-1)" "unprognostic (6.57e-2)" "unprognostic (5.34e-2)" "unprognostic (5.96e-2)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (6.58e-2)" "unprognostic (7.49e-2)" "unprognostic (3.65e-3)" "unprognostic (1.31e-1)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (9.90e-3)" "unprognostic (9.05e-2)" GOLIM4 "GIMPC, GOLPH4, GPP130, P138" ENSG00000173905 "Golgi integral membrane protein 4" O00461 3 168008689-168095924 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 228.5;Muller glia cells: 288.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001677, HPA002315" Enhanced Enhanced "Golgi apparatus" NA NA 1000000 "Cluster 29: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" "HPA001677: AB_1079017, HPA002315: AB_1079018" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (2.11e-1)" "unprognostic (4.76e-2)" "unprognostic (2.44e-1)" "unprognostic (5.17e-2)" "unprognostic (1.39e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.84e-3)" "unprognostic (9.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-3)" GOLT1B "CGI-141, GOT1, YMR292W" ENSG00000111711 "Golgi transport 1B" Q9Y3E0 12 21501781-21518408 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055909, HPA066383" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 8 Vesicles Nucleoplasm "HPA055909: AB_2682967, HPA066383: AB_2685667" "unprognostic (1.22e-2)" "unprognostic (3.07e-3)" "unprognostic (1.84e-1)" "unprognostic (3.65e-1)" "unprognostic (3.45e-1)" "unprognostic (5.37e-3)" "prognostic unfavorable (1.99e-8)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.83e-10)" "unprognostic (3.13e-1)" "unprognostic (2.14e-1)" "unprognostic (6.78e-2)" "unprognostic (1.04e-1)" GOSR1 "GOLIM2, GOS-28, GOS28, GS28, P28" ENSG00000108587 "Golgi SNAP receptor complex member 1" O95249 17 30477362-30527592 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020590 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" "HPA020590: AB_1850374" "unprognostic (1.54e-1)" "unprognostic (4.02e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (3.41e-1)" "unprognostic (2.83e-2)" "unprognostic (4.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-2)" "unprognostic (9.93e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.26e-4)" "unprognostic (8.64e-2)" "unprognostic (3.68e-1)" "unprognostic (7.56e-2)" "unprognostic (1.14e-2)" GOSR2 "Bos1, GS27" ENSG00000108433 "Golgi SNAP receptor complex member 2" O14653 17 46923075-46975524 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Congenital muscular dystrophy, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 271.6;Late spermatids: 1042.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017456, HPA048956, HPA054472" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" 45 "Nucleoplasm, Golgi apparatus" "CAB017456: AB_10532285, HPA048956: AB_2680569, HPA054472: AB_2682499" "unprognostic (3.28e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.30e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (7.43e-2)" "unprognostic (2.13e-1)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (2.41e-1)" "unprognostic (2.46e-3)" "unprognostic (4.50e-1)" "unprognostic (3.07e-1)" "unprognostic (2.84e-3)" "unprognostic (4.29e-2)" GP1BA "CD42b, GP1B, GPIbalpha" ENSG00000185245 "Glycoprotein Ib platelet subunit alpha" P07359 17 4932277-4935023 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;lymphoid tissue: 14.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Horizontal cells: 1.9;Langerhans cells: 2.7;Melanocytes: 1.7;Peritubular cells: 2.0;Rod photoreceptor cells: 1.9" "Cancer enhanced" "Detected in many" "testis cancer: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "basophil: 7.0" "Lineage enriched" "Detected in single" 44 "granulocytes: 7.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002496, HPA013316" Supported NA NA 1600000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 3 "CAB002496: AB_563748, HPA013316: AB_1855459" "unprognostic (4.87e-4)" "unprognostic (8.21e-2)" "unprognostic (2.81e-2)" "unprognostic (6.11e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-3)" "unprognostic (7.30e-3)" "unprognostic (5.58e-2)" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "unprognostic (6.54e-4)" "unprognostic (1.27e-1)" "unprognostic (4.85e-3)" "unprognostic (4.58e-3)" "unprognostic (2.56e-1)" "unprognostic (3.53e-4)" "unprognostic (8.35e-2)" GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 964 "pancreas: 34245.9" "Group enriched" "Detected in some" 7 "Cholangiocytes: 101.1;Exocrine glandular cells: 233.8;Prostatic glandular cells: 176.0" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.4" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "midbrain: 1.0" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" Receptor NA NA 41000 "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" GP5 CD42d ENSG00000178732 "Glycoprotein V platelet" P40197 3 194394821-194399266 "CD markers, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Leukemia: 1.2" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA072646 Approved Cytosol NA NA 270000000 "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: T-cells - T-cell receptor" 1 Cytosol "HPA072646: " "unprognostic (3.74e-2)" "unprognostic (3.40e-1)" "unprognostic (5.22e-2)" "unprognostic (2.96e-2)" "unprognostic (1.74e-2)" "unprognostic (1.35e-3)" "unprognostic (1.69e-3)" "unprognostic (1.68e-1)" "unprognostic (3.41e-1)" "unprognostic (2.80e-2)" "unprognostic (1.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (4.18e-2)" "unprognostic (3.14e-1)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;testis: 2.6" "Cell type enhanced" "Detected in some" "Early spermatids: 13.8;Excitatory neurons: 9.5;Horizontal cells: 4.4;Inhibitory neurons: 9.8;Late spermatids: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" "Blood coagulation" NA NA 44000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 2 "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lung: 3.1;lymphoid tissue: 8.7" "Group enriched" "Detected in some" 8 "Early spermatids: 8.3;Late spermatids: 20.6" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Group enriched" "Detected in some" 7 "basophil: 29.4;neutrophil: 14.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.4" "Cancer enriched" "Detected in single" 97 "Leukemia: 9.6" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 4 "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: AB_2684956" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.80e-2)" "unprognostic (2.50e-2)" "unprognostic (3.24e-1)" "unprognostic (2.53e-2)" "unprognostic (8.47e-2)" "unprognostic (8.70e-2)" GPA33 A33 ENSG00000143167 "Glycoprotein A33" Q99795 1 167052836-167166479 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 208.9" "Group enriched" "Detected in some" 4 "Distal enterocytes: 598.6;Intestinal goblet cells: 239.1;Paneth cells: 363.5;Proximal enterocytes: 220.5" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 84.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 24.3;T-reg: 19.6" "Lineage enriched" "Detected in many" 6 "T-cells: 24.3" "Cancer enhanced" "Detected in some" "Bile duct cancer: 34.1;colorectal cancer: 100.5" "Colon - Colon enterocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018858, CAB025943" Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 7 "CAB025943: , HPA018858: AB_1849909" "unprognostic (2.41e-2)" "unprognostic (1.71e-3)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (8.39e-4)" "unprognostic (1.55e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-2)" "unprognostic (9.63e-2)" "unprognostic (2.10e-2)" "unprognostic (9.44e-2)" "unprognostic (6.75e-2)" "unprognostic (5.22e-3)" "unprognostic (3.13e-1)" "unprognostic (9.68e-3)" "unprognostic (2.96e-3)" GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082337-144093149 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 3 "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (2.53e-3)" "unprognostic (1.39e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-2)" "unprognostic (2.49e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-3)" "unprognostic (2.64e-1)" "unprognostic (8.92e-2)" "unprognostic (1.67e-2)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 295.1;liver: 139.8" "Group enriched" "Detected in many" 5 "Astrocytes: 86.1;Hepatocytes: 147.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Adipocytes (Skin), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 3 Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 77.3;Sertoli cells: 32.6;Smooth muscle cells: 20.0;Spermatocytes: 74.5;Spermatogonia: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder cancer: 17.6" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 17: Breast glandular cells - Lactation" Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" GPAT3 "AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324" ENSG00000138678 "Glycerol-3-phosphate acyltransferase 3" Q53EU6 4 83535914-83605875 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 85.2" "Cell type enriched" "Detected in many" 9 "Langerhans cells: 1078.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 183.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029414 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" "HPA029414: AB_10601562" "unprognostic (9.51e-2)" "unprognostic (1.43e-2)" "unprognostic (5.67e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-3)" "unprognostic (2.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (2.92e-1)" "prognostic favorable (2.71e-9)" "unprognostic (3.74e-1)" "unprognostic (3.45e-2)" "unprognostic (2.53e-3)" "prognostic unfavorable (8.21e-4)" GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 115.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 17: Breast glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.9;breast: 17.3;gallbladder: 16.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.4;Enteroendocrine cells: 28.5;Hofbauer cells: 34.1;Kupffer cells: 34.5;Macrophages: 16.6;monocytes: 40.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 288.5;intermediate monocyte: 712.6;non-classical monocyte: 698.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.6" "Group enriched" "Detected in some" 5 "lymphoma: 2.0;Neuroblastoma: 2.2;Rhabdoid: 5.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA062890 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Monocytes - Innate immune response" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 219.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 382.6" "Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 9500000 "Cluster 21: Testis - Unknown function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133987100 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "placenta: 689.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.5;Extravillous trophoblasts: 70.0;Fibroblasts: 245.0;Muller glia cells: 70.0;Smooth muscle cells: 101.0;Syncytiotrophoblasts: 117.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.9;naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "Gastric cancer: 115.2;liver cancer: 376.5;Rhabdoid: 143.8;testis cancer: 249.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 50: Connective tissue cells - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.2;Astrocytes: 51.7;Extravillous trophoblasts: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 223.0" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 190000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 38.4" "Cell type enhanced" "Detected in many" "Adipocytes: 8.5;Distal enterocytes: 10.3;Hepatocytes: 22.9;Kupffer cells: 17.8;Muller glia cells: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.7;myeloid DC: 5.8" "Group enriched" "Detected in many" 23 "dendritic cells: 5.8;monocytes: 2.9" "Cancer enhanced" "Detected in many" "lymphoma: 11.1" "Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171, CAB080077, CAB080078, CAB080085" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to blood" Cytokine NA No 86000000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "Plasma membrane" "CAB018655: AB_2112653, CAB040563: , CAB080077: , CAB080078: , CAB080085: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" GPM6A GPM6 ENSG00000150625 "Glycoprotein M6A" P51674 4 175632934-176002664 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 635.9" "Cell type enhanced" "Detected in many" "Astrocytes: 3520.9;Excitatory neurons: 804.1;Inhibitory neurons: 556.0;Muller glia cells: 422.9;Oligodendrocyte precursor cells: 1258.9" "Cancer enriched" "Detected in many" 107 "glioma: 110.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 34.9;naive B-cell: 16.7" "Lineage enriched" "Detected in many" 12 "B-cells: 34.9" "Cancer enhanced" "Detected in many" "Brain cancer: 16.2;lymphoma: 10.7" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017338 Supported NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 5 "HPA017338: AB_1849933" "unprognostic (1.36e-4)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.34e-2)" "unprognostic (9.45e-2)" "unprognostic (1.34e-1)" "unprognostic (3.82e-5)" "unprognostic (2.24e-1)" "unprognostic (9.13e-3)" "unprognostic (1.06e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" "unprognostic (2.24e-2)" "unprognostic (3.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-3)" "unprognostic (2.60e-3)" GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "brain: 719.1;retina: 189.2" "Cell type enhanced" "Detected in many" "Astrocytes: 600.7;Melanocytes: 664.8;Muller glia cells: 1512.2;Oligodendrocyte precursor cells: 383.0;Oligodendrocytes: 1374.5;Schwann cells: 1005.8" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 230 "plasmacytoid DC: 78.2" "Lineage enriched" "Detected in single" 313 "dendritic cells: 78.2" "Group enriched" "Detected in many" 5 "Brain cancer: 36.3;Rhabdoid: 47.5;skin cancer: 77.9;testis cancer: 34.9" "Colon - Enteric glia cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 10: Muller glia cells - Visual perception" 1 "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" GPR101 ENSG00000165370 "G protein-coupled receptor 101" Q96P66 X 137023929-137033995 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "brain: 5.1" "Cell type enriched" "Detected in single" 4 "Plasma cells: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 26.4;hypothalamus: 30.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 38.3" "Low region specificity" "Detected in many" HPA001084 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 77: Plasma cells - Protein processing" 16 "HPA001084: AB_1078920" GPR107 "FLJ20998, KIAA1624, LUSTR1, RP11-88G17" ENSG00000148358 "G protein-coupled receptor 107" Q5VW38 9 130053426-130140169 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031704 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 37: Glandular & Luminal cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA031704: AB_10601018" "prognostic unfavorable (3.56e-5)" "unprognostic (7.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (8.72e-2)" "unprognostic (1.10e-3)" "unprognostic (1.35e-2)" "unprognostic (2.18e-1)" "unprognostic (3.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.85e-1)" "prognostic favorable (1.87e-5)" "unprognostic (4.10e-2)" "unprognostic (5.83e-2)" "unprognostic (6.50e-2)" "unprognostic (1.34e-3)" GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 "Golgi apparatus" Vesicles "HPA041924: AB_10804122, HPA041951: AB_10795385, HPA063863: AB_2685135" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "prognostic favorable (1.04e-7)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (4.23e-2)" "unprognostic (3.01e-2)" "unprognostic (7.89e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.29e-9)" "unprognostic (8.68e-3)" "unprognostic (2.95e-2)" "unprognostic (4.96e-3)" "unprognostic (4.13e-3)" GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;retina: 8.1;skin 1: 5.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.2;Hofbauer cells: 14.7;Horizontal cells: 22.7;Inhibitory neurons: 15.1;Salivary duct cells: 8.3;Secretory cells: 6.6" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;Rhabdoid: 2.4" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA050972: AB_2681295" "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 7.6" "Cell type enhanced" "Detected in some" "B-cells: 18.7;Langerhans cells: 60.0;Macrophages: 36.3;monocytes: 119.0;NK-cells: 18.7;T-cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 13.7;Myeloma: 7.9" "Adipose visceral - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages" "HPA029694, HPA029695" Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465380 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Early spermatids: 143.5;Late spermatids: 221.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045337 Uncertain NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" "HPA045337: AB_10960528" "unprognostic (1.55e-1)" "unprognostic (3.00e-1)" "unprognostic (6.09e-3)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (8.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-5)" "unprognostic (1.33e-2)" "unprognostic (1.90e-1)" "unprognostic (2.71e-2)" "unprognostic (2.68e-3)" GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 198.2" "Cell type enhanced" "Detected in all" "Early spermatids: 178.8;Late spermatids: 539.9;Spermatocytes: 144.1;Syncytiotrophoblasts: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" GPR137B TM7SF1 ENSG00000077585 "G protein-coupled receptor 137B" O60478 1 236142505-236221865 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 131.5" "Cell type enhanced" "Detected in many" "Langerhans cells: 152.8;Melanocytes: 103.1;Muller glia cells: 201.8;Rod photoreceptor cells: 157.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.6" "Group enriched" "Detected in many" 5 "granulocytes: 17.6;monocytes: 7.3" "Cancer enhanced" "Detected in all" "skin cancer: 69.0" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026422 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA026422: AB_1849338" "unprognostic (1.59e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (6.49e-2)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "unprognostic (5.54e-2)" "unprognostic (1.41e-1)" "unprognostic (5.06e-2)" "unprognostic (2.73e-2)" "unprognostic (5.53e-2)" "unprognostic (4.77e-2)" "unprognostic (2.83e-2)" "unprognostic (3.16e-1)" "unprognostic (7.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 29.9;epididymis: 7.6;retina: 16.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 82.5;Inhibitory neurons: 119.8;Oligodendrocyte precursor cells: 95.3;Oligodendrocytes: 127.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 15 "NK-cells: 1.5;T-cells: 1.4" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA003640: AB_2667025, HPA030763: AB_10602352" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (8.50e-3)" "unprognostic (7.34e-3)" "unprognostic (5.95e-3)" "unprognostic (2.32e-2)" "unprognostic (4.41e-2)" "unprognostic (8.42e-4)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.60e-1)" GPR139 PGR3 ENSG00000180269 "G protein-coupled receptor 139" Q6DWJ6 16 20028239-20073890 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046596 Uncertain NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA046596: AB_2679713" "unprognostic (2.94e-1)" GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367458-74372600 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "stomach 1: 1.7" "Cell type enriched" "Detected in single" 6 "Enteroendocrine cells: 1.1" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.0" "Cell type enriched" "Detected in many" 4 "Melanocytes: 190.7" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 74.2" "Adipose visceral - Mesothelial cells, Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003648 Enhanced NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Pancreas - Beta cells" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" GPR149 "IEDA, PGR10, R35" ENSG00000174948 "G protein-coupled receptor 149" Q86SP6 3 154334943-154430190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;seminal vesicle: 1.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 46.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.0" "Region enhanced" "Detected in many" "basal ganglia: 15.0" "Low region specificity" "Detected in many" HPA018020 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA018020: AB_1849334" GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531978-98534681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 30.3" "Group enriched" "Detected in some" 13 "B-cells: 8.7;Plasma cells: 33.8;T-cells: 22.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory B-cell: 3.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 5.1;T-reg: 12.2" "Group enriched" "Detected in many" 26 "B-cells: 3.6;T-cells: 12.2" "Cancer enhanced" "Detected in many" "lymphoma: 31.6" "Adipose visceral - T-cells, Breast - Plasma cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA013775 Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "HPA013775: AB_1849264" "unprognostic (8.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.72e-3)" "unprognostic (5.66e-2)" "unprognostic (9.48e-3)" "unprognostic (5.60e-5)" "unprognostic (5.17e-1)" "unprognostic (6.77e-3)" "unprognostic (3.96e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.83e-1)" "unprognostic (4.04e-3)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5;pancreas: 6.7" "Cell type enhanced" "Detected in some" "Early spermatids: 5.4;Extravillous trophoblasts: 5.9;Hofbauer cells: 2.9;Oocytes: 2.9;Sertoli cells: 2.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Macrophages, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" GPR151 "GALR4, PGR7" ENSG00000173250 "G protein-coupled receptor 151" Q8TDV0 5 146513144-146516190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Cone photoreceptor cells: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "midbrain: 17.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 19 "thalamus: 30.6" "Region enriched" "Detected in single" 9 "thalamus: 6.1" HPA065728 Supported NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 66: Photoreceptor cells - Visual perception" 35 "HPA065728: " "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-2)" GPR152 PGR5 ENSG00000175514 "G protein-coupled receptor 152" Q8TDT2 11 67451301-67452729 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035078 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" 163 "HPA035078: AB_10670286" "unprognostic (3.81e-2)" "unprognostic (1.69e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (3.76e-3)" GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.3;Horizontal cells: 46.6;Intestinal goblet cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 67.1;stomach 1: 51.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 115.5;Excitatory neurons: 96.0;Inhibitory neurons: 125.4;Melanocytes: 264.5;Oligodendrocyte precursor cells: 122.2;Schwann cells: 242.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 194.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Nuclear bodies, Cytosol" "HPA036159: AB_10671835, HPA057384: AB_2683424" "unprognostic (3.91e-2)" "unprognostic (7.93e-2)" "unprognostic (3.14e-2)" "unprognostic (4.11e-4)" "unprognostic (5.03e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (4.82e-2)" "unprognostic (2.59e-2)" "unprognostic (9.90e-2)" "unprognostic (1.82e-2)" "unprognostic (4.54e-2)" GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.6" "Group enriched" "Detected in some" 4 "Astrocytes: 14.2;Early spermatids: 8.1;Late spermatids: 19.6;Oligodendrocyte precursor cells: 12.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 39: Astrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.4" "Group enriched" "Detected in many" 4 "Langerhans cells: 315.3;Schwann cells: 117.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 23.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028697, HPA054948" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "Plasma membrane" "HPA028697: AB_10601810, HPA054948: " "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25174802-25602229 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.5;retina: 4.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 354.8;Horizontal cells: 65.5;Inhibitory neurons: 288.6;Oligodendrocyte precursor cells: 393.8;Oligodendrocytes: 94.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 10.9" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA013185: AB_2113957" "unprognostic (4.43e-2)" "unprognostic (3.14e-2)" "unprognostic (7.42e-2)" "unprognostic (2.66e-5)" "unprognostic (5.67e-2)" "unprognostic (9.37e-2)" "unprognostic (4.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.60e-6)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (3.90e-1)" GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8;parathyroid gland: 209.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 183.5;Paneth cells: 131.8;Proximal enterocytes: 348.1;Proximal tubular cells: 138.5;Undifferentiated cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079542-168137667 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 40.1;smooth muscle: 26.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.3;Horizontal cells: 44.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: Endometrial stromal cells - Transcription" 4 Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.1;choroid plexus: 75.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.3;Ciliated cells: 50.4;Excitatory neurons: 35.5;Horizontal cells: 71.8;Inhibitory neurons: 31.5;Muller glia cells: 46.1" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.5" "Group enriched" "Detected in many" 6 "granulocytes: 17.5;monocytes: 6.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.0" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;intestine: 23.0" "Cell type enriched" "Detected in some" 10 "Oligodendrocyte precursor cells: 54.7" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.5;lymphoid tissue: 20.7" "Cell type enriched" "Detected in some" 4 "T-cells: 125.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.6" "Lineage enriched" "Detected in many" 15 "T-cells: 110.6" "Group enriched" "Detected in some" 39 "Leukemia: 2.3;lymphoma: 6.0;Myeloma: 4.1" "Kidney - T-cells, Liver - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 27: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2;pituitary gland: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 41.2;Excitatory neurons: 19.0;Inhibitory neurons: 13.5;Oligodendrocyte precursor cells: 46.2;Oligodendrocytes: 39.4" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane, Cytosol" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavorable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favorable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.5" "Group enriched" "Detected in some" 5 "B-cells: 33.8;NK-cells: 36.7;T-cells: 76.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 11.2;lymphoma: 3.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041025, HPA058306" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799008-39920266 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 26.5;Excitatory neurons: 30.9;Inhibitory neurons: 54.5;Oligodendrocyte precursor cells: 38.2;Pancreatic endocrine cells: 18.7;Sertoli cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA039943: AB_10697711, HPA039979: AB_2676782" "unprognostic (4.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-2)" "unprognostic (1.38e-3)" "unprognostic (9.32e-2)" "unprognostic (3.23e-2)" "unprognostic (2.74e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (9.38e-7)" "prognostic unfavorable (6.84e-5)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (3.26e-2)" GPR179 "CSNB1E, GPR158L1" ENSG00000277399 "G protein-coupled receptor 179" 17 38324571-38343956 "Human disease related genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "retina: 13.4" "Cell type enriched" "Detected in some" 29 "Bipolar cells: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017885 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "HPA017885: AB_2279357" "unprognostic (1.65e-1)" "unprognostic (2.27e-1)" "unprognostic (1.24e-4)" "unprognostic (8.89e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.10e-1)" "unprognostic (3.04e-2)" "unprognostic (4.76e-2)" "unprognostic (2.34e-2)" "unprognostic (6.57e-3)" "unprognostic (5.31e-2)" "unprognostic (5.09e-10)" "unprognostic (6.18e-2)" "unprognostic (2.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.41e-4)" GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 9.6;lymphoid tissue: 38.0;testis: 12.7" "Group enriched" "Detected in some" 4 "Early spermatids: 94.1;Late spermatids: 239.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.5;NK-cells: 53.1;T-cells: 42.0" "Group enriched" "Detected in some" 17 "Leukemia: 6.7;lymphoma: 26.6" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013873 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 11: Late spermatids - Unknown function" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" GPR182 "ADMR, AM-R, G10D, hrhAMR" ENSG00000166856 "G protein-coupled receptor 182" O15218 12 56994492-56998447 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.6;testis: 5.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 194.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Sinusoid Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027037 Enhanced NA NA "Cluster 47: Spleen - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA027037: AB_1844622" "unprognostic (6.13e-2)" "unprognostic (6.23e-2)" "unprognostic (3.56e-2)" "unprognostic (5.88e-2)" "unprognostic (2.60e-2)" "unprognostic (3.30e-1)" "unprognostic (2.10e-4)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (4.94e-1)" "unprognostic (1.67e-2)" "unprognostic (8.13e-2)" "unprognostic (5.62e-3)" "unprognostic (9.31e-2)" "unprognostic (2.88e-2)" "unprognostic (1.42e-1)" "unprognostic (4.34e-3)" GPR183 EBI2 ENSG00000169508 "G protein-coupled receptor 183" P32249 13 99294539-99307399 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 111.2;lymphoid tissue: 82.2" "Cell type enhanced" "Detected in many" "dendritic cells: 4011.2;Langerhans cells: 3287.6;Macrophages: 936.4;monocytes: 866.8;Schwann cells: 952.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1054.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 14.9;lymphoma: 23.7;thyroid cancer: 22.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033690, HPA075590" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "CAB033690: AB_2114269, HPA075590: " "unprognostic (3.28e-3)" "prognostic favorable (9.77e-4)" "unprognostic (6.03e-2)" "unprognostic (4.61e-3)" "unprognostic (3.45e-1)" "unprognostic (7.11e-2)" "unprognostic (1.71e-1)" "unprognostic (6.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (2.33e-1)" "unprognostic (4.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.97e-3)" "unprognostic (9.31e-3)" "unprognostic (9.86e-3)" GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660890-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;pituitary gland: 7.6;testis: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 7.4;Early spermatids: 5.8;Excitatory neurons: 14.7;Inhibitory neurons: 14.9;Oligodendrocyte precursor cells: 14.6;Oligodendrocytes: 5.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.4" "Group enriched" "Detected in many" 15 "granulocytes: 2.9;T-cells: 6.4" "Cancer enhanced" "Detected in all" "testis cancer: 26.3" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA013955: AB_1849287" "unprognostic (1.92e-1)" "unprognostic (3.38e-2)" "unprognostic (1.72e-1)" "unprognostic (8.62e-5)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.67e-12)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (1.60e-1)" GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 13 "Sertoli cells: 27.2;Smooth muscle cells: 22.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Low cancer specificity" "Detected in single" "Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Testis - Endothelial cells, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" GPR21 ENSG00000188394 "G protein-coupled receptor 21" Q99679 9 123033667-123035665 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.6" "Cell type enhanced" "Detected in single" "Smooth muscle cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041651 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA041651: AB_10794673" "unprognostic (9.22e-3)" "unprognostic (1.46e-1)" GPR26 ENSG00000154478 "G protein-coupled receptor 26" Q8NDV2 10 123666355-123697399 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 2.8" "Group enriched" "Detected in some" 6 "Excitatory neurons: 11.0;Horizontal cells: 8.2" "Cancer enriched" "Detected in single" 13 "breast cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 81.5" HPA062736 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA062736: AB_2684855" "unprognostic (4.15e-2)" "unprognostic (5.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.12e-1)" "unprognostic (9.09e-2)" "unprognostic (9.98e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 8.7;Collecting duct cells: 9.7;Cone photoreceptor cells: 8.5;Glandular and luminal cells: 8.8;Granulosa cells: 15.8;Secretory cells: 9.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.3" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Neutrophils - Degranulation" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" GPR3 ACCA ENSG00000181773 "G protein-coupled receptor 3" P46089 1 27392622-27395814 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.2" "Cell type enhanced" "Detected in some" "Adipocytes: 5.4;Excitatory neurons: 2.5;Inhibitory neurons: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB006254 Uncertain NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB006254: AB_425462" "unprognostic (4.42e-2)" "unprognostic (2.22e-1)" "unprognostic (4.05e-2)" "unprognostic (1.55e-2)" "unprognostic (1.38e-2)" "unprognostic (1.27e-1)" "unprognostic (7.30e-3)" "unprognostic (6.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-1)" "unprognostic (5.94e-2)" "unprognostic (1.97e-1)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (1.03e-2)" GPR31 "12-HETER, HETER1" ENSG00000120436 "G protein-coupled receptor 31" O00270 6 167155247-167157980 "G-protein coupled receptors, Predicted membrane proteins" "Lipid metabolism" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 5 "Schwann cells: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014014, HPA027108" Uncertain NA NA "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA014014: AB_1849292, HPA027108: AB_10601474" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.42e-3)" "unprognostic (2.20e-3)" "unprognostic (5.95e-3)" "unprognostic (4.03e-2)" "unprognostic (3.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (8.10e-4)" "unprognostic (2.45e-1)" "unprognostic (6.01e-2)" GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 52.3;Hofbauer cells: 220.5;Kupffer cells: 135.2;Macrophages: 126.6;Microglial cells: 51.9" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 326.2;eosinophil: 113.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 326.2" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 109.1;retina: 37.9" "Group enriched" "Detected in many" 7 "Muller glia cells: 595.5;Oligodendrocytes: 302.4" "Group enriched" "Detected in many" 4 "glioma: 19.2;liver cancer: 5.7;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Approved "Nuclear membrane,Cytosol" No No 900000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 10: Muller glia cells - Visual perception" 17 "Nuclear membrane, Cytosol" "HPA042903: AB_2678219, HPA068009: AB_2685940" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.00e-5)" "unprognostic (6.19e-2)" "prognostic favorable (7.26e-4)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-2)" "unprognostic (6.12e-3)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-4)" GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122886-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 53.4" "Cell type enhanced" "Detected in some" "Astrocytes: 87.0;Muller glia cells: 55.9;Oligodendrocyte precursor cells: 83.5;Oligodendrocytes: 19.0;Schwann cells: 24.5" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 49 "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.4;Astrocytes: 11.5;Early spermatids: 19.7;Late spermatids: 19.6;Oligodendrocyte precursor cells: 17.5;Oocytes: 22.1;Spermatocytes: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.3" "Group enriched" "Detected in some" 6 "Adipocytes: 25.8;Endothelial cells: 33.1;Smooth muscle cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 1.8;prostate cancer: 2.2;Rhabdoid: 3.3;Sarcoma: 4.3;thyroid cancer: 4.1" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" GPR42 "FFAR3L, GPR41L, GPR42P" ENSG00000126251 "G protein-coupled receptor 42" O15529 19 35371068-35372962 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "granulocytes: 7.0;monocytes: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 30: Granulocytes - Unknown function" 88 "HPA044681: AB_2679043" "unprognostic (1.73e-3)" "unprognostic (1.31e-4)" GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Group enriched" "Detected in some" 24 "Early spermatids: 3.5;Late spermatids: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 2.0" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" "HPA055940: AB_2682977" "unprognostic (3.80e-3)" "unprognostic (5.92e-2)" "unprognostic (2.19e-3)" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.96e-1)" "unprognostic (1.61e-3)" "unprognostic (1.11e-2)" "unprognostic (3.13e-4)" "unprognostic (2.25e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "pituitary gland: 16.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 23.7" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 12 "hypothalamus: 6.6" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" 3 "Plasma membrane" Nucleoplasm "HPA049862: AB_2680920, HPA054678: AB_2682570" "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;pituitary gland: 2.6;retina: 2.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.0;Cone photoreceptor cells: 3.4;Excitatory neurons: 7.9;Horizontal cells: 8.8;Inhibitory neurons: 6.7;Schwann cells: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007326, HPA026088" Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 16 "HPA007326: AB_1849308, HPA026088: AB_10602323" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.51e-2)" "unprognostic (3.63e-3)" "unprognostic (2.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.46e-4)" "unprognostic (3.27e-1)" "unprognostic (4.08e-4)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (6.72e-2)" "unprognostic (3.85e-2)" GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 33.5;Excitatory neurons: 44.6;Inhibitory neurons: 19.3;Late spermatids: 30.3;Spermatocytes: 23.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 10.0" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 9.4" "Cell type enhanced" "Detected in many" "dendritic cells: 341.9;granulocytes: 495.1;NK-cells: 379.4;T-cells: 187.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 3.6;lymphoma: 7.1" "Skeletal muscle - Macrophages, Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 1.4;placenta: 2.9" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 20.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 5.1;testis cancer: 2.6" HPA013209 Uncertain NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA013209: AB_10601657" "unprognostic (6.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.17e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-2)" "unprognostic (3.70e-2)" "unprognostic (3.82e-4)" "unprognostic (6.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.88e-15)" "unprognostic (5.55e-3)" "unprognostic (3.93e-2)" "unprognostic (9.90e-3)" "unprognostic (8.15e-2)" GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 2.6;lymphoid tissue: 6.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.3;Horizontal cells: 15.1;Kupffer cells: 31.8;Macrophages: 15.6;Rod photoreceptor cells: 16.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 40.1;NK-cell: 10.8" "Group enriched" "Detected in many" 10 "granulocytes: 40.1;NK-cells: 10.8" "Not detected" "Not detected" "Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" GPR84 EX33 ENSG00000139572 "G protein-coupled receptor 84" Q9NQS5 12 54362445-54364487 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.5;urinary bladder: 15.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 28.2;Langerhans cells: 21.7;Macrophages: 32.1;monocytes: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 23 "basophil: 9.1;classical monocyte: 9.9;myeloid DC: 14.8;neutrophil: 6.0" "Group enriched" "Detected in many" 62 "dendritic cells: 14.8;granulocytes: 9.1;monocytes: 9.9" "Group enriched" "Detected in some" 6 "Leukemia: 3.9;lymphoma: 7.6" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" HPA027603 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" "HPA027603: AB_10612115" "unprognostic (5.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.36e-2)" "unprognostic (4.54e-2)" "unprognostic (6.16e-3)" "unprognostic (7.43e-2)" "unprognostic (9.29e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-2)" "unprognostic (2.92e-1)" "unprognostic (1.36e-9)" "unprognostic (1.27e-1)" "unprognostic (4.42e-2)" "unprognostic (1.40e-1)" "unprognostic (9.44e-2)" GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.9;skin 1: 31.8;vagina: 23.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 49.1;Basal respiratory cells: 141.2;Basal squamous epithelial cells: 48.5;Cytotrophoblasts: 57.4;Ionocytes: 60.0;Squamous epithelial cells: 50.7;Suprabasal keratinocytes: 64.2;Syncytiotrophoblasts: 217.7" "Group enriched" "Detected in many" 6 "cervical cancer: 44.1;head and neck cancer: 40.1;lung cancer: 22.0;urothelial cancer: 23.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.8;head and neck cancer: 95.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 27: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: AB_2685656" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (4.07e-3)" "unprognostic (8.60e-2)" "unprognostic (1.28e-2)" "unprognostic (4.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.62e-6)" "unprognostic (8.64e-2)" "unprognostic (1.50e-3)" "unprognostic (3.66e-4)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" GPR88 ENSG00000181656 "G protein-coupled receptor 88" Q9GZN0 1 100538139-100542021 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 78.8" "Cell type enriched" "Detected in some" 8 "Horizontal cells: 15.1" "Cancer enriched" "Detected in some" 9 "liver cancer: 12.0" "Region enriched" "Detected in all" 9 "basal ganglia: 200.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "basal ganglia: 719.1" "Region enriched" "Detected in many" 42 "basal ganglia: 358.6" HPA007488 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA007488: AB_2667844" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (8.37e-3)" "unprognostic (5.41e-1)" "unprognostic (5.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "unprognostic (7.76e-2)" "unprognostic (8.23e-3)" "unprognostic (2.45e-1)" "unprognostic (3.93e-4)" "unprognostic (1.85e-2)" "unprognostic (5.56e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-2)" GPR89A UNQ192 ENSG00000117262 "G protein-coupled receptor 89A" B7ZAQ6 1 145607988-145670650 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Endoplasmic reticulum" "HPA076096: AB_2686777" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.51e-3)" "unprognostic (4.51e-2)" "unprognostic (1.99e-3)" "unprognostic (8.14e-2)" "unprognostic (4.61e-3)" "unprognostic (5.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.00e-2)" "unprognostic (1.02e-5)" "unprognostic (1.42e-1)" "unprognostic (3.70e-2)" "unprognostic (5.47e-2)" "unprognostic (1.21e-1)" GPR89B "GPR89, GPR89C, SH120" ENSG00000188092 "G protein-coupled receptor 89B" P0CG08 1 147928393-147993592 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 31.1;Inhibitory neurons: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 1 "Endoplasmic reticulum" "HPA076096: AB_2686777" "unprognostic (7.78e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-2)" "unprognostic (1.37e-1)" "unprognostic (2.39e-2)" "unprognostic (1.15e-1)" "unprognostic (4.19e-3)" "unprognostic (1.05e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-4)" "unprognostic (1.23e-2)" "unprognostic (2.38e-2)" "unprognostic (1.61e-1)" "unprognostic (2.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.69e-1)" "unprognostic (7.15e-4)" GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 195.6;urinary bladder: 125.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1849.7;Alveolar cells type 2: 586.6;Club cells: 431.6;Distal enterocytes: 306.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 3.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 225.6" "Cell type enhanced" "Detected in many" "Early spermatids: 103.5;Late spermatids: 279.1;Lymphatic endothelial cells: 89.2;Oligodendrocytes: 159.1;Sertoli cells: 89.8" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Late spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 188.1;stomach 1: 224.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 139.7;Hepatocytes: 171.7;Ionocytes: 146.5;Paneth cells: 183.3;Secretory cells: 157.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940575-12952170 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 28.0" "Group enriched" "Detected in some" 4 "Early spermatids: 6.1;Gastric mucus-secreting cells: 4.1;Late spermatids: 6.5;Plasma cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "memory B-cell: 14.7;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 15 "B-cells: 14.7" "Cancer enriched" "Detected in many" 20 "Myeloma: 60.8" "Breast - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 13: Skin - Cornification" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" 24 "HPA071909: AB_2686470" "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 52.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 107.0;Oligodendrocyte precursor cells: 126.4;Oligodendrocytes: 118.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "eosinophil: 2.8;T-reg: 1.6" "Group enriched" "Detected in many" 8 "granulocytes: 2.8;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 19: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 53: Fibroblasts - ECM organization" 7 Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 18: Non-specific - Ribosome" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 14: Langerhans cells - Innate immune response" 1 "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 250.7;brain: 114.1;retina: 93.3" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Cone photoreceptor cells: 108.7;dendritic cells: 104.4;Excitatory neurons: 116.8;Inhibitory neurons: 98.5;Oligodendrocyte precursor cells: 89.1;Rod photoreceptor cells: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 6.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 6.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 69.7" "Kidney - Proximal tubular cells, Liver - Cholangiocyte" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" GRAMD1C DKFZp434C0328 ENSG00000178075 "GRAM domain containing 1C" Q8IYS0 3 113828182-113947174 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 172.5;Early spermatids: 113.3;Glandular and luminal cells: 56.9;Late spermatids: 78.7;Oligodendrocyte precursor cells: 77.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 2.7;naive B-cell: 3.0;neutrophil: 2.1" "Group enriched" "Detected in many" 13 "B-cells: 3.0;granulocytes: 2.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012316 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Plasma membrane, Cytosol" "HPA012316: AB_1849949" "unprognostic (2.73e-3)" "unprognostic (6.16e-3)" "unprognostic (3.27e-1)" "unprognostic (1.93e-1)" "unprognostic (5.50e-2)" "unprognostic (9.81e-3)" "unprognostic (1.43e-3)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (5.49e-2)" "prognostic favorable (4.22e-15)" "unprognostic (8.48e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-2)" "unprognostic (2.09e-2)" GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.0;placenta: 47.0" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 105.2;Syncytiotrophoblasts: 124.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 13.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 3 "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" GRAMD2B "FLJ21313, GRAMD3, NS3TP2" ENSG00000155324 "GRAM domain containing 2B" Q96HH9 5 126360132-126496494 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 422.7;Glandular and luminal cells: 158.9;Oligodendrocyte precursor cells: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.9;MAIT T-cell: 2.9;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.3;myeloid DC: 1.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 1.8;NK-cell: 1.1;plasmacytoid DC: 4.3;T-reg: 2.4" "Group enriched" "Detected in many" 6 "dendritic cells: 4.3;NK-cells: 1.1;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009678, HPA010095" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 10 Cytosol "Nucleoplasm, Golgi apparatus" "HPA009678: AB_2112580, HPA010095: AB_1849952" "unprognostic (2.34e-1)" "unprognostic (4.01e-1)" "unprognostic (4.63e-2)" "unprognostic (3.42e-2)" "unprognostic (6.82e-2)" "unprognostic (1.95e-2)" "unprognostic (6.76e-2)" "unprognostic (3.84e-2)" "unprognostic (9.90e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-2)" "unprognostic (3.78e-1)" "unprognostic (2.20e-3)" "unprognostic (3.56e-3)" "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "unprognostic (1.12e-2)" GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 269.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.0;Inhibitory neurons: 45.0;Ovarian stromal cells: 220.4;Peritubular cells: 51.8;Prostatic glandular cells: 187.5" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 38.4;Neuroblastoma: 28.9;skin cancer: 32.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" GRIA1 "GluA1, GLUR1, GLURA" ENSG00000155511 "Glutamate ionotropic receptor AMPA type subunit 1" P42261 5 153489615-153813869 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 54.9;retina: 30.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 311.1;Inhibitory neurons: 582.5" "Cancer enriched" "Detected in some" 15 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 6.7" "Lung - Fibroblast_1, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035202 Enhanced NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" 5 "HPA035202: AB_2674516" "unprognostic (2.51e-1)" "unprognostic (4.76e-3)" "unprognostic (1.97e-1)" "unprognostic (4.20e-2)" "unprognostic (6.95e-2)" "unprognostic (2.43e-1)" "unprognostic (2.61e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (2.35e-2)" "unprognostic (5.14e-4)" "unprognostic (7.97e-2)" "unprognostic (2.96e-2)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (2.80e-1)" "unprognostic (7.61e-2)" GRIA2 "GluA2, GLUR2, GLURB" ENSG00000120251 "Glutamate ionotropic receptor AMPA type subunit 2" P42262 4 157204182-157387146 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.6;pituitary gland: 21.1" "Cell type enhanced" "Detected in some" "Astrocytes: 317.7;Bipolar cells: 199.3;Excitatory neurons: 1054.4;Horizontal cells: 244.2;Inhibitory neurons: 693.4;Oligodendrocyte precursor cells: 1038.6;Oligodendrocytes: 302.3" "Group enriched" "Detected in some" 10 "breast cancer: 2.7;endometrial cancer: 2.6;glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4;Rhabdoid: 11.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008441 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA008441: AB_1078983" "unprognostic (1.36e-1)" "unprognostic (9.60e-3)" "unprognostic (4.15e-2)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (3.87e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-3)" "unprognostic (7.40e-2)" "unprognostic (2.91e-5)" "unprognostic (2.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (6.55e-2)" GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;retina: 16.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 452.9;Inhibitory neurons: 380.2;Oligodendrocyte precursor cells: 361.3" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.9;liver cancer: 4.0;Neuroblastoma: 3.0;thyroid cancer: 3.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" GRIA4 "GluA4, GLUR4, GLURD" ENSG00000152578 "Glutamate ionotropic receptor AMPA type subunit 4" P48058 11 105609535-105982090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 62.4;retina: 30.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 772.7;Horizontal cells: 237.3;Inhibitory neurons: 1002.4;Oligodendrocyte precursor cells: 708.9" "Cancer enriched" "Detected in some" 5 "glioma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 9.9;Rhabdoid: 9.5" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063282 Uncertain "Focal adhesion sites" "Intracellular and membrane" Receptor NA NA "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Focal adhesion sites" "HPA063282: " "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "unprognostic (4.09e-4)" "unprognostic (4.45e-3)" "unprognostic (1.92e-3)" "unprognostic (4.14e-4)" "unprognostic (1.40e-2)" "unprognostic (3.73e-4)" "unprognostic (1.62e-1)" "unprognostic (3.89e-1)" "unprognostic (2.04e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (1.38e-1)" "unprognostic (3.35e-2)" "unprognostic (1.28e-1)" GRID2 "GluD2, GluR-delta-2" ENSG00000152208 "Glutamate ionotropic receptor delta type subunit 2" O43424 4 92303966-93810157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.2;testis: 33.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 761.9;Inhibitory neurons: 935.9;Late spermatids: 715.2;Microglial cells: 365.0;Oligodendrocyte precursor cells: 2176.7;Oligodendrocytes: 422.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.8" "Region enhanced" "Detected in many" "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 99.3" "HPA056253, HPA058538" Enhanced NA NA "Cluster 78: Testis - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA056253: AB_2683079, HPA058538: AB_2683747" "unprognostic (2.78e-1)" "unprognostic (1.29e-4)" "unprognostic (7.23e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (3.50e-2)" "unprognostic (3.34e-1)" "unprognostic (6.92e-2)" "unprognostic (7.96e-3)" "unprognostic (4.36e-2)" "unprognostic (9.31e-2)" "unprognostic (7.38e-3)" GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 12.1;brain: 10.8;retina: 38.0" "Group enriched" "Detected in some" 12 "Inhibitory neurons: 2151.1;Oligodendrocyte precursor cells: 809.4" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 100962701-102081622 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 61.2" "Group enriched" "Detected in some" 26 "Excitatory neurons: 699.9;Inhibitory neurons: 2270.7;Oligodendrocyte precursor cells: 1157.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.2;skin cancer: 8.4" "Colon - Enteric glia cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" Receptor NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "CAB022463: , HPA014395: AB_1850303, HPA014623: AB_1850305" "unprognostic (1.43e-3)" "unprognostic (1.26e-2)" "unprognostic (3.99e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" "unprognostic (3.48e-2)" "unprognostic (2.57e-1)" "unprognostic (4.32e-2)" "unprognostic (8.46e-2)" "unprognostic (9.19e-2)" "unprognostic (4.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.34e-5)" "unprognostic (1.94e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-4)" GRIK4 "GluK4, GRIK, KA1" ENSG00000149403 "Glutamate ionotropic receptor kainate type subunit 4" Q16099 11 120511746-120988906 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6" "Cell type enhanced" "Detected in some" "Astrocytes: 78.6;Excitatory neurons: 111.7;Inhibitory neurons: 41.7;Oligodendrocyte precursor cells: 183.9;Oligodendrocytes: 100.8;Oocytes: 77.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 4.2" "Lung - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074453 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA074453: AB_2732255" "unprognostic (9.63e-2)" "unprognostic (4.96e-2)" "unprognostic (1.58e-1)" "unprognostic (2.49e-1)" "unprognostic (2.37e-1)" "unprognostic (6.64e-4)" "unprognostic (1.48e-2)" "unprognostic (7.26e-2)" "unprognostic (3.16e-1)" "unprognostic (2.38e-1)" "unprognostic (4.53e-2)" "unprognostic (2.50e-1)" "unprognostic (4.84e-11)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (4.47e-3)" "unprognostic (2.58e-2)" GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42070206 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;testis: 32.0" "Cell type enhanced" "Detected in some" "Astrocytes: 17.0;Bipolar cells: 20.1;Excitatory neurons: 31.3;Horizontal cells: 17.6;Inhibitory neurons: 29.8;Oligodendrocyte precursor cells: 29.7;Rod photoreceptor cells: 17.1" "Group enriched" "Detected in many" 5 "glioma: 15.4;ovarian cancer: 6.6;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.9;Neuroblastoma: 19.3" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 25: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA074001: AB_2732248" "unprognostic (4.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.30e-3)" "unprognostic (6.68e-3)" "unprognostic (4.28e-2)" "unprognostic (3.86e-1)" "unprognostic (5.82e-1)" "unprognostic (2.23e-1)" "unprognostic (3.89e-2)" "unprognostic (1.73e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.43e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (6.47e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-2)" "unprognostic (6.12e-2)" GRIN1 "GluN1, NMDAR1" ENSG00000176884 "Glutamate ionotropic receptor NMDA type subunit 1" Q05586 9 137138346-137168756 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "brain: 220.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 128.2;Horizontal cells: 125.3;Inhibitory neurons: 128.6" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.9;prostate cancer: 2.5" "Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067773 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "HPA067773: " "unprognostic (3.58e-2)" "unprognostic (4.51e-1)" "unprognostic (2.68e-2)" "unprognostic (5.48e-4)" "unprognostic (5.20e-2)" "unprognostic (1.25e-1)" "unprognostic (2.34e-2)" "unprognostic (2.81e-2)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (4.47e-2)" "unprognostic (1.44e-1)" "unprognostic (3.56e-3)" "unprognostic (4.72e-2)" GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 15.7" "Group enriched" "Detected in many" 13 "Excitatory neurons: 811.1;Inhibitory neurons: 864.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022725, HPA050216" Enhanced Uncertain "Endoplasmic reticulum,Vesicles" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 65: Neurons - Synaptic function" 1 "Endoplasmic reticulum" Vesicles "CAB022725: , HPA050216: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" GRIN2B "GluN2B, NMDAR2B" ENSG00000273079 "Glutamate ionotropic receptor NMDA type subunit 2B" Q13224 12 13437942-13982002 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "brain: 7.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 604.2;Inhibitory neurons: 845.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.5" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069762 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 65: Neurons - Synaptic function" 4 "HPA069762: AB_2686192" "unprognostic (2.01e-2)" "unprognostic (4.07e-2)" "unprognostic (7.89e-2)" "unprognostic (3.77e-3)" "unprognostic (3.39e-3)" "unprognostic (9.36e-2)" "unprognostic (5.92e-2)" "unprognostic (1.77e-2)" "unprognostic (6.85e-2)" "unprognostic (2.24e-1)" "unprognostic (4.68e-2)" "unprognostic (4.12e-2)" "unprognostic (4.48e-5)" "unprognostic (2.43e-1)" "unprognostic (8.76e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-1)" GRIN2D "EB11, GluN2D, NMDAR2D, NR2D" ENSG00000105464 "Glutamate ionotropic receptor NMDA type subunit 2D" O15399 19 48393668-48444931 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 35.0;Oligodendrocyte precursor cells: 14.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009006 Approved NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Neurons - Neuronal signaling" "CAB009006: AB_2279191" "unprognostic (9.96e-2)" "unprognostic (6.98e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-3)" "unprognostic (1.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.43e-4)" "unprognostic (7.84e-2)" "unprognostic (2.72e-1)" "unprognostic (2.23e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.66e-13)" "unprognostic (2.15e-2)" "unprognostic (1.92e-2)" "unprognostic (1.26e-3)" "unprognostic (1.14e-1)" GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 428.6;monocytes: 329.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 6 "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 17.0;retina: 5.4" "Group enriched" "Detected in some" 6 "Excitatory neurons: 208.5;Inhibitory neurons: 132.7;Rod photoreceptor cells: 125.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Neurons - Neuronal signaling" 1 Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Excitatory neurons: 15.6;Horizontal cells: 7.6;Rod photoreceptor cells: 3.5;Spermatocytes: 3.2" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 20 "HPA027868: , HPA065166: AB_2685425" "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" GRM4 "GPRC1D, mGlu4, MGLUR4" ENSG00000124493 "Glutamate metabotropic receptor 4" Q14833 6 34018643-34155622 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 331 "brain: 276.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.1;Horizontal cells: 19.5;Inhibitory neurons: 10.4;Late spermatids: 3.5;Spermatogonia: 4.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Region enriched" "Detected in all" 7 "cerebellum: 171.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in all" "cerebellum: 79.1" "Region enriched" "Detected in all" 5 "cerebellum: 178.6" CAB022096 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "CAB022096: " "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (7.00e-2)" "unprognostic (4.03e-2)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (3.56e-1)" "unprognostic (9.45e-2)" "unprognostic (2.08e-2)" "unprognostic (6.21e-3)" "unprognostic (2.44e-1)" "unprognostic (2.15e-11)" "unprognostic (5.32e-2)" "unprognostic (9.16e-2)" "unprognostic (6.57e-2)" "unprognostic (3.07e-1)" GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178977587-178996206 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "retina: 41.3" "Cell type enriched" "Detected in some" 35 "Bipolar cells: 482.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Brain cancer: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA014511: AB_2669025" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-1)" "unprognostic (2.25e-3)" "unprognostic (7.72e-2)" "unprognostic (2.32e-2)" "unprognostic (2.12e-3)" "unprognostic (6.27e-2)" "unprognostic (3.34e-4)" "unprognostic (2.58e-1)" "unprognostic (3.36e-4)" "unprognostic (1.23e-1)" "unprognostic (6.45e-2)" "unprognostic (7.59e-3)" "unprognostic (1.97e-1)" GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;parathyroid gland: 4.1" "Group enriched" "Detected in some" 15 "Excitatory neurons: 748.5;Inhibitory neurons: 568.5;Oligodendrocyte precursor cells: 1115.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253093 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "choroid plexus: 21.0" "Cell type enhanced" "Detected in some" "Early spermatids: 49.4;Excitatory neurons: 100.9;Inhibitory neurons: 128.7;Late spermatids: 76.3;Oligodendrocyte precursor cells: 30.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Region enriched" "Detected in all" 4 "choroid plexus: 103.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 6.5" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA051481: AB_2681499" "unprognostic (4.57e-3)" "unprognostic (5.10e-4)" "unprognostic (1.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.54e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (3.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" GRPR "BB2, BB2R, BRS2" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 19.6" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 6.0;Oocytes: 7.4" "Cancer enriched" "Detected in some" 4 "breast cancer: 6.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.1;Rhabdoid: 7.9" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "HPA069604: AB_2686158" "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" GSG1L "KTSR5831, MGC18079, PRO19651" ENSG00000169181 "GSG1 like" Q6UXU4 16 27787528-28063714 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 20.9;heart muscle: 22.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 25.1;Horizontal cells: 18.9;Oligodendrocyte precursor cells: 84.0" "Cancer enriched" "Detected in some" 7 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.9" "Colon - Colon enteroendocrine cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014479 Enhanced NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "HPA014479: AB_2247974" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "unprognostic (2.38e-1)" "unprognostic (7.06e-4)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" "unprognostic (2.05e-2)" "unprognostic (6.68e-2)" "unprognostic (5.02e-2)" "unprognostic (1.25e-1)" "unprognostic (2.50e-1)" "unprognostic (6.66e-2)" "unprognostic (1.55e-1)" "unprognostic (3.13e-1)" "unprognostic (6.35e-2)" "unprognostic (9.77e-2)" GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821321-120094994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 211.3;Inhibitory neurons: 235.9;Oligodendrocyte precursor cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006495, CAB016263, HPA028017" Approved Supported Nucleoplasm,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 15: Non-specific - Mixed function" 28 Nucleoplasm Cytosol "CAB016263: AB_2279451, HPA006495: , HPA028017: AB_10600708" "unprognostic (1.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.05e-3)" "unprognostic (6.79e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" GSTCD FLJ13273 ENSG00000138780 "Glutathione S-transferase C-terminal domain containing" Q8NEC7 4 105708778-105847725 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 116.4;Late spermatids: 68.3;Oligodendrocyte precursor cells: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046160, HPA061782" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Early spermatids - Spermatogenesis" 5 Nucleoplasm "HPA046160: AB_10961048, HPA061782: AB_2797265" "unprognostic (4.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.06e-3)" "unprognostic (4.44e-3)" "unprognostic (6.44e-2)" "unprognostic (6.43e-2)" "unprognostic (1.84e-3)" "unprognostic (4.30e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-2)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (8.59e-2)" "unprognostic (2.68e-1)" "unprognostic (1.32e-2)" "unprognostic (7.02e-2)" GTF3C1 TFIIIC220 ENSG00000077235 "General transcription factor IIIC subunit 1" Q12789 16 27459555-27549913 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 90.1;NK-cells: 119.6;Prostatic glandular cells: 98.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 32.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051617, HPA075900" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" 3 "Nucleoplasm, Nucleoli" "HPA051617: AB_2681553, HPA075900: " "unprognostic (6.46e-2)" "unprognostic (6.86e-3)" "unprognostic (2.16e-1)" "unprognostic (5.59e-2)" "unprognostic (6.65e-2)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (8.23e-2)" "unprognostic (9.25e-3)" "unprognostic (5.32e-2)" "prognostic favorable (9.56e-4)" "unprognostic (2.10e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.06e-1)" "unprognostic (5.67e-2)" "unprognostic (5.56e-3)" "unprognostic (8.23e-3)" GTF3C3 "TFIIIC102, TFiiiC2-102" ENSG00000119041 "General transcription factor IIIC subunit 3" Q9Y5Q9 2 196763035-196799725 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069179 Supported "Nucleoplasm,Nuclear membrane,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" 41 "Nucleoplasm, Nuclear membrane" "Nucleoli fibrillar center" "HPA069179: AB_2686099" "unprognostic (1.44e-1)" "unprognostic (2.63e-2)" "unprognostic (1.89e-1)" "unprognostic (4.52e-2)" "unprognostic (5.88e-2)" "unprognostic (3.64e-2)" "prognostic unfavorable (1.26e-6)" "unprognostic (1.92e-1)" "unprognostic (9.28e-2)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (5.62e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (2.72e-1)" "unprognostic (1.70e-1)" "unprognostic (3.08e-2)" GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 66.3" "Group enriched" "Detected in some" 10 "Distal enterocytes: 35.4;Enteroendocrine cells: 127.7;Intestinal goblet cells: 59.7;Paneth cells: 99.7;Proximal enterocytes: 70.4;Undifferentiated cells: 41.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Region enriched" "Detected in many" 4 "choroid plexus: 6.8" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Bile duct cancer: 10.5;colorectal cancer: 17.5;Gastric cancer: 7.2" "Colon - Colon enterocytes" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in many" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 80.5" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 109.7;Muller glia cells: 116.2;Syncytiotrophoblasts: 280.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA020587: AB_1850452" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (3.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (9.28e-2)" "unprognostic (8.25e-3)" "unprognostic (2.23e-1)" "prognostic favorable (4.25e-6)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.29e-1)" "unprognostic (7.33e-2)" "unprognostic (3.04e-4)" GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "bone marrow: 154.0" "Cell type enriched" "Detected in some" 308 "Erythroid cells: 1200.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Leukemia: 32.6" "Kidney - Proximal tubular cells, Liver - Erythroid cells, Lung - Neutrophil_1" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 15000000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 24 "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: AB_1849827" "unprognostic (1.60e-1)" "unprognostic (2.47e-2)" GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 434.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 1183.3;Hofbauer cells: 460.5;Lymphatic endothelial cells: 567.0" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 222.8;skin cancer: 319.3" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 56: Non-specific - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 1: Erythroid cells - Oxygen transport" 11 "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 15: Non-specific - Mixed function" 8 "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" HACD4 "Em:AL662879.1, PTPLAD2" ENSG00000188921 "3-hydroxyacyl-CoA dehydratase 4" Q5VWC8 9 20999509-21031640 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 58.2;Hofbauer cells: 85.2;Kupffer cells: 68.7;Langerhans cells: 70.6;Macrophages: 72.0;monocytes: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058666 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA058666: AB_2683793" "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (5.47e-2)" "unprognostic (1.70e-2)" "unprognostic (7.66e-2)" "unprognostic (1.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-4)" "prognostic favorable (3.14e-4)" "unprognostic (8.72e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.89e-3)" "unprognostic (7.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-3)" HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1158.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 51.0" "Lineage enriched" "Detected in all" 5 "T-cells: 51.0" "Cancer enhanced" "Detected in many" "Uterine cancer: 52.1" "Colon - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 48.0;ovary: 20.1" "Cell type enriched" "Detected in some" 4 "Mesothelial cells: 255.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Plasma membrane" Nucleoplasm "HPA067602: AB_2685871" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 21.9;urinary bladder: 19.7" "Cell type enhanced" "Detected in many" "Early spermatids: 23.2;Fibroblasts: 105.4;Langerhans cells: 32.5;Melanocytes: 34.4;Pancreatic endocrine cells: 90.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.5;urinary bladder: 89.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 119.4;Basal respiratory cells: 102.3;Squamous epithelial cells: 27.6;Suprabasal keratinocytes: 91.7" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 100.8;Gallbladder cancer: 185.3" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" HAVCR1 "CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1" ENSG00000113249 "Hepatitis A virus cellular receptor 1" Q96D42 5 157026742-157069396 "CD markers, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 4.5;kidney: 6.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;Inhibitory neurons: 1.3;Microglial cells: 5.4;Oligodendrocytes: 1.7;Proximal tubular cells: 2.6" "Cancer enriched" "Detected in many" 12 "renal cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 194.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA007173, CAB075697" Uncertain Approved Vesicles NA NA 155000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" Vesicles "CAB075697: , HPA007173: AB_1080282" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (6.99e-2)" "unprognostic (2.46e-3)" "unprognostic (4.75e-3)" "unprognostic (3.20e-2)" "unprognostic (3.21e-1)" "unprognostic (8.70e-4)" "unprognostic (3.81e-3)" "unprognostic (7.10e-3)" "prognostic unfavorable (7.81e-4)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "prognostic favorable (1.32e-4)" HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085422-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 53.6;Hofbauer cells: 144.9;Kupffer cells: 65.7;Langerhans cells: 77.2;Macrophages: 86.7;monocytes: 49.7;NK-cells: 134.1;Proximal tubular cells: 57.8;Schwann cells: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.2;intermediate monocyte: 62.7;myeloid DC: 118.8;NK-cell: 76.0;non-classical monocyte: 45.9" "Group enriched" "Detected in all" 6 "dendritic cells: 118.8;monocytes: 62.7;NK-cells: 76.0" "Cancer enhanced" "Detected in some" "lymphoma: 10.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 28: Dendritic cells - Antigen presentation" 3 "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" HBD ENSG00000223609 "Hemoglobin subunit delta" P02042 11 5232678-5243657 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "bone marrow: 2754.9" "Cell type enriched" "Detected in some" 522 "Erythroid cells: 8393.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 5.1" "Group enriched" "Detected in some" 5 "eosinophil: 2.1;neutrophil: 2.3;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 8 "dendritic cells: 1.6;granulocytes: 2.3" "Group enriched" "Detected in some" 15 "Leukemia: 20.4;Myeloma: 39.7" "Liver - Erythroid cells" "CAB037087, HPA043234" Supported NA NA 6600000000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 5 "CAB037087: AB_260051, HPA043234: AB_2678378" "unprognostic (1.32e-2)" "unprognostic (4.87e-2)" "unprognostic (4.14e-2)" "unprognostic (2.26e-3)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "unprognostic (1.04e-1)" "unprognostic (8.67e-2)" "unprognostic (2.83e-2)" "unprognostic (3.17e-1)" "unprognostic (6.24e-2)" "unprognostic (3.17e-1)" HBEGF "DTR, DTS, HEGFL" ENSG00000113070 "Heparin binding EGF like growth factor" Q99075 5 140332843-140346603 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 123.8" "Cell type enhanced" "Detected in many" "Macrophages: 223.9;monocytes: 315.2;Squamous epithelial cells: 297.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 1.6" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;monocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053243 Uncertain "Secreted to blood" "Growth factor" NA NA 118000 "Cluster 40: Monocytes - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 3 "HPA053243: AB_2682086" "unprognostic (3.64e-1)" "unprognostic (3.05e-1)" "unprognostic (4.31e-2)" "unprognostic (5.09e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (8.44e-3)" "unprognostic (3.51e-2)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (7.09e-4)" "prognostic favorable (6.00e-4)" "unprognostic (2.20e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" HBS1L "DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038" ENSG00000112339 "HBS1 like translational GTPase" Q9Y450 6 134960378-135103056 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis, Translation regulation" "Elongation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 184.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029728, HPA029729" Approved Approved "Nuclear bodies,Cytosol" NA NA 9200 "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 51: Oligodendrocytes - Unknown function" 1 "Nuclear bodies, Cytosol" "HPA029728: AB_10611112, HPA029729: AB_10601228" "unprognostic (3.68e-3)" "unprognostic (6.39e-2)" "prognostic favorable (6.77e-4)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.89e-2)" "unprognostic (8.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (7.73e-2)" "unprognostic (3.84e-1)" "unprognostic (4.98e-2)" "unprognostic (1.47e-1)" "unprognostic (4.20e-2)" HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.7;skin 1: 29.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 55.7;Basal prostatic cells: 154.4;Basal respiratory cells: 46.7;Basal squamous epithelial cells: 98.6;Langerhans cells: 141.4;Suprabasal keratinocytes: 65.7" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 12.1" "Immune cell enriched" "Detected in many" 5 "neutrophil: 177.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 177.3" "Cancer enhanced" "Detected in some" "Bladder cancer: 21.1;Esophageal cancer: 21.1;head and neck cancer: 40.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.1;esophagus: 16.3;lymphoid tissue: 19.2;skin 1: 16.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 78.8;Basal prostatic cells: 190.1;Basal respiratory cells: 53.3;Basal squamous epithelial cells: 138.3;Langerhans cells: 71.4;monocytes: 57.9;Squamous epithelial cells: 45.4;Suprabasal keratinocytes: 87.0" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebral cortex: 10.1" "Group enriched" "Detected in many" 6 "basophil: 58.8;neutrophil: 177.8;non-classical monocyte: 84.6" "Group enriched" "Detected in many" 50 "granulocytes: 177.8;monocytes: 84.6" "Cancer enhanced" "Detected in some" "Bladder cancer: 7.3;Gallbladder cancer: 6.8;head and neck cancer: 10.4" "Adipose visceral - Adipocytes (Visceral), Lung - NK-cells (Lung), Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" HCN1 "BCNG-1, BCNG1, HAC-2" ENSG00000164588 "Hyperpolarization activated cyclic nucleotide gated potassium channel 1" O60741 5 45254948-45696498 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 17.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 649.4;Inhibitory neurons: 735.4;Rod photoreceptor cells: 197.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Colon - Colon enteroendocrine cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019195 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" "HPA019195: AB_2670094" "unprognostic (1.30e-1)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (6.82e-2)" "unprognostic (1.10e-1)" "unprognostic (9.63e-3)" "unprognostic (4.11e-3)" "unprognostic (6.78e-2)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (3.68e-3)" HCN3 KIAA1535 ENSG00000143630 "Hyperpolarization activated cyclic nucleotide gated potassium channel 3" Q9P1Z3 1 155277463-155289848 "Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.7;liver: 14.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 6.0;Inhibitory neurons: 9.0" "Cancer enhanced" "Detected in all" "liver cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026584 Approved NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 69: Neurons - Neuronal signaling" "HPA026584: AB_1850534" "unprognostic (1.04e-1)" "unprognostic (6.22e-2)" "unprognostic (7.17e-2)" "unprognostic (1.34e-1)" "unprognostic (3.17e-1)" "unprognostic (1.48e-3)" "unprognostic (1.63e-1)" "unprognostic (5.97e-2)" "unprognostic (4.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.36e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (7.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.85e-1)" "unprognostic (5.90e-2)" "prognostic favorable (6.93e-4)" HCN4 ENSG00000138622 "Hyperpolarization activated cyclic nucleotide gated potassium channel 4" Q9Y3Q4 15 73319859-73368958 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 8.1;testis: 7.0" "Group enriched" "Detected in some" 4 "Early spermatids: 16.8;Late spermatids: 53.8" "Cancer enriched" "Detected in some" 4 "testis cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.8" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073174 Approved NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "HPA073174: " "unprognostic (2.21e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-2)" "unprognostic (3.14e-2)" "unprognostic (5.30e-3)" "unprognostic (1.92e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-2)" "unprognostic (2.37e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (6.05e-5)" "unprognostic (5.56e-2)" "unprognostic (4.60e-2)" "unprognostic (1.51e-2)" "unprognostic (7.95e-2)" HCRTR1 "ORXR1, OX1R, OXR1" ENSG00000121764 "Hypocretin receptor 1" O43613 1 31617686-31632518 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.1" "Cell type enriched" "Detected in single" 4 "Late spermatids: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014018 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 1 "HPA014018: AB_1854810" "unprognostic (2.96e-2)" "unprognostic (2.34e-2)" "unprognostic (7.86e-3)" "unprognostic (3.72e-3)" "unprognostic (2.42e-1)" "unprognostic (3.45e-3)" "unprognostic (2.54e-5)" "unprognostic (3.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (2.93e-1)" "unprognostic (3.77e-3)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" HCRTR2 "ORXR2, OX2R, OXR2" ENSG00000137252 "Hypocretin receptor 2" O43614 6 55106460-55282617 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.3;Inhibitory neurons: 17.6;Peritubular cells: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054516 Enhanced NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "HPA054516: AB_2682513" "unprognostic (4.86e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (7.45e-2)" "unprognostic (7.39e-2)" HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 249.9;lymphoid tissue: 112.9" "Group enriched" "Detected in many" 4 "dendritic cells: 350.0;Hofbauer cells: 690.6;Kupffer cells: 341.0;Langerhans cells: 714.2;Macrophages: 365.6;monocytes: 429.3;NK-cells: 1310.2;T-cells: 716.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Leukemia: 92.4;lymphoma: 51.9;Myeloma: 35.3" "Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB034435, HPA063026" Enhanced Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 2 "Golgi apparatus, Vesicles, Plasma membrane" "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019662, CAB045977" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 6 "Nucleoplasm, Cytosol" "CAB045977: AB_11124034, HPA019662: " "unprognostic (1.53e-1)" "prognostic favorable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favorable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavorable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" HEATR5A "C14orf125, DKFZP434I1735, p200b" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Oligodendrocyte precursor cells: 63.7;Oligodendrocytes: 89.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 121.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 121.1" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 49: Hindbrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" HECTD4 "C12orf51, FLJ34154, KIAA0614" ENSG00000173064 "HECT domain E3 ubiquitin protein ligase 4" 12 112160188-112382439 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 183.9;Inhibitory neurons: 172.4;Oligodendrocyte precursor cells: 102.4;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041062, HPA045473" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA041062: AB_2677281, HPA045473: AB_2679338" "unprognostic (9.27e-2)" "unprognostic (2.35e-1)" "unprognostic (6.50e-2)" "unprognostic (1.33e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (3.52e-2)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.95e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-2)" "unprognostic (2.81e-2)" "unprognostic (1.89e-1)" "unprognostic (1.58e-2)" "unprognostic (4.51e-3)" HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 251.5;Endothelial cells: 127.8;Mesothelial cells: 191.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "monocytes: 1.3;NK-cells: 2.1;T-cells: 1.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 510000000 "Cluster 33: Non-specific - ATP binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: AB_10601814" "unprognostic (3.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.56e-3)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "unprognostic (4.71e-2)" "unprognostic (5.85e-2)" "unprognostic (5.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 15.2;brain: 52.3;liver: 15.5" "Group enriched" "Detected in some" 8 "Astrocytes: 175.3;Oligodendrocyte precursor cells: 68.4;Oligodendrocytes: 151.9" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 93.2" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 122.9;Intestinal goblet cells: 451.9;Paneth cells: 363.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 10.1;lung cancer: 25.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 45: Intestine - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162671-66268867 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.8;smooth muscle: 53.0" "Cell type enhanced" "Detected in many" "Astrocytes: 74.0;Distal enterocytes: 148.7;Enteroendocrine cells: 48.9;Intestinal goblet cells: 106.1;Paneth cells: 67.8;Proximal enterocytes: 123.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.2;testis cancer: 40.2" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 45: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" HEPHL1 "DKFZp686F22190, Zp" ENSG00000181333 "Hephaestin like 1" Q6MZM0 11 94021354-94114208 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 4.4;lymphoid tissue: 9.3;skin 1: 3.7;vagina: 4.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 16.9;granulocytes: 4.9;Serous glandular cells: 22.1;Suprabasal keratinocytes: 6.7" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bladder cancer: 4.7;colorectal cancer: 4.4;head and neck cancer: 9.4" "Region enriched" "Detected in single" 12 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA031517 Uncertain NA NA 260000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA031517: AB_10603769" "unprognostic (9.16e-2)" "prognostic unfavorable (4.94e-4)" "unprognostic (2.40e-1)" "unprognostic (3.26e-6)" "unprognostic (3.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-2)" "unprognostic (6.71e-2)" "unprognostic (5.34e-1)" "unprognostic (1.09e-1)" "unprognostic (7.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 3 Cytosol "Plasma membrane" "CAB017188: , HPA048389: AB_2680382, HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favorable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 164.5;Oligodendrocyte precursor cells: 164.1;Oligodendrocytes: 194.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 147.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: AB_2686247" "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" HERC5 CEB1 ENSG00000138646 "HECT and RLD domain containing E3 ubiquitin protein ligase 5" Q9UII4 4 88457119-88506163 "Predicted membrane proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 56.2" "Group enriched" "Detected in many" 6 "Early spermatids: 115.8;Oocytes: 176.5;Spermatocytes: 313.2;Spermatogonia: 372.0" "Cancer enriched" "Detected in all" 5 "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA043929 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA043929: AB_10962492" "unprognostic (2.87e-1)" "unprognostic (2.10e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (4.46e-5)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.35e-1)" "unprognostic (2.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.23e-2)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (1.61e-1)" HERC6 FLJ20637 ENSG00000138642 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 6" Q8IVU3 4 88378739-88443097 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035846 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 59: Suprabasal keratinocytes - Cornification" Cytosol Nucleoplasm "HPA035846: AB_10673487" "unprognostic (1.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.23e-2)" "unprognostic (2.67e-2)" "unprognostic (8.61e-2)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (5.95e-2)" "unprognostic (1.52e-2)" "unprognostic (6.22e-2)" "prognostic favorable (7.14e-5)" "unprognostic (1.80e-1)" "unprognostic (2.59e-1)" "unprognostic (8.43e-3)" "unprognostic (3.77e-2)" HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 2218.2;Plasma cells: 2475.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 300.3" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" HERPUD2 FLJ22313 ENSG00000122557 "HERPUD family member 2" Q9BSE4 7 35632659-35697459 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 223.9;Late spermatids: 688.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015630, HPA076087" Approved Approved "Nucleoli,Nucleoli rim" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 15 "Nucleoli, Nucleoli rim" "HPA015630: AB_1850609, HPA076087: AB_2686774" "unprognostic (1.85e-2)" "unprognostic (5.31e-3)" "unprognostic (2.76e-1)" "unprognostic (3.79e-1)" "unprognostic (3.46e-1)" "unprognostic (2.73e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.30e-2)" "unprognostic (7.95e-2)" "unprognostic (5.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 53: Non-specific - Glycosylation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 58: Macrophages - Innate immune response" 2 "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 24.5;dendritic cells: 27.3;Excitatory neurons: 46.1;Oligodendrocytes: 24.2;Oocytes: 47.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" HHATL "C3orf3, GUP1, KIAA1173, MBOAT3, MSTP002, OACT3" ENSG00000010282 "Hedgehog acyltransferase like" Q9HCP6 3 42692663-42702824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 229.5;heart muscle: 502.6;skeletal muscle: 272.5;tongue: 148.2" "Group enriched" "Detected in some" 8 "Astrocytes: 56.0;Bipolar cells: 101.1;Cardiomyocytes: 154.3;Muller glia cells: 41.6;Oligodendrocytes: 156.4;Skeletal myocytes: 62.5" "Cancer enhanced" "Detected in many" "melanoma: 14.2;thyroid cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "thyroid cancer: 4.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018174 Enhanced NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" 13 "HPA018174: AB_2116671" "unprognostic (1.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.20e-2)" "unprognostic (9.71e-2)" "unprognostic (7.94e-3)" "unprognostic (3.79e-2)" "unprognostic (8.80e-2)" "unprognostic (2.47e-1)" "unprognostic (5.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (9.68e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-1)" "unprognostic (3.14e-1)" HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1;lung: 15.7" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 291.5;Leydig cells: 142.1;Oligodendrocytes: 384.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 115.1" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Uncertain Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296529-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 134.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 26.7;Distal enterocytes: 160.5;Exocrine glandular cells: 41.6;Proximal enterocytes: 171.7" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.4;Rhabdoid: 15.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 5: Enterocytes - Absorption" 13 "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" HIGD1A "DKFZP564K247, HIG1, RCF1A" ENSG00000181061 "HIG1 hypoxia inducible domain family member 1A" Q9Y241 3 42782908-42804490 "Predicted membrane proteins" "Electron transport, Respiratory chain, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 513.4;Distal enterocytes: 707.0;Distal tubular cells: 719.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 510.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043336 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" Mitochondria Nucleoplasm "HPA043336: AB_10795039" "unprognostic (6.46e-2)" "unprognostic (3.72e-3)" "prognostic favorable (2.12e-4)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (3.53e-1)" "unprognostic (3.70e-1)" "unprognostic (8.45e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-1)" "unprognostic (1.24e-1)" "unprognostic (8.94e-2)" "prognostic favorable (3.99e-8)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 101.0" "Cell type enhanced" "Detected in some" "Adipocytes: 77.5;Muller glia cells: 62.1;Sertoli cells: 301.9;Smooth muscle cells: 180.5" "Cancer enhanced" "Detected in all" "glioma: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 34: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (6.85e-2)" "unprognostic (9.41e-2)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-3)" "unprognostic (3.61e-1)" "unprognostic (1.18e-2)" "unprognostic (3.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-3)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.52e-2)" HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 39: Astrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" HIGD2B HIGD2BP ENSG00000175202 "HIG1 hypoxia inducible domain family member 2B" Q4VC39 15 72675798-72686182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.5" "Group enriched" "Detected in some" 19 "Early spermatids: 22.1;Late spermatids: 9.1;Spermatocytes: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA019016, HPA042715" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 63: Testis - Spermatid development" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 Mitochondria Cytosol "HPA019016: AB_1850711, HPA042715: AB_2678127" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.24e-3)" "unprognostic (5.09e-2)" "unprognostic (3.34e-1)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "unprognostic (1.39e-1)" "unprognostic (6.98e-2)" "unprognostic (3.90e-1)" "unprognostic (8.80e-2)" "unprognostic (6.11e-4)" "unprognostic (6.95e-2)" "unprognostic (2.97e-1)" "unprognostic (1.11e-2)" "unprognostic (3.18e-1)" HILPDA "C7orf68, FLJ21076, HIG-2, HIG2" ENSG00000135245 "Hypoxia inducible lipid droplet associated" Q9Y5L2 7 128455849-128458418 "Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 159.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 166.6;Cytotrophoblasts: 123.2;Extravillous trophoblasts: 286.5;Ionocytes: 180.0;Syncytiotrophoblasts: 327.1" "Cancer enhanced" "Detected in all" "renal cancer: 72.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 67.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010515 Approved Supported "Nucleoplasm,Lipid droplets" "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Lipid droplets" Nucleoplasm "HPA010515: AB_1850710" "unprognostic (1.10e-2)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (2.27e-1)" "unprognostic (2.10e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.30e-11)" "unprognostic (9.20e-3)" "unprognostic (4.07e-3)" "unprognostic (2.49e-1)" "unprognostic (4.06e-3)" "unprognostic (2.15e-2)" "prognostic unfavorable (2.05e-7)" "unprognostic (2.23e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929324-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 140.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Cytosol" Centrosome "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777998 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 155.1" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 431.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 27.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" 8 Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favorable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 203.7;monocytes: 210.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29949572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Ductal cells: 3710.2;Proximal enterocytes: 5253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - T-cells" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 4 "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31367067 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2389.7" "Cell type enhanced" "Detected in all" "monocytes: 4080.4;NK-cells: 5111.3;Proximal enterocytes: 4325.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid - T-cells" CAB015418 Enhanced NA NA 190000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 5 "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favorable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" HLA-DMA "D6S222E, RING6" ENSG00000204257 "Major histocompatibility complex, class II, DM alpha" P28067 6 32948613-32969094 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 117.5" "Cell type enhanced" "Detected in many" "B-cells: 408.7;dendritic cells: 484.6;Hofbauer cells: 446.2;Langerhans cells: 1619.3;Macrophages: 560.5;Schwann cells: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "classical monocyte: 3.8;intermediate monocyte: 3.8;memory B-cell: 6.4;myeloid DC: 7.2;naive B-cell: 6.4;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 12 "B-cells: 6.4;dendritic cells: 7.2;monocytes: 3.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.7;lymphoma: 15.5" "Adipose visceral - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012750, HPA017295" Enhanced Supported Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 4 Vesicles "HPA012750: AB_1853926, HPA017295: AB_2669575" "unprognostic (1.69e-3)" "unprognostic (3.52e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.64e-5)" "unprognostic (3.99e-1)" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.59e-4)" "unprognostic (7.01e-2)" "unprognostic (9.69e-2)" "unprognostic (6.66e-2)" "unprognostic (1.89e-1)" "unprognostic (2.12e-3)" "unprognostic (1.41e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-1)" "unprognostic (2.14e-2)" HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.6;lymphoid tissue: 99.1" "Cell type enhanced" "Detected in many" "B-cells: 242.4;dendritic cells: 307.0;Hofbauer cells: 312.7;Kupffer cells: 162.0;Langerhans cells: 576.8;Macrophages: 252.7;Proximal enterocytes: 278.8;Schwann cells: 142.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 129.1;dendritic cells: 85.5;monocytes: 73.9" "Cancer enhanced" "Detected in many" "lymphoma: 16.0;prostate cancer: 10.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Lung - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 47: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Vesicles "HPA012298: AB_1853927, HPA077524: " "unprognostic (5.34e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.89e-5)" "unprognostic (3.07e-1)" "unprognostic (7.64e-3)" "unprognostic (4.00e-1)" "unprognostic (3.46e-3)" "unprognostic (6.99e-2)" "unprognostic (8.76e-2)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (6.82e-3)" "unprognostic (2.03e-1)" "unprognostic (4.14e-2)" "unprognostic (8.35e-2)" "unprognostic (5.60e-2)" HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.0" "Cell type enhanced" "Detected in many" "B-cells: 62.8;dendritic cells: 54.0;Kupffer cells: 23.0;Langerhans cells: 77.2;Macrophages: 41.5;Schwann cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.1" "Group enriched" "Detected in many" 11 "B-cells: 21.1;dendritic cells: 17.8;monocytes: 6.0" "Cancer enhanced" "Detected in some" "lymphoma: 14.2" "Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 4.9" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA045038: AB_10959457, HPA076922: " "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (3.83e-2)" "unprognostic (2.60e-1)" "unprognostic (9.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.68e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" "unprognostic (9.95e-2)" "unprognostic (3.65e-2)" "unprognostic (8.70e-2)" "unprognostic (5.94e-2)" HLA-DOB ENSG00000241106 "Major histocompatibility complex, class II, DO beta" P13765 6 32812763-32820466 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 19.0;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in many" "B-cells: 94.4;Langerhans cells: 26.2;Plasma cells: 30.0;Schwann cells: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "memory B-cell: 214.6;naive B-cell: 259.2" "Lineage enriched" "Detected in many" 19 "B-cells: 259.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 17.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013846 Enhanced NA NA "Cluster 18: Non-specific - Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 1 "HPA013846: AB_1853928" "prognostic favorable (4.29e-4)" "unprognostic (3.84e-2)" "unprognostic (7.12e-3)" "unprognostic (6.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "unprognostic (4.48e-2)" "unprognostic (4.26e-3)" "unprognostic (6.95e-2)" "prognostic favorable (4.17e-5)" "unprognostic (2.37e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.15e-5)" "unprognostic (1.37e-1)" "unprognostic (1.64e-1)" "unprognostic (7.18e-2)" "unprognostic (2.46e-1)" HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 531.2;lymphoid tissue: 593.6" "Cell type enhanced" "Detected in many" "B-cells: 2146.0;dendritic cells: 1539.0;Langerhans cells: 8980.3;Macrophages: 2779.5;monocytes: 2073.0;Schwann cells: 6090.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 473.9;intermediate monocyte: 1069.2;memory B-cell: 818.4;myeloid DC: 1726.4;naive B-cell: 800.1;non-classical monocyte: 725.0;plasmacytoid DC: 542.7" "Group enriched" "Detected in all" 9 "B-cells: 818.4;dendritic cells: 1726.4;monocytes: 1069.2" "Cancer enhanced" "Detected in many" "lymphoma: 299.8;Myeloma: 115.4;skin cancer: 120.3" "Adipose visceral - T-cells, Testis - Macrophages, Thyroid - T-cells" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" HLA-DPB1 HLA-DP1B ENSG00000223865 "Major histocompatibility complex, class II, DP beta 1" P04440 6 33075990-33089696 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 270.1;lymphoid tissue: 399.6" "Cell type enhanced" "Detected in many" "B-cells: 2780.2;Langerhans cells: 13649.0;Macrophages: 2457.5;Schwann cells: 5697.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 286.9" "Group enriched" "Detected in all" 10 "B-cells: 229.7;dendritic cells: 286.9;monocytes: 138.3" "Group enriched" "Detected in some" 6 "Leukemia: 4.4;lymphoma: 14.2;skin cancer: 3.7" "Adipose visceral - T-cells, Testis - Macrophages, Thyroid - T-cells" "HPA011078, HPA058509" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA 470000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Cell Junctions" Nucleoplasm "HPA011078: AB_1079378, HPA058509: AB_2683737" "unprognostic (5.44e-3)" "unprognostic (7.03e-3)" "unprognostic (9.84e-2)" "prognostic favorable (3.38e-4)" "unprognostic (9.43e-2)" "unprognostic (1.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.51e-3)" "unprognostic (1.77e-2)" "unprognostic (5.64e-2)" "unprognostic (1.57e-1)" "unprognostic (4.34e-1)" "unprognostic (4.35e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (3.58e-2)" "unprognostic (1.85e-1)" HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 323.1;lymphoid tissue: 327.6" "Cell type enhanced" "Detected in many" "B-cells: 1044.9;dendritic cells: 627.3;Langerhans cells: 4525.8;Macrophages: 865.2;Schwann cells: 1859.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 667.5" "Group enriched" "Detected in all" 19 "B-cells: 288.5;dendritic cells: 667.5;monocytes: 257.5" "Cancer enhanced" "Detected in some" "lymphoma: 195.2;skin cancer: 49.0" "Adipose visceral - T-cells, Heart muscle - T-cells, Skin - Langerhans cells, Thyroid - T-cells" HPA012315 Enhanced NA NA 200000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 "HPA012315: AB_1853930" "unprognostic (4.24e-3)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (3.26e-1)" "unprognostic (5.81e-3)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" "unprognostic (6.74e-2)" "unprognostic (2.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.57e-1)" HLA-DQB1 "CELIAC1, HLA-DQB, IDDM1" ENSG00000179344 "Major histocompatibility complex, class II, DQ beta 1" 6 32659467-32668383 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 177.8;lymphoid tissue: 302.4" "Cell type enhanced" "Detected in many" "B-cells: 1196.0;dendritic cells: 876.0;Langerhans cells: 4977.2;Macrophages: 1143.6;Schwann cells: 2128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 149.8;intermediate monocyte: 141.0;memory B-cell: 161.5;myeloid DC: 392.1;naive B-cell: 171.4;plasmacytoid DC: 114.8" "Group enriched" "Detected in all" 6 "B-cells: 171.4;dendritic cells: 392.1;monocytes: 149.8" "Cancer enhanced" "Detected in many" "lymphoma: 101.7;skin cancer: 45.4" "Thyroid - T-cells" "Low region specificity" "Detected in all" HPA013667 Enhanced Supported "Golgi apparatus,Rods & Rings" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "Rods & Rings" "Golgi apparatus" "HPA013667: AB_1853932" "unprognostic (8.60e-3)" "unprognostic (1.91e-2)" "unprognostic (5.91e-2)" "unprognostic (9.85e-3)" "unprognostic (4.48e-1)" "unprognostic (5.30e-2)" "unprognostic (4.75e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-2)" "unprognostic (1.48e-1)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.34e-2)" "unprognostic (3.13e-1)" "unprognostic (4.16e-1)" "unprognostic (2.43e-1)" "unprognostic (1.40e-1)" HLA-DQB2 HLA-DXB ENSG00000232629 "Major histocompatibility complex, class II, DQ beta 2" P05538 6 32756098-32763532 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 50.8" "Group enriched" "Detected in some" 9 "Langerhans cells: 186.7;Macrophages: 50.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA073187 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA073187: " "prognostic favorable (5.55e-4)" "unprognostic (3.75e-3)" "unprognostic (2.16e-1)" "unprognostic (2.50e-2)" "unprognostic (2.10e-1)" "unprognostic (6.60e-2)" "unprognostic (8.15e-2)" "unprognostic (3.73e-3)" "unprognostic (6.48e-2)" "unprognostic (1.25e-1)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" "unprognostic (6.66e-2)" "unprognostic (1.23e-1)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (6.92e-2)" HLA-DRA HLA-DRA1 ENSG00000204287 "Major histocompatibility complex, class II, DR alpha" P01903 6 32439878-32445046 "Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 911.4;lymphoid tissue: 1247.6" "Cell type enhanced" "Detected in many" "B-cells: 6087.4;Langerhans cells: 28943.5;Macrophages: 6606.3;monocytes: 4953.5;Schwann cells: 10203.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 209.9;intermediate monocyte: 408.5;memory B-cell: 380.1;naive B-cell: 419.5;non-classical monocyte: 255.4;plasmacytoid DC: 231.2" "Group enriched" "Detected in all" 5 "B-cells: 419.5;dendritic cells: 231.2;monocytes: 408.5" "Group enriched" "Detected in many" 14 "Leukemia: 103.6;lymphoma: 328.5;Myeloma: 126.2;skin cancer: 86.9" "Adipose visceral - T-cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002798, CAB015402, HPA050162, HPA053176" Enhanced NA NA 950000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "CAB002798: , CAB015402: AB_629980, HPA050162: AB_2681037, HPA053176: AB_2682070" "unprognostic (1.20e-3)" "unprognostic (4.70e-3)" "prognostic favorable (5.30e-4)" "unprognostic (3.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-2)" "unprognostic (2.77e-2)" "unprognostic (3.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (1.98e-1)" "unprognostic (4.42e-2)" "unprognostic (5.67e-2)" "unprognostic (2.52e-2)" HLA-DRB1 HLA-DR1B ENSG00000196126 "Major histocompatibility complex, class II, DR beta 1" P01911 6 32577902-32589848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 563.4;lymphoid tissue: 597.1" "Cell type enhanced" "Detected in many" "B-cells: 2371.0;Langerhans cells: 11433.9;Macrophages: 3225.5;Schwann cells: 4924.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 655.8" "Group enriched" "Detected in all" 9 "B-cells: 209.8;dendritic cells: 655.8;monocytes: 313.1" "Cancer enhanced" "Detected in many" "lymphoma: 168.4;skin cancer: 100.3" "Thyroid - T-cells" "CAB015400, CAB034021, HPA043151" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 "CAB015400: AB_784538, CAB034021: AB_1124844, HPA043151: AB_2678342" "unprognostic (3.69e-3)" "unprognostic (3.66e-3)" "unprognostic (1.80e-2)" "unprognostic (2.40e-3)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (5.28e-2)" "unprognostic (1.22e-3)" "unprognostic (8.56e-2)" "unprognostic (3.00e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "unprognostic (2.28e-3)" "unprognostic (6.16e-2)" "unprognostic (1.19e-1)" "unprognostic (5.10e-2)" "unprognostic (1.53e-1)" HLA-DRB5 ENSG00000198502 "Major histocompatibility complex, class II, DR beta 5" Q30154 6 32517353-32530287 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 344.6;lymphoid tissue: 413.0" "Cell type enhanced" "Detected in many" "B-cells: 669.7;Langerhans cells: 2064.3;Macrophages: 825.9;Proximal enterocytes: 707.4;Schwann cells: 1302.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 62.3" "Group enriched" "Detected in all" 10 "B-cells: 26.2;dendritic cells: 62.3;monocytes: 35.2" "Cancer enhanced" "Detected in many" "lymphoma: 116.2;skin cancer: 63.3" HPA043151 Supported NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA043151: AB_2678342" "unprognostic (1.97e-3)" "unprognostic (4.74e-2)" "unprognostic (3.30e-2)" "prognostic favorable (7.89e-4)" "unprognostic (2.28e-2)" "unprognostic (4.68e-3)" "unprognostic (9.09e-3)" "unprognostic (2.08e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.87e-1)" "unprognostic (2.89e-2)" "unprognostic (1.45e-1)" "unprognostic (7.60e-3)" "unprognostic (9.72e-2)" "unprognostic (5.48e-2)" HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2275.7;Endothelial cells: 1508.4;monocytes: 2383.9;NK-cells: 1828.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "CAB024589, HPA031454, CAB080329" Enhanced Supported "Vesicles,Plasma membrane" "Secreted to blood" Immunity NA NA 100000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Vesicles, Plasma membrane" "CAB024589: AB_324025, CAB080329: , HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 13.1;placenta: 10.7" "Cell type enriched" "Detected in many" 21 "Extravillous trophoblasts: 2180.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Testis - Late spermatids" CAB016158 Enhanced "Secreted to blood" Immunity NA NA 32800000 67000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Lung - Lung function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 4 "CAB016158: AB_627938" "unprognostic (1.13e-2)" "unprognostic (9.95e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (2.51e-1)" "prognostic favorable (3.91e-5)" "unprognostic (6.34e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.19e-3)" HM13 "dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1" ENSG00000101294 "Histocompatibility minor 13" Q8TCT9 20 31514410-31577923 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 438.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045089, HPA056062" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Plasma cells - Protein processing" 4 "Endoplasmic reticulum" "HPA045089: AB_10962054, HPA056062: AB_2683022" "unprognostic (8.03e-2)" "unprognostic (2.11e-2)" "unprognostic (5.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.82e-1)" "unprognostic (5.87e-3)" "prognostic unfavorable (1.95e-5)" "unprognostic (2.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.10e-2)" "prognostic unfavorable (4.64e-12)" "unprognostic (3.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (8.17e-2)" HMGCR ENSG00000113161 "3-hydroxy-3-methylglutaryl-CoA reductase" P04035 5 75336329-75364001 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.6" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 233.0;Suprabasal keratinocytes: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008338, CAB016797, CAB078688" Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "CAB016797: , CAB078688: AB_2665607, HPA008338: AB_10960401" "unprognostic (5.07e-2)" "unprognostic (1.65e-2)" "unprognostic (3.65e-3)" "unprognostic (1.02e-2)" "unprognostic (1.65e-3)" "unprognostic (1.02e-1)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "unprognostic (1.90e-2)" "unprognostic (1.41e-1)" "unprognostic (3.99e-2)" "prognostic favorable (9.42e-6)" "unprognostic (2.44e-1)" "unprognostic (2.55e-2)" "unprognostic (3.64e-3)" "unprognostic (4.37e-2)" HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 597.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 313.8;Hofbauer cells: 507.7;Kupffer cells: 652.8;Macrophages: 508.8;Syncytiotrophoblasts: 642.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.9;intermediate monocyte: 239.0;non-classical monocyte: 331.0" "Lineage enriched" "Detected in all" 7 "monocytes: 331.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 25 "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 2013.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 44 "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.1;Langerhans cells: 1.4;Proximal enterocytes: 3.4;Spermatocytes: 3.4;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.8;breast cancer: 14.9" "Breast - Breast glandular cells (progenitors), Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "spinal cord: 1.4" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 65: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 195.1;liver: 845.2;pancreas: 264.2" "Group enriched" "Detected in many" 5 "Hepatocytes: 374.3;Proximal tubular cells: 162.4" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "liver cancer: 21.3;prostate cancer: 66.2" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "olfactory bulb: 3.1" HPA006804 Approved NA NA 3300000 "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 3 "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 73: B-cells - B-cell function" "Golgi apparatus, Plasma membrane" "HPA046281: AB_10961641, HPA052778: AB_2681943" "unprognostic (1.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.04e-4)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 31.6;Excitatory neurons: 33.5;Glandular and luminal cells: 39.2;Granulosa cells: 43.7;Secretory cells: 62.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Kupffer cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9;heart muscle: 25.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Excitatory neurons: 60.1;Hofbauer cells: 28.8;Kupffer cells: 38.0;Macrophages: 43.7;Oocytes: 23.5;Smooth muscle cells: 34.0" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 106.4;neutrophil: 141.7" "Group enriched" "Detected in many" 5 "granulocytes: 141.7;monocytes: 40.9" "Cancer enhanced" "Detected in some" "Leukemia: 7.1;Myeloma: 3.5;skin cancer: 3.7" "Liver - Neutrophils, Lung - Neutrophil_2, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "granulocytes: 5.1;Langerhans cells: 1.1;Melanocytes: 1.7;Spermatocytes: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.3" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Not detected" "Not detected" "Skin - Mast cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA035009 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" HRK DP5 ENSG00000135116 "Harakiri, BCL2 interacting protein" O00198 12 116856144-116881441 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.9;choroid plexus: 3.3;lymphoid tissue: 3.4;pituitary gland: 2.7;thyroid gland: 3.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 11.3;Cone photoreceptor cells: 8.5;Excitatory neurons: 9.2;Late spermatids: 8.0;Paneth cells: 7.8;Sertoli cells: 13.6" "Cancer enhanced" "Detected in many" "melanoma: 2.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "eosinophil: 1.3;memory B-cell: 3.7;naive B-cell: 3.9" "Group enriched" "Detected in many" 27 "B-cells: 3.9;granulocytes: 1.3" "Cancer enhanced" "Detected in many" "lymphoma: 9.1" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB025973 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Ciliated cells - Cilium assembly" 1 "CAB025973: " "unprognostic (9.38e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-3)" "unprognostic (2.54e-1)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.67e-2)" "unprognostic (1.10e-1)" "unprognostic (8.44e-3)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (7.24e-3)" "unprognostic (5.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.66e-1)" "unprognostic (9.42e-2)" HS6ST2 HS6ST-2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626015-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.4;kidney: 15.3;ovary: 15.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.8;Excitatory neurons: 36.3;Inhibitory neurons: 42.4;Leydig cells: 60.8;Oligodendrocyte precursor cells: 50.9;Peritubular cells: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Ascending Loop of Henle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "Plasma membrane" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 86.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 243.0;kidney: 326.2;salivary gland: 252.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 140.0;Distal enterocytes: 701.0;Enteroendocrine cells: 133.5;Intestinal goblet cells: 254.5;Paneth cells: 272.9;Proximal enterocytes: 247.9;Syncytiotrophoblasts: 165.6" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0;prostate cancer: 15.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032443, HPA042186, HPA056385" Enhanced Supported Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 5 "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 416.6;liver: 211.1;placenta: 368.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 148.8;Distal enterocytes: 179.9;Hepatocytes: 120.4;Paneth cells: 202.6;Proximal enterocytes: 399.3" "Group enriched" "Detected in many" 4 "liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 31.8;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 5: Enterocytes - Absorption" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: AB_2681059" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.83e-4)" HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.8;testis: 35.7" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 86.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Approved Vesicles NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" Vesicles "HPA056833: AB_2683252" "unprognostic (2.78e-1)" "unprognostic (6.61e-3)" "unprognostic (1.03e-1)" "unprognostic (5.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (3.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.13e-2)" "unprognostic (3.26e-4)" "unprognostic (3.45e-1)" "unprognostic (5.48e-8)" "unprognostic (8.47e-3)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (3.11e-2)" HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812823 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" "HPA047496: AB_2680068" "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 75.2" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 697.5" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 15.5;Gastric cancer: 12.8;testis cancer: 24.4" "Skin - Sebaceous gland cells" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 58: Placenta - Pregnancy" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 8 "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2106.0" "Cell type enriched" "Detected in some" 16 "Proximal enterocytes: 51.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "skin cancer: 9.2" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 2 "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 133.1" "Cell type enhanced" "Detected in many" "Ductal cells: 41.1;Hepatocytes: 57.6;Hofbauer cells: 48.1;Proximal enterocytes: 44.8;Proximal tubular cells: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.4;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 42 "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 3: Non-specific - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 66: Photoreceptor cells - Visual perception" Mitochondria "Vesicles, Intermediate filaments" "HPA045745: AB_2679440" "unprognostic (2.16e-1)" "unprognostic (4.32e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-3)" "unprognostic (3.66e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.25e-2)" "unprognostic (7.43e-2)" "unprognostic (3.39e-2)" "unprognostic (6.42e-2)" "unprognostic (3.66e-1)" "prognostic favorable (4.20e-7)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" HTR1A "5-HT1A, ADRB2RL1, ADRBRL1" ENSG00000178394 "5-hydroxytryptamine receptor 1A" P08908 5 63957874-63962507 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 2.0;ovary: 1.4" "Group enriched" "Detected in some" 6 "Leydig cells: 6.4;Ovarian stromal cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Rhabdoid: 8.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018073 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 6: Ovarian stromal cells - Transcription" 2 "HPA018073: AB_1856704" "unprognostic (1.81e-1)" HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9;placenta: 6.4;stomach 1: 4.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.9;Smooth muscle cells: 1.2" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 12.0" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" HTR1E 5-HT1E ENSG00000168830 "5-hydroxytryptamine receptor 1E" P28566 6 86937528-87016679 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.3;ovary: 4.1" "Group enriched" "Detected in some" 18 "Excitatory neurons: 121.1;Inhibitory neurons: 99.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 2.3" "Colon - Colon enteroendocrine cells, Stomach - Chief cells" "Low region specificity" "Detected in many" HPA004931 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "HPA004931: AB_1856706" "unprognostic (2.25e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.25e-1)" HTR1F "5-HT1F, HTR1EL" ENSG00000179097 "5-hydroxytryptamine receptor 1F" P30939 3 87792706-87993839 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.7;retina: 3.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 224.7;Inhibitory neurons: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Leukemia: 1.3;thyroid cancer: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005555 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA005555: AB_1856708" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.03e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (4.78e-1)" "unprognostic (1.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (2.67e-6)" "unprognostic (1.25e-4)" "unprognostic (1.55e-2)" "unprognostic (3.33e-2)" "unprognostic (3.31e-2)" HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 18.8" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 79.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.6" "Prostate - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.8;cervix: 20.7;endometrium 1: 18.2;smooth muscle: 16.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 16.5;Microglial cells: 4.5;Peritubular cells: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.9;T-cells: 1.0" "Group enriched" "Detected in some" 7 "Rhabdoid: 18.6;skin cancer: 13.6" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 2 Nucleoplasm "HPA012867: AB_1856710, HPA063658: AB_2685079" "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" HTR3A "5-HT3A, 5-HT3R, HTR3" ENSG00000166736 "5-hydroxytryptamine receptor 3A" P46098 11 113975075-113990313 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.5;intestine: 2.0;lymphoid tissue: 7.8;pancreas: 2.5;salivary gland: 4.8" "Group enriched" "Detected in some" 5 "Ductal cells: 25.0;Exocrine glandular cells: 71.5;Pancreatic endocrine cells: 23.8" "Cancer enriched" "Detected in many" 7 "ovarian cancer: 15.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 15 "memory B-cell: 3.9;naive B-cell: 13.9;plasmacytoid DC: 11.6" "Group enriched" "Detected in many" 128 "B-cells: 13.9;dendritic cells: 11.6" "Group enriched" "Detected in some" 9 "lymphoma: 15.4;Neuroblastoma: 12.9" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "amygdala: 2.7;cerebral cortex: 4.1;hippocampal formation: 3.9" HPA069442 Supported NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Non-specific - Mixed function" 3 "HPA069442: AB_2732132" "unprognostic (6.46e-3)" "prognostic favorable (6.26e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.36e-3)" "unprognostic (8.36e-3)" "unprognostic (1.65e-5)" "unprognostic (1.46e-2)" "unprognostic (8.87e-2)" "unprognostic (6.21e-2)" "unprognostic (6.80e-3)" "unprognostic (3.00e-2)" "unprognostic (1.65e-2)" "unprognostic (8.72e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.40e-2)" HTR3B 5-HT3B ENSG00000149305 "5-hydroxytryptamine receptor 3B" O95264 11 113904796-113949079 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.3;Melanocytes: 1.7;Rod photoreceptor cells: 1.6;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 2.9" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039559 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA039559: AB_10672779" "unprognostic (1.60e-2)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "unprognostic (3.28e-1)" "unprognostic (1.71e-1)" "unprognostic (2.46e-1)" HTR3E ENSG00000186038 "5-hydroxytryptamine receptor 3E" A5X5Y0 3 184097064-184106995 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 1.0;Oligodendrocyte precursor cells: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049764 Enhanced NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA049764: AB_2680869" "unprognostic (4.12e-2)" "unprognostic (5.86e-2)" "unprognostic (2.15e-1)" "unprognostic (4.57e-4)" "unprognostic (3.61e-3)" "unprognostic (1.15e-1)" "unprognostic (3.16e-1)" "unprognostic (4.47e-1)" "unprognostic (3.32e-1)" "unprognostic (2.67e-1)" "unprognostic (4.16e-2)" HTR4 5-HT4 ENSG00000164270 "5-hydroxytryptamine receptor 4" Q13639 5 148446042-148677235 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.9;heart muscle: 4.4;intestine: 8.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 40.6;Inhibitory neurons: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040591 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA040591: AB_2677028" "unprognostic (1.12e-1)" "unprognostic (4.60e-2)" "unprognostic (7.74e-2)" "unprognostic (2.37e-1)" "unprognostic (5.02e-2)" "unprognostic (3.77e-2)" "unprognostic (4.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (3.40e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-2)" "unprognostic (8.83e-5)" HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155087392 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "brain: 15.2" "Cell type enhanced" "Detected in some" "Early spermatids: 10.8;Excitatory neurons: 7.3;Inhibitory neurons: 9.6;Late spermatids: 12.2;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" CAB017467 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "CAB017467: AB_2122566" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" HTR6 "5-HT6, 5-HT6R" ENSG00000158748 "5-hydroxytryptamine receptor 6" P50406 1 19664875-19680966 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.6;Spermatogonia: 1.1" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Region enhanced" "Detected in many" "basal ganglia: 22.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;Rhabdoid: 3.2" "Low region specificity" "Detected in many" HPA068165 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 3 "HPA068165: " "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (7.19e-3)" "unprognostic (3.84e-5)" "unprognostic (1.38e-4)" "unprognostic (2.69e-2)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (5.33e-3)" "unprognostic (8.63e-2)" "unprognostic (5.47e-4)" "unprognostic (1.28e-1)" "unprognostic (2.49e-1)" "unprognostic (6.13e-3)" "unprognostic (2.02e-1)" HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "parathyroid gland: 12.7;testis: 8.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Excitatory neurons: 5.7;Inhibitory neurons: 23.4;Macrophages: 3.6;Spermatocytes: 10.9" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529596-74533350 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 260000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 1: Erythroid cells - Oxygen transport" 55 Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" HTT "HD, IT15" ENSG00000197386 Huntingtin P42858 4 3041363-3243957 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002756, HPA026114, HPA051524" Approved Supported Nucleoplasm,Cytosol NA NA 36000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Photoreceptor cells - Visual perception" 665 Nucleoplasm Cytosol "CAB002756: , HPA026114: AB_1851330, HPA051524: " "unprognostic (2.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.52e-2)" "unprognostic (8.33e-2)" "unprognostic (8.06e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-2)" "unprognostic (6.04e-2)" "prognostic favorable (2.41e-12)" "unprognostic (9.46e-3)" "unprognostic (1.99e-1)" "unprognostic (6.53e-2)" "unprognostic (3.84e-2)" HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1" Q7Z6Z7 X 53532096-53686752 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol NA NA 73000 "Cluster 29: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 6 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "choroid plexus: 520.1" "Cell type enhanced" "Detected in many" "B-cells: 179.8;dendritic cells: 69.3;Early spermatids: 87.2;Late spermatids: 71.4;Oocytes: 310.3;Spermatocytes: 95.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 319.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Leukemia: 33.4;lymphoma: 48.2;Myeloma: 30.4" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 276.0" "Group enriched" "Detected in all" 6 "Adipocytes: 483.6;Endothelial cells: 274.3;Lymphatic endothelial cells: 409.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 12 "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.8;skeletal muscle: 3.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.3;Cytotrophoblasts: 4.1;Extravillous trophoblasts: 8.5;Ionocytes: 1.5;Spermatocytes: 1.4;Spermatogonia: 3.8;Syncytiotrophoblasts: 2.3" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA029453 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 66: Non-specific - Mitochondria" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 474.8;Late spermatids: 941.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 30.0" "Lineage enriched" "Detected in many" 9 "T-cells: 30.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.4" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" 4 "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: AB_2684525" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 212.5;urinary bladder: 207.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 518.0;Alveolar cells type 2: 276.8;Endothelial cells: 318.0;Langerhans cells: 216.7;Macrophages: 230.4;monocytes: 345.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 164.0" "Cell type enhanced" "Detected in many" "Adipocytes: 346.2;Endothelial cells: 215.8;Lymphatic endothelial cells: 85.3;monocytes: 149.0;NK-cells: 86.1;Plasma cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 72.4;lymphoma: 56.2;Myeloma: 73.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 175.2;lymphoid tissue: 76.1" "Cell type enhanced" "Detected in many" "B-cells: 144.5;Hepatocytes: 174.9;monocytes: 235.7;NK-cells: 242.4;Plasma cells: 174.7;T-cells: 176.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1772.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 1772.8" "Cancer enhanced" "Detected in all" "Leukemia: 103.0;Myeloma: 120.8" "Adipose subcutaneous - T-cells, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Lung - Neutrophil_2, Prostate - T-cells" "Low region specificity" "Detected in many" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 8 Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" ICAM5 "TLCN, TLN" ENSG00000105376 "Intercellular adhesion molecule 5" Q9UMF0 19 10289952-10296778 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 25.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 14.2;Alveolar cells type 2: 15.0;Breast myoepithelial cells: 5.8;Excitatory neurons: 17.1;Mesothelial cells: 7.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.8" "Group enriched" "Detected in many" 5 "amygdala: 74.9;basal ganglia: 78.1;cerebral cortex: 97.2;hippocampal formation: 142.6;white matter: 37.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 24.0" "Colon - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 15 "amygdala: 54.3;basal ganglia: 59.8;cerebral cortex: 67.0;hippocampal formation: 100.2;olfactory bulb: 36.8" "HPA008943, HPA009083, CAB025178" Enhanced NA NA 3300000 "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 22 "CAB025178: , HPA008943: AB_1079095, HPA009083: AB_1079094" "unprognostic (7.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.66e-2)" "unprognostic (4.24e-2)" "unprognostic (8.23e-3)" "unprognostic (2.58e-1)" "unprognostic (8.12e-2)" "unprognostic (9.99e-3)" "unprognostic (2.58e-1)" "unprognostic (2.44e-2)" "unprognostic (3.90e-3)" "unprognostic (9.89e-3)" "unprognostic (5.29e-5)" "unprognostic (6.47e-2)" "unprognostic (4.86e-2)" "unprognostic (5.44e-3)" "unprognostic (6.28e-3)" ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 54: Immune cells - T cell receptor" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.3;lymphoid tissue: 19.6" "Cell type enriched" "Detected in some" 16 "T-cells: 96.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.2" "Lineage enriched" "Detected in single" 54 "T-cells: 29.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.4;lymphoma: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" "No annotated function" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" ICOSLG "B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653" ENSG00000160223 "Inducible T cell costimulator ligand" O75144 21 44215382-44241446 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, B-cell activation, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 69.4;Langerhans cells: 34.3;Schwann cells: 48.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026037, HPA029179, CAB079997" Approved Approved "Vesicles,Plasma membrane" NA NA 130000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Vesicles, Plasma membrane" "CAB026037: , CAB079997: , HPA029179: AB_2732445" "unprognostic (3.03e-2)" "unprognostic (1.40e-4)" "unprognostic (3.52e-2)" "unprognostic (1.94e-2)" "unprognostic (6.74e-2)" "unprognostic (9.40e-2)" "unprognostic (6.94e-2)" "unprognostic (3.71e-1)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-1)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.84e-1)" IER3 "DIF-2, IEX-1, IEX-1L, PRG1" ENSG00000137331 "Immediate early response 3" P46695 6 30743199-30744548 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 2947.6;Suprabasal keratinocytes: 2113.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 30.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043847 Approved NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 11 "HPA043847: AB_2678699" "unprognostic (2.83e-3)" "unprognostic (9.04e-3)" "unprognostic (1.22e-1)" "unprognostic (2.78e-2)" "unprognostic (9.63e-3)" "prognostic unfavorable (5.57e-4)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.38e-3)" "unprognostic (1.69e-1)" "unprognostic (9.28e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.10e-7)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.71e-2)" "unprognostic (8.77e-2)" IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 34 "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116695 "Plasma proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3514.8;Distal enterocytes: 4034.6;Endothelial cells: 1661.3;Intestinal goblet cells: 2206.2;Paneth cells: 1871.2;Proximal enterocytes: 3099.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 8.2" "Group enriched" "Detected in many" 5 "monocytes: 8.2;T-cells: 3.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 766.6" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" HPA028875 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 554.6;lymphoid tissue: 688.9" "Group enriched" "Detected in many" 4 "Hofbauer cells: 205.3;Kupffer cells: 132.8;Langerhans cells: 136.5;Macrophages: 255.7;monocytes: 168.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9529.3;eosinophil: 3901.6;intermediate monocyte: 14264.3;myeloid DC: 5706.8;non-classical monocyte: 9916.5" "Group enriched" "Detected in all" 8 "dendritic cells: 5706.8;granulocytes: 3901.6;monocytes: 14264.3" "Cancer enhanced" "Detected in all" "lymphoma: 572.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" Immunity NA NA 110000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 3 "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" IFI6 "6-16, FAM14C, G1P3, IFI-6-16, IFI616" ENSG00000126709 "Interferon alpha inducible protein 6" P09912 1 27666064-27672212 "Predicted membrane proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "choroid plexus: 3448.1" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 2219.0;Extravillous trophoblasts: 634.8;Syncytiotrophoblasts: 2232.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA005543 Approved Supported Mitochondria NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" Mitochondria "HPA005543: AB_1849342" "unprognostic (4.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (6.96e-2)" "unprognostic (9.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (6.77e-3)" "unprognostic (5.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.92e-3)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 347.5;Endothelial cells: 319.6;Leydig cells: 223.1;Mesothelial cells: 297.5;NK-cells: 253.8;T-cells: 487.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1500.1;gdT-cell: 2915.2;MAIT T-cell: 2008.6;memory CD4 T-cell: 3131.5;memory CD8 T-cell: 3002.0;naive CD4 T-cell: 2949.8;naive CD8 T-cell: 3007.1;neutrophil: 2758.0;NK-cell: 4694.8;T-reg: 1950.8" "Group enriched" "Detected in all" 7 "granulocytes: 2758.0;NK-cells: 4694.8;T-cells: 3131.5" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 7: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 2696.9;NK-cells: 1421.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23257.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23257.9" "Low cancer specificity" "Detected in all" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 450000 "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 74: Neutrophils - Degranulation" "Cell Junctions" Nucleoplasm "HPA004337: AB_1851427, HPA044731: " "unprognostic (2.39e-2)" "unprognostic (2.69e-2)" "unprognostic (4.54e-1)" "unprognostic (1.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.87e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.37e-9)" "unprognostic (2.79e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" IFITM3 "1-8U, DSPA2b" ENSG00000142089 "Interferon induced transmembrane protein 3" Q01628 11 319676-329475 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 2343.9;Mesothelial cells: 3574.1;Secretory cells: 2687.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2953.0;non-classical monocyte: 3364.2" "Group enriched" "Detected in all" 6 "granulocytes: 2953.0;monocytes: 3364.2;NK-cells: 928.9" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" HPA004337 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 49: Non-specific - Transcription" 22 "HPA004337: AB_1851427" "unprognostic (4.17e-2)" "unprognostic (4.19e-1)" "unprognostic (1.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.55e-3)" "unprognostic (6.00e-2)" "unprognostic (3.36e-2)" "unprognostic (6.44e-2)" "unprognostic (8.90e-2)" "unprognostic (9.42e-2)" "unprognostic (7.45e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (5.78e-7)" "unprognostic (7.81e-2)" "unprognostic (3.34e-2)" "unprognostic (8.28e-2)" "unprognostic (1.19e-1)" IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "pancreas: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 7 "cerebral cortex: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" IFNAR1 "IFNAR, IFRC" ENSG00000142166 "Interferon alpha and beta receptor subunit 1" P17181 21 33324387-33359864 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029226 Approved NA NA 170000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 3 "HPA029226: AB_2672954" "unprognostic (2.42e-3)" "unprognostic (2.95e-1)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (3.02e-1)" "unprognostic (4.69e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.38e-1)" "unprognostic (9.38e-3)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (8.45e-2)" "unprognostic (3.06e-2)" IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197483-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 840.3;Ionocytes: 628.8;monocytes: 682.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" IFNGR2 "AF-1, IFNGT1" ENSG00000159128 "Interferon gamma receptor 2" P38484 21 33403413-33479348 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 267.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 671.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001535 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Monocytes - Innate immune response" 28 "Nucleoplasm, Golgi apparatus" "HPA001535: AB_1078432" "unprognostic (9.58e-2)" "unprognostic (5.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (3.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.53e-2)" "unprognostic (3.25e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (1.13e-10)" "unprognostic (6.74e-3)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (2.15e-3)" IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.3;dendritic cells: 14.7;Proximal enterocytes: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.4" "Cancer enhanced" "Detected in many" "lymphoma: 20.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.3;neutrophil: 112.7" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024122, HPA072413" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA024122: AB_1851452, HPA072413: " "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.10e-1)" "unprognostic (9.82e-3)" "unprognostic (1.36e-2)" "unprognostic (2.39e-1)" "unprognostic (5.73e-3)" "unprognostic (1.37e-1)" "unprognostic (2.48e-2)" "prognostic favorable (5.45e-4)" "unprognostic (6.41e-2)" "unprognostic (2.93e-3)" "unprognostic (1.50e-3)" "unprognostic (4.81e-2)" "unprognostic (1.98e-1)" "unprognostic (2.89e-1)" "unprognostic (4.70e-2)" IFRD2 "IFNRP, SKMc15, SM15" ENSG00000214706 "Interferon related developmental regulator 2" Q12894 3 50287732-50292918 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 153.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068560 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm "HPA068560: AB_2686005" "prognostic favorable (7.22e-4)" "unprognostic (5.19e-2)" "unprognostic (2.08e-2)" "unprognostic (8.61e-3)" "unprognostic (3.88e-1)" "unprognostic (2.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.01e-1)" "unprognostic (1.91e-2)" "unprognostic (7.78e-3)" "prognostic favorable (2.50e-4)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" IGDCC3 "HsT18880, PUNC" ENSG00000174498 "Immunoglobulin superfamily DCC subclass member 3" Q8IVU1 15 65327127-65378002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;parathyroid gland: 5.0;placenta: 5.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 102.5;Early spermatids: 23.3;Late spermatids: 99.6;Oocytes: 30.9;Syncytiotrophoblasts: 35.4" "Group enriched" "Detected in many" 5 "glioma: 2.2;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.6;testis cancer: 38.6" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015713 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Cytotrophoblasts - Mitochondria" "Nucleoplasm, Vesicles" "HPA015713: " "unprognostic (7.11e-2)" "unprognostic (1.99e-1)" "unprognostic (4.24e-2)" "unprognostic (7.25e-3)" "unprognostic (6.67e-2)" "unprognostic (7.35e-3)" "unprognostic (3.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-2)" "unprognostic (4.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.77e-5)" "unprognostic (4.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-2)" IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 10.2;tongue: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 17.6;Cone photoreceptor cells: 11.9;Fibroblasts: 10.7;Leydig cells: 33.4;Melanocytes: 17.2;Microglial cells: 13.4;Oligodendrocyte precursor cells: 16.5;Rod photoreceptor cells: 13.2;Skeletal myocytes: 21.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.0" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648539-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 231.4;Inhibitory neurons: 186.7;Microglial cells: 234.4;Oligodendrocyte precursor cells: 223.1;Oligodendrocytes: 242.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 4.3;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved NA NA 46000 "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Neuronal - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Glandular & Luminal cells - Unknown function" 21 "CAB010268: AB_671792, HPA045563: AB_2679368" "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2158391 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "placenta: 2670.3" "Cell type enhanced" "Detected in some" "Adipocytes: 75.8;Cytotrophoblasts: 117.3;Extravillous trophoblasts: 251.5;Leydig cells: 162.0;Syncytiotrophoblasts: 175.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 618.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 597.2;Sarcoma: 625.3" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007556 Enhanced Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 609000000 1200000000 "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 "Golgi apparatus" "HPA007556: AB_2667860" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 67.0" "Cell type enhanced" "Detected in many" "dendritic cells: 200.3;NK-cells: 202.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Supported "Golgi apparatus,Vesicles" NA NA 190000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 74: Neutrophils - Degranulation" 4 "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.08e-4)" IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 113.8" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 65.5" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040692, HPA040948" Supported "Secreted to blood" "Cell adhesion" NA NA 14700000000 26000000000 "Cluster 83: Liver - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.7" "Cell type enhanced" "Detected in many" "B-cells: 20.3;dendritic cells: 42.6;Hepatocytes: 21.0;Langerhans cells: 44.5;Macrophages: 21.5;Plasma cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 901.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 901.7" "Cancer enhanced" "Detected in all" "Myeloma: 17.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Spleen - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" IGHA1 AL928768.3 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7198.9;salivary gland: 4545.3;stomach 1: 6480.0" "Cell type enriched" "Detected in many" 16 "Plasma cells: 107776.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2579.2;naive B-cell: 1123.4" "Lineage enriched" "Detected in many" 282 "B-cells: 2579.2" "Cancer enriched" "Detected in some" 20 "Myeloma: 1517.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA 130000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 562.7" "Cell type enriched" "Detected in many" 30 "Plasma cells: 9424.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 878 "memory B-cell: 280.4;naive B-cell: 124.8" "Lineage enriched" "Detected in single" 1215 "B-cells: 280.4" "Cancer enriched" "Detected in some" 5 "Myeloma: 47.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA 67000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" 14 105836765-105845677 "Immunoglobulin genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 113.8" "Group enriched" "Detected in some" 28 "B-cells: 449.9;Plasma cells: 1002.6" "Cancer enhanced" "Detected in many" "lung cancer: 58.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 147.4;naive B-cell: 464.1" "Lineage enriched" "Detected in many" 95 "B-cells: 464.1" "Cancer enriched" "Detected in some" 38 "Myeloma: 1117.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" CAB012703 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "CAB012703: AB_10554307" "prognostic favorable (1.49e-6)" "unprognostic (1.84e-2)" "unprognostic (3.99e-2)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-3)" "unprognostic (4.63e-2)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.30e-2)" IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 5665.1;urinary bladder: 3867.4" "Cell type enriched" "Detected in many" 5 "Plasma cells: 12047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 768.6" "Lineage enriched" "Detected in many" 122 "B-cells: 768.6" "Cancer enriched" "Detected in some" 8 "Myeloma: 1184.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001245, CAB008642" Supported "Immunoglobulin genes" Immunity NA NA 230000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 1 "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 189.5;urinary bladder: 108.3" "Cell type enriched" "Detected in some" 11 "Plasma cells: 4935.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 460 "memory B-cell: 344.6;naive B-cell: 128.5" "Lineage enriched" "Detected in single" 670 "B-cells: 344.6" "Group enriched" "Detected in some" 9 "lymphoma: 19.2;Myeloma: 54.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA 250000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2402.4" "Group enriched" "Detected in some" 4 "B-cells: 423.0;Plasma cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 123.0;naive B-cell: 74.3" "Lineage enriched" "Detected in single" 569 "B-cells: 123.0" "Group enriched" "Detected in some" 43 "lymphoma: 133.6;Myeloma: 34.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA 170000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 1279.4;lymphoid tissue: 3116.6" "Group enriched" "Detected in some" 8 "B-cells: 2732.6;Plasma cells: 9466.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 16 "memory B-cell: 4293.6;naive B-cell: 6750.1" "Lineage enriched" "Detected in all" 19 "B-cells: 6750.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 1665.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008643 Uncertain "Immunoglobulin genes" Immunity NA NA 110000000000 "Cluster 18: Non-specific - Translation" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 163.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.7;Bipolar cells: 10.7;Breast glandular cells: 3.7;Granulosa cells: 3.2;Pancreatic endocrine cells: 5.1;Schwann cells: 9.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Region enhanced" "Detected in all" "hypothalamus: 153.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Breast - Breast glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "hypothalamus: 144.1" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" Receptor NA NA 100000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0;retina: 49.1;testis: 34.7" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Early spermatids: 233.3;Excitatory neurons: 75.2;Inhibitory neurons: 133.1;Late spermatids: 345.5;Oligodendrocytes: 263.5" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Myeloma: 4.9;skin cancer: 17.6" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 65: Neurons - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 15.4;liver: 23.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.6;Enteroendocrine cells: 5.7;Hepatocytes: 14.6;Late spermatids: 11.7;Proximal enterocytes: 40.7" "Cancer enriched" "Detected in some" 10 "liver cancer: 12.4" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.4" "Pancreas - Ductal cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA051811: AB_2681621" "unprognostic (1.54e-1)" "unprognostic (1.84e-3)" "unprognostic (5.74e-2)" "unprognostic (1.53e-3)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.20e-6)" "unprognostic (7.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-3)" "unprognostic (1.52e-1)" "unprognostic (1.19e-8)" "unprognostic (1.26e-1)" "unprognostic (6.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.85e-1)" IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 12: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA036305: AB_2675050, HPA036306: AB_10671245" "unprognostic (9.87e-2)" "unprognostic (3.64e-1)" "unprognostic (9.51e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (4.03e-6)" "unprognostic (9.40e-2)" "unprognostic (4.41e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.87e-6)" "unprognostic (5.29e-2)" "unprognostic (4.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745183-39802081 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 9 "Syncytiotrophoblasts: 138.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 29.1" "Group enriched" "Detected in many" 9 "Hofbauer cells: 261.2;Kupffer cells: 227.4;Langerhans cells: 197.5;Macrophages: 307.4;monocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1230.0" "Lineage enhanced" "Detected in all" "granulocytes: 1230.0" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 153.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 247.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 4: Extravillous trophoblasts - Unknown function" 9 Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" IGSF9 "IGSF9A, KIAA1355, Nrt1" ENSG00000085552 "Immunoglobulin superfamily member 9" Q9P2J2 1 159927039-159945613 "Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.2;retina: 27.3;skin 1: 22.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.3;Distal enterocytes: 66.5;Gastric mucus-secreting cells: 31.8;Rod photoreceptor cells: 171.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebellum: 7.5" HPA037753 Uncertain NA NA 140000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" "HPA037753: AB_10672915" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (3.30e-2)" "unprognostic (6.06e-3)" "unprognostic (8.93e-3)" "unprognostic (1.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (2.87e-1)" "unprognostic (8.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" IGSF9B "KIAA1030, LINC00947, LOC283174, MIR4697HG" ENSG00000080854 "Immunoglobulin superfamily member 9B" Q9UPX0 11 133896438-133956968 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.7;Excitatory neurons: 24.4;Horizontal cells: 79.3;Muller glia cells: 15.2;Oligodendrocyte precursor cells: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010802 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Golgi apparatus, Cell Junctions" "HPA010802: AB_1079194" "unprognostic (9.04e-4)" "unprognostic (1.74e-2)" "unprognostic (7.52e-3)" "unprognostic (4.38e-4)" "unprognostic (8.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.17e-2)" "unprognostic (1.38e-1)" "unprognostic (8.10e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-4)" "unprognostic (3.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (9.14e-4)" "unprognostic (3.12e-3)" IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 5 "Endoplasmic reticulum" "Nucleoli rim" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 168.0;lymphoid tissue: 103.5" "Cell type enhanced" "Detected in many" "B-cells: 159.5;dendritic cells: 372.8;Erythroid cells: 103.4;granulocytes: 113.9;Langerhans cells: 114.1;monocytes: 112.1;NK-cells: 318.0;T-cells: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 104 "Leukemia: 88.6;lymphoma: 129.9;Myeloma: 44.5" "Adipose visceral - T-cells, Colon - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 50 Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.1;lymphoid tissue: 71.9" "Cell type enhanced" "Detected in many" "dendritic cells: 86.1;Extravillous trophoblasts: 105.7;Hofbauer cells: 91.4;Kupffer cells: 163.9;Langerhans cells: 181.9;Macrophages: 131.9;monocytes: 262.6;NK-cells: 104.4;Plasma cells: 93.4;T-cells: 111.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 28.7;Myeloma: 13.1" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 25 "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33311420 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.6;Paneth cells: 43.6;Proximal enterocytes: 54.4;Syncytiotrophoblasts: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 1600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 49: Non-specific - Transcription" 2 Cytosol "CAB020670: , HPA047550: AB_2680086" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-2)" "unprognostic (7.78e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-1)" "unprognostic (5.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.62e-9)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34652162-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 49.2;Late spermatids: 98.4;Sertoli cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.6" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652, HPA036653" Supported Approved "Vesicles,Plasma membrane" "Secreted to blood" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 53: Fibroblasts - ECM organization" 1 "Vesicles, Plasma membrane" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229, HPA036653: " "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" IL12A "CLMF, IL-12A, NFSK, NKSF1, p35" ENSG00000168811 "Interleukin 12A" P29459 3 159988835-159996019 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.2;Oligodendrocyte precursor cells: 3.8;Plasma cells: 2.9;Schwann cells: 4.0;Spermatogonia: 2.7;Squamous epithelial cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Not detected" "Not detected" HPA001886 Uncertain "Secreted to blood" Interleukin NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" 1 "HPA001886: AB_1079132" "unprognostic (6.23e-2)" "unprognostic (7.82e-5)" "unprognostic (1.25e-1)" "unprognostic (3.10e-2)" "unprognostic (4.22e-1)" "unprognostic (7.18e-2)" "unprognostic (4.18e-5)" "unprognostic (2.22e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (9.57e-10)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (9.61e-2)" IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.7" "Cell type enhanced" "Detected in some" "Kupffer cells: 12.2;monocytes: 36.4;NK-cells: 54.6;Plasma cells: 11.0;T-cells: 26.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 9.4;lymphoma: 19.8;Myeloma: 26.5" "Breast - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.4;skeletal muscle: 3.4" "Group enriched" "Detected in some" 4 "Erythroid cells: 5.7;Excitatory neurons: 21.7;Hofbauer cells: 8.9;Inhibitory neurons: 15.8;Melanocytes: 8.6;NK-cells: 18.0;T-cells: 14.9" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 4.8;NK-cell: 15.9" "Group enriched" "Detected in many" 41 "NK-cells: 15.9;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;skin cancer: 5.2" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.1" "Cell type enhanced" "Detected in some" "Early spermatids: 345.4;Late spermatids: 109.8;Spermatocytes: 65.6" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Region enhanced" "Detected in many" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 77.2;Sarcoma: 84.5;skin cancer: 80.6" "Liver - Sinusoid Endothelial cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in many" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Early spermatids - Spermatogenesis" 5 "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 35.8;Exocrine glandular cells: 36.4;Fibroblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" CAB026215 Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Lung - Lung function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 53: Fibroblasts - ECM organization" 3 "Plasma membrane, Cytosol" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115693 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.7" "Cell type enhanced" "Detected in all" "dendritic cells: 77.9;Kupffer cells: 83.4;Macrophages: 65.6;monocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophil_2, Skin - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" Receptor NA NA 62000 "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 17.6;cervix: 17.4;kidney: 57.7;liver: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 45.8;Oligodendrocyte precursor cells: 35.4;Proximal tubular cells: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 15.5;Early spermatids: 14.5;Late spermatids: 22.4;Microglial cells: 14.3;Peritubular cells: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 8: Immune cells - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.2;skin 1: 30.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.7;Enteroendocrine cells: 36.9;Gastric mucus-secreting cells: 49.5;Intestinal goblet cells: 63.4;Paneth cells: 41.7;Proximal enterocytes: 67.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 2.9;cerebellum: 4.0;hypothalamus: 1.3;medulla oblongata: 1.4;pons: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 45: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 23.5;lymphoid tissue: 18.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 37.8;dendritic cells: 55.4;granulocytes: 126.7;Langerhans cells: 32.8;NK-cells: 47.0;Schwann cells: 26.2;T-cells: 36.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007615 Approved Approved Mitochondria Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 1 Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" IL18RAP "AcPL, CD218b" ENSG00000115607 "Interleukin 18 receptor accessory protein" O95256 2 102418689-102452565 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 106.6;lymphoid tissue: 45.6" "Group enriched" "Detected in some" 7 "NK-cells: 75.1;T-cells: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 120.7" "Group enriched" "Detected in many" 104 "granulocytes: 69.6;NK-cells: 120.7;T-cells: 67.5" "Group enriched" "Detected in some" 20 "Leukemia: 2.6;lymphoma: 1.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" CAB025270 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB025270: " "unprognostic (1.73e-3)" "unprognostic (6.27e-3)" "unprognostic (5.07e-3)" "unprognostic (4.64e-6)" "unprognostic (2.90e-1)" "unprognostic (1.18e-2)" "unprognostic (5.86e-5)" "unprognostic (5.09e-3)" "unprognostic (4.02e-2)" "unprognostic (1.57e-3)" "unprognostic (4.78e-2)" "unprognostic (5.31e-2)" "unprognostic (1.51e-2)" "unprognostic (2.71e-1)" "unprognostic (6.35e-2)" "unprognostic (8.56e-2)" "unprognostic (2.73e-2)" IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 303.4;Glandular and luminal cells: 312.5;Langerhans cells: 221.8;Mesothelial cells: 245.0;Prostatic glandular cells: 291.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 1400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 5 "Langerhans cells: 1470.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Region enhanced" "Detected in many" "cerebral cortex: 14.5" "Immune cell enriched" "Detected in some" 26 "neutrophil: 378.7" "Lineage enriched" "Detected in many" 26 "granulocytes: 378.7" "Cancer enhanced" "Detected in many" "lymphoma: 66.7" "Adipose visceral - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" Receptor NA NA 7130000 27000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 218.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 125.7;Hepatocytes: 315.4;Oligodendrocyte precursor cells: 280.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 23.9;neutrophil: 95.8" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.8" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" Receptor NA NA 350000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 43: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 59.9;kidney: 122.8;lung: 157.1;placenta: 193.2" "Cell type enriched" "Detected in many" 6 "granulocytes: 1024.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.4;eosinophil: 29.4" "Lineage enriched" "Detected in single" 73 "granulocytes: 38.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 24.0;pancreatic cancer: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" Receptor NA NA 19100000 3100000 "Cluster 41: Basophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 1 "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 36.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.7;Ciliated cells: 62.0;Glandular and luminal cells: 71.8;Muller glia cells: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.8" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 Cytosol "CAB024990: , HPA042281: AB_10806235" "unprognostic (3.75e-2)" "unprognostic (8.23e-2)" "unprognostic (1.96e-2)" "prognostic favorable (1.43e-6)" "unprognostic (1.57e-2)" "prognostic favorable (2.29e-5)" "unprognostic (9.87e-3)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (8.03e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-6)" "unprognostic (9.38e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-3)" "unprognostic (1.64e-3)" IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 107.6;skin 1: 159.0;vagina: 64.1" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 58.0;Basal respiratory cells: 112.2;Basal squamous epithelial cells: 53.0;Club cells: 29.7;Early spermatids: 71.4;Ionocytes: 46.0;Late spermatids: 32.1;Squamous epithelial cells: 58.3;Suprabasal keratinocytes: 102.6" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 56.6;head and neck cancer: 79.1" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 7.4;lymphoid tissue: 23.9" "Cell type enhanced" "Detected in some" "B-cells: 12.1;Langerhans cells: 19.3;monocytes: 14.7;NK-cells: 29.2;T-cells: 24.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 53.9;Myeloma: 24.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042296 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" IL23R IL-23R ENSG00000162594 "Interleukin 23 receptor" Q5VWK5 1 67138907-67259979 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.3;intestine: 1.1;testis: 1.1" "Group enriched" "Detected in some" 4 "Early spermatids: 12.5;Late spermatids: 7.4;Oocytes: 5.1;T-cells: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 24.1" "Lineage enriched" "Detected in single" 27 "T-cells: 24.1" "Cancer enhanced" "Detected in some" "Leukemia: 2.9;lymphoma: 3.3" "Adipose visceral - T-cells, Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056427 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA056427: AB_2683129" "unprognostic (4.01e-3)" "unprognostic (8.04e-2)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.16e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (8.64e-5)" "unprognostic (1.43e-1)" "unprognostic (3.02e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.1" "Cell type enhanced" "Detected in many" "B-cells: 43.2;Kupffer cells: 37.8;Langerhans cells: 63.6;NK-cells: 55.9;T-cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073441 Approved Vesicles NA NA 4900000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 7 Vesicles "HPA073441: " "prognostic favorable (1.74e-6)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (6.09e-2)" "unprognostic (2.03e-3)" "unprognostic (2.28e-1)" "unprognostic (2.05e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-3)" "unprognostic (9.92e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (2.58e-10)" "unprognostic (5.45e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.87e-3)" IL2RA "CD25, IDDM10, IL2R" ENSG00000134460 "Interleukin 2 receptor subunit alpha" P01589 10 6010689-6062370 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Immunity Receptor "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.1;lymphoid tissue: 17.5;urinary bladder: 10.5" "Cell type enhanced" "Detected in some" "B-cells: 12.1;granulocytes: 21.6;Kupffer cells: 7.5;Macrophages: 11.7;NK-cells: 12.2;T-cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 8 "basophil: 192.6;T-reg: 271.0" "Group enriched" "Detected in many" 15 "granulocytes: 192.6;T-cells: 271.0" "Cancer enriched" "Detected in some" 31 "lymphoma: 158.1" "Heart muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002419, HPA054622" Enhanced NA NA 410000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 14: Langerhans cells - Innate immune response" 1 "CAB002419: AB_563538, HPA054622: AB_2682546" "unprognostic (2.82e-1)" "unprognostic (8.10e-3)" "unprognostic (1.75e-2)" "unprognostic (5.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-3)" "unprognostic (2.78e-2)" "unprognostic (2.73e-1)" "unprognostic (5.03e-2)" "unprognostic (6.32e-2)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.08e-9)" "unprognostic (2.10e-2)" "unprognostic (4.66e-2)" "unprognostic (2.22e-1)" "unprognostic (5.10e-2)" IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37118666-37175118 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.4;lymphoid tissue: 48.0" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 97.1;NK-cells: 299.6;T-cells: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "gdT-cell: 49.8;NK-cell: 184.0" "Group enriched" "Detected in many" 30 "NK-cells: 184.0;T-cells: 49.8" "Cancer enriched" "Detected in some" 8 "lymphoma: 69.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in many" HPA062657 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 4 "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 112.7;lymphoid tissue: 332.3" "Cell type enhanced" "Detected in many" "B-cells: 111.4;dendritic cells: 92.3;Distal enterocytes: 97.2;Langerhans cells: 150.0;NK-cells: 280.1;Plasma cells: 127.0;Proximal enterocytes: 79.5;T-cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 207.1;lymphoma: 145.1;Myeloma: 354.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046641, CAB080341" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA 13000 "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 6 "Nucleoplasm, Plasma membrane" "Endoplasmic reticulum" "CAB080341: , HPA046641: AB_2679733" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.0;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.5;granulocytes: 1.6;Late spermatids: 1.6;Prostatic glandular cells: 2.1;Spermatocytes: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.6" HPA068114 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 4: Testis - Basic cellular processes" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 79.5;dendritic cells: 466.3;Endothelial cells: 81.2;Langerhans cells: 57.8;Oocytes: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2669.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2669.0" "Cancer enhanced" "Detected in many" "Leukemia: 20.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "HPA003539, CAB018374" Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 17 "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 71.7;granulocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 77.1" "Group enriched" "Detected in all" 5 "B-cells: 77.1;granulocytes: 31.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 139.2" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 38500 110000 "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 3 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.6;urinary bladder: 265.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 239.2;Fibroblasts: 109.1;Glandular and luminal cells: 328.1;monocytes: 160.7;Smooth muscle cells: 310.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 15.1" "Group enriched" "Detected in some" 47 "memory B-cell: 4.1;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 52 "B-cells: 5.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 219.1" "Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" "Acute phase" NA NA 5700 "Cluster 14: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" 5 Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" IL6ST "CD130, GP130, IL-6RB, sGP130" ENSG00000134352 "Interleukin 6 cytokine family signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 689.8;Mesothelial cells: 413.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 22.8" "Lineage enriched" "Detected in many" 5 "T-cells: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" IL7R "CD127, IL7RA, lnc-IL7R" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 178.8" "Cell type enriched" "Detected in many" 6 "T-cells: 1368.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 102.3;MAIT T-cell: 370.2;memory CD4 T-cell: 214.4;memory CD8 T-cell: 151.1;naive CD4 T-cell: 180.0;naive CD8 T-cell: 125.1;NK-cell: 113.4" "Group enriched" "Detected in all" 34 "NK-cells: 113.4;T-cells: 370.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 610000 "Cluster 27: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 10 "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" IL9R CD129 ENSG00000124334 "Interleukin 9 receptor" Q01113 X 155997696-156010817 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.3;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "granulocytes: 1.7;T-cells: 2.3" "Group enriched" "Detected in some" 4 "cervical cancer: 0.7;urothelial cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.5" "Group enriched" "Detected in many" 23 "B-cells: 1.9;granulocytes: 3.5;T-cells: 1.4" "Group enriched" "Detected in some" 7 "Leukemia: 18.3;lymphoma: 14.4" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063240, HPA064557" Approved "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "HPA063240: AB_2732700, HPA064557: AB_2732716" "unprognostic (1.07e-2)" "unprognostic (3.27e-3)" "unprognostic (9.52e-3)" "unprognostic (4.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.26e-4)" "unprognostic (8.94e-2)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (3.98e-8)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (4.07e-1)" "prognostic favorable (1.90e-7)" ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.2" "Cell type enhanced" "Detected in many" "Club cells: 13.5;Collecting duct cells: 11.7;Cytotrophoblasts: 15.6;Distal enterocytes: 18.2;Glandular and luminal cells: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 12.4" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;retina: 10.3;testis: 8.5" "Cell type enhanced" "Detected in some" "Astrocytes: 21.7;Excitatory neurons: 43.4;Muller glia cells: 74.3;Oligodendrocyte precursor cells: 90.1;Sertoli cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.6" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 164.8;Syncytiotrophoblasts: 318.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Golgi apparatus, Vesicles" "HPA067682: AB_2685885" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.04e-2)" "unprognostic (2.53e-1)" "unprognostic (3.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.91e-8)" "unprognostic (4.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 235.0;Distal tubular cells: 144.5;Excitatory neurons: 353.0;Inhibitory neurons: 357.7;Microglial cells: 434.8;Oligodendrocyte precursor cells: 257.1;Oligodendrocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "retina: 296.1" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 640.6;Rod photoreceptor cells: 334.9" "Cancer enriched" "Detected in single" 12 "ovarian cancer: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.3;lung cancer: 1.2;ovarian cancer: 2.2;Uterine cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 76: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA008779: AB_2668138, HPA015907: AB_2669323" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.80e-5)" "unprognostic (6.66e-4)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.59e-2)" "unprognostic (7.51e-3)" "unprognostic (1.28e-1)" "unprognostic (4.50e-9)" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (6.08e-2)" INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 208.3;Extravillous trophoblasts: 119.6;Spermatocytes: 170.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049060 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 "Nucleoli fibrillar center" "HPA049060: AB_2680617" "unprognostic (3.40e-1)" "prognostic favorable (3.58e-4)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (5.56e-2)" "unprognostic (9.68e-2)" "unprognostic (1.72e-3)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.08e-3)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-2)" "unprognostic (5.14e-3)" "unprognostic (5.38e-2)" INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 152.8;Excitatory neurons: 145.4;Inhibitory neurons: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 79.4" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Early spermatids: 156.0;Excitatory neurons: 189.6;Inhibitory neurons: 589.5;Late spermatids: 291.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA "Cluster 11: T-cells - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Neurons - Neuronal signaling" Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 76.8;Inhibitory neurons: 125.0;Late spermatids: 91.1" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "skin cancer: 74.7;testis cancer: 167.2" "Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Late spermatids - Unknown function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 118.9;thyroid gland: 198.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 17.5;Distal enterocytes: 36.3;Inhibitory neurons: 18.8;Muller glia cells: 21.7;Paneth cells: 17.0;Proximal enterocytes: 60.0" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.3" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 15 Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 547.3" "Cell type enriched" "Detected in all" 7 "Langerhans cells: 5100.7" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 273.2;non-classical monocyte: 503.5" "Lineage enriched" "Detected in all" 6 "monocytes: 503.5" "Cancer enhanced" "Detected in all" "Myeloma: 314.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 2 Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 34 "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 261.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.6" "Cancer enhanced" "Detected in all" "Myeloma: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Non-specific - Transcription" 17 "Vesicles, Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859117 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.7;testis: 1.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.2;Collecting duct cells: 1.9;Horizontal cells: 1.9;Late spermatids: 1.6;Sertoli cells: 2.7;Spermatocytes: 6.2;Spermatogonia: 1.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 31.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.5" "Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA025285 Uncertain NA NA "Cluster 78: Testis - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 2 "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" INTS1 "DKFZp586J0619, INT1, KIAA1440, NET28" ENSG00000164880 "Integrator complex subunit 1" Q8N201 7 1470277-1504389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021658, HPA053009" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Testis - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA021658: AB_1852402, HPA053009: AB_2682016" "unprognostic (3.20e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-2)" "unprognostic (2.08e-1)" "unprognostic (1.97e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (7.72e-3)" "unprognostic (3.11e-1)" "unprognostic (1.90e-2)" "prognostic favorable (4.83e-4)" "unprognostic (4.30e-1)" "unprognostic (5.10e-3)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (1.81e-3)" INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 2 "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: AB_10805710, HPA040651: AB_10796559" "unprognostic (2.92e-1)" "unprognostic (3.01e-1)" "unprognostic (2.78e-1)" "unprognostic (2.41e-1)" "unprognostic (4.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (5.60e-2)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.30e-1)" INTS2 "INT2, KIAA1287" ENSG00000108506 "Integrator complex subunit 2" Q9H0H0 17 61865367-61928016 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049524 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 2 "HPA049524: AB_2680804" "unprognostic (4.57e-3)" "unprognostic (2.11e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.72e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.52e-1)" "unprognostic (7.79e-2)" "unprognostic (5.91e-2)" "unprognostic (3.95e-1)" "unprognostic (1.85e-1)" "unprognostic (7.03e-2)" "unprognostic (1.81e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.42e-1)" IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 109.8" "Cell type enhanced" "Detected in many" "Early spermatids: 880.9;Late spermatids: 526.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 41: Basophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 21: Early spermatids - Spermatogenesis" 3 "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.7;Early spermatids: 46.9;Peritubular cells: 85.2;Sertoli cells: 35.4;Smooth muscle cells: 105.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 28: Neutrophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108335 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 51.0;lymphoid tissue: 173.5" "Cell type enhanced" "Detected in many" "B-cells: 68.1;Microglial cells: 66.2;monocytes: 60.3;NK-cells: 79.5;Plasma cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 17 "Leukemia: 162.1;lymphoma: 324.9;Myeloma: 123.7" "Breast - Endothelial cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 20: Non-specific - DNA binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" ISLR2 KIAA1465 ENSG00000167178 "Immunoglobulin superfamily containing leucine rich repeat 2" Q6UXK2 15 74100311-74138540 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.0;testis: 12.6" "Group enriched" "Detected in some" 5 "Early spermatids: 29.3;Late spermatids: 73.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 87.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Neuroblastoma: 44.6;thyroid cancer: 16.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA012930, HPA067333" Uncertain NA NA 110000 "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" 6 "HPA012930: AB_2668772, HPA067333: AB_2685824" "unprognostic (1.31e-2)" "unprognostic (3.27e-3)" "unprognostic (1.44e-2)" "unprognostic (8.65e-3)" "unprognostic (1.53e-3)" "unprognostic (7.73e-2)" "unprognostic (6.64e-2)" "unprognostic (1.46e-2)" "unprognostic (9.19e-3)" "unprognostic (1.72e-1)" "unprognostic (2.94e-2)" "unprognostic (2.46e-1)" "unprognostic (2.44e-4)" "unprognostic (1.31e-2)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 242.2;Inhibitory neurons: 273.8;Oligodendrocytes: 245.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728, HPA019752" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 28000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles, Cytosol" "HPA015590: AB_1846347, HPA019728: AB_1846348, HPA019752: " "unprognostic (6.53e-3)" "unprognostic (9.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-3)" "unprognostic (3.70e-2)" "unprognostic (9.32e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "prognostic favorable (1.95e-8)" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (4.62e-3)" ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4" "Cell type enhanced" "Detected in many" "Adipocytes: 230.2;Endothelial cells: 109.9;Hepatocytes: 85.4;Lymphatic endothelial cells: 68.4;Smooth muscle cells: 140.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain Approved "Endoplasmic reticulum" NA NA 6300000 "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Endoplasmic reticulum" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" ITGA10 ENSG00000143127 "Integrin subunit alpha 10" O75578 1 145891208-145910111 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.6;Early spermatids: 17.8;Endothelial cells: 22.9;Late spermatids: 54.6;Microglial cells: 18.8;Skeletal myocytes: 48.8" "Cancer enriched" "Detected in many" 4 "melanoma: 6.2" "Region enriched" "Detected in all" 4 "choroid plexus: 15.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 5.2;Rhabdoid: 20.0;skin cancer: 5.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA064008 Uncertain "Endoplasmic reticulum" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA064008: AB_2685173" "prognostic favorable (7.18e-4)" "unprognostic (4.53e-1)" "unprognostic (4.44e-3)" "unprognostic (2.32e-2)" "unprognostic (3.60e-2)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-1)" "unprognostic (4.37e-1)" "unprognostic (5.72e-3)" "unprognostic (6.48e-2)" "unprognostic (5.79e-2)" "unprognostic (2.58e-6)" "unprognostic (2.77e-3)" "unprognostic (1.54e-1)" "unprognostic (2.05e-5)" "unprognostic (2.57e-2)" ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.4;endometrium 1: 51.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 9.1;Cardiomyocytes: 12.5;Excitatory neurons: 12.8;Fibroblasts: 27.4;Horizontal cells: 14.5;Microglial cells: 17.9;Peritubular cells: 10.0;Smooth muscle cells: 11.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 34.8" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 9.8;spinal cord: 2.8" HPA051813 Uncertain NA NA 260000 "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA051813: AB_2681622" "unprognostic (4.85e-2)" "unprognostic (3.51e-1)" "unprognostic (6.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (9.29e-3)" "unprognostic (6.63e-2)" "unprognostic (5.68e-3)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (8.38e-3)" "unprognostic (2.28e-4)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 144.3;Basal respiratory cells: 132.7;Ductal cells: 122.3;Exocrine glandular cells: 128.5;Mucus glandular cells: 128.1;Oligodendrocytes: 345.3;Salivary duct cells: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.4;epididymis: 10.4;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Late spermatids: 26.7;Lymphatic endothelial cells: 8.9;Oligodendrocyte precursor cells: 9.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 65.1" "Lineage enriched" "Detected in single" 75 "granulocytes: 65.1" "Cancer enriched" "Detected in some" 59 "Leukemia: 83.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 279.9;Ductal cells: 113.7;Exocrine glandular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 46.0;lymphoid tissue: 72.1" "Cell type enhanced" "Detected in many" "B-cells: 97.4;Erythroid cells: 158.8;Kupffer cells: 101.2;Macrophages: 101.4;monocytes: 212.7;NK-cells: 269.6;Oocytes: 172.8;Plasma cells: 117.2;T-cells: 156.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 112.7;Myeloma: 80.8" "Adipose visceral - T-cells, Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "cerebellum: 18.6" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 4 "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 385.2;smooth muscle: 348.0;urinary bladder: 373.7" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 444.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 4: Extravillous trophoblasts - Unknown function" 4 "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 324.3;Basal keratinocytes: 228.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.5" "Group enriched" "Detected in many" 28 "granulocytes: 22.5;NK-cells: 7.3;T-cells: 12.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced NA NA 3300000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716404 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 234.2" "Group enriched" "Detected in many" 5 "Astrocytes: 83.0;Cardiomyocytes: 171.1;Sertoli cells: 54.4;Skeletal myocytes: 71.2;Smooth muscle cells: 98.7" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 22.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pancreas - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 36.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 79.7;Inhibitory neurons: 53.6;Microglial cells: 33.1;Oligodendrocyte precursor cells: 60.8;Plasma cells: 34.7;Smooth muscle cells: 106.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 13.8;Rhabdoid: 5.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.3;Inhibitory neurons: 58.4;Leydig cells: 41.9;Lymphatic endothelial cells: 72.0;Microglial cells: 51.0;Oligodendrocyte precursor cells: 87.7;Peritubular cells: 70.1;Skeletal myocytes: 45.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 10.3;testis cancer: 15.6" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" Receptor NA NA 500000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" ITGAD "ADB2, CD11d" ENSG00000156886 "Integrin subunit alpha D" Q13349 16 31393335-31426505 "CD markers, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 20.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 2.6;NK-cells: 1.3;T-cells: 1.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026786 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "HPA026786: AB_10603773" "unprognostic (2.79e-2)" "unprognostic (2.39e-4)" "unprognostic (2.88e-2)" "unprognostic (3.24e-2)" "unprognostic (6.17e-2)" "unprognostic (1.79e-2)" "unprognostic (7.44e-4)" "unprognostic (6.99e-3)" "unprognostic (6.89e-3)" "unprognostic (5.02e-4)" "unprognostic (5.50e-2)" "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (3.17e-1)" "unprognostic (8.10e-2)" "unprognostic (5.51e-2)" ITGAE "CD103, HUMINAE" ENSG00000083457 "Integrin subunit alpha E" P38570 17 3714628-3801188 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.4;intestine: 5.7;lung: 6.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 6 "T-cells: 3.7" "Group enriched" "Detected in some" 11 "Leukemia: 1.7;lymphoma: 2.5" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036313, HPA052147" Enhanced NA NA 38000 "Cluster 27: T-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" "HPA036313: AB_10795355, HPA052147: " "unprognostic (9.81e-2)" "unprognostic (1.78e-3)" "unprognostic (7.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (2.17e-1)" "unprognostic (1.45e-2)" "unprognostic (2.91e-1)" "unprognostic (8.02e-2)" "unprognostic (2.92e-2)" "unprognostic (1.10e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.34e-2)" "prognostic unfavorable (1.13e-8)" "unprognostic (8.40e-3)" "unprognostic (1.15e-1)" "unprognostic (1.82e-2)" "prognostic favorable (3.56e-4)" ITGAL "CD11A, LFA-1, LFA1A" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.5;lymphoid tissue: 63.4" "Cell type enhanced" "Detected in many" "dendritic cells: 43.0;monocytes: 180.8;NK-cells: 191.9;T-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 122.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 95 "Leukemia: 76.8;lymphoma: 43.9;Myeloma: 52.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 2 "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 180.9" "Cell type enhanced" "Detected in many" "granulocytes: 43.1;Hofbauer cells: 62.7;Kupffer cells: 121.7;Langerhans cells: 60.3;Macrophages: 85.5;Microglial cells: 39.4;NK-cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Leukemia: 11.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 34 "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590010-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 265.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.5;lung: 56.3;lymphoid tissue: 65.9" "Cell type enhanced" "Detected in some" "granulocytes: 76.6;Hofbauer cells: 70.9;Langerhans cells: 141.8;Macrophages: 125.7;monocytes: 419.8;NK-cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 7.5;lymphoma: 7.8" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Liver - Neutrophils, Skeletal muscle - Neutrophils, Thyroid - T-cells" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871, CAB080214" Enhanced Supported "Vesicles,Plasma membrane" NA NA 50000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "Vesicles, Plasma membrane" "CAB004458: AB_626859, CAB072871: AB_2665723, CAB080214: , HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Myogenesis" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1089.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 19 "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 359.1;lymphoid tissue: 167.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 750.2;Kupffer cells: 648.1;Langerhans cells: 317.3;Macrophages: 491.9;monocytes: 638.7;NK-cells: 687.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 64.2;Leukemia: 194.5;lymphoma: 74.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 21 "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 54.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 9.7;Pancreatic endocrine cells: 10.2;Proximal tubular cells: 19.4;Salivary duct cells: 14.8;Sertoli cells: 13.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "basophil: 5.6;neutrophil: 3.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 5.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 99.0;skin cancer: 125.1" "Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 38000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 57: Platelets - Hemostasis" 9 "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 194.7;skin 1: 199.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 161.2;Gastric mucus-secreting cells: 164.5;Mucus glandular cells: 163.8;Salivary duct cells: 287.3;Schwann cells: 164.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.5" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 30: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 6 "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001820, CAB022050" Approved Approved "Plasma membrane,Mitochondria" NA NA 64000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 20 "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: AB_1079142" "unprognostic (2.63e-1)" "unprognostic (1.04e-1)" "unprognostic (3.57e-1)" "unprognostic (4.44e-2)" "unprognostic (1.37e-2)" "unprognostic (6.07e-2)" "unprognostic (3.49e-3)" "unprognostic (3.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.16e-1)" "unprognostic (2.16e-3)" "unprognostic (2.49e-3)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (4.38e-3)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 66.2;skeletal muscle: 77.1;tongue: 62.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 82.9;Alveolar cells type 2: 105.6;Basal respiratory cells: 118.7;Collecting duct cells: 72.0;Ductal cells: 59.4;Exocrine glandular cells: 104.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.3" "Cell type enhanced" "Detected in many" "B-cells: 37.7;NK-cells: 95.2;Plasma cells: 104.8;Schwann cells: 32.8;T-cells: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 18 "Myeloma: 982.6" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 2 "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 447.7;Mucus glandular cells: 214.7;Oligodendrocyte precursor cells: 180.2;Salivary duct cells: 181.5;Schwann cells: 412.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 134 "basophil: 16.4" "Lineage enriched" "Detected in single" 134 "granulocytes: 16.4" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Cholangiocyte" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 314.6" "Cell type enhanced" "Detected in many" "Adipocytes: 381.8;Endothelial cells: 325.7;Fibroblasts: 267.1;granulocytes: 211.9;Leydig cells: 341.9;Muller glia cells: 217.8;Ovarian stromal cells: 195.1;T-cells: 228.3" "Cancer enhanced" "Detected in all" "glioma: 51.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 173.0;eosinophil: 88.6;gdT-cell: 107.2;MAIT T-cell: 79.4;memory CD4 T-cell: 205.2;memory CD8 T-cell: 170.3;naive CD4 T-cell: 217.2;naive CD8 T-cell: 101.8;NK-cell: 130.9;T-reg: 168.4" "Group enriched" "Detected in all" 7 "granulocytes: 173.0;NK-cells: 130.9;T-cells: 217.2" "Group enriched" "Detected in many" 8 "Bone cancer: 184.6;Leukemia: 155.6;Myeloma: 57.1;prostate cancer: 105.4" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Fibroblasts - ECM organization" 7 Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (1.05e-2)" "unprognostic (5.22e-3)" "unprognostic (2.77e-3)" "unprognostic (5.65e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-3)" "prognostic favorable (3.66e-6)" "unprognostic (1.57e-1)" "unprognostic (4.94e-2)" "unprognostic (9.85e-2)" "unprognostic (1.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.31e-1)" "unprognostic (2.18e-1)" "unprognostic (4.30e-1)" ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4399.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 4399.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 5800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Non-specific - Transcription" 8 "Golgi apparatus, Vesicles" "HPA029292: AB_10601917, HPA071992: AB_2686480" "unprognostic (4.66e-2)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" "unprognostic (4.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-2)" "prognostic favorable (3.73e-5)" "unprognostic (4.38e-2)" "unprognostic (4.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847506 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 280.6;Inhibitory neurons: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 273.5" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 8: Neurons - Neuronal signaling" 3 Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.0" "Cell type enhanced" "Detected in many" "Astrocytes: 523.0;Excitatory neurons: 278.0;Microglial cells: 766.7;Oligodendrocyte precursor cells: 414.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "Endoplasmic reticulum" Nucleoplasm "HPA059144: AB_2683925, HPA062260: AB_2684728" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 80.4;Gastric mucus-secreting cells: 115.0;Late spermatids: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" 2 Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 201.0" "Cell type enhanced" "Detected in many" "Adipocytes: 95.0;Basal squamous epithelial cells: 80.9;Squamous epithelial cells: 145.4;Suprabasal keratinocytes: 93.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" 3 Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" ITPRIPL2 "FLJ22994, LOC162073, MGC126798, MGC126800" ENSG00000205730 "ITPRIP like 2" Q3MIP1 16 19113932-19121629 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042011 Approved Centrosome NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 21: Testis - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" Centrosome "HPA042011: AB_2677795" "unprognostic (1.07e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (9.64e-2)" "unprognostic (1.97e-1)" "unprognostic (2.20e-1)" "unprognostic (3.76e-2)" "unprognostic (6.72e-3)" "unprognostic (5.60e-2)" "unprognostic (1.90e-2)" "unprognostic (5.26e-3)" "unprognostic (4.24e-2)" "unprognostic (1.53e-1)" "unprognostic (7.23e-2)" "unprognostic (6.37e-2)" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 206.2;Inhibitory neurons: 145.8;Rod photoreceptor cells: 134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" 14 "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 458.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.4;Distal enterocytes: 19.9;Hepatocytes: 24.3;Intestinal goblet cells: 27.4;Paneth cells: 17.1;Proximal enterocytes: 76.2;Proximal tubular cells: 28.7" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 2.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" IZUMO1 "IZUMO, MGC34799, OBF" ENSG00000182264 "Izumo sperm-egg fusion 1" Q8IYV9 19 48740852-48746909 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 18.4" "Group enriched" "Detected in some" 35 "Early spermatids: 146.4;Late spermatids: 126.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Vascular Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038104 Enhanced NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 13: Spermatids - Transcription" "HPA038104: AB_10670655" "unprognostic (2.03e-1)" "unprognostic (1.86e-3)" "unprognostic (3.73e-2)" "unprognostic (1.37e-2)" "unprognostic (1.17e-2)" "unprognostic (7.92e-2)" "unprognostic (3.49e-2)" "unprognostic (2.53e-4)" "unprognostic (3.61e-2)" "unprognostic (1.69e-2)" "unprognostic (1.45e-1)" "unprognostic (4.83e-2)" "unprognostic (1.32e-2)" "unprognostic (3.68e-1)" "unprognostic (2.92e-1)" "unprognostic (4.31e-3)" "unprognostic (6.92e-2)" IZUMO2 "C19orf41, MGC33947, SCRL" ENSG00000161652 "IZUMO family member 2" Q6UXV1 19 50152548-50163281 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 425 "testis: 62.8" "Group enriched" "Detected in some" 97 "Early spermatids: 722.3;Late spermatids: 427.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042143 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 11: Late spermatids - Unknown function" "HPA042143: AB_10794078" "unprognostic (1.21e-2)" "unprognostic (3.18e-2)" "unprognostic (4.31e-2)" "unprognostic (1.81e-1)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (8.75e-2)" JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 260.8;Smooth muscle cells: 167.8;Squamous epithelial cells: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 29: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 50.3;Basal respiratory cells: 29.6;Breast myoepithelial cells: 30.2;Endothelial cells: 33.6;Salivary duct cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Prostate basal glandular cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 21: Testis - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" JAGN1 "FLJ14602, GL009" ENSG00000171135 "Jagunal homolog 1" Q8N5M9 3 9890574-9894349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" HPA067610 Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 102 Vesicles "HPA067610: " "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-3)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (2.37e-2)" "unprognostic (6.36e-3)" "unprognostic (9.93e-3)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" JAKMIP1 "FLJ31564, Gababrbp, JAMIP1, MARLIN1" ENSG00000152969 "Janus kinase and microtubule interacting protein 1" Q96N16 4 6026199-6200591 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 69.6" "Group enriched" "Detected in some" 5 "Astrocytes: 33.8;Excitatory neurons: 80.1;Inhibitory neurons: 51.3;Muller glia cells: 42.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "gdT-cell: 25.1;MAIT T-cell: 11.0;memory CD4 T-cell: 10.9;memory CD8 T-cell: 22.3;naive CD8 T-cell: 9.9;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Group enriched" "Detected in some" 4 "Leukemia: 4.9;lung cancer: 3.0;lymphoma: 10.0;Myeloma: 9.4;Neuroblastoma: 8.0" "Adipose subcutaneous - T-cells, Colon - Colon enteroendocrine cells, Liver - T-cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044570 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Neurons - Neuronal signaling" 14 "HPA044570: AB_2678995" "unprognostic (4.79e-2)" "unprognostic (3.46e-3)" "unprognostic (4.90e-2)" "unprognostic (1.73e-2)" "unprognostic (5.34e-2)" "unprognostic (3.86e-3)" "unprognostic (6.16e-2)" "unprognostic (6.69e-3)" "unprognostic (4.25e-4)" "unprognostic (7.14e-2)" "unprognostic (4.57e-3)" "unprognostic (1.13e-1)" "unprognostic (3.70e-8)" "unprognostic (1.85e-2)" "unprognostic (3.15e-1)" "unprognostic (4.23e-2)" "unprognostic (2.96e-3)" JAKMIP2 "JAMIP2, KIAA0555" ENSG00000176049 "Janus kinase and microtubule interacting protein 2" Q96AA8 5 147585438-147782775 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.8;pituitary gland: 8.1" "Group enriched" "Detected in many" 5 "Astrocytes: 185.5;Excitatory neurons: 242.2;Horizontal cells: 62.9;Inhibitory neurons: 219.6;Oligodendrocyte precursor cells: 149.5;Oligodendrocytes: 184.7" "Cancer enriched" "Detected in some" 6 "glioma: 4.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;MAIT T-cell: 5.3;memory CD4 T-cell: 2.8;memory CD8 T-cell: 5.5;naive CD8 T-cell: 4.6;NK-cell: 7.0" "Group enriched" "Detected in many" 6 "NK-cells: 7.0;T-cells: 7.3" "Cancer enhanced" "Detected in many" "Bone cancer: 24.7" "Kidney - Podocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046929, HPA065023" Approved Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 16: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 13 "Golgi apparatus" "HPA046929: AB_2679867, HPA065023: AB_2685407" "unprognostic (3.69e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (3.58e-2)" "unprognostic (1.63e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.21e-4)" "unprognostic (1.28e-1)" "unprognostic (5.20e-8)" "unprognostic (1.54e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" JAKMIP3 "bA140A10.5, C10orf14, C10orf39, FLJ37857, KIAA4091, NECC2" ENSG00000188385 "Janus kinase and microtubule interacting protein 3" Q5VZ66 10 132036336-132184858 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;pituitary gland: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 13.6;Excitatory neurons: 38.0;Inhibitory neurons: 31.0;Oligodendrocyte precursor cells: 25.5;Oligodendrocytes: 86.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022872 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Oligodendrocytes - Unknown function" "HPA022872: AB_2249331" "unprognostic (1.75e-1)" "unprognostic (1.76e-2)" "unprognostic (4.55e-3)" "unprognostic (8.90e-2)" "unprognostic (2.72e-1)" "unprognostic (9.39e-2)" "unprognostic (2.31e-3)" "unprognostic (1.40e-1)" "unprognostic (2.22e-1)" "unprognostic (1.80e-1)" "unprognostic (5.28e-5)" "unprognostic (1.55e-2)" "unprognostic (5.71e-6)" "unprognostic (1.43e-1)" "unprognostic (2.11e-1)" "unprognostic (7.19e-4)" "unprognostic (1.59e-2)" JAM2 "C21orf43, CD322, JAM-2, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.4" "Cell type enhanced" "Detected in many" "Adipocytes: 184.4;Astrocytes: 77.4;Endothelial cells: 131.1;Microglial cells: 78.7;Oligodendrocyte precursor cells: 72.2" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.7;Rhabdoid: 8.5" "Adipose subcutaneous - Endothelial cells, Colon - Enteric glia cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" JAM3 "JAM-3, JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 81.5;Extravillous trophoblasts: 77.5;Oligodendrocyte precursor cells: 71.7;Oligodendrocytes: 319.1;Rod photoreceptor cells: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.4" "Low cancer specificity" "Detected in many" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" "Cell adhesion" NA NA 44000 "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 41.9;lymphoid tissue: 66.8" "Cell type enhanced" "Detected in many" "dendritic cells: 271.2;Hofbauer cells: 104.0;Kupffer cells: 116.2;Langerhans cells: 328.1;Macrophages: 141.9;monocytes: 73.9;T-cells: 86.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in all" "eosinophil: 3539.1" "Group enriched" "Detected in all" 5 "dendritic cells: 1018.9;granulocytes: 3539.1;monocytes: 1025.5" "Group enriched" "Detected in some" 11 "Leukemia: 7.5;lymphoma: 18.0" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 63.6" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Thyroid gland - Unknown function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Mixed function" Vesicles Nucleoplasm "HPA031172: AB_10670563, HPA071650: AB_2686429" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (4.95e-2)" "unprognostic (5.88e-2)" "unprognostic (2.54e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.09e-6)" "unprognostic (2.68e-1)" "unprognostic (3.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (3.14e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.73e-1)" JPH1 JP-1 ENSG00000104369 "Junctophilin 1" Q9HDC5 8 74234700-74321540 "Human disease related genes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 228.9;tongue: 102.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 33.1;Excitatory neurons: 79.4;Inhibitory neurons: 48.3;Skeletal myocytes: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008996, HPA009413, CAB013461" Enhanced Enhanced Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 10 Nucleoplasm "CAB013461: , HPA008996: AB_1852023, HPA009413: AB_1079163" "unprognostic (2.91e-3)" "unprognostic (3.01e-1)" "unprognostic (8.85e-2)" "unprognostic (8.73e-6)" "unprognostic (2.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.63e-2)" "prognostic favorable (5.77e-5)" "unprognostic (8.97e-2)" "unprognostic (1.30e-1)" "unprognostic (2.38e-1)" "unprognostic (5.99e-2)" "unprognostic (9.80e-2)" "unprognostic (6.87e-2)" "unprognostic (3.03e-1)" "unprognostic (4.88e-2)" "unprognostic (1.08e-2)" JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 82.4;skeletal muscle: 116.1" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 69.5;Oocytes: 39.7;Skeletal myocytes: 66.4;Smooth muscle cells: 27.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" JPH3 "CAGL237, HDL2, JP-3, JP3, TNRC22" ENSG00000154118 "Junctophilin 3" Q8WXH2 16 87601835-87698156 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 125.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 26.2;Cone photoreceptor cells: 15.3;Early spermatids: 32.8;Excitatory neurons: 32.1;Horizontal cells: 25.8;Inhibitory neurons: 27.4;Late spermatids: 26.0;Oocytes: 42.6" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 5.8;Neuroblastoma: 6.1" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" HPA076304 Approved Nucleoplasm,Cytosol Yes No "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" 146 Nucleoplasm Cytosol "HPA076304: AB_2686793" "unprognostic (8.97e-3)" "unprognostic (3.17e-2)" "unprognostic (1.57e-3)" "unprognostic (4.82e-3)" "unprognostic (3.43e-1)" "unprognostic (9.12e-2)" "unprognostic (1.68e-2)" "unprognostic (8.10e-2)" "unprognostic (5.53e-2)" "unprognostic (1.48e-1)" "unprognostic (5.61e-3)" "unprognostic (2.80e-2)" "unprognostic (1.28e-4)" "unprognostic (3.01e-2)" "unprognostic (2.09e-1)" "unprognostic (1.87e-2)" "unprognostic (1.36e-2)" JPH4 "JPHL1, KIAA1831" ENSG00000092051 "Junctophilin 4" Q96JJ6 14 23568038-23578790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.7;seminal vesicle: 31.0" "Group enriched" "Detected in some" 13 "Bipolar cells: 141.8;Horizontal cells: 449.4" "Cancer enhanced" "Detected in some" "glioma: 6.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 3.1;monocytes: 2.7" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 43.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045022 Approved Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 Cytosol "HPA045022: " "unprognostic (3.30e-2)" "unprognostic (1.91e-3)" "unprognostic (5.05e-3)" "unprognostic (7.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.84e-1)" "unprognostic (3.77e-3)" "unprognostic (5.98e-4)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (3.89e-3)" "unprognostic (1.15e-2)" "unprognostic (3.15e-2)" "unprognostic (2.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.13e-2)" "unprognostic (4.96e-3)" JTB "hJT, PAR" ENSG00000143543 "Jumping translocation breakpoint" O76095 1 153974269-153977674 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006514 Approved Uncertain Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA006514: AB_1079164" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (8.01e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.40e-1)" "unprognostic (5.66e-3)" "unprognostic (8.62e-3)" "unprognostic (5.60e-2)" "prognostic favorable (7.87e-4)" "unprognostic (1.00e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (1.36e-1)" "unprognostic (4.25e-1)" "unprognostic (5.48e-2)" "unprognostic (2.58e-3)" KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124033369-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1386.1;Inhibitory neurons: 459.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 83000 "Cluster 54: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Neurons - Neuronal signaling" 2 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" KANSL1L "C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2" ENSG00000144445 "KAT8 regulatory NSL complex subunit 1 like" A0AUZ9 2 210021421-210171409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 192.4" "Cell type enhanced" "Detected in all" "Astrocytes: 107.8;Inhibitory neurons: 113.2;Microglial cells: 98.4;Oligodendrocyte precursor cells: 178.8;Oligodendrocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043102, HPA046790" Uncertain Approved Cytosol NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" Cytosol "HPA043102: AB_2678316, HPA046790: AB_2679808" "unprognostic (3.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-3)" "unprognostic (1.45e-2)" "unprognostic (2.55e-3)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (5.99e-3)" "unprognostic (4.65e-2)" "unprognostic (5.89e-3)" "unprognostic (5.75e-2)" "unprognostic (5.95e-3)" "unprognostic (7.44e-2)" "unprognostic (4.60e-2)" "unprognostic (3.21e-2)" "unprognostic (1.30e-3)" KASH5 "CCDC155, FLJ32658" ENSG00000161609 "KASH domain containing 5" Q8N6L0 19 49388219-49417990 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 53.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 32.4;Early spermatids: 23.6;Late spermatids: 11.4;Spermatocytes: 96.3;Spermatogonia: 17.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enriched" "Detected in single" 10 "cerebellum: 8.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 5.2" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA019937, HPA019940" Enhanced NA NA "Cluster 78: Testis - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 31: Spermatocytes - Spermatogenesis" 96 "HPA019937: AB_1848877, HPA019940: AB_1848879" "unprognostic (1.31e-1)" "unprognostic (4.23e-2)" "unprognostic (2.28e-2)" "unprognostic (1.09e-2)" "unprognostic (3.99e-1)" "unprognostic (1.79e-1)" "unprognostic (6.41e-2)" "unprognostic (5.31e-2)" "unprognostic (8.96e-2)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" "unprognostic (2.57e-1)" "unprognostic (7.11e-9)" "unprognostic (6.50e-2)" "unprognostic (4.18e-1)" "unprognostic (3.08e-3)" "unprognostic (1.20e-3)" KCNA1 "AEMK, HUK1, Kv1.1, MBK1, RBK1" ENSG00000111262 "Potassium voltage-gated channel subfamily A member 1" Q09470 12 4909905-4918256 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "brain: 52.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.8;Excitatory neurons: 38.3;Horizontal cells: 21.4;Inhibitory neurons: 17.9;Oligodendrocyte precursor cells: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074471 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA074471: " "unprognostic (6.39e-3)" "unprognostic (2.64e-1)" "unprognostic (1.09e-1)" "unprognostic (8.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-2)" "unprognostic (4.69e-3)" "unprognostic (2.48e-1)" "unprognostic (8.77e-5)" "unprognostic (6.30e-2)" "unprognostic (1.08e-4)" KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 32.1;retina: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 47.4;Early spermatids: 16.9;Excitatory neurons: 35.5;Horizontal cells: 33.4;Inhibitory neurons: 35.6;Muller glia cells: 15.6;Oligodendrocyte precursor cells: 34.0" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Group enriched" "Detected in some" 5 "Bone cancer: 8.0;Myeloma: 3.0" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 1 "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110653560-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lung: 2.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 12.7;Inhibitory neurons: 57.6;Plasma cells: 49.8;T-cells: 24.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 5.6;MAIT T-cell: 5.3;memory CD4 T-cell: 8.5;memory CD8 T-cell: 9.6;naive B-cell: 2.6;naive CD4 T-cell: 5.0;naive CD8 T-cell: 4.6;T-reg: 8.5" "Group enriched" "Detected in many" 6 "B-cells: 2.6;T-cells: 9.6" "Cancer enriched" "Detected in some" 5 "Myeloma: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Skin - T-cells, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 2 "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4, PCN2" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.9;brain: 7.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.7;Cardiomyocytes: 3.5;Excitatory neurons: 7.9;Horizontal cells: 6.9;Mesothelial cells: 6.8;Muller glia cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001977, HPA016422" Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 3 "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043879-5046788 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 59.0;heart muscle: 38.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 128.0;Cardiomyocytes: 21.5;dendritic cells: 18.9;Horizontal cells: 34.0;Smooth muscle cells: 29.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Region enriched" "Detected in all" 7 "choroid plexus: 113.8" "Immune cell enriched" "Detected in single" 122 "plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 122 "dendritic cells: 12.2" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021516, CAB022562" Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" 2 "CAB022562: , HPA021516: AB_2670732" "unprognostic (3.87e-1)" "unprognostic (9.91e-3)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (7.06e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (5.08e-3)" "unprognostic (6.73e-4)" "unprognostic (1.92e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (3.08e-2)" KCNA6 "HBK2, Kv1.6, PPP1R96" ENSG00000151079 "Potassium voltage-gated channel subfamily A member 6" P17658 12 4809334-4813318 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 9.4" "Group enriched" "Detected in some" 8 "Astrocytes: 13.3;Excitatory neurons: 26.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 2.3;testis cancer: 7.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076475 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" Vesicles "HPA076475: " KCNA7 "HAK6, Kv1.7" ENSG00000104848 "Potassium voltage-gated channel subfamily A member 7" Q96RP8 19 49067397-49072699 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 53 "skeletal muscle: 76.8;tongue: 19.8" "Cell type enriched" "Detected in some" 33 "Skeletal myocytes: 57.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075990 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "HPA075990: " "unprognostic (2.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.72e-1)" "unprognostic (1.68e-1)" "unprognostic (4.31e-2)" "unprognostic (3.17e-2)" "unprognostic (6.97e-2)" "unprognostic (2.94e-2)" "unprognostic (1.26e-1)" "unprognostic (2.21e-8)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (5.80e-2)" "unprognostic (5.29e-2)" KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 111.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.9;Cone photoreceptor cells: 309.2;Excitatory neurons: 145.6;Inhibitory neurons: 85.9;Rod photoreceptor cells: 352.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5;Rhabdoid: 4.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;lymphoid tissue: 2.2;retina: 4.4" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 178.4;Excitatory neurons: 269.5;Inhibitory neurons: 230.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 102.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Excitatory neurons: 46.6;Horizontal cells: 272.6;Inhibitory neurons: 115.5" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" KCNC2 Kv3.2 ENSG00000166006 "Potassium voltage-gated channel subfamily C member 2" Q96PR1 12 75040077-75209839 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.8" "Group enriched" "Detected in some" 10 "Excitatory neurons: 377.2;Inhibitory neurons: 1368.9" "Group enriched" "Detected in some" 8 "breast cancer: 1.5;prostate cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;Sarcoma: 1.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019664, CAB022571" Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "CAB022571: , HPA019664: AB_1855578" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (5.58e-3)" "unprognostic (4.46e-2)" "unprognostic (3.39e-2)" KCNC3 "Kv3.3, SCA13" ENSG00000131398 "Potassium voltage-gated channel subfamily C member 3" Q14003 19 50311937-50333515 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.2;thyroid gland: 50.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 19.4;Excitatory neurons: 15.1;Glandular and luminal cells: 14.9;Inhibitory neurons: 17.6;monocytes: 16.5;Secretory cells: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018041 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA018041: AB_1855579" "unprognostic (8.05e-2)" "unprognostic (2.34e-2)" "unprognostic (3.01e-4)" "unprognostic (4.41e-2)" "unprognostic (3.84e-2)" "unprognostic (1.91e-2)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (3.94e-3)" "unprognostic (2.10e-5)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-2)" "unprognostic (1.19e-1)" KCNC4 "C1orf30, HKSHIIIC, Kv3.4" ENSG00000116396 "Potassium voltage-gated channel subfamily C member 4" Q03721 1 110210314-110283100 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 43.2;Sertoli cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014740 Approved Nucleoli,Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nucleoli, Cytosol" "HPA014740: AB_1855580" "unprognostic (9.16e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-2)" "unprognostic (3.72e-1)" "unprognostic (4.12e-2)" "unprognostic (6.13e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (2.03e-1)" "unprognostic (4.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.25e-2)" KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;Peritubular cells: 4.0;Rod photoreceptor cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA000524: AB_2666013, HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favorable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273175-120750337 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 36.3" "Group enriched" "Detected in some" 11 "Excitatory neurons: 667.4;Inhibitory neurons: 1026.1;Oligodendrocyte precursor cells: 1832.4" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.9" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA029068: AB_10601436" "unprognostic (4.22e-1)" "unprognostic (2.79e-4)" "unprognostic (3.79e-2)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-3)" "unprognostic (9.07e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.77e-3)" "unprognostic (1.51e-1)" "unprognostic (4.51e-4)" "unprognostic (4.07e-5)" "unprognostic (2.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.83e-3)" KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.6;Cardiomyocytes: 36.9;Excitatory neurons: 102.1;Hepatocytes: 32.7;Horizontal cells: 40.9;Inhibitory neurons: 84.6;Late spermatids: 34.4;Oligodendrocyte precursor cells: 42.9" "Cancer enhanced" "Detected in many" "prostate cancer: 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" KCNE2 "LQT6, MiRP1" ENSG00000159197 "Potassium voltage-gated channel subfamily E regulatory subunit 2" Q9Y6J6 21 34364006-34371381 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "stomach 1: 307.7" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 136.2" "Cancer enriched" "Detected in some" 6 "stomach cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "pons and medulla: 29.0" "Not detected" "Not detected" "HPA029706, HPA051553" Enhanced NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA029706: AB_2673159, HPA051553: AB_2681532" "unprognostic (5.29e-4)" "unprognostic (3.13e-1)" "unprognostic (6.69e-2)" "unprognostic (2.65e-5)" "unprognostic (7.45e-2)" "unprognostic (7.33e-3)" "unprognostic (5.77e-3)" "unprognostic (6.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.33e-2)" "unprognostic (9.30e-2)" "unprognostic (3.41e-2)" "unprognostic (2.19e-3)" "unprognostic (1.48e-1)" "unprognostic (3.97e-2)" "unprognostic (2.02e-1)" "unprognostic (8.81e-2)" KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 68.4;stomach 1: 54.6" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 43.6;Hofbauer cells: 48.7;Kupffer cells: 110.2;Macrophages: 36.9;monocytes: 50.3;Undifferentiated cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 49 "basophil: 51.7;classical monocyte: 38.6;eosinophil: 23.5;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.4;non-classical monocyte: 36.8" "Group enriched" "Detected in many" 123 "dendritic cells: 18.3;granulocytes: 53.4;monocytes: 41.8" "Cancer enhanced" "Detected in many" "Bone cancer: 68.1;cervical cancer: 61.1" "Adipose subcutaneous - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014849 Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" KCNE4 MiRP3 ENSG00000152049 "Potassium voltage-gated channel subfamily E regulatory subunit 4" Q8WWG9 2 223052190-223198399 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.5;Melanocytes: 67.0;Muller glia cells: 23.2;Sertoli cells: 38.1;Smooth muscle cells: 91.1" "Cancer enhanced" "Detected in all" "breast cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 45.4" "Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011420 Approved Approved "Nuclear bodies,Microtubules" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" 2 Microtubules "Nuclear bodies" "HPA011420: AB_1079170" "unprognostic (1.23e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.42e-5)" "unprognostic (2.17e-2)" "unprognostic (7.56e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" "unprognostic (6.24e-3)" "unprognostic (9.08e-3)" KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "brain: 46.8;choroid plexus: 24.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.0;Extravillous trophoblasts: 17.6;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 17.0;Syncytiotrophoblasts: 7.5" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 11.5;lung cancer: 9.0" "Breast - Breast glandular cells (progenitors), Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 9 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "endometrium 1: 84.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.0;Early spermatids: 19.2;Late spermatids: 21.2;Syncytiotrophoblasts: 82.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 72 "B-cells: 7.1" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 17.3;basal ganglia: 15.0;cerebral cortex: 29.9;hippocampal formation: 22.6" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79797938-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.0" "Cell type enhanced" "Detected in some" "dendritic cells: 28.0;Excitatory neurons: 18.6;Horizontal cells: 27.1;Inhibitory neurons: 29.9;Oocytes: 75.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "hippocampal formation: 24.5" HPA048628 Enhanced NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 69: Neurons - Neuronal signaling" "HPA048628: AB_2680466" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-1)" "unprognostic (1.99e-1)" "unprognostic (9.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (3.78e-1)" "unprognostic (3.61e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-5)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" KCNG3 Kv6.3 ENSG00000171126 "Potassium voltage-gated channel modifier subfamily G member 3" Q8TAE7 2 42442017-42493982 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 15.8;Glandular and luminal cells: 10.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 7.1" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041625 Approved "Cytoplasmic bodies" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Cytoplasmic bodies" "HPA041625: " "unprognostic (1.56e-1)" "unprognostic (4.22e-3)" "unprognostic (2.48e-1)" "unprognostic (7.67e-3)" "unprognostic (7.95e-2)" "unprognostic (9.14e-3)" "unprognostic (4.83e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (2.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (2.76e-1)" "unprognostic (6.47e-2)" "unprognostic (1.23e-1)" KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218657-84240012 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "retina: 3.8" "Cell type enriched" "Detected in some" 10 "Bipolar cells: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA063516: " "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 516.4;Inhibitory neurons: 249.8;Oligodendrocytes: 108.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Adrenocortical cancer: 20.7" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;retina: 4.3" "Group enriched" "Detected in some" 11 "Bipolar cells: 47.3;Excitatory neurons: 178.8;Horizontal cells: 51.0;Inhibitory neurons: 71.0;Oligodendrocyte precursor cells: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;cervical cancer: 1.2" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Centrosome "Nucleoplasm, Cytosol" "HPA030487: AB_10609995, HPA072351: " "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (8.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.7;kidney: 6.8;pituitary gland: 5.2;prostate: 3.8;retina: 4.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.1;Cone photoreceptor cells: 11.9;Enteroendocrine cells: 27.3;Horizontal cells: 11.3;Prostatic glandular cells: 24.5;Proximal enterocytes: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.2;lung cancer: 9.7;prostate cancer: 5.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.4;olfactory bulb: 3.2;spinal cord: 3.2" HPA061704 Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838767 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;retina: 1.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 663.4;Inhibitory neurons: 337.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 5 "amygdala: 21.6;cerebral cortex: 85.1;hippocampal formation: 55.9;olfactory bulb: 53.9" HPA018039 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA018039: AB_1852125" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.66e-1)" "unprognostic (5.55e-2)" "unprognostic (3.05e-2)" "unprognostic (5.51e-2)" "unprognostic (8.12e-3)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.55e-3)" "unprognostic (2.76e-3)" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.68e-2)" KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;pituitary gland: 10.4;retina: 3.3" "Group enriched" "Detected in many" 39 "Oligodendrocyte precursor cells: 311.3;Oligodendrocytes: 921.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.0;Neuroblastoma: 2.4" "Colon - Enteric glia cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.7;retina: 17.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9498.4;Inhibitory neurons: 1881.5;Oligodendrocyte precursor cells: 4856.7" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Kidney - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 5 Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" KCNJ1 "Kir1.1, ROMK1" ENSG00000151704 "Potassium inwardly rectifying channel subfamily J member 1" P48048 11 128836315-128867373 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Bartter syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "kidney: 191.1" "Group enriched" "Detected in some" 96 "Collecting duct cells: 23.3;Distal tubular cells: 79.9" "Cancer enriched" "Detected in some" 7 "renal cancer: 3.4" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA026962 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA026962: AB_10601934" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-1)" "unprognostic (2.44e-2)" "unprognostic (6.47e-2)" "unprognostic (2.78e-1)" "unprognostic (6.05e-2)" "unprognostic (4.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (7.81e-3)" KCNJ10 "Kir1.2, Kir4.1" ENSG00000177807 "Potassium inwardly rectifying channel subfamily J member 10" P78508 1 159998651-160070160 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 113.7;kidney: 27.0;retina: 35.6" "Group enriched" "Detected in some" 7 "Astrocytes: 88.2;Muller glia cells: 66.1;Oligodendrocyte precursor cells: 33.5;Oligodendrocytes: 87.3" "Cancer enriched" "Detected in some" 6 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 2.0" "Kidney - Ascending Loop of Henle cells, Liver - Kupffer cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078302 Enhanced NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" 2 "HPA078302: AB_2732378" "unprognostic (2.64e-2)" "unprognostic (3.54e-3)" "unprognostic (6.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (6.98e-4)" "unprognostic (1.96e-1)" "unprognostic (7.13e-2)" "unprognostic (3.43e-1)" "unprognostic (1.28e-3)" "unprognostic (5.80e-4)" "unprognostic (9.52e-2)" "unprognostic (2.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "unprognostic (6.70e-3)" KCNJ11 "BIR, Kir6.2" ENSG00000187486 "Potassium inwardly rectifying channel subfamily J member 11" Q14654 11 17365172-17389331 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 129.9;tongue: 41.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 7.8;Cardiomyocytes: 19.5;Enteroendocrine cells: 6.3;Inhibitory neurons: 5.7;Skeletal myocytes: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048891 Approved NA NA "Cluster 79: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "HPA048891: AB_2680547" "unprognostic (1.95e-2)" "unprognostic (6.18e-3)" "unprognostic (7.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (4.81e-5)" "unprognostic (1.83e-3)" "unprognostic (5.45e-2)" "unprognostic (8.09e-3)" "unprognostic (3.72e-3)" "unprognostic (9.23e-3)" "prognostic favorable (1.56e-4)" "unprognostic (4.05e-2)" "unprognostic (2.10e-2)" "unprognostic (1.67e-1)" "unprognostic (4.75e-2)" KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 41.5;skeletal muscle: 66.7;tongue: 24.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.2;Horizontal cells: 30.2;Muller glia cells: 9.1;Skeletal myocytes: 19.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Skeletal muscle - Skeletal myocytes" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 170.7;intestine: 88.7" "Cell type enhanced" "Detected in some" "Melanocytes: 29.2;Muller glia cells: 52.0;Proximal enterocytes: 219.0;Undifferentiated cells: 65.7" "Cancer enriched" "Detected in some" 5 "melanoma: 5.9" "Region enriched" "Detected in all" 15 "choroid plexus: 342.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.1" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" "Nuclear membrane" "HPA051609: " "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "unprognostic (9.03e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (1.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 232.9;thyroid gland: 125.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 86.7;Cholangiocytes: 87.8;Early spermatids: 141.5;Late spermatids: 77.7;Proximal tubular cells: 198.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "neutrophil: 398.0" "Lineage enriched" "Detected in many" 21 "granulocytes: 398.0" "Cancer enhanced" "Detected in many" "Bladder cancer: 22.2;head and neck cancer: 20.7" "Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 188.3;parathyroid gland: 258.5;thyroid gland: 135.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 29.2;Cholangiocytes: 45.8;Collecting duct cells: 196.4;Distal tubular cells: 43.0;Oligodendrocyte precursor cells: 51.4;Proximal tubular cells: 87.4" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 26.7;Sarcoma: 16.6" "Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" KCNJ18 "KIR2.6, TTPP2" ENSG00000260458 "Potassium inwardly rectifying channel subfamily J member 18" B7U540 17 21692523-21704612 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 7.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 0.8;head and neck cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027021 Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Late spermatids - Unknown function" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (2.41e-1)" "unprognostic (3.90e-5)" "unprognostic (2.56e-1)" "unprognostic (1.95e-1)" KCNJ2 "IRK1, Kir2.1, LQT7" ENSG00000123700 "Potassium inwardly rectifying channel subfamily J member 2" P63252 17 70168673-70180044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 34.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.3;Horizontal cells: 61.1;monocytes: 61.8;Oligodendrocytes: 153.3;Skeletal myocytes: 36.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.3" "Liver - Kupffer cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029109 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 7 "HPA029109: AB_10602913" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (3.50e-1)" "unprognostic (6.36e-3)" "unprognostic (1.22e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.74e-3)" "unprognostic (6.15e-3)" "unprognostic (9.60e-3)" "unprognostic (4.89e-2)" "unprognostic (5.49e-3)" KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.5" "Group enriched" "Detected in many" 5 "Excitatory neurons: 299.2;Inhibitory neurons: 413.7" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 62.3;pancreas: 19.8" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 54.8;Hofbauer cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Skin - Fibroblast_1" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 69.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 20.2;Cardiomyocytes: 24.1;Granulosa cells: 19.5;Hepatocytes: 22.8;Muller glia cells: 20.3;Sertoli cells: 73.4;Smooth muscle cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.8;liver cancer: 7.0;Neuroblastoma: 11.5" "Breast - Endothelial cells, Kidney - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031066 Uncertain NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 34: Testis cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 3 "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" KCNJ9 "GIRK3, Kir3.3" ENSG00000162728 "Potassium inwardly rectifying channel subfamily J member 9" Q92806 1 160081538-160090563 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 72.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Excitatory neurons: 22.7;Horizontal cells: 15.7;Inhibitory neurons: 12.0;Oligodendrocytes: 7.7" "Cancer enriched" "Detected in single" 35 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 3.6" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070478 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA070478: AB_2686270" "unprognostic (2.35e-1)" "unprognostic (6.53e-2)" "unprognostic (2.17e-2)" "unprognostic (4.73e-1)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (1.66e-1)" "unprognostic (3.33e-2)" "unprognostic (2.64e-1)" "unprognostic (3.29e-1)" "unprognostic (3.44e-1)" "unprognostic (1.49e-1)" "unprognostic (1.84e-2)" "unprognostic (2.66e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (5.24e-2)" KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.9;choroid plexus: 72.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 160.5" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 5: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;intestine: 4.9;stomach 1: 2.5" "Cell type enhanced" "Detected in some" "dendritic cells: 51.3;Excitatory neurons: 42.4;Inhibitory neurons: 16.3;Oligodendrocyte precursor cells: 35.4;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.3;parathyroid gland: 5.8;testis: 9.0" "Cell type enriched" "Detected in some" 4 "Microglial cells: 39.4" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cancer enhanced" "Detected in single" "testis cancer: 2.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 14: Langerhans cells - Innate immune response" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" KCNK15 "dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5" ENSG00000124249 "Potassium two pore domain channel subfamily K member 15" Q9H427 20 44745865-44752313 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Mesothelial cells: 43.8;Secretory cells: 104.5" "Cancer enriched" "Detected in many" 7 "ovarian cancer: 47.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 18 "olfactory bulb: 6.8" "Region enriched" "Detected in single" 8 "olfactory bulb: 5.1" HPA064861 Uncertain NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA064861: AB_2685373" "unprognostic (8.70e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.05e-2)" "unprognostic (2.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.50e-2)" "unprognostic (4.22e-2)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (4.60e-2)" "unprognostic (6.27e-2)" "unprognostic (6.11e-2)" "unprognostic (7.38e-4)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (2.21e-3)" "unprognostic (2.11e-1)" KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.5;thyroid gland: 6.3" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Microglial cells: 17.0;Pancreatic endocrine cells: 18.7;Smooth muscle cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.9" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6;thyroid cancer: 3.4" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" KCNK18 "K2p18.1, TRESK, TRESK-2, TRESK2, TRIK" ENSG00000186795 "Potassium two pore domain channel subfamily K member 18" Q7Z418 10 117197489-117210299 "Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "choroid plexus: 2.9;hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044739 Uncertain NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" "HPA044739: AB_10795008" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.4;kidney: 36.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.4;Cytotrophoblasts: 28.2;Distal enterocytes: 43.4;Proximal enterocytes: 55.6;Salivary duct cells: 34.9;Syncytiotrophoblasts: 40.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 24 Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 130.8;Suprabasal keratinocytes: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.3;granulocytes: 26.2;monocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: AB_2676876" "unprognostic (7.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.45e-6)" "unprognostic (3.76e-1)" "unprognostic (6.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.08e-2)" "unprognostic (4.31e-1)" "unprognostic (4.91e-1)" "unprognostic (4.10e-3)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.07e-2)" "unprognostic (3.46e-1)" "unprognostic (5.88e-2)" "unprognostic (4.59e-3)" KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 87.3" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 128.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.9" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077577 Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 9.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Horizontal cells: 10.7;Inhibitory neurons: 7.6;Late spermatids: 9.2;Oocytes: 51.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 19.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.1;thyroid cancer: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" "Plasma membrane" "HPA075842: " "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.96e-8)" "unprognostic (1.91e-1)" "unprognostic (8.17e-3)" "unprognostic (2.19e-3)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (5.12e-6)" "unprognostic (2.94e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" "unprognostic (1.76e-1)" KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 134.1" "Cell type enhanced" "Detected in many" "Astrocytes: 446.8;Bipolar cells: 485.5;Excitatory neurons: 989.5;Inhibitory neurons: 610.3;Oligodendrocyte precursor cells: 664.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "HPA054648: AB_2682556" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (9.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (5.19e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-3)" KCNMB2 ENSG00000197584 "Potassium calcium-activated channel subfamily M regulatory beta subunit 2" Q9Y691 3 178272932-178844429 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 34.5;fallopian tube: 13.4" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 758.1;Oligodendrocyte precursor cells: 1860.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.9;lymphoma: 7.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB022649 Uncertain NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "CAB022649: " "unprognostic (9.52e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (1.04e-2)" "unprognostic (2.43e-2)" "unprognostic (6.97e-2)" "unprognostic (6.74e-2)" "unprognostic (2.15e-1)" "unprognostic (3.58e-3)" "unprognostic (3.57e-2)" "unprognostic (1.71e-2)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-4)" "unprognostic (7.85e-2)" KCNMB3 "KCNMB2, KCNMBL" ENSG00000171121 "Potassium calcium-activated channel subfamily M regulatory beta subunit 3" Q9NPA1 3 179236691-179267002 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 9.5;Late spermatids: 11.0;Oligodendrocytes: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015665, HPA019185" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm Mitochondria "HPA015665: AB_1852142, HPA019185: AB_1852144" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (6.76e-5)" "unprognostic (2.65e-2)" "unprognostic (2.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.59e-3)" "unprognostic (1.14e-1)" "unprognostic (9.15e-3)" "unprognostic (5.09e-2)" "unprognostic (1.87e-2)" "unprognostic (1.95e-5)" "unprognostic (5.93e-10)" "unprognostic (7.22e-2)" "unprognostic (4.72e-1)" "unprognostic (8.69e-2)" "unprognostic (3.49e-2)" KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 92.2;Inhibitory neurons: 43.2;Oligodendrocytes: 80.8;Schwann cells: 135.6" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.0" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Neurons - Neuronal signaling" 2 Cytosol "HPA072287: AB_2686507" "unprognostic (3.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.69e-2)" "unprognostic (2.62e-2)" "unprognostic (6.98e-2)" "unprognostic (1.13e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-2)" "unprognostic (3.50e-1)" "unprognostic (2.95e-2)" "unprognostic (3.75e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-2)" KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000085 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 106.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 12.4;Langerhans cells: 18.1" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 16.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Dendritic cells - Antigen presentation" "Actin filaments, Cytosol" "HPA065938: AB_2685582" "unprognostic (7.55e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" "unprognostic (7.80e-2)" "unprognostic (1.90e-1)" "unprognostic (8.94e-5)" "unprognostic (3.92e-3)" "unprognostic (1.01e-1)" "unprognostic (8.42e-2)" "unprognostic (3.59e-1)" "unprognostic (2.71e-3)" "unprognostic (3.38e-1)" "unprognostic (5.21e-3)" "unprognostic (2.70e-2)" "unprognostic (1.14e-1)" "unprognostic (7.24e-3)" "unprognostic (3.24e-1)" KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 20.1;liver: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 34.4;Excitatory neurons: 145.1;Inhibitory neurons: 93.0;Oligodendrocyte precursor cells: 59.4;Prostatic glandular cells: 30.0" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 28.6;skin cancer: 8.3" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 65: Neurons - Synaptic function" 1 "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" KCNN3 "hSK3, KCa2.3, SKCA3" ENSG00000143603 "Potassium calcium-activated channel subfamily N member 3" Q9UGI6 1 154697455-154870281 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.3" "Cell type enhanced" "Detected in many" "Astrocytes: 160.1;Ciliated cells: 28.9;Lymphatic endothelial cells: 51.8;Plasma cells: 40.5;Skeletal myocytes: 84.9" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7;memory B-cell: 2.6" "Group enriched" "Detected in many" 12 "B-cells: 2.6;granulocytes: 4.7;monocytes: 1.4" "Group enriched" "Detected in some" 5 "lymphoma: 18.8;Myeloma: 37.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017990, HPA057127" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Plasma membrane, Cytosol" "HPA017990: AB_2669730, HPA057127: AB_2683345" "unprognostic (2.09e-1)" "unprognostic (2.91e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (7.22e-2)" "unprognostic (4.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (9.51e-2)" "unprognostic (4.07e-3)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (6.93e-2)" "unprognostic (1.80e-2)" KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43780976 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 122.7" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 223.3;Syncytiotrophoblasts: 783.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 7 "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 191.0;stomach 1: 96.2" "Cell type enhanced" "Detected in many" "Microglial cells: 68.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 32.2;Gastric cancer: 20.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Endoplasmic reticulum" "Plasma membrane" "HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 136.8" "Group enriched" "Detected in some" 5 "Early spermatids: 19.5;Excitatory neurons: 59.7;Horizontal cells: 30.2;Inhibitory neurons: 35.9;Oligodendrocyte precursor cells: 47.6;Spermatogonia: 31.1" "Cancer enriched" "Detected in some" 9 "glioma: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.5;Neuroblastoma: 51.2" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA016642: AB_1855555, HPA057112: AB_2683339" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-4)" "unprognostic (8.21e-6)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (6.06e-2)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (9.96e-2)" "unprognostic (9.39e-2)" "unprognostic (1.43e-5)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" KCNQ4 "DFNA2, Kv7.4" ENSG00000117013 "Potassium voltage-gated channel subfamily Q member 4" P56696 1 40783787-40840452 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Hearing, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 5.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.9;Inhibitory neurons: 9.3;Muller glia cells: 3.4;Skeletal myocytes: 5.9;Smooth muscle cells: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018305 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA018305: AB_1855556" "unprognostic (1.42e-2)" "unprognostic (1.56e-1)" "unprognostic (8.43e-3)" "unprognostic (4.59e-3)" "unprognostic (8.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (5.86e-2)" "unprognostic (4.34e-2)" "unprognostic (6.64e-2)" "unprognostic (1.20e-1)" "unprognostic (7.40e-2)" "unprognostic (5.18e-4)" "unprognostic (2.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (3.44e-2)" KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 15.7;tongue: 11.3" "Group enriched" "Detected in some" 12 "Excitatory neurons: 2066.7;Inhibitory neurons: 827.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Uncertain "Cytoplasmic bodies" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" "Cytoplasmic bodies" "HPA016655: AB_1855557" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (4.96e-2)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (6.09e-2)" "unprognostic (8.55e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.16e-2)" "unprognostic (1.39e-3)" KCNS2 Kv9.2 ENSG00000156486 "Potassium voltage-gated channel modifier subfamily S member 2" Q9ULS6 8 98426958-98432853 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.9;Excitatory neurons: 4.3;Horizontal cells: 3.1;Inhibitory neurons: 1.6;Leydig cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051417 Uncertain NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA051417: AB_2681478" "unprognostic (7.83e-2)" "unprognostic (9.39e-3)" "unprognostic (5.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (4.27e-2)" "unprognostic (4.58e-2)" "unprognostic (1.47e-1)" "unprognostic (5.30e-5)" "unprognostic (2.43e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-3)" KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 83.0;tongue: 43.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" KCNT1 "KCa4.1, KIAA1422, SLACK, Slo2.2" ENSG00000107147 "Potassium sodium-activated channel subfamily T member 1" Q5JUK3 9 135702185-135795508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 44.5;lymphoid tissue: 15.3;skeletal muscle: 12.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 58.0;Inhibitory neurons: 52.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Neuroblastoma: 5.6" "Heart muscle - Cardiomyocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.2" HPA059880 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "HPA059880: AB_2684149" "unprognostic (1.50e-3)" "unprognostic (1.72e-2)" "unprognostic (2.07e-3)" "unprognostic (2.98e-13)" "unprognostic (9.26e-2)" "unprognostic (7.73e-2)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.30e-3)" "unprognostic (9.89e-2)" "unprognostic (6.20e-2)" "unprognostic (4.89e-7)" "unprognostic (9.15e-2)" "unprognostic (2.70e-1)" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 212.4;Inhibitory neurons: 229.3;Oligodendrocyte precursor cells: 291.5" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.0" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.8" "Group enriched" "Detected in some" 20 "Early spermatids: 68.2;Late spermatids: 25.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "brain: 13.1" "Cell type enriched" "Detected in some" 10 "Excitatory neurons: 27.3" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 48.0" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717510-2730037 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 280.3" "Group enriched" "Detected in some" 10 "Cone photoreceptor cells: 1522.4;Rod photoreceptor cells: 472.1" "Cancer enriched" "Detected in single" 78 "testis cancer: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA031131: AB_10609996" "unprognostic (5.06e-2)" "unprognostic (1.47e-3)" "unprognostic (3.45e-3)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.12e-3)" "unprognostic (5.38e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.35e-1)" "unprognostic (7.96e-8)" "unprognostic (3.01e-1)" "unprognostic (4.90e-2)" "unprognostic (9.90e-2)" "unprognostic (1.06e-2)" KCTD8 ENSG00000183783 "Potassium channel tetramerization domain containing 8" Q6ZWB6 4 44173903-44448809 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 17.6;retina: 6.6" "Group enriched" "Detected in some" 4 "Astrocytes: 160.7;Excitatory neurons: 215.6;Inhibitory neurons: 427.2;Oligodendrocyte precursor cells: 302.8;Oligodendrocytes: 568.6" "Cancer enhanced" "Detected in some" "glioma: 0.9;thyroid cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.2;Neuroblastoma: 1.9" "Adipose visceral - Mesothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031562 Enhanced Approved "Cytoplasmic bodies" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" "Cytoplasmic bodies" "HPA031562: AB_10602609" "unprognostic (1.49e-2)" "unprognostic (7.70e-3)" "unprognostic (1.53e-1)" "unprognostic (4.15e-1)" "unprognostic (1.77e-2)" "unprognostic (1.48e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (2.57e-3)" "unprognostic (8.72e-2)" "unprognostic (3.55e-2)" "unprognostic (2.44e-1)" KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 666.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: AB_10615208" "unprognostic (3.10e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.49e-4)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.35e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.55e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.06e-1)" "unprognostic (1.68e-2)" KDELR2 "ELP-1, ERD2.2" ENSG00000136240 "KDEL endoplasmic reticulum protein retention receptor 2" P33947 7 6445953-6484190 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 899.0;Extravillous trophoblasts: 1067.7;Syncytiotrophoblasts: 818.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016459 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" "HPA016459: AB_1852180" "unprognostic (2.16e-3)" "unprognostic (1.34e-3)" "unprognostic (1.77e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.40e-5)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.85e-2)" "unprognostic (7.05e-2)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (5.42e-1)" "prognostic unfavorable (6.79e-8)" "unprognostic (7.72e-2)" "unprognostic (1.80e-1)" "unprognostic (4.29e-2)" "unprognostic (2.71e-2)" KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 87.8;Fibroblasts: 46.4;Intestinal goblet cells: 60.5;Serous glandular cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA043477: AB_10962952, HPA076405: AB_2686797" "unprognostic (1.76e-1)" "unprognostic (3.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-1)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.05e-10)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (8.24e-2)" "unprognostic (2.07e-2)" KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 138.5;Endothelial cells: 159.5;Lymphatic endothelial cells: 111.0;Mesothelial cells: 193.9;Muller glia cells: 172.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 54.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" Receptor NA NA 11000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 15 Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" 3 "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 55.5;testis: 31.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.4;Erythroid cells: 62.1;Oligodendrocytes: 28.0;Sertoli cells: 21.8;Squamous epithelial cells: 16.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Leukemia: 10.4" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 7 "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" KHDC1 "bA257K9.4, C6orf147, C6orf148, Em:AC019205.8, MGC10818, NDG1" ENSG00000135314 "KH domain containing 1" Q4VXA5 6 73241314-73310365 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 31.8;Inhibitory neurons: 29.5;Oligodendrocyte precursor cells: 27.4;Spermatocytes: 40.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA075996 Approved Vesicles,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Spermatocytes - Spermatogenesis" Cytosol Vesicles "HPA075996: " "unprognostic (3.46e-1)" "unprognostic (2.20e-2)" "unprognostic (1.74e-1)" "unprognostic (2.73e-4)" "unprognostic (1.95e-1)" "unprognostic (2.18e-1)" "unprognostic (1.20e-1)" "unprognostic (7.54e-2)" "unprognostic (5.76e-2)" "unprognostic (6.27e-2)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" "unprognostic (1.83e-4)" "unprognostic (8.18e-2)" "unprognostic (2.97e-1)" "unprognostic (2.14e-1)" "unprognostic (5.17e-3)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;pituitary gland: 4.0" "Group enriched" "Detected in some" 9 "Astrocytes: 113.3;Early spermatids: 52.2;Excitatory neurons: 124.8;Inhibitory neurons: 69.6;Late spermatids: 100.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35393883-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 1100000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" Nucleoli "HPA072692: AB_2686549" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (4.23e-3)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.92e-5)" "unprognostic (3.41e-3)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.79e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (1.84e-1)" KIAA1549 ENSG00000122778 KIAA1549 Q9HCM3 7 138831381-138981389 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 49.8;Excitatory neurons: 89.1;granulocytes: 90.9;Inhibitory neurons: 52.3;Oligodendrocyte precursor cells: 65.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 20.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019560 Uncertain Approved "Nuclear membrane,Intermediate filaments" NA NA 14000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 30: Granulocytes - Unknown function" "Nuclear membrane" "Intermediate filaments" "HPA019560: AB_1852418" "unprognostic (7.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.63e-1)" "unprognostic (6.85e-2)" "unprognostic (2.29e-1)" "unprognostic (8.86e-2)" "unprognostic (2.55e-2)" "unprognostic (6.40e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (2.33e-2)" "unprognostic (8.30e-2)" "prognostic favorable (3.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "unprognostic (2.38e-1)" "unprognostic (1.28e-2)" KIAA1549L "C11orf41, C11orf69, G2, MGC34830" ENSG00000110427 "KIAA1549 like" Q6ZVL6 11 33376108-33674102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 21.5;parathyroid gland: 31.8" "Group enriched" "Detected in some" 7 "Excitatory neurons: 354.6;Inhibitory neurons: 185.3" "Cancer enhanced" "Detected in many" "melanoma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010132, HPA051594" Approved Nucleoplasm,Vesicles NA NA 160000 "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm Vesicles "HPA010132: AB_1078313, HPA051594: " "unprognostic (3.02e-1)" "unprognostic (1.18e-1)" "unprognostic (2.70e-2)" "unprognostic (1.34e-5)" "unprognostic (2.63e-1)" "unprognostic (7.92e-2)" "unprognostic (2.89e-2)" "unprognostic (5.27e-3)" "unprognostic (1.55e-2)" "unprognostic (2.59e-4)" "unprognostic (8.88e-2)" "unprognostic (1.44e-1)" "unprognostic (3.62e-3)" "unprognostic (1.08e-3)" "unprognostic (8.46e-2)" "unprognostic (4.04e-1)" "unprognostic (1.09e-1)" KIAA2013 "MGC33867, RP5-1077B9.1" ENSG00000116685 KIAA2013 Q8IYS2 1 11919591-11926428 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052677, HPA060536" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus" Cytosol "HPA052677: AB_2681911, HPA060536: AB_2684313" "unprognostic (3.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.63e-2)" "unprognostic (1.48e-1)" "unprognostic (2.02e-2)" "unprognostic (1.87e-2)" "unprognostic (5.51e-3)" "unprognostic (8.60e-2)" "unprognostic (5.26e-2)" "unprognostic (2.92e-1)" "unprognostic (1.10e-2)" "unprognostic (5.04e-2)" "unprognostic (6.05e-2)" "unprognostic (2.04e-2)" "unprognostic (2.94e-2)" "unprognostic (8.24e-3)" "unprognostic (3.74e-3)" KIDINS220 ARMS ENSG00000134313 "Kinase D interacting substrate 220" Q9ULH0 2 8721081-8837630 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Neurogenesis "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 299.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014790 Supported Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 28: Neuronal - Transcription" "Cluster 30: White matter - Myelination" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA014790: AB_1852460" "unprognostic (3.58e-1)" "unprognostic (1.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-3)" "unprognostic (2.05e-1)" "unprognostic (2.01e-1)" "unprognostic (1.33e-2)" "prognostic favorable (9.64e-4)" "unprognostic (1.68e-1)" "unprognostic (9.21e-2)" "unprognostic (9.74e-2)" "unprognostic (7.39e-2)" "prognostic favorable (9.29e-6)" "unprognostic (4.12e-2)" "unprognostic (1.47e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-1)" KIRREL1 "KIRREL, NEPH1" ENSG00000183853 "Kirre like nephrin family adhesion molecule 1" Q96J84 1 157993273-158100262 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 17.4;Fibroblasts: 17.8;Granulosa cells: 24.9;Inhibitory neurons: 20.8;Mesothelial cells: 15.8;Smooth muscle cells: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030458 Approved NA NA 890000 "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "HPA030458: AB_10601438" "unprognostic (8.92e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.76e-1)" "unprognostic (1.07e-3)" "unprognostic (7.96e-3)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (2.11e-3)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.85e-4)" KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867136 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 68.0" "Group enriched" "Detected in some" 6 "Bipolar cells: 52.8;Exocrine glandular cells: 13.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" "No annotated function" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Centriolar satellite" "HPA071587: AB_2732182, HPA074326: AB_2732251" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.72e-3)" "unprognostic (3.30e-2)" "unprognostic (5.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.62e-2)" "unprognostic (2.43e-6)" "unprognostic (1.72e-1)" "unprognostic (4.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.62e-2)" KIRREL3 "KIAA1867, KIRRE, NEPH2" ENSG00000149571 "Kirre like nephrin family adhesion molecule 3" Q8IZU9 11 126423358-127003460 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.6" "Group enriched" "Detected in some" 16 "Excitatory neurons: 265.7;Inhibitory neurons: 459.9;Oligodendrocytes: 363.2" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 8.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 8.3" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053324 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 6 "HPA053324: " "unprognostic (1.92e-1)" "unprognostic (5.29e-2)" "unprognostic (1.06e-1)" "unprognostic (4.72e-2)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "unprognostic (4.49e-3)" "unprognostic (6.23e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (7.05e-3)" "unprognostic (3.81e-2)" "unprognostic (4.06e-6)" "unprognostic (9.91e-3)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (2.92e-1)" KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.6;pancreas: 1.3;pituitary gland: 1.1" "Cell type enriched" "Detected in some" 11 "Extravillous trophoblasts: 52.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657267-54740783 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 82.1" "Group enriched" "Detected in many" 6 "granulocytes: 984.7;Melanocytes: 386.5" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 16.1;eosinophil: 9.6;NK-cell: 11.1" "Group enriched" "Detected in many" 7 "granulocytes: 16.1;NK-cells: 11.1" "Cancer enhanced" "Detected in many" "Leukemia: 28.3" "Adipose subcutaneous - Mast cells, Lung - Mast cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 32: Basophils - Transcription" "Cluster 73: Breast - Lactation" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 7 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.9;Basal squamous epithelial cells: 57.0;Collecting duct cells: 73.9;Excitatory neurons: 45.1;Inhibitory neurons: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" "Growth factor" NA NA 260000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 65: Neurons - Synaptic function" 1 Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 18.9;liver: 17.2;pancreas: 5.8" "Cell type enhanced" "Detected in many" "Early spermatids: 10.0;Enteroendocrine cells: 16.6;Hepatocytes: 43.0;Intestinal goblet cells: 17.1;Spermatocytes: 32.9" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 8.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 83: Liver - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.6;lymphoid tissue: 35.4" "Group enriched" "Detected in many" 7 "NK-cells: 1483.6;T-cells: 754.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2180.9" "Group enriched" "Detected in all" 140 "NK-cells: 758.3;T-cells: 2180.9" "Cancer enhanced" "Detected in single" "Brain cancer: 1.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.5" "Group enriched" "Detected in some" 23 "NK-cells: 225.5;T-cells: 104.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 229.7;NK-cell: 368.5" "Group enriched" "Detected in many" 47 "NK-cells: 368.5;T-cells: 229.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 42 "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" KLRC2 "CD159c, NKG2-C, NKG2C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;lymphoid tissue: 5.3" "Group enriched" "Detected in some" 12 "NK-cells: 76.6;Oligodendrocyte precursor cells: 30.7;T-cells: 59.7" "Cancer enriched" "Detected in single" 8 "glioma: 3.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "gdT-cell: 24.7;NK-cell: 84.6" "Group enriched" "Detected in many" 103 "NK-cells: 84.6;T-cells: 24.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.2" "Adipose visceral - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 19: NK-cells - Adaptive immune response" 1 "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (9.05e-4)" "unprognostic (2.54e-2)" "unprognostic (3.77e-2)" "unprognostic (2.51e-3)" "unprognostic (2.83e-1)" "unprognostic (9.49e-4)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (2.88e-1)" "unprognostic (4.00e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-9)" "unprognostic (8.10e-2)" "unprognostic (2.34e-1)" "unprognostic (8.93e-2)" "unprognostic (5.31e-3)" KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 1.8;brain: 4.8;intestine: 1.3;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 5 "NK-cells: 17.1;Oligodendrocyte precursor cells: 34.0;T-cells: 9.7" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.5" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.5" "Cancer enhanced" "Detected in some" "lymphoma: 5.2;thyroid cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6" "Cell type enriched" "Detected in many" 4 "NK-cells: 1385.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 513.3;memory CD8 T-cell: 218.1;naive CD8 T-cell: 219.5;NK-cell: 737.5" "Group enriched" "Detected in many" 66 "NK-cells: 737.5;T-cells: 513.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 19: NK-cells - Adaptive immune response" 2 "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" KLRF1 "CLEC5C, NKp80" ENSG00000150045 "Killer cell lectin like receptor F1" Q9NZS2 12 9827481-9845007 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 17.6" "Cell type enriched" "Detected in some" 10 "NK-cells: 669.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 665.9" "Lineage enriched" "Detected in all" 7 "NK-cells: 665.9" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Low region specificity" "Detected in many" HPA054038 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "HPA054038: " "unprognostic (2.96e-1)" "unprognostic (8.59e-2)" "unprognostic (3.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-4)" "unprognostic (6.06e-2)" "unprognostic (3.68e-2)" "unprognostic (9.95e-3)" "unprognostic (3.00e-1)" "unprognostic (2.90e-1)" "unprognostic (4.43e-2)" "unprognostic (6.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.89e-3)" KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.2" "Group enriched" "Detected in many" 6 "granulocytes: 94.1;NK-cells: 124.8;T-cells: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 391.8;MAIT T-cell: 462.2" "Lineage enriched" "Detected in all" 22 "T-cells: 462.2" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 9 Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" KLRG2 "CLEC15B, FLJ44186" ENSG00000188883 "Killer cell lectin like receptor G2" A4D1S0 7 139452690-139483673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.8;salivary gland: 4.2;thyroid gland: 4.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.9;Basal squamous epithelial cells: 9.5;Collecting duct cells: 5.8;Erythroid cells: 4.2;Squamous epithelial cells: 13.9;Syncytiotrophoblasts: 6.8" "Cancer enriched" "Detected in many" 11 "testis cancer: 42.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.8" "Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018199 Uncertain Uncertain Nucleoplasm NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA018199: AB_2133260" "unprognostic (2.50e-2)" "unprognostic (3.05e-2)" "unprognostic (9.82e-2)" "unprognostic (5.38e-8)" "unprognostic (2.41e-1)" "unprognostic (1.97e-2)" "unprognostic (3.13e-2)" "prognostic favorable (8.61e-4)" "unprognostic (2.14e-2)" "unprognostic (2.92e-1)" "unprognostic (5.19e-2)" "unprognostic (8.83e-2)" "unprognostic (1.10e-3)" "unprognostic (5.66e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-2)" "unprognostic (2.34e-2)" KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.8;lymphoid tissue: 41.8" "Group enriched" "Detected in some" 5 "NK-cells: 26.0;T-cells: 41.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 40 "gdT-cell: 287.0;MAIT T-cell: 111.2;memory CD8 T-cell: 260.3;naive CD8 T-cell: 258.6;NK-cell: 335.6" "Group enriched" "Detected in all" 49 "NK-cells: 335.6;T-cells: 287.0" "Group enriched" "Detected in some" 15 "Leukemia: 9.9;lymphoma: 31.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" 5 "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 30.3;liver: 88.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 46.2;Langerhans cells: 61.9;monocytes: 88.9;Proximal tubular cells: 55.2;Syncytiotrophoblasts: 270.1" "Group enriched" "Detected in many" 4 "breast cancer: 1.6;liver cancer: 3.3;renal cancer: 3.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 100 "classical monocyte: 11.1;intermediate monocyte: 32.3;memory B-cell: 36.2;myeloid DC: 11.3;naive B-cell: 42.2;non-classical monocyte: 34.0;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 122 "B-cells: 42.2;dendritic cells: 24.4;monocytes: 34.0" "Cancer enhanced" "Detected in many" "Bone cancer: 26.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Testis - Early spermatids" "Region enriched" "Detected in single" 4 "thalamus: 1.1" "Low region specificity" "Detected in many" "HPA031115, HPA056942" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA031115: AB_10601924, HPA056942: AB_2683281" "unprognostic (4.27e-2)" "unprognostic (3.35e-2)" "unprognostic (3.95e-2)" "unprognostic (7.48e-3)" "unprognostic (8.37e-3)" "unprognostic (2.63e-1)" "unprognostic (9.79e-2)" "unprognostic (3.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.75e-3)" "unprognostic (8.07e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (6.49e-8)" "unprognostic (1.60e-2)" "unprognostic (3.65e-2)" "unprognostic (3.36e-2)" "unprognostic (6.81e-2)" KMT2E "HDCMC04P, MLL5, SETD5B" ENSG00000005483 "Lysine methyltransferase 2E (inactive)" Q8IZD2 7 104940943-105115019 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Nucleoplasm "Nuclear bodies" "HPA042866: , HPA056125: AB_2683044" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (6.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.94e-1)" "unprognostic (4.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.98e-3)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (3.53e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 56.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.5" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.5" "Cancer enhanced" "Detected in all" "cervical cancer: 55.4" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 75: Serous glandular cells - Salivary secretion" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.9;skin 1: 7.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Basal squamous epithelial cells: 10.6;Cone photoreceptor cells: 10.2;Intestinal goblet cells: 15.9;Rod photoreceptor cells: 12.1;Spermatocytes: 14.8;Spermatogonia: 11.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.8" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" Other NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 153.5;Proximal enterocytes: 170.2;Undifferentiated cells: 179.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.7;memory CD8 T-cell: 2.6;naive B-cell: 6.5;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.5;T-cells: 6.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Nucleoplasm, Cytosol" "HPA047136: AB_2679949, HPA060203: AB_2684221" "prognostic favorable (2.67e-5)" "unprognostic (5.93e-2)" "unprognostic (5.03e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (9.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.04e-1)" "unprognostic (3.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.21e-2)" "unprognostic (9.42e-3)" KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1571.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 30: Non-specific - DNA binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" L1CAM "CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 137.1;intestine: 46.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 72.0;Horizontal cells: 39.7;Melanocytes: 58.4;Schwann cells: 199.6;Sertoli cells: 38.1" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 288.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.3;lymphoid tissue: 23.0;ovary: 18.0" "Cell type enhanced" "Detected in many" "Leydig cells: 38.5;Ovarian stromal cells: 28.1;Peritubular cells: 64.9;T-cells: 53.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "choroid plexus: 8.5" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" Immunity NA NA 13000 "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "CAB002301: AB_564101, HPA013967: AB_1846277" "unprognostic (9.39e-2)" "prognostic favorable (3.89e-4)" "unprognostic (8.88e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (8.85e-2)" "unprognostic (4.63e-3)" "unprognostic (1.94e-2)" "unprognostic (1.97e-3)" "unprognostic (8.71e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (4.62e-11)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" "unprognostic (8.19e-3)" LAIR1 "CD305, LAIR-1" ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.3;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in many" "dendritic cells: 144.7;granulocytes: 80.6;Hofbauer cells: 188.9;Kupffer cells: 90.9;Macrophages: 126.2;monocytes: 115.3;NK-cells: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;Myeloma: 2.3" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" LAMP1 CD107a ENSG00000185896 "Lysosomal associated membrane protein 1" P11279 13 113297239-113323672 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 730.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004260, HPA014750" Supported NA NA 370000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 73: Breast - Lactation" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" 1 "CAB004260: AB_626851, HPA014750: AB_1846219" "unprognostic (3.98e-1)" "unprognostic (1.18e-1)" "unprognostic (7.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.04e-3)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (5.80e-2)" "unprognostic (1.44e-2)" "unprognostic (2.91e-3)" "unprognostic (2.04e-1)" "prognostic favorable (4.15e-5)" "unprognostic (2.06e-2)" "unprognostic (2.22e-1)" "unprognostic (2.59e-1)" "unprognostic (1.54e-1)" LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 472.1;Syncytiotrophoblasts: 485.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 564.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 564.0" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported Vesicles NA NA 520000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "CAB005272: AB_647855, HPA029100: AB_10795022" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (2.66e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (9.73e-2)" "unprognostic (1.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.85e-1)" "unprognostic (6.78e-2)" "unprognostic (2.66e-1)" "unprognostic (5.53e-3)" LAMP3 "CD208, DC-LAMP, DCLAMP, LAMP, TSC403" ENSG00000078081 "Lysosomal associated membrane protein 3" Q9UQV4 3 183122215-183163839 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lung: 212.8" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 454.3" "Cancer enhanced" "Detected in many" "lung cancer: 27.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.6" "Group enriched" "Detected in many" 9 "granulocytes: 5.6;T-cells: 4.8" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Early spermatids" "CAB025133, HPA051467" Enhanced Enhanced Vesicles NA NA 59000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Lung - Lung function" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Alveolar cells - Lung function" Vesicles "CAB025133: , HPA051467: AB_2681495" "unprognostic (1.43e-3)" "unprognostic (2.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.99e-3)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (7.67e-2)" "unprognostic (8.64e-2)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.80e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (1.89e-7)" "unprognostic (3.12e-1)" "unprognostic (4.13e-2)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 249.0" "Cell type enhanced" "Detected in many" "dendritic cells: 194.7;Granulosa cells: 228.3;Horizontal cells: 50.4;Ovarian stromal cells: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.6" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.6" "Group enriched" "Detected in some" 8 "Leukemia: 56.6;Myeloma: 90.7;Neuroblastoma: 37.5" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Ovarian stromal cells - Transcription" Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: AB_10603682, HPA070765: AB_2686309" "unprognostic (2.78e-2)" "unprognostic (3.90e-3)" "unprognostic (5.73e-4)" "unprognostic (5.47e-2)" "unprognostic (7.89e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-3)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (6.46e-6)" "unprognostic (5.12e-3)" "unprognostic (3.74e-2)" "unprognostic (1.08e-2)" "unprognostic (4.49e-3)" LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 3: Basal prostatic cells - Lipid metabolism" 6 "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" LAPTM4B LC27 ENSG00000104341 "Lysosomal protein transmembrane 4 beta" Q86VI4 8 97775057-97853013 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 795.2;Rod photoreceptor cells: 515.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020782, HPA068830" Uncertain Approved "Golgi apparatus" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 19 "Golgi apparatus" "CAB020782: , HPA068830: AB_2686044" "prognostic unfavorable (5.63e-4)" "unprognostic (1.91e-2)" "unprognostic (7.04e-2)" "unprognostic (6.83e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.70e-4)" "prognostic unfavorable (2.70e-6)" "unprognostic (9.25e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-1)" "unprognostic (7.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-1)" "unprognostic (3.14e-1)" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1270.9;lymphoid tissue: 656.2" "Cell type enhanced" "Detected in many" "B-cells: 864.7;granulocytes: 595.7;Hofbauer cells: 1287.1;Kupffer cells: 836.7;Langerhans cells: 561.0;Macrophages: 933.8;monocytes: 2160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 503.4;lymphoma: 523.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 73: B-cells - B-cell function" 10 Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" LARP4B "KIAA0217, LARP5" ENSG00000107929 "La ribonucleoprotein 4B" Q92615 10 806933-931821 "Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036566, HPA042738" Approved Enhanced Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" 16 Cytosol "HPA036566: AB_10673624, HPA042738: AB_2678137" "unprognostic (3.02e-3)" "unprognostic (1.43e-1)" "unprognostic (9.77e-2)" "unprognostic (4.80e-2)" "unprognostic (2.00e-2)" "unprognostic (3.13e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.95e-2)" "unprognostic (2.74e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (8.10e-3)" "unprognostic (1.62e-1)" "unprognostic (6.47e-2)" "unprognostic (2.54e-2)" LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "granulocytes: 20.7;NK-cells: 20.1;T-cells: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "basophil: 308.6;gdT-cell: 303.5;MAIT T-cell: 212.3;memory CD4 T-cell: 295.3;memory CD8 T-cell: 306.9;naive CD4 T-cell: 276.3;naive CD8 T-cell: 267.4;NK-cell: 114.7;T-reg: 411.7" "Group enriched" "Detected in all" 172 "granulocytes: 308.6;NK-cells: 114.7;T-cells: 411.7" "Cancer enhanced" "Detected in all" "Leukemia: 87.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Immunity NA NA 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 6 "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" LAX1 "FLJ20340, LAX" ENSG00000122188 "Lymphocyte transmembrane adaptor 1" Q8IWV1 1 203765177-203776372 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 20.6" "Cell type enhanced" "Detected in some" "granulocytes: 194.1;NK-cells: 30.7;Plasma cells: 58.9;T-cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 14 "B-cells: 7.5;NK-cells: 5.3;T-cells: 12.0" "Cancer enriched" "Detected in some" 6 "Myeloma: 40.5" "Adipose subcutaneous - Mast cells, Breast - Plasma cells, Colon - Mast cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002461, HPA003887, CAB025358" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Granulocytes - Unknown function" 3 "Plasma membrane, Cytosol" "Golgi apparatus" "CAB025358: , HPA002461: AB_1079239, HPA003887: AB_1079240" "unprognostic (2.85e-3)" "unprognostic (3.83e-3)" "unprognostic (3.90e-4)" "unprognostic (3.65e-2)" "unprognostic (5.22e-2)" "unprognostic (1.03e-5)" "unprognostic (2.99e-2)" "unprognostic (4.91e-2)" "unprognostic (4.36e-2)" "unprognostic (3.31e-3)" "unprognostic (4.77e-1)" "unprognostic (4.36e-1)" "unprognostic (4.23e-4)" "unprognostic (3.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.7;Basal respiratory cells: 40.5;Endothelial cells: 44.8;Lymphatic endothelial cells: 168.3;Peritubular cells: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 124 "dendritic cells: 11.2;T-cells: 13.4" "Cancer enhanced" "Detected in many" "Brain cancer: 75.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 216.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049840, HPA062236" Enhanced Enhanced "Nuclear membrane" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Neutrophils - Degranulation" 4 "Nuclear membrane" "HPA049840: AB_2680908, HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LPLAT6, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 65.1;Inhibitory neurons: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 69: Neurons - Neuronal signaling" 3 "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: AB_2680678" "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavorable (9.67e-4)" "prognostic unfavorable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" LCTL "FLJ33279, KLG, KLPH" ENSG00000188501 "Lactase like" Q6UWM7 15 66547179-66565998 "Cancer-related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "brain: 2.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Cone photoreceptor cells: 3.4;Early spermatids: 4.7;Late spermatids: 10.4" "Group enriched" "Detected in some" 5 "glioma: 1.5;melanoma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.6;testis cancer: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA071640 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 13: Spermatids - Transcription" "Plasma membrane" "Endoplasmic reticulum" "HPA071640: AB_2686428" "unprognostic (4.60e-2)" "unprognostic (5.46e-2)" "unprognostic (8.70e-2)" "unprognostic (1.56e-2)" "unprognostic (3.22e-3)" "unprognostic (3.53e-2)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (4.51e-3)" "unprognostic (4.44e-16)" "unprognostic (6.06e-2)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" LDAF1 "promethin, TMEM159" ENSG00000011638 "Lipid droplet assembly factor 1" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 139.6;Squamous epithelial cells: 124.3;Suprabasal keratinocytes: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 7 Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" LDAH "C2orf43, FLJ21820" ENSG00000118961 "Lipid droplet associated hydrolase" Q9H6V9 2 20684014-20823130 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.1;Inhibitory neurons: 55.0;Oligodendrocyte precursor cells: 36.8;Oligodendrocytes: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034729, HPA034730" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 8: Neurons - Neuronal signaling" "HPA034729: AB_10603684, HPA034730: AB_2674304" "unprognostic (1.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.52e-3)" "unprognostic (1.36e-1)" "unprognostic (2.21e-2)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.09e-6)" "unprognostic (3.57e-2)" "unprognostic (1.36e-1)" "unprognostic (1.27e-2)" "unprognostic (6.45e-2)" "unprognostic (2.44e-1)" "prognostic favorable (1.18e-4)" "unprognostic (1.05e-1)" "unprognostic (2.31e-1)" "unprognostic (2.22e-1)" "unprognostic (3.97e-2)" LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 108.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 445.1;Distal enterocytes: 298.1;Suprabasal keratinocytes: 286.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.2" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Endothelial cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA013159" Approved NA NA 23000000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 7 "HPA009647: AB_1079243, HPA013159: AB_1852775" "unprognostic (4.39e-1)" "unprognostic (1.93e-3)" "unprognostic (2.52e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (4.26e-2)" "unprognostic (3.73e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.43e-4)" LDLRAD1 ENSG00000203985 "Low density lipoprotein receptor class A domain containing 1" Q5T700 1 54007298-54018186 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "fallopian tube: 112.4" "Cell type enriched" "Detected in some" 5 "Ciliated cells: 195.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA052489 Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 33 Nucleoplasm "Golgi apparatus" "HPA052489: AB_2681850" "unprognostic (6.53e-3)" "unprognostic (2.05e-2)" "unprognostic (2.51e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.59e-2)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-1)" "unprognostic (8.07e-3)" "unprognostic (2.43e-1)" "unprognostic (2.86e-1)" "unprognostic (5.23e-1)" "unprognostic (4.27e-2)" LDLRAD3 LRAD3 ENSG00000179241 "Low density lipoprotein receptor class A domain containing 3" Q86YD5 11 35943981-36232136 "Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 87.6;Excitatory neurons: 66.5;Microglial cells: 100.2;Oligodendrocyte precursor cells: 289.6;Oligodendrocytes: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.8;non-classical monocyte: 6.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038251 Approved Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Cell Junctions" "HPA038251: AB_10675790" "unprognostic (1.59e-3)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.25e-2)" "unprognostic (4.08e-3)" "unprognostic (1.81e-1)" "unprognostic (1.93e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (9.34e-6)" "unprognostic (2.17e-1)" "unprognostic (1.78e-1)" "unprognostic (1.68e-2)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.05e-8)" "unprognostic (3.32e-2)" "unprognostic (9.21e-3)" "unprognostic (9.33e-2)" "prognostic unfavorable (2.14e-5)" LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.1" "Cell type enhanced" "Detected in many" "dendritic cells: 454.9;Excitatory neurons: 328.0;Inhibitory neurons: 296.4;Late spermatids: 271.8;Microglial cells: 409.7;Oligodendrocyte precursor cells: 299.0;Oligodendrocytes: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 31.0;lymphoma: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "epididymis: 14.5;testis: 53.6" "Cell type enriched" "Detected in many" 6 "Late spermatids: 4290.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 18.4" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" HPA076708 Approved "Plasma membrane" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" 12 "Plasma membrane" "HPA076708: " "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (1.88e-2)" "unprognostic (4.20e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.26e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.31e-1)" "unprognostic (5.66e-6)" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-2)" LEMD2 "dJ482C21.1, LEM2, NET25" ENSG00000161904 "LEM domain nuclear envelope protein 2" Q8NC56 6 33771202-33789130 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017340 Supported Supported "Nuclear membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" "Nuclear membrane" "HPA017340: AB_2296925" "unprognostic (9.01e-2)" "unprognostic (7.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.12e-2)" "unprognostic (2.98e-1)" "unprognostic (8.29e-3)" "unprognostic (6.53e-2)" "unprognostic (5.98e-2)" "unprognostic (4.42e-2)" "unprognostic (7.03e-2)" "unprognostic (1.67e-3)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (2.43e-1)" "unprognostic (7.54e-2)" "unprognostic (3.82e-2)" "unprognostic (7.12e-2)" LEMD3 MAN1 ENSG00000174106 "LEM domain containing 3" Q9Y2U8 12 65169583-65248355 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025078, HPA076986" Uncertain Supported "Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Non-specific - Transcription" 4 "Nuclear membrane" "HPA025078: AB_10601908, HPA076986: AB_2686821" "unprognostic (2.10e-2)" "unprognostic (6.83e-3)" "unprognostic (1.63e-3)" "unprognostic (1.76e-3)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (1.68e-3)" "unprognostic (7.22e-2)" "unprognostic (3.06e-2)" "unprognostic (4.16e-2)" "unprognostic (8.89e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.30e-4)" "unprognostic (4.37e-2)" "unprognostic (3.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" LENG8 "KIAA1932, MGC40108, pp13842" ENSG00000167615 "Leukocyte receptor cluster member 8" Q96PV6 19 54448887-54462016 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 615.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042004, HPA061571" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 35 Nucleoplasm Cytosol "HPA042004: AB_10794642, HPA061571: AB_2684562" "unprognostic (2.09e-2)" "unprognostic (3.24e-3)" "unprognostic (5.14e-3)" "unprognostic (2.19e-1)" "unprognostic (4.42e-2)" "prognostic favorable (7.59e-4)" "unprognostic (1.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.92e-2)" "unprognostic (4.45e-3)" "unprognostic (5.11e-3)" "unprognostic (8.85e-3)" "prognostic unfavorable (3.30e-7)" "unprognostic (3.64e-2)" "unprognostic (6.92e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.73e-6)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 126.5" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 85.6;Fibroblasts: 91.9;Hepatocytes: 137.3;Microglial cells: 123.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" Receptor NA NA 8240000 14000000 "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Fibroblasts - ECM organization" 2 "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" LEPROT "FLJ90360, OB-RGRP, OBRGRP, VPS55" ENSG00000213625 "Leptin receptor overlapping transcript" O15243 1 65420587-65436007 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069444 Approved Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 51: Thyroid gland - Unknown function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" 11 Centrosome "HPA069444: AB_2686137" "unprognostic (3.64e-2)" "unprognostic (2.24e-3)" "unprognostic (1.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "unprognostic (6.13e-3)" "unprognostic (1.52e-1)" "unprognostic (2.21e-1)" "unprognostic (4.88e-2)" "unprognostic (6.85e-2)" "unprognostic (6.43e-3)" "unprognostic (2.25e-2)" "unprognostic (4.56e-3)" "unprognostic (2.25e-3)" "unprognostic (8.22e-2)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" LEPROTL1 "my047, Vps55" ENSG00000104660 "Leptin receptor overlapping transcript like 1" O95214 8 30095408-30177208 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 397.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047911 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 68 "HPA047911: AB_2680206" "unprognostic (4.42e-2)" "unprognostic (1.33e-2)" "prognostic favorable (9.04e-4)" "unprognostic (1.92e-2)" "unprognostic (3.77e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-3)" "unprognostic (5.24e-2)" "unprognostic (2.44e-1)" "unprognostic (4.73e-3)" "unprognostic (2.30e-1)" "unprognostic (9.44e-3)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (2.53e-1)" LETM1 "Mdm38, SLC55A1." ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.1;testis: 23.0" "Cell type enhanced" "Detected in many" "Early spermatids: 96.4;Late spermatids: 53.9;Spermatocytes: 46.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 32.2" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" LETMD1 "HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, SLC55A3" ENSG00000050426 "LETM1 domain containing 1" Q6P1Q0 12 51047962-51060424 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074361 Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 5 Mitochondria "Nucleoplasm, Nucleoli" "HPA074361: AB_2686682" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.11e-1)" "unprognostic (2.20e-2)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "unprognostic (5.05e-2)" "unprognostic (7.86e-2)" "unprognostic (6.57e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.07e-1)" "unprognostic (7.79e-2)" "unprognostic (2.58e-1)" "prognostic favorable (3.16e-4)" LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 193.8;Glandular and luminal cells: 134.5;Syncytiotrophoblasts: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Skin - Outer root sheath cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.3;placenta: 18.4;skeletal muscle: 21.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 51.9;Glandular and luminal cells: 73.9;Oligodendrocyte precursor cells: 42.4;Oligodendrocytes: 97.7;Syncytiotrophoblasts: 25.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 26.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 28.1" "Breast - Fibroblasts" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Golgi apparatus" Nucleoplasm "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.6;Basal squamous epithelial cells: 10.4;Breast myoepithelial cells: 8.2;Cardiomyocytes: 9.3;NK-cells: 10.0;Secretory cells: 11.0;Smooth muscle cells: 6.3;Spermatocytes: 5.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "gdT-cell: 15.5;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.5" "Cancer enhanced" "Detected in many" "Bile duct cancer: 6.9;colorectal cancer: 8.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.1;testis: 2.1" "Cell type enhanced" "Detected in some" "Leydig cells: 1.0;Microglial cells: 6.3;Oligodendrocyte precursor cells: 1.9;Proximal tubular cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009814, HPA073668" Uncertain Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" "Plasma membrane" "Centriolar satellite" "CAB009814: AB_2135467, HPA073668: " "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" LHFPL1 ENSG00000182508 "LHFPL tetraspan subfamily member 1" Q86WI0 X 112630648-112680054 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;salivary gland: 2.8" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Basal prostatic cells: 1.4;Lymphatic endothelial cells: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 3.5" "Low region specificity" "Detected in some" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.5" HPA003029 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 4 "HPA003029: AB_1079248" "unprognostic (2.23e-2)" "unprognostic (2.78e-3)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "unprognostic (2.65e-1)" "unprognostic (1.54e-1)" "unprognostic (5.31e-3)" "unprognostic (1.29e-1)" "unprognostic (4.41e-3)" "unprognostic (5.19e-5)" "unprognostic (1.33e-1)" "unprognostic (7.63e-3)" "unprognostic (4.83e-2)" "unprognostic (1.21e-1)" "unprognostic (6.98e-2)" "unprognostic (1.92e-1)" LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 59.2;Microglial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.0;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 8.0;monocytes: 3.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" 9 "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: AB_10794276, HPA076743: " "unprognostic (2.19e-2)" "unprognostic (3.86e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.44e-3)" "unprognostic (2.32e-1)" "unprognostic (8.43e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.45e-7)" "unprognostic (3.40e-2)" "unprognostic (3.88e-2)" "unprognostic (1.34e-2)" "unprognostic (7.85e-2)" LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328603-104908561 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 14.2;retina: 13.1" "Cell type enriched" "Detected in some" 19 "Oligodendrocyte precursor cells: 4494.9" "Cancer enriched" "Detected in some" 12 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 Vesicles "HPA069691: AB_2686171" "unprognostic (1.20e-2)" "unprognostic (6.91e-2)" "unprognostic (4.59e-3)" "unprognostic (5.03e-2)" "unprognostic (2.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-2)" "unprognostic (5.81e-2)" "unprognostic (5.99e-3)" "unprognostic (8.50e-3)" "unprognostic (3.07e-1)" "unprognostic (1.33e-1)" LHFPL4 GARLH4 ENSG00000156959 "LHFPL tetraspan subfamily member 4" Q7Z7J7 3 9498361-9553822 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.5;pituitary gland: 11.9;retina: 9.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 38.4;Excitatory neurons: 57.9;Horizontal cells: 22.0;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 32.1;Rod photoreceptor cells: 15.9" "Group enriched" "Detected in some" 4 "glioma: 6.8;testis cancer: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gallbladder cancer: 12.9;Neuroblastoma: 13.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041421 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 1 "Golgi apparatus" Nucleoplasm "HPA041421: AB_10796673" "unprognostic (6.81e-2)" "unprognostic (3.65e-2)" "unprognostic (4.50e-1)" "unprognostic (6.62e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (2.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.65e-2)" "unprognostic (6.59e-2)" "unprognostic (1.12e-2)" "unprognostic (3.77e-1)" "unprognostic (1.90e-2)" "unprognostic (6.78e-2)" "unprognostic (2.99e-1)" "unprognostic (3.03e-3)" "unprognostic (8.21e-2)" LHFPL5 "DFNB67, dJ510O8.8, MGC33835, Tmhs" ENSG00000197753 "LHFPL tetraspan subfamily member 5" Q8TAF8 6 35797206-35845397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.0;epididymis: 12.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 10.7;Mucus glandular cells: 15.6;Rod photoreceptor cells: 29.3;Squamous epithelial cells: 14.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029421, HPA055110" Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 108 Vesicles "HPA029421: , HPA055110: AB_2682697" "unprognostic (2.35e-1)" "unprognostic (6.45e-2)" "unprognostic (2.41e-2)" "unprognostic (1.22e-3)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.89e-3)" "unprognostic (2.96e-3)" "unprognostic (2.46e-2)" "unprognostic (1.47e-8)" "unprognostic (5.53e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 178.9;Astrocytes: 205.6;Excitatory neurons: 192.4;Extravillous trophoblasts: 187.2;Fibroblasts: 247.1;Leydig cells: 297.4;Microglial cells: 412.4;Oligodendrocyte precursor cells: 265.5;Smooth muscle cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Uncertain Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" LHFPL7 "bA9F11.1, TMEM211" ENSG00000206069 "LHFPL tetraspan subfamily member 7" Q6ICI0 22 24935098-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.6;salivary gland: 5.6;stomach 1: 3.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.1;Breast myoepithelial cells: 1.6;Club cells: 1.6;Glandular and luminal cells: 1.3;Ionocytes: 8.1;Salivary duct cells: 4.1;Serous glandular cells: 2.4" "Group enriched" "Detected in some" 5 "colorectal cancer: 4.8;endometrial cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 38 "colorectal cancer: 7.5" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA066784: AB_2685722" "unprognostic (7.89e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-2)" "unprognostic (5.97e-3)" "unprognostic (5.88e-2)" "unprognostic (1.31e-3)" "unprognostic (3.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-2)" "unprognostic (8.61e-3)" "unprognostic (3.59e-1)" "unprognostic (4.43e-2)" LILRA4 "CD85g, ILT7" ENSG00000239961 "Leukocyte immunoglobulin like receptor A4" P59901 19 54333185-54339162 "CD markers, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.4;lymphoid tissue: 10.6" "Cell type enriched" "Detected in some" 30 "dendritic cells: 597.3" "Cancer enhanced" "Detected in many" "glioma: 2.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 176.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 176.0" "Not detected" "Not detected" HPA049418 Approved NA NA 12000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 "HPA049418: AB_2680756" "unprognostic (5.11e-2)" "unprognostic (1.21e-4)" "unprognostic (2.65e-2)" "unprognostic (5.94e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-3)" "unprognostic (7.62e-2)" "unprognostic (1.36e-3)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "unprognostic (4.90e-2)" "unprognostic (9.30e-2)" "unprognostic (8.28e-7)" "unprognostic (2.12e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-1)" "unprognostic (5.86e-2)" LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 8.7;lymphoid tissue: 16.5" "Group enriched" "Detected in some" 5 "Hofbauer cells: 19.9;Kupffer cells: 59.9;Macrophages: 28.2;monocytes: 23.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.5;intermediate monocyte: 3.9;neutrophil: 8.4" "Group enriched" "Detected in many" 27 "granulocytes: 8.4;monocytes: 3.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 26.2;lymphoid tissue: 48.7" "Group enriched" "Detected in many" 4 "Hofbauer cells: 87.3;Kupffer cells: 93.5;Macrophages: 79.5;monocytes: 166.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 43.2" "Group enriched" "Detected in many" 4 "granulocytes: 43.2;monocytes: 15.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Skin - Macrophages, Thyroid - Neutrophils" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.7;lung: 13.3;lymphoid tissue: 18.4" "Cell type enhanced" "Detected in some" "dendritic cells: 185.8;Hofbauer cells: 137.3;Kupffer cells: 104.7;Macrophages: 86.8;Plasma cells: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.8" "Group enriched" "Detected in many" 43 "dendritic cells: 37.8;monocytes: 11.0" "Cancer enriched" "Detected in some" 5 "Myeloma: 28.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" HPA052807 Approved NA NA 11000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.3;lymphoid tissue: 47.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 53.7;Kupffer cells: 122.3;Macrophages: 67.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" HPA012069 Approved NA NA 58000000 "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 58: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" LINC02203 ENSG00000280709 "Long intergenic non-protein coding RNA 2203" 15 21552795-21653276 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 5.7" "Group enriched" "Detected in some" 56 "Early spermatids: 216.4;Late spermatids: 106.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Approved Centrosome NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 13: Spermatids - Transcription" Centrosome "HPA057442: AB_2683442" LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 119.8" "Group enriched" "Detected in many" 4 "Astrocytes: 257.0;Excitatory neurons: 262.5;Horizontal cells: 80.6;Inhibitory neurons: 211.2;Microglial cells: 160.1;Oligodendrocyte precursor cells: 225.9;Oligodendrocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 65.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 25000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "Plasma membrane" "HPA074653: AB_2686706" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (3.77e-2)" "unprognostic (3.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (3.23e-7)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" LINGO2 "LERN3, LRRN6C" ENSG00000174482 "Leucine rich repeat and Ig domain containing 2" Q7L985 9 27937617-29213601 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.2;smooth muscle: 8.5" "Group enriched" "Detected in some" 30 "Excitatory neurons: 1535.8;Inhibitory neurons: 940.2" "Cancer enhanced" "Detected in single" "melanoma: 0.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.9" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016633, CAB025361" Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "CAB025361: , HPA016633: AB_1853362" "unprognostic (1.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-4)" "unprognostic (9.86e-4)" "unprognostic (7.55e-3)" "unprognostic (2.67e-6)" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.08e-2)" "unprognostic (2.30e-2)" "unprognostic (1.95e-4)" LINGO3 "LERN2, LRRN6B" ENSG00000220008 "Leucine rich repeat and Ig domain containing 3" P0C6S8 19 2287164-2308154 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.9;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.3;Cone photoreceptor cells: 8.5;Horizontal cells: 6.3;Oligodendrocyte precursor cells: 16.0" "Cancer enhanced" "Detected in some" "glioma: 1.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;eosinophil: 4.0;neutrophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.0" "Cancer enriched" "Detected in some" 5 "Leukemia: 8.1" "Region enhanced" "Detected in all" "basal ganglia: 59.6" "Group enriched" "Detected in many" 8 "basal ganglia: 38.0;cerebellum: 26.2;hippocampal formation: 11.0" "HPA043781, HPA059558" Enhanced Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" Mitochondria "HPA043781: AB_2678668, HPA059558: AB_2684062" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (7.16e-3)" "unprognostic (3.10e-1)" "unprognostic (1.59e-1)" "unprognostic (3.61e-3)" "unprognostic (3.53e-1)" "unprognostic (7.45e-3)" "unprognostic (1.11e-2)" "unprognostic (3.19e-2)" "unprognostic (4.03e-4)" "unprognostic (2.35e-2)" "unprognostic (1.36e-2)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" LINGO4 LRRN6D ENSG00000213171 "Leucine rich repeat and Ig domain containing 4" Q6UY18 1 151800264-151805419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.5;skeletal muscle: 20.6;tongue: 5.3" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.0" "Heart muscle - Cardiomyocytes" "Group enriched" "Detected in many" 4 "cerebellum: 1.8;hypothalamus: 1.0;midbrain: 2.7;pons and medulla: 4.0;thalamus: 1.4" "Region enriched" "Detected in many" 7 "spinal cord: 25.8" HPA060781 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 68: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Vesicles" "HPA060781: AB_2684361" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.33e-3)" "unprognostic (1.96e-1)" "unprognostic (8.65e-2)" "unprognostic (3.16e-2)" "unprognostic (1.49e-5)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (2.39e-1)" "unprognostic (1.94e-4)" "unprognostic (6.92e-2)" "unprognostic (3.94e-4)" "unprognostic (3.84e-1)" "unprognostic (1.65e-1)" "unprognostic (7.06e-2)" "unprognostic (5.60e-2)" LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 852.1;monocytes: 656.9;NK-cells: 644.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2587.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2587.2" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Neutrophils - Degranulation" 47 Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 569.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 77: Plasma cells - Protein processing" 4 Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" LMAN2 "C5orf8, GP36B, VIP36" ENSG00000169223 "Lectin, mannose binding 2" Q12907 5 177315805-177351840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 599.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003927, CAB033812" Approved Supported "Golgi apparatus" NA NA 88000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "CAB033812: AB_2136010, HPA003927: AB_1079257" "unprognostic (5.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.87e-2)" "unprognostic (1.85e-3)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (2.88e-3)" "unprognostic (2.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.51e-3)" "unprognostic (4.56e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (4.43e-2)" "unprognostic (6.13e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-1)" LMAN2L "DKFZp564L2423, VIPL" ENSG00000114988 "Lectin, mannose binding 2 like" Q9H0V9 2 96705929-96740064 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026600 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 2 "HPA026600: AB_1852939" "unprognostic (3.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-2)" "unprognostic (4.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" "unprognostic (6.91e-3)" "unprognostic (1.16e-1)" "unprognostic (5.30e-2)" "unprognostic (8.14e-2)" "unprognostic (2.17e-1)" "unprognostic (1.52e-1)" "unprognostic (3.29e-1)" LMBR1 "ACHP, C7orf2, FLJ11665, ZRS" ENSG00000105983 "Limb development membrane protein 1" Q8WVP7 7 156668946-156893216 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 107.1;Inhibitory neurons: 123.4;Microglial cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016592 Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 8: Neurons - Neuronal signaling" 1 Cytosol "HPA016592: AB_1852943" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (9.49e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-3)" "unprognostic (6.90e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.44e-6)" "unprognostic (3.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.10e-2)" LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 73: B-cells - B-cell function" 1 Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" LMBRD2 DKFZp434H2226 ENSG00000164187 "LMBR1 domain containing 2" Q68DH5 5 36098407-36151887 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 10.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.6" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012165 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA012165: AB_2136131" "unprognostic (9.43e-3)" "unprognostic (3.03e-1)" "unprognostic (1.80e-2)" "unprognostic (7.09e-2)" "unprognostic (1.79e-1)" "unprognostic (9.53e-3)" "unprognostic (6.58e-2)" "unprognostic (8.46e-3)" "unprognostic (6.45e-3)" "unprognostic (2.80e-1)" "unprognostic (8.61e-2)" "unprognostic (6.94e-2)" "unprognostic (2.30e-3)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (5.35e-2)" LMF2 "TMEM112B, TMEM153" ENSG00000100258 "Lipase maturation factor 2" Q9BU23 22 50502949-50507702 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 175.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062626 Approved Approved Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" 3 Centrosome "HPA062626: AB_2684812" "unprognostic (2.69e-1)" "prognostic favorable (3.47e-4)" "unprognostic (8.67e-2)" "unprognostic (2.25e-2)" "unprognostic (1.68e-2)" "unprognostic (5.13e-2)" "unprognostic (1.21e-2)" "unprognostic (2.70e-2)" "unprognostic (5.11e-2)" "unprognostic (2.90e-1)" "unprognostic (2.97e-2)" "unprognostic (3.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.08e-1)" "unprognostic (2.54e-2)" "unprognostic (8.75e-2)" LMLN "Gp63, LMNL1, Msp" ENSG00000185621 "Leishmanolysin like peptidase" Q96KR4 3 197960200-198043720 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 35.4;Early spermatids: 34.0;Late spermatids: 29.4;Spermatocytes: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016481, HPA028844" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Testis - Spermatid development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "Focal adhesion sites" "HPA016481: AB_1852955, HPA028844: AB_10602347" "unprognostic (2.54e-1)" "unprognostic (3.15e-1)" "unprognostic (7.63e-2)" "prognostic favorable (6.77e-4)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (6.36e-2)" "unprognostic (2.98e-1)" "unprognostic (4.82e-3)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 240.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 707.1;Cardiomyocytes: 514.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 35.2;basal ganglia: 57.1;cerebral cortex: 46.1;hippocampal formation: 59.7" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 111.1;Inhibitory neurons: 66.1;Oligodendrocyte precursor cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 34: Neurons - Neuronal signaling" 2 "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.8" "Cell type enhanced" "Detected in many" "Club cells: 30.1;Excitatory neurons: 35.7;Inhibitory neurons: 37.2;Ionocytes: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037513 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" Enzyme NA NA 9800000 "Cluster 32: Basophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 19: NK-cells - Adaptive immune response" 4 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.9;Late spermatids: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Spermatids - Transcription" "Endoplasmic reticulum" Nucleoplasm "HPA014205: AB_2234186" "unprognostic (4.93e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-2)" "unprognostic (8.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (4.17e-3)" "unprognostic (1.63e-1)" "unprognostic (9.27e-2)" "unprognostic (2.35e-3)" "unprognostic (3.43e-2)" LPAR2 "EDG-4, EDG4, LPA2" ENSG00000064547 "Lysophosphatidic acid receptor 2" Q9HBW0 19 19623655-19628930 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019616 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA019616: AB_1847988" "unprognostic (1.60e-2)" "unprognostic (1.83e-3)" "unprognostic (6.39e-2)" "unprognostic (1.19e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-3)" "unprognostic (8.07e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.61e-7)" "prognostic favorable (1.43e-4)" "unprognostic (2.40e-1)" "unprognostic (5.87e-2)" "unprognostic (2.29e-2)" LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 39.1;Ciliated cells: 27.0;Glandular and luminal cells: 50.5;Prostatic glandular cells: 58.8;Secretory cells: 21.1;Sertoli cells: 29.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 21.4" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA013421 Supported "Plasma membrane" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 46 "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78758714 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Fibroblasts: 4.3;Leydig cells: 19.9;Mucus glandular cells: 11.6;Ovarian stromal cells: 4.2" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 7.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 7.8" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;testis cancer: 2.5" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Ovarian stromal cells - Transcription" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3" "Cell type enhanced" "Detected in many" "B-cells: 25.0;Distal enterocytes: 23.3;Hofbauer cells: 34.1;Microglial cells: 32.2;Paneth cells: 23.5;Suprabasal keratinocytes: 20.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 18.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 84.1;T-cells: 66.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Liver - Kupffer cells, Skeletal muscle - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favorable (6.56e-5)" "unprognostic (7.43e-2)" LPAR6 "P2RY5, P2Y5" ENSG00000139679 "Lysophosphatidic acid receptor 6" P43657 13 48389567-48444704 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 284.3;Basal squamous epithelial cells: 246.4;Early spermatids: 265.5;Langerhans cells: 907.0;Late spermatids: 359.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028934 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" 4 "HPA028934: AB_2672833" "unprognostic (1.19e-1)" "unprognostic (4.10e-1)" "unprognostic (8.82e-2)" "unprognostic (9.30e-3)" "unprognostic (2.31e-1)" "unprognostic (5.57e-2)" "unprognostic (7.40e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.07e-2)" "unprognostic (8.00e-2)" "unprognostic (2.63e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "unprognostic (2.09e-2)" "unprognostic (1.94e-2)" LPCAT1 "AGPAT10, AGPAT9, AYTL2, FLJ12443, LPLAT8" ENSG00000153395 "Lysophosphatidylcholine acyltransferase 1" Q8NF37 5 1456480-1523962 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.6;lymphoid tissue: 37.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 510.4;Alveolar cells type 2: 581.2;monocytes: 158.5;Rod photoreceptor cells: 138.2" "Cancer enhanced" "Detected in all" "lung cancer: 79.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012501, HPA022268" Enhanced Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" "Endoplasmic reticulum" "Lipid droplets" "HPA012501: AB_1845224, HPA022268: AB_1845225" "unprognostic (5.33e-3)" "prognostic unfavorable (7.11e-5)" "unprognostic (3.11e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (3.13e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.88e-8)" "unprognostic (5.90e-2)" "unprognostic (6.37e-2)" "unprognostic (2.08e-2)" "prognostic favorable (4.90e-5)" "unprognostic (4.89e-2)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.60e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (4.03e-1)" LPCAT2 "AGPAT11, AYTL1, FLJ20481, LPLAT9, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4;thyroid gland: 83.8" "Cell type enhanced" "Detected in many" "granulocytes: 146.7;Microglial cells: 214.7;monocytes: 126.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 23.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.7;eosinophil: 199.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 7 "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favorable (3.43e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2, LPLAT10" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 96.0;Gastric mucus-secreting cells: 123.2;Paneth cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 2.1" "Cell type enhanced" "Detected in many" "Early spermatids: 22.5;Granulosa cells: 31.5;Schwann cells: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 3 "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 86.2;Inhibitory neurons: 112.8;Microglial cells: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 1 "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 95.7;Oligodendrocytes: 129.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012380, HPA017299" Uncertain Enhanced Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" 1 Cytosol "HPA012380: AB_1853260, HPA017299: AB_2669576" "unprognostic (1.25e-1)" "unprognostic (4.92e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.05e-1)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.29e-1)" "unprognostic (4.13e-1)" "unprognostic (9.85e-2)" "unprognostic (1.64e-1)" "unprognostic (2.06e-2)" "unprognostic (1.79e-3)" "unprognostic (3.29e-2)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" LRCH4 "LRN, LRRN1" ENSG00000077454 "Leucine rich repeats and calponin homology domain containing 4" O75427 7 100574011-100586129 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 15.7;monocytes: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037667, HPA037668" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 14 "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA037667: AB_10671882, HPA037668: AB_10672910" "unprognostic (2.41e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.32e-3)" "unprognostic (2.76e-2)" "unprognostic (3.96e-3)" "unprognostic (8.98e-3)" "unprognostic (3.72e-2)" "unprognostic (2.52e-1)" "unprognostic (5.51e-2)" "unprognostic (2.63e-3)" "unprognostic (7.81e-2)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (7.96e-2)" "unprognostic (1.26e-2)" LRFN2 "FIGLER2, KIAA1246, SALM1" ENSG00000156564 "Leucine rich repeat and fibronectin type III domain containing 2" Q9ULH4 6 40391591-40587364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.3;retina: 3.1" "Cell type enhanced" "Detected in some" "Astrocytes: 22.9;Cone photoreceptor cells: 91.8;Excitatory neurons: 107.8;Inhibitory neurons: 59.9;Oligodendrocyte precursor cells: 46.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.1;Neuroblastoma: 4.2" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076660 Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA076660: AB_2686812" "unprognostic (1.93e-2)" "unprognostic (2.04e-1)" "unprognostic (3.61e-2)" "unprognostic (4.58e-4)" "unprognostic (3.10e-1)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-3)" "unprognostic (4.94e-2)" "unprognostic (1.80e-1)" "unprognostic (9.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (2.66e-4)" LRFN3 "FIGLER1, MGC2656, SALM4" ENSG00000126243 "Leucine rich repeat and fibronectin type III domain containing 3" Q9BTN0 19 35935358-35946624 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048923 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" "HPA048923: AB_2680558" "unprognostic (1.88e-1)" "unprognostic (7.22e-3)" "unprognostic (1.82e-1)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (7.37e-2)" "unprognostic (8.14e-2)" "unprognostic (2.34e-3)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (3.49e-3)" "unprognostic (1.74e-1)" "prognostic favorable (8.46e-7)" "unprognostic (6.84e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-2)" "unprognostic (1.03e-1)" LRFN4 "FIGLER6, MGC3103, SALM3." ENSG00000173621 "Leucine rich repeat and fibronectin type III domain containing 4" Q6PJG9 11 66856647-66860475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 22.0;Late spermatids: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077570 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Non-specific - DNA binding" 8 "HPA077570: " "unprognostic (2.25e-2)" "unprognostic (5.90e-3)" "unprognostic (7.51e-2)" "unprognostic (2.01e-2)" "unprognostic (4.35e-2)" "unprognostic (6.73e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-3)" "unprognostic (6.56e-2)" "unprognostic (6.93e-2)" "unprognostic (5.69e-2)" "unprognostic (9.45e-2)" "unprognostic (1.93e-1)" "unprognostic (6.80e-3)" "unprognostic (1.81e-1)" "unprognostic (2.85e-1)" "unprognostic (3.53e-1)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;cervix: 9.8;parathyroid gland: 10.8" "Group enriched" "Detected in some" 13 "Excitatory neurons: 845.2;Inhibitory neurons: 558.1;Oligodendrocyte precursor cells: 277.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.8;Sarcoma: 3.2" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRIG1 "DKFZP586O1624, LIG-1, LIG1" ENSG00000144749 "Leucine rich repeats and immunoglobulin like domains 1" Q96JA1 3 66378797-66501263 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 139.7" "Cell type enriched" "Detected in many" 5 "Astrocytes: 314.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011846 Approved Approved Cytosol NA NA 78000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Astrocytes - Unknown function" 5 Cytosol "HPA011846: AB_2668545" "unprognostic (6.41e-2)" "unprognostic (4.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.58e-2)" "unprognostic (2.12e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "prognostic favorable (3.01e-5)" "unprognostic (5.12e-1)" "unprognostic (7.86e-2)" "unprognostic (2.62e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (8.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.50e-4)" LRIG2 KIAA0806 ENSG00000198799 "Leucine rich repeats and immunoglobulin like domains 2" O94898 1 113073198-113132260 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015538 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 2100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 2 "Golgi apparatus" Nucleoplasm "HPA015538: AB_2250170" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "unprognostic (9.08e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (4.72e-2)" "unprognostic (1.27e-3)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (3.27e-2)" "unprognostic (5.95e-2)" "unprognostic (1.03e-2)" "unprognostic (1.03e-2)" "unprognostic (1.27e-2)" "unprognostic (2.34e-1)" "unprognostic (8.83e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: Endometrial stromal cells - Transcription" 1 Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" LRIT2 "AC022389.4, LRRC22" ENSG00000204033 "Leucine rich repeat, Ig-like and transmembrane domains 2" A6NDA9 10 84220571-84225544 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "retina: 57.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Cone photoreceptor cells: 5.1;Muller glia cells: 3.2;Rod photoreceptor cells: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA037788 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA037788: AB_10672393" "unprognostic (3.12e-1)" "unprognostic (1.09e-3)" "unprognostic (3.99e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "retina: 17.0" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 20.4;Muller glia cells: 8.1;Rod photoreceptor cells: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Host-virus interaction" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 328.0;Leydig cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.5" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" Receptor NA NA 180000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" LRP10 "DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087" ENSG00000197324 "LDL receptor related protein 10" Q7Z4F1 14 22871740-22881713 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 59.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 59.2" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000932 Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 74: Neutrophils - Degranulation" 21 Nucleoplasm Nucleoli "HPA000932: AB_2281523" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (3.72e-2)" "unprognostic (4.59e-2)" "unprognostic (1.72e-1)" "unprognostic (5.01e-2)" "prognostic unfavorable (3.54e-7)" "prognostic unfavorable (9.17e-4)" "unprognostic (8.32e-2)" "unprognostic (1.48e-2)" "unprognostic (1.97e-2)" "unprognostic (4.55e-2)" "prognostic favorable (6.31e-5)" "unprognostic (3.06e-2)" "unprognostic (8.81e-2)" "unprognostic (2.27e-1)" "unprognostic (4.14e-2)" LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Excitatory neurons: 41.1;Granulosa cells: 26.8;Inhibitory neurons: 42.4;Late spermatids: 48.8;Oligodendrocytes: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 1500000 "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" Vesicles "HPA017267: " "prognostic unfavorable (2.31e-8)" "unprognostic (3.85e-3)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (4.25e-3)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (2.63e-1)" "unprognostic (4.76e-2)" "unprognostic (2.47e-1)" "unprognostic (6.75e-2)" "unprognostic (1.34e-2)" "unprognostic (4.23e-2)" LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.6;Excitatory neurons: 76.1;Inhibitory neurons: 51.3;Oligodendrocyte precursor cells: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.2" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 3 "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.7;thyroid gland: 5.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2010.5;Excitatory neurons: 3622.5;Inhibitory neurons: 2793.9;Oligodendrocyte precursor cells: 5225.5;Oligodendrocytes: 1119.5" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.3" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 33.6;parathyroid gland: 43.3;retina: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 89.3;Cytotrophoblasts: 60.3;Mesothelial cells: 87.8;Oligodendrocytes: 279.4;Proximal tubular cells: 261.6" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 7.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" LRP3 "hLRp105, LRP-3" ENSG00000130881 "LDL receptor related protein 3" O75074 19 33177603-33208864 "Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.3" "Cell type enhanced" "Detected in many" "Astrocytes: 18.0;Bipolar cells: 11.9;Excitatory neurons: 18.8;Horizontal cells: 23.9;Inhibitory neurons: 18.6;Oligodendrocyte precursor cells: 14.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041658 Approved "Lipid droplets" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Lipid droplets" "HPA041658: " "unprognostic (3.10e-1)" "unprognostic (2.55e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (1.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.07e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.12e-7)" "unprognostic (1.34e-1)" "unprognostic (2.71e-3)" "unprognostic (4.36e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.32e-1)" LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.0;skin 1: 30.8" "Group enriched" "Detected in many" 4 "Astrocytes: 116.7;Oligodendrocyte precursor cells: 128.8" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 Mitochondria Nucleoplasm "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312591-68449275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease variant, Osteogenesis imperfecta, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 91.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Enhanced NA NA 1500000 "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "CAB013001: AB_2533267, HPA030505: AB_2673505" "unprognostic (3.67e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.13e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.94e-2)" "unprognostic (9.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.78e-1)" "unprognostic (6.82e-2)" "prognostic favorable (3.55e-10)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.42e-2)" LRP6 ADCAD2 ENSG00000070018 "LDL receptor related protein 6" O75581 12 12116025-12267044 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.7;Oligodendrocyte precursor cells: 101.4;Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 5 "Bile duct cancer: 56.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004490, HPA029925" Enhanced NA NA 390000 "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" 12 "CAB004490: AB_627894, HPA029925: AB_10601768" "unprognostic (1.80e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.37e-2)" "unprognostic (3.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.82e-1)" "unprognostic (5.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-2)" "unprognostic (3.16e-1)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.3;thyroid gland: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 29.1;Bipolar cells: 40.2;Excitatory neurons: 34.7;Horizontal cells: 50.4;Inhibitory neurons: 111.8;Microglial cells: 41.2;Sertoli cells: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" Receptor NA NA 2000000 "Cluster 20: Non-specific - DNA binding" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA073031: AB_2732217" "unprognostic (3.83e-2)" "unprognostic (6.06e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (3.46e-1)" "unprognostic (6.13e-2)" "unprognostic (1.03e-3)" "prognostic unfavorable (7.02e-4)" "unprognostic (6.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (8.88e-16)" "unprognostic (7.73e-3)" "unprognostic (5.47e-2)" "unprognostic (6.98e-2)" "unprognostic (3.00e-2)" LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8;skin 1: 7.0" "Cell type enriched" "Detected in some" 11 "Lymphatic endothelial cells: 41.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.6;Brain cancer: 17.0" "Thyroid - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 13: Skin - Cornification" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" LRRC24 LRRC14OS ENSG00000254402 "Leucine rich repeat containing 24" Q50LG9 8 144522388-144527033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.1;Cone photoreceptor cells: 107.0;Horizontal cells: 37.1;Late spermatids: 69.7;Rod photoreceptor cells: 74.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028171, HPA052250" Enhanced Approved Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" Vesicles "HPA028171: AB_2672504, HPA052250: AB_2681774" "unprognostic (1.75e-1)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "unprognostic (3.63e-2)" LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.5;lymphoid tissue: 59.7" "Group enriched" "Detected in some" 7 "Hofbauer cells: 68.1;Kupffer cells: 100.6;Macrophages: 81.5;monocytes: 208.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.9;eosinophil: 357.0;intermediate monocyte: 512.1;myeloid DC: 229.7;neutrophil: 574.9;non-classical monocyte: 710.4" "Group enriched" "Detected in all" 60 "dendritic cells: 229.7;granulocytes: 574.9;monocytes: 710.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;lymphoma: 2.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 30 "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 281.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 71.0;dendritic cells: 130.2;Intestinal goblet cells: 573.7;Prostatic glandular cells: 93.0;Serous glandular cells: 161.7" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enhanced" "Detected in many" "cerebellum: 6.5" "Immune cell enriched" "Detected in single" 1179 "plasmacytoid DC: 117.8" "Lineage enriched" "Detected in single" 1179 "dendritic cells: 117.8" "Group enriched" "Detected in many" 4 "breast cancer: 19.6;prostate cancer: 35.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" LRRC3 "C21orf102, C21orf30, DKFZP434C128, LRRC3DN" ENSG00000160233 "Leucine rich repeat containing 3" Q9BY71 21 44455510-44462196 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 7.6;Hepatocytes: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017975 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "HPA017975: AB_1853307" "unprognostic (1.36e-2)" "unprognostic (5.48e-3)" "unprognostic (1.49e-2)" "unprognostic (2.10e-4)" "unprognostic (1.55e-1)" "unprognostic (1.74e-2)" "unprognostic (7.20e-3)" "unprognostic (2.59e-1)" "unprognostic (4.61e-1)" "unprognostic (7.43e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-5)" "unprognostic (6.44e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-2)" "unprognostic (6.66e-3)" LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 77.9;Endothelial cells: 147.9;Extravillous trophoblasts: 194.1;Smooth muscle cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in many" 4 "Bone cancer: 4.0;lymphoma: 11.0;Sarcoma: 8.6;testis cancer: 7.0" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" Other NA NA 98000 "Cluster 28: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" LRRC37A KIAA0563 ENSG00000176681 "Leucine rich repeat containing 37A" A6NMS7 17 46292733-46338077 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.8" "Cell type enhanced" "Detected in some" "Astrocytes: 52.6;Excitatory neurons: 84.0;Inhibitory neurons: 79.3;Microglial cells: 47.4;Oligodendrocyte precursor cells: 57.1;Oligodendrocytes: 44.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 51: Oligodendrocytes - Unknown function" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.22e-2)" "unprognostic (3.75e-2)" "unprognostic (6.02e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-2)" "unprognostic (5.23e-2)" "unprognostic (5.20e-2)" "unprognostic (8.22e-2)" "unprognostic (2.05e-1)" "unprognostic (2.65e-3)" "unprognostic (3.37e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-2)" "unprognostic (4.30e-2)" LRRC37A2 FLJ45049 ENSG00000238083 "Leucine rich repeat containing 37 member A2" A6NM11 17 46511508-46556910 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.7" "Cell type enhanced" "Detected in many" "Astrocytes: 32.2;Early spermatids: 49.6;Excitatory neurons: 54.0;Inhibitory neurons: 53.2;Microglial cells: 33.1;Oligodendrocyte precursor cells: 44.8;Oligodendrocytes: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "unprognostic (8.96e-2)" "unprognostic (6.35e-2)" "unprognostic (2.53e-1)" "unprognostic (2.97e-3)" "unprognostic (4.61e-3)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (8.00e-2)" "unprognostic (3.02e-7)" "unprognostic (8.40e-2)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" LRRC37A3 "FLJ34306, KIAA0563" ENSG00000176809 "Leucine rich repeat containing 37 member A3" O60309 17 64854130-64919480 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 28.1" "Cell type enhanced" "Detected in many" "Astrocytes: 78.3;Excitatory neurons: 138.3;Inhibitory neurons: 154.5;Microglial cells: 72.5;Oligodendrocyte precursor cells: 103.3;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "HPA042121, HPA043056, HPA045090" Supported Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211" "unprognostic (2.28e-1)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (2.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.84e-2)" "unprognostic (2.27e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-2)" "unprognostic (5.31e-6)" "unprognostic (1.83e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (2.26e-1)" "unprognostic (4.89e-2)" "unprognostic (5.18e-2)" "unprognostic (7.43e-3)" LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007383-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 37.2;Early spermatids: 74.1;Excitatory neurons: 43.8;Inhibitory neurons: 32.0;Oligodendrocyte precursor cells: 37.3;Oligodendrocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.0;NK-cells: 5.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" HPA015135 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 18: Early spermatids - Unknown function" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" LRRC38 ENSG00000162494 "Leucine rich repeat containing 38" Q5VT99 1 13474973-13514003 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.0;skeletal muscle: 43.0;tongue: 14.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.8;Inhibitory neurons: 10.3;Oocytes: 48.5;Skeletal myocytes: 20.5" "Group enriched" "Detected in some" 4 "head and neck cancer: 0.5;lung cancer: 0.8;testis cancer: 0.6;urothelial cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038778 Approved NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" "HPA038778: AB_10673294" "unprognostic (5.13e-2)" "unprognostic (3.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.88e-1)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (1.72e-1)" "unprognostic (2.70e-1)" "unprognostic (9.70e-2)" "unprognostic (4.23e-1)" "unprognostic (7.81e-2)" "unprognostic (4.47e-2)" "unprognostic (1.05e-1)" LRRC3B LRP15 ENSG00000179796 "Leucine rich repeat containing 3B" Q96PB8 3 26622772-26717537 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.5;skeletal muscle: 9.1;testis: 7.0" "Group enriched" "Detected in some" 4 "Astrocytes: 243.7;Early spermatids: 172.3" "Group enriched" "Detected in some" 9 "endometrial cancer: 0.7;glioma: 2.6;ovarian cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 2.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015568 Approved NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 6 "HPA015568: AB_1853282" "unprognostic (1.22e-2)" "unprognostic (2.94e-1)" "unprognostic (1.87e-1)" "unprognostic (7.42e-2)" "unprognostic (8.82e-4)" "unprognostic (2.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.77e-1)" "unprognostic (1.91e-4)" "unprognostic (3.31e-2)" "unprognostic (2.63e-1)" "unprognostic (1.60e-1)" "unprognostic (2.82e-1)" LRRC3C ENSG00000204913 "Leucine rich repeat containing 3C" A6NJW4 17 39927732-39944999 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 1.1;testis: 1.0" "Group enriched" "Detected in some" 4 "Astrocytes: 10.8;Microglial cells: 3.6;Oligodendrocytes: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071271 Uncertain NA NA "Cluster 63: Testis - Spermatid development" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" "HPA071271: AB_2686378" "unprognostic (1.59e-1)" "unprognostic (6.57e-2)" "unprognostic (6.17e-2)" "unprognostic (2.81e-1)" "unprognostic (3.16e-4)" "unprognostic (9.20e-2)" "unprognostic (4.27e-1)" "unprognostic (6.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.14e-1)" "unprognostic (1.90e-2)" LRRC4 NAG14 ENSG00000128594 "Leucine rich repeat containing 4" Q9HBW1 7 128027071-128032107 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 33.6;Horizontal cells: 33.4;Inhibitory neurons: 21.7;Rod photoreceptor cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 13.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.2" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051100 Approved "Golgi apparatus" NA NA 2100000 "Cluster 4: Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Golgi apparatus" "HPA051100: AB_2797241" "unprognostic (7.98e-2)" "unprognostic (6.15e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.34e-3)" "unprognostic (3.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (3.23e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.98e-4)" "unprognostic (4.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (5.84e-3)" LRRC4B "DKFZp761A179, HSM, LRIG4" ENSG00000131409 "Leucine rich repeat containing 4B" Q9NT99 19 50516892-50568435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.0;cervix: 40.0;pituitary gland: 31.1" "Cell type enhanced" "Detected in some" "Astrocytes: 33.1;Bipolar cells: 15.9;Excitatory neurons: 31.0;Horizontal cells: 27.1;Inhibitory neurons: 36.8;Oligodendrocyte precursor cells: 27.8;Oligodendrocytes: 45.5" "Group enriched" "Detected in many" 9 "glioma: 36.5;testis cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 14.6;Neuroblastoma: 25.7;Rhabdoid: 21.3;skin cancer: 6.7" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058986 Uncertain NA NA 2700000 "Cluster 33: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA058986: AB_2683871" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-2)" "unprognostic (4.48e-2)" "unprognostic (3.56e-1)" "unprognostic (5.39e-4)" "unprognostic (2.70e-2)" "unprognostic (1.11e-1)" "unprognostic (5.28e-2)" "unprognostic (4.61e-3)" "unprognostic (1.11e-3)" "unprognostic (3.41e-1)" "unprognostic (3.15e-5)" "unprognostic (4.29e-2)" "unprognostic (2.61e-1)" "unprognostic (3.64e-1)" "unprognostic (2.17e-1)" LRRC4C "KIAA1580, NGL-1" ENSG00000148948 "Leucine rich repeat containing 4C" Q9HCJ2 11 40114203-41459773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 20.1;retina: 16.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 5158.5" "Cancer enhanced" "Detected in some" "glioma: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 7.9" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054800, HPA075816" Supported Approved Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 18 Cytosol "HPA054800: AB_2682603, HPA075816: " "unprognostic (4.86e-3)" "unprognostic (3.43e-2)" "unprognostic (7.62e-3)" "unprognostic (4.87e-3)" "unprognostic (6.48e-2)" "unprognostic (1.42e-1)" "unprognostic (2.84e-1)" "unprognostic (4.64e-2)" "unprognostic (1.93e-1)" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (4.90e-13)" "unprognostic (5.05e-4)" "unprognostic (5.21e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-3)" LRRC53 ENSG00000162621 "Leucine rich repeat containing 53" A6NM62 1 74469376-74512611 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 7.3;Excitatory neurons: 2.1;Horizontal cells: 1.3;Inhibitory neurons: 1.6;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" HPA054062 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA054062: AB_2682364" "unprognostic (3.67e-1)" LRRC55 FLJ45686 ENSG00000183908 "Leucine rich repeat containing 55" Q6ZSA7 11 57181747-57191717 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;lymphoid tissue: 2.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 1.1;Excitatory neurons: 1.8;Inhibitory neurons: 1.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in some" 9 "glioma: 9.0;ovarian cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 3.1" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in all" "olfactory bulb: 105.4" "Low region specificity" "Detected in all" HPA014053 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA014053: AB_2137630" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (3.68e-2)" "unprognostic (3.03e-2)" "unprognostic (2.78e-3)" "unprognostic (2.29e-3)" "unprognostic (2.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (9.43e-2)" "unprognostic (2.11e-2)" "unprognostic (3.32e-2)" "unprognostic (7.17e-4)" "unprognostic (6.66e-2)" "unprognostic (3.59e-1)" "unprognostic (3.79e-2)" LRRC59 "FLJ21675, PRO1855" ENSG00000108829 "Leucine rich repeat containing 59" Q96AG4 17 50375059-50397523 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 299.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030827, HPA030829" Enhanced Enhanced "Endoplasmic reticulum" NA NA 740000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Plasma cells - Protein processing" 14 "Endoplasmic reticulum" "HPA030827: AB_10602704, HPA030829: AB_10670045" "unprognostic (4.73e-2)" "unprognostic (2.15e-2)" "prognostic favorable (2.60e-4)" "unprognostic (5.63e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (1.00e-5)" "prognostic unfavorable (3.12e-6)" "unprognostic (1.88e-3)" "unprognostic (9.95e-2)" "unprognostic (5.62e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (3.68e-2)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.77e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-3)" "prognostic unfavorable (1.90e-5)" LRRC66 ENSG00000188993 "Leucine rich repeat containing 66" Q68CR7 4 51993652-52020363 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.4;skeletal muscle: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 5.6;Distal enterocytes: 9.2;Excitatory neurons: 9.1;Inhibitory neurons: 7.1;Oligodendrocyte precursor cells: 7.5;Oligodendrocytes: 8.1;Paneth cells: 5.3;Proximal enterocytes: 19.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014549, HPA027839" Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA014549: AB_1853062, HPA027839: AB_10602705" "unprognostic (1.10e-1)" "unprognostic (4.87e-2)" "unprognostic (8.62e-2)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (2.57e-2)" "unprognostic (4.83e-3)" "unprognostic (2.93e-1)" "unprognostic (4.09e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (6.31e-3)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.05e-1)" "unprognostic (4.06e-1)" LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Endothelial cells: 2.6;granulocytes: 3.6;Lymphatic endothelial cells: 11.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" LRRC8B "KIAA0231, TA-LRRP" ENSG00000197147 "Leucine rich repeat containing 8 VRAC subunit B" Q6P9F7 1 89524829-89597861 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 85.4;Excitatory neurons: 171.6;Inhibitory neurons: 188.9;Late spermatids: 85.3;Oligodendrocytes: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017950 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 65: Neurons - Synaptic function" 1 "HPA017950: AB_1853346" "unprognostic (2.50e-2)" "unprognostic (3.93e-2)" "prognostic favorable (7.15e-4)" "prognostic unfavorable (9.99e-4)" "unprognostic (1.22e-1)" "unprognostic (5.24e-2)" "unprognostic (3.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-1)" "unprognostic (8.80e-3)" "unprognostic (2.30e-2)" "unprognostic (1.85e-1)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 72.3;Excitatory neurons: 71.1;Inhibitory neurons: 95.1;Microglial cells: 177.1;Oligodendrocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 9.0;monocytes: 6.6;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Uncertain "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" LRRC8E FLJ23420 ENSG00000171017 "Leucine rich repeat containing 8 VRAC subunit E" Q6NSJ5 19 7888505-7902021 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 12.2;Basal squamous epithelial cells: 9.3;Glandular and luminal cells: 12.5;Squamous epithelial cells: 11.6;Suprabasal keratinocytes: 15.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020466 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "HPA020466: AB_1853352" "unprognostic (3.79e-2)" "unprognostic (2.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-3)" "unprognostic (8.28e-3)" "unprognostic (7.64e-2)" "unprognostic (1.71e-2)" "unprognostic (3.36e-1)" "unprognostic (8.38e-2)" "unprognostic (3.98e-6)" "unprognostic (1.11e-1)" "unprognostic (2.30e-2)" "unprognostic (3.29e-2)" "unprognostic (3.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-1)" LRRN1 FIGLER3 ENSG00000175928 "Leucine rich repeat neuronal 1" Q6UXK5 3 3799431-3849834 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 392.4" "Cancer enhanced" "Detected in many" "glioma: 20.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "testis cancer: 96.2" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011071 Enhanced NA NA 2400000 "Cluster 33: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "HPA011071: AB_1853355" "unprognostic (1.27e-2)" "unprognostic (4.87e-1)" "unprognostic (1.32e-2)" "unprognostic (3.30e-3)" "unprognostic (2.01e-2)" "unprognostic (3.02e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.34e-1)" "unprognostic (2.96e-1)" "unprognostic (2.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-3)" "unprognostic (1.86e-3)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (7.25e-2)" LRRN2 "FIGLER7, GAC1, LRANK1, LRRN5" ENSG00000170382 "Leucine rich repeat neuronal 2" O75325 1 204617170-204685738 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 21.1;Excitatory neurons: 55.9;Granulosa cells: 15.8;Horizontal cells: 20.8;Inhibitory neurons: 38.2;Oligodendrocyte precursor cells: 36.8" "Group enriched" "Detected in many" 6 "breast cancer: 6.1;endometrial cancer: 10.6;glioma: 16.8;ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.4;testis cancer: 9.0" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029124 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA029124: AB_10601545" "unprognostic (2.16e-2)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.59e-7)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (2.89e-2)" "unprognostic (1.21e-1)" "unprognostic (4.63e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "unprognostic (1.16e-2)" "unprognostic (1.68e-2)" "unprognostic (1.43e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-1)" "unprognostic (1.59e-3)" LRRN3 "FIGLER5, FLJ11129, NLRR3" ENSG00000173114 "Leucine rich repeat neuronal 3" Q9H3W5 7 111091006-111125454 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 22.5;thyroid gland: 19.0" "Cell type enhanced" "Detected in many" "Astrocytes: 44.6;Cardiomyocytes: 30.6;Excitatory neurons: 78.4;Horizontal cells: 38.4;Inhibitory neurons: 44.4;Leydig cells: 57.4;Oligodendrocyte precursor cells: 57.5" "Group enriched" "Detected in many" 7 "glioma: 17.5;thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 32.6;naive CD8 T-cell: 31.0" "Lineage enriched" "Detected in single" 70 "T-cells: 32.6" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 56.6" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043820, HPA046792" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA043820: AB_2678687, HPA046792: AB_2679810" "unprognostic (4.93e-2)" "unprognostic (4.55e-2)" "unprognostic (5.92e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-2)" "unprognostic (4.78e-3)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.84e-2)" "unprognostic (4.85e-3)" "unprognostic (1.08e-2)" "unprognostic (3.29e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (7.23e-2)" LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 8.0;lung: 10.1" "Group enriched" "Detected in some" 11 "Alveolar cells type 1: 26.4;Mesothelial cells: 51.4" "Group enriched" "Detected in many" 7 "lung cancer: 4.6;ovarian cancer: 3.6;renal cancer: 11.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.3" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 73000 "Cluster 57: Lung - Lung function" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: AB_2686770" "unprognostic (6.16e-2)" "unprognostic (1.69e-3)" "unprognostic (2.40e-3)" "unprognostic (9.04e-3)" "unprognostic (5.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (8.94e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-3)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "unprognostic (2.31e-1)" "unprognostic (9.84e-3)" LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 54.2;Leydig cells: 27.0;Lymphatic endothelial cells: 38.2;Melanocytes: 25.8;Ovarian stromal cells: 21.3;Peritubular cells: 17.1" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.8" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" LRRTM1 FLJ32082 ENSG00000162951 "Leucine rich repeat transmembrane neuronal 1" Q86UE6 2 80288351-80304752 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.4;salivary gland: 12.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Horizontal cells: 5.0;Inhibitory neurons: 12.5;Oligodendrocyte precursor cells: 9.9;Schwann cells: 33.5" "Group enriched" "Detected in many" 11 "endometrial cancer: 8.8;ovarian cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 8.0;Rhabdoid: 7.3" "Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046607, HPA062660" Approved Approved "Golgi apparatus" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Golgi apparatus" "HPA046607: , HPA062660: AB_2684824" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (5.63e-2)" "unprognostic (6.67e-2)" "unprognostic (4.35e-1)" "unprognostic (2.66e-1)" "unprognostic (8.16e-2)" "unprognostic (6.03e-3)" "unprognostic (7.10e-4)" "unprognostic (3.16e-2)" "unprognostic (1.90e-1)" "unprognostic (4.96e-4)" LRTM2 ENSG00000166159 "Leucine rich repeats and transmembrane domains 2" Q8N967 12 1820267-1836753 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 9.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.9;Excitatory neurons: 9.8;Horizontal cells: 21.4;Inhibitory neurons: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 4.3" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055094, HPA062745" Uncertain Approved Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Cytosol "HPA055094: AB_2682693, HPA062745: " "unprognostic (1.84e-3)" "unprognostic (4.83e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (5.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-3)" "unprognostic (2.25e-1)" "unprognostic (1.24e-1)" "unprognostic (6.20e-4)" "unprognostic (2.21e-1)" "unprognostic (8.02e-2)" LRTOMT "CFAP111, COMT2, DFNB63, LRRC51, LRTOMT1, LRTOMT2" ENSG00000284922 "Leucine rich transmembrane and O-methyltransferase domain containing" Q8WZ04 11 72080331-72110782 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 4.9;testis: 8.8" "Group enriched" "Detected in some" 7 "Early spermatids: 16.9;Late spermatids: 33.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039949 Approved Uncertain Microtubules NA NA "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" Microtubules "HPA039949: AB_10960708" LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8;retina: 39.4" "Group enriched" "Detected in many" 14 "Astrocytes: 3206.6;Excitatory neurons: 967.0;Inhibitory neurons: 2049.7;Oligodendrocyte precursor cells: 2327.6;Oligodendrocytes: 869.2" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 12 Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" LSMEM1 "C7orf53, FLJ39575" ENSG00000181016 "Leucine rich single-pass membrane protein 1" Q8N8F7 7 112480853-112491062 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 78.7" "Cell type enhanced" "Detected in many" "Early spermatids: 9.5;Excitatory neurons: 8.2;Inhibitory neurons: 7.3;Late spermatids: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "amygdala: 1.4;basal ganglia: 1.0;cerebellum: 4.0;olfactory bulb: 3.3" "Low region specificity" "Detected in all" "HPA013753, HPA047988" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" 5 Cytosol Vesicles "HPA013753: AB_1848926, HPA047988: AB_2680229" "unprognostic (6.87e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-2)" "unprognostic (2.77e-2)" "unprognostic (1.38e-1)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (6.68e-2)" "unprognostic (3.54e-2)" "unprognostic (2.80e-3)" "unprognostic (1.47e-6)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.25e-2)" "unprognostic (3.42e-2)" LSMEM2 "C3orf45, FLJ38608" ENSG00000179564 "Leucine rich single-pass membrane protein 2" Q8N112 3 50279087-50288114 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.0;skeletal muscle: 15.5" "Cell type enriched" "Detected in some" 14 "Late spermatids: 279.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079523 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Late spermatids - Unknown function" 18 "Plasma membrane" Nucleoplasm "HPA079523: " "unprognostic (2.84e-3)" "unprognostic (6.54e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.46e-2)" "unprognostic (2.48e-1)" "unprognostic (6.49e-3)" "unprognostic (1.71e-1)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 209.3;Distal enterocytes: 256.9;Ductal cells: 236.0;Exocrine glandular cells: 243.4;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cell Junctions" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 98.8;lymphoid tissue: 177.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 856.7;Kupffer cells: 1125.1;Langerhans cells: 1596.9;Macrophages: 732.6;monocytes: 3867.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1767.7" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 17 "Leukemia: 45.7" "Adipose visceral - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 106.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.8;Kupffer cells: 44.5;Suprabasal keratinocytes: 94.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 100.8" "Group enriched" "Detected in many" 6 "granulocytes: 100.8;monocytes: 38.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" HPA003873 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA003873: AB_1078288" "unprognostic (4.07e-2)" "unprognostic (7.67e-2)" "unprognostic (3.67e-3)" "unprognostic (2.40e-3)" "unprognostic (4.90e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "prognostic favorable (1.85e-4)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (2.88e-1)" "unprognostic (2.97e-1)" "unprognostic (6.59e-2)" "unprognostic (7.45e-2)" LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.6;skin 1: 44.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.6;Basal squamous epithelial cells: 15.7;Squamous epithelial cells: 16.0;Suprabasal keratinocytes: 25.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.4;intermediate monocyte: 66.4;myeloid DC: 49.9;neutrophil: 45.2;non-classical monocyte: 50.3" "Group enriched" "Detected in many" 36 "dendritic cells: 49.9;granulocytes: 45.2;monocytes: 71.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 5 "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "granulocytes: 626.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 20.4;eosinophil: 63.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.3" "Cancer enriched" "Detected in single" 11 "Leukemia: 5.6" "Low region specificity" "Detected in all" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 8 Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.8;lung: 14.6;salivary gland: 11.4" "Group enriched" "Detected in some" 4 "dendritic cells: 25.2;Distal enterocytes: 28.1;Gastric mucus-secreting cells: 15.9;Intestinal goblet cells: 9.5;Proximal enterocytes: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Low cancer specificity" "Detected in many" "Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 124.5;Late spermatids: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 21: Early spermatids - Spermatogenesis" 3 Cytosol "CAB034164: AB_2180094, HPA029143: AB_10671360, HPA055604: AB_2682859" "unprognostic (3.67e-2)" "unprognostic (7.07e-2)" "unprognostic (7.78e-2)" "unprognostic (3.99e-1)" "unprognostic (1.42e-2)" "unprognostic (3.66e-3)" "unprognostic (5.38e-2)" "unprognostic (5.40e-2)" "unprognostic (9.98e-2)" "unprognostic (4.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (9.87e-2)" "unprognostic (1.72e-1)" "unprognostic (8.22e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2016.2;skin 1: 824.2;vagina: 476.6" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 2217.7;Squamous epithelial cells: 2055.8;Suprabasal keratinocytes: 5217.5" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 204.9;Esophageal cancer: 170.2;head and neck cancer: 319.3" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" LY6G5C "C6orf20, G5c, NG33" ENSG00000204428 "Lymphocyte antigen 6 family member G5C" Q5SRR4 6 31676684-31684040 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enhanced" "Detected in many" "Early spermatids: 28.8;Spermatocytes: 16.9;Spermatogonia: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038690 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 50: Lymphoma - Unknown function" "Cluster 57: Platelets - Hemostasis" "HPA038690: AB_10673286" "unprognostic (1.51e-2)" "unprognostic (7.26e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.07e-4)" "unprognostic (4.83e-1)" "unprognostic (6.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-2)" "unprognostic (5.63e-2)" "unprognostic (3.74e-5)" "unprognostic (5.84e-2)" "unprognostic (3.78e-4)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.88e-2)" "unprognostic (1.39e-2)" LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715348-31717919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "seminal vesicle: 6.5;skin 1: 23.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "colorectal cancer: 46.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 6.1" "Not detected" "Not detected" HPA054412 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" LY6G6F "C6orf21, G6f, LY6G6D, NG32" ENSG00000204424 "Lymphocyte antigen 6 family member G6F" Q5SQ64 6 31706866-31710679 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;lymphoid tissue: 1.2;skin 1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.7;Leukemia: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008053 Uncertain NA NA 380000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 2 "HPA008053: AB_1840160" "unprognostic (3.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.66e-3)" LY6G6F-LY6G6D "G6F-LY6G6D, MEGT-1, MEGT1" ENSG00000250641 "LY6G6F-LY6G6D readthrough" 6 31706904-31717918 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "skin 1: 5.2;testis: 2.8" "Cell type enriched" "Detected in some" 5 "Enteroendocrine cells: 18.0" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008053 Uncertain NA NA "Cluster 13: Skin - Cornification" "Cluster 47: Leukemia - Hemostasis" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA008053: AB_1840160" "unprognostic (5.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.47e-1)" "unprognostic (5.90e-2)" "unprognostic (1.07e-2)" "unprognostic (2.66e-1)" "unprognostic (2.42e-1)" LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.1;testis: 35.0" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 231.7;Spermatocytes: 444.7" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.7" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.7" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 742.9" "Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 21: Testis - Unknown function" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 76.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 20.7;Distal enterocytes: 19.7;Proximal enterocytes: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 19.6;Myeloma: 18.0" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 24: Non-specific - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" LY75-CD302 ENSG00000248672 "LY75-CD302 readthrough" 2 159771851-159904710 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;intestine: 1.7;lymphoid tissue: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 4.2" HPA049108 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Small intestine - Absorption" "Cluster 43: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA049108: AB_2680635" "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (2.33e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (1.68e-4)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (3.32e-1)" "unprognostic (4.47e-2)" "unprognostic (1.88e-1)" LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.3;intestine: 11.7;lymphoid tissue: 30.3" "Cell type enhanced" "Detected in some" "B-cells: 242.6;dendritic cells: 61.9;Langerhans cells: 37.4;Plasma cells: 84.4;T-cells: 44.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 113.2;MAIT T-cell: 113.7;memory B-cell: 56.2;memory CD4 T-cell: 97.8;memory CD8 T-cell: 109.8;naive B-cell: 53.0;naive CD4 T-cell: 110.0;naive CD8 T-cell: 112.6;plasmacytoid DC: 73.0;T-reg: 80.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 15.9;Myeloma: 38.0" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Pancreas - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 11: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: B-cells - B-cell function" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1036.9;skin 1: 648.7;vagina: 472.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 566.7;Squamous epithelial cells: 881.0;Suprabasal keratinocytes: 2620.9;Syncytiotrophoblasts: 1053.6" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cancer enhanced" "Detected in many" "cervical cancer: 111.3" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 49.0" "Group enriched" "Detected in many" 4 "Early spermatids: 43.2;Late spermatids: 97.5;Syncytiotrophoblasts: 25.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 10.5" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 8 "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" LYPLA1 "APT-1, LPL1" ENSG00000120992 "Lysophospholipase 1" O75608 8 54046367-54102017 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 613.5;Late spermatids: 882.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050941, HPA063151" Enhanced Approved Nucleoplasm,Cytosol NA NA 330000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" 2 "Nucleoplasm, Cytosol" "HPA050941: AB_2681284, HPA063151: " "unprognostic (2.62e-2)" "unprognostic (1.28e-2)" "unprognostic (3.25e-3)" "unprognostic (9.42e-2)" "unprognostic (9.48e-2)" "unprognostic (3.56e-1)" "unprognostic (9.58e-2)" "unprognostic (2.05e-2)" "unprognostic (6.52e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.58e-1)" "unprognostic (2.15e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (2.56e-3)" LYSMD3 FLJ13542 ENSG00000176018 "LysM domain containing 3" Q7Z3D4 5 90515611-90529584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018024 Approved Approved Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Cytosol "HPA018024: AB_2138525" "unprognostic (4.50e-2)" "unprognostic (1.85e-2)" "prognostic favorable (3.83e-4)" "unprognostic (5.59e-2)" "unprognostic (5.61e-2)" "unprognostic (9.80e-3)" "unprognostic (3.99e-2)" "unprognostic (4.66e-2)" "unprognostic (6.23e-2)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (2.02e-1)" "prognostic favorable (9.25e-4)" "unprognostic (1.81e-1)" "unprognostic (8.48e-2)" "unprognostic (4.97e-3)" "unprognostic (9.46e-2)" LYSMD4 FLJ33008 ENSG00000183060 "LysM domain containing 4" Q5XG99 15 99715697-99733561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029152, HPA059824" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 21: Testis - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 55: Non-specific - Transcription" Cytosol "Actin filaments" "HPA029152: AB_10602033, HPA059824: AB_2684135" "unprognostic (2.43e-3)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (2.81e-1)" "unprognostic (4.07e-3)" "unprognostic (3.80e-2)" "unprognostic (1.53e-3)" "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (6.35e-3)" "unprognostic (9.77e-2)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (3.30e-1)" LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1;placenta: 144.3" "Group enriched" "Detected in many" 4 "Hofbauer cells: 713.2;Kupffer cells: 283.0;Lymphatic endothelial cells: 429.7;Macrophages: 217.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 2.4" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 58: Macrophages - Innate immune response" 21 "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" M6PR "CD-M6PR, CD-MPR" ENSG00000003056 "Mannose-6-phosphate receptor, cation dependent" P20645 12 8940361-8949761 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034464, HPA040445" Approved NA NA 100000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 5 "CAB034464: AB_2139108, HPA040445: AB_2676989" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.54e-1)" "unprognostic (3.00e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "unprognostic (5.82e-3)" "unprognostic (1.44e-2)" "unprognostic (6.82e-2)" "unprognostic (4.53e-3)" "unprognostic (3.79e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (3.98e-1)" MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA0754, KIAA1251, Lnc-PMIF, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1023.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 47: Astrocytes - Unknown function" 2 "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" MACO1 "FLJ10747, TMEM57" ENSG00000204178 "Macoilin 1" Q8N5G2 1 25430858-25500209 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019680 Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 19 Cytosol "HPA019680: AB_1858125" "unprognostic (2.42e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.83e-2)" "unprognostic (2.16e-1)" "unprognostic (1.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.69e-2)" "unprognostic (6.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (7.02e-2)" "prognostic favorable (7.13e-4)" "unprognostic (2.54e-2)" "unprognostic (4.22e-2)" "unprognostic (5.22e-2)" "unprognostic (5.35e-3)" MADCAM1 MACAM1 ENSG00000099866 "Mucosal vascular addressin cell adhesion molecule 1" Q13477 19 489176-505343 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.3;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.8;Endothelial cells: 5.1;Horizontal cells: 5.7;Muller glia cells: 5.5;Rod photoreceptor cells: 5.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "neutrophil: 7.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 7.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB075699, HPA077998" Enhanced NA NA 80000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Small intestine - Absorption" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "CAB075699: , HPA077998: " "unprognostic (2.30e-1)" "unprognostic (7.81e-2)" "unprognostic (5.52e-2)" "unprognostic (1.56e-1)" "unprognostic (7.56e-2)" "unprognostic (6.26e-4)" "unprognostic (1.68e-2)" "unprognostic (2.17e-4)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (2.44e-2)" "unprognostic (1.09e-1)" "unprognostic (2.54e-4)" "unprognostic (2.42e-1)" "unprognostic (4.95e-3)" "unprognostic (9.80e-2)" "unprognostic (2.07e-2)" MADD "DENN, KIAA0358, RAB3GEP" ENSG00000110514 "MAP kinase activating death domain" Q8WXG6 11 47269161-47330031 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Guanine-nucleotide releasing factor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 71.1;Cone photoreceptor cells: 129.1;Horizontal cells: 107.0;Rod photoreceptor cells: 99.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038568 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 2 "Plasma membrane, Cytosol" "HPA038568: AB_10795030" "unprognostic (3.16e-1)" "unprognostic (1.81e-1)" "unprognostic (8.51e-3)" "prognostic favorable (6.62e-5)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (4.82e-3)" "unprognostic (1.16e-1)" "unprognostic (1.91e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.69e-5)" "unprognostic (1.53e-1)" "unprognostic (3.55e-1)" "unprognostic (8.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" "prognostic favorable (8.25e-4)" MAG "GMA, S-MAG, SIGLEC-4A, SIGLEC4A" ENSG00000105695 "Myelin associated glycoprotein" P20916 19 35292125-35313807 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "brain: 682.0" "Group enriched" "Detected in some" 11 "Granulosa cells: 78.7;Oligodendrocytes: 249.3;Ovarian stromal cells: 89.9;Secretory cells: 77.3" "Cancer enriched" "Detected in some" 7 "glioma: 20.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enriched" "Detected in single" 8 "skin cancer: 7.6" "Kidney - Intercalated cells" "Region enhanced" "Detected in all" "white matter: 2743.6" "Low region specificity" "Detected in all" "CAB009345, HPA012499" Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" "CAB009345: AB_670104, HPA012499: AB_1854238" "unprognostic (2.70e-3)" "unprognostic (2.70e-2)" "unprognostic (8.06e-3)" "unprognostic (1.23e-1)" "unprognostic (6.93e-2)" "unprognostic (3.74e-1)" "unprognostic (1.50e-1)" "unprognostic (2.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (5.62e-2)" "unprognostic (5.18e-4)" "unprognostic (6.29e-2)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" "unprognostic (1.66e-1)" MAGEA4 "CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336" ENSG00000147381 "MAGE family member A4" P43358 X 151912495-151925171 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 21.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 20.7;Spermatocytes: 52.2;Spermatogonia: 196.7;Syncytiotrophoblasts: 35.7" "Cancer enhanced" "Detected in many" "lung cancer: 19.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 204.6" "Testis - Spermatogonia" "HPA021942, CAB040535" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Spermatogonia - Spermatogenesis" 16 "Nuclear speckles" Cytosol "CAB040535: , HPA021942: AB_1853490" "unprognostic (7.90e-3)" "unprognostic (6.66e-3)" "unprognostic (5.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-2)" "unprognostic (4.10e-1)" MAGED4 "KIAA1859, MAGE-E1, MAGE1, MGC3210" ENSG00000154545 "MAGE family member D4" Q96JG8 X 52184876-52192268 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.6;ovary: 14.5" "Cell type enhanced" "Detected in single" "Melanocytes: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 8.3;T-reg: 5.3" "Group enriched" "Detected in many" 53 "B-cells: 8.3;dendritic cells: 3.0;T-cells: 5.3" "Cancer enhanced" "Detected in many" "testis cancer: 50.3" HPA003554 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" 3 "HPA003554: AB_1853497" "unprognostic (7.71e-2)" "unprognostic (8.21e-2)" "unprognostic (4.07e-4)" "unprognostic (6.15e-2)" MAGED4B ENSG00000187243 "MAGE family member D4B" Q96JG8 X 52061827-52069219 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6;pituitary gland: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Group enriched" "Detected in many" 22 "B-cells: 2.3;dendritic cells: 4.6;T-cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 16.7" HPA003554 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 73: B-cells - B-cell function" 3 "HPA003554: AB_1853497" "unprognostic (7.75e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.01e-6)" "unprognostic (6.45e-2)" MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "epididymis: 503.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 57.6" "Breast - Fibroblasts, Kidney - Fibroblasts, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 7 "Nucleoli, Nucleoli rim" "HPA011324: AB_1853499, HPA011971: " "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.95e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-2)" "unprognostic (9.93e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "prognostic favorable (2.60e-4)" "unprognostic (6.37e-2)" "unprognostic (1.81e-2)" "unprognostic (1.29e-3)" "unprognostic (1.90e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77899271 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" Transport NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 1 "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2738.8;vagina: 837.1" "Cell type enriched" "Detected in many" 4 "Suprabasal keratinocytes: 1681.5" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 218.3;naive CD4 T-cell: 294.2;naive CD8 T-cell: 138.5;T-reg: 234.3" "Lineage enriched" "Detected in many" 38 "T-cells: 294.2" "Cancer enhanced" "Detected in many" "Leukemia: 35.0;ovarian cancer: 68.6;Uterine cancer: 46.9" "Adipose subcutaneous - Smooth muscle cells, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" 68 "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 252.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 390.8;Collecting duct cells: 334.5;Distal enterocytes: 359.9;Squamous epithelial cells: 320.2;Suprabasal keratinocytes: 583.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 37 "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 358.1;intestine: 228.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.3;Alveolar cells type 2: 238.9;Distal enterocytes: 653.1;Ductal cells: 277.7;Paneth cells: 207.2;Proximal enterocytes: 768.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.2;neutrophil: 2.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051410 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 51 "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" MALRD1 "bA265G8.2, C10orf112, Diet1" ENSG00000204740 "MAM and LDL receptor class A domain containing 1" Q5VYJ5 10 19048801-19790401 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 30.2" "Group enriched" "Detected in some" 4 "Astrocytes: 35.9;Oligodendrocyte precursor cells: 71.7;Proximal enterocytes: 62.0" "Cancer enhanced" "Detected in some" "breast cancer: 0.9;stomach cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;Myeloma: 2.0" "Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035732, HPA038106, HPA046848" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA035732: AB_2674756, HPA038106: AB_2675836, HPA046848: AB_2679837" "unprognostic (9.03e-3)" "unprognostic (1.38e-1)" "unprognostic (2.40e-2)" "unprognostic (4.05e-3)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (2.74e-2)" "unprognostic (5.57e-2)" "unprognostic (5.01e-1)" "unprognostic (1.00e-1)" "unprognostic (3.55e-1)" "unprognostic (7.69e-2)" "unprognostic (3.16e-2)" "unprognostic (9.80e-2)" "unprognostic (8.90e-2)" "unprognostic (3.13e-2)" "unprognostic (3.78e-4)" MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5;liver: 29.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.7;Hepatocytes: 20.4;Intestinal goblet cells: 23.3;Proximal enterocytes: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 69: Liver - Oxidoreductase activity" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "CAB026377: , HPA059977: AB_2684186" "unprognostic (2.79e-1)" "unprognostic (7.90e-2)" "unprognostic (4.09e-3)" "unprognostic (6.86e-2)" "unprognostic (8.33e-2)" "unprognostic (2.66e-4)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (7.37e-2)" "prognostic favorable (1.88e-6)" "unprognostic (8.22e-3)" "unprognostic (1.58e-2)" "unprognostic (1.22e-3)" "unprognostic (9.22e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 150.0" "Cell type enhanced" "Detected in many" "Early spermatids: 271.2;Hepatocytes: 219.4;Plasma cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 117.4" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 460000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "CAB037058: AB_477183, HPA053198: AB_2682078, HPA063561: AB_2685042" "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 280.3;Syncytiotrophoblasts: 414.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" NA NA 2000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus" "HPA034559: AB_10671229, HPA057364: AB_2683419" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (3.11e-2)" "unprognostic (9.70e-2)" "unprognostic (1.95e-2)" "unprognostic (8.01e-2)" "unprognostic (8.19e-3)" "prognostic favorable (4.08e-4)" "unprognostic (1.41e-1)" "unprognostic (4.38e-2)" "unprognostic (6.84e-2)" "unprognostic (1.45e-1)" "unprognostic (7.39e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-2)" MAN1B1 "ERMan1, ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086857-137109189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles NA NA 940000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA051516: AB_2681518" "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 76.5;Excitatory neurons: 70.4;Hepatocytes: 52.5;Inhibitory neurons: 63.3;Syncytiotrophoblasts: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" 2 "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689927-109869625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 1971.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" NA NA 110000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" MAN2A2 "HsT19662, MANA2X" ENSG00000196547 "Mannosidase alpha class 2A member 2" P49641 15 90902218-90922584 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 86.9;Oligodendrocytes: 86.2;Rod photoreceptor cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.8;neutrophil: 8.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077930 Approved "Cytoplasmic bodies" NA NA 43000000 "Cluster 20: Non-specific - DNA binding" "Cluster 3: Non-specific - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 51: Oligodendrocytes - Unknown function" "Cytoplasmic bodies" "HPA077930: AB_2732363" "unprognostic (5.17e-2)" "unprognostic (9.80e-2)" "unprognostic (2.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (5.06e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (8.95e-4)" "unprognostic (7.55e-3)" "unprognostic (1.13e-1)" "unprognostic (8.36e-2)" "unprognostic (2.33e-2)" MANBAL dJ1141E15.2 ENSG00000101363 "Mannosidase beta like" Q9NQG1 20 37289649-37317260 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 150.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052348 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Neuronal - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 4: Extravillous trophoblasts - Unknown function" 18 Mitochondria Nucleoplasm "HPA052348: AB_2681795" "unprognostic (1.86e-2)" "unprognostic (9.15e-2)" "unprognostic (1.85e-1)" "unprognostic (2.45e-2)" "unprognostic (3.12e-1)" "unprognostic (2.21e-3)" "prognostic unfavorable (7.07e-4)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (9.61e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "prognostic favorable (3.62e-4)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (8.03e-2)" "unprognostic (2.70e-2)" MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577485-95609470 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 46.1;Plasma cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favorable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 67.9" "Cell type enhanced" "Detected in many" "Serous glandular cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.6" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.6" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 134.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 44000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles "Golgi apparatus" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" MANSC4 ENSG00000205693 "MANSC domain containing 4" A6NHS7 12 27762427-27780236 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.0;testis: 1.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.6;Horizontal cells: 2.5;Rod photoreceptor cells: 1.2;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039454, HPA039682" Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 48: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA039454: AB_2676515, HPA039682: AB_10805483" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (2.34e-2)" "unprognostic (2.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-4)" "unprognostic (1.96e-1)" "unprognostic (2.49e-2)" "unprognostic (2.87e-3)" "unprognostic (2.50e-3)" "unprognostic (7.15e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-2)" MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746817 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 213.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 309.6;Proximal enterocytes: 817.1;Proximal tubular cells: 517.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.6;prostate cancer: 69.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970" "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 308.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 130.1;granulocytes: 213.3;Hepatocytes: 210.6;Ovarian stromal cells: 154.7;Proximal enterocytes: 179.7;Proximal tubular cells: 142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 36.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" 14 "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 197.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" 7 Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" MAPKAPK2 MK2 ENSG00000162889 "MAPK activated protein kinase 2" P49137 1 206684905-206734281 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 267.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in all" 6 "dendritic cells: 21.9" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 28: Dendritic cells - Antigen presentation" 4 Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: AB_2679367, HPA063708: AB_2685100, HPA064435: AB_2685263" "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 105.2;heart muscle: 248.1;skeletal muscle: 216.2;tongue: 273.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 233.9;Hofbauer cells: 112.4;monocytes: 201.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.9;granulocytes: 126.6;monocytes: 343.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" MAPKAPK5 "MK5, PRAK" ENSG00000089022 "MAPK activated protein kinase 5" Q8IW41 12 111842228-111902222 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 2 "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.6;retina: 22.3" "Cell type enhanced" "Detected in many" "B-cells: 226.2;Excitatory neurons: 466.6;Oligodendrocyte precursor cells: 929.6;Oligodendrocytes: 1211.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.4;myeloid DC: 44.2;naive B-cell: 35.9;non-classical monocyte: 45.6;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: AB_1853573, HPA048024: " "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" MARCHF2 "HSPC240, MARCH-II, MARCH2, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 57: Platelets - Hemostasis" 23 "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.48e-4)" "prognostic favorable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favorable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Microglial cells: 109.1;Spermatocytes: 70.9;Syncytiotrophoblasts: 87.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Astrocytes - Unknown function" 3 Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 7.7;pituitary gland: 6.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 44.3;Inhibitory neurons: 71.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 79.6" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" MARCHF5 "FLJ20445, MARCH-V, MARCH5, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291167-92353964 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" 25 Mitochondria "HPA056596: AB_2683181" "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" MARCHF6 "MARCH-VI, MARCH6, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353695-10440388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Endoplasmic reticulum" "HPA040841: AB_2677162, HPA063246: AB_2684970" "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" MARCHF8 "c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 308.4;Late spermatids: 406.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" 5 "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favorable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favorable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.1;lung: 193.5;lymphoid tissue: 85.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 176.7;Kupffer cells: 768.7;Macrophages: 229.5" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Region enhanced" "Detected in many" "thalamus: 28.0" "Group enriched" "Detected in some" 4 "classical monocyte: 33.8;intermediate monocyte: 56.6" "Lineage enriched" "Detected in many" 5 "monocytes: 56.6" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.2;lymphoma: 1.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385377-103503831 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 32 "eosinophil: 102.0" "Lineage enriched" "Detected in all" 32 "granulocytes: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Non-specific - Transcription" 9 "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" MARS1 "CMT2U, MARS, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase 1" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol NA NA 23000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Mixed function" 1 Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavorable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.3;Intestinal goblet cells: 61.6;Paneth cells: 92.8;Proximal enterocytes: 197.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" MAS1 ENSG00000130368 "MAS1 proto-oncogene, G protein-coupled receptor" P04201 6 159890988-159917447 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell type enhanced" "Detected in some" "B-cells: 1.9;Cone photoreceptor cells: 1.7;Langerhans cells: 2.1;Melanocytes: 1.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hippocampal formation: 23.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells" "Group enriched" "Detected in many" 22 "amygdala: 38.5;basal ganglia: 26.6;cerebral cortex: 32.4;hippocampal formation: 64.6;white matter: 18.1" "Group enriched" "Detected in some" 7 "amygdala: 7.9;cerebral cortex: 12.8;hippocampal formation: 25.7" HPA079325 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Fibroblasts - ECM organization" "HPA079325: " "unprognostic (3.31e-1)" "unprognostic (2.25e-3)" "unprognostic (2.91e-1)" "unprognostic (2.22e-3)" "unprognostic (8.15e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (6.52e-2)" "unprognostic (1.48e-5)" "unprognostic (1.69e-1)" "unprognostic (7.67e-2)" "unprognostic (6.28e-1)" MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 3.0;epididymis: 1.8" "Cell type enriched" "Detected in single" 18 "granulocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells" HPA017983 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017983: AB_1849332" "unprognostic (3.66e-2)" "unprognostic (2.51e-1)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (1.65e-1)" MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 95.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 20.0;Cone photoreceptor cells: 32.3;Excitatory neurons: 62.6;Horizontal cells: 39.7;Inhibitory neurons: 67.4;Oligodendrocyte precursor cells: 20.8" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 3 Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 83.1;Late spermatids: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Neurons - Neuronal signaling" 2 Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097778-18151692 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.5;Late spermatids: 31.4;monocytes: 37.1;Oligodendrocytes: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 1 "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favorable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 5: Enterocytes - Absorption" 25 Mitochondria "CAB009187: , HPA049850: AB_2680912, HPA053524: AB_2682177" "unprognostic (1.30e-2)" "unprognostic (4.51e-2)" "unprognostic (2.17e-1)" "unprognostic (6.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (2.30e-2)" "unprognostic (5.95e-2)" "prognostic favorable (3.81e-4)" "unprognostic (1.92e-1)" "prognostic favorable (4.13e-5)" "unprognostic (4.97e-2)" "unprognostic (3.03e-1)" "unprognostic (3.12e-2)" "unprognostic (7.39e-2)" MBOAT2 "FLJ14415, FLJ90298, LPLAT13, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 162.2;Erythroid cells: 117.7;Excitatory neurons: 129.9;Oligodendrocyte precursor cells: 166.5;Oligodendrocytes: 214.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" MBOAT4 "FKSG89, GOAT, OACT4" ENSG00000177669 "Membrane bound O-acyltransferase domain containing 4" Q96T53 8 30131671-30144665 "Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 3.4;stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Cholangiocytes: 7.6;Ductal cells: 3.6;Excitatory neurons: 2.4;Gastric mucus-secreting cells: 5.9;Inhibitory neurons: 2.9;Lymphatic endothelial cells: 2.7;Oligodendrocyte precursor cells: 2.8;Oligodendrocytes: 5.1;Schwann cells: 4.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044509 Supported "Golgi apparatus" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" "Golgi apparatus" "HPA044509: AB_2678966" "unprognostic (4.35e-3)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (3.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.76e-2)" "unprognostic (1.85e-3)" "unprognostic (4.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (6.30e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-6)" "unprognostic (9.87e-3)" "unprognostic (1.58e-1)" "unprognostic (2.18e-1)" "unprognostic (3.66e-2)" MBOAT7 "BB1, hMBOA-7, LENG4, LPIAT1, LPLAT, LPLAT11" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 105.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "basophil: 157.4;eosinophil: 265.9;neutrophil: 239.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" 2 Cytosol "HPA055967: AB_2682990" "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (5.55e-6)" "prognostic unfavorable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favorable (4.31e-4)" MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116942 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Retina & Testis - Cilium" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 66: Photoreceptor cells - Visual perception" "HPA056109: AB_2683040" "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favorable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" MC2R ACTHR ENSG00000185231 "Melanocortin 2 receptor" Q01718 18 13882044-13915707 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "adrenal gland: 56.1" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079148 Enhanced NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA079148: " "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.85e-2)" MC3R MC3 ENSG00000124089 "Melanocortin 3 receptor" P41968 20 56248732-56249815 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "hypothalamus: 31.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 4.8;hypothalamus: 4.5;thalamus: 1.3" "Group enriched" "Detected in some" 5 "basal ganglia: 4.2;hypothalamus: 2.8;thalamus: 3.3" HPA074739 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 21: Early spermatids - Spermatogenesis" "HPA074739: " MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 3.4;fallopian tube: 2.9;retina: 3.8" "Group enriched" "Detected in some" 5 "Bipolar cells: 7.0;Cone photoreceptor cells: 5.1" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.5" HPA016719 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.6;lymphoid tissue: 1.0" "Group enriched" "Detected in some" 4 "Late spermatids: 6.5;Squamous epithelial cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 116.4;Endothelial cells: 105.5;Muller glia cells: 82.4;Sertoli cells: 193.1;Smooth muscle cells: 416.8" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 283.7" "Colon - Smooth muscle cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Supported "Plasma membrane" NA NA 1900000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7677088-7679829 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 81.0;lung: 85.3;lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 73.0;Kupffer cells: 31.6;Langerhans cells: 20.3;Macrophages: 114.3;monocytes: 29.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Group enriched" "Detected in some" 5 "cerebral cortex: 6.2;pons: 2.8;thalamus: 2.9" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;neutrophil: 57.5" "Group enriched" "Detected in many" 5 "granulocytes: 57.5;monocytes: 124.0" "Cancer enriched" "Detected in some" 6 "Leukemia: 17.5" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 8 "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 676.9" "Cell type enhanced" "Detected in all" "monocytes: 1334.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 13 Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin TRP cation channel 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 101.6;Kupffer cells: 88.5;Macrophages: 74.1;monocytes: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 118.2;classical monocyte: 45.3;eosinophil: 106.1;intermediate monocyte: 95.7;neutrophil: 41.4;non-classical monocyte: 105.7" "Group enriched" "Detected in all" 5 "granulocytes: 118.2;monocytes: 105.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 2 "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" MCOLN2 "FLJ36691, TRP-ML2, TRPML2" ENSG00000153898 "Mucolipin TRP cation channel 2" Q8IZK6 1 84925583-84997113 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Innate immunity, Ion transport, Protein transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.5;intestine: 14.6;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in many" "B-cells: 40.1;dendritic cells: 79.7;Early spermatids: 67.0;Glandular and luminal cells: 27.3;Langerhans cells: 114.9;Schwann cells: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.6" "Group enriched" "Detected in many" 15 "B-cells: 10.3;dendritic cells: 29.6;T-cells: 8.8" "Cancer enriched" "Detected in many" 5 "lymphoma: 27.9" "Adipose subcutaneous - T-cells, Liver - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019114 Uncertain NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA019114: AB_1853645" "unprognostic (3.02e-2)" "unprognostic (5.67e-2)" "unprognostic (3.07e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.38e-1)" "prognostic favorable (2.56e-4)" "unprognostic (8.92e-2)" "unprognostic (1.48e-2)" "unprognostic (6.84e-2)" "unprognostic (2.21e-2)" "unprognostic (3.12e-4)" "unprognostic (3.68e-2)" "unprognostic (4.69e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-2)" MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin TRP cation channel 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 42.4;epididymis: 13.8;parathyroid gland: 34.1" "Group enriched" "Detected in many" 6 "Enteroendocrine cells: 53.4;Melanocytes: 211.3" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in many" 5 "cerebral cortex: 8.3;choroid plexus: 7.4;hippocampal formation: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Lung - Fibroblast_1, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.2" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703690-95285094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.8" "Cell type enhanced" "Detected in many" "Adipocytes: 111.4;Excitatory neurons: 493.2;Inhibitory neurons: 394.8;monocytes: 119.7;Oligodendrocyte precursor cells: 247.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 45 "basophil: 37.1;classical monocyte: 28.7;eosinophil: 13.3;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.7;non-classical monocyte: 40.8;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.7;monocytes: 41.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075887 Approved "Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA075887: " "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" MCTP2 "FLJ11175, FLJ33303" ENSG00000140563 "Multiple C2 and transmembrane domain containing 2" Q6DN12 15 94231538-94483952 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "granulocytes: 73.5;NK-cells: 131.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA051176, HPA070541" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" "Nucleoplasm, Cytosol" "HPA051176: AB_2681373, HPA070541: AB_2686277" "unprognostic (1.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.63e-2)" "unprognostic (7.15e-4)" "unprognostic (3.57e-2)" "unprognostic (2.66e-3)" "unprognostic (3.45e-2)" "unprognostic (3.68e-3)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (5.87e-2)" "unprognostic (4.36e-1)" "unprognostic (1.76e-3)" "unprognostic (9.41e-2)" MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692143-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 52.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.2;Gastric mucus-secreting cells: 67.8;Inhibitory neurons: 62.9;Oligodendrocyte precursor cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 17000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 2 Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favorable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.5;Extravillous trophoblasts: 96.4;Hofbauer cells: 123.4;Oocytes: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048776 Enhanced Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" "Nucleoplasm, Vesicles, Mitochondria" "HPA048776: AB_2680518" "unprognostic (6.12e-3)" "unprognostic (1.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-3)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.35e-6)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" MCUR1 "C6orf79, CCDC90A, FLJ20958" ENSG00000050393 "Mitochondrial calcium uniporter regulator 1" Q96AQ8 6 13786557-13814568 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 79.1" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 211.5;Rod photoreceptor cells: 253.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078654 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" "HPA078654: " "unprognostic (1.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-3)" "unprognostic (8.62e-2)" "unprognostic (2.25e-3)" "unprognostic (2.01e-3)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "prognostic favorable (5.51e-4)" "unprognostic (3.40e-1)" "unprognostic (5.77e-2)" "prognostic favorable (3.32e-4)" "unprognostic (5.86e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-2)" "unprognostic (2.39e-1)" MDFIC "HIC, MDFIC1" ENSG00000135272 "MyoD family inhibitor domain containing" Q9P1T7 7 114922094-115019917 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 93.1;Muller glia cells: 104.6;T-cells: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030716 Approved Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Transcription NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Nucleoplasm, Golgi apparatus" "HPA030716: AB_10671364" "unprognostic (1.24e-3)" "unprognostic (4.15e-1)" "unprognostic (2.38e-2)" "unprognostic (2.29e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-3)" "unprognostic (1.73e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (8.02e-2)" "unprognostic (6.38e-3)" "unprognostic (3.68e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (6.13e-3)" "unprognostic (7.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.55e-1)" MDGA2 MAMDC1 ENSG00000139915 "MAM domain containing glycosylphosphatidylinositol anchor 2" Q7Z553 14 46839629-47675605 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 3.5;retina: 4.3;testis: 3.7" "Group enriched" "Detected in some" 7 "Excitatory neurons: 1504.9;Inhibitory neurons: 1159.8;Oligodendrocyte precursor cells: 1851.3" "Cancer enhanced" "Detected in single" "melanoma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.2" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003084 Uncertain NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA003084: AB_1079302" "unprognostic (3.27e-1)" "unprognostic (5.38e-2)" "unprognostic (9.13e-2)" "unprognostic (8.92e-3)" "unprognostic (6.36e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.49e-3)" "unprognostic (3.62e-3)" "unprognostic (3.06e-2)" "unprognostic (5.89e-1)" MDM1 ENSG00000111554 "Mdm1 nuclear protein" Q8TC05 12 68272443-68332381 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040411, HPA041594" Uncertain Supported "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 1 "Centriolar satellite" Cytosol "HPA040411: AB_10805711, HPA041594: AB_10793968" "unprognostic (7.41e-2)" "prognostic favorable (6.01e-4)" "unprognostic (8.58e-2)" "unprognostic (2.62e-3)" "unprognostic (1.21e-1)" "unprognostic (3.50e-3)" "unprognostic (4.24e-3)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" "unprognostic (2.92e-1)" "unprognostic (2.56e-3)" "unprognostic (3.13e-2)" "unprognostic (4.29e-3)" "unprognostic (1.29e-1)" "unprognostic (2.84e-1)" "unprognostic (4.63e-2)" "unprognostic (5.23e-3)" MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 6 "Nuclear speckles" Cytosol "HPA046619: " "prognostic unfavorable (4.94e-4)" "unprognostic (2.92e-1)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.48e-3)" "unprognostic (7.73e-2)" "unprognostic (1.41e-1)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.22e-1)" "unprognostic (5.56e-3)" "unprognostic (1.48e-1)" MED23 "CRSP130, CRSP3, DRIP130, MRT18, Sur2" ENSG00000112282 "Mediator complex subunit 23" Q9ULK4 6 131573966-131628242 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 69.5;Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070341 Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 3: Basal prostatic cells - Lipid metabolism" 6 "Nucleoplasm, Vesicles" "HPA070341: AB_2686257" "unprognostic (1.11e-2)" "unprognostic (4.66e-2)" "unprognostic (5.51e-3)" "unprognostic (1.80e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (6.62e-3)" "unprognostic (4.47e-1)" "unprognostic (1.64e-1)" "unprognostic (6.81e-3)" "unprognostic (1.44e-2)" "unprognostic (3.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.82e-2)" "unprognostic (2.21e-1)" "unprognostic (2.44e-2)" "unprognostic (2.53e-2)" MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.9;retina: 7.8" "Group enriched" "Detected in some" 4 "Astrocytes: 207.1;Oligodendrocyte precursor cells: 91.5;Oligodendrocytes: 355.2" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Sarcoma: 10.0;skin cancer: 6.9" "Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011401 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 73000000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "HPA011401: " "unprognostic (7.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.26e-3)" "unprognostic (8.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-4)" "unprognostic (5.28e-3)" "unprognostic (2.59e-1)" "unprognostic (9.36e-4)" "unprognostic (1.17e-1)" MEGF8 "C19orf49, EGFL4, FLJ22365, SBP1" ENSG00000105429 "Multiple EGF like domains 8" Q7Z7M0 19 42325609-42378769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.2;Horizontal cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049248 Approved NA NA 510000000 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "HPA049248: AB_2680691" "unprognostic (5.52e-3)" "unprognostic (1.52e-1)" "unprognostic (5.35e-2)" "unprognostic (1.66e-2)" "unprognostic (1.20e-1)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (8.58e-2)" "unprognostic (9.25e-2)" "unprognostic (3.64e-2)" "prognostic favorable (6.03e-4)" "unprognostic (4.33e-2)" "prognostic favorable (2.17e-7)" "unprognostic (1.18e-1)" "unprognostic (7.34e-2)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" MEGF9 EGFL5 ENSG00000106780 "Multiple EGF like domains 9" Q9H1U4 9 120600811-120714470 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 66.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 217.3;Alveolar cells type 2: 160.4;Astrocytes: 135.6;Cone photoreceptor cells: 246.4;Oligodendrocytes: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.2" "Group enriched" "Detected in many" 5 "granulocytes: 25.2;monocytes: 7.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014319, HPA050238" Approved Approved Nucleoplasm,Cytosol NA NA 96000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 74: Neutrophils - Degranulation" Nucleoplasm Cytosol "HPA014319: AB_1848035, HPA050238: AB_2681060" "unprognostic (1.18e-1)" "unprognostic (5.33e-2)" "unprognostic (1.84e-1)" "unprognostic (1.75e-2)" "unprognostic (3.30e-1)" "unprognostic (3.68e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-2)" "unprognostic (3.63e-2)" "unprognostic (1.13e-2)" "unprognostic (5.92e-2)" "unprognostic (4.97e-2)" "prognostic favorable (5.48e-11)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "unprognostic (6.78e-2)" "unprognostic (1.41e-1)" MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 20.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.8;Erythroid cells: 18.0;Extravillous trophoblasts: 46.8;Spermatocytes: 23.7;Spermatogonia: 19.3;Undifferentiated cells: 20.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA017214 Uncertain NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Non-specific - Cell proliferation" 1 "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 67.2;Excitatory neurons: 111.1;Inhibitory neurons: 106.5;Microglial cells: 95.7;Oligodendrocyte precursor cells: 99.5;Oligodendrocytes: 125.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 9100 "Cluster 25: Non-specific - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 76: Oligodendrocyte precursor - Unknown function" 16 Vesicles "HPA042603: AB_10806243, HPA057952: AB_2683562" "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.94e-5)" "unprognostic (1.02e-2)" "unprognostic (3.96e-2)" "unprognostic (2.24e-4)" "unprognostic (1.70e-2)" "unprognostic (6.73e-2)" "unprognostic (8.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (5.95e-9)" "unprognostic (6.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.77e-2)" "unprognostic (4.23e-2)" MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793389-46839778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "intestine: 454.9" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 799.3" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 38.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 8.0;Gastric cancer: 3.2;liver cancer: 9.0" "Colon - Colon enterocytes, Testis - Late spermatids" "CAB025163, HPA029416" Enhanced NA NA 2100000 "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "CAB025163: , HPA029416: AB_10600823" "unprognostic (1.83e-1)" "unprognostic (2.81e-4)" "unprognostic (2.03e-1)" "unprognostic (8.53e-2)" "unprognostic (8.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (5.27e-4)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.91e-2)" "unprognostic (4.70e-3)" "unprognostic (1.68e-1)" MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "intestine: 353.8" "Cell type enriched" "Detected in some" 50 "Proximal enterocytes: 199.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.1;Myeloma: 2.3" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029119 Enhanced "Secreted to digestive system" Enzyme NA NA 310000 "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 154.2;Kupffer cells: 106.1;Macrophages: 62.0;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "intermediate monocyte: 8.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 95.5;Cytotrophoblasts: 75.8;Glandular and luminal cells: 138.4;Mesothelial cells: 72.0;Salivary duct cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 289.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 179000000 100000000 "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 16 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" METTL21A "FAM119A, HCA557b, HSPA-KMT, LOC151194" ENSG00000144401 "Methyltransferase 21A, HSPA lysine" Q8WXB1 2 207580631-207625928 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 94.8;Langerhans cells: 101.8;Paneth cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 30: Granulocytes - Unknown function" 10 Nucleoplasm Cytosol "HPA034712: AB_10670160" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (4.56e-2)" "unprognostic (2.09e-3)" "unprognostic (2.00e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (4.80e-2)" "unprognostic (2.30e-2)" "unprognostic (2.47e-3)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (5.43e-4)" "unprognostic (5.01e-2)" "unprognostic (3.05e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" METTL25B "C1orf66, CGI-41, RRNAD1" ENSG00000143303 "Methyltransferase like 25B" Q96FB5 1 156728442-156736960 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047426 Approved Approved Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoli Cytosol "HPA047426: AB_2680041" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (2.00e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-1)" "unprognostic (2.89e-3)" "unprognostic (2.24e-1)" "unprognostic (2.76e-1)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (1.49e-1)" "unprognostic (5.03e-3)" METTL7A DKFZP586A0522 ENSG00000185432 "Methyltransferase like 7A" Q9H8H3 12 50923472-50932510 "Predicted membrane proteins" "Host-virus interaction" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 802.8;Kupffer cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 94.8;classical monocyte: 34.9;eosinophil: 69.9;intermediate monocyte: 37.4;memory B-cell: 31.8;myeloid DC: 30.4;naive B-cell: 34.1;non-classical monocyte: 59.0;plasmacytoid DC: 25.0" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 88.0" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017434 Supported "Lipid droplets" NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 "Lipid droplets" "HPA017434: AB_1853835" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" "unprognostic (9.85e-3)" "unprognostic (9.43e-2)" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.09e-3)" "unprognostic (2.68e-3)" "unprognostic (5.48e-2)" "unprognostic (9.94e-2)" "unprognostic (2.57e-2)" "unprognostic (4.49e-2)" "prognostic favorable (0.00e+0)" "unprognostic (8.64e-2)" "unprognostic (5.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-2)" MFAP3 ENSG00000037749 "Microfibril associated protein 3" P55082 5 154038959-154220478 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015883, HPA049198" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 5: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" Nucleoplasm "HPA015883: AB_1853840, HPA049198: AB_2680672" "unprognostic (6.02e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (1.58e-3)" "unprognostic (2.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (6.58e-3)" "unprognostic (1.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.53e-2)" "unprognostic (7.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (9.35e-3)" MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 45.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1849.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Testis - Spermatid development" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "Cell Junctions" "HPA017986: AB_1853842, HPA062306: , HPA077490: AB_2686842" "unprognostic (8.04e-3)" "unprognostic (8.67e-3)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-1)" "unprognostic (7.58e-2)" "prognostic favorable (1.42e-8)" "unprognostic (6.59e-3)" "unprognostic (2.12e-1)" "unprognostic (1.62e-4)" "unprognostic (2.40e-3)" MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357833 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1011.1;Late spermatids: 1782.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010968, HPA074625" Enhanced Supported Mitochondria No No 62000 "Cluster 22: Eosinophils - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 36: Late spermatids - Unknown function" 1 Mitochondria "HPA010968: AB_1845714, HPA074625: AB_2686704" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.07e-2)" "unprognostic (1.32e-1)" "unprognostic (6.07e-2)" "unprognostic (3.00e-2)" "unprognostic (6.24e-3)" "unprognostic (5.50e-2)" "unprognostic (1.00e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" "unprognostic (3.22e-1)" MFN1 FLJ20693 ENSG00000171109 "Mitofusin 1" Q8IWA4 3 179347709-179394936 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033437, HPA059230" Approved Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Neurons - Neuronal signaling" 1 Mitochondria "CAB033437: AB_2250540, HPA059230: AB_2683952" "unprognostic (2.94e-2)" "unprognostic (5.56e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (6.70e-4)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (6.37e-2)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "unprognostic (3.76e-3)" "unprognostic (7.91e-2)" "unprognostic (7.90e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-1)" "unprognostic (6.24e-2)" "unprognostic (9.79e-2)" MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 260.9;skeletal muscle: 299.6;tongue: 324.2" "Cell type enriched" "Detected in all" 6 "Cardiomyocytes: 398.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 Mitochondria "CAB079902: AB_2724683, HPA030554: AB_10603018" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-2)" "unprognostic (8.36e-2)" "unprognostic (9.71e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (3.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.43e-1)" "unprognostic (3.55e-1)" "prognostic favorable (2.36e-8)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" "unprognostic (8.84e-3)" "unprognostic (2.12e-1)" MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 213.6;Kupffer cells: 274.6;Macrophages: 189.7;monocytes: 202.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.7;granulocytes: 246.6;monocytes: 289.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Lung - Lung function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" MFSD10 "IT10C3, TETRAN" ENSG00000109736 "Major facilitator superfamily domain containing 10" Q14728 4 2930561-2934834 "Predicted membrane proteins" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 238.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043209 Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Nuclear membrane" Nucleoplasm "HPA043209: AB_2678364" "unprognostic (1.44e-1)" "unprognostic (2.26e-2)" "unprognostic (7.06e-2)" "unprognostic (2.11e-3)" "unprognostic (7.76e-2)" "unprognostic (9.43e-2)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.82e-3)" "unprognostic (4.70e-3)" "unprognostic (3.21e-1)" "unprognostic (1.91e-2)" "unprognostic (5.42e-3)" "prognostic unfavorable (5.68e-5)" "unprognostic (8.32e-2)" "unprognostic (2.30e-1)" "unprognostic (8.03e-2)" "unprognostic (1.00e-2)" MFSD11 "FLJ20226, FLJ22196" ENSG00000092931 "Major facilitator superfamily domain containing 11" O43934 17 76735865-76781449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 142.7;Early spermatids: 117.2;Late spermatids: 229.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022001 Uncertain NA No "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" 4 "HPA022001: AB_2297599" "unprognostic (2.84e-2)" "unprognostic (1.22e-1)" "unprognostic (2.43e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-3)" "unprognostic (1.68e-2)" "unprognostic (2.06e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-1)" "unprognostic (1.18e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.90e-4)" MFSD12 "C19orf28, MGC20700, PP3501" ENSG00000161091 "Major facilitator superfamily domain containing 12" Q6NUT3 19 3538261-3574290 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Melanin biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 166.8;Melanocytes: 307.5;monocytes: 155.7;Syncytiotrophoblasts: 121.8" "Cancer enriched" "Detected in all" 7 "melanoma: 124.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in all" 4 "Adrenocortical cancer: 183.3;skin cancer: 635.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042149, HPA043088" Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 33: Non-specific - DNA binding" "HPA042149: AB_2677875, HPA043088: AB_2678308" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "prognostic favorable (5.66e-6)" "unprognostic (1.56e-2)" "unprognostic (6.51e-2)" "prognostic unfavorable (6.61e-4)" "prognostic unfavorable (2.34e-4)" "unprognostic (3.19e-2)" "unprognostic (9.12e-3)" "unprognostic (1.56e-2)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.70e-4)" "unprognostic (1.95e-1)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" MFSD13A "bA18I14.8, C10orf77, FLJ22529, TMEM180" ENSG00000138111 "Major facilitator superfamily domain containing 13A" Q14CX5 10 102461395-102477045 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.3;Syncytiotrophoblasts: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018031 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" 3 "Golgi apparatus, Cytosol" "HPA018031: AB_2204891" "unprognostic (2.24e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.79e-1)" "unprognostic (2.11e-1)" "unprognostic (9.16e-3)" "unprognostic (4.70e-2)" "unprognostic (4.03e-2)" "unprognostic (8.10e-2)" "unprognostic (2.04e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.66e-3)" "unprognostic (2.44e-1)" "unprognostic (2.74e-1)" "unprognostic (4.02e-2)" MFSD14A "DKFZP564L0864, HIAT1" ENSG00000156875 "Major facilitator superfamily domain containing 14A" Q96MC6 1 100038095-100083377 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 127.2" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Basal squamous epithelial cells: 32.4;Excitatory neurons: 34.6;Inhibitory neurons: 35.4;Oligodendrocyte precursor cells: 34.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 187.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073127, HPA073681" Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" Vesicles "HPA073127: , HPA073681: AB_2686625" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (2.16e-1)" "unprognostic (7.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (3.84e-1)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" MFSD14B "FLJ14753, HIATL1" ENSG00000148110 "Major facilitator superfamily domain containing 14B" Q5SR56 9 94374569-94461042 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017978 Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Monocytes - Innate immune response" 61 "Nucleoplasm, Cytosol" "HPA017978: AB_2116836" "unprognostic (3.03e-2)" "unprognostic (2.28e-1)" "unprognostic (3.96e-3)" "unprognostic (5.95e-3)" "unprognostic (1.39e-1)" "unprognostic (3.29e-2)" "unprognostic (4.13e-3)" "unprognostic (3.27e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-2)" "unprognostic (1.16e-2)" "unprognostic (3.11e-3)" "unprognostic (1.15e-1)" "unprognostic (9.12e-2)" "unprognostic (6.63e-2)" "unprognostic (1.93e-1)" "unprognostic (9.01e-2)" MFSD2A "FLJ14490, MFSD2, SLC59A1" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 95.3;liver: 158.0;skin 1: 85.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 297.1;Basal prostatic cells: 213.4;Hepatocytes: 290.7;Proximal enterocytes: 201.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 12 "dendritic cells: 24.4;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" MFSD2B SLC59A2 ENSG00000205639 "Major facilitator superfamily domain containing 2B" A6NFX1 2 24010081-24063321 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "bone marrow: 11.7" "Cell type enriched" "Detected in some" 8 "Erythroid cells: 49.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.9" "Cancer enriched" "Detected in single" 16 "Leukemia: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044145 Enhanced NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "HPA044145: AB_2678833" "unprognostic (5.67e-2)" "unprognostic (1.25e-3)" "unprognostic (1.84e-1)" "unprognostic (5.35e-5)" "unprognostic (2.82e-1)" "unprognostic (1.74e-1)" "unprognostic (4.26e-2)" "unprognostic (7.47e-2)" "unprognostic (2.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.21e-3)" "unprognostic (1.90e-2)" "unprognostic (6.87e-6)" "unprognostic (7.76e-2)" "unprognostic (1.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.72e-1)" MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 5 Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, SLC60A1, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.3;kidney: 64.4;stomach 1: 129.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 107.3;Distal enterocytes: 44.1;Excitatory neurons: 46.6;Gastric mucus-secreting cells: 31.8;Glandular and luminal cells: 40.2;Intestinal goblet cells: 41.3;Ionocytes: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Ascending Loop of Henle cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 19.6;cerebellum: 25.5;cerebral cortex: 77.8;hippocampal formation: 43.0" HPA055407 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" MFSD4B "KIAA1919, MGC33953, SLC60A2" ENSG00000173214 "Major facilitator superfamily domain containing 4B" Q5TF39 6 111259327-111445354 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 82.0;Rod photoreceptor cells: 80.1;Syncytiotrophoblasts: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031784 Approved "Intracellular and membrane" Transport NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Non-specific - Transcription" 2 "HPA031784: AB_10603775" "unprognostic (2.98e-2)" "unprognostic (1.64e-2)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (7.50e-5)" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (6.84e-2)" "unprognostic (2.94e-2)" "unprognostic (3.41e-1)" "unprognostic (6.04e-3)" "unprognostic (9.27e-2)" "unprognostic (3.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.98e-4)" MFSD5 "HsMOT2, MGC11308, SLC61A1" ENSG00000182544 "Major facilitator superfamily domain containing 5" Q6N075 12 53251251-53254406 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039773 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 59: Suprabasal keratinocytes - Cornification" 46 "HPA039773: AB_10793920" "unprognostic (9.42e-3)" "unprognostic (9.03e-3)" "unprognostic (4.25e-2)" "unprognostic (1.10e-1)" "unprognostic (1.37e-2)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (2.20e-2)" "unprognostic (1.69e-1)" "unprognostic (4.25e-1)" "unprognostic (9.79e-2)" "unprognostic (4.52e-2)" "unprognostic (5.63e-2)" "unprognostic (1.65e-2)" "unprognostic (2.12e-1)" "unprognostic (6.51e-3)" "unprognostic (1.19e-2)" MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 83.4;Oligodendrocytes: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 80: Non-specific - Endocytosis" "Cluster 45: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 31 "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" MFSD6L FLJ35773 ENSG00000185156 "Major facilitator superfamily domain containing 6 like" Q8IWD5 17 8797110-8799365 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 9.1;testis: 24.8" "Group enriched" "Detected in many" 9 "Early spermatids: 121.1;Late spermatids: 62.8;Spermatocytes: 36.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" HPA023164 Uncertain NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA023164: AB_2142777" "prognostic favorable (1.84e-4)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (3.64e-2)" "unprognostic (1.07e-4)" "unprognostic (3.31e-1)" "unprognostic (1.33e-1)" "unprognostic (2.32e-1)" "unprognostic (2.77e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" "unprognostic (7.26e-2)" "unprognostic (3.98e-3)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (7.68e-3)" "unprognostic (1.25e-1)" MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Vesicles Nucleoplasm "HPA044802: AB_10963221" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (8.10e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-3)" "unprognostic (3.14e-1)" "prognostic favorable (2.21e-4)" MFSD9 MGC11332 ENSG00000135953 "Major facilitator superfamily domain containing 9" Q8NBP5 2 102714630-102736888 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055293, HPA061859" Approved Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoli, Nucleoli rim" "HPA055293: AB_2682775, HPA061859: AB_2684627" "unprognostic (1.27e-2)" "unprognostic (5.07e-2)" "unprognostic (5.00e-2)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-1)" "unprognostic (2.60e-2)" "unprognostic (2.98e-1)" "unprognostic (1.06e-1)" "unprognostic (8.42e-2)" "unprognostic (6.88e-3)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (3.33e-1)" "unprognostic (2.28e-2)" MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 24.9;intestine: 85.2" "Group enriched" "Detected in some" 7 "Late spermatids: 157.6;Proximal enterocytes: 502.3" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.5" "Lineage enriched" "Detected in single" 102 "granulocytes: 13.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9;skin cancer: 4.3" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Region enriched" "Detected in single" 12 "olfactory bulb: 2.0" "Low region specificity" "Detected in all" HPA002270 Enhanced NA NA 310000 "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 5 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111718-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.7;pancreas: 3.9;salivary gland: 8.4" "Group enriched" "Detected in some" 4 "Early spermatids: 28.6;Late spermatids: 18.4;Mucus glandular cells: 10.9;Serous glandular cells: 9.7" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 16.4;Gastric cancer: 7.4;skin cancer: 5.6" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Lung - Neutrophil_2, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles Cytosol "HPA055697: AB_2682890" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.0;retina: 113.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 124.4;Horizontal cells: 114.6;Muller glia cells: 447.6" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Rhabdoid: 47.0" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 28.0" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 14 Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" P26572 5 180784780-180815652 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 311.5;monocytes: 410.2;Syncytiotrophoblasts: 506.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved NA NA 12000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 1 "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.4;epididymis: 4.5;testis: 4.6;thyroid gland: 5.8" "Group enriched" "Detected in some" 8 "Astrocytes: 831.1;Excitatory neurons: 954.0;Inhibitory neurons: 1374.8" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Neuroblastoma: 1.3;testis cancer: 2.7" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: AB_2732416" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" MGAT5 "GNT-V, MGAT5A" ENSG00000152127 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.7;Inhibitory neurons: 129.3;Microglial cells: 135.1;Oligodendrocyte precursor cells: 117.0;Oligodendrocytes: 461.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved "Intracellular and membrane" Enzyme NA NA 440000 "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 51: Oligodendrocytes - Unknown function" "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "brain: 41.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.2;Cone photoreceptor cells: 10.2;Excitatory neurons: 25.3;Horizontal cells: 9.4;Inhibitory neurons: 21.0;Late spermatids: 9.5;Oocytes: 63.2" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: AB_2668423" "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" MGST1 "GST12, MGST-I, PMAN" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1058.2;adrenal gland: 1101.6;liver: 3006.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1610.1;Basal respiratory cells: 1196.1;Hepatocytes: 4650.4;Proximal tubular cells: 1122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 171.3;myeloid DC: 124.0" "Group enriched" "Detected in many" 13 "dendritic cells: 124.0;monocytes: 171.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 83: Liver - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" 5 Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 380.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 453.5;Proximal enterocytes: 443.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 195.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 22 Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2171.2;Extravillous trophoblasts: 1454.9;Syncytiotrophoblasts: 2374.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 79 Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 131.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "choroid plexus: 135.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 75: Serous glandular cells - Salivary secretion" 7 "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Deafness, Diabetes mellitus, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 1400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 55: Non-specific - Transcription" 7 Vesicles "HPA055922: AB_2682971, HPA056816: AB_2683243" "unprognostic (1.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (5.65e-2)" "unprognostic (6.73e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.83e-1)" "unprognostic (8.62e-3)" "unprognostic (3.26e-1)" MICAL2 "FLJ14966, KIAA0750, MICALCL" ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 199.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 150.0;Excitatory neurons: 187.1;Inhibitory neurons: 104.5;Late spermatids: 229.3;Peritubular cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 16: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" 8 "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 170.5;Inhibitory neurons: 157.6;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 11.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 32: Basophils - Transcription" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" MICB PERB11.2 ENSG00000204516 "MHC class I polypeptide-related sequence B" Q29980 6 31494881-31511124 "Disease related genes, Predicted membrane proteins" "Adaptive immunity, Cytolysis, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 12.8;Kupffer cells: 12.4;NK-cells: 10.2;Plasma cells: 8.9;T-cells: 10.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA064618 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 52: Non-specific - Cell proliferation" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA064618: AB_2685301" "unprognostic (3.63e-3)" "unprognostic (8.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (8.44e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (7.04e-5)" "unprognostic (2.05e-1)" "unprognostic (2.61e-1)" "unprognostic (1.67e-3)" "unprognostic (2.28e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (4.94e-9)" "unprognostic (1.91e-3)" "unprognostic (2.80e-2)" "unprognostic (9.72e-2)" "unprognostic (1.21e-2)" MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 896.1;Distal tubular cells: 1051.1;Proximal tubular cells: 977.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "HPA059930: AB_2684167" "unprognostic (3.84e-2)" "unprognostic (8.74e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (8.74e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.24e-3)" "unprognostic (7.13e-2)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "prognostic favorable (8.11e-4)" MICU3 "DKFZp313A0139, EFHA2" ENSG00000155970 "Mitochondrial calcium uptake family member 3" Q86XE3 8 17027238-17122642 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 75.1;Excitatory neurons: 156.0;Inhibitory neurons: 160.2;Oligodendrocyte precursor cells: 90.6;Oligodendrocytes: 132.1;Rod photoreceptor cells: 83.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024771, HPA024779" Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA024771: AB_1848022, HPA024779: AB_1848023" "unprognostic (2.99e-2)" "unprognostic (7.73e-2)" "unprognostic (7.88e-2)" "unprognostic (3.80e-2)" "unprognostic (1.19e-1)" "unprognostic (7.49e-2)" "unprognostic (2.25e-2)" "unprognostic (9.01e-5)" "unprognostic (9.82e-2)" "unprognostic (2.80e-1)" "unprognostic (1.11e-3)" "unprognostic (8.45e-2)" "unprognostic (2.32e-2)" "unprognostic (3.03e-3)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (4.65e-2)" MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 122.6;Basal squamous epithelial cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 27 "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" MIEF1 "FLJ20232, L0R8F8, MiD51, SMCR7L" ENSG00000100335 "Mitochondrial elongation factor 1" Q9NQG6 22 39499432-39518132 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 214.3;Late spermatids: 410.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061059 Uncertain "Intermediate filaments,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 13: Spermatids - Transcription" 19 "Intermediate filaments, Mitochondria" "HPA061059: " "unprognostic (5.35e-2)" "unprognostic (2.66e-2)" "unprognostic (2.86e-3)" "unprognostic (1.11e-2)" "unprognostic (3.74e-2)" "unprognostic (1.49e-1)" "unprognostic (1.95e-3)" "unprognostic (1.85e-2)" "unprognostic (5.72e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (6.65e-2)" "prognostic favorable (3.96e-5)" "unprognostic (1.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.30e-1)" MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 "HPA042334: AB_10794418" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (7.56e-3)" "unprognostic (1.30e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-2)" "prognostic favorable (1.75e-7)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" MIGA1 "FAM73A, FLJ35093" ENSG00000180488 "Mitoguardin 1" Q8NAN2 1 77779624-77879540 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017589 Approved Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Mitochondria "HPA017589: AB_1848409" "unprognostic (3.27e-1)" "unprognostic (1.19e-2)" "unprognostic (7.31e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (3.48e-2)" "unprognostic (2.70e-2)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (6.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.89e-1)" "unprognostic (1.68e-1)" "unprognostic (4.71e-2)" "unprognostic (4.75e-2)" MIGA2 "C9orf54, FAM73B, FLJ00199, FLJ14596" ENSG00000148343 "Mitoguardin 2" Q7L4E1 9 129036621-129072082 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041363 Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 57: Platelets - Hemostasis" Cytosol "Cell Junctions" "HPA041363: AB_10794664" "unprognostic (2.10e-1)" "unprognostic (4.82e-3)" "unprognostic (1.07e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (1.01e-1)" "unprognostic (3.93e-2)" "unprognostic (3.07e-3)" "unprognostic (2.90e-2)" "prognostic favorable (3.04e-6)" "unprognostic (1.12e-2)" "unprognostic (1.44e-3)" "unprognostic (8.57e-3)" "unprognostic (1.25e-1)" "unprognostic (4.63e-2)" "unprognostic (4.15e-3)" MILR1 "Allergin-1, C17orf60, MCA-32" ENSG00000271605 "Mast cell immunoglobulin like receptor 1" Q7Z6M3 17 64449037-64468643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in many" "dendritic cells: 64.7;Hofbauer cells: 76.0;Kupffer cells: 22.9;Macrophages: 26.5;Microglial cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 83.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 35.9" "Low region specificity" "Detected in all" HPA014347 Enhanced NA NA 50000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 58: Macrophages - Innate immune response" 4 "HPA014347: AB_2732408" "unprognostic (8.40e-2)" "unprognostic (9.77e-2)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (1.17e-1)" "unprognostic (1.21e-2)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.25e-1)" "unprognostic (3.31e-2)" "unprognostic (5.99e-3)" "unprognostic (4.78e-2)" "prognostic unfavorable (5.07e-6)" "unprognostic (2.51e-2)" "unprognostic (7.12e-3)" "unprognostic (1.09e-1)" "unprognostic (5.99e-2)" MINAR1 "KIAA1024, UBTOR" ENSG00000169330 "Membrane integral NOTCH2 associated receptor 1" Q9UPX6 15 79432336-79472304 "Predicted membrane proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;brain: 7.9;retina: 6.6" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 13.4;Muller glia cells: 22.9;Oligodendrocyte precursor cells: 6.1;Oligodendrocytes: 5.5;Oocytes: 10.3;Serous glandular cells: 5.8" "Cancer enhanced" "Detected in single" "melanoma: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011545 Uncertain Approved "Golgi apparatus" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 5 "Golgi apparatus" "HPA011545: AB_1852361" "unprognostic (5.45e-5)" "unprognostic (3.26e-1)" "unprognostic (4.56e-3)" "unprognostic (2.12e-2)" "unprognostic (1.74e-1)" "unprognostic (6.82e-2)" "unprognostic (4.49e-2)" "unprognostic (5.66e-2)" "unprognostic (2.90e-1)" "unprognostic (3.16e-1)" "unprognostic (1.96e-1)" "unprognostic (4.45e-2)" "unprognostic (6.66e-13)" "unprognostic (7.08e-2)" "unprognostic (2.73e-2)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" MINAR2 KIAA1024L ENSG00000186367 "Membrane integral NOTCH2 associated receptor 2" P59773 5 129748094-129766732 "Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 70 "skeletal muscle: 34.0" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA013760 Uncertain NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 69: Neurons - Neuronal signaling" "HPA013760: AB_1852363" "unprognostic (1.77e-1)" "unprognostic (5.13e-1)" MIP "AQP0, LIM1, MP26" ENSG00000135517 "Major intrinsic protein of lens fiber" P30301 12 56449502-56469166 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Transport, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014940 Supported NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" 35 "HPA014940: AB_2669122" "unprognostic (6.48e-2)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (7.14e-2)" "unprognostic (3.96e-2)" "unprognostic (2.90e-3)" "unprognostic (1.72e-1)" "unprognostic (3.47e-1)" "unprognostic (1.51e-5)" "unprognostic (4.56e-3)" "unprognostic (6.75e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-2)" "unprognostic (3.27e-1)" "unprognostic (2.62e-1)" "unprognostic (8.82e-2)" MKNK1 MNK1 ENSG00000079277 "MAPK interacting serine/threonine kinase 1" Q9BUB5 1 46557407-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 124.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 139.2;Microglial cells: 95.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 6 Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: AB_2686382" "unprognostic (4.05e-3)" "prognostic favorable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" MLANA "MART-1, MART1" ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 41.8" "Cell type enriched" "Detected in some" 49 "Melanocytes: 2387.8" "Cancer enriched" "Detected in single" 556 "melanoma: 277.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 57 "skin cancer: 399.2" "Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB000057, HPA048662" Enhanced NA NA "Cluster 82: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 3 "CAB000057: AB_442107, HPA048662: AB_2680485" "unprognostic (2.52e-2)" "unprognostic (6.87e-2)" "unprognostic (5.20e-2)" "unprognostic (5.61e-2)" "unprognostic (2.58e-2)" "unprognostic (1.46e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-3)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (8.01e-2)" "unprognostic (5.78e-2)" "unprognostic (9.43e-2)" MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 220.6" "Cell type enriched" "Detected in some" 4 "Astrocytes: 109.6" "Cancer enriched" "Detected in some" 69 "glioma: 122.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 65.7;Myeloma: 63.1" "Liver - NK-cells (Liver)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Astrocytes - Unknown function" 13 Cytosol "HPA003040: AB_1079387" "unprognostic (2.68e-2)" "unprognostic (5.46e-6)" "unprognostic (5.41e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (7.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-3)" "unprognostic (8.39e-4)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" MLLT10 AF10 ENSG00000078403 "MLLT10 histone lysine methyltransferase DOT1L cofactor" P55197 10 21524646-21743630 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 90.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 194.5;Inhibitory neurons: 162.6;Spermatocytes: 218.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005736, HPA005747, HPA072790" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 21: Testis - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 31: Spermatocytes - Spermatogenesis" 3 Nucleoplasm Cytosol "HPA005736: , HPA005747: AB_1079393, HPA072790: " "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (1.31e-2)" "prognostic favorable (8.75e-4)" "unprognostic (1.03e-3)" "unprognostic (9.56e-3)" "unprognostic (9.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.69e-2)" "unprognostic (7.85e-2)" "unprognostic (6.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 146.9;brain: 89.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 57: Platelets - Hemostasis" 16 Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.3;kidney: 292.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 76.6;Cytotrophoblasts: 78.8;Endometrial stromal cells: 269.5;Prostatic glandular cells: 119.5;Proximal enterocytes: 322.6;Syncytiotrophoblasts: 127.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Region enhanced" "Detected in all" "basal ganglia: 37.9" "Immune cell enriched" "Detected in some" 123 "neutrophil: 139.9" "Lineage enriched" "Detected in many" 123 "granulocytes: 139.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Fibroblasts, Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Region enhanced" "Detected in all" "basal ganglia: 43.8" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 74: Neutrophils - Degranulation" 3 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" MMGT1 "EMC5, TMEM32" ENSG00000169446 "Membrane magnesium transporter 1" Q8N4V1 X 135960588-135974029 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032037 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" 50 "HPA032037: AB_10670705" "prognostic unfavorable (8.54e-4)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.90e-2)" "unprognostic (2.23e-3)" "unprognostic (8.94e-3)" "unprognostic (2.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-1)" "unprognostic (3.87e-1)" "unprognostic (2.35e-1)" "unprognostic (2.38e-1)" "prognostic favorable (1.94e-5)" "unprognostic (6.08e-2)" "unprognostic (2.94e-2)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 260.9;Pancreatic endocrine cells: 120.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 126.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 17 Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 51.5;Distal enterocytes: 88.5;Extravillous trophoblasts: 53.6;Proximal enterocytes: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 2254.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.0" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 69.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 17.4;Excitatory neurons: 23.8;Horizontal cells: 15.1;Inhibitory neurons: 36.8;Mesothelial cells: 20.4;Oligodendrocyte precursor cells: 11.8;Oligodendrocytes: 11.2;Proximal tubular cells: 13.6" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 4 "cerebellum: 88.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.5;Kidney cancer: 41.0" "Adipose visceral - Mesothelial cells, Colon - Smooth muscle cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 68.1" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" Yes No "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" MOG "BTN6, BTNL11" ENSG00000204655 "Myelin oligodendrocyte glycoprotein" Q16653 6 29657002-29672372 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 253 "brain: 656.9" "Cell type enriched" "Detected in some" 49 "Oligodendrocytes: 439.6" "Cancer enriched" "Detected in single" 45 "glioma: 15.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Region enhanced" "Detected in all" "white matter: 1396.9" "Low region specificity" "Detected in all" HPA021873 Enhanced NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" "HPA021873: AB_1854055" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (3.00e-4)" "unprognostic (4.89e-2)" "unprognostic (4.90e-2)" MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Breast glandular cells: 7.4;Cholangiocytes: 9.5;Exocrine glandular cells: 4.0;Glandular and luminal cells: 4.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Breast glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 46.9;liver: 24.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 67.6;Hepatocytes: 67.9;Intestinal goblet cells: 32.2;Paneth cells: 21.3;Proximal enterocytes: 147.4;Undifferentiated cells: 19.7" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA028834 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" MOGAT3 "DC7, DGAT2L2, MGAT3" ENSG00000106384 "Monoacylglycerol O-acyltransferase 3" Q86VF5 7 101195007-101201038 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 23.7;liver: 18.4" "Group enriched" "Detected in some" 5 "Distal enterocytes: 87.1;Paneth cells: 41.0;Proximal enterocytes: 90.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 11.0;liver cancer: 11.1;stomach cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.6;liver cancer: 3.7" "Colon - Colon enterocytes" HPA011940 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA011940: AB_1854057" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (7.14e-2)" "unprognostic (6.11e-2)" "unprognostic (3.20e-1)" "unprognostic (9.54e-3)" "unprognostic (9.36e-2)" "unprognostic (3.08e-1)" "unprognostic (1.05e-3)" "unprognostic (1.87e-1)" "unprognostic (1.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.59e-2)" MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Endoplasmic reticulum" "HPA011322: AB_2668483, HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavorable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" MOSPD1 dJ473B4 ENSG00000101928 "Motile sperm domain containing 1" Q9UJG1 X 134887632-134915257 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 77.5;Early spermatids: 93.1;Late spermatids: 70.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 21.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031158 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoplasm, Vesicles" "HPA031158: AB_10603874" "unprognostic (2.23e-3)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.77e-1)" "unprognostic (3.36e-1)" "unprognostic (6.78e-3)" "unprognostic (5.15e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (6.20e-3)" "unprognostic (4.27e-2)" "unprognostic (6.45e-3)" "unprognostic (2.92e-2)" "unprognostic (2.01e-1)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" MOSPD2 MGC26706 ENSG00000130150 "Motile sperm domain containing 2" Q8NHP6 X 14873421-14922327 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 53.6" "Group enriched" "Detected in all" 6 "granulocytes: 53.6;monocytes: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003334 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" 6 "Endoplasmic reticulum" "HPA003334: AB_2146004" "unprognostic (2.74e-1)" "unprognostic (4.39e-2)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (7.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (8.91e-4)" "unprognostic (1.51e-1)" "unprognostic (7.24e-2)" "unprognostic (4.21e-3)" "unprognostic (1.00e-1)" "unprognostic (8.64e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.69e-1)" "unprognostic (1.96e-2)" MOSPD3 "CDS3, NET30" ENSG00000106330 "Motile sperm domain containing 3" O75425 7 100612102-100615384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 1447.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041137 Uncertain Approved Cytosol NA No "Cluster 9: T-regs - Cell cycle regulation" "Cluster 78: Testis - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 13 Cytosol "HPA041137: AB_10803996" "unprognostic (1.24e-1)" "unprognostic (8.98e-2)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.25e-2)" "unprognostic (1.80e-2)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (9.88e-2)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (8.65e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 62.2;smooth muscle: 75.8" "Cell type enhanced" "Detected in many" "Astrocytes: 87.9;Basal squamous epithelial cells: 79.6;Early spermatids: 90.8;Endometrial stromal cells: 53.0;Excitatory neurons: 34.9;Oligodendrocyte precursor cells: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cancer enhanced" "Detected in many" "skin cancer: 61.1" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035740 Approved Approved Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" 1 Cytosol "HPA035740: AB_10610141" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (8.05e-2)" "unprognostic (9.87e-3)" "unprognostic (5.62e-2)" "prognostic favorable (7.09e-5)" "unprognostic (5.77e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.92e-2)" "unprognostic (6.24e-2)" "unprognostic (1.73e-2)" MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 713.5;tongue: 536.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1264.2;Distal tubular cells: 1281.6;Proximal tubular cells: 517.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916675-167937072 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 2077.9;Late spermatids: 5323.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 14 "HPA056091: AB_2683035" "unprognostic (3.25e-1)" "unprognostic (6.82e-2)" "unprognostic (8.79e-3)" "unprognostic (4.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-3)" "unprognostic (1.44e-3)" "unprognostic (1.08e-2)" "unprognostic (9.13e-2)" "unprognostic (2.39e-1)" "unprognostic (6.95e-2)" "unprognostic (5.43e-2)" "unprognostic (1.67e-1)" MPDU1 "CDGIf, Lec35, PQLC5, SL15, SLC66A5" ENSG00000129255 "Mannose-P-dolichol utilization defect 1" O75352 17 7583529-7592789 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014845 Uncertain Supported "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "Endoplasmic reticulum" Mitochondria "HPA014845: AB_1854072" "unprognostic (1.96e-1)" "unprognostic (8.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.36e-2)" "unprognostic (5.00e-2)" "unprognostic (5.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (4.70e-2)" "unprognostic (3.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.34e-3)" "unprognostic (9.00e-2)" "unprognostic (2.60e-1)" "unprognostic (2.48e-3)" "unprognostic (2.93e-1)" MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 200.1" "Cell type enhanced" "Detected in some" "dendritic cells: 324.9;Hofbauer cells: 102.7;Kupffer cells: 424.4;Macrophages: 187.8;monocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 289.4;intermediate monocyte: 209.0;myeloid DC: 144.2;non-classical monocyte: 245.5;plasmacytoid DC: 204.5" "Group enriched" "Detected in many" 6 "dendritic cells: 204.5;monocytes: 289.4" "Group enriched" "Detected in some" 237 "Leukemia: 10.4;lymphoma: 36.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046801 Approved "Secreted to blood" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" MPG MDG ENSG00000103152 "N-methylpurine DNA glycosylase" P29372 16 77007-85851 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006531 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 Nucleoplasm Cytosol "HPA006531: AB_1854075" "unprognostic (1.78e-2)" "unprognostic (8.48e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.82e-5)" "unprognostic (8.54e-2)" "unprognostic (3.27e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-2)" "unprognostic (1.83e-2)" "unprognostic (1.39e-2)" "unprognostic (1.86e-3)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (3.26e-1)" MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130310-71150101 "Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 2 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: AB_2674436, HPA035060: AB_10601875, HPA049907: AB_2680947" "unprognostic (3.20e-3)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-3)" "unprognostic (6.13e-2)" "unprognostic (3.50e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (3.89e-7)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (2.47e-1)" "unprognostic (2.23e-2)" MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.7;skin 1: 8.0" "Cell type enhanced" "Detected in some" "dendritic cells: 11.9;Early spermatids: 4.6;Erythroid cells: 9.4;granulocytes: 23.5;Late spermatids: 11.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.6" "Adipose subcutaneous - Mast cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 330000 "Cluster 13: Skin - Cornification" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Erythroid cells: 2.2;Ovarian stromal cells: 3.1;Rod photoreceptor cells: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cancer enriched" "Detected in single" 9 "Leukemia: 5.9" "Testis - Early spermatids" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" MPPE1 "Cdc1, PGAP5" ENSG00000154889 "Metallophosphoesterase 1" Q53F39 18 11882622-11908366 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, GPI-anchor biosynthesis, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 101.8;neutrophil: 297.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 297.3" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012639 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 19: NK-cells - Adaptive immune response" 1 "Nucleoplasm, Golgi apparatus" "HPA012639: AB_1854088" "unprognostic (9.23e-2)" "unprognostic (1.54e-1)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.00e-2)" "unprognostic (4.46e-1)" "unprognostic (1.61e-1)" "prognostic favorable (6.45e-7)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" "unprognostic (6.15e-2)" MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 13.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 35.9;Melanocytes: 27.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" MPV17L2 "FKSG24, MGC12972" ENSG00000254858 "MPV17 mitochondrial inner membrane protein like 2" Q567V2 19 18193218-18196948 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043111 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 14: Langerhans cells - Innate immune response" "HPA043111: AB_10794176" "unprognostic (3.71e-1)" "unprognostic (2.75e-3)" "unprognostic (5.52e-2)" "unprognostic (1.28e-1)" "unprognostic (6.74e-2)" "unprognostic (8.23e-2)" "unprognostic (4.41e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (9.93e-3)" "unprognostic (5.21e-2)" "unprognostic (1.99e-1)" "prognostic favorable (2.30e-4)" "unprognostic (1.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (5.20e-2)" MPZ "CMT1, CMT1B, CMT2I, CMT2J, HMSNIB, P0" ENSG00000158887 "Myelin protein zero" P25189 1 161304735-161309968 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.2" "Cell type enriched" "Detected in many" 16 "Schwann cells: 552.7" "Cancer enriched" "Detected in many" 11 "melanoma: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 17.5;skin cancer: 61.4" "Colon - Enteric glia cells, Liver - Vascular Endothelial cells" "Group enriched" "Detected in some" 4 "olfactory bulb: 2.9;pons and medulla: 1.3" "Region enriched" "Detected in many" 10 "spinal cord: 2820.7" HPA068925 Enhanced NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA068925: AB_2732123" "unprognostic (6.77e-2)" "unprognostic (2.98e-1)" "unprognostic (9.27e-2)" "unprognostic (1.46e-1)" "unprognostic (3.35e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-2)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "unprognostic (7.88e-3)" "unprognostic (1.51e-1)" "unprognostic (6.62e-8)" "unprognostic (6.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (8.32e-2)" MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 184.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 184.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Fibroblasts - ECM organization" 1 "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.2;urinary bladder: 150.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 291.2;Basal respiratory cells: 265.4;Glandular and luminal cells: 180.1;Squamous epithelial cells: 367.3;Suprabasal keratinocytes: 440.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.7" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "spinal cord: 51.3" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.4;skin 1: 29.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 32.6;Glandular and luminal cells: 34.4;Suprabasal keratinocytes: 41.2;T-cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 44.4;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Golgi apparatus" "HPA029116: AB_10610142" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (8.74e-3)" "unprognostic (2.86e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (4.86e-2)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.90e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.20e-1)" MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033374-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" MRAP "B27, C21orf61, FALP" ENSG00000170262 "Melanocortin 2 receptor accessory protein" Q8TCY5 21 32291813-32314784 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "adipose tissue: 73.2;adrenal gland: 161.2;breast: 42.8" "Group enriched" "Detected in some" 6 "Early spermatids: 21.0;Horizontal cells: 12.0;Late spermatids: 5.9;Sertoli cells: 8.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011024, HPA011093" Uncertain Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 50: Connective tissue cells - ECM organization" 3 "Endoplasmic reticulum" Vesicles "HPA011024: AB_10599292, HPA011093: AB_10600889" "unprognostic (1.38e-1)" "unprognostic (1.55e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (9.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.80e-2)" "unprognostic (4.12e-1)" "unprognostic (6.30e-6)" "unprognostic (3.32e-2)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.76e-2)" MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 118.5" "Group enriched" "Detected in many" 4 "Breast glandular cells: 124.7;Hofbauer cells: 157.9;Kupffer cells: 348.2;Langerhans cells: 206.5;Lymphatic endothelial cells: 244.1;Macrophages: 414.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 20.4" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 8.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 62.5;Fibroblasts: 122.9;Late spermatids: 90.3;Leydig cells: 71.9;Peritubular cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 132.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" MRGPRD mrgD ENSG00000172938 "MAS related GPR family member D" Q8TDS7 11 68980021-68980986 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031346 Uncertain NA NA "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "HPA031346: AB_10602710" "unprognostic (1.92e-1)" "unprognostic (7.14e-2)" "unprognostic (1.72e-1)" MRGPRE "GPR167, mrgE" ENSG00000184350 "MAS related GPR family member E" Q86SM8 11 3225030-3232417 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Erythroid cells: 1.1;Horizontal cells: 2.5" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.9" "Region enhanced" "Detected in many" "pons: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046556 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA046556: AB_10961404" "unprognostic (1.18e-1)" "unprognostic (7.52e-4)" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (6.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 165.4;intestine: 153.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 30.0;Leydig cells: 66.2;Mesothelial cells: 31.1;Ovarian stromal cells: 29.9;Peritubular cells: 97.6;Smooth muscle cells: 96.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.4" "Breast - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in many" "spinal cord: 6.4" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" MRGPRG "GPR169, mrgG" ENSG00000182170 "MAS related GPR family member G" Q86SM5 11 3217944-3218813 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "breast cancer: 2.1" "Not detected" "Not detected" HPA058909 Uncertain NA NA "Cluster 70: DU4475 - Unknown function" "HPA058909: AB_2683852" MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Group enriched" "Detected in some" 5 "granulocytes: 6.7;Melanocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Skin - Mast cells" HPA055220 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Granulocytes - Unknown function" "HPA055220: AB_2682743" "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139360497 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006083: AB_1854122, HPA007830: AB_1854123" "unprognostic (8.38e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (5.22e-3)" "unprognostic (5.45e-3)" "unprognostic (4.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" "unprognostic (4.49e-3)" "prognostic unfavorable (1.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.22e-3)" "unprognostic (2.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.77e-1)" "unprognostic (3.40e-1)" MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA017642: AB_2669628" "unprognostic (2.12e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-3)" "prognostic unfavorable (5.32e-4)" "unprognostic (7.23e-2)" "unprognostic (8.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-3)" "prognostic favorable (5.14e-11)" "unprognostic (8.75e-2)" "unprognostic (2.94e-2)" "unprognostic (8.32e-2)" "unprognostic (2.53e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.55e-3)" MS4A1 "B1, Bp35, CD20, FMC7" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 655.0" "Cell type enriched" "Detected in some" 55 "B-cells: 969.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 627.9;naive B-cell: 630.0" "Lineage enriched" "Detected in many" 96 "B-cells: 630.0" "Cancer enriched" "Detected in some" 6 "lymphoma: 397.8" "Breast - T-cells, Lung - B-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 27 "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" MS4A10 "CD20L7, MS4A9" ENSG00000172689 "Membrane spanning 4-domains A10" Q96PG2 11 60785333-60801305 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 96 "intestine: 83.3" "Cell type enriched" "Detected in some" 39 "Proximal enterocytes: 309.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014778 Uncertain NA NA "Cluster 25: Small intestine - Absorption" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA014778: AB_2669089" "unprognostic (7.67e-3)" "unprognostic (1.28e-1)" "unprognostic (8.73e-3)" "unprognostic (1.27e-1)" "unprognostic (5.21e-2)" MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 246.1" "Cell type enriched" "Detected in some" 15 "Distal enterocytes: 928.6" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" MS4A13 ENSG00000204979 "Membrane spanning 4-domains A13" Q5J8X5 11 60515392-60542721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "testis: 3.4" "Cell type enhanced" "Detected in some" "Early spermatids: 26.7;Late spermatids: 48.6;Spermatocytes: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045017, HPA063626" Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" 52 "HPA045017: AB_10962976, HPA063626: AB_2685065" MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 71.0" "Group enriched" "Detected in some" 17 "Early spermatids: 255.1;Late spermatids: 670.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" 5 Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.78e-1)" "unprognostic (1.76e-1)" "unprognostic (5.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (4.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (2.14e-1)" "unprognostic (4.50e-6)" "unprognostic (3.73e-2)" "unprognostic (7.16e-3)" "unprognostic (8.40e-2)" "unprognostic (7.11e-2)" MS4A15 ENSG00000166961 "Membrane spanning 4-domains A15" Q8N5U1 11 60756867-60776733 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "lung: 42.5" "Cell type enriched" "Detected in some" 6 "Alveolar cells type 1: 23.1" "Cancer enhanced" "Detected in many" "lung cancer: 6.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Lineage enriched" "Detected in single" 12 "T-cells: 3.2" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.1;lung cancer: 2.8;Myeloma: 2.9" "Lung - Alveolar cells type 1" "Region enriched" "Detected in some" 28 "olfactory bulb: 166.8" "Region enriched" "Detected in some" 27 "olfactory bulb: 27.3" HPA054563 Approved "Plasma membrane,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 57: Lung - Lung function" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane" Cytosol "HPA054563: " "unprognostic (1.85e-1)" "unprognostic (4.31e-3)" "unprognostic (8.59e-2)" "unprognostic (5.89e-4)" "unprognostic (4.49e-1)" "unprognostic (1.09e-3)" "unprognostic (3.92e-3)" "unprognostic (5.43e-3)" "unprognostic (1.20e-1)" "unprognostic (7.30e-2)" "unprognostic (3.14e-1)" "unprognostic (1.04e-9)" "unprognostic (7.02e-2)" "unprognostic (8.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-1)" MS4A18 ENSG00000214782 "Membrane spanning 4-domains A18" Q3C1V0 11 60724720-60745028 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 19 "breast: 5.8;intestine: 18.1" "Group enriched" "Detected in some" 5 "Early spermatids: 5.0;Late spermatids: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045121 Approved NA NA "Cluster 25: Small intestine - Absorption" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 11: Late spermatids - Unknown function" "HPA045121: AB_10969456" "unprognostic (1.02e-1)" "unprognostic (8.87e-2)" "unprognostic (2.51e-1)" MS4A2 "APY, FCER1B, IGER" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.2" "Cell type enriched" "Detected in some" 29 "granulocytes: 1187.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 873 "basophil: 275.8" "Lineage enriched" "Detected in single" 1528 "granulocytes: 275.8" "Cancer enriched" "Detected in single" 14 "Leukemia: 1.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Kidney - T-cells, Lung - Mast cells, Skin - Mast cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 20.9" HPA059967 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" 1 "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" MS4A3 "CD20L, HTM4" ENSG00000149516 "Membrane spanning 4-domains A3" Q96HJ5 11 60056587-60071115 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 94 "bone marrow: 415.6" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 15.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 1476 "basophil: 2692.2" "Lineage enriched" "Detected in single" 4500 "granulocytes: 2692.2" "Cancer enriched" "Detected in single" 680 "Leukemia: 67.9" "Lung - Neutrophil_1" "Not detected" "Not detected" HPA019210 Supported Approved "Golgi apparatus" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 34 "Golgi apparatus" "HPA019210: AB_1854134" "unprognostic (6.37e-3)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.77e-1)" MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 61.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 362.5;Kupffer cells: 426.5;Macrophages: 256.0;monocytes: 185.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 83.2;plasmacytoid DC: 27.8" "Group enriched" "Detected in many" 30 "dendritic cells: 27.8;monocytes: 83.2" "Cancer enhanced" "Detected in some" "Leukemia: 11.2;Myeloma: 11.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" HPA029323 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 12 "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "granulocytes: 17.3;Kupffer cells: 7.8;Macrophages: 16.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.9" "Lineage enriched" "Detected in many" 8 "granulocytes: 17.9" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" HPA040075 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 40: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" MS4A5 CD20L2 ENSG00000166930 "Membrane spanning 4-domains A5" Q9H3V2 11 60429572-60455214 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 167 "testis: 43.3" "Group enriched" "Detected in some" 77 "Early spermatids: 644.0;Late spermatids: 1029.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA043732 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 11: Late spermatids - Unknown function" "HPA043732: AB_10959759" MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172015-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "dendritic cells: 421.7;Hofbauer cells: 524.2;Kupffer cells: 1337.8;Langerhans cells: 548.3;Macrophages: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 524.7;classical monocyte: 1399.3;intermediate monocyte: 459.3;myeloid DC: 813.7;plasmacytoid DC: 558.7" "Group enriched" "Detected in all" 70 "dendritic cells: 813.7;granulocytes: 524.7;monocytes: 1399.3" "Cancer enriched" "Detected in some" 8 "Leukemia: 21.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" MS4A6E ENSG00000166926 "Membrane spanning 4-domains A6E" Q96DS6 11 60327255-60396596 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 19.9" "Group enriched" "Detected in some" 103 "Early spermatids: 1091.4;Late spermatids: 391.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids" HPA076623 Approved Vesicles NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 21: Early spermatids - Spermatogenesis" 2 Vesicles "HPA076623: AB_2686809" "unprognostic (2.58e-1)" "unprognostic (3.35e-1)" "unprognostic (3.47e-1)" "unprognostic (6.81e-3)" "unprognostic (4.55e-4)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 191.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 367.8;Kupffer cells: 814.3;Macrophages: 564.7;monocytes: 1574.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 749.2;non-classical monocyte: 1495.7" "Lineage enriched" "Detected in many" 12 "monocytes: 1495.7" "Group enriched" "Detected in some" 5 "breast cancer: 2.3;Leukemia: 7.7;lymphoma: 3.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 7 "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" MS4A8 "CD20L5, MS4A4, MS4A8B" ENSG00000166959 "Membrane spanning 4-domains A8" Q9BY19 11 60699585-60715807 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 125.4;intestine: 192.2" "Group enriched" "Detected in some" 8 "Ciliated cells: 294.7;Enteroendocrine cells: 323.1;Proximal enterocytes: 686.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Region enhanced" "Detected in many" "choroid plexus: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "lung cancer: 11.2" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007319 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "HPA007319: AB_1854138" "unprognostic (7.28e-3)" "unprognostic (2.11e-1)" "unprognostic (9.03e-2)" "unprognostic (1.91e-2)" "unprognostic (2.52e-2)" "unprognostic (9.41e-2)" "unprognostic (4.89e-3)" "unprognostic (9.33e-2)" "unprognostic (7.97e-3)" "unprognostic (2.40e-1)" "unprognostic (2.40e-9)" "unprognostic (2.46e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-3)" MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.4;fallopian tube: 268.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 344.4;Ionocytes: 378.5;Mesothelial cells: 758.3;Paneth cells: 198.8;Secretory cells: 822.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 100.1;pancreatic cancer: 97.1" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 3.8" "CAB002216, HPA017172, CAB080356, CAB080357" Enhanced Supported "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 17000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 59: Fallopian tube - Tissue development" "Cluster 18: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Plasma membrane" "CAB002216: AB_563874, CAB080356: , CAB080357: , HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9036.6" "Cell type enriched" "Detected in many" 11 "Prostatic glandular cells: 29753.7" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "prostate cancer: 295.9" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 6000000 "Cluster 64: Neuronal - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 558.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 436.0;Hepatocytes: 466.8;Suprabasal keratinocytes: 235.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 14 "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 116.4" "Group enriched" "Detected in many" 6 "Hofbauer cells: 122.6;Kupffer cells: 261.4;Langerhans cells: 97.4;Macrophages: 191.1;monocytes: 231.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.8" "Lineage enriched" "Detected in many" 5 "monocytes: 16.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" 7 "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8;skin 1: 31.1;stomach 1: 26.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.7;Distal enterocytes: 32.8;Gastric mucus-secreting cells: 92.0;Intestinal goblet cells: 25.9;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 49.5" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Gastric mucus-secreting cells - Digestion" 3 Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 247736.1;tongue: 177371.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 66649.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 204529.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 77862.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 5 "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" MT-CO3 "CO3, COIII, COX3, MTCO3" ENSG00000198938 "Mitochondrially encoded cytochrome c oxidase III" P00414 MT 9207-9990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 224217.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 83612.3;Horizontal cells: 58765.3;Rod photoreceptor cells: 56654.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042788 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "HPA042788: AB_10793985" "unprognostic (2.38e-1)" "unprognostic (5.24e-2)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (3.04e-1)" "unprognostic (2.93e-1)" "prognostic favorable (2.01e-4)" "unprognostic (1.18e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-2)" "prognostic favorable (1.04e-4)" "unprognostic (1.05e-1)" "unprognostic (8.80e-3)" "unprognostic (2.75e-2)" "unprognostic (1.20e-1)" "unprognostic (9.29e-2)" "unprognostic (1.33e-2)" MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 126391.2" "Cell type enhanced" "Detected in all" "Bipolar cells: 60700.4;Cardiomyocytes: 59557.2;Cone photoreceptor cells: 33405.1;Rod photoreceptor cells: 37944.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "CAB032215: AB_2261378, HPA068400: AB_2685982, HPA074796: " "unprognostic (4.50e-1)" "unprognostic (2.56e-1)" "unprognostic (9.12e-2)" "unprognostic (3.88e-2)" "unprognostic (9.22e-2)" "unprognostic (3.50e-1)" "prognostic favorable (5.96e-4)" "unprognostic (1.63e-2)" "unprognostic (8.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.40e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.54e-2)" MT-ND1 "MTND1, NAD1, ND1" ENSG00000198888 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1" P03886 MT 3307-4262 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Diabetes mellitus, Disease variant, Epilepsy, FDA approved drug targets, Leber hereditary optic neuropathy, MELAS syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 124124.2" "Cell type enhanced" "Detected in all" "Bipolar cells: 21652.6;Cardiomyocytes: 30374.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9528.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 9528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033779, HPA066847" Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "CAB033779: AB_2149736, HPA066847: " "prognostic favorable (3.63e-4)" "unprognostic (3.55e-1)" "unprognostic (3.77e-2)" "unprognostic (3.65e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.95e-3)" "unprognostic (5.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.26e-4)" "unprognostic (8.67e-2)" "unprognostic (8.66e-2)" "unprognostic (3.24e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.85e-2)" MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 178667.2" "Cell type enhanced" "Detected in all" "Bipolar cells: 23541.6;Cardiomyocytes: 24404.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Uncertain Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" Cytosol "HPA063296: AB_2684978" "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (8.10e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "prognostic favorable (4.63e-5)" "unprognostic (2.45e-2)" "unprognostic (7.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-3)" "unprognostic (1.74e-1)" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-1)" "unprognostic (5.65e-3)" MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 190669.7" "Cell type enhanced" "Detected in all" "Bipolar cells: 57626.6;Cardiomyocytes: 105258.3;Rod photoreceptor cells: 46287.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13564.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved Supported Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "HPA053928: AB_2682313" "unprognostic (8.39e-2)" "unprognostic (1.83e-1)" "unprognostic (7.29e-2)" "unprognostic (9.54e-2)" "unprognostic (5.41e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-3)" "unprognostic (8.16e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.01e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (3.14e-2)" "unprognostic (4.24e-2)" MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140746.3;tongue: 98837.0" "Cell type enriched" "Detected in all" 5 "Cardiomyocytes: 26934.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Centrosome,Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "Centrosome, Cytosol" "HPA075648: AB_2686760" "unprognostic (5.81e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-2)" "unprognostic (7.91e-2)" "unprognostic (5.64e-2)" "unprognostic (1.05e-1)" "prognostic favorable (4.47e-4)" "unprognostic (1.97e-1)" "unprognostic (4.04e-2)" "unprognostic (4.63e-3)" "unprognostic (6.61e-2)" "unprognostic (7.38e-3)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (3.73e-1)" "unprognostic (2.97e-2)" "unprognostic (5.68e-2)" MTARC2 "FLJ20605, MARC2, MOSC2" ENSG00000117791 "Mitochondrial amidoxime reducing component 2" Q969Z3 1 220748225-220784815 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 127.2;liver: 216.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.5;Proximal enterocytes: 61.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.9" "Region enriched" "Detected in all" 5 "choroid plexus: 109.4" "Immune cell enriched" "Detected in some" 6 "basophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015085, HPA017572" Enhanced NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA015085: AB_1848780, HPA017572: AB_1848778" "unprognostic (8.17e-2)" "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.40e-10)" "unprognostic (4.78e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (6.23e-2)" MTCH1 "CGI-64, PSAP, SLC25A49" ENSG00000137409 "Mitochondrial carrier 1" Q9NZJ7 6 36965807-36986298 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015971 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA015971: AB_1854171" "unprognostic (3.17e-2)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.29e-1)" "unprognostic (2.88e-2)" "unprognostic (1.54e-1)" "unprognostic (7.49e-2)" "unprognostic (1.35e-3)" "prognostic favorable (1.16e-7)" "unprognostic (1.32e-2)" "unprognostic (3.11e-1)" "unprognostic (6.68e-2)" "unprognostic (4.70e-2)" MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 593.2;Proximal tubular cells: 453.6;Spermatocytes: 397.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 1 Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" MTDH "3D3, AEG-1, LYRIC" ENSG00000147649 Metadherin Q86UE4 8 97644184-97730260 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA010932, HPA015104, CAB068204, CAB068205" Supported Enhanced "Endoplasmic reticulum" NA NA 300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "CAB068204: AB_2665655, CAB068205: AB_2665654, HPA010932: AB_1079422, HPA015104: AB_1854173" "unprognostic (1.01e-3)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.25e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.84e-3)" "unprognostic (3.88e-2)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 67.6;Exocrine glandular cells: 49.0;Pancreatic endocrine cells: 45.8;Undifferentiated cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: T-cells - T-cell receptor" 1 Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 16.1;testis: 6.8" "Cell type enriched" "Detected in many" 5 "Oocytes: 148.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 28: Non-specific - Nuclear processes" "Cluster 44: Oocytes - Unknown function" 6 Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 81.2;Extravillous trophoblasts: 185.0;Microglial cells: 120.8;Syncytiotrophoblasts: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 13: Non-specific - Mitochondria" "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 4: Extravillous trophoblasts - Unknown function" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969651-92985066 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "placenta: 1.0" "Cell type enhanced" "Detected in single" "Granulosa cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8;testis cancer: 1.2" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074024 Supported NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 4 "HPA074024: " "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17801094 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 398.2;Oligodendrocytes: 436.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Non-specific - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nucleoli, Microtubules" "HPA067903: AB_2685921, HPA069795: AB_2686198" "unprognostic (3.20e-1)" "unprognostic (3.29e-1)" "prognostic favorable (1.05e-4)" "unprognostic (2.50e-2)" "unprognostic (2.27e-1)" "unprognostic (7.72e-3)" "unprognostic (1.36e-1)" "unprognostic (1.86e-3)" "unprognostic (2.44e-1)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (3.33e-1)" "prognostic favorable (2.76e-4)" "unprognostic (2.04e-1)" "unprognostic (2.38e-2)" "unprognostic (2.53e-3)" "unprognostic (2.43e-1)" MTX1 "MTX, MTXN" ENSG00000173171 "Metaxin 1" Q13505 1 155208695-155213824 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 254.6;Late spermatids: 911.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011543 Uncertain Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Testis - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" Mitochondria "HPA011543: AB_1853824" "unprognostic (2.57e-1)" "unprognostic (9.51e-3)" "unprognostic (3.27e-1)" "unprognostic (5.98e-3)" "unprognostic (1.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.28e-2)" "unprognostic (1.71e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-2)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 419.1;stomach 1: 862.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 963.7;Alveolar cells type 2: 1456.7;Exocrine glandular cells: 951.7;Gastric mucus-secreting cells: 572.5;Ionocytes: 447.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MUC12 MUC11 ENSG00000205277 "Mucin 12, cell surface associated" Q9UKN1 7 100969565-101018939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 65.6" "Cell type enriched" "Detected in many" 4 "Distal enterocytes: 728.6" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 13.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 56 "colorectal cancer: 8.7" "Colon - Colon enterocytes, Testis - Late spermatids" HPA023835 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA023835: AB_1854199" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (2.80e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-4)" "unprognostic (4.40e-2)" "unprognostic (1.30e-3)" "unprognostic (1.84e-2)" "unprognostic (1.40e-1)" "unprognostic (6.52e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (3.33e-7)" "unprognostic (8.42e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 597.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 500.9;Enteroendocrine cells: 161.4;Intestinal goblet cells: 447.1;Paneth cells: 323.4;Proximal enterocytes: 400.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 178.0;Gastric cancer: 65.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1903.7" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 952.8" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in all" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 3 "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" MUC16 "CA-125, CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.0;cervix: 15.4;fallopian tube: 5.7;salivary gland: 5.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 157.5;Club cells: 88.3;Glandular and luminal cells: 170.2;Ionocytes: 224.9;Mesothelial cells: 429.4;Salivary duct cells: 117.9" "Cancer enriched" "Detected in many" 4 "ovarian cancer: 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.7" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "CAB055172, HPA065600, CAB080360" Enhanced "Secreted in other tissues" "No annotated function" NA NA 25000 "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB055172: AB_2148831, CAB080360: , HPA065600: AB_2732736" "unprognostic (8.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.37e-2)" "unprognostic (3.07e-1)" "unprognostic (1.76e-2)" "unprognostic (3.01e-3)" "unprognostic (3.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (2.60e-8)" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "unprognostic (3.68e-3)" MUC17 ENSG00000169876 "Mucin 17, cell surface associated" Q685J3 7 101020072-101058859 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "intestine: 41.5" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 309.8" "Cancer enhanced" "Detected in some" "stomach cancer: 22.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 5.7;Gastric cancer: 10.4;pancreatic cancer: 4.1" "Colon - Colon enterocytes" "Not detected" "Not detected" HPA031634 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA031634: AB_10603021" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "unprognostic (8.17e-3)" "unprognostic (5.57e-3)" "unprognostic (6.07e-2)" "unprognostic (8.79e-8)" "unprognostic (1.28e-1)" "unprognostic (2.47e-2)" MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 132.1;esophagus: 676.9;vagina: 237.1" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 520.2" "Group enriched" "Detected in many" 9 "cervical cancer: 6.8;head and neck cancer: 6.6;lung cancer: 13.9;stomach cancer: 7.0;thyroid cancer: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "lung cancer: 2.5" "Lung - Alveolar cells type 2" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA052028: AB_2681700" "unprognostic (2.27e-2)" "unprognostic (4.85e-3)" "unprognostic (5.24e-3)" "unprognostic (1.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.98e-3)" "unprognostic (1.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.4;intestine: 40.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 179.2;Intestinal goblet cells: 179.0;Paneth cells: 140.9;Proximal enterocytes: 383.1;Undifferentiated cells: 115.8" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 8.3;Gastric cancer: 3.8" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" MUC4 ENSG00000145113 "Mucin 4, cell surface associated" Q99102 3 195746765-195811973 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.6;intestine: 30.3;prostate: 14.4;vagina: 14.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 85.3;Ciliated cells: 204.0;Club cells: 215.4;Distal enterocytes: 188.3;Gastric mucus-secreting cells: 144.4;Intestinal goblet cells: 131.1;Ionocytes: 305.6;Salivary duct cells: 110.2" "Cancer enhanced" "Detected in many" "cervical cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 3.4;head and neck cancer: 4.1;pancreatic cancer: 3.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "basal ganglia: 5.4" "HPA005895, CAB013536" Approved "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB013536: , HPA005895: AB_1079427" "unprognostic (4.16e-3)" "unprognostic (1.00e-2)" "unprognostic (6.79e-2)" "unprognostic (1.11e-2)" "unprognostic (3.03e-2)" "unprognostic (5.16e-2)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (3.19e-1)" "unprognostic (4.22e-3)" "unprognostic (6.68e-3)" "unprognostic (5.30e-2)" "unprognostic (2.43e-3)" "unprognostic (3.19e-1)" "unprognostic (6.78e-2)" "unprognostic (3.46e-3)" "unprognostic (9.97e-3)" MUCL3 "bCX105N19.6, C6orf37, DPCR1, PBLT" ENSG00000168631 "Mucin like 3" Q3MIW9 6 30934523-30954221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "stomach 1: 197.9" "Cell type enriched" "Detected in some" 9 "Gastric mucus-secreting cells: 973.4" "Group enriched" "Detected in some" 9 "pancreatic cancer: 56.8;stomach cancer: 55.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 11.8;pancreatic cancer: 6.6" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA014036 Enhanced NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA014036: AB_1847841" "unprognostic (2.81e-1)" "unprognostic (4.49e-2)" "unprognostic (9.13e-4)" "unprognostic (6.74e-2)" "unprognostic (4.29e-2)" "unprognostic (8.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.79e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (4.76e-2)" "unprognostic (9.80e-2)" "unprognostic (3.20e-2)" "unprognostic (3.58e-2)" MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508151 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 4 "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favorable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 13: Non-specific - Mitochondria" "Cluster 80: Non-specific - Endocytosis" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 62: Hepatocytes - Metabolism" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 148.3;Extravillous trophoblasts: 292.8;Fibroblasts: 193.9;Leydig cells: 166.1;Ovarian stromal cells: 124.2;Peritubular cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 574.0;Lymphatic endothelial cells: 459.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 208.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 9 "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" MYADML2 LOC255275 ENSG00000185105 "Myeloid associated differentiation marker like 2" A6NDP7 17 81939645-81947233 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 81.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.0;Early spermatids: 1.8;Horizontal cells: 5.7;Inhibitory neurons: 2.3;Skeletal myocytes: 13.7" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "lymphoma: 8.0" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041856, HPA048476" Uncertain NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 2: Skeletal myocytes - Muscle contraction" 10 "HPA041856: AB_2677709, HPA048476: AB_2680410" "unprognostic (1.83e-1)" "unprognostic (1.71e-2)" "unprognostic (7.07e-2)" "unprognostic (2.90e-4)" "unprognostic (2.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.32e-1)" "unprognostic (6.09e-2)" "unprognostic (1.44e-2)" "unprognostic (3.37e-2)" "unprognostic (4.16e-7)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (8.68e-2)" MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 246.4;skin 1: 280.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 601.9;Basal squamous epithelial cells: 992.6;Squamous epithelial cells: 677.0;Suprabasal keratinocytes: 633.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 88 Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697897-152724569 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.3" "Group enriched" "Detected in some" 4 "Adipocytes: 116.9;Endothelial cells: 129.5;Lymphatic endothelial cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 246 "granulocytes: 30.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;thyroid cancer: 5.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 120000 "Cluster 22: Eosinophils - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Nucleoplasm "Nuclear bodies, Vesicles" "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143024 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 78.9;monocytes: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Monocytes - Innate immune response" 20 Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69341682 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.2;breast: 5.0;esophagus: 9.3;stomach 1: 5.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.0;Breast myoepithelial cells: 31.7;Club cells: 12.0;Ductal cells: 10.6;Early spermatids: 11.4;Gastric mucus-secreting cells: 20.6;Paneth cells: 19.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" MYLK "KRP, MLCK, MLCK1, MLCK108, MLCK210, MYLK-L, MYLK1, smMLCK, Telokin" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1613.5;smooth muscle: 1992.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 906.1;Peritubular cells: 703.3;Sertoli cells: 220.3;Smooth muscle cells: 687.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Brain cancer: 92.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "heart muscle: 99.7;skeletal muscle: 44.8;tongue: 69.7" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 222.5;Skeletal myocytes: 83.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 5.4;testis cancer: 3.2" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.6" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 68: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2770330 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 27.8;tongue: 68.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.5;Inhibitory neurons: 6.9;Microglial cells: 4.5;Oligodendrocyte precursor cells: 7.5;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 1 "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" MYMK "MYOMAKER, TMEM226, TMEM8C" ENSG00000187616 "Myomaker, myoblast fusion factor" A6NI61 9 133514586-133528612 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 43 "Sarcoma: 7.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA051846, HPA055785" Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" "HPA051846: AB_2681636, HPA055785: AB_2682920" "unprognostic (9.17e-3)" "unprognostic (8.63e-2)" "unprognostic (3.76e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (5.37e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-1)" MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307281-52529132 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.2;parathyroid gland: 37.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 341.0;Inhibitory neurons: 231.0;Melanocytes: 144.3;Oligodendrocyte precursor cells: 310.4;Oligodendrocytes: 376.2" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 61.5" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 34: Neurons - Neuronal signaling" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Glandular and luminal cells: 129.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 78.3" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 190000 "Cluster 40: Monocytes - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "Plasma membrane, Centriolar satellite" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.1" "Cell type enhanced" "Detected in many" "Astrocytes: 39.0;Cholangiocytes: 26.7;Cytotrophoblasts: 55.3;Distal enterocytes: 47.9;Hepatocytes: 45.9;Paneth cells: 28.7;Proximal enterocytes: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" MYRF "C11orf9, MRF, Ndt80, pqn-47" ENSG00000124920 "Myelin regulatory factor" Q9Y2G1 11 61752636-61788518 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 160.2;stomach 1: 85.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 78.8;Cholangiocytes: 51.5;Gastric mucus-secreting cells: 118.5;Mesothelial cells: 68.3;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 52.9" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018310 Approved Nucleoplasm,Cytosol NA NA 1400000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA018310: AB_1845534" "unprognostic (3.51e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (5.39e-2)" "unprognostic (1.54e-1)" "unprognostic (3.65e-2)" "unprognostic (1.34e-1)" "unprognostic (9.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.91e-3)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" MYRFL "bcm1377, C12orf15, C12orf28, FLJ25056" ENSG00000166268 "Myelin regulatory factor like" Q96LU7 12 69825227-69959097 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 22.3" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 98.3;Late spermatids: 30.4;Oligodendrocyte precursor cells: 66.0;Proximal enterocytes: 32.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049340 Approved Approved Nucleoli "Intracellular and membrane" Other NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" Nucleoli "HPA049340: AB_2680719" "unprognostic (2.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.18e-2)" "unprognostic (2.34e-1)" "unprognostic (5.45e-2)" "unprognostic (6.50e-2)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (3.08e-1)" "unprognostic (8.99e-2)" "unprognostic (1.91e-2)" "unprognostic (3.89e-2)" "unprognostic (2.07e-2)" "unprognostic (1.17e-1)" "unprognostic (9.96e-2)" N4BP2L2 "CG005, PFAAP5" ENSG00000244754 "NEDD4 binding protein 2 like 2" Q92802 13 32432417-32538885 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039338, HPA039434, HPA059327" Approved Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 4 Nucleoplasm "HPA039338: AB_2676453, HPA039434: AB_10673143, HPA059327: AB_2683981" "unprognostic (1.13e-1)" "unprognostic (1.72e-1)" "unprognostic (3.15e-1)" "unprognostic (5.81e-2)" "unprognostic (6.83e-2)" "unprognostic (6.51e-2)" "unprognostic (8.95e-2)" "unprognostic (6.29e-3)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (2.71e-3)" "unprognostic (2.67e-2)" "unprognostic (4.73e-3)" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (4.03e-3)" NAA25 "C12orf30, FLJ13089" ENSG00000111300 "N-alpha-acetyltransferase 25, NatB auxiliary subunit" Q14CX7 12 112026689-112108796 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039322 Approved Supported "Golgi apparatus,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 3: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 14: Langerhans cells - Innate immune response" 1 "Golgi apparatus, Cytosol" "HPA039322: AB_10697548" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (3.91e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (9.09e-3)" "unprognostic (3.24e-2)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (8.34e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.44e-2)" "unprognostic (2.01e-1)" "unprognostic (9.34e-2)" "unprognostic (9.18e-2)" NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.6;Inhibitory neurons: 105.6;Oligodendrocyte precursor cells: 144.3;Oligodendrocytes: 77.9;Oocytes: 75.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.0" "Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 66: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 3 Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 295.4;Inhibitory neurons: 129.0;Microglial cells: 148.5;Oligodendrocyte precursor cells: 439.1;Oligodendrocytes: 495.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.9" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 5 Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved NA NA 7800000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" "HPA064055: AB_2685183" "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavorable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.6" "Group enriched" "Detected in many" 8 "Astrocytes: 118.9;Excitatory neurons: 256.8;Inhibitory neurons: 265.6;Oligodendrocyte precursor cells: 304.7;Oligodendrocytes: 444.3" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.5" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Skin - Eccrine sweat gland cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" NALF1 "FAM155A, NLF-1" ENSG00000204442 "NALCN channel auxiliary factor 1" B1AL88 13 107163510-107867496 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;pituitary gland: 5.3" "Group enriched" "Detected in many" 6 "Astrocytes: 871.3;Excitatory neurons: 2948.0;Inhibitory neurons: 2059.5;Oligodendrocyte precursor cells: 2165.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039453 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA039453: AB_10795290" "unprognostic (8.40e-2)" "unprognostic (9.98e-3)" "unprognostic (1.48e-1)" "unprognostic (3.38e-3)" "unprognostic (2.69e-1)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (5.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.08e-1)" "unprognostic (4.26e-1)" "unprognostic (9.06e-2)" "unprognostic (1.02e-5)" "unprognostic (5.56e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-2)" "unprognostic (3.69e-3)" NALF2 "CXorf63, FAM155B, TED, TMEM28" ENSG00000130054 "NALCN channel auxiliary factor 2" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 42.0" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 18.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA036093: AB_10673613" "prognostic unfavorable (4.61e-5)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "unprognostic (3.09e-4)" "unprognostic (7.07e-2)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (1.83e-4)" "prognostic favorable (6.63e-4)" "unprognostic (1.46e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-1)" "unprognostic (8.21e-2)" NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 60.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Ciliated cells: 42.5;Cone photoreceptor cells: 49.3;Horizontal cells: 88.1;Muller glia cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 705.1" "Cell type enriched" "Detected in some" 19 "Proximal tubular cells: 1866.0" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "liver cancer: 5.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA067855, HPA074519" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 25 "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" NAT8B "CML2, Hcml2, NAT8BP" ENSG00000204872 "N-acetyltransferase 8B (putative, gene/pseudogene)" 2 73700576-73701340 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "intestine: 48.0;kidney: 33.6" "Group enriched" "Detected in some" 18 "Proximal enterocytes: 138.5;Proximal tubular cells: 109.7" "Group enriched" "Detected in many" 4 "liver cancer: 4.5;renal cancer: 10.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA067855, HPA074519" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.01e-2)" "unprognostic (5.69e-3)" "unprognostic (8.31e-2)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (1.06e-2)" "unprognostic (4.51e-2)" "unprognostic (7.48e-2)" "unprognostic (3.14e-1)" "unprognostic (9.41e-2)" "unprognostic (5.94e-2)" "unprognostic (4.42e-2)" "prognostic favorable (3.24e-5)" "unprognostic (7.93e-3)" "unprognostic (1.04e-2)" "unprognostic (2.13e-2)" "unprognostic (9.78e-5)" NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 42.0;brain: 35.8" "Cell type enhanced" "Detected in many" "Astrocytes: 120.1;Excitatory neurons: 44.6;Granulosa cells: 31.8;Horizontal cells: 86.2;Inhibitory neurons: 36.1;Muller glia cells: 25.4" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Skin - Adipocytes (Skin), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 47: Astrocytes - Unknown function" 1 Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166916-15561340 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 210.5;Inhibitory neurons: 180.1;Oligodendrocyte precursor cells: 149.5;Oligodendrocytes: 148.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: AB_10670925" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (5.84e-5)" NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 27.9;retina: 62.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 981.4;Inhibitory neurons: 912.8;Oligodendrocyte precursor cells: 438.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 44.6" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 193.9;heart muscle: 140.8" "Cell type enhanced" "Detected in many" "Astrocytes: 503.5;Excitatory neurons: 445.6;Inhibitory neurons: 421.9;Oligodendrocyte precursor cells: 881.1;Oligodendrocytes: 943.3;Schwann cells: 249.7" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.9" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 126.4" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" Receptor NA NA 1200000 2300000000 "Cluster 15: NK-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.6;brain: 40.2" "Group enriched" "Detected in some" 13 "Astrocytes: 676.2;Excitatory neurons: 837.2;Inhibitory neurons: 866.9;Oligodendrocyte precursor cells: 1622.5;Oligodendrocytes: 1420.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "prostate cancer: 45.3;Rhabdoid: 16.5" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 60000 "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 32: Smooth muscle cells - Muscle contraction" 7 Cytosol "HPA020449: AB_1854327" "unprognostic (7.92e-3)" "unprognostic (1.24e-2)" "unprognostic (3.35e-2)" "unprognostic (8.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.12e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (5.06e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (2.41e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 43.8" "Cell type enhanced" "Detected in many" "B-cells: 71.0;dendritic cells: 123.1;granulocytes: 62.4;Hofbauer cells: 118.6;Kupffer cells: 143.1;Macrophages: 122.2;monocytes: 149.4;NK-cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Bone cancer: 54.5;Leukemia: 63.4;lymphoma: 53.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Supported "Plasma membrane,Cytosol" NA NA 33000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 117.8" "Cell type enhanced" "Detected in many" "Oocytes: 40.4;Peritubular cells: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019267, HPA050005" Enhanced "Plasma membrane" NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 44: Oocytes - Unknown function" 4 "Plasma membrane" "CAB019267: , HPA050005: AB_2680988" "unprognostic (1.55e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.79e-1)" "unprognostic (9.64e-3)" "unprognostic (5.50e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.20e-5)" "unprognostic (1.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" NCLN "NET59, NICALIN" ENSG00000125912 Nicalin Q969V3 19 3185563-3209575 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006625 Approved Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 2 "Lipid droplets" Nucleoplasm "HPA006625: AB_1079453" "unprognostic (4.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-4)" "unprognostic (8.55e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (9.38e-2)" "unprognostic (2.02e-2)" "unprognostic (1.26e-3)" "prognostic unfavorable (8.37e-5)" "prognostic favorable (8.82e-5)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" NCMAP "C1orf130, FLJ42528, MP11" ENSG00000184454 "Non-compact myelin associated protein" Q5T1S8 1 24556087-24609328 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "gallbladder: 7.1;pancreas: 8.3;salivary gland: 7.6" "Cell type enhanced" "Detected in many" "dendritic cells: 15.8;Ductal cells: 19.8;Exocrine glandular cells: 33.1;Schwann cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.8" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells" "Low region specificity" "Detected in many" HPA013656 Uncertain NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 45: Non-specific - Mixed function" "HPA013656: AB_2275006" "unprognostic (3.38e-2)" "unprognostic (3.52e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.83e-6)" "unprognostic (3.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.73e-1)" "unprognostic (2.41e-2)" "unprognostic (1.04e-1)" "unprognostic (3.28e-3)" "unprognostic (9.88e-2)" "unprognostic (9.53e-2)" "unprognostic (1.63e-2)" "unprognostic (7.27e-3)" NCR2 "CD336, LY95, NK-p44" ENSG00000096264 "Natural cytotoxicity triggering receptor 2" O95944 6 41335608-41350889 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 17 "NK-cell: 1.7;plasmacytoid DC: 4.9" "Group enriched" "Detected in many" 17 "dendritic cells: 4.9;NK-cells: 1.7" "Group enriched" "Detected in some" 23 "Leukemia: 1.3;lymphoma: 3.3" "Not detected" "Not detected" HPA067249 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 2 "HPA067249: AB_2685811" "unprognostic (5.81e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-2)" "unprognostic (1.65e-1)" NCR3LG1 "B7-H6, DKFZp686O24166" ENSG00000188211 "Natural killer cell cytotoxicity receptor 3 ligand 1" Q68D85 11 17351800-17377341 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2;parathyroid gland: 7.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 31.1;Inhibitory neurons: 28.1;Langerhans cells: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" HPA024137 Uncertain NA NA 21000 "Cluster 80: Non-specific - Endocytosis" "Cluster 5: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 9 "HPA024137: AB_1859534" "unprognostic (1.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.52e-2)" "unprognostic (1.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.05e-1)" "unprognostic (7.03e-5)" "unprognostic (6.24e-2)" "unprognostic (1.09e-1)" "unprognostic (3.59e-1)" "unprognostic (2.62e-1)" "unprognostic (2.36e-1)" "prognostic favorable (4.21e-12)" "unprognostic (7.88e-3)" "unprognostic (1.72e-1)" "unprognostic (3.52e-3)" "unprognostic (1.36e-1)" NCSTN "APH2, KIAA0253" ENSG00000162736 Nicastrin Q92542 1 160343294-160358952 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021982, HPA054846, HPA070642" Approved Approved Cytosol NA NA 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 6 Cytosol "CAB021982: , HPA054846: AB_2682624, HPA070642: AB_2686289" "unprognostic (1.08e-1)" "unprognostic (5.22e-3)" "unprognostic (1.51e-1)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-3)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (3.62e-2)" "unprognostic (8.21e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.75e-9)" "unprognostic (1.36e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-2)" "unprognostic (4.89e-2)" NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481155-79556077 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 270.1;Late spermatids: 317.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 28.4" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 3 Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 528.2;Proximal enterocytes: 388.6;Suprabasal keratinocytes: 755.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 414.2" "Colon - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 12 Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2088.5;salivary gland: 2014.6;skeletal muscle: 1758.6" "Cell type enhanced" "Detected in many" "Melanocytes: 432.9;Muller glia cells: 484.6;Serous glandular cells: 988.7" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.5" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.5" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" NDRG4 "KIAA1180, SMAP-8" ENSG00000103034 "NDRG family member 4" Q9ULP0 16 58462846-58513628 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 365.3;heart muscle: 341.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 309.5;Excitatory neurons: 92.5;Horizontal cells: 293.3;Inhibitory neurons: 90.5;Muller glia cells: 71.3;Sertoli cells: 87.0" "Cancer enriched" "Detected in many" 6 "glioma: 23.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 65.0;Rhabdoid: 37.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015313, HPA015779" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 Cytosol "Plasma membrane" "HPA015313: AB_1854343, HPA015779: " "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" "unprognostic (9.03e-3)" "unprognostic (1.59e-2)" "unprognostic (3.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (6.07e-2)" "unprognostic (1.02e-1)" "unprognostic (4.84e-3)" "unprognostic (5.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.22e-2)" "unprognostic (8.51e-2)" "unprognostic (4.45e-2)" "unprognostic (7.17e-2)" NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 1.4;classical monocyte: 5.5;eosinophil: 3.6;intermediate monocyte: 1.7;myeloid DC: 4.2;neutrophil: 5.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 10 "dendritic cells: 4.2;granulocytes: 5.4;monocytes: 5.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "HPA060532: AB_2684310" "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.0;granulocytes: 22.6;monocytes: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA051515: AB_2681517" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3307.0;Distal tubular cells: 2486.4;Proximal tubular cells: 1882.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029768, HPA054359" Enhanced Approved Mitochondria,Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Mitochondria "HPA029768: AB_2673192, HPA054359: AB_2682461" "unprognostic (1.72e-1)" "unprognostic (3.00e-3)" "unprognostic (3.12e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (7.34e-3)" "unprognostic (1.56e-1)" "unprognostic (8.20e-3)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (8.11e-3)" "unprognostic (4.77e-2)" "prognostic favorable (3.48e-4)" "unprognostic (1.16e-1)" "unprognostic (3.62e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-3)" NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072209 Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA072209: AB_2686495" "unprognostic (2.24e-1)" "prognostic favorable (4.54e-5)" "unprognostic (8.20e-3)" "prognostic favorable (3.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.73e-2)" "unprognostic (6.30e-2)" "unprognostic (7.26e-3)" "unprognostic (3.95e-1)" "unprognostic (4.20e-2)" "unprognostic (1.67e-3)" "unprognostic (9.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (6.16e-3)" NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1119.9;Late spermatids: 2382.4;Proximal enterocytes: 1111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 3 Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" NDUFA3 B9 ENSG00000170906 "NADH:ubiquinone oxidoreductase subunit A3" O95167 19 54102728-54109257 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 606.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1944.0;Distal tubular cells: 1115.7;Late spermatids: 1754.4;Proximal tubular cells: 1354.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA046976 Supported NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 14 "HPA046976: AB_10960994" "unprognostic (3.04e-2)" "unprognostic (4.12e-3)" "unprognostic (9.53e-2)" "unprognostic (5.95e-2)" "unprognostic (6.73e-2)" "unprognostic (3.14e-2)" "unprognostic (3.91e-1)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.00e-2)" "prognostic favorable (9.65e-4)" "unprognostic (9.91e-2)" "unprognostic (3.24e-3)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" "prognostic favorable (4.80e-4)" NDUFA4 "CI-9k, COXFA4, MISTR1, MLRQ, MRCAF1" ENSG00000189043 "NDUFA4 mitochondrial complex associated" O00483 7 10931943-10940153 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 627.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4736.0;Distal tubular cells: 3881.7;Proximal tubular cells: 3313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Approved Supported Mitochondria NA NA 50000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.83e-1)" "unprognostic (6.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (2.16e-1)" "unprognostic (4.97e-3)" "unprognostic (3.85e-1)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (3.90e-2)" "unprognostic (8.65e-3)" "unprognostic (1.74e-1)" "prognostic favorable (4.61e-8)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-3)" "unprognostic (2.08e-1)" NDUFA4L2 "COXFA4L2, FLJ26118, MISTRH, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 296.3" "Cell type enhanced" "Detected in many" "Adipocytes: 154.3;Basal keratinocytes: 157.1;Muller glia cells: 635.8;Sertoli cells: 413.4;Smooth muscle cells: 441.2;Suprabasal keratinocytes: 690.7" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Kidney cancer: 406.2" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 620.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Late spermatids - Spermatogenesis" 9 Mitochondria Nucleoplasm "HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (2.26e-1)" "unprognostic (7.85e-3)" "unprognostic (3.67e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (9.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.57e-7)" "unprognostic (7.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.93e-2)" "prognostic favorable (5.75e-4)" NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2582.3;Distal tubular cells: 1745.7;Hepatocytes: 2067.8;Proximal tubular cells: 2096.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear speckles" "HPA063737: AB_2685109" "unprognostic (1.12e-2)" "unprognostic (1.31e-3)" "unprognostic (6.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (6.91e-2)" "unprognostic (3.74e-3)" "unprognostic (5.35e-3)" "unprognostic (4.55e-3)" "unprognostic (1.18e-2)" "unprognostic (4.15e-2)" "prognostic favorable (1.31e-5)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.05e-3)" NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142071-47145466 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 681.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 9 Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 678.9;tongue: 696.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1822.7;Distal tubular cells: 922.0;Proximal tubular cells: 757.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 914.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1549.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 500.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 855.9;Early spermatids: 1109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 897.4;Proximal tubular cells: 893.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 79.7;skeletal muscle: 258.9;tongue: 152.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2840.6;Distal tubular cells: 1226.3;Proximal tubular cells: 1502.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Supported Mitochondria No No "Cluster 46: Basophils - Proteolysis" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 878.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 43: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" NDUFC2-KCTD14 ENSG00000259112 "NDUFC2-KCTD14 readthrough" E9PQ53 11 78016971-78079865 "Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 5.8;Erythroid cells: 3.0;Excitatory neurons: 3.8;Gastric mucus-secreting cells: 2.4;Inhibitory neurons: 3.0;Oligodendrocyte precursor cells: 2.4;Oligodendrocytes: 2.2;Plasma cells: 6.7;Squamous epithelial cells: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 29: Forebrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 49: Non-specific - Transcription" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 448.2;tongue: 608.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 5 Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, Nectin-1, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 125.1;skin 1: 130.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 89.1;Basal squamous epithelial cells: 60.5;Squamous epithelial cells: 109.7;Suprabasal keratinocytes: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 131.1" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" Receptor NA NA 180000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" NECTIN2 "CD112, HVEB, Nectin-2, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 251.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 10 "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 53.0" "Cell type enhanced" "Detected in many" "Early spermatids: 191.3;Excitatory neurons: 214.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 154.2;Syncytiotrophoblasts: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Uncertain "Cell Junctions,Cytosol" NA NA 41000000 "Cluster 46: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 9 "Cell Junctions, Cytosol" "CAB009869: AB_2284699, HPA011038: AB_1079719" "unprognostic (3.76e-2)" "unprognostic (3.81e-3)" "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.26e-3)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (3.94e-2)" "unprognostic (5.33e-2)" "unprognostic (7.04e-2)" "prognostic favorable (9.82e-7)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 110.2;vagina: 55.6" "Cell type enhanced" "Detected in many" "Club cells: 82.3;Ionocytes: 89.5;Squamous epithelial cells: 110.0;Suprabasal keratinocytes: 183.6;Syncytiotrophoblasts: 462.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 27.9" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" Receptor No No 170000 "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1901.3;Inhibitory neurons: 1203.2;Oligodendrocyte precursor cells: 681.5;Oligodendrocytes: 411.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 1 "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 121.3;choroid plexus: 123.3;retina: 82.6" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 629.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.6;naive CD8 T-cell: 111.4" "Lineage enriched" "Detected in many" 10 "T-cells: 111.4" "Group enriched" "Detected in many" 5 "Bone cancer: 132.3;Neuroblastoma: 58.4" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA 6400000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" NEMP1 "KIAA0286, TMEM194, TMEM194A" ENSG00000166881 "Nuclear envelope integral membrane protein 1" O14524 12 57055643-57088063 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014394 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA014394: AB_2204899" "unprognostic (9.24e-2)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" "unprognostic (4.97e-2)" "unprognostic (1.43e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.93e-4)" "unprognostic (8.36e-2)" "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (1.64e-1)" "unprognostic (6.61e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.63e-2)" "unprognostic (7.05e-2)" NEMP2 TMEM194B ENSG00000189362 "Nuclear envelope integral membrane protein 2" A6NFY4 2 190504338-190534722 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 16.7;Oligodendrocyte precursor cells: 26.4;Oligodendrocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA057719 Approved Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 72: Neuronal - Signal transduction" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA057719: AB_2683510" "unprognostic (3.51e-1)" "unprognostic (9.99e-2)" "unprognostic (1.11e-3)" "unprognostic (1.05e-2)" "unprognostic (2.06e-2)" "unprognostic (1.03e-1)" "unprognostic (8.65e-3)" "unprognostic (5.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.61e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.82e-2)" "unprognostic (7.76e-3)" "unprognostic (4.75e-3)" "unprognostic (1.32e-1)" NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 219.8;Excitatory neurons: 120.4;Oligodendrocyte precursor cells: 112.7;Oligodendrocytes: 409.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 390000000 "Cluster 45: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: AB_2150998, HPA027804: AB_10600771, HPA027805: AB_10601755, HPA027806: AB_10601006" "unprognostic (1.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.60e-3)" "unprognostic (3.76e-2)" "unprognostic (5.44e-1)" "unprognostic (3.83e-2)" "unprognostic (8.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.22e-1)" "unprognostic (3.30e-2)" "unprognostic (5.51e-2)" "unprognostic (8.05e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.75e-1)" NEPRO "C3orf17, DKFZP434F2021, NET17" ENSG00000163608 "Nucleolus and neural progenitor protein" Q6NW34 3 113002444-113019861 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069654 Supported Nucleoplasm,Nucleoli Yes No "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 55: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "HPA069654: AB_2686164" "unprognostic (8.45e-3)" "unprognostic (3.84e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (2.29e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (4.98e-2)" "unprognostic (1.72e-2)" "unprognostic (9.29e-3)" "unprognostic (5.40e-2)" "unprognostic (1.69e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (3.28e-2)" NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 26.3;retina: 33.5" "Group enriched" "Detected in some" 14 "Bipolar cells: 216.9;Excitatory neurons: 296.6;Inhibitory neurons: 330.7;Oligodendrocyte precursor cells: 161.8" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 64.5" "Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" Receptor NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.2;Inhibitory neurons: 168.8;monocytes: 52.3;Oligodendrocyte precursor cells: 74.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "HPA013180: AB_1854383" "unprognostic (2.67e-2)" "unprognostic (3.46e-2)" "unprognostic (3.90e-1)" "unprognostic (1.51e-3)" "unprognostic (2.25e-1)" "unprognostic (5.26e-3)" "unprognostic (1.10e-2)" "unprognostic (5.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (5.53e-6)" "unprognostic (3.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.79e-2)" "unprognostic (1.32e-1)" NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 240.9;Excitatory neurons: 314.3;Inhibitory neurons: 395.5;Oligodendrocyte precursor cells: 401.9;Oligodendrocytes: 295.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045502, HPA075627, CAB080363, CAB080365" Uncertain Supported "Nucleoplasm,Plasma membrane" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 3 "Nucleoplasm, Plasma membrane" "CAB080363: , CAB080365: , HPA045502: AB_2679352, HPA075627: " "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 19.5" "Group enriched" "Detected in some" 4 "Hofbauer cells: 25.7;Kupffer cells: 59.0;Macrophages: 29.1;monocytes: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.6" "Group enriched" "Detected in many" 4 "granulocytes: 90.6;monocytes: 48.2" "Cancer enriched" "Detected in single" 10 "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 136.0;Excitatory neurons: 143.4;Horizontal cells: 202.7;Inhibitory neurons: 133.2;Oligodendrocyte precursor cells: 82.5;Oligodendrocytes: 210.9;Rod photoreceptor cells: 191.0" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 20.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 64: Neuronal - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" NFXL1 HOZFP ENSG00000170448 "Nuclear transcription factor, X-box binding like 1" Q6ZNB6 4 47847233-47914667 "Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059132 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA059132: AB_2683917" "unprognostic (5.37e-2)" "unprognostic (2.89e-1)" "unprognostic (5.14e-3)" "unprognostic (6.13e-2)" "unprognostic (1.81e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (1.13e-2)" "unprognostic (6.26e-3)" "unprognostic (8.48e-3)" "unprognostic (8.34e-2)" "unprognostic (4.47e-2)" "unprognostic (4.72e-3)" "unprognostic (8.89e-2)" "unprognostic (3.15e-1)" "unprognostic (6.67e-2)" "unprognostic (8.01e-2)" NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 47.5;Leydig cells: 91.1;Muller glia cells: 142.8;Schwann cells: 28.4;Sertoli cells: 29.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 187.1" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Cancer enhanced" "Detected in many" "Sarcoma: 69.2;skin cancer: 133.4" "Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 13.5" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 8 "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" NGLY1 "FLJ11005, PNG-1, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 437.3;Late spermatids: 1038.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 11: Late spermatids - Unknown function" 12 "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 9800000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 25: Bipolar cells - Visual perception" 52 Vesicles "HPA036335: AB_10696654, HPA036336: AB_2675068, HPA061466: AB_2684532" "unprognostic (6.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (9.52e-5)" "unprognostic (2.48e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.51e-6)" "unprognostic (1.94e-1)" "unprognostic (8.53e-3)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.65e-2)" "unprognostic (6.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-3)" "unprognostic (8.61e-2)" NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.4;choroid plexus: 4.3;pituitary gland: 6.3;retina: 9.9" "Cell type enhanced" "Detected in some" "Astrocytes: 28.2;Cone photoreceptor cells: 35.7;Excitatory neurons: 54.1;Inhibitory neurons: 42.4;Oligodendrocyte precursor cells: 41.0;Oligodendrocytes: 18.9" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.7" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Approved Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA007695: AB_2667897" "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 283.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 582.6;Langerhans cells: 846.8;monocytes: 591.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1675.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 1675.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 16 "HPA045063: AB_10964133" "unprognostic (1.23e-2)" "unprognostic (8.25e-3)" "unprognostic (3.64e-3)" "unprognostic (1.40e-2)" "unprognostic (8.18e-2)" "unprognostic (1.28e-2)" "unprognostic (4.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.82e-2)" "unprognostic (9.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (7.46e-3)" NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663589 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.2" "Cell type enhanced" "Detected in many" "Adipocytes: 27.5;Erythroid cells: 28.6;Hofbauer cells: 36.0;Kupffer cells: 31.7;Oligodendrocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 27.0;lymphoma: 16.2" "Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 51: Oligodendrocytes - Unknown function" 63 "Endoplasmic reticulum" "Plasma membrane" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" NIPA1 "MGC35570, SLC57A1, SPG6" ENSG00000170113 "NIPA magnesium transporter 1" Q7RTP0 15 22773063-22829789 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 56.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 35.0;Inhibitory neurons: 32.4;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023269 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 51: Oligodendrocytes - Unknown function" 2 "HPA023269: AB_1854485" "unprognostic (1.64e-2)" "unprognostic (7.60e-2)" "unprognostic (2.61e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (1.79e-1)" "unprognostic (3.31e-2)" "unprognostic (2.13e-2)" "unprognostic (2.77e-1)" "unprognostic (2.42e-2)" "unprognostic (6.25e-2)" "unprognostic (6.32e-2)" "unprognostic (6.95e-2)" "unprognostic (8.80e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.66e-2)" NIPA2 SLC57A2 ENSG00000140157 "NIPA magnesium transporter 2" Q8N8Q9 15 22838644-22869362 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067160, HPA071342" Approved Approved "Golgi apparatus" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 73: B-cells - B-cell function" "Golgi apparatus" "HPA067160: AB_2685794, HPA071342: AB_2686391" "unprognostic (2.88e-3)" "unprognostic (1.82e-1)" "unprognostic (9.34e-3)" "unprognostic (1.17e-1)" "unprognostic (4.49e-1)" "unprognostic (2.34e-1)" "unprognostic (3.02e-2)" "unprognostic (1.22e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-1)" "unprognostic (2.46e-3)" "unprognostic (2.94e-1)" "unprognostic (7.75e-3)" "unprognostic (3.53e-2)" "unprognostic (1.59e-1)" "unprognostic (3.22e-2)" "unprognostic (2.93e-2)" NIPAL1 "DKFZp686A06115, NPAL1, SLC57A3" ENSG00000163293 "NIPA like domain containing 1" Q6NVV3 4 47914142-48040173 "Predicted membrane proteins" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.1;skin 1: 25.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 38.9;Distal enterocytes: 52.5;Paneth cells: 37.8;Secretory cells: 36.9;Squamous epithelial cells: 52.1;Suprabasal keratinocytes: 76.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036765 Uncertain Approved "Golgi apparatus" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA036765: AB_10672366" "unprognostic (3.03e-1)" "unprognostic (4.55e-2)" "unprognostic (2.34e-3)" "unprognostic (2.18e-2)" "unprognostic (1.12e-2)" "unprognostic (3.57e-1)" "unprognostic (9.55e-2)" "unprognostic (4.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (3.71e-3)" "unprognostic (1.34e-1)" "unprognostic (9.03e-7)" "unprognostic (2.55e-1)" "unprognostic (3.73e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" NIPAL2 "FLJ13955, NPAL2, SLC57A4" ENSG00000104361 "NIPA like domain containing 2" Q9H841 8 98189826-98294393 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 120.6;Squamous epithelial cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071759 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Neurons - Neuronal signaling" "HPA071759: AB_2686443" "unprognostic (5.14e-3)" "unprognostic (6.43e-2)" "unprognostic (8.01e-2)" "unprognostic (2.02e-1)" "unprognostic (4.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.72e-1)" "unprognostic (9.45e-2)" "unprognostic (1.90e-2)" "unprognostic (3.67e-1)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.18e-3)" "unprognostic (1.28e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (4.76e-2)" NIPAL3 "DJ462O23.2, NPAL3, SLC57A5" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.3" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 98.6;Oligodendrocytes: 85.5;Prostatic glandular cells: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Prostatic glandular cells - Transcription" 8 Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" NIPAL4 "ICHYN, SLC57A6" ENSG00000172548 "NIPA like domain containing 4" Q0D2K0 5 157460213-157474722 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" Receptor "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.3;skin 1: 59.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 23.8;Oligodendrocytes: 19.5;Squamous epithelial cells: 8.9;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.0;urothelial cancer: 11.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 25 "memory B-cell: 1.6;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 37 "B-cells: 4.9" "Cancer enhanced" "Detected in many" "Bladder cancer: 10.5;head and neck cancer: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038259 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 15 "HPA038259: AB_10672510" "unprognostic (6.74e-4)" "unprognostic (9.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.49e-1)" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (3.55e-2)" "unprognostic (5.20e-2)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (5.28e-9)" "unprognostic (3.12e-2)" "unprognostic (8.66e-3)" "unprognostic (1.18e-2)" "prognostic favorable (6.82e-4)" NKAIN1 "FAM77C, FLJ12650" ENSG00000084628 "Sodium/potassium transporting ATPase interacting 1" Q4KMZ8 1 31179745-31239887 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "adrenal gland: 23.5;brain: 32.7;skeletal muscle: 18.7;tongue: 11.4" "Cell type enriched" "Detected in some" 11 "Oligodendrocytes: 40.9" "Group enriched" "Detected in many" 5 "breast cancer: 17.2;glioma: 4.6;prostate cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 9.5;Neuroblastoma: 29.5" "Colon - Colon enteroendocrine cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006873 Uncertain NA NA "Cluster 79: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" "HPA006873: AB_1848410" "unprognostic (1.58e-2)" "unprognostic (7.99e-2)" "unprognostic (8.54e-2)" "unprognostic (6.11e-5)" "unprognostic (6.59e-2)" "unprognostic (1.24e-1)" "unprognostic (4.30e-4)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (2.78e-2)" "unprognostic (2.01e-2)" "unprognostic (8.07e-2)" "unprognostic (6.31e-9)" "unprognostic (1.00e-2)" "unprognostic (8.83e-3)" "unprognostic (1.62e-4)" "unprognostic (5.50e-2)" NKAIN2 "FAM77B, TCBA1" ENSG00000188580 "Sodium/potassium transporting ATPase interacting 2" Q5VXU1 6 123803865-124825640 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "brain: 90.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1663.1;Inhibitory neurons: 609.2;Oligodendrocytes: 2670.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in some" "lung cancer: 4.2;thyroid cancer: 7.1" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045860 Approved Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" Cytosol "HPA045860: AB_10983192" "unprognostic (3.09e-2)" "unprognostic (1.06e-2)" "unprognostic (2.33e-2)" "unprognostic (4.53e-3)" "unprognostic (5.67e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.41e-3)" "unprognostic (2.02e-3)" "unprognostic (2.61e-1)" "unprognostic (5.95e-3)" "unprognostic (3.63e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (1.63e-1)" NKAIN3 "FAM77D, FLJ39630, NKAIN3-IT1" ENSG00000185942 "Sodium/potassium transporting ATPase interacting 3" Q8N8D7 8 62248591-63014000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6" "Group enriched" "Detected in many" 6 "Astrocytes: 1193.6;Oligodendrocyte precursor cells: 761.7" "Cancer enriched" "Detected in single" 5 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018833 Enhanced NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" "HPA018833: AB_2669943" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-3)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (3.22e-2)" "unprognostic (3.15e-2)" "unprognostic (1.58e-1)" NKAIN4 "bA261N11.2, C20orf58, FAM77A" ENSG00000101198 "Sodium/potassium transporting ATPase interacting 4" Q8IVV8 20 63240784-63272694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 86.3;kidney: 50.8" "Cell type enriched" "Detected in some" 4 "Proximal tubular cells: 333.7" "Cancer enriched" "Detected in many" 6 "glioma: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 27.2;Uterine cancer: 16.5" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029876 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "HPA029876: AB_10602038" "unprognostic (1.26e-1)" "unprognostic (4.27e-1)" "unprognostic (6.07e-5)" "prognostic unfavorable (3.14e-4)" "unprognostic (6.65e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-3)" "unprognostic (1.94e-1)" "unprognostic (3.62e-2)" "unprognostic (2.69e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.44e-4)" "unprognostic (5.66e-2)" "unprognostic (6.74e-2)" "unprognostic (4.01e-1)" NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 594.5;lymphoid tissue: 150.9" "Cell type enriched" "Detected in many" 5 "NK-cells: 6000.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6845.3;MAIT T-cell: 2877.8;memory CD8 T-cell: 4296.3;naive CD8 T-cell: 3123.7;NK-cell: 4809.3" "Group enriched" "Detected in all" 44 "NK-cells: 4809.3;T-cells: 6845.3" "Group enriched" "Detected in some" 30 "Leukemia: 67.0;lymphoma: 75.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 39 Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149744-45160982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Basal prostatic cells: 1.5;Horizontal cells: 2.5;Spermatocytes: 2.0;Suprabasal keratinocytes: 3.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043339 Uncertain NA NA "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174294372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3;retina: 10.7" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1433.6;Inhibitory neurons: 1626.3;Oligodendrocyte precursor cells: 3757.2;Oligodendrocytes: 1174.3" "Group enriched" "Detected in some" 9 "glioma: 3.8;melanoma: 2.2;renal cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 82000 "Cluster 17: Neuronal - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane" "Nuclear bodies" "CAB033261: AB_2151659, HPA006572: , HPA006680: AB_1854400" "unprognostic (2.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.08e-5)" "unprognostic (7.52e-5)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (3.21e-3)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (4.08e-2)" "unprognostic (8.81e-2)" "unprognostic (2.41e-3)" "unprognostic (5.37e-2)" NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.5;Bipolar cells: 24.7;Endometrial stromal cells: 23.5;Horizontal cells: 29.0;Inhibitory neurons: 23.8;Oligodendrocyte precursor cells: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria NA NA 14000 "Cluster 66: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" Mitochondria "HPA055321: AB_2682783, HPA069278: AB_2686105" "unprognostic (1.31e-1)" "unprognostic (1.87e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-3)" "unprognostic (1.81e-2)" NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144821-71175255 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.0;seminal vesicle: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 18.6;Inhibitory neurons: 12.1;Oligodendrocyte precursor cells: 86.3;Oligodendrocytes: 40.6;Peritubular cells: 16.3;Schwann cells: 17.6" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.5" "Colon - Enteric glia cells, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" NLGN4X "HLNX, KIAA1260, NLGN, NLGN4" ENSG00000146938 "Neuroligin 4 X-linked" Q8N0W4 X 5840637-6228867 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.2;lymphoid tissue: 13.9;ovary: 14.2" "Cell type enhanced" "Detected in many" "Astrocytes: 108.1;Excitatory neurons: 156.7;Inhibitory neurons: 227.0;Oligodendrocyte precursor cells: 659.4" "Group enriched" "Detected in many" 4 "endometrial cancer: 2.7;glioma: 8.5;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 24.2;testis cancer: 39.3" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Testis - Spermatogonia" HPA001651 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA001651: AB_1079470" "unprognostic (2.21e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (8.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.67e-1)" "unprognostic (9.49e-2)" "unprognostic (1.48e-2)" "unprognostic (9.32e-2)" "unprognostic (5.10e-3)" "unprognostic (7.16e-4)" "unprognostic (6.70e-2)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" NLGN4Y KIAA0951 ENSG00000165246 "Neuroligin 4 Y-linked" Q8NFZ3 Y 14522573-14845654 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 7.1" "Cell type enhanced" "Detected in many" "Astrocytes: 45.5;Basal squamous epithelial cells: 37.2;Excitatory neurons: 141.1;Inhibitory neurons: 103.3;Oligodendrocyte precursor cells: 207.1;Oligodendrocytes: 43.3" "Cancer enhanced" "Detected in many" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 18.3" HPA001651 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 34: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA001651: AB_1079470" "unprognostic (2.31e-1)" "unprognostic (9.19e-2)" "unprognostic (2.84e-5)" "unprognostic (7.85e-2)" "unprognostic (6.46e-2)" "unprognostic (8.80e-3)" "unprognostic (7.71e-2)" "unprognostic (6.26e-2)" "unprognostic (5.89e-2)" "unprognostic (7.20e-3)" "unprognostic (1.88e-1)" "unprognostic (5.65e-2)" NMBR "BB1, BB1R, BRS1" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142147122 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Early spermatids: 8.9;Excitatory neurons: 2.3;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 1.9;Oligodendrocytes: 2.4;Spermatocytes: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 7.9" "Cell type enhanced" "Detected in some" "NK-cells: 32.1;Peritubular cells: 7.6;Rod photoreceptor cells: 17.5;T-cells: 6.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 18.0;MAIT T-cell: 4.5;memory CD8 T-cell: 8.7;naive CD8 T-cell: 5.1;NK-cell: 10.9" "Group enriched" "Detected in many" 23 "NK-cells: 10.9;T-cells: 18.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.0;testis: 1.5" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 3.5;Oligodendrocytes: 7.9;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.5;pancreatic cancer: 8.1" "Testis - Sertoli cells" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" 3 "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 230.4;tongue: 369.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 466.8;Hepatocytes: 361.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975, HPA066564" Enhanced Approved Mitochondria NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Mitochondria "CAB004975: AB_425908, HPA004829: AB_1079495, HPA066564: " "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" NOL6 "bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22" ENSG00000165271 "Nucleolar protein 6" Q9H6R4 9 33461353-33473930 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.0;Late spermatids: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055891, HPA061002" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoli Nucleoplasm "HPA055891: AB_2682959, HPA061002: AB_2684410" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (2.37e-1)" "unprognostic (5.23e-2)" "unprognostic (2.32e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (4.83e-5)" "unprognostic (7.37e-3)" "unprognostic (8.26e-2)" "unprognostic (3.03e-2)" "unprognostic (2.09e-1)" "unprognostic (4.24e-2)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (4.09e-1)" NOMO1 PM5 ENSG00000103512 "NODAL modulator 1" Q15155 16 14833721-14896157 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 130.0" "Cell type enhanced" "Detected in many" "Early spermatids: 36.1;Exocrine glandular cells: 35.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "hypothalamus: 14.0" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "CAB025192, HPA046697, HPA061174" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 57: Platelets - Hemostasis" "Endoplasmic reticulum" "CAB025192: , HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (5.33e-3)" "unprognostic (1.60e-1)" "unprognostic (5.27e-1)" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.51e-1)" "unprognostic (4.18e-3)" "unprognostic (2.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-2)" "unprognostic (8.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.50e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (3.15e-4)" NOMO2 "NOMO, PM5" ENSG00000185164 "NODAL modulator 2" Q5JPE7 16 18417325-18562211 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.2;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 7.1;Plasma cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA046697, HPA061174" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (2.58e-3)" "unprognostic (4.11e-3)" "unprognostic (2.58e-2)" "unprognostic (9.10e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-2)" "unprognostic (4.80e-2)" "unprognostic (9.37e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (1.09e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-3)" "unprognostic (2.22e-1)" "unprognostic (3.42e-2)" "unprognostic (8.39e-2)" "unprognostic (1.54e-2)" NOMO3 ENSG00000103226 "NODAL modulator 3" P69849 16 16232506-16300806 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 29.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "HPA046697, HPA061174" Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" "HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (1.21e-1)" "unprognostic (1.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.33e-1)" "unprognostic (9.81e-2)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (8.02e-2)" "unprognostic (6.25e-2)" "unprognostic (8.43e-2)" "unprognostic (7.86e-3)" "unprognostic (1.82e-1)" "unprognostic (1.65e-1)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 53.8;Astrocytes: 63.8;Endothelial cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 11 Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" 1 "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 176.8;Smooth muscle cells: 301.5;Squamous epithelial cells: 76.1;Suprabasal keratinocytes: 91.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 85.0" "Lung - Smooth muscle cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392, HPA067424" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 46000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Nucleoplasm, Plasma membrane" "CAB005393: AB_2151246, HPA044392: AB_2678926, HPA067424: " "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" NOX3 GP91-3 ENSG00000074771 "NADPH oxidase 3" Q9HBY0 6 155395368-155455839 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "granulocytes: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA073837 Uncertain Vesicles NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 Vesicles "HPA073837: " "unprognostic (3.42e-1)" NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 71.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 2 "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" NPC1L1 SLC65A2 ENSG00000015520 "NPC1 like intracellular cholesterol transporter 1" Q9UHC9 7 44512535-44541330 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 52.7;liver: 46.9" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 33.5" "Group enriched" "Detected in many" 5 "liver cancer: 8.5;pancreatic cancer: 7.8;stomach cancer: 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gastric cancer: 9.2;liver cancer: 7.6" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB070127, CAB070128" Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" "CAB070127: AB_10002744, CAB070128: AB_10000815" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-3)" "unprognostic (8.43e-2)" "unprognostic (1.62e-1)" "unprognostic (2.07e-1)" "unprognostic (9.40e-2)" "unprognostic (6.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.96e-2)" "unprognostic (4.51e-2)" "unprognostic (7.59e-2)" "unprognostic (8.08e-10)" "unprognostic (1.64e-2)" "unprognostic (2.83e-1)" "unprognostic (3.62e-2)" "unprognostic (5.83e-2)" NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 425.6;Endothelial cells: 321.0;Intestinal goblet cells: 603.5;Prostatic glandular cells: 360.6" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.1;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 27 Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" NPFFR1 "GPR147, NPFF1R1, OT7T022" ENSG00000148734 "Neuropeptide FF receptor 1" Q9GZQ6 10 70247329-70284004 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;retina: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Granulosa cells: 3.5;Muller glia cells: 8.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "basal ganglia: 15.7;hypothalamus: 6.3" "Low region specificity" "Detected in some" HPA037521 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" 2 "HPA037521: AB_2675520" "unprognostic (1.73e-3)" "unprognostic (7.29e-4)" "unprognostic (2.12e-1)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (8.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (3.51e-1)" "unprognostic (9.62e-2)" "unprognostic (6.78e-2)" "unprognostic (5.84e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031902-72148305 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.0;seminal vesicle: 3.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.8;Cytotrophoblasts: 6.8;Excitatory neurons: 13.9;Extravillous trophoblasts: 13.7;Oocytes: 8.8;Syncytiotrophoblasts: 10.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 71: Thymus - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Excitatory neurons: 45.5;Inhibitory neurons: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 78: Testis - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 34: Neurons - Neuronal signaling" 6 "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" NPHS1 "CNF, NPHN" ENSG00000161270 "NPHS1 adhesion molecule, nephrin" O60500 19 35825372-35869287 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Myogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 40.3;pancreas: 22.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 49.8;Collecting duct cells: 68.1;Early spermatids: 15.9;Exocrine glandular cells: 20.6;Glandular and luminal cells: 22.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB035555 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "CAB035555: " "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" "unprognostic (1.65e-1)" "unprognostic (2.39e-2)" "unprognostic (6.47e-3)" "unprognostic (2.25e-2)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (3.32e-2)" "unprognostic (3.17e-1)" "unprognostic (3.83e-5)" "unprognostic (4.30e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" NPHS2 "PDCN, SRN1" ENSG00000116218 "NPHS2 stomatin family member, podocin" Q9NP85 1 179550539-179575952 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 141 "kidney: 248.0" "Cell type enriched" "Detected in some" 5 "Collecting duct cells: 35.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB037267, HPA049486" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 13: Spermatids - Transcription" 1 "CAB037267: AB_261982, HPA049486: AB_2680788" "unprognostic (6.77e-2)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" NPIPA1 "morpheus, NPIP" ENSG00000183426 "Nuclear pore complex interacting protein family member A1" Q9UND3 16 14922802-14952060 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 354.8" "Cell type enhanced" "Detected in many" "Early spermatids: 29.6;Excitatory neurons: 36.5;Inhibitory neurons: 26.1;Late spermatids: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Supported Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.77e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (2.52e-1)" "unprognostic (2.87e-2)" "unprognostic (2.29e-2)" "unprognostic (9.21e-2)" "unprognostic (1.65e-2)" "unprognostic (5.12e-2)" "unprognostic (1.08e-1)" "unprognostic (8.82e-3)" "unprognostic (3.65e-2)" "unprognostic (1.74e-7)" "unprognostic (2.28e-1)" "unprognostic (8.76e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-5)" NPIPA2 ENSG00000254852 "Nuclear pore complex interacting protein family member A2" E9PIF3 16 14742533-14765462 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Early spermatids: 3.6;Excitatory neurons: 2.1;Inhibitory neurons: 1.4;Late spermatids: 2.1;Oligodendrocytes: 1.6;Spermatocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 5: Rhabdoid - Unknown function" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" NPIPA3 ENSG00000224712 "Nuclear pore complex interacting protein family member A3" F8WFD2 16 14703411-14726342 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 26.8" "Cell type enhanced" "Detected in single" "Kupffer cells: 1.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 13: Non-specific - Mixed function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.44e-1)" "unprognostic (7.83e-3)" "unprognostic (8.12e-3)" "unprognostic (1.87e-1)" "unprognostic (1.60e-1)" "unprognostic (5.69e-3)" "unprognostic (3.11e-2)" "unprognostic (4.58e-3)" "unprognostic (4.87e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (1.67e-3)" "unprognostic (1.20e-3)" "unprognostic (1.35e-1)" "unprognostic (1.79e-2)" "unprognostic (1.71e-2)" NPIPA5 ENSG00000183793 "Nuclear pore complex interacting protein family member A5" E9PKD4 16 15363628-15381047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 168.2" "Cell type enhanced" "Detected in many" "Astrocytes: 8.4;Basal squamous epithelial cells: 7.5;Early spermatids: 16.5;Excitatory neurons: 9.9;Inhibitory neurons: 7.8;Late spermatids: 7.9;Oligodendrocyte precursor cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.20e-1)" "unprognostic (1.52e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (4.19e-4)" "unprognostic (5.85e-2)" "unprognostic (5.92e-2)" "unprognostic (7.85e-2)" "unprognostic (6.58e-2)" "unprognostic (9.02e-3)" "unprognostic (1.57e-2)" "unprognostic (4.34e-3)" "unprognostic (1.85e-1)" "unprognostic (2.85e-1)" "unprognostic (9.18e-2)" "unprognostic (4.02e-2)" NPIPA7 ENSG00000214967 "Nuclear pore complex interacting protein family member A7" E9PJI5 16 16379140-16393972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 82.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" 2 Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.17e-2)" NPIPA8 LCR16a9 ENSG00000214940 "Nuclear pore complex interacting protein family member A8" P0DM63 16 18317919-18336736 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 107.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 41.0" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.68e-1)" "unprognostic (3.60e-2)" "unprognostic (2.81e-1)" NPIPA9 ENSG00000183889 "Nuclear pore complex interacting protein family, member A9" 16 16317444-16350590 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in all" "brain: 543.3" "Cell type enhanced" "Detected in some" "Lymphatic endothelial cells: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.91e-1)" "unprognostic (3.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (8.96e-2)" "unprognostic (2.31e-2)" "unprognostic (3.69e-3)" "unprognostic (1.27e-1)" "unprognostic (1.32e-1)" "unprognostic (5.45e-7)" "unprognostic (1.22e-2)" "unprognostic (5.04e-6)" "unprognostic (6.04e-2)" "unprognostic (9.80e-2)" "unprognostic (1.79e-1)" "unprognostic (2.22e-3)" NPIPA9 ENSG00000233024 "Nuclear pore complex interacting protein family, member A9" 16 18358086-18379331 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in all" "brain: 587.4" "Cell type enhanced" "Detected in some" "Intestinal goblet cells: 1.1;Pancreatic endocrine cells: 1.7;Paneth cells: 1.5;Undifferentiated cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (9.10e-2)" "unprognostic (6.00e-3)" "unprognostic (1.66e-1)" "unprognostic (5.77e-2)" "unprognostic (8.31e-2)" "unprognostic (6.34e-2)" "unprognostic (6.34e-2)" "unprognostic (6.76e-2)" "unprognostic (1.30e-3)" "unprognostic (5.87e-2)" "unprognostic (5.79e-3)" "unprognostic (1.60e-2)" "unprognostic (1.25e-5)" "unprognostic (1.96e-1)" "unprognostic (1.90e-2)" "unprognostic (5.38e-2)" "unprognostic (6.45e-3)" NPIPB11 ENSG00000254206 "Nuclear pore complex interacting protein family member B11" E5RHQ5 16 29381310-29406711 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.0;Early spermatids: 7.2;Enteroendocrine cells: 6.7;Inhibitory neurons: 5.2;Intestinal goblet cells: 5.6;Late spermatids: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (6.82e-2)" "unprognostic (2.99e-1)" "unprognostic (1.93e-3)" "unprognostic (1.42e-1)" "unprognostic (1.14e-1)" "unprognostic (6.92e-3)" "unprognostic (3.06e-1)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (5.57e-4)" "unprognostic (7.41e-2)" "unprognostic (2.94e-6)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "unprognostic (5.96e-3)" "unprognostic (4.79e-5)" NPIPB12 ENSG00000169203 "Nuclear pore complex interacting protein family member B12" F8W0I5 16 29483534-29506408 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Plasma cells: 1.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 30.5" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 61: Plasma cells - Immunoglobulins & histones" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (3.83e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "unprognostic (7.92e-2)" "unprognostic (1.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (5.20e-2)" "unprognostic (2.42e-1)" "unprognostic (6.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.28e-7)" "unprognostic (3.32e-2)" "unprognostic (4.11e-2)" "unprognostic (2.33e-1)" "unprognostic (2.14e-4)" NPIPB13 ENSG00000198064 "Nuclear pore complex interacting protein family, member B13" A6NJU9 16 30222897-30255268 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Intestinal goblet cells: 3.5;Late spermatids: 3.6;Melanocytes: 3.4;Microglial cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (7.11e-3)" "unprognostic (4.08e-2)" "unprognostic (1.83e-1)" "unprognostic (1.89e-3)" "unprognostic (4.87e-2)" "unprognostic (2.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (7.69e-2)" "unprognostic (3.67e-1)" "unprognostic (1.41e-1)" "unprognostic (3.09e-7)" "unprognostic (1.86e-2)" "unprognostic (2.98e-1)" "unprognostic (3.17e-1)" "unprognostic (2.58e-2)" NPIPB15 "LOC440348, NPIPL2" ENSG00000196436 "Nuclear pore complex interacting protein family member B15" A6NHN6 16 74376306-74392115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.4" "Group enriched" "Detected in many" 4 "Early spermatids: 286.0;Late spermatids: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA011188, HPA053611" Supported Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (2.23e-2)" "unprognostic (3.48e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-1)" "unprognostic (9.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" "unprognostic (5.53e-2)" "unprognostic (2.41e-2)" "unprognostic (7.73e-2)" "unprognostic (4.58e-3)" "unprognostic (1.53e-1)" "unprognostic (2.81e-2)" "unprognostic (1.97e-1)" "unprognostic (7.34e-3)" "unprognostic (2.53e-1)" "unprognostic (1.14e-3)" NPIPB2 ENSG00000234719 "Nuclear pore complex interacting protein family member B2" A6NJ64 16 11927259-11976643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 52.7;Late spermatids: 63.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" HPA053611 Supported Approved Nucleoplasm NA NA "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (8.80e-2)" "unprognostic (4.83e-1)" "unprognostic (5.20e-2)" "unprognostic (8.24e-2)" "unprognostic (2.45e-1)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.73e-1)" "unprognostic (5.92e-2)" "unprognostic (3.01e-3)" "unprognostic (2.80e-2)" "unprognostic (2.21e-1)" "unprognostic (4.89e-3)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (2.25e-1)" "unprognostic (2.58e-2)" NPIPB3 "KIAA0220, NPIPL3" ENSG00000169246 "Nuclear pore complex interacting protein family member B3" Q92617 16 21402237-21448567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Excitatory neurons: 1.7;Gastric mucus-secreting cells: 1.2;Inhibitory neurons: 1.2;Microglial cells: 1.8;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 33.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 49: Non-specific - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "unprognostic (8.01e-2)" "unprognostic (9.97e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-2)" "unprognostic (3.14e-1)" "unprognostic (3.91e-1)" "unprognostic (1.65e-1)" "unprognostic (4.66e-5)" "unprognostic (1.50e-7)" "unprognostic (1.30e-1)" "unprognostic (3.02e-2)" "unprognostic (5.94e-2)" "unprognostic (9.00e-4)" NPIPB4 ENSG00000185864 "Nuclear pore complex interacting protein family member B4" C9JG80 16 21834569-21880827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 141.8;Excitatory neurons: 246.6;Inhibitory neurons: 174.9;Late spermatids: 89.0;Microglial cells: 374.0;Oligodendrocyte precursor cells: 194.8;Oligodendrocytes: 202.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (3.09e-3)" "unprognostic (3.51e-3)" "unprognostic (4.01e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.82e-2)" "unprognostic (3.66e-1)" "unprognostic (1.76e-1)" "unprognostic (4.05e-3)" "unprognostic (6.04e-8)" "unprognostic (3.37e-1)" "unprognostic (7.78e-2)" "unprognostic (2.32e-1)" "unprognostic (5.46e-3)" NPIPB5 ENSG00000243716 "Nuclear pore complex interacting protein family member B5" A8MRT5 16 22479121-22536535 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 50.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (7.52e-4)" "unprognostic (2.08e-1)" "unprognostic (2.32e-2)" "unprognostic (9.43e-3)" "unprognostic (3.96e-1)" "unprognostic (2.64e-3)" "unprognostic (2.40e-3)" "unprognostic (4.20e-2)" "unprognostic (1.65e-1)" "unprognostic (4.19e-2)" "unprognostic (1.09e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-10)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (3.86e-2)" "unprognostic (3.76e-5)" NPIPB6 ENSG00000198156 "Nuclear pore complex interacting protein family member B6" E9PJ23 16 28342517-28363508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 38.6" "Group enriched" "Detected in some" 22 "Early spermatids: 213.5;Late spermatids: 203.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.7" "Testis - Early spermatids, Testis - Late spermatids" "HPA011188, HPA053611" Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (7.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.86e-2)" "unprognostic (2.43e-1)" "unprognostic (3.21e-1)" "unprognostic (1.02e-1)" "unprognostic (1.54e-1)" "unprognostic (1.31e-1)" "unprognostic (2.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.79e-4)" "unprognostic (3.20e-1)" "unprognostic (8.36e-2)" "unprognostic (4.78e-1)" "unprognostic (1.04e-3)" NPIPB7 "LOC440350, NPIPL1" ENSG00000233232 "Nuclear pore complex interacting protein family member B7" O75200 16 28456329-28472336 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 20.4" "Group enriched" "Detected in some" 25 "Early spermatids: 34.1;Late spermatids: 63.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA011188, HPA053611" Approved Approved Nucleoplasm "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 21: Testis - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-3)" "unprognostic (3.35e-2)" "unprognostic (3.44e-1)" "unprognostic (2.78e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (4.40e-1)" "unprognostic (2.22e-1)" "unprognostic (7.73e-2)" "unprognostic (2.03e-2)" NPIPB8 ENSG00000255524 "Nuclear pore complex interacting protein family member B8" E9PQR5 16 28637654-28658744 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "testis: 17.6" "Group enriched" "Detected in some" 12 "Early spermatids: 12.2;Late spermatids: 33.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "HPA011188, HPA053611" Uncertain Approved Nucleoplasm NA NA "Cluster 78: Testis - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (8.28e-2)" "unprognostic (1.88e-1)" "unprognostic (1.10e-1)" "unprognostic (5.78e-2)" "unprognostic (1.05e-2)" "unprognostic (2.64e-1)" "unprognostic (1.19e-1)" NPIPB9 ENSG00000196993 "Nuclear pore complex interacting protein family member B9" 16 28751787-28772864 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 13.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.6" "HPA011188, HPA053611" Approved Approved Nucleoplasm NA NA "Cluster 21: Testis - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (7.38e-2)" "unprognostic (6.63e-4)" "unprognostic (6.63e-2)" "unprognostic (5.05e-2)" "unprognostic (5.53e-2)" "unprognostic (4.44e-2)" "unprognostic (1.53e-1)" "unprognostic (9.36e-2)" "unprognostic (7.52e-2)" "unprognostic (2.84e-1)" "unprognostic (2.86e-1)" "unprognostic (2.31e-1)" "unprognostic (4.71e-2)" NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.8" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Alveolar cells type 2: 25.0;Endothelial cells: 49.3;Fibroblasts: 35.2;Secretory cells: 87.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9;ovarian cancer: 7.8;Rhabdoid: 6.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" NPR3 "ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC" ENSG00000113389 "Natriuretic peptide receptor 3" P17342 5 32689070-32791724 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 37.0;Cardiomyocytes: 33.3;Distal tubular cells: 36.9;Granulosa cells: 40.7;Proximal tubular cells: 130.3" "Cancer enhanced" "Detected in many" "renal cancer: 19.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 3.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5" "Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052702 Supported Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" Cytosol "HPA052702: AB_2681922" "unprognostic (8.56e-3)" "unprognostic (1.54e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (7.64e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-2)" "unprognostic (9.28e-2)" "unprognostic (6.78e-3)" "unprognostic (1.76e-1)" "unprognostic (6.07e-2)" "unprognostic (3.46e-3)" "prognostic favorable (5.43e-6)" "unprognostic (6.00e-4)" "unprognostic (5.74e-2)" "unprognostic (2.80e-2)" "unprognostic (3.38e-2)" NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 209.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" NPY4R "PP1, PPYR1, Y4" ENSG00000204174 "Neuropeptide Y receptor Y4" P50391 10 46461099-46465958 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 5.8;skin 1: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bile duct cancer: 10.5" "Prostate - Prostate glandular cells" HPA027863 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "HPA027863: AB_10602819" "unprognostic (2.26e-6)" "unprognostic (2.94e-1)" "unprognostic (8.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-3)" "unprognostic (1.98e-1)" "unprognostic (2.64e-3)" "unprognostic (6.58e-2)" "unprognostic (9.79e-2)" NPY4R2 CH17-360D5.1 ENSG00000264717 "Neuropeptide Y receptor Y4-2" P0DQD5 10 47918662-47923524 "Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027863 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "HPA027863: AB_10602819" "unprognostic (1.74e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-1)" "unprognostic (7.78e-2)" "unprognostic (6.72e-3)" "unprognostic (1.23e-1)" "unprognostic (1.46e-2)" "unprognostic (3.25e-1)" NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.3" "Group enriched" "Detected in many" 9 "Astrocytes: 580.9;Excitatory neurons: 738.4;Inhibitory neurons: 375.6;Oligodendrocyte precursor cells: 1181.5" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 15 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" "Cell adhesion" NA NA 110000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" NRDE2 "C14orf102, FLJ14051" ENSG00000119720 "NRDE-2, necessary for RNA interference, domain containing" Q9H7Z3 14 90267860-90331969 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, DNA damage, Mitosis, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047050, HPA050583" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Non-specific - Transcription" 7 "Nucleoplasm, Mitochondria" "HPA047050: AB_2679917, HPA050583: AB_2681182" "unprognostic (1.24e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-1)" "unprognostic (3.02e-1)" "unprognostic (4.51e-2)" "unprognostic (1.08e-2)" "unprognostic (9.60e-2)" "unprognostic (8.91e-3)" "unprognostic (1.10e-1)" "unprognostic (4.88e-3)" "unprognostic (3.26e-3)" "unprognostic (1.35e-2)" "unprognostic (2.31e-3)" "unprognostic (8.27e-2)" "unprognostic (6.56e-2)" "unprognostic (3.13e-2)" "unprognostic (3.49e-2)" NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.5" "Group enriched" "Detected in many" 13 "Excitatory neurons: 1418.8;Inhibitory neurons: 389.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 53.9" "Lineage enriched" "Detected in many" 5 "monocytes: 53.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" "Growth factor" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 67.8;Excitatory neurons: 86.9;Inhibitory neurons: 130.9;Oligodendrocyte precursor cells: 133.5;Oligodendrocytes: 47.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" No NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" 1 Nucleoplasm Nucleoli "HPA038935: AB_10672833, HPA047973: AB_2680226" "unprognostic (8.66e-4)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (6.04e-2)" "unprognostic (3.22e-1)" "unprognostic (2.96e-2)" "unprognostic (8.66e-3)" "unprognostic (1.11e-1)" "unprognostic (3.99e-1)" "unprognostic (1.88e-1)" "unprognostic (4.26e-3)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-2)" "unprognostic (2.23e-2)" "unprognostic (2.07e-2)" NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3" "Group enriched" "Detected in some" 18 "Astrocytes: 2770.9;Excitatory neurons: 3634.2;Inhibitory neurons: 2955.4;Oligodendrocyte precursor cells: 1102.7" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.1;skin cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular Endothelial cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" "Growth factor" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 4.2" "Cell type enhanced" "Detected in many" "Early spermatids: 18.6;Exocrine glandular cells: 22.4;Gastric mucus-secreting cells: 31.2;Oocytes: 27.9;Prostatic glandular cells: 15.6;Rod photoreceptor cells: 28.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" "Growth factor" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" 4 "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 15.6;ovary: 23.8;placenta: 23.4" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 79.2;Leydig cells: 115.4;Syncytiotrophoblasts: 63.7" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in some" 11 "cerebellum: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "testis cancer: 37.3" "Heart muscle - Fibroblasts, Kidney - Ascending Loop of Henle cells, Skeletal muscle - Fibroblasts" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 53.1" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" NRM NRM29 ENSG00000137404 Nurim Q8IXM6 6 30688047-30691420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 29.9;Late spermatids: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072545, HPA073982" Enhanced "Nuclear membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 50 "Nuclear membrane" "HPA072545: AB_2686532, HPA073982: AB_2686649" "unprognostic (2.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.71e-1)" "unprognostic (2.32e-2)" "unprognostic (3.13e-3)" "unprognostic (1.30e-1)" "unprognostic (8.44e-2)" "unprognostic (1.32e-2)" "unprognostic (2.87e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.52e-8)" "unprognostic (3.95e-2)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 336.4;Endothelial cells: 161.7;Hofbauer cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.4" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved Uncertain Mitochondria "Secreted in other tissues" Receptor NA NA 780000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Mitochondria "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.8;Langerhans cells: 178.1;Lymphatic endothelial cells: 478.9;Ovarian stromal cells: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 122.1" "Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" Receptor NA NA 29000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" NRROS "ELLP3030, GARPL1, LRRC33, MGC50789, UNQ3030" ENSG00000174004 "Negative regulator of reactive oxygen species" Q86YC3 3 196639694-196662004 "Disease related genes, Predicted membrane proteins" "Growth factor binding" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.2" "Cell type enhanced" "Detected in some" "B-cells: 36.9;dendritic cells: 42.5;Erythroid cells: 27.1;Hofbauer cells: 72.4;Kupffer cells: 34.1;Langerhans cells: 76.9;Macrophages: 28.8;Microglial cells: 30.4;NK-cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 4.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.3;granulocytes: 4.2;monocytes: 1.1" "Cancer enhanced" "Detected in many" "Leukemia: 76.1;Myeloma: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031586 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA031586: AB_10601543" "unprognostic (5.28e-2)" "unprognostic (8.92e-3)" "unprognostic (1.02e-1)" "unprognostic (3.05e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-3)" "unprognostic (1.05e-1)" "unprognostic (9.67e-2)" "unprognostic (3.20e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (6.73e-3)" "unprognostic (1.47e-1)" "unprognostic (7.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" NRSN1 "p24, VMP" ENSG00000152954 "Neurensin 1" Q8IZ57 6 24126186-24154900 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 78.3;pituitary gland: 22.9;retina: 21.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 25.0;Excitatory neurons: 134.4;Horizontal cells: 49.1;Inhibitory neurons: 107.2;Oligodendrocyte precursor cells: 65.6" "Cancer enriched" "Detected in single" 17 "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 35.5" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019681, HPA061006" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 6 "Plasma membrane, Cytosol" "HPA019681: , HPA061006: AB_2684413" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (8.00e-3)" "unprognostic (8.01e-3)" "unprognostic (1.70e-1)" "unprognostic (4.53e-3)" "unprognostic (7.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.40e-3)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" NRSN2 "C20orf98, dJ1103G7.6" ENSG00000125841 "Neurensin 2" Q9GZP1 20 346782-359660 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015967 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" 1 Vesicles "Nucleoplasm, Cytosol" "HPA015967: AB_1854647" "unprognostic (5.67e-2)" "unprognostic (3.47e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (4.05e-2)" "unprognostic (4.48e-2)" "unprognostic (1.48e-1)" "unprognostic (4.96e-2)" "unprognostic (5.92e-2)" "prognostic favorable (1.61e-4)" "unprognostic (6.96e-2)" "unprognostic (1.96e-3)" "unprognostic (2.94e-2)" "unprognostic (1.96e-1)" "unprognostic (7.85e-3)" "unprognostic (1.73e-3)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 78.6" "Group enriched" "Detected in many" 5 "Astrocytes: 3817.5;Excitatory neurons: 3094.7;Inhibitory neurons: 2015.5;Oligodendrocyte precursor cells: 4595.9" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "lung cancer: 4.4;thyroid cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 65: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" NRXN3 "C14orf60, KIAA0743" ENSG00000021645 "Neurexin 3" "Q9HDB5, Q9Y4C0" 14 78170373-79868291 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.2;retina: 41.7" "Group enriched" "Detected in many" 11 "Excitatory neurons: 3410.9;Inhibitory neurons: 4866.1;Oligodendrocytes: 1995.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002727 Approved NA NA 710000 "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "HPA002727: AB_1079468" "unprognostic (7.96e-2)" "unprognostic (5.70e-4)" "unprognostic (8.18e-3)" "unprognostic (2.19e-2)" "unprognostic (2.31e-4)" "unprognostic (9.56e-2)" "unprognostic (2.80e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-2)" "unprognostic (7.91e-2)" "unprognostic (2.40e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.83e-7)" "unprognostic (4.81e-2)" "unprognostic (2.61e-1)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Hepatocytes - Metabolism" 3 "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" NSG2 "CALY3, HMP19" ENSG00000170091 "Neuronal vesicle trafficking associated 2" Q9Y328 5 174045706-174243501 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 417.0" "Cell type enhanced" "Detected in some" "Early spermatids: 33.1;Excitatory neurons: 43.8;Horizontal cells: 90.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 92.9" "Cancer enriched" "Detected in some" 8 "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 170.6;thyroid cancer: 79.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046531, HPA056191" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "Golgi apparatus" "HPA046531: AB_2732528, HPA056191: AB_2683062" "unprognostic (1.25e-2)" "unprognostic (1.36e-1)" "unprognostic (3.27e-1)" "unprognostic (3.36e-5)" "unprognostic (1.93e-1)" "unprognostic (2.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.07e-1)" "unprognostic (3.29e-1)" "unprognostic (1.76e-1)" "unprognostic (3.86e-3)" "unprognostic (8.06e-2)" "unprognostic (2.29e-2)" "unprognostic (3.02e-2)" "unprognostic (5.20e-2)" "unprognostic (9.31e-4)" "unprognostic (1.55e-1)" NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.6;retina: 91.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 62.3;Lymphatic endothelial cells: 88.9;Oligodendrocyte precursor cells: 57.5;Paneth cells: 56.8;Rod photoreceptor cells: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.1;naive CD8 T-cell: 30.8" "Group enriched" "Detected in many" 41 "B-cells: 33.1;T-cells: 30.8" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 320.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 3000000 "Cluster 34: B-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.4;retina: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2052.6;Cone photoreceptor cells: 479.2;Excitatory neurons: 629.2;Inhibitory neurons: 1013.1;Oligodendrocyte precursor cells: 1811.6;Oligodendrocytes: 1170.5;Rod photoreceptor cells: 1290.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.5" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.5" "Cancer enhanced" "Detected in many" "Bone cancer: 21.7;Brain cancer: 21.9;Sarcoma: 22.1;thyroid cancer: 21.7" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 58000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 28: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 4 "CAB024875: " "unprognostic (1.52e-2)" "unprognostic (4.38e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-1)" "unprognostic (1.07e-1)" "unprognostic (9.99e-3)" "unprognostic (9.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.10e-8)" "unprognostic (4.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (9.31e-3)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815636-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 6.8" "Group enriched" "Detected in some" 6 "Bipolar cells: 25.1;granulocytes: 39.3;Horizontal cells: 18.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in all" 5 "cerebral cortex: 23.8;medulla oblongata: 30.7;pons: 47.8" "Immune cell enriched" "Detected in single" 116 "basophil: 94.9" "Lineage enriched" "Detected in single" 772 "granulocytes: 94.9" "Group enriched" "Detected in some" 8 "Leukemia: 9.0;Neuroblastoma: 17.4" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 5.4" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA 79000 "Cluster 46: Basophils - Proteolysis" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 6 "Vesicles, Cytosol" "CAB004606: AB_628397, CAB080140: , HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668375-85095751 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 241.7;thyroid gland: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 1085.3;Excitatory neurons: 725.3;Inhibitory neurons: 841.1;Oligodendrocyte precursor cells: 523.5" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.8;Esophageal cancer: 9.1" "Breast - Breast myoepithelial cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 2 "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256791 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7" "Cell type enhanced" "Detected in many" "Astrocytes: 227.0;Early spermatids: 123.1;Excitatory neurons: 348.4;Inhibitory neurons: 266.4;Late spermatids: 152.3;Microglial cells: 169.1;Oligodendrocyte precursor cells: 468.8" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 7.1;Neuroblastoma: 7.8;thyroid cancer: 5.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 10 "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 10.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.3;Excitatory neurons: 1.5;Inhibitory neurons: 1.2;Kupffer cells: 3.4;Undifferentiated cells: 1.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 6 "midbrain: 25.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.8;Gastric cancer: 13.5;pancreatic cancer: 19.5" "Kidney - Ascending Loop of Henle cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050299 Supported "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Bipolar cells - Visual perception" 1 "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 55.1;vagina: 43.9" "Cell type enhanced" "Detected in many" "Ductal cells: 44.0;Glandular and luminal cells: 51.0;Intestinal goblet cells: 47.2;Suprabasal keratinocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" NUDC ENSG00000090273 "Nuclear distribution C, dynein complex regulator" Q9Y266 1 26900238-26946871 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 750.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027183, HPA028105" Enhanced Enhanced Cytosol NA NA 140000 "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 43: Hepatocytes - Metabolism" 11 Cytosol "HPA027183: AB_10600086, HPA028105: AB_10601988" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.61e-2)" "unprognostic (6.52e-3)" "unprognostic (2.30e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-2)" "unprognostic (3.82e-1)" "unprognostic (3.26e-2)" "unprognostic (2.90e-2)" "unprognostic (1.55e-1)" "unprognostic (2.53e-1)" "unprognostic (5.10e-2)" NUP210 "FLJ22389, GP210, KIAA0906, POM210" ENSG00000132182 "Nucleoporin 210" Q8TEM1 3 13316235-13420322 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.5;lymphoid tissue: 31.7" "Cell type enhanced" "Detected in many" "dendritic cells: 67.3;Horizontal cells: 51.6;NK-cells: 54.2;Plasma cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Lung - T-cells, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066888 Approved NA NA 78000 "Cluster 30: Non-specific - DNA binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 "HPA066888: AB_2685741" "unprognostic (3.17e-2)" "unprognostic (2.09e-1)" "unprognostic (2.53e-1)" "unprognostic (3.60e-2)" "unprognostic (2.33e-1)" "unprognostic (9.72e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (1.96e-3)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-2)" "unprognostic (1.63e-2)" NUP210L ENSG00000143552 "Nucleoporin 210 like" Q5VU65 1 153992690-154155116 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 25.8" "Cell type enhanced" "Detected in some" "Early spermatids: 23.1;Excitatory neurons: 6.7;Inhibitory neurons: 8.0;Late spermatids: 8.3;Oligodendrocytes: 17.9;Spermatocytes: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047195, HPA064245, HPA066707" Enhanced Approved "Nuclear bodies" No No "Cluster 20: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Spermatocytes - Spermatogenesis" "Nuclear bodies" "HPA047195: AB_2679980, HPA064245: AB_2685224, HPA066707: AB_2685706" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (3.01e-1)" "unprognostic (1.80e-2)" "unprognostic (1.63e-2)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.79e-3)" "unprognostic (3.45e-2)" "unprognostic (5.57e-2)" "unprognostic (4.51e-4)" "unprognostic (1.15e-1)" "unprognostic (9.35e-10)" "unprognostic (4.20e-2)" "unprognostic (3.78e-2)" "unprognostic (7.45e-2)" "unprognostic (4.09e-2)" NUP88 MGC8530 ENSG00000108559 "Nucleoporin 88" Q99567 17 5359668-5420164 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 176.9;Oocytes: 86.0;Spermatocytes: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002209, HPA021816" Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 4: Testis - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 Nucleoplasm "CAB002209: AB_564128, HPA021816: AB_1854725" "unprognostic (3.46e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.83e-2)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-1)" "unprognostic (4.72e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-2)" "unprognostic (5.75e-3)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 112.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 38000 "Cluster 25: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 15: Non-specific - Mixed function" 6 "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" NXPE1 "FAM55A, MGC34290" ENSG00000095110 "Neurexophilin and PC-esterase domain family member 1" Q8N323 11 114518934-114559881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 72.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.5;Early spermatids: 88.3;Enteroendocrine cells: 19.3;Intestinal goblet cells: 53.3;Late spermatids: 50.3;Paneth cells: 22.6;Undifferentiated cells: 25.5" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" HPA049133 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 5 "HPA049133: AB_2680647" "unprognostic (2.81e-1)" "unprognostic (2.19e-3)" "unprognostic (3.40e-3)" "unprognostic (4.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (1.76e-1)" OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "choroid plexus: 28.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 29.8;Inhibitory neurons: 39.0;Melanocytes: 65.3;Oocytes: 15.4;Peritubular cells: 15.1" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Region enriched" "Detected in many" 10 "choroid plexus: 63.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "skin cancer: 24.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skin - Melanocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 30.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 103.4;Distal enterocytes: 84.8;Glandular and luminal cells: 119.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.6" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" OCSTAMP "C20orf123, dJ257E24.3" ENSG00000149635 "Osteoclast stimulatory transmembrane protein" Q9BR26 20 46540946-46550654 "Predicted membrane proteins, Transporters" Differentiation "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Myeloma: 4.7" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031116 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" "HPA031116: AB_10600758" "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (8.80e-2)" "unprognostic (5.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "unprognostic (9.59e-2)" "unprognostic (2.08e-1)" ODF4 "CT136, OPPO1" ENSG00000184650 "Outer dense fiber of sperm tails 4" Q2M2E3 17 8339840-8346048 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "testis: 12.7" "Group enriched" "Detected in some" 13 "Early spermatids: 40.3;Late spermatids: 31.8;Spermatocytes: 38.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA072129 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 18 "HPA072129: " "unprognostic (5.16e-2)" "unprognostic (5.13e-1)" "unprognostic (3.54e-4)" "unprognostic (3.64e-1)" "unprognostic (5.40e-2)" ODR4 "C1orf27, FLJ20505, odr-4, TTG1" ENSG00000157181 "Odr-4 GPCR localization factor homolog" Q5SWX8 1 186375838-186421378 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015988, HPA031352" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 75: Serous glandular cells - Salivary secretion" "Nucleoplasm, Plasma membrane" "HPA015988: AB_1845644, HPA031352: AB_2673838" "unprognostic (1.19e-2)" "unprognostic (4.23e-2)" "unprognostic (1.12e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" "unprognostic (8.57e-2)" "unprognostic (8.11e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.15e-2)" "unprognostic (9.85e-2)" "unprognostic (2.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (4.20e-2)" OGFOD3 "C17orf101, FLJ22222" ENSG00000181396 "2-oxoglutarate and iron dependent oxygenase domain containing 3" Q6PK18 17 82389210-82418637 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052099 Uncertain Approved Nucleoplasm NA NA 9700 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Plasma cells - Protein processing" Nucleoplasm "HPA052099: AB_2681725" "unprognostic (1.12e-2)" "unprognostic (5.85e-2)" "unprognostic (9.66e-2)" "unprognostic (9.69e-2)" "unprognostic (4.11e-3)" "unprognostic (2.09e-1)" "unprognostic (2.80e-2)" "unprognostic (1.99e-1)" "unprognostic (5.41e-2)" "unprognostic (7.15e-2)" "unprognostic (8.05e-3)" "unprognostic (2.95e-1)" "prognostic favorable (5.72e-4)" "unprognostic (7.43e-2)" "unprognostic (1.40e-1)" "unprognostic (7.08e-2)" "unprognostic (1.02e-1)" OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 97.0;placenta: 110.6" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 379.7;Hofbauer cells: 215.6;Langerhans cells: 114.6;Macrophages: 201.5;monocytes: 313.5;Syncytiotrophoblasts: 410.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 116.7;head and neck cancer: 80.2" "Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 1060000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Respiratory epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "HPA055120: AB_2682702" "prognostic favorable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favorable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527767-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol Nucleoplasm "HPA044881: AB_10964052" "unprognostic (3.37e-1)" "unprognostic (3.89e-2)" "unprognostic (2.66e-1)" "unprognostic (5.71e-3)" "unprognostic (1.24e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (3.14e-3)" "unprognostic (4.53e-2)" "unprognostic (8.06e-3)" "unprognostic (1.72e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.30e-12)" "unprognostic (5.85e-2)" "unprognostic (1.94e-1)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" OPALIN "HTMP10, TMEM10, TMP10" ENSG00000197430 "Oligodendrocytic myelin paranodal and inner loop protein" Q96PE5 10 96343221-96359365 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "brain: 138.8" "Cell type enriched" "Detected in some" 55 "Oligodendrocytes: 283.4" "Cancer enriched" "Detected in single" 36 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "white matter: 240.2" "Low region specificity" "Detected in all" HPA014372 Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" "HPA014372: AB_2158172" "unprognostic (1.18e-1)" OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 39.7" "Cell type enriched" "Detected in some" 20 "Cone photoreceptor cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Cytosol" "Cytokinetic bridge" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.1" "Cell type enhanced" "Detected in many" "dendritic cells: 210.0;Early spermatids: 161.5;Extravillous trophoblasts: 280.4;Langerhans cells: 251.8;Late spermatids: 106.7;Syncytiotrophoblasts: 155.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB013682, HPA064443" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" 1 Nucleoplasm "CAB013682: , HPA064443: AB_2685267" "unprognostic (2.41e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (1.75e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (7.12e-2)" "unprognostic (5.10e-3)" "unprognostic (1.24e-2)" "unprognostic (2.39e-1)" "unprognostic (4.96e-1)" "unprognostic (2.66e-2)" "unprognostic (3.44e-1)" "unprognostic (9.13e-2)" "unprognostic (9.15e-3)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (9.44e-3)" OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654518-86666460 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.9;brain: 2.8;skeletal muscle: 2.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Horizontal cells: 1.3;Inhibitory neurons: 1.8;Smooth muscle cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "HPA039147: AB_10673304" "unprognostic (3.67e-3)" "unprognostic (1.40e-2)" "unprognostic (3.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.03e-3)" "unprognostic (2.89e-2)" "unprognostic (3.26e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (8.88e-3)" "unprognostic (1.93e-6)" "unprognostic (4.10e-2)" "unprognostic (5.58e-2)" "unprognostic (6.76e-2)" OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.5" "Group enriched" "Detected in some" 12 "Early spermatids: 31.3;Late spermatids: 25.6;Spermatocytes: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" "HPA026084: AB_2671807" "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812170-28871267 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 11.4;Inhibitory neurons: 15.2" "Cancer enhanced" "Detected in single" "melanoma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.1;skin cancer: 4.4" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070831 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" 7 "HPA070831: AB_2732167" "unprognostic (1.44e-1)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-3)" "unprognostic (6.28e-3)" "unprognostic (5.92e-2)" "unprognostic (1.82e-2)" "unprognostic (5.95e-3)" "unprognostic (4.28e-3)" "unprognostic (2.98e-1)" "unprognostic (1.52e-7)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-3)" OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;prostate: 1.6;skeletal muscle: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.4;Extravillous trophoblasts: 9.2;Glandular and luminal cells: 8.6;Inhibitory neurons: 9.7;Leydig cells: 5.1;Prostatic glandular cells: 18.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;prostate cancer: 3.8" "Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" OPRM1 "MOP, MOR1" ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 36.1;Excitatory neurons: 39.8;Inhibitory neurons: 22.4;Late spermatids: 34.8;Microglial cells: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA014509: AB_1854801, HPA067435: " "unprognostic (7.34e-2)" "unprognostic (6.91e-2)" OR10A7 ENSG00000179919 "Olfactory receptor family 10 subfamily A member 7" Q8NGE5 12 55221025-55221975 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055111 Uncertain NA NA "HPA055111: AB_2682698" OR10AD1 OR10AD1P ENSG00000172640 "Olfactory receptor family 10 subfamily AD member 1" Q8NGE0 12 48202339-48203292 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 2.5" "Cell type enhanced" "Detected in single" "Oligodendrocyte precursor cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049913 Uncertain NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA049913: AB_2680950" "unprognostic (2.90e-1)" "unprognostic (2.79e-1)" "unprognostic (2.67e-2)" "unprognostic (1.70e-2)" "unprognostic (6.43e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (3.08e-2)" "unprognostic (1.74e-1)" OR10C1 "hs6M1-17, OR10C1P, OR10C2" ENSG00000206474 "Olfactory receptor family 10 subfamily C member 1" Q96KK4 6 29439306-29440977 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049336 Uncertain NA NA "HPA049336: AB_2680718" OR10G3 ENSG00000169208 "Olfactory receptor family 10 subfamily G member 3" Q8NGC4 14 21568520-21580076 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019766 Uncertain NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 21: Early spermatids - Spermatogenesis" "HPA019766: AB_1854780" OR10K1 ENSG00000173285 "Olfactory receptor family 10 subfamily K member 1" Q8NGX5 1 158461574-158470857 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Cholangiocytes: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059125 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "HPA059125: AB_2683913" OR10K2 ENSG00000180708 "Olfactory receptor family 10 subfamily K member 2" Q6IF99 1 158418210-158426237 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059125 Uncertain NA NA "HPA059125: AB_2683913" OR10P1 "OR10P1P, OR10P2P, OR10P3P, OST701" ENSG00000175398 "Olfactory receptor family 10 subfamily P member 1" Q8NGE3 12 55636892-55637833 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074114 Supported "Plasma membrane" NA NA "Cluster 50: Lymphoma - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA074114: " OR10Q1 ENSG00000180475 "Olfactory receptor family 10 subfamily Q member 1" Q8NGQ4 11 58227882-58228918 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046968 Uncertain NA NA "Cluster 15: Kidney cancer - Membrane components" "HPA046968: AB_2679881" "unprognostic (4.82e-1)" "unprognostic (6.34e-2)" "unprognostic (4.37e-1)" OR10R2 OR10R2Q ENSG00000198965 "Olfactory receptor family 10 subfamily R member 2" 1 158472220-158480936 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "Leukemia: 2.8" "Not detected" "Not detected" "HPA059775, HPA060399" Uncertain NA NA "Cluster 59: Leukemia - T-cell receptor" "HPA059775: AB_2684124, HPA060399: AB_2684276" OR10V1 ENSG00000172289 "Olfactory receptor family 10 subfamily V member 1" Q8NGI7 11 59712916-59713845 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Skin - Mast cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060076 Uncertain NA NA "HPA060076: AB_2684198" OR11H12 ENSG00000257115 "Olfactory receptor family 11 subfamily H member 12" B2RN74 14 18601117-18602097 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047370 Uncertain NA NA "HPA047370: AB_2680016" OR11H2 "C14orf15, OR11H2P, OR11H8P" ENSG00000258453 "Olfactory receptor family 11 subfamily H member 2" Q8NH07 14 19712904-19714332 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047370 Uncertain NA NA "HPA047370: AB_2680016" OR11H4 ENSG00000176198 "Olfactory receptor family 11 subfamily H member 4" 14 20239286-20244349 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052790 Uncertain NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 11: Late spermatids - Unknown function" "HPA052790: AB_2681950" OR13A1 ENSG00000256574 "Olfactory receptor family 13 subfamily A member 1" Q8NGR1 10 45302298-45315608 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "lymphoma: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA057237 Uncertain NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 13: Spermatids - Transcription" "HPA057237: AB_2683378" "unprognostic (7.88e-2)" "unprognostic (1.90e-1)" "unprognostic (5.52e-2)" "unprognostic (2.33e-5)" "unprognostic (6.43e-3)" "unprognostic (6.04e-2)" "unprognostic (8.65e-2)" "unprognostic (3.59e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.67e-15)" "unprognostic (6.54e-2)" "unprognostic (2.87e-1)" "unprognostic (8.55e-2)" "unprognostic (4.09e-3)" OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " "unprognostic (4.88e-2)" OR13C9 ENSG00000136839 "Olfactory receptor family 13 subfamily C member 9" Q8NGT0 9 104617248-104618204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " OR14A2 "OR5AX1, OR5AX1P" ENSG00000241128 "Olfactory receptor family 14 subfamily A member 2" Q96R54 1 247722957-247748141 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Cell type enriched" "Detected in some" 7 "Early spermatids: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA052685 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Early spermatids - Unknown function" "HPA052685: AB_2681914" OR14K1 OR5AY1 ENSG00000153230 "Olfactory receptor family 14 subfamily K member 1" Q8NGZ2 1 247738615-247739559 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA016643 Uncertain NA NA "Cluster 72: Neuronal - Signal transduction" "HPA016643: AB_1854788" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" OR1L3 OR9-D ENSG00000171481 "Olfactory receptor family 1 subfamily L member 3" Q8NH93 9 122675130-122676104 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058878 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "HPA058878: AB_2683843" OR1Q1 "HSTPCR106, OR1Q2, OR1Q3, OR9-A, OST226, OST226OR9-A, TPCR106" ENSG00000165202 "Olfactory receptor family 1 subfamily Q member 1" Q15612 9 122614738-122615682 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.1" "Cell type enriched" "Detected in single" 8 "Excitatory neurons: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044828 Uncertain NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "HPA044828: AB_10960565" "unprognostic (5.41e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" OR2A1 ENSG00000221970 "Olfactory receptor family 2 subfamily A member 1" Q8NGT9 7 144312419-144322737 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "thyroid gland: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA058272: AB_2683662" "unprognostic (3.98e-1)" "unprognostic (6.53e-2)" "unprognostic (1.13e-2)" "unprognostic (9.14e-2)" "unprognostic (2.22e-1)" OR2A25 "OR2A25P, OR2A27" ENSG00000221933 "Olfactory receptor family 2 subfamily A member 25" A4D2G3 7 144069811-144075870 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "NK-cells: 18.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 19: NK-cells - Adaptive immune response" "HPA058272: AB_2683662" OR2A4 OR2A10 ENSG00000180658 "Olfactory receptor family 2 subfamily A member 4" O95047 6 131699644-131701401 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "renal cancer: 0.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "basophil: 11.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.9" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Bone cancer - Neuronal signaling" "HPA058272: AB_2683662" "unprognostic (1.22e-5)" "unprognostic (3.60e-2)" OR2A42 ENSG00000212807 "Olfactory receptor family 2 subfamily A member 42" Q8NGT9 7 144228244-144239605 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Late spermatids - Unknown function" "HPA058272: AB_2683662" "unprognostic (1.41e-1)" "unprognostic (3.14e-1)" OR2A7 HSDJ0798C17 ENSG00000243896 "Olfactory receptor family 2 subfamily A member 7" Q96R45 7 144257663-144264792 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 12.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 12.2" "Low cancer specificity" "Detected in many" HPA058272 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Non-specific - Transcription" "HPA058272: AB_2683662" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (3.44e-2)" "unprognostic (2.57e-1)" "unprognostic (1.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.05e-1)" "unprognostic (4.13e-2)" "unprognostic (5.75e-2)" "unprognostic (7.28e-2)" "unprognostic (3.33e-1)" "unprognostic (9.08e-2)" "unprognostic (3.58e-3)" "unprognostic (5.52e-2)" "unprognostic (5.13e-2)" "unprognostic (3.06e-1)" "unprognostic (3.22e-1)" OR2AE1 OR2AE2 ENSG00000244623 "Olfactory receptor family 2 subfamily AE member 1" Q8NHA4 7 99876062-99877033 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042957 Uncertain NA NA "Cluster 80: Non-specific - Transcription" "HPA042957: AB_10794539" "unprognostic (6.75e-2)" "unprognostic (6.22e-2)" "unprognostic (5.21e-2)" "unprognostic (1.58e-1)" "unprognostic (3.16e-2)" OR2B11 ENSG00000177535 "Olfactory receptor family 2 subfamily B member 11" Q5JQS5 1 247449118-247458105 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "monocytes: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047459 Uncertain NA NA "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA047459: AB_10963692" "unprognostic (1.83e-1)" OR2C3 "OR2C4, OR2C5P, OST742" ENSG00000196242 "Olfactory receptor family 2 subfamily C member 3" Q8N628 1 247524677-247536440 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 4.1;granulocytes: 2.6;Late spermatids: 4.5;Spermatocytes: 5.6;Spermatogonia: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA058578 Supported "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA058578: AB_2683761" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.03e-1)" OR2D3 ENSG00000178358 "Olfactory receptor family 2 subfamily D member 3" Q8NGH3 11 6921002-6921994 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052551 Uncertain NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA052551: AB_2681867" "unprognostic (4.52e-1)" OR2K2 "HSHTPCRH06, HTPCRH06, OR2AR1P" ENSG00000171133 "Olfactory receptor family 2 subfamily K member 2" Q8NGT1 9 111327229-111330224 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA024261 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Oligodendrocytes - Unknown function" "HPA024261: AB_1854786" "unprognostic (1.03e-1)" OR2M4 "HSHTPCRX18, HTPCRX18, OST710, TPCR100" ENSG00000171180 "Olfactory receptor family 2 subfamily M member 4" Q96R27 1 248231417-248244679 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;Horizontal cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051308 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA051308: AB_2681435" OR2T10 ENSG00000184022 "Olfactory receptor family 2 subfamily T member 10" Q8NGZ9 1 248590487-248597700 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "kidney: 4.8" "Cell type enhanced" "Detected in some" "B-cells: 1.2;Oocytes: 5.1;Proximal tubular cells: 2.9" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052019 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 55: Lymphoma - Immune response" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA052019: AB_2681696" "unprognostic (8.58e-2)" OR2V1 "OR2V1P, OST265" ENSG00000185372 "Olfactory receptor family 2 subfamily V member 1" Q8NHB1 5 181123122-181131169 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 2.1;retina: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049953 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "HPA049953: AB_2680971" OR2V2 "OR2V3, OST713" ENSG00000182613 "Olfactory receptor family 2 subfamily V member 2" Q96R30 5 181147586-181159285 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049953 Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "HPA049953: AB_2680971" OR2W3 "OR2W3P, OR2W8P, OST718" ENSG00000238243 "Olfactory receptor family 2 subfamily W member 3" Q7Z3T1 1 247895587-247896531 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 12.8;thyroid gland: 6.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.6" "Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045594 Uncertain NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" "HPA045594: AB_10960280" "unprognostic (9.44e-2)" "unprognostic (3.03e-1)" "unprognostic (3.29e-2)" "unprognostic (1.57e-5)" "unprognostic (1.98e-1)" "unprognostic (5.11e-2)" "unprognostic (2.79e-6)" "unprognostic (2.71e-1)" "unprognostic (1.03e-1)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.71e-3)" "unprognostic (9.05e-3)" "unprognostic (9.34e-3)" "unprognostic (5.66e-2)" "unprognostic (1.48e-1)" OR2Z1 OR2Z2 ENSG00000181733 "Olfactory receptor family 2 subfamily Z member 1" Q8NG97 19 8721634-8732160 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048760 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA048760: AB_2680513" OR4A47 ENSG00000237388 "Olfactory receptor family 4 subfamily A member 47" Q6IF82 11 48488793-48489722 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059763 Uncertain NA NA "HPA059763: AB_2684122" OR4B1 OST208 ENSG00000175619 "Olfactory receptor family 4 subfamily B member 1" Q8NGF8 11 48216810-48217739 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059443 Uncertain NA NA "Cluster 58: Macrophages - Innate immune response" "HPA059443: AB_2684019" OR4C15 ENSG00000181939 "Olfactory receptor family 4 subfamily C member 15" Q8NGM1 11 55554307-55555419 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061939 Uncertain NA NA "HPA061939: AB_2684643" OR4C5 "OR4C5P, OR4C5Q" ENSG00000176540 "Olfactory receptor family 4 subfamily C member 5" Q8NGB2 11 48365485-48366465 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049516 Uncertain NA NA "HPA049516: AB_2680800" OR4D5 ENSG00000171014 "Olfactory receptor family 4 subfamily D member 5" Q8NGN0 11 123939617-123940573 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045005 Uncertain NA NA "HPA045005: AB_10959302" OR4F16 ENSG00000284662 "Olfactory receptor family 4 subfamily F member 16" Q6IEY1 1 685716-686654 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA 1 "HPA047705: AB_2680125" OR4F21 OR4F21P ENSG00000176269 "Olfactory receptor family 4 subfamily F member 21" O95013 8 166086-167024 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "HPA047705: AB_2680125" OR4F29 ENSG00000284733 "Olfactory receptor family 4 subfamily F member 29" Q6IEY1 1 450740-451678 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA 1 "HPA047705: AB_2680125" OR4F3 ENSG00000230178 "Olfactory receptor family 4 subfamily F member 3" Q6IEY1 5 181367268-181368262 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" 1 "HPA047705: AB_2680125" OR4K1 ENSG00000155249 "Olfactory receptor family 4 subfamily K member 1" Q8NGD4 14 19930917-19936757 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028877 Uncertain NA NA "Cluster 47: Leukemia - Hemostasis" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA028877: AB_10600923" OR4K15 OR4K15Q ENSG00000169488 "Olfactory receptor family 4 subfamily K member 15" Q8NH41 14 19975591-19976565 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055732 Uncertain NA NA "HPA055732: AB_2682900" OR4M1 ENSG00000176299 "Olfactory receptor family 4 subfamily M member 1" Q8NGD0 14 19773504-19783696 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Early spermatids: 65.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 18: Early spermatids - Unknown function" "HPA058889: AB_2683845" OR4M2 ENSG00000274102 "Olfactory receptor family 4 subfamily M member 2" Q8NGB6 15 22070241-22083221 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 50 "Early spermatids: 54.2;Late spermatids: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 18: Early spermatids - Unknown function" "HPA058889: AB_2683845" OR4M2-OT1 ENSG00000285472 "OR4M2 overlapping transcript 1" 15 22015233-22095857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 48 "testis: 4.8" "Group enriched" "Detected in some" 11 "Early spermatids: 18.5;Late spermatids: 8.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Approved Centrosome NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" Centrosome "HPA057442: AB_2683442" OR4M2B ENSG00000182974 "Olfactory receptor family 4 subfamily M member 2B" A0A0X1KG70 15 21637909-21638992 "Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 13 "Early spermatids: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA058889: AB_2683845" OR4N4 ENSG00000183706 "Olfactory receptor family 4 subfamily N member 4" Q8N0Y3 15 22094522-22095862 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 78 "testis: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Uncertain Centrosome NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" Centrosome "HPA057442: AB_2683442" OR4N4C ENSG00000279408 "Olfactory receptor family 4 subfamily N member 4C" A0A096LPK9 15 21651844-21652968 "Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA057442 Uncertain Uncertain Centrosome NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" Centrosome "HPA057442: AB_2683442" OR4P4 OR4P3P ENSG00000181927 "Olfactory receptor family 4 subfamily P member 4" Q8NGL7 11 55635113-55640309 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059458 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "HPA059458: AB_2684027" OR4Q3 "C14orf13, OR4Q4" ENSG00000182652 "Olfactory receptor family 4 subfamily Q member 3" 14 19743571-19749469 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049924 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA049924: AB_2680955" OR51A7 ENSG00000176895 "Olfactory receptor family 51 subfamily A member 7" Q8NH64 11 4903783-4909462 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061356 Uncertain NA NA "Cluster 18: Early spermatids - Unknown function" "HPA061356: AB_2684488" "unprognostic (4.57e-1)" OR51B5 ENSG00000167355 "Olfactory receptor family 51 subfamily B member 5" Q9H339 11 5303444-5505652 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Oocytes: 83.1" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063124 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" "HPA063124: AB_2684943" "unprognostic (9.22e-3)" "unprognostic (1.80e-1)" "unprognostic (2.01e-1)" "unprognostic (3.76e-2)" "unprognostic (4.75e-1)" "unprognostic (1.36e-1)" "unprognostic (7.37e-5)" "unprognostic (2.94e-1)" "unprognostic (2.43e-1)" "unprognostic (4.20e-2)" "unprognostic (2.71e-2)" OR51D1 OR51D1Q ENSG00000197428 "Olfactory receptor family 51 subfamily D member 1" Q8NGF3 11 4637477-4643060 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bipolar cells: 2.2;Horizontal cells: 2.5;Oocytes: 1.5;Prostatic glandular cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061240 Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" "HPA061240: AB_2684457" "unprognostic (1.90e-1)" OR51E1 "GPR136, GPR164, OR51E1P, OR52A3P" ENSG00000180785 "Olfactory receptor family 51 subfamily E member 1" Q8TCB6 11 4643420-4655488 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.5;placenta: 7.2;prostate: 6.4" "Cell type enhanced" "Detected in some" "Adipocytes: 36.1;Enteroendocrine cells: 41.7;Prostatic glandular cells: 110.5;Sertoli cells: 13.6;Smooth muscle cells: 20.5" "Cancer enriched" "Detected in many" 21 "prostate cancer: 34.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 1.8;lung cancer: 2.5;prostate cancer: 7.0;thyroid cancer: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB019995, HPA051439" Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "CAB019995: AB_10283600, HPA051439: AB_2681487" "unprognostic (6.67e-3)" "unprognostic (2.34e-3)" "unprognostic (9.71e-2)" "unprognostic (4.87e-5)" "unprognostic (3.55e-2)" "unprognostic (9.80e-3)" "unprognostic (1.76e-1)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.94e-3)" "unprognostic (7.36e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.23e-6)" "unprognostic (2.72e-3)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.86e-1)" OR51M1 ENSG00000184698 "Olfactory receptor family 51 subfamily M member 1" Q9H341 11 5383812-5393263 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Oocytes: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056773 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" "HPA056773: AB_2683233" OR51Q1 ENSG00000167360 "Olfactory receptor family 51 subfamily Q member 1" Q8NH59 11 5422111-5423206 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "olfactory bulb: 4.9" HPA044998 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "HPA044998: AB_10794780" OR51T1 ENSG00000176900 "Olfactory receptor family 51 subfamily T member 1" Q8NGJ9 11 4881819-4882883 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046877 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA046877: AB_2679853" "unprognostic (2.59e-1)" OR52D1 ENSG00000181609 "Olfactory receptor family 52 subfamily D member 1" Q9H346 11 5488685-5489749 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "olfactory bulb: 4.2" HPA046965 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "HPA046965: AB_2679878" OR52E2 ENSG00000176787 "Olfactory receptor family 52 subfamily E member 2" Q8NGJ4 11 5058650-5059627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045748 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA045748: AB_10959665" OR52N1 ENSG00000181001 "Olfactory receptor family 52 subfamily N member 1" Q8NH53 11 5786471-5791265 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.4;Lymphatic endothelial cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054028 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA054028: AB_2682348" OR56B1 OR56B1P ENSG00000181023 "Olfactory receptor family 56 subfamily B member 1" Q8NGI3 11 5736448-5738523 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045043 Uncertain NA NA "Cluster 73: B-cells - B-cell function" "HPA045043: AB_10794296" OR5A2 ENSG00000172324 "Olfactory receptor family 5 subfamily A member 2" Q8NGI9 11 59416969-59426413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in single" "dendritic cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047135, HPA049575" Uncertain NA NA "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 11: Late spermatids - Unknown function" "HPA047135: AB_2679948, HPA049575: AB_2680820" OR5D16 ENSG00000205029 "Olfactory receptor family 5 subfamily D member 16" Q8NGK9 11 55838752-55839738 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046711 Uncertain NA NA "HPA046711: AB_2679766" OR5F1 OR11-10 ENSG00000149133 "Olfactory receptor family 5 subfamily F member 1" O95221 11 55993681-55994625 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059360 Uncertain NA NA "HPA059360: AB_2683990" OR5J2 ENSG00000174957 "Olfactory receptor family 5 subfamily J member 2" Q8NH18 11 56176618-56177556 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059466 Uncertain NA NA "Cluster 69: Skin cancer - ECM organization" "HPA059466: AB_2684029" OR5L1 OST262 ENSG00000279395 "Olfactory receptor family 5 subfamily L member 1" Q8NGL2 11 55811367-55812476 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047524 Uncertain NA NA "HPA047524: AB_2680076" OR5L2 "HSHTPCRX16, HTPCRX16" ENSG00000205030 "Olfactory receptor family 5 subfamily L member 2" Q8NGL0 11 55827219-55828154 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047524 Uncertain NA NA "HPA047524: AB_2680076" OR5P3 JCG1 ENSG00000182334 "Olfactory receptor family 5 subfamily P member 3" Q8WZ94 11 7824818-7830840 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Rod photoreceptor cells: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060787 Uncertain NA NA "Cluster 66: Photoreceptor cells - Visual perception" "HPA060787: AB_2684364" "unprognostic (1.54e-1)" OR5T1 OR5T1P ENSG00000181698 "Olfactory receptor family 5 subfamily T member 1" Q8NG75 11 56274154-56276819 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA050952 Uncertain NA NA "HPA050952: AB_2681287" OR5V1 hs6M1-21 ENSG00000243729 "Olfactory receptor family 5 subfamily V member 1" Q9UGF6 6 29353749-29431967 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Early spermatids: 15.6;Late spermatids: 14.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA046707 Uncertain NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 11: Late spermatids - Unknown function" "HPA046707: AB_2679763" OR6B1 OR7-3 ENSG00000221813 "Olfactory receptor family 6 subfamily B member 1" O95007 7 144000320-144008793 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA053164 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA053164: AB_2682065" OR6B2 OR6B2P ENSG00000182083 "Olfactory receptor family 6 subfamily B member 2" Q6IFH4 2 240029491-240030429 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA047529: AB_2680077" OR6B3 "OR6B3P, OR6B3Q" ENSG00000178586 "Olfactory receptor family 6 subfamily B member 3" Q8NGW1 2 240044571-240053521 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 20 "retina: 20.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 76: Retina - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" Cytosol "HPA047529: AB_2680077" OR6C6 ENSG00000188324 "Olfactory receptor family 6 subfamily C member 6" A6NF89 12 55293988-55296569 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051090 Uncertain Approved "Lipid droplets,Plasma membrane" NA NA "Cluster 48: Non-specific - Mixed function" "Lipid droplets, Plasma membrane" "HPA051090: AB_2681341" OR6K3 ENSG00000203757 "Olfactory receptor family 6 subfamily K member 3" Q8NGY3 1 158716327-158720720 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "bone marrow: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "basophil: 8.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.2" "Not detected" "Not detected" HPA055949 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "HPA055949: AB_2682982" OR6M1 ENSG00000196099 "Olfactory receptor family 6 subfamily M member 1" Q8NGM8 11 123805408-123806349 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048674 Uncertain NA NA "Cluster 30: Non-specific - Gene expression regulation" "Cluster 21: Early spermatids - Spermatogenesis" "HPA048674: AB_2680489" OR6N2 ENSG00000188340 "Olfactory receptor family 6 subfamily N member 2" Q8NGY6 1 158774222-158781204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "bone marrow: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056637 Uncertain NA NA "Cluster 6: Bone marrow - Innate immune response" "HPA056637: AB_2683198" OR6P1 ENSG00000186440 "Olfactory receptor family 6 subfamily P member 1" Q8NGX9 1 158560606-158570580 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047466 Uncertain NA NA "Cluster 11: Late spermatids - Unknown function" "HPA047466: AB_10963091" OR6T1 ENSG00000181499 "Olfactory receptor family 6 subfamily T member 1" Q8NGN1 11 123942867-123943838 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060893 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "HPA060893: AB_2684380" "unprognostic (9.30e-4)" OR7A5 HTPCR2 ENSG00000188269 "Olfactory receptor family 7 subfamily A member 5" Q15622 19 14826241-14835185 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.2;epididymis: 4.4;parathyroid gland: 6.8" "Cell type enriched" "Detected in single" 9 "Melanocytes: 6.9" "Cancer enriched" "Detected in single" 8 "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate basal glandular cells" HPA053823 Uncertain NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA053823: AB_2682274" "unprognostic (3.26e-4)" "unprognostic (1.44e-1)" "unprognostic (7.46e-2)" "unprognostic (6.19e-3)" "unprognostic (4.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (6.78e-2)" "unprognostic (2.01e-7)" "unprognostic (6.45e-2)" "unprognostic (9.64e-2)" "unprognostic (6.44e-2)" "unprognostic (2.47e-3)" OR7C1 "OR19-5, OR7C4" ENSG00000127530 "Olfactory receptor family 7 subfamily C member 1" O76099 19 14789260-14835376 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "parathyroid gland: 6.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 15.4;Melanocytes: 8.6;Prostatic glandular cells: 5.0" "Cancer enriched" "Detected in single" 9 "melanoma: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.2" "Not detected" "Not detected" HPA047127 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA047127: AB_2679944" "unprognostic (7.68e-4)" "unprognostic (1.31e-1)" "unprognostic (2.13e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.39e-1)" "unprognostic (4.30e-2)" "unprognostic (6.11e-4)" "unprognostic (1.90e-1)" "unprognostic (6.80e-2)" "unprognostic (6.91e-2)" OR7C2 "OR19-18, OR7C3" ENSG00000127529 "Olfactory receptor family 7 subfamily C member 2" O60412 19 14941489-14942448 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047295 Uncertain NA NA 1 "HPA047295: AB_2680013" OR8D1 "OR8D3, OST004" ENSG00000196341 "Olfactory receptor family 8 subfamily D member 1" Q8WZ84 11 124302831-124315099 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059510 Uncertain NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 18: Early spermatids - Unknown function" "HPA059510: AB_2684045" OR8K1 ENSG00000150261 "Olfactory receptor family 8 subfamily K member 1" Q8NGG5 11 56346039-56346998 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055233 Uncertain NA NA "HPA055233: AB_2682749" OR9K2 ENSG00000170605 "Olfactory receptor family 9 subfamily K member 2" 12 55126406-55132750 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015808 Uncertain NA NA "HPA015808: AB_2669306" ORAI1 "CRACM1, FLJ14466, TMEM142A" ENSG00000276045 "ORAI calcium release-activated calcium modulator 1" Q96D31 12 121626509-121643218 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 65.0;skeletal muscle: 58.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 72.1;NK-cells: 120.8;T-cells: 70.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 41.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016583 Approved NA NA "Cluster 27: T-cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "HPA016583: AB_1848720" "unprognostic (2.22e-2)" "unprognostic (3.78e-3)" "unprognostic (7.82e-3)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (1.99e-3)" "unprognostic (4.25e-3)" "unprognostic (1.92e-1)" "unprognostic (2.00e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "unprognostic (6.84e-2)" "unprognostic (1.95e-1)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" ORAI2 "C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B" ENSG00000160991 "ORAI calcium release-activated calcium modulator 2" Q96SN7 7 102433106-102456825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 37.9" "Cell type enhanced" "Detected in many" "B-cells: 114.7;Glandular and luminal cells: 68.2;Plasma cells: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.0;eosinophil: 24.9;memory B-cell: 10.2;naive B-cell: 11.4;neutrophil: 27.7;NK-cell: 8.3" "Group enriched" "Detected in all" 5 "B-cells: 11.4;granulocytes: 27.7;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055137, HPA065937" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 73: B-cells - B-cell function" Nucleoplasm "HPA055137: AB_2682712, HPA065937: AB_2685581" "unprognostic (5.09e-3)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (5.07e-3)" "unprognostic (8.56e-2)" "unprognostic (3.82e-2)" "unprognostic (7.07e-2)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.49e-5)" "unprognostic (7.16e-2)" "unprognostic (1.57e-3)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "prognostic favorable (6.65e-4)" "unprognostic (2.46e-1)" ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 50: Connective tissue cells - ECM organization" 1 "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" ORC3 "IMAGE50150, LATHEO, ORC3L" ENSG00000135336 "Origin recognition complex subunit 3" Q9UBD5 6 87590067-87667453 "Predicted intracellular proteins, Predicted membrane proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039553, HPA053748" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 5 Nucleoplasm "HPA039553: AB_2676566, HPA053748: AB_2682247" "unprognostic (9.38e-3)" "unprognostic (2.38e-1)" "unprognostic (3.74e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (8.63e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (2.26e-3)" "unprognostic (1.21e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "unprognostic (3.38e-3)" "unprognostic (1.09e-1)" ORMDL1 ENSG00000128699 "ORMDL sphingolipid biosynthesis regulator 1" Q9P0S3 2 189770267-189784364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Spleen - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 24: Cytotrophoblasts - Mitochondria" 31 "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.45e-1)" "unprognostic (5.34e-3)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-3)" "unprognostic (1.86e-2)" "unprognostic (6.70e-3)" "prognostic favorable (3.04e-5)" "unprognostic (5.90e-3)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.84e-9)" "unprognostic (2.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "prognostic favorable (1.49e-5)" ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 18 "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 228.8" "Cell type enhanced" "Detected in many" "Early spermatids: 221.6;Late spermatids: 374.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 23 "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "HPA038335: AB_2675963, HPA038712: AB_10675949, HPA058727: AB_2683799" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (3.69e-2)" "unprognostic (8.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-3)" "unprognostic (9.44e-2)" "unprognostic (2.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 13.2;lung: 27.5;lymphoid tissue: 29.0" "Group enriched" "Detected in some" 5 "Hofbauer cells: 49.4;Kupffer cells: 23.7;Langerhans cells: 16.0;Macrophages: 41.3;monocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 35 "classical monocyte: 41.9;eosinophil: 26.4;intermediate monocyte: 28.1;myeloid DC: 19.6;neutrophil: 38.8;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 77 "dendritic cells: 19.6;granulocytes: 38.8;monocytes: 41.9" "Group enriched" "Detected in some" 4 "Leukemia: 8.2;ovarian cancer: 2.5;thyroid cancer: 5.9" "Adipose subcutaneous - Macrophages, Kidney - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 84000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" OSMR "OSMRB, OSMRbeta" ENSG00000145623 "Oncostatin M receptor" Q99650 5 38845858-38945596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 113.9;Alveolar cells type 2: 68.3;Endothelial cells: 68.6;Mucus glandular cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017278 Approved Approved Nucleoli "Intracellular and membrane" Receptor NA NA 51000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 9 Nucleoli "HPA017278: AB_1854818" "unprognostic (6.34e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.58e-1)" "unprognostic (2.11e-1)" "unprognostic (2.18e-3)" "unprognostic (1.13e-1)" "unprognostic (8.00e-3)" "unprognostic (5.70e-2)" "unprognostic (1.79e-3)" "unprognostic (1.72e-3)" "unprognostic (1.60e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.96e-6)" "unprognostic (1.88e-2)" "unprognostic (1.49e-2)" "unprognostic (4.43e-1)" "unprognostic (1.75e-2)" OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108029245-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Melanocytes: 202.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 1 Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" OTOF "DFNB6, DFNB9, FER1L2" ENSG00000115155 Otoferlin Q9HC10 2 26457203-26558756 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.4;brain: 21.0" "Cell type enriched" "Detected in single" 4 "Inhibitory neurons: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;lymphoma: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012410 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 69: Neurons - Neuronal signaling" "HPA012410: AB_1854836" "unprognostic (4.01e-3)" "unprognostic (7.85e-2)" "unprognostic (8.95e-2)" "unprognostic (7.20e-5)" "unprognostic (1.82e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (6.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.26e-1)" "unprognostic (2.97e-3)" "unprognostic (4.85e-14)" "unprognostic (1.33e-2)" "unprognostic (5.19e-1)" "unprognostic (9.65e-2)" "unprognostic (8.96e-5)" OTOP1 ENSG00000163982 "Otopetrin 1" Q7RTM1 4 4188726-4226929 "Predicted membrane proteins, Transporters" "Biomineralization, Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA035599 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" "Cluster 36: Late spermatids - Unknown function" "HPA035599: AB_10600924" "unprognostic (1.83e-1)" "unprognostic (1.09e-1)" OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 19.4" "Cell type enriched" "Detected in some" 29 "Paneth cells: 1021.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.0" "Colon - Colon enterocytes, Testis - Late spermatids" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in all" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 5: Enterocytes - Absorption" 4 "Plasma membrane" "HPA024524: AB_2671592, HPA053090: AB_2682041" "unprognostic (1.62e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (3.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (9.04e-2)" "unprognostic (2.04e-2)" OTULINL "FAM105A, FLJ11127, NET20" ENSG00000145569 "OTU deubiquitinase with linear linkage specificity like" Q9NUU6 5 14581792-14616180 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 178.1;dendritic cells: 180.5;Hofbauer cells: 104.0;Langerhans cells: 90.9;Spermatocytes: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046638 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 11 "Nucleoli, Cytosol" "HPA046638: AB_2679731" "unprognostic (1.47e-1)" "unprognostic (6.64e-3)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (6.26e-2)" "unprognostic (1.13e-3)" "unprognostic (2.33e-2)" "unprognostic (2.27e-2)" "unprognostic (6.44e-2)" "unprognostic (2.42e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.13e-1)" "unprognostic (1.33e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (3.14e-1)" "unprognostic (8.79e-3)" OXA1L "MGC133129, OXA1, OXA1L1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA003531: AB_1079539" "unprognostic (4.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (7.25e-2)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "prognostic favorable (4.82e-4)" "unprognostic (8.35e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (1.15e-3)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762499-42764135 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 55.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 6.4;Melanocytes: 5.2;Paneth cells: 5.2;Proximal enterocytes: 13.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 73.5;eosinophil: 158.2" "Lineage enriched" "Detected in many" 81 "granulocytes: 158.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" HPA051433 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 29 "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985713-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.9;Rhabdoid: 5.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;pancreas: 63.1;urinary bladder: 73.0" "Cell type enhanced" "Detected in some" "dendritic cells: 48.3;Erythroid cells: 16.5;granulocytes: 67.4;monocytes: 72.6;Plasma cells: 39.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.5" "Group enriched" "Detected in many" 30 "dendritic cells: 15.2;granulocytes: 23.6;monocytes: 46.5" "Group enriched" "Detected in some" 9 "Leukemia: 14.1;Myeloma: 15.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skin - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.8" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 57: Platelets - Hemostasis" 1 "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" P2RX3 P2X3 ENSG00000109991 "Purinergic receptor P2X 3" P56373 11 57338352-57372396 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.8;liver: 1.7;testis: 4.6" "Group enriched" "Detected in some" 6 "Early spermatids: 28.0;Late spermatids: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 24.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057776 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" "HPA057776: AB_2683526" "unprognostic (5.44e-2)" "unprognostic (9.43e-2)" "unprognostic (2.84e-1)" "unprognostic (1.33e-3)" "unprognostic (2.24e-2)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-7)" "unprognostic (1.58e-1)" "unprognostic (2.88e-1)" "unprognostic (3.00e-2)" "unprognostic (1.29e-1)" P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121210065-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.4;Hofbauer cells: 118.5;Intestinal goblet cells: 100.8;Proximal enterocytes: 94.8;Syncytiotrophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 6 "HPA039494: AB_10969132" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" "unprognostic (5.43e-2)" "prognostic favorable (6.30e-10)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (7.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.13e-1)" "unprognostic (6.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.76e-3)" P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.0;lymphoid tissue: 77.2" "Group enriched" "Detected in some" 4 "B-cells: 114.0;Plasma cells: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.8;naive B-cell: 85.6" "Lineage enriched" "Detected in many" 20 "B-cells: 85.6" "Cancer enhanced" "Detected in many" "lymphoma: 68.0" "Breast - Plasma cells, Lung - B-cells, Thyroid - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021948, HPA067827" Supported Supported Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 Cytosol "HPA021948: AB_1854878, HPA067827: AB_2685908" "unprognostic (1.08e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (4.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.99e-8)" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (3.50e-2)" "unprognostic (3.63e-2)" P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028013 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 25.1;tongue: 11.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Excitatory neurons: 8.6;Horizontal cells: 10.7;Inhibitory neurons: 7.6;Oligodendrocyte precursor cells: 4.7;Skeletal myocytes: 5.9" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.3" "Liver - Hepatic stellate cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.0;Langerhans cells: 82.3;Melanocytes: 48.1;Oligodendrocyte precursor cells: 82.5;Oligodendrocytes: 145.9" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Myeloma: 15.3;skin cancer: 12.8" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" 10 "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 24.6" "Cell type enhanced" "Detected in many" "monocytes: 91.9;Prostatic glandular cells: 61.5;Squamous epithelial cells: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.7" "Cancer enhanced" "Detected in many" "cervical cancer: 9.6;Gallbladder cancer: 11.3" "Adipose subcutaneous - Macrophages, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015577 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 33: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 1 "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in some" "B-cells: 110.4;Langerhans cells: 73.3;NK-cells: 27.0;Plasma cells: 37.8;Schwann cells: 37.7;T-cells: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 256.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 4.9;lymphoma: 14.7;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036757, HPA065766" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" P2RY11 P2Y11 ENSG00000244165 "Purinergic receptor P2Y11" Q96G91 19 10111693-10115372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.1;NK-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.9" "Group enriched" "Detected in many" 5 "NK-cells: 13.9;T-cells: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014232 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" "HPA014232: AB_1854883" "unprognostic (1.13e-1)" "unprognostic (3.12e-2)" "unprognostic (2.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (2.34e-1)" "unprognostic (5.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.04e-3)" "unprognostic (2.22e-2)" "unprognostic (4.32e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.77e-4)" P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 43.4" "Cell type enriched" "Detected in some" 12 "Microglial cells: 402.6" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 3.0" "Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA013796: AB_1854884, HPA014518: AB_2669027" "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 23.8;Kupffer cells: 95.4;Macrophages: 56.3;Microglial cells: 63.5;monocytes: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 583.2" "Group enriched" "Detected in many" 6 "granulocytes: 583.2;monocytes: 186.3" "Not detected" "Not detected" "Kidney - Macrophages, Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" P2RY14 "GPR105, KIAA0001" ENSG00000174944 "Purinergic receptor P2Y14" Q15391 3 151212117-151278542 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.6" "Cell type enhanced" "Detected in some" "dendritic cells: 205.0;Endometrial stromal cells: 46.1;Excitatory neurons: 39.9;granulocytes: 44.3;Langerhans cells: 71.3;Schwann cells: 43.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 57.6" "Group enriched" "Detected in many" 9 "eosinophil: 230.9;plasmacytoid DC: 98.2" "Group enriched" "Detected in many" 9 "dendritic cells: 98.2;granulocytes: 230.9" "Cancer enhanced" "Detected in some" "Leukemia: 1.6;Rhabdoid: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022646 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "CAB022646: " "unprognostic (9.78e-2)" "unprognostic (7.47e-4)" "unprognostic (3.89e-2)" "unprognostic (4.52e-4)" "unprognostic (1.69e-2)" "unprognostic (2.57e-5)" "unprognostic (2.68e-2)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (1.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.72e-5)" "unprognostic (3.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-2)" P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.9;skeletal muscle: 48.4;tongue: 29.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.3;Proximal enterocytes: 15.0;Squamous epithelial cells: 15.4;Suprabasal keratinocytes: 13.7;Syncytiotrophoblasts: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.7" "Group enriched" "Detected in many" 12 "granulocytes: 57.7;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" P2RY4 "NRU, P2P, P2Y4, UNR" ENSG00000186912 "Pyrimidinergic receptor P2Y4" P51582 X 70258166-70260204 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 2.1" "Cell type enriched" "Detected in single" 8 "Intestinal goblet cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022644 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "CAB022644: " "unprognostic (4.59e-2)" "unprognostic (4.23e-1)" "unprognostic (7.10e-2)" "unprognostic (1.69e-1)" "unprognostic (9.53e-4)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (6.77e-2)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.90e-2)" "unprognostic (3.72e-2)" "unprognostic (3.61e-2)" "unprognostic (1.50e-2)" "unprognostic (3.89e-1)" P2RY6 P2Y6 ENSG00000171631 "Pyrimidinergic receptor P2Y6" Q15077 11 73264498-73305103 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.7" "Group enriched" "Detected in many" 12 "Cytotrophoblasts: 163.4;dendritic cells: 509.0;Syncytiotrophoblasts: 371.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "myeloid DC: 27.2;plasmacytoid DC: 87.6" "Lineage enriched" "Detected in many" 19 "dendritic cells: 87.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074751 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" 15 "HPA074751: " "unprognostic (2.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.04e-2)" "unprognostic (5.54e-3)" "unprognostic (4.18e-3)" "unprognostic (1.94e-2)" "unprognostic (3.93e-3)" "unprognostic (4.00e-3)" "unprognostic (1.86e-4)" "unprognostic (3.08e-1)" "unprognostic (1.25e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (2.50e-7)" "unprognostic (1.48e-2)" "unprognostic (1.38e-3)" "unprognostic (7.67e-2)" "unprognostic (1.05e-1)" P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 30.8;lymphoid tissue: 39.1" "Cell type enhanced" "Detected in some" "B-cells: 41.6;NK-cells: 71.0;Plasma cells: 33.7;T-cells: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 20 "Leukemia: 63.3;lymphoma: 94.3;Myeloma: 49.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - T-cells" "Low region specificity" "Detected in many" HPA003631 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" P4HTM "EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4" ENSG00000178467 "Prolyl 4-hydroxylase, transmembrane" Q9NXG6 3 48989889-49007153 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 165.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 186.2;Late spermatids: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007199 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" "Vesicles, Cytosol" "HPA007199: AB_1855272" "unprognostic (1.95e-2)" "unprognostic (3.12e-2)" "unprognostic (9.47e-2)" "prognostic favorable (8.18e-4)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-2)" "prognostic favorable (3.28e-5)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (2.60e-2)" "unprognostic (9.65e-3)" PAAF1 "FLJ11848, Rpn14, WDR71" ENSG00000175575 "Proteasomal ATPase associated factor 1" Q9BRP4 11 73876699-73931114 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 106.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA039952, HPA040020" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 25: Bipolar cells - Visual perception" 3 Nucleoplasm Cytosol "HPA039952: AB_10793925, HPA040020: AB_2676802" "unprognostic (3.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.13e-2)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (1.74e-1)" "unprognostic (4.48e-1)" "unprognostic (2.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (2.73e-1)" "unprognostic (4.42e-1)" PABIR3 "FAM122C, RP3-473B4.1" ENSG00000156500 "PABIR family member 3" Q6P4D5 X 134796395-134854835 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 79.9;Granulosa cells: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059961 Approved Uncertain Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Early spermatids - Unknown function" Nucleoplasm "HPA059961: AB_2684181" "unprognostic (1.32e-2)" "unprognostic (3.50e-2)" "unprognostic (7.63e-2)" "unprognostic (3.38e-3)" "unprognostic (1.08e-1)" "unprognostic (5.25e-2)" "unprognostic (1.85e-1)" "unprognostic (3.76e-3)" "unprognostic (3.50e-2)" "unprognostic (7.20e-3)" "unprognostic (2.28e-1)" "unprognostic (1.03e-2)" "unprognostic (2.41e-2)" "unprognostic (5.93e-2)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" "unprognostic (4.16e-3)" PACC1 "ASOR, C1orf75, FLJ10874, PAC, PAORAC, TMEM206" ENSG00000065600 "Proton activated chloride channel 1" Q9H813 1 212363928-212414901 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 70.7" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 31.6;Oligodendrocytes: 59.2;Oocytes: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008540 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 14: Langerhans cells - Innate immune response" 5 "HPA008540: AB_10794083" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (9.23e-2)" "unprognostic (1.02e-1)" "unprognostic (2.74e-2)" "unprognostic (3.09e-2)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.06e-3)" "unprognostic (6.33e-2)" "unprognostic (1.02e-1)" "unprognostic (9.10e-2)" "unprognostic (6.98e-2)" PACRG "FLJ32724, Glup, HAK005771, PARK2CRG" ENSG00000112530 "Parkin coregulated" Q96M98 6 162727132-163315500 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.4;testis: 27.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 114.7;Early spermatids: 307.8;Excitatory neurons: 120.0;Inhibitory neurons: 167.4;Late spermatids: 388.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066293 Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" "HPA066293: AB_2685652" "unprognostic (3.06e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (1.84e-1)" "unprognostic (6.26e-4)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.34e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (8.35e-2)" "unprognostic (2.93e-3)" PALD1 "KIAA1274, PALD" ENSG00000107719 "Phosphatase domain containing paladin 1" Q9ULE6 10 70478767-70668754 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 42.4;Lymphatic endothelial cells: 39.1;Macrophages: 17.8;Microglial cells: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015696, HPA017343" Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "HPA015696: AB_1852399, HPA017343: AB_1852397" "unprognostic (1.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-1)" "unprognostic (7.94e-2)" "unprognostic (2.52e-3)" "unprognostic (4.52e-3)" "unprognostic (3.55e-2)" "unprognostic (4.96e-2)" "unprognostic (3.34e-2)" "unprognostic (6.56e-2)" "unprognostic (2.48e-1)" "unprognostic (8.20e-3)" "unprognostic (2.73e-2)" "unprognostic (9.27e-2)" "unprognostic (2.46e-1)" "unprognostic (8.81e-3)" PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103029730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1508.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1260.5;Excitatory neurons: 221.7;Inhibitory neurons: 468.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" Enzyme NA NA 98000000 "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.0;Extravillous trophoblasts: 36.1;Suprabasal keratinocytes: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 13 "Plasma membrane" "HPA016930: AB_1854954" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.09e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-3)" PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 39.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 12.9;dendritic cells: 12.9;Excitatory neurons: 12.9;Horizontal cells: 13.2;Inhibitory neurons: 15.1;Muller glia cells: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.0" "Lineage enhanced" "Detected in single" "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Plasma membrane" "HPA004624: , HPA039117: AB_10805354" "unprognostic (1.00e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-9)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.00e-1)" "unprognostic (4.08e-1)" PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567116 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 812.7;Syncytiotrophoblasts: 1032.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Nucleoplasm "HPA001788: AB_1079564" "unprognostic (3.18e-1)" "unprognostic (1.30e-1)" "unprognostic (9.69e-2)" "unprognostic (7.26e-2)" "unprognostic (9.10e-2)" "unprognostic (5.10e-3)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.22e-3)" "unprognostic (3.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (4.05e-1)" PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756253-60802086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm "Nuclear bodies, Cytosol" "CAB017795: , HPA035349: AB_2674583, HPA035350: AB_2674584" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 54.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.8;Enteroendocrine cells: 59.0;Extravillous trophoblasts: 98.0;Muller glia cells: 32.4;Oligodendrocytes: 35.1;Syncytiotrophoblasts: 76.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatogonia, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 8.1" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" Enzyme NA NA 2000000 "Cluster 58: Placenta - Pregnancy" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.5;retina: 61.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.1;Oligodendrocytes: 57.7;Rod photoreceptor cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 66: Photoreceptor cells - Visual perception" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 50.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 26.7;Distal enterocytes: 28.7;granulocytes: 38.2;Late spermatids: 123.7" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" 5 Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" PAQR7 "MPRA, mSR, PGLP" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 13 "Late spermatids: 1950.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Late spermatids - Spermatogenesis" 4 Cytosol "HPA046936: AB_2679869" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (8.03e-2)" "unprognostic (4.54e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.47e-1)" "unprognostic (4.59e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.05e-5)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.15e-2)" "unprognostic (1.54e-2)" PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.3" "Cell type enhanced" "Detected in many" "Astrocytes: 159.8;Distal enterocytes: 128.9;Microglial cells: 70.7;Oligodendrocytes: 277.5;Paneth cells: 81.2;Proximal enterocytes: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" PAQR9 "BLNC1, FLJ41938" ENSG00000188582 "Progestin and adipoQ receptor family member 9" Q6ZVX9 3 142949164-142963674 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 5.1;heart muscle: 6.4;liver: 13.1;retina: 9.3;testis: 19.8" "Cell type enhanced" "Detected in some" "Early spermatids: 44.1;Erythroid cells: 37.8;Hepatocytes: 24.5;Late spermatids: 97.4;Rod photoreceptor cells: 19.2;Syncytiotrophoblasts: 46.7" "Cancer enriched" "Detected in single" 15 "liver cancer: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.2" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052798 Uncertain NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Late spermatids - Spermatogenesis" "HPA052798: AB_2681955" "unprognostic (4.13e-2)" "unprognostic (2.54e-1)" "unprognostic (2.81e-1)" "unprognostic (3.09e-2)" "unprognostic (1.21e-2)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.56e-2)" "unprognostic (1.23e-2)" "unprognostic (1.09e-1)" "unprognostic (6.91e-2)" PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 271.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 15: Non-specific - Mixed function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 188.3;Distal enterocytes: 299.9;Intestinal goblet cells: 102.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 16 "B-cells: 8.1;dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "Myeloma: 39.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" 1 "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" PARP16 "ARTD15, C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Metabolic proteins, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 54.4;Rod photoreceptor cells: 32.0;Spermatogonia: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 27: T-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 189.1;tongue: 164.1" "Cell type enhanced" "Detected in many" "dendritic cells: 158.9;Erythroid cells: 107.2;granulocytes: 120.7;Hofbauer cells: 87.4" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003568, HPA072217" Enhanced Supported "Actin filaments,Cytosol" NA NA 24000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" 1 "Actin filaments, Cytosol" "HPA003568: , HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.1;lymphoid tissue: 29.3" "Cell type enhanced" "Detected in many" "B-cells: 62.2;dendritic cells: 78.6;Hofbauer cells: 89.0;Kupffer cells: 75.1;Langerhans cells: 61.5;Macrophages: 89.0;monocytes: 131.4;Schwann cells: 65.9;T-cells: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 55.5" "Adipose subcutaneous - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031833, HPA031834" Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 23 "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 81.6;retina: 66.8" "Group enriched" "Detected in some" 6 "Horizontal cells: 473.4;Muller glia cells: 408.8" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Region enhanced" "Detected in all" "cerebellum: 96.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 79 Nucleoplasm "CAB034143: AB_1127044, HPA030775: AB_10601243" "unprognostic (2.89e-1)" "unprognostic (2.98e-2)" "unprognostic (8.34e-2)" "unprognostic (3.85e-2)" "unprognostic (4.42e-2)" "unprognostic (7.82e-2)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.24e-3)" "unprognostic (1.68e-1)" "unprognostic (1.20e-2)" "unprognostic (3.91e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (3.42e-3)" PBXIP1 HPIP ENSG00000163346 "PBX homeobox interacting protein 1" Q96AQ6 1 154944076-154956123 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 691.6" "Cell type enhanced" "Detected in many" "Early spermatids: 139.0;Late spermatids: 180.6;Muller glia cells: 207.1;Peritubular cells: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 184.2;NK-cells: 57.0;T-cells: 197.9" "Cancer enhanced" "Detected in all" "Myeloma: 188.5" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006949, HPA073481" Approved Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 13 Nucleoplasm Cytosol "HPA006949: AB_1079572, HPA073481: " "unprognostic (6.17e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (8.94e-2)" "unprognostic (2.16e-1)" "prognostic favorable (7.19e-4)" "unprognostic (1.62e-1)" "prognostic favorable (8.99e-4)" "unprognostic (1.21e-1)" "unprognostic (2.46e-1)" "prognostic favorable (2.64e-4)" "unprognostic (1.20e-2)" "prognostic favorable (9.22e-6)" "unprognostic (3.89e-1)" "unprognostic (4.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.26e-3)" PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 58.8;Distal enterocytes: 46.8;Endothelial cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 76.0" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 36.2;placenta: 25.0;prostate: 10.3;seminal vesicle: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 55.1;Excitatory neurons: 62.6;Glandular and luminal cells: 32.1;Inhibitory neurons: 55.3;Oligodendrocyte precursor cells: 43.9;Oligodendrocytes: 55.5;Schwann cells: 26.4" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 88000 "Cluster 61: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 2 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: AB_1855041, HPA073462: AB_2686605" "unprognostic (7.20e-2)" "unprognostic (8.74e-3)" "unprognostic (4.30e-2)" "unprognostic (8.12e-5)" "unprognostic (8.33e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-3)" "unprognostic (4.51e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-3)" "unprognostic (8.72e-2)" "unprognostic (1.45e-1)" "unprognostic (8.68e-4)" "unprognostic (8.88e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-4)" PCDH11X "PCDH-X, PCDH11, PCDHX, PPP1R119" ENSG00000102290 "Protocadherin 11 X-linked" Q9BZA7 X 91779261-92623230 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.4;ovary: 5.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 115.7;Inhibitory neurons: 334.3;Oligodendrocyte precursor cells: 163.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.3" "Adipose visceral - Smooth muscle cells, Skin - Outer root sheath cells" HPA077495 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "HPA077495: " "unprognostic (4.22e-3)" "unprognostic (1.16e-1)" "unprognostic (1.39e-4)" "unprognostic (1.18e-1)" "unprognostic (8.20e-3)" "unprognostic (6.32e-2)" "unprognostic (9.10e-2)" "unprognostic (6.19e-2)" "unprognostic (4.58e-1)" "unprognostic (1.58e-1)" "unprognostic (2.45e-2)" "unprognostic (3.86e-1)" PCDH12 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.4;Endothelial cells: 25.7;Hofbauer cells: 32.4;Lymphatic endothelial cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 41 "monocytes: 4.7" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" "Cell adhesion" NA NA 14000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 18.4;retina: 59.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2782.3" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.3" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA074437 Supported "Intracellular and membrane" "Cell adhesion" NA NA 22000 "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;lung: 13.6;lymphoid tissue: 24.4" "Cell type enhanced" "Detected in many" "Astrocytes: 73.1;Early spermatids: 81.7;Endothelial cells: 110.7;Excitatory neurons: 120.7;Granulosa cells: 80.3;Inhibitory neurons: 65.0;Oligodendrocyte precursor cells: 181.1;Oligodendrocytes: 94.1;Spermatocytes: 59.0" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.2;Neuroblastoma: 6.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 34: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.1;Fibroblasts: 50.7;Leydig cells: 38.5;Ovarian stromal cells: 18.6;Peritubular cells: 56.2;Smooth muscle cells: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;testis cancer: 35.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" PCDH19 "EFMR, EIEE9, KIAA1313" ENSG00000165194 "Protocadherin 19" Q8TAB3 X 100291644-100410273 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Excitatory neurons: 23.7;Horizontal cells: 29.6;Inhibitory neurons: 49.5;Oligodendrocyte precursor cells: 38.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6;ovarian cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.8" "Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027533 Approved Approved Cytosol NA NA 83000 "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA027533: AB_10602043" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (5.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (4.77e-2)" "unprognostic (3.64e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-1)" "unprognostic (2.79e-1)" "unprognostic (9.77e-3)" "unprognostic (2.82e-3)" "unprognostic (1.53e-1)" "unprognostic (1.80e-4)" "unprognostic (1.37e-1)" PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415849 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;smooth muscle: 8.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 8.0;Inhibitory neurons: 7.6;Oligodendrocyte precursor cells: 30.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.8;Kidney cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 64: Neuronal - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-1)" "unprognostic (7.83e-2)" "unprognostic (6.79e-4)" "unprognostic (2.32e-2)" "unprognostic (1.56e-1)" "unprognostic (5.34e-4)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.12e-1)" PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720369-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 295.7;Excitatory neurons: 1113.8;Inhibitory neurons: 845.0;Oligodendrocyte precursor cells: 860.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" PCDH8 "ARCADLIN, PAPC" ENSG00000136099 "Protocadherin 8" O95206 13 52842889-52848641 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 13.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 16.0;Excitatory neurons: 24.0;Inhibitory neurons: 17.7;Muller glia cells: 21.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.6;Neuroblastoma: 2.4" "Colon - Colon enteroendocrine cells, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010509 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" "HPA010509: AB_10601384" "unprognostic (3.50e-3)" "unprognostic (6.48e-2)" "unprognostic (1.40e-1)" "unprognostic (9.11e-4)" "unprognostic (2.12e-2)" "unprognostic (1.97e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "unprognostic (3.59e-1)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 39.8" "Cell type enhanced" "Detected in many" "Astrocytes: 4115.7;Excitatory neurons: 5079.8;Inhibitory neurons: 2392.0;Oligodendrocyte precursor cells: 5924.5;Oligodendrocytes: 13140.4" "Cancer enriched" "Detected in single" 8 "glioma: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.6" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2900000 "Cluster 34: B-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" "Nucleoplasm, Centrosome" "HPA015581: AB_1855048" "unprognostic (1.77e-1)" "unprognostic (8.36e-2)" "unprognostic (9.12e-3)" "unprognostic (4.42e-5)" "unprognostic (7.54e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (8.47e-4)" "unprognostic (6.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.35e-4)" PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.8;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.0" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" "Endoplasmic reticulum, Golgi apparatus" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;parathyroid gland: 2.6;retina: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 8.9;Bipolar cells: 10.7;Horizontal cells: 8.2;Mesothelial cells: 5.0;Mucus glandular cells: 7.1;Secretory cells: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA035812: AB_2674796" "unprognostic (3.95e-2)" "unprognostic (7.74e-2)" "unprognostic (7.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-2)" "unprognostic (2.24e-2)" "unprognostic (2.08e-2)" "unprognostic (4.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-4)" "unprognostic (3.18e-4)" "unprognostic (1.11e-1)" "unprognostic (3.21e-3)" "unprognostic (6.97e-2)" PCDHA2 ENSG00000204969 "Protocadherin alpha 2" Q9Y5H9 5 140794852-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;pituitary gland: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA035653 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 13: Spermatids - Transcription" "HPA035653: AB_10670969" "unprognostic (3.54e-2)" "unprognostic (5.87e-2)" "unprognostic (3.27e-2)" "unprognostic (8.39e-3)" "unprognostic (4.61e-2)" "unprognostic (4.16e-3)" "unprognostic (1.23e-1)" "unprognostic (4.30e-2)" "unprognostic (3.35e-3)" "unprognostic (5.64e-6)" "unprognostic (2.17e-2)" "unprognostic (7.20e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-3)" "unprognostic (3.42e-1)" PCDHA4 "CNR1, CNRN1, CRNR1, PCDH-ALPHA4" ENSG00000204967 "Protocadherin alpha 4" Q9UN74 5 140806929-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.5;Early spermatids: 1.5;Horizontal cells: 1.3;Pancreatic endocrine cells: 1.7;Rod photoreceptor cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 5.9" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA043180, HPA073478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "Nucleoplasm, Plasma membrane" Cytosol "HPA043180: AB_10806381, HPA073478: AB_2686608" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (2.85e-1)" "unprognostic (5.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.14e-2)" "unprognostic (2.56e-1)" "unprognostic (7.90e-3)" "unprognostic (7.14e-3)" "unprognostic (7.00e-2)" "unprognostic (5.06e-3)" "unprognostic (6.94e-5)" "unprognostic (5.01e-3)" "unprognostic (6.21e-2)" "unprognostic (3.98e-1)" "unprognostic (6.29e-3)" "unprognostic (4.79e-2)" PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 2.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.6" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: AB_10970597" "unprognostic (4.95e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-1)" "unprognostic (8.81e-4)" "unprognostic (5.10e-2)" "unprognostic (6.25e-3)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (2.46e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-4)" "unprognostic (9.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.17e-5)" "unprognostic (2.11e-1)" PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" "Cell adhesion" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" PCDHA8 ENSG00000204962 "Protocadherin alpha 8" Q9Y5H6 5 140841187-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" HPA044585 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA044585: AB_10793953" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "unprognostic (4.20e-2)" "unprognostic (9.67e-2)" "unprognostic (8.58e-3)" "unprognostic (7.87e-4)" "unprognostic (5.62e-3)" "unprognostic (2.22e-2)" "unprognostic (5.48e-1)" "unprognostic (1.20e-2)" PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "parathyroid gland: 28.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 2.2;Alveolar cells type 2: 3.0;Bipolar cells: 1.5;Collecting duct cells: 1.9;Cone photoreceptor cells: 1.7;Rod photoreceptor cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2;Rhabdoid: 3.4" "Colon - Colon enteroendocrine cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: AB_2681942" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.32e-3)" "unprognostic (9.52e-3)" "unprognostic (1.36e-1)" "unprognostic (9.63e-2)" "unprognostic (4.27e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" "unprognostic (3.64e-3)" "unprognostic (1.04e-3)" "unprognostic (3.25e-3)" "unprognostic (1.35e-1)" "unprognostic (2.96e-1)" "unprognostic (3.29e-2)" PCDHAC2 PCDH-ALPHA-C2 ENSG00000243232 "Protocadherin alpha subfamily C, 2" Q9Y5I4 5 140966470-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 41.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.7;Alveolar cells type 2: 1.8;Collecting duct cells: 1.9;Cone photoreceptor cells: 1.7;Horizontal cells: 1.3;Mesothelial cells: 5.6;Rod photoreceptor cells: 1.2;Sertoli cells: 2.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076190 Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 61: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 50: Connective tissue cells - ECM organization" Nucleoplasm Mitochondria "HPA076190: AB_2686785" "unprognostic (1.47e-1)" "unprognostic (3.58e-3)" "unprognostic (2.59e-1)" "unprognostic (5.31e-4)" "unprognostic (3.89e-1)" "unprognostic (1.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (2.13e-2)" "unprognostic (2.45e-1)" "unprognostic (1.41e-1)" "unprognostic (2.30e-1)" "unprognostic (4.46e-4)" "unprognostic (9.90e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-3)" PCDHB1 PCDH-BETA1 ENSG00000171815 "Protocadherin beta 1" Q9Y5F3 5 141051374-141059346 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.5;Lymphatic endothelial cells: 2.7;Skeletal myocytes: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053921 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" Nucleoplasm "Plasma membrane" "HPA053921: AB_2682310" "unprognostic (5.54e-2)" "unprognostic (1.60e-2)" "unprognostic (9.01e-4)" "unprognostic (8.65e-2)" "unprognostic (8.00e-2)" "unprognostic (7.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (8.17e-5)" "unprognostic (3.38e-2)" "unprognostic (9.40e-2)" "unprognostic (1.23e-1)" "unprognostic (5.77e-4)" PCDHB10 ENSG00000120324 "Protocadherin beta 10" Q9UN67 5 141192353-141195647 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Bipolar cells: 6.4;Endometrial stromal cells: 3.2;Peritubular cells: 3.2;Sertoli cells: 5.4" "Cancer enhanced" "Detected in many" "glioma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6" "Heart muscle - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" "HPA013445: AB_1855054" "unprognostic (1.08e-1)" "unprognostic (8.41e-2)" "unprognostic (4.03e-2)" "unprognostic (1.51e-2)" "unprognostic (1.94e-1)" "unprognostic (7.30e-2)" "unprognostic (1.81e-2)" "unprognostic (2.74e-1)" "unprognostic (2.61e-2)" "unprognostic (3.96e-3)" "unprognostic (2.16e-1)" "unprognostic (3.25e-1)" "unprognostic (5.40e-3)" "unprognostic (4.56e-2)" "unprognostic (3.11e-2)" "unprognostic (1.76e-1)" "unprognostic (1.83e-3)" PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.2;Endometrial stromal cells: 3.2;Fibroblasts: 4.3;Peritubular cells: 2.8;Sertoli cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Bipolar cells: 4.3;Endometrial stromal cells: 2.5;Fibroblasts: 2.6;Peritubular cells: 2.0;Skeletal myocytes: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Early spermatids" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.1;Early spermatids: 12.0;Peritubular cells: 7.6;Skeletal myocytes: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.8" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 66: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 13 Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" PCDHB15 PCDH-BETA15 ENSG00000113248 "Protocadherin beta 15" Q9Y5E8 5 141245395-141249365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 4.0;Bipolar cells: 4.3;Early spermatids: 8.0;Endometrial stromal cells: 3.9;Fibroblasts: 4.3;Horizontal cells: 3.8;Ovarian stromal cells: 3.5;Smooth muscle cells: 3.5;Spermatocytes: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 4.5" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA007172, CAB026471, HPA074676" Uncertain Approved Mitochondria NA NA 250000 "Cluster 64: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" Mitochondria "CAB026471: , HPA007172: AB_1079576, HPA074676: AB_2732263" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (7.37e-3)" "unprognostic (1.75e-1)" "unprognostic (2.06e-2)" "unprognostic (6.19e-2)" "unprognostic (1.60e-1)" "unprognostic (4.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.58e-2)" "unprognostic (7.01e-2)" "unprognostic (6.00e-2)" "unprognostic (9.37e-2)" "unprognostic (1.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 8.1;Cholangiocytes: 7.6;Endometrial stromal cells: 8.2;Fibroblasts: 6.6;Ovarian stromal cells: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" PCDHB2 PCDH-BETA2 ENSG00000112852 "Protocadherin beta 2" Q9Y5E7 5 141094606-141098703 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 6.8;Melanocytes: 5.2;Spermatocytes: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in many" HPA007548 Enhanced Approved Nucleoplasm NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" Nucleoplasm "HPA007548: AB_2667859" "unprognostic (2.94e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-4)" "unprognostic (1.31e-1)" "unprognostic (3.03e-3)" "unprognostic (7.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.24e-1)" "unprognostic (3.99e-1)" "unprognostic (2.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (4.84e-4)" PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Endometrial stromal cells: 2.5;Fibroblasts: 1.8;Horizontal cells: 3.1;Sertoli cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 9: Endometrial stromal cells - Transcription" 1 Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 8.7;Endometrial stromal cells: 8.2;Fibroblasts: 10.6;Horizontal cells: 6.3;Peritubular cells: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear membrane" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" PCDHB5 "DKFZp586B0217, PCDH-BETA5" ENSG00000113209 "Protocadherin beta 5" Q9Y5E4 5 141135206-141138615 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 10.4;Ovarian stromal cells: 6.0;Prostatic glandular cells: 5.4;Spermatocytes: 10.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 20.0" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA013191, HPA067473" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Spermatocytes - Spermatogenesis" 2 "Plasma membrane" Vesicles "HPA013191: AB_1855059, HPA067473: " "unprognostic (2.21e-1)" "unprognostic (4.71e-2)" "unprognostic (4.05e-3)" "unprognostic (1.81e-1)" "unprognostic (2.84e-2)" "unprognostic (5.23e-2)" "unprognostic (2.27e-2)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.06e-3)" "unprognostic (6.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-3)" PCDHB6 PCDH-BETA6 ENSG00000113211 "Protocadherin beta 6" Q9Y5E3 5 141150057-141153287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Lymphatic endothelial cells: 3.5;Sertoli cells: 2.7;Spermatocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.5" "Testis - Early spermatids" "Low region specificity" "Detected in many" "HPA029566, HPA075308" Uncertain Approved Nucleoplasm NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA029566: AB_10601385, HPA075308: " "unprognostic (3.25e-2)" "unprognostic (1.54e-2)" "unprognostic (1.81e-1)" "unprognostic (8.05e-2)" "unprognostic (7.65e-3)" "unprognostic (2.82e-1)" "unprognostic (1.73e-3)" "unprognostic (9.64e-3)" "unprognostic (8.62e-2)" "unprognostic (1.54e-3)" "unprognostic (2.28e-2)" "unprognostic (6.33e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.60e-4)" "unprognostic (2.31e-2)" "unprognostic (7.08e-3)" "unprognostic (6.52e-2)" PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Early spermatids: 43.5;Late spermatids: 29.1;Spermatocytes: 20.6" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" PCDHB8 "PCDH-BETA8, PCDH3I" ENSG00000120322 "Protocadherin beta 8" Q9UN66 5 141177790-141180539 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Early spermatids: 6.7;Spermatocytes: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" HPA057773 Uncertain NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA057773: AB_2683525" "unprognostic (1.16e-3)" "unprognostic (1.56e-1)" "unprognostic (5.33e-2)" "unprognostic (1.72e-1)" "unprognostic (7.56e-2)" "unprognostic (2.02e-2)" "unprognostic (5.72e-3)" "unprognostic (5.82e-4)" "unprognostic (3.54e-2)" "unprognostic (5.52e-3)" "unprognostic (1.95e-2)" "unprognostic (2.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.11e-2)" "unprognostic (8.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.30e-4)" PCDHB9 "PCDH-BETA9, PCDH3H" ENSG00000177839 "Protocadherin beta 9" Q9Y5E1 5 141187127-141191541 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 17.0;Horizontal cells: 12.6;Ovarian stromal cells: 4.3" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.4" "Lung - Fibroblast_1, Prostate - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA013445: AB_1855054" "unprognostic (1.85e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-1)" "unprognostic (8.97e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.12e-1)" "unprognostic (6.78e-3)" "unprognostic (1.34e-2)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (1.86e-4)" "unprognostic (1.71e-1)" "unprognostic (9.80e-2)" "unprognostic (1.17e-1)" "unprognostic (8.01e-2)" PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330514-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.3;Horizontal cells: 1.3;Melanocytes: 1.7;Skeletal myocytes: 6.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.9;Horizontal cells: 15.1;Skeletal myocytes: 66.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Bipolar cells: 3.0;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.9;Fibroblasts: 3.5;Lymphatic endothelial cells: 7.4;Mesothelial cells: 3.9;Skeletal myocytes: 10.7" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 5.8;skin cancer: 5.7" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 34: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.0;Fibroblasts: 2.3;Peritubular cells: 1.6;Schwann cells: 4.3;Skeletal myocytes: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.1;Fibroblasts: 2.2;Horizontal cells: 1.9;Ovarian stromal cells: 1.9;Schwann cells: 5.4;Skeletal myocytes: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364162-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.6;Endometrial stromal cells: 8.7;Skeletal myocytes: 31.2" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.5;Skeletal myocytes: 26.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Endometrial stromal cells: 2.1;Prostatic glandular cells: 2.4;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.8;Horizontal cells: 5.0;Ovarian stromal cells: 5.2;Skeletal myocytes: 21.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402778-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.7;Cardiomyocytes: 2.3;Horizontal cells: 2.5;Skeletal myocytes: 7.8" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350099-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.4" "Group enriched" "Detected in some" 6 "Early spermatids: 3.7;Late spermatids: 8.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 61: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141359994-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Cardiomyocytes: 2.0;Mucus glandular cells: 1.1" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Salivary duct cells: 1.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblast_1" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Lymphatic endothelial cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.7;testis cancer: 14.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397947-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.6;Mucus glandular cells: 1.8;Skeletal myocytes: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 8.2;Skeletal myocytes: 16.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 55: Non-specific - Transcription" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Fibroblasts: 4.3;Lymphatic endothelial cells: 8.6;Schwann cells: 5.6;Skeletal myocytes: 8.8" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2;Rhabdoid: 16.1" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 351.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 6.2;Bipolar cells: 7.5;Fibroblasts: 12.6;Mesothelial cells: 10.8;Serous glandular cells: 9.0;Skeletal myocytes: 7.8" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 25 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 49: Non-specific - Transcription" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512975 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 19.4;retina: 6.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 3.1;testis cancer: 9.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 29.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;testis cancer: 6.8" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.4;pituitary gland: 10.8;retina: 21.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 632.9;Horizontal cells: 173.1;Inhibitory neurons: 715.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nuclear speckles" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749444-149811420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 704.0;Late spermatids: 730.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 4100000 "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" 3 Cytosol "HPA003239: AB_1079580" "prognostic unfavorable (4.02e-7)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.88e-4)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavorable (6.38e-4)" PCNX1 "KIAA0805, KIAA0995, PCNX, PCNXL1, pecanex" ENSG00000100731 "Pecanex 1" Q96RV3 14 70907405-71115382 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 158.0;Inhibitory neurons: 149.5;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048970, HPA053532" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm "HPA048970: , HPA053532: AB_2682180" "unprognostic (1.96e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "unprognostic (2.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (7.41e-2)" "unprognostic (1.04e-2)" "unprognostic (4.16e-2)" "unprognostic (5.56e-2)" "prognostic favorable (4.05e-5)" "unprognostic (9.01e-3)" "unprognostic (2.90e-1)" "unprognostic (8.11e-2)" "unprognostic (7.37e-2)" PCNX2 "FLJ11383, KIAA0435, PCNXL2" ENSG00000135749 "Pecanex 2" A6NKB5 1 232983435-233295725 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 253.5;Inhibitory neurons: 225.9;Microglial cells: 131.5;Oligodendrocyte precursor cells: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013815, HPA014427" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA013815: AB_2236561, HPA014427: AB_1855081" "unprognostic (3.15e-1)" "unprognostic (5.61e-3)" "unprognostic (1.92e-2)" "unprognostic (1.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.71e-1)" "unprognostic (4.25e-2)" "unprognostic (3.79e-1)" "unprognostic (2.40e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.27e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" PCNX3 "FLJ22427, PCNXL3" ENSG00000197136 "Pecanex 3" Q9H6A9 11 65615776-65637439 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018084 Uncertain Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Non-specific - DNA binding" Cytosol "HPA018084: AB_1855083" "unprognostic (9.93e-2)" "unprognostic (1.33e-1)" "unprognostic (5.46e-2)" "unprognostic (1.09e-2)" "unprognostic (2.54e-1)" "unprognostic (1.70e-2)" "unprognostic (3.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (7.69e-3)" "unprognostic (7.06e-2)" "unprognostic (2.44e-2)" "unprognostic (8.52e-3)" "unprognostic (6.51e-3)" "unprognostic (1.93e-1)" "unprognostic (2.32e-2)" "unprognostic (4.82e-1)" PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Non-specific - Transcription" 1 Cytosol "HPA002076: AB_1078322, HPA003390: AB_2066703" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.83e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "prognostic favorable (6.84e-5)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (8.59e-2)" PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 64.1" "Group enriched" "Detected in many" 5 "Early spermatids: 239.1;Late spermatids: 664.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005572 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favorable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 179.9;Inhibitory neurons: 78.0;Oligodendrocyte precursor cells: 140.1;Proximal enterocytes: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 10 "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.5;lymphoid tissue: 15.7" "Cell type enriched" "Detected in some" 4 "T-cells: 34.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 3.1" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;lymphoma: 1.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.7;Fibroblasts: 7.3;granulocytes: 11.8;Langerhans cells: 13.9;Leydig cells: 6.8;Microglial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" Receptor NA NA 31000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Langerhans cells - Innate immune response" 18 Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 41.9" "Cell type enhanced" "Detected in many" "Astrocytes: 93.2;Bipolar cells: 79.2;Cardiomyocytes: 209.8;Horizontal cells: 95.7;Inhibitory neurons: 75.1;Smooth muscle cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.4" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 62.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.9;Excitatory neurons: 135.7;Inhibitory neurons: 151.5;Microglial cells: 183.4;Oligodendrocyte precursor cells: 111.3;T-cells: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.9;T-cells: 6.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Liver - Plasma proteins" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 193.9" "Group enriched" "Detected in many" 9 "Endometrial stromal cells: 368.4;Fibroblasts: 258.5;Leydig cells: 422.2;Oligodendrocyte precursor cells: 468.8;Ovarian stromal cells: 204.8;Peritubular cells: 377.5" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 78.7;thyroid cancer: 38.5" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Receptor NA NA 300000 "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 138.3;Leydig cells: 158.6;Peritubular cells: 202.3;Sertoli cells: 514.0;Smooth muscle cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 36.3;testis cancer: 35.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 33: Non-specific - ATP binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 21 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1335.8;Plasma cells: 981.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Enzyme NA NA 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125555 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Enteroendocrine cells - Hormone signaling" 5 Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 607.3;skeletal muscle: 1122.4;tongue: 553.7" "Group enriched" "Detected in all" 5 "Cardiomyocytes: 2644.4;Skeletal myocytes: 856.8" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 217.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 217.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 32: Basophils - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 9 "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" PDPN "aggrus, D2-40, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins, Transporters" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 130.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 92.0;Basal respiratory cells: 92.5;Lymphatic endothelial cells: 304.9;Mesothelial cells: 319.3;Muller glia cells: 79.4" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 109.6;thyroid cancer: 97.5" "Breast - Fibroblasts, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 1 "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1015.7" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 4797.2" "Cancer enhanced" "Detected in all" "renal cancer: 340.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 497.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 71 Cytosol "Nuclear speckles" "HPA014907: AB_1855166" "unprognostic (2.97e-1)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (8.14e-3)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (2.64e-2)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-3)" "unprognostic (1.89e-1)" PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916429 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.5;Endothelial cells: 28.1;Granulosa cells: 16.8;Leydig cells: 42.9;Lymphatic endothelial cells: 46.1;Peritubular cells: 32.3;Sertoli cells: 19.0;Smooth muscle cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centriolar satellite" NA NA 62000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Smooth muscle cells - Signal transduction" 2 "Nucleoplasm, Cell Junctions, Centriolar satellite" "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 439.6" "Cell type enhanced" "Detected in many" "Adipocytes: 681.6;Endothelial cells: 592.8;Lymphatic endothelial cells: 217.7;monocytes: 309.0;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 706.3" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Leukemia: 41.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 58: Placenta - Pregnancy" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 58 "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.0;Late spermatids: 123.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "Endoplasmic reticulum" "HPA059549: AB_2684059" "unprognostic (3.11e-2)" "unprognostic (7.04e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-3)" "unprognostic (7.00e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (8.63e-2)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.79e-11)" "unprognostic (1.85e-1)" "unprognostic (1.20e-1)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" PEDS1-UBE2V1 "CROC-1B, Kua-UEV, TMEM189-UBE2V1" ENSG00000124208 "PEDS1-UBE2V1 readthrough" 20 50081124-50153637 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.3;Inhibitory neurons: 2.1;Late spermatids: 4.6;Microglial cells: 1.8;Oligodendrocytes: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA052535, HPA053186" Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "HPA052535: AB_2681863, HPA053186: AB_2682073" "unprognostic (3.69e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-3)" "unprognostic (2.71e-2)" "unprognostic (1.52e-1)" "unprognostic (6.05e-3)" "unprognostic (2.40e-1)" "unprognostic (8.19e-2)" PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 162.2;liver: 260.8" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 127.3;Hepatocytes: 213.1;Pancreatic endocrine cells: 171.5;Peritubular cells: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 760.9;skin 1: 1079.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3367.5;Squamous epithelial cells: 3783.0;Suprabasal keratinocytes: 7466.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 40.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 40.0" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 7 "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" PEX10 RNF69 ENSG00000157911 "Peroxisomal biogenesis factor 10" O60683 1 2403964-2413797 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport, Ubl conjugation pathway" Transferase "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049755 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" "HPA049755: AB_2680867" "prognostic favorable (4.50e-6)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (8.15e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (1.81e-2)" "unprognostic (2.91e-1)" "unprognostic (9.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.16e-6)" "unprognostic (4.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" PEX11B PEX11beta ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 1 Vesicles Nucleoplasm "HPA017150: , HPA050104: AB_2681017" "unprognostic (4.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.62e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.67e-4)" "prognostic favorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (2.10e-1)" "unprognostic (8.48e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.62e-3)" "unprognostic (4.28e-1)" PEX11G PEX11gamma ENSG00000104883 "Peroxisomal biogenesis factor 11 gamma" Q96HA9 19 7476875-7497449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 25.8;testis: 28.2" "Cell type enhanced" "Detected in many" "Early spermatids: 93.7;Hepatocytes: 43.7;Late spermatids: 72.5;Proximal enterocytes: 36.9;Proximal tubular cells: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA069817 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 5 "HPA069817: AB_2686207" "unprognostic (2.26e-2)" "unprognostic (6.44e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.60e-4)" "unprognostic (1.01e-1)" "unprognostic (4.09e-3)" "prognostic favorable (3.27e-4)" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" "unprognostic (2.32e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.83e-9)" "unprognostic (1.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.19e-2)" PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 20.8;Spermatocytes: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" 31 "HPA069386: AB_2686135" "unprognostic (1.45e-1)" "unprognostic (6.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (9.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (5.55e-2)" "unprognostic (2.64e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" PEX13 ENSG00000162928 "Peroxisomal biogenesis factor 13" Q92968 2 61017225-61051990 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 157.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA032141, HPA032142, CAB032689" Enhanced Supported Peroxisomes NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 Peroxisomes "CAB032689: AB_2162137, HPA032141: AB_2674176, HPA032142: AB_10669676" "unprognostic (2.44e-3)" "unprognostic (4.10e-2)" "unprognostic (7.84e-3)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (5.08e-2)" "unprognostic (2.05e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (5.42e-2)" "unprognostic (4.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (2.63e-2)" PEX14 ENSG00000142655 "Peroxisomal biogenesis factor 14" O75381 1 10472288-10630758 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 62.6;Syncytiotrophoblasts: 63.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046104, HPA049231" Supported Supported "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 66: Photoreceptor cells - Visual perception" 7 Peroxisomes "Nucleoli fibrillar center" "HPA046104: AB_2679539, HPA049231: AB_2680683" "unprognostic (7.23e-3)" "unprognostic (7.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-2)" "unprognostic (3.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.32e-2)" "unprognostic (2.32e-1)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (3.05e-3)" "unprognostic (9.67e-3)" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (3.75e-2)" PEX16 ENSG00000121680 "Peroxisomal biogenesis factor 16" Q9Y5Y5 11 45909663-45918812 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043286 Approved NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 23 "HPA043286: AB_10794179" "unprognostic (2.48e-1)" "unprognostic (1.95e-2)" "unprognostic (8.14e-2)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (9.06e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-3)" "unprognostic (1.51e-1)" "unprognostic (6.75e-3)" "unprognostic (5.72e-3)" "unprognostic (2.71e-1)" "unprognostic (1.00e-1)" "prognostic favorable (9.06e-4)" PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport, Ubl conjugation pathway" Transferase "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 172.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" PEX26 FLJ20695 ENSG00000215193 "Peroxisomal biogenesis factor 26" Q7Z412 22 18077923-18105396 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 107.9;Proximal enterocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070429 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Small intestine - Absorption" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Enterocytes - Absorption" 28 "CAB070429: AB_11154363" "unprognostic (2.25e-1)" "unprognostic (5.75e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.77e-3)" "unprognostic (5.46e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (1.59e-2)" "unprognostic (5.34e-2)" "unprognostic (8.19e-2)" "unprognostic (1.88e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.38e-4)" "unprognostic (3.17e-3)" "unprognostic (4.53e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" PEX3 ENSG00000034693 "Peroxisomal biogenesis factor 3" P56589 6 143450805-143490616 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 72.2;Syncytiotrophoblasts: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042830, HPA058006" Supported Approved Nucleoplasm,Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Nucleoplasm, Peroxisomes" "HPA042830: AB_10794918, HPA058006: AB_2683576" "unprognostic (3.52e-3)" "unprognostic (6.28e-2)" "unprognostic (1.81e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (4.16e-1)" "unprognostic (8.45e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "prognostic favorable (3.80e-4)" "unprognostic (1.87e-1)" "unprognostic (7.30e-2)" "unprognostic (3.80e-2)" "unprognostic (2.12e-1)" PFDN1 PFD1 ENSG00000113068 "Prefoldin subunit 1" O60925 5 140245035-140303113 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006499 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 4 "Plasma membrane, Cytosol" Nucleoli "HPA006499: AB_1079596" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.11e-2)" "unprognostic (5.66e-3)" "prognostic unfavorable (8.81e-5)" "unprognostic (2.12e-2)" "unprognostic (2.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (4.10e-1)" "unprognostic (8.60e-3)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.00e-1)" PFN2 ENSG00000070087 "Profilin 2" P35080 3 149964904-150050788 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 448.7;Muller glia cells: 268.6;Oocytes: 381.6;Proximal tubular cells: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035611, CAB037073" Enhanced NA NA 19000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 10: Muller glia cells - Visual perception" 3 "CAB037073: AB_1079600, HPA035611: AB_10672870" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.42e-4)" "prognostic unfavorable (2.19e-7)" "unprognostic (4.11e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-2)" "unprognostic (2.96e-3)" "unprognostic (4.86e-3)" "unprognostic (6.82e-2)" "unprognostic (1.25e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.99e-1)" PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 211.1" "Cell type enhanced" "Detected in many" "Early spermatids: 122.1;Late spermatids: 306.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Fibroblast_1, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 2 Microtubules "HPA063099: AB_2684940" "unprognostic (1.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (3.18e-2)" "unprognostic (5.13e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (3.85e-2)" "unprognostic (4.66e-3)" "unprognostic (4.13e-2)" "unprognostic (2.17e-2)" "unprognostic (2.67e-2)" PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 77.4;Esophageal cancer: 77.4" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041, HPA057220" Uncertain Uncertain "Endoplasmic reticulum,Vesicles" NA Yes "Cluster 80: Non-specific - Endocytosis" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" Vesicles "HPA011318: AB_2668482, HPA054041: AB_2682353, HPA057220: " "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-GPI attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 77.7;Syncytiotrophoblasts: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 4: Neutrophils - Degranulation" "Cluster 46: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 9 Nucleoplasm "Cytokinetic bridge" "HPA051281: AB_2681418, HPA064673: AB_2685317" "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 250.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 132.3" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 4 "Bone cancer: 4.9;breast cancer: 5.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" Immunity NA NA 87000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Plasma proteins" "Cluster 27: Breast cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 656.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 473.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Approved "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 9: Endometrial stromal cells - Transcription" 15 "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" PGRMC2 "DG6, PMBP" ENSG00000164040 "Progesterone receptor membrane component 2" O15173 4 128269237-128288829 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 312.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041172, HPA058652" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 76000 "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Plasma cells - Protein processing" 53 "Nuclear bodies, Plasma membrane, Cytosol" "HPA041172: AB_2677345, HPA058652: AB_2683786" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "prognostic favorable (3.62e-4)" "unprognostic (6.03e-2)" "unprognostic (6.57e-3)" "unprognostic (2.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (8.24e-2)" "unprognostic (9.04e-2)" "unprognostic (3.80e-2)" "prognostic favorable (9.60e-4)" "unprognostic (3.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (6.03e-2)" PHACTR1 "dJ257A7.2, KIAA1733, RPEL1" ENSG00000112137 "Phosphatase and actin regulator 1" Q9C0D0 6 12716312-13290446 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Protein phosphatase inhibitor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.5;brain: 40.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1890.1;Inhibitory neurons: 501.5" "Cancer enriched" "Detected in many" 5 "melanoma: 10.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.1;plasmacytoid DC: 18.7" "Group enriched" "Detected in many" 13 "B-cells: 6.9;dendritic cells: 18.7;granulocytes: 16.1" "Cancer enhanced" "Detected in many" "lymphoma: 34.9;Myeloma: 29.5;skin cancer: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029755, HPA029756, HPA029757" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane" "HPA029755: AB_10600089, HPA029756: AB_10601852, HPA029757: AB_10669870" "unprognostic (7.86e-2)" "unprognostic (7.49e-2)" "unprognostic (2.74e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (7.72e-2)" "unprognostic (4.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-4)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (5.00e-2)" "unprognostic (1.16e-1)" PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "skeletal muscle: 280.7;tongue: 170.7" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 108.3" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Fibroblasts - ECM organization" "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748293-30761176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 126.5" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1535.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 3 Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 116.3;Basal keratinocytes: 164.5;Cardiomyocytes: 148.5;Mucus glandular cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" 2 "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" PHTF1 PHTF ENSG00000116793 "Putative homeodomain transcription factor 1" Q9UMS5 1 113696831-113759489 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 226.1;Excitatory neurons: 90.2;Inhibitory neurons: 98.4;Late spermatids: 125.7;Spermatocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059486 Approved "Nucleoli,Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoli "HPA059486: " "unprognostic (1.52e-1)" "unprognostic (3.33e-1)" "unprognostic (2.58e-2)" "unprognostic (4.54e-2)" "unprognostic (5.92e-2)" "unprognostic (1.62e-2)" "unprognostic (6.55e-2)" "unprognostic (1.30e-1)" "unprognostic (3.30e-3)" "unprognostic (1.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" PHTF2 DKFZp434D166 ENSG00000006576 "Putative homeodomain transcription factor 2" Q8N3S3 7 77798773-77957503 "Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 107.2;tongue: 52.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.4;Inhibitory neurons: 90.7;monocytes: 112.7;Oligodendrocytes: 134.4" "Cancer enhanced" "Detected in all" "testis cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 25.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012312 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm Cytosol "HPA012312: AB_2668649" "unprognostic (1.96e-1)" "unprognostic (2.60e-3)" "unprognostic (4.04e-1)" "unprognostic (1.44e-1)" "unprognostic (5.70e-2)" "unprognostic (1.99e-3)" "unprognostic (5.36e-3)" "unprognostic (2.81e-2)" "unprognostic (1.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.86e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.09e-7)" "unprognostic (8.28e-3)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (5.53e-2)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 135.5;heart muscle: 123.5;vagina: 123.4" "Group enriched" "Detected in many" 6 "Fibroblasts: 179.7;Leydig cells: 199.8;Oligodendrocytes: 62.7;Peritubular cells: 141.8" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.3" "Lineage enriched" "Detected in many" 5 "T-cells: 66.3" "Cancer enriched" "Detected in some" 12 "Kidney cancer: 17.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 45.1" HPA076574 Approved "Secreted to blood" "Enzyme inhibitor" NA NA 2900000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.1;Inhibitory neurons: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" PIANP "C12orf53, DKFZp547D2210, PANP" ENSG00000139200 "PILR alpha associated neural protein" Q8IYJ0 12 6693791-6700815 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 142.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.0;Excitatory neurons: 23.6;Horizontal cells: 27.1;Inhibitory neurons: 22.9;Oligodendrocyte precursor cells: 15.1;Peritubular cells: 13.9" "Group enriched" "Detected in many" 4 "glioma: 14.7;testis cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 30.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010631 Enhanced Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 Nucleoplasm "HPA010631: AB_10603680" "unprognostic (1.82e-1)" "unprognostic (9.21e-3)" "unprognostic (1.62e-2)" "unprognostic (7.65e-2)" "unprognostic (1.34e-1)" "unprognostic (3.03e-2)" "unprognostic (6.58e-2)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (6.41e-3)" "unprognostic (1.92e-2)" "unprognostic (3.89e-1)" "unprognostic (3.30e-3)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 65.3" "Cell type enhanced" "Detected in all" "Early spermatids: 486.3;Late spermatids: 556.7;Spermatocytes: 207.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068792, HPA077584" Enhanced Enhanced Nucleoplasm Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Testis - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 13: Non-specific - Mixed function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 16 Nucleoplasm "HPA068792: AB_2686037, HPA077584: " "unprognostic (9.59e-3)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.25e-1)" "unprognostic (6.39e-2)" "unprognostic (1.05e-3)" "unprognostic (3.67e-2)" "unprognostic (1.05e-1)" "unprognostic (3.71e-3)" "unprognostic (1.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (6.92e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.71e-1)" PIEZO1 "FAM38A, KIAA0233" ENSG00000103335 "Piezo type mechanosensitive ion channel component 1" Q92508 16 88715338-88785220 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA047185 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "HPA047185: AB_2679973" "unprognostic (1.76e-1)" "prognostic unfavorable (2.37e-4)" "unprognostic (1.77e-1)" "unprognostic (1.12e-2)" "unprognostic (4.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (4.39e-2)" "prognostic unfavorable (3.78e-4)" "unprognostic (3.51e-2)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (2.04e-1)" "unprognostic (3.59e-2)" "unprognostic (2.86e-2)" "unprognostic (3.74e-1)" PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 371.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 22.3;liver cancer: 17.2" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" PIGA "GPI3, PIG-A" ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 62.9;Langerhans cells: 52.3;monocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" 5 "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 73: B-cells - B-cell function" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" PIGC ENSG00000135845 "Phosphatidylinositol glycan anchor biosynthesis class C" Q92535 1 172370189-172444086 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036663 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 2 "HPA036663: AB_10669912" "unprognostic (3.35e-1)" "unprognostic (3.01e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (2.65e-1)" "unprognostic (3.72e-3)" "prognostic unfavorable (4.49e-4)" "unprognostic (7.25e-2)" "unprognostic (2.20e-2)" "unprognostic (4.69e-2)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.43e-8)" "unprognostic (1.09e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" "unprognostic (1.90e-1)" PIGF ENSG00000151665 "Phosphatidylinositol glycan anchor biosynthesis class F" Q07326 2 46580937-46617055 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051389 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 8 "HPA051389: AB_2681464" "unprognostic (3.85e-3)" "unprognostic (5.42e-2)" "unprognostic (1.11e-3)" "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (4.52e-3)" "prognostic unfavorable (1.39e-5)" "unprognostic (4.97e-2)" "unprognostic (9.29e-3)" "unprognostic (6.08e-2)" "unprognostic (5.89e-2)" "unprognostic (9.40e-2)" "unprognostic (1.02e-1)" "unprognostic (7.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.04e-2)" "unprognostic (6.71e-2)" PIGG "FLJ20265, GPI7, LAS21" ENSG00000174227 "Phosphatidylinositol glycan anchor biosynthesis class G" Q5H8A4 4 499210-540200 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015997 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 80: Non-specific - Transcription" "HPA015997: AB_2164679" "unprognostic (3.87e-2)" "unprognostic (5.32e-2)" "unprognostic (5.78e-3)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.20e-3)" "unprognostic (3.48e-2)" "unprognostic (4.68e-1)" "unprognostic (2.64e-1)" "unprognostic (7.01e-3)" "unprognostic (6.61e-3)" "unprognostic (9.09e-2)" "unprognostic (1.83e-2)" "unprognostic (1.51e-1)" "unprognostic (4.27e-3)" "unprognostic (2.97e-2)" PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600286 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autism spectrum disorder, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 10: Muller glia cells - Visual perception" 1 "HPA031624: AB_10601046" "unprognostic (1.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (3.47e-2)" "unprognostic (8.25e-3)" "unprognostic (8.69e-3)" "unprognostic (3.26e-3)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (6.17e-3)" "unprognostic (1.39e-1)" "prognostic favorable (2.68e-7)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (7.00e-2)" "unprognostic (3.73e-1)" PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088989-77219430 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 2 "HPA056383: AB_2683109, HPA057040: AB_2683319" "unprognostic (2.43e-2)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (2.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.07e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" PIGM GPI-MT-I ENSG00000143315 "Phosphatidylinositol glycan anchor biosynthesis class M" Q9H3S5 1 160024953-160031990 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA047418 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 10: Muller glia cells - Visual perception" "HPA047418: AB_2680039" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (1.37e-1)" "unprognostic (1.58e-1)" "unprognostic (9.89e-2)" "unprognostic (2.88e-2)" "unprognostic (2.69e-3)" "unprognostic (1.52e-1)" "unprognostic (3.85e-2)" "prognostic favorable (3.27e-4)" "unprognostic (2.63e-2)" "unprognostic (2.77e-2)" "unprognostic (3.01e-2)" "unprognostic (8.55e-2)" "unprognostic (1.69e-1)" "unprognostic (2.06e-2)" "unprognostic (1.50e-1)" PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Parietal cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Non-specific - Receptor signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" PIGO "DKFZp434M222, FLJ00135" ENSG00000165282 "Phosphatidylinositol glycan anchor biosynthesis class O" Q8TEQ8 9 35087237-35096619 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014905 Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA014905: AB_1855369" "unprognostic (1.41e-2)" "unprognostic (1.06e-1)" "unprognostic (4.03e-1)" "unprognostic (3.54e-1)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (6.98e-3)" "unprognostic (4.14e-2)" "unprognostic (5.08e-2)" "unprognostic (2.25e-1)" "unprognostic (3.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (3.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (5.23e-3)" "unprognostic (3.81e-2)" PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 370.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 53: Non-specific - Glycosylation" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 19 Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Testis - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 3 "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2560.5;salivary gland: 1591.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 9136.7;Enteroendocrine cells: 1484.9;Intestinal goblet cells: 1895.6;Paneth cells: 2797.4;Proximal enterocytes: 1597.7;Serous glandular cells: 1581.6;Undifferentiated cells: 3247.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 29.7;colorectal cancer: 30.9;Gastric cancer: 55.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" "No annotated function" NA NA 1300000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" PIGS ENSG00000087111 "Phosphatidylinositol glycan anchor biosynthesis class S" Q96S52 17 28553383-28571794 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018149 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 11 "HPA018149: AB_1855373" "unprognostic (2.29e-2)" "unprognostic (1.37e-2)" "unprognostic (3.89e-1)" "unprognostic (2.52e-1)" "unprognostic (6.61e-2)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.65e-1)" "unprognostic (9.09e-2)" "unprognostic (2.25e-3)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (2.90e-2)" "unprognostic (1.23e-1)" "unprognostic (8.06e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (5.31e-4)" PIGU "bA346K17.2, CDC91L1, GAB1" ENSG00000101464 "Phosphatidylinositol glycan anchor biosynthesis class U" Q9H490 20 34560542-34698790 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041706, HPA046766" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" 2 Nucleoplasm Cytosol "HPA041706: AB_2677627, HPA046766: AB_2679794" "unprognostic (1.87e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.64e-1)" "unprognostic (8.42e-3)" "unprognostic (7.94e-3)" "unprognostic (2.69e-1)" "unprognostic (9.86e-2)" "unprognostic (8.82e-3)" "unprognostic (3.75e-1)" "unprognostic (1.55e-1)" "unprognostic (5.27e-2)" "unprognostic (4.21e-3)" PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.5;Late spermatids: 96.2;Spermatocytes: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Testis - Spermatid development" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Spermatocytes - Spermatogenesis" 3 Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (8.40e-2)" "unprognostic (4.44e-2)" "prognostic favorable (7.60e-7)" "unprognostic (1.71e-1)" "unprognostic (4.24e-1)" "unprognostic (8.92e-2)" "unprognostic (5.96e-3)" PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA023499: " "unprognostic (4.96e-3)" "unprognostic (3.84e-2)" "unprognostic (5.40e-3)" "unprognostic (7.39e-2)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (8.14e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (4.62e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 33: Non-specific - DNA binding" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: AB_10610280, HPA073301: " "unprognostic (8.83e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.14e-1)" "unprognostic (2.42e-3)" "unprognostic (9.25e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.01e-1)" PIGY MGC14156 ENSG00000255072 "Phosphatidylinositol glycan anchor biosynthesis class Y" Q3MUY2 4 88520998-88523776 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059018 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" 3 "HPA059018: AB_2683884" PIGZ "FLJ12768, MGC52163, SMP3" ENSG00000119227 "Phosphatidylinositol glycan anchor biosynthesis class Z" Q86VD9 3 196946356-196969060 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;intestine: 38.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.9;Intestinal goblet cells: 61.8;Paneth cells: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA058599, HPA059920" Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 80: Non-specific - Endocytosis" "Cluster 1: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA058599: AB_2683771, HPA059920: AB_2684162" "unprognostic (1.46e-1)" "unprognostic (3.18e-3)" "unprognostic (1.06e-2)" "unprognostic (3.31e-2)" "unprognostic (3.90e-2)" "unprognostic (8.16e-2)" "unprognostic (4.25e-3)" "unprognostic (4.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (1.02e-1)" "unprognostic (3.93e-2)" "unprognostic (8.38e-5)" "unprognostic (5.02e-3)" PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 129.9;Kupffer cells: 84.8;Langerhans cells: 82.8;Macrophages: 124.2;monocytes: 429.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1664.4;non-classical monocyte: 1150.6" "Group enriched" "Detected in all" 5 "granulocytes: 1664.4;monocytes: 1150.6" "Cancer enhanced" "Detected in some" "Leukemia: 6.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" HPA056132 Approved "Secreted to blood" Receptor NA NA 1500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 2 "HPA056132: AB_2683048" "unprognostic (5.53e-2)" "prognostic favorable (2.99e-4)" "unprognostic (7.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.20e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.01e-3)" "unprognostic (9.95e-2)" "unprognostic (8.57e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.47e-2)" "unprognostic (3.17e-2)" "unprognostic (1.99e-1)" "unprognostic (4.80e-2)" PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367831 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 30.7;NK-cells: 57.1;Rod photoreceptor cells: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 251.7" "Group enriched" "Detected in all" 8 "granulocytes: 251.7;monocytes: 76.0" "Low cancer specificity" "Detected in all" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" Receptor NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 101.1;intestine: 85.1;lymphoid tissue: 160.0" "Cell type enriched" "Detected in many" 5 "Plasma cells: 671.7" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Myeloma: 827.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 2 Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457681-20461465 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 5 "HPA048528: AB_2680427" "unprognostic (1.84e-1)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (3.37e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.85e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.80e-2)" "unprognostic (1.47e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 77.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 77.2" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 57: Platelets - Hemostasis" 4 "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" PIRT ENSG00000233670 "Phosphoinositide interacting regulator of transient receptor potential channels" P0C851 17 10822470-10838087 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;intestine: 3.8" "Cell type enriched" "Detected in single" 4 "Astrocytes: 2.5" "Cancer enriched" "Detected in single" 40 "glioma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 51 "Neuroblastoma: 5.1" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042337 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" Cytosol "Plasma membrane" "HPA042337: AB_10794795" "unprognostic (2.95e-1)" "unprognostic (2.19e-2)" "unprognostic (7.57e-2)" "unprognostic (6.58e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (2.85e-3)" PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662221 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 220.5;Syncytiotrophoblasts: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 Cytosol "Golgi apparatus" "HPA031090: AB_10600114, HPA031091: AB_10600893" "unprognostic (7.96e-2)" "unprognostic (5.41e-3)" "unprognostic (2.60e-1)" "unprognostic (8.31e-2)" "unprognostic (5.61e-2)" "unprognostic (4.55e-3)" "unprognostic (2.44e-3)" "unprognostic (8.13e-3)" "unprognostic (6.37e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-2)" "unprognostic (4.18e-3)" "unprognostic (1.91e-2)" "unprognostic (4.85e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.27e-5)" PKD1 "PBP, Pc-1, TRPP1" ENSG00000008710 "Polycystin 1, transient receptor potential channel interacting" P98161 16 2088708-2135898 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 252.1" "Cell type enhanced" "Detected in all" "Excitatory neurons: 133.5;Horizontal cells: 85.6;Inhibitory neurons: 96.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046448 Approved NA NA 840000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "CAB046448: AB_2163360" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic favorable (3.35e-4)" "unprognostic (1.98e-2)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "prognostic favorable (3.38e-5)" "unprognostic (7.86e-2)" "unprognostic (4.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.78e-2)" "unprognostic (2.81e-1)" PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 12.7;Excitatory neurons: 24.8;Inhibitory neurons: 36.2;Late spermatids: 8.8;Microglial cells: 14.3;Oligodendrocyte precursor cells: 10.8;Oligodendrocytes: 15.9" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 20: Myeloma - Immune response" "Cluster 69: Neurons - Neuronal signaling" "HPA020422: AB_1855434, HPA022424: AB_1855435" "unprognostic (5.47e-2)" "unprognostic (5.33e-3)" "unprognostic (1.49e-2)" "unprognostic (9.74e-2)" "unprognostic (4.03e-2)" "unprognostic (6.31e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-4)" "unprognostic (1.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 124.7;Inhibitory neurons: 142.7;Microglial cells: 91.3;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 204.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 12 "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.7;retina: 12.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Early spermatids: 10.3;Hofbauer cells: 13.7;Horizontal cells: 19.5;Kupffer cells: 9.7;Late spermatids: 21.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;Uterine cancer: 1.0" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" PKD2L2 TRPP5 ENSG00000078795 "Polycystin 2 like 2, transient receptor potential cation channel" Q9NZM6 5 137887968-137942747 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Group enriched" "Detected in many" 4 "Early spermatids: 58.8;Spermatocytes: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041903, HPA043634" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Plasma membrane" Cytosol "HPA041903: AB_2677734, HPA043634: AB_2678591" "unprognostic (7.53e-3)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (3.59e-1)" "unprognostic (4.04e-1)" "unprognostic (1.21e-2)" "unprognostic (3.06e-1)" "unprognostic (1.40e-4)" "unprognostic (1.64e-2)" "unprognostic (2.13e-2)" "unprognostic (3.00e-2)" "unprognostic (5.85e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" PKDREJ ENSG00000130943 "Polycystin family receptor for egg jelly" Q9NTG1 22 46255663-46263343 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;Early spermatids: 3.8;Late spermatids: 1.3;Spermatocytes: 7.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" HPA034587 Enhanced NA NA "Cluster 21: Testis - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA034587: AB_10670570" "unprognostic (9.48e-3)" "unprognostic (1.09e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" "unprognostic (6.11e-2)" "unprognostic (5.06e-4)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (8.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-1)" "unprognostic (3.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.6;kidney: 13.2;pancreas: 9.1" "Group enriched" "Detected in some" 5 "Early spermatids: 370.0;Late spermatids: 97.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.1;Kidney cancer: 2.0" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" PKHD1L1 ENSG00000205038 "PKHD1 like 1" Q86WI1 8 109362461-109537207 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.6;thyroid gland: 66.7" "Cell type enhanced" "Detected in some" "Endothelial cells: 34.9;Glandular and luminal cells: 57.3;Lymphatic endothelial cells: 154.3;Mesothelial cells: 190.9;Plasma cells: 48.6;Secretory cells: 57.3" "Group enriched" "Detected in some" 18 "endometrial cancer: 5.2;ovarian cancer: 1.9;thyroid cancer: 3.8" "Region enhanced" "Detected in single" "choroid plexus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044458 Uncertain NA NA 13000000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA044458: AB_2678949" "unprognostic (9.07e-3)" "unprognostic (3.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.61e-4)" "unprognostic (5.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.91e-2)" "unprognostic (3.45e-2)" "unprognostic (3.31e-2)" "unprognostic (1.98e-1)" "unprognostic (9.65e-3)" "unprognostic (1.92e-1)" "unprognostic (7.76e-6)" "unprognostic (4.56e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-3)" "unprognostic (2.73e-2)" PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.3;testis: 55.3" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Erythroid cells: 29.1;Extravillous trophoblasts: 54.9;Plasma cells: 23.9;Spermatocytes: 113.3;Spermatogonia: 29.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 2 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 1 "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 103.4;Syncytiotrophoblasts: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 38000000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 58: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38214778 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid metabolism, Phospholipid metabolism" "Calmodulin-binding, Hydrolase" "Disease variant, Dystonia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.5;Spermatocytes: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Leukemia: 27.8" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000825, HPA001171" Approved Supported "Nuclear speckles,Plasma membrane,Microtubules" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 8 "Plasma membrane" "Nuclear speckles, Microtubules" "HPA000825: , HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favorable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favorable (1.55e-4)" PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 38.0;thyroid gland: 40.6" "Cell type enhanced" "Detected in many" "Serous glandular cells: 142.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" Receptor NA NA 960000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" PLAAT1 "A-C1, H-REV107, HRASLS, HRASLS1, PLA/AT1, PLAAT-1" ENSG00000127252 "Phospholipase A and acyltransferase 1" Q9HDD0 3 193241128-193277738 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 86.9;testis: 71.6;tongue: 42.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 117.2;Early spermatids: 585.3;Late spermatids: 225.7;Oligodendrocyte precursor cells: 91.0;Spermatocytes: 210.3" "Cancer enhanced" "Detected in many" "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051179 Uncertain Approved "Focal adhesion sites,Cytosol" No No "Cluster 4: Neutrophils - Degranulation" "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 7 "Focal adhesion sites" Cytosol "HPA051179: AB_2681375" "unprognostic (3.01e-2)" "unprognostic (4.21e-2)" "unprognostic (7.93e-3)" "unprognostic (4.82e-3)" "unprognostic (2.79e-1)" "unprognostic (1.87e-1)" "unprognostic (9.97e-3)" "unprognostic (9.68e-3)" "unprognostic (1.84e-1)" "unprognostic (3.55e-1)" "unprognostic (1.77e-4)" "unprognostic (5.09e-2)" "unprognostic (1.38e-5)" "unprognostic (1.61e-2)" "prognostic favorable (4.36e-4)" "unprognostic (2.98e-3)" "unprognostic (1.13e-2)" PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 65.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 78.8;Distal enterocytes: 73.3;Ionocytes: 52.3;Proximal enterocytes: 90.8;Proximal tubular cells: 152.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.4;naive B-cell: 8.3" "Lineage enriched" "Detected in many" 10 "B-cells: 17.4" "Cancer enhanced" "Detected in many" "Myeloma: 30.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" HPA058997 Approved Approved Mitochondria NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 307.6;brain: 309.1" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 421.1;Granulosa cells: 452.6;Proximal tubular cells: 661.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 188.1" "Group enriched" "Detected in all" 6 "dendritic cells: 188.1;T-cells: 55.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Approved Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 3 Mitochondria Cytosol "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 680.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 806.7;Langerhans cells: 2298.1;Macrophages: 885.5;monocytes: 3085.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1177.3" "Group enriched" "Detected in all" 4 "granulocytes: 1177.3;monocytes: 553.8" "Low cancer specificity" "Detected in all" "Thyroid - Neutrophils" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 4100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40389472 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 692.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 624.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1768.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1768.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Colon - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 41: Basophils - Unknown function" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 3 "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;brain: 15.6;lymphoid tissue: 11.0" "Cell type enriched" "Detected in some" 13 "dendritic cells: 694.5" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3628.5" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3628.5" "Group enriched" "Detected in some" 77 "Leukemia: 34.7;lymphoma: 37.2;Myeloma: 37.5" "Prostate - T-cells, Skin - Langerhans cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2900000 "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.4;choroid plexus: 26.8" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 305.8;Oligodendrocyte precursor cells: 119.8;Oligodendrocytes: 211.1" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Group enriched" "Detected in all" 9 "cerebellum: 34.9;choroid plexus: 117.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.9;Neuroblastoma: 4.9" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028389 Approved Mitochondria No No "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Mitochondria "HPA028389: AB_10602145" "unprognostic (5.20e-2)" "unprognostic (1.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (8.77e-2)" "unprognostic (4.36e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-5)" "unprognostic (2.79e-2)" "unprognostic (4.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.18e-1)" PLD6 Zuc ENSG00000179598 "Phospholipase D family member 6" Q8N2A8 17 17200995-17206333 "Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid degradation, Lipid metabolism, Meiosis, Spermatogenesis" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.6" "Cell type enhanced" "Detected in many" "Oocytes: 48.5;Spermatocytes: 30.6;Spermatogonia: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.8;NK-cells: 6.2;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA049345 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Testis - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA049345: AB_2680722" "unprognostic (1.71e-1)" "unprognostic (6.80e-3)" "unprognostic (3.21e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (7.83e-2)" "unprognostic (9.01e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (1.56e-1)" "unprognostic (3.51e-1)" "unprognostic (2.24e-1)" PLET1 C11orf34 ENSG00000188771 "Placenta expressed transcript 1" Q6UQ28 11 112248153-112260860 "Predicted membrane proteins" Differentiation "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.7;Inhibitory neurons: 1.9;Oligodendrocytes: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 2.3" HPA040237 Uncertain NA NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 51: Oligodendrocytes - Unknown function" "HPA040237: AB_10793960" "unprognostic (8.70e-2)" "unprognostic (1.75e-1)" "unprognostic (8.51e-3)" "unprognostic (5.19e-2)" PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 923.1;breast: 448.1" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 55.1" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 1 Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" PLLP "PMLP, TM4SF11" ENSG00000102934 Plasmolipin Q9Y342 16 57248547-57284672 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 200.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.1;Cholangiocytes: 166.0;Glandular and luminal cells: 144.8;Oligodendrocyte precursor cells: 131.6;Oligodendrocytes: 180.0;Proximal enterocytes: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "naive CD4 T-cell: 14.5;naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 8 "T-cells: 14.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 47.5" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041862 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 33 "HPA041862: AB_2677712" "unprognostic (7.96e-2)" "unprognostic (2.07e-3)" "unprognostic (3.86e-2)" "prognostic favorable (2.80e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (5.64e-2)" "unprognostic (6.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (6.21e-9)" "unprognostic (2.06e-2)" "unprognostic (9.06e-3)" "unprognostic (3.86e-1)" "unprognostic (3.32e-2)" PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 1507.8;skeletal muscle: 489.1" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 4136.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "skin cancer: 4.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005597, HPA026900" Enhanced NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 44 "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.59e-4)" PLOD2 "LH2, TLH" ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146035139-146163725 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 124.2;Extravillous trophoblasts: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 285.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 21000 "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 53 "brain: 10451.4" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 4489.2" "Group enriched" "Detected in many" 22 "glioma: 160.5;melanoma: 75.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "skin cancer: 239.8" "Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 2 "HPA004128: AB_1079635" "unprognostic (5.72e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-2)" "unprognostic (4.09e-3)" "unprognostic (1.32e-1)" "unprognostic (3.95e-2)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-5)" "unprognostic (4.91e-2)" "unprognostic (1.86e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-2)" PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 509.1;Suprabasal keratinocytes: 542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 58 "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 310.9;Leydig cells: 217.4;Prostatic glandular cells: 734.7" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 117.5" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 6 "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 102.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Ciliated cells: 211.6;Club cells: 236.1;Ductal cells: 340.4;Ionocytes: 251.4;Proximal enterocytes: 205.6;Rod photoreceptor cells: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.3;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 40 "T-cells: 6.6" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 354.8;Fibroblasts: 410.5;Leydig cells: 864.7;Peritubular cells: 305.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 65.5" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "brain: 3.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 29 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 288.3;Prostatic glandular cells: 182.3;Serous glandular cells: 193.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.7;memory B-cell: 212.7;naive B-cell: 307.0" "Group enriched" "Detected in all" 7 "B-cells: 307.0;granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid metabolism" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 73.8;Late spermatids: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Stomach - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 21: Early spermatids - Spermatogenesis" 44 "Nucleoplasm, Vesicles" Cytosol "HPA018096: AB_1855609" "unprognostic (2.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.03e-1)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (4.38e-2)" "unprognostic (6.95e-3)" "unprognostic (1.33e-1)" "unprognostic (5.26e-2)" "unprognostic (9.06e-2)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.99e-4)" "unprognostic (2.56e-1)" "unprognostic (2.28e-2)" "unprognostic (2.87e-2)" "unprognostic (5.88e-2)" PLPP7 "C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3" ENSG00000160539 "Phospholipid phosphatase 7 (inactive)" Q8NBV4 9 131289459-131359022 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 88.3;skeletal muscle: 202.7;tongue: 71.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.5;Cardiomyocytes: 46.7;Extravillous trophoblasts: 25.6;Horizontal cells: 15.1;Oocytes: 27.2;Skeletal myocytes: 49.8" "Cancer enhanced" "Detected in many" "glioma: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9;Rhabdoid: 5.8" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070252 Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" Vesicles Nucleoplasm "HPA070252: AB_2686242" "unprognostic (2.19e-1)" "unprognostic (3.07e-1)" "unprognostic (3.07e-2)" "unprognostic (2.71e-1)" "unprognostic (8.78e-2)" "unprognostic (7.03e-2)" "unprognostic (1.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.65e-1)" "unprognostic (3.96e-3)" "unprognostic (1.47e-1)" "unprognostic (1.71e-3)" "unprognostic (3.69e-2)" "unprognostic (1.10e-2)" "unprognostic (7.85e-2)" "unprognostic (9.72e-3)" PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.7;kidney: 15.1" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 602.8;Oligodendrocytes: 253.7" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 13 Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 71.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 71.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048973, HPA077966" Approved Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" 20 Nucleoplasm "HPA048973: AB_2680580, HPA077966: " "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (7.10e-2)" "unprognostic (1.37e-1)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.82e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.46e-11)" "unprognostic (1.99e-2)" "unprognostic (1.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.17e-1)" PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;brain: 40.8;fallopian tube: 10.8" "Cell type enriched" "Detected in some" 7 "Ciliated cells: 50.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 29.8;Neuroblastoma: 20.8" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 42: Ciliated cells - Cilium assembly" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" PLPPR5 "LPPR5, PAP2, PAP2D, PRG5" ENSG00000117598 "Phospholipid phosphatase related 5" Q32ZL2 1 98890245-99227929 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;retina: 1.6;testis: 2.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 54.5;Inhibitory neurons: 131.0;Oligodendrocyte precursor cells: 135.8" "Group enriched" "Detected in some" 13 "glioma: 2.7;renal cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 12.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018072, HPA059085" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" Cytosol "HPA018072: AB_1854958, HPA059085: AB_2732631" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.22e-4)" "unprognostic (1.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" PLSCR3 ENSG00000187838 "Phospholipid scramblase 3" Q9NRY6 17 7389727-7394842 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 5.8;Basal squamous epithelial cells: 16.0;Schwann cells: 12.3;Squamous epithelial cells: 10.7;T-cells: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048387, HPA068609" Supported Supported Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: T-cells - T-cell receptor" 26 Mitochondria "HPA048387: AB_2680381, HPA068609: AB_2686011" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (2.29e-2)" "unprognostic (1.56e-2)" "unprognostic (4.36e-2)" "unprognostic (5.02e-2)" "unprognostic (2.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-5)" "unprognostic (1.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (2.55e-2)" PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Astrocytes: 143.4;Endothelial cells: 76.4;Lymphatic endothelial cells: 134.7;Schwann cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 45 "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" PLSCR5 ENSG00000231213 "Phospholipid scramblase family member 5" A0PG75 3 146576555-146605346 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Inhibitory neurons: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.5;testis cancer: 1.5" "Region enhanced" "Detected in single" "midbrain: 1.0" "Low region specificity" "Detected in many" HPA047249 Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA047249: AB_2679997" PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 423.1" "Group enriched" "Detected in many" 12 "Adipocytes: 454.6;Endothelial cells: 397.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 35.1" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Group enriched" "Detected in some" 15 "Leukemia: 10.7;lymphoma: 3.9;ovarian cancer: 6.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 272.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 13.9" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012805 Approved "Intracellular and membrane" "No annotated function" NA NA 17000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "HPA012805: AB_1857893" "unprognostic (4.28e-1)" "unprognostic (3.55e-1)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (6.07e-3)" "unprognostic (4.62e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (9.15e-8)" "unprognostic (9.37e-3)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1440.4;Oligodendrocytes: 437.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.6;intermediate monocyte: 33.4;myeloid DC: 36.1;neutrophil: 81.8;non-classical monocyte: 37.5" "Group enriched" "Detected in many" 13 "dendritic cells: 36.1;granulocytes: 81.8;monocytes: 57.6" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" PLXNA1 "NOV, PLXN1" ENSG00000114554 "Plexin A1" Q9UIW2 3 126982693-127037389 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 1: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007499, CAB012483" Uncertain Supported Nucleoplasm,Cytosol NA NA 10000000 "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" Nucleoplasm Cytosol "CAB012483: , HPA007499: AB_1079637" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (4.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.79e-2)" "unprognostic (9.06e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (3.77e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.64e-5)" "unprognostic (4.50e-3)" "unprognostic (7.62e-3)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 33.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 68.6;Astrocytes: 95.4;Excitatory neurons: 130.3;Horizontal cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 1400000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 34: Neurons - Neuronal signaling" "CAB009763: AB_2166388" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (8.85e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-2)" "unprognostic (4.84e-2)" "unprognostic (6.88e-3)" "unprognostic (7.06e-2)" "unprognostic (2.61e-1)" "unprognostic (8.41e-2)" "unprognostic (4.49e-3)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" PLXNA3 "6.3, Plxn3, PLXN4, SEX, XAP-6" ENSG00000130827 "Plexin A3" P51805 X 154458281-154477779 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000915 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 94000 "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Non-specific - Transcription" 1 "Golgi apparatus, Cytosol" "Plasma membrane" "HPA000915: " "unprognostic (2.79e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-3)" "unprognostic (8.04e-3)" "unprognostic (1.63e-1)" "unprognostic (9.05e-3)" "unprognostic (1.06e-2)" "unprognostic (2.25e-1)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.05e-1)" "unprognostic (4.10e-2)" "unprognostic (1.38e-3)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123340-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.3" "Cell type enhanced" "Detected in many" "dendritic cells: 64.2;Excitatory neurons: 227.5;Inhibitory neurons: 251.3;Oligodendrocyte precursor cells: 48.6" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" PLXNB1 "KIAA0407, PLXN5, SEP" ENSG00000164050 "Plexin B1" O43157 3 48403854-48430086 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.9;Oligodendrocytes: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040586 Enhanced "Intracellular and membrane" Receptor NA NA 95000000 "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" 5 "HPA040586: AB_10794034" "unprognostic (1.31e-3)" "unprognostic (7.09e-2)" "unprognostic (9.63e-2)" "unprognostic (8.13e-2)" "unprognostic (3.65e-1)" "prognostic favorable (5.03e-4)" "unprognostic (1.06e-1)" "unprognostic (4.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.01e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-2)" "prognostic favorable (2.77e-5)" "unprognostic (4.01e-2)" "unprognostic (1.61e-1)" "unprognostic (6.98e-2)" "prognostic favorable (7.60e-4)" PLXNB2 "KIAA0315, MM1, PLEXB2" ENSG00000196576 "Plexin B2" O15031 22 50274979-50307646 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 258.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "classical monocyte: 11.1;intermediate monocyte: 16.4;myeloid DC: 8.3;non-classical monocyte: 21.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 25 "dendritic cells: 8.3;monocytes: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003100 Uncertain NA NA 78000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 35: Respiratory epithelial cells - Unknown function" 5 "HPA003100: AB_1079638" "unprognostic (4.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.28e-2)" "unprognostic (4.96e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (8.47e-3)" "unprognostic (9.84e-2)" "unprognostic (3.05e-2)" "prognostic favorable (4.75e-4)" "unprognostic (1.61e-2)" "unprognostic (9.41e-3)" "unprognostic (6.05e-2)" PLXNB3 "PLEXB3, PLEXR, PLXN6" ENSG00000198753 "Plexin B3" Q9ULL4 X 153764196-153779346 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;intestine: 55.3" "Group enriched" "Detected in some" 5 "Astrocytes: 41.5;Oligodendrocytes: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 52.1" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048046 Enhanced NA NA 390000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Astrocytes - Unknown function" 2 "HPA048046: AB_2680239" "prognostic unfavorable (6.13e-4)" "unprognostic (2.60e-1)" "unprognostic (9.10e-4)" "unprognostic (2.30e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-3)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.66e-1)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (9.73e-3)" "unprognostic (1.98e-2)" PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 54.8;Macrophages: 64.7;Melanocytes: 166.6;monocytes: 119.2" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Group enriched" "Detected in all" 4 "granulocytes: 16.5;monocytes: 8.7" "Cancer enhanced" "Detected in many" "Myeloma: 34.9;skin cancer: 21.8" "Skin - Melanocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 74: Neutrophils - Degranulation" 1 Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Endothelial cells: 94.1;Hofbauer cells: 78.0;Kupffer cells: 117.0;Lymphatic endothelial cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 30: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" PMEL "D12S53E, gp100, HMB-45, HMB45, ME20, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 78.0;endometrium 1: 31.2;skin 1: 112.3" "Cell type enriched" "Detected in many" 61 "Melanocytes: 2210.9" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 49 "skin cancer: 3389.1" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" Other NA NA 11000000 "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 287.9;dendritic cells: 258.7;Ductal cells: 322.4;Muller glia cells: 312.7;Prostatic glandular cells: 636.7" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218269651-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 457.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" PNLDC1 "dJ195P10.2, FLJ40240, Trimmer" ENSG00000146453 "PARN like ribonuclease domain containing exonuclease 1" Q8NA58 6 159800249-159820704 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;testis: 7.9" "Cell type enriched" "Detected in some" 8 "Oocytes: 200.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.2" "Region enhanced" "Detected in many" "cerebral cortex: 16.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.5;Sarcoma: 2.0" "Pancreas - Ductal cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052026 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 44: Oocytes - Unknown function" "HPA052026: AB_2681699" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Intellectual disability, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 100.8;Oocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007522, HPA064773" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA007522: AB_1079649, HPA064773: " "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (3.23e-2)" "unprognostic (2.78e-1)" "prognostic favorable (5.25e-4)" "unprognostic (3.53e-3)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.36e-1)" "prognostic favorable (7.53e-4)" "unprognostic (3.10e-3)" "unprognostic (3.50e-1)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" PNPLA7 "C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2" ENSG00000130653 "Patatin like phospholipase domain containing 7" Q6ZV29 9 137459952-137550402 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 53.3;Excitatory neurons: 22.8;Inhibitory neurons: 20.6;Oligodendrocytes: 19.5" "Cancer enhanced" "Detected in many" "prostate cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.0;T-reg: 1.2" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 1.2" "Cancer enhanced" "Detected in some" "prostate cancer: 5.4" "Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009130 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 18: Non-specific - Ribosome" "Cluster 34: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Astrocytes - Unknown function" Cytosol "Centriolar satellite" "HPA009130: AB_2268411" "unprognostic (1.49e-1)" "unprognostic (1.40e-2)" "unprognostic (3.61e-3)" "unprognostic (2.38e-2)" "unprognostic (3.68e-2)" "unprognostic (6.69e-3)" "unprognostic (2.72e-3)" "unprognostic (5.14e-4)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "prognostic favorable (2.24e-5)" "unprognostic (1.09e-1)" "unprognostic (2.23e-3)" "unprognostic (2.42e-1)" "unprognostic (6.80e-2)" "unprognostic (8.81e-2)" "unprognostic (3.45e-3)" PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470417-108569666 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 29: Monocytes - Innate immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" PODXL "gp135, Gp200, PC, PCLP, PDX, PODXL1" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 92.8" "Cell type enhanced" "Detected in many" "Adipocytes: 149.4;Endothelial cells: 185.3;Glandular and luminal cells: 99.2;Microglial cells: 88.6;Rod photoreceptor cells: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 5 "testis cancer: 590.4" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" PODXL2 "endoglycan, PODLX2" ENSG00000114631 "Podocalyxin like 2" Q9NZ53 3 127629185-127672802 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.6;pituitary gland: 57.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 88.6;Cone photoreceptor cells: 74.8;Early spermatids: 86.0;Horizontal cells: 83.1;Late spermatids: 145.1;Spermatogonia: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024934, HPA042265" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "CAB024934: , HPA042265: AB_2677920" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (7.02e-2)" "unprognostic (1.07e-2)" "unprognostic (9.74e-2)" "unprognostic (1.79e-2)" "unprognostic (8.97e-3)" "unprognostic (1.81e-1)" "unprognostic (3.89e-1)" "unprognostic (2.67e-1)" "unprognostic (4.05e-3)" "unprognostic (3.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.67e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-3)" POLR1E "FLJ13390, FLJ13970, PAF53, PRAF1, RPA49" ENSG00000137054 "RNA polymerase I subunit E" Q9GZS1 9 37485948-37503697 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022527, HPA052400" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 62: Connective tissue - ECM organization" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Nucleoli fibrillar center" "HPA022527: AB_1854924, HPA052400: AB_2681815" "prognostic favorable (2.27e-4)" "unprognostic (2.09e-1)" "unprognostic (9.90e-3)" "unprognostic (1.10e-2)" "unprognostic (7.16e-3)" "unprognostic (2.07e-1)" "unprognostic (1.09e-2)" "unprognostic (7.14e-2)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.80e-1)" "unprognostic (2.48e-1)" "unprognostic (1.07e-1)" "unprognostic (4.96e-2)" "unprognostic (5.23e-1)" "unprognostic (1.58e-1)" "unprognostic (4.24e-2)" POMGNT1 "FLJ20277, LGMD2O, MEB, MGAT1.2" ENSG00000085998 "Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)" Q8WZA1 1 46188683-46220305 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044518 Approved NA NA 17000000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 6 "HPA044518: AB_10795985" "unprognostic (4.59e-3)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (3.20e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.82e-1)" "unprognostic (5.74e-2)" "unprognostic (5.37e-2)" "prognostic favorable (4.27e-4)" "unprognostic (5.86e-2)" "unprognostic (4.39e-2)" "unprognostic (4.99e-3)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" POMK "FLJ23356, SgK196" ENSG00000185900 "Protein O-mannose kinase" Q9H5K3 8 43093498-43131180 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 28: Dendritic cells - Antigen presentation" 7 "HPA013321: AB_2668809" "unprognostic (1.66e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (4.37e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.10e-2)" POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502789-131523806 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 64.1;Spermatocytes: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065252 Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Golgi apparatus" "HPA065252: AB_2685445" "unprognostic (2.00e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (5.09e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (5.35e-3)" "unprognostic (1.14e-1)" "unprognostic (9.76e-3)" "unprognostic (2.84e-1)" "prognostic favorable (3.90e-5)" "unprognostic (8.36e-2)" "prognostic favorable (4.68e-5)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-1)" POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320883 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 25.7;Oligodendrocytes: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 78: Testis - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm "Nucleoli, Cytosol" "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 392.2" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 245.9;Skeletal myocytes: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Neuroblastoma: 4.5;testis cancer: 2.3" "Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA024255 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" POPDC3 "bA355M14.1, MGC22671, POP3" ENSG00000132429 "Popeye domain containing 3" Q9HBV1 6 105157900-105180014 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 22.2;skeletal muscle: 92.8;tongue: 28.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 57.3;Early spermatids: 84.4;Late spermatids: 34.0;Oocytes: 27.9;Pancreatic endocrine cells: 18.7;Skeletal myocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Prostate - Smooth muscle cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012514 Approved Nucleoli,Cytosol NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 21: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA012514: " "unprognostic (2.17e-1)" "unprognostic (2.15e-2)" "unprognostic (3.65e-1)" "unprognostic (1.14e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.79e-4)" "unprognostic (2.81e-1)" "unprognostic (1.69e-1)" "unprognostic (5.12e-3)" "unprognostic (2.37e-1)" "unprognostic (2.83e-9)" "unprognostic (6.25e-2)" "unprognostic (1.24e-1)" "unprognostic (3.75e-3)" "unprognostic (1.33e-2)" POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 303.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 416.2;Ionocytes: 315.1;Proximal enterocytes: 277.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 Vesicles "Nucleoplasm, Cytosol" "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508959-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 36.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Club cells: 29.4;Ionocytes: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" PPAN-P2RY11 ENSG00000243207 "PPAN-P2RY11 readthrough" 19 10106223-10114780 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 6 "B-cells: 9.2;Basal squamous epithelial cells: 13.3;Erythroid cells: 8.6;Gastric mucus-secreting cells: 11.8;Plasma cells: 8.6;Squamous epithelial cells: 17.5;T-cells: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA014232 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "HPA014232: AB_1854883" "unprognostic (4.81e-1)" "unprognostic (5.85e-2)" "unprognostic (3.18e-1)" "unprognostic (3.11e-2)" "unprognostic (3.54e-1)" "unprognostic (1.61e-1)" "unprognostic (4.85e-2)" "unprognostic (2.01e-1)" "unprognostic (5.27e-3)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (2.23e-1)" "unprognostic (9.20e-2)" "unprognostic (5.85e-3)" "unprognostic (2.34e-1)" PPFIA1 "LIP.1, LIPRIN" ENSG00000131626 "PTPRF interacting protein alpha 1" Q13136 11 70270690-70385312 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017032, HPA042271" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 11 Cytosol "Focal adhesion sites" "CAB017032: , HPA042271: AB_2677923" "unprognostic (1.89e-1)" "unprognostic (1.28e-2)" "unprognostic (6.27e-2)" "unprognostic (9.92e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.58e-4)" "unprognostic (7.20e-3)" "unprognostic (2.20e-1)" "unprognostic (3.02e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (8.26e-4)" "unprognostic (1.14e-1)" "prognostic favorable (3.76e-4)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (2.14e-2)" PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 120000 "Cluster 41: Basophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 2 Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" PPM1L PP2CE ENSG00000163590 "Protein phosphatase, Mg2+/Mn2+ dependent 1L" Q5SGD2 3 160755602-161078902 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 120.1;Excitatory neurons: 333.0;Inhibitory neurons: 168.3;Oligodendrocyte precursor cells: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019891, HPA019953" Approved Approved Nucleoplasm,Cytosol NA NA 26000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA019891: AB_1855631, HPA019953: AB_2170360" "prognostic unfavorable (4.90e-4)" "unprognostic (7.29e-3)" "unprognostic (2.01e-1)" "unprognostic (2.59e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-2)" "unprognostic (2.49e-2)" "unprognostic (1.92e-1)" "unprognostic (4.51e-2)" "unprognostic (7.51e-2)" "unprognostic (2.69e-3)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (9.13e-3)" "unprognostic (2.07e-1)" PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 64 "heart muscle: 39.4;skeletal muscle: 147.4;tongue: 100.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 227.0;Skeletal myocytes: 194.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 12 "thalamus: 1.1" "Not detected" "Not detected" "HPA070440, HPA073138" Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 23: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA070440: , HPA073138: " "unprognostic (8.96e-3)" PPP1R3F Hb2E ENSG00000049769 "Protein phosphatase 1 regulatory subunit 3F" Q6ZSY5 X 49269793-49301461 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;skeletal muscle: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.1;Horizontal cells: 32.7;Oligodendrocytes: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.4" "Lineage enriched" "Detected in single" 12 "T-cells: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000244, HPA000918, HPA075936" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000244: AB_2665949, HPA000918: AB_2268692, HPA075936: " "unprognostic (6.69e-2)" "unprognostic (2.87e-2)" "unprognostic (4.98e-4)" "unprognostic (1.83e-2)" "unprognostic (6.48e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-1)" "unprognostic (5.17e-2)" "unprognostic (1.91e-2)" "unprognostic (2.89e-1)" "prognostic favorable (1.85e-6)" "unprognostic (5.99e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (2.76e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-1)" PRAF2 "JM4, Yip6a" ENSG00000243279 "PRA1 domain family member 2" O60831 X 49071161-49074002 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 159.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "HPA002859, HPA005504, CAB011655" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 50: Connective tissue cells - ECM organization" 26 "Endoplasmic reticulum" Vesicles "CAB011655: , HPA002859: AB_1079672, HPA005504: AB_2667340" "unprognostic (1.50e-1)" "prognostic favorable (7.42e-4)" "unprognostic (1.17e-2)" "unprognostic (1.32e-2)" "unprognostic (4.29e-1)" "unprognostic (3.67e-1)" "prognostic unfavorable (1.66e-6)" "prognostic favorable (2.81e-4)" "unprognostic (6.10e-2)" "unprognostic (3.77e-1)" "prognostic favorable (4.88e-6)" "unprognostic (8.39e-3)" "prognostic unfavorable (5.83e-6)" "unprognostic (4.96e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 107.4;Syncytiotrophoblasts: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Endoplasmic reticulum" "HPA013582: AB_1855694, HPA014133: AB_1855695" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.96e-3)" "unprognostic (1.44e-1)" "unprognostic (9.89e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.33e-3)" "unprognostic (5.13e-2)" "unprognostic (4.14e-2)" "unprognostic (5.25e-2)" "unprognostic (1.28e-2)" PRIMA1 PRIMA ENSG00000175785 "Proline rich membrane anchor 1" Q86XR5 14 93718298-93788485 "Predicted membrane proteins" "Neurotransmitter degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.5;intestine: 51.9" "Group enriched" "Detected in some" 9 "Muller glia cells: 34.0;Oligodendrocytes: 50.9;Schwann cells: 120.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 6.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells" "Region enhanced" "Detected in many" "basal ganglia: 18.2" "Low region specificity" "Detected in all" "HPA046671, HPA060047" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" "Nucleoli, Cytosol" "HPA046671: AB_2679744, HPA060047: AB_2684194" "unprognostic (3.60e-2)" "unprognostic (1.97e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.03e-2)" "unprognostic (3.73e-2)" "unprognostic (1.07e-1)" "unprognostic (5.81e-2)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (8.94e-2)" "unprognostic (6.61e-3)" "prognostic unfavorable (2.62e-7)" "unprognostic (2.33e-2)" "unprognostic (2.67e-1)" "unprognostic (7.94e-4)" "unprognostic (4.57e-3)" PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645314-56715335 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.4;skeletal muscle: 37.2;tongue: 35.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 486.4;Excitatory neurons: 105.7;Inhibitory neurons: 114.1;Rod photoreceptor cells: 124.8;Skeletal myocytes: 222.5" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 68: Cardiomyocytes - Muscle contraction" 78 "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" PRLHR "GPR10, PrRPR" ENSG00000119973 "Prolactin releasing hormone receptor" P49683 10 118589997-118595648 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.0;pituitary gland: 6.8;smooth muscle: 3.3" "Group enriched" "Detected in some" 4 "Horizontal cells: 2.5;Inhibitory neurons: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5;prostate cancer: 1.4" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" HPA039361 Enhanced NA NA "Cluster 64: Neuronal - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA039361: AB_10673527" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" PRND "dJ1068H6.4, DOPPEL, DPL, PrPLP" ENSG00000171864 "Prion like protein doppel" Q9UKY0 20 4721909-4728460 "Predicted membrane proteins, Transporters" Fertilization Prion "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "choroid plexus: 39.4;testis: 68.8" "Cell type enriched" "Detected in some" 10 "Sertoli cells: 144.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Region enriched" "Detected in many" 24 "choroid plexus: 67.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 4.9" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043373 Enhanced NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" "HPA043373: AB_2678450" "unprognostic (1.69e-1)" "unprognostic (3.66e-2)" "unprognostic (2.24e-2)" "unprognostic (8.46e-2)" "unprognostic (3.40e-2)" "unprognostic (3.47e-3)" "unprognostic (3.01e-1)" "unprognostic (6.41e-2)" "unprognostic (2.00e-2)" "unprognostic (1.56e-1)" "unprognostic (3.10e-1)" "unprognostic (5.85e-2)" "unprognostic (2.02e-3)" "unprognostic (6.11e-2)" "unprognostic (2.86e-1)" "unprognostic (2.45e-2)" "unprognostic (1.63e-3)" PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 494.3" "Cell type enhanced" "Detected in all" "monocytes: 457.0;Schwann cells: 409.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 879.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 879.6" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 17 "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" PROCR "CCD41, CD201, EPCR" ENSG00000101000 "Protein C receptor" Q9UNN8 20 35172072-35216240 "Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.7" "Cell type enriched" "Detected in many" 4 "Mesothelial cells: 659.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 14.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039461 Enhanced NA NA 980000000 "Cluster 33: Non-specific - ATP binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 53: Fibroblasts - ECM organization" 1 "HPA039461: AB_10673359" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (4.69e-2)" "unprognostic (4.69e-2)" "unprognostic (1.84e-1)" "unprognostic (1.52e-1)" "unprognostic (4.76e-2)" "unprognostic (5.22e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.62e-6)" "unprognostic (3.37e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" PROKR1 "GPR73, GPR73a, PKR1, ZAQ" ENSG00000169618 "Prokineticin receptor 1" Q8TCW9 2 68643579-68658251 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.6;adrenal gland: 1.1;epididymis: 3.5" "Cell type enhanced" "Detected in single" "Adipocytes: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 3.4;Neuroblastoma: 1.2" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in many" "spinal cord: 9.0" HPA029396 Uncertain NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA029396: AB_10610285" "unprognostic (5.46e-2)" "unprognostic (1.60e-2)" "unprognostic (8.75e-2)" "unprognostic (4.99e-4)" "unprognostic (1.18e-1)" "unprognostic (2.55e-3)" "unprognostic (1.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.85e-1)" "unprognostic (4.52e-2)" "unprognostic (1.89e-1)" "unprognostic (9.72e-2)" "unprognostic (8.96e-7)" "unprognostic (4.07e-2)" "unprognostic (2.53e-1)" "unprognostic (4.19e-1)" "unprognostic (7.22e-2)" PROKR2 "dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2" ENSG00000101292 "Prokineticin receptor 2" Q8NFJ6 20 5299218-5316954 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Cone photoreceptor cells: 1.7;Early spermatids: 2.2;Granulosa cells: 2.8;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 17.0" "Low region specificity" "Detected in all" HPA047281 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 5 "HPA047281: AB_10960057" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 264.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 300.7;Mucus glandular cells: 169.5;Rod photoreceptor cells: 329.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 32.2" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004922, CAB011525, HPA031053, CAB080375, CAB080376" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 1 "CAB011525: AB_470302, CAB080375: , CAB080376: , HPA004922: AB_1846238, HPA031053: AB_2673713" "unprognostic (6.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-1)" "unprognostic (2.39e-1)" "unprognostic (6.64e-2)" "unprognostic (2.18e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (9.06e-2)" "prognostic favorable (2.56e-5)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (9.38e-2)" "unprognostic (1.17e-1)" PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.6;skin 1: 58.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 38.2;Club cells: 52.5;Ionocytes: 49.3;Squamous epithelial cells: 39.8;Suprabasal keratinocytes: 50.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 80.1;head and neck cancer: 80.5" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "retina: 621.9" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 270.2;Rod photoreceptor cells: 443.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5;Sarcoma: 1.5" "Prostate - Fibroblasts" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 2 "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" PRPS1 "CMTX5, DFN2, DFNX1, PPRibP, PRS-I" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 320000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 79 Vesicles "HPA043760: AB_2678656, HPA051269: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" PRRC1 FLJ32875 ENSG00000164244 "Proline rich coiled-coil 1" Q96M27 5 127517640-127555085 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039212 Supported Approved Vesicles NA NA 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 Vesicles "HPA039212: AB_10794634" "prognostic unfavorable (9.35e-5)" "unprognostic (9.01e-2)" "unprognostic (5.26e-3)" "unprognostic (6.36e-2)" "unprognostic (2.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-3)" "unprognostic (5.53e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (2.19e-1)" PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" 1 "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 27.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" PRRG3 TMG3 ENSG00000130032 "Proline rich and Gla domain 3" Q9BZD7 X 151694607-151705924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.2;epididymis: 7.2" "Cell type enriched" "Detected in some" 24 "Cardiomyocytes: 547.7" "Cancer enhanced" "Detected in some" "stomach cancer: 1.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "testis cancer: 2.4;thyroid cancer: 1.5" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060566 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA060566: AB_2684321" "unprognostic (1.85e-1)" "unprognostic (1.21e-1)" "unprognostic (7.71e-2)" "unprognostic (1.77e-2)" "unprognostic (4.42e-4)" "unprognostic (7.24e-2)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (2.06e-2)" "unprognostic (5.11e-2)" "unprognostic (3.01e-2)" "unprognostic (2.26e-1)" "unprognostic (1.98e-2)" "unprognostic (7.69e-2)" "unprognostic (4.64e-2)" "unprognostic (1.57e-1)" "unprognostic (1.84e-2)" PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.1;Basal squamous epithelial cells: 126.5;Squamous epithelial cells: 146.7;Suprabasal keratinocytes: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 5 "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 68.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 45.4;Excitatory neurons: 12.2;Horizontal cells: 17.0;Ovarian stromal cells: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA055149: AB_2682717, HPA059099: AB_2732632" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (2.10e-3)" "unprognostic (3.87e-3)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (5.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (8.08e-5)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 365.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 73.7;Horizontal cells: 64.2;Leydig cells: 36.5;Ovarian stromal cells: 53.0;Peritubular cells: 41.4;Rod photoreceptor cells: 42.8" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.5" "Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 6: Ovarian stromal cells - Transcription" 6 "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9939450-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 14.4;choroid plexus: 7.2;fallopian tube: 7.3;parathyroid gland: 14.7;pituitary gland: 10.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 22.7;Rod photoreceptor cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 83000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 55: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA035127: AB_10602822, HPA035128: AB_2674482, HPA069859: " "unprognostic (1.55e-1)" "unprognostic (8.41e-2)" "unprognostic (3.42e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-4)" "unprognostic (2.27e-3)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (2.20e-3)" "unprognostic (3.60e-1)" "unprognostic (1.01e-4)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (2.09e-1)" PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361690 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 15.7;bone marrow: 57.0" "Group enriched" "Detected in some" 10 "Horizontal cells: 19.5;Inhibitory neurons: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 27.0;Neuroblastoma: 70.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Neutrophil_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277161-151291862 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.1;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 3.4;Spermatocytes: 4.1;Spermatogonia: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053801: AB_2682267" "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" PRSS8 CAP1 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.3;Extravillous trophoblasts: 770.7;Proximal enterocytes: 331.5;Syncytiotrophoblasts: 632.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 5.0;choroid plexus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in some" HPA030436 Uncertain "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.1;thyroid gland: 10.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.9;Cone photoreceptor cells: 91.8;Oligodendrocyte precursor cells: 48.6;Rod photoreceptor cells: 76.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 15 "testis cancer: 159.2" "Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 106.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 855.1" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 50.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017269, HPA022470, HPA031079" Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 13 Cytosol "HPA017269: , HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 391.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 389.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "plasmacytoid DC: 166.4" "Lineage enriched" "Detected in all" 10 "dendritic cells: 166.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" PSCA lncPSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 2937.1" "Group enriched" "Detected in many" 5 "Club cells: 1987.4;Gastric mucus-secreting cells: 4643.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 205.3" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 50.6" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 48: Stomach - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "monocytes: 186.7;Oligodendrocytes: 368.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" 18 "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" PSENEN PEN2 ENSG00000205155 "Presenilin enhancer, gamma-secretase subunit" Q9NZ42 19 35745600-35747519 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 329.6" "Cell type enhanced" "Detected in all" "Ciliated cells: 627.0;Ionocytes: 301.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047435 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 10 "HPA047435: AB_2680047" "unprognostic (1.96e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (2.79e-1)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "unprognostic (1.41e-1)" "unprognostic (3.51e-3)" "unprognostic (2.30e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.70e-4)" "unprognostic (6.85e-2)" "unprognostic (1.80e-1)" "unprognostic (2.10e-1)" "unprognostic (5.41e-3)" PSG9 "PSG11, PSGII" ENSG00000183668 "Pregnancy specific beta-1-glycoprotein 9" Q00887 19 43211791-43269530 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 136 "placenta: 103.4" "Cell type enriched" "Detected in some" 25 "Syncytiotrophoblasts: 219.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 6.6;breast cancer: 22.3;liver cancer: 7.5;Rhabdoid: 26.1;testis cancer: 9.8" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 43000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (9.32e-2)" "unprognostic (3.28e-1)" "unprognostic (2.15e-1)" PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893254-67929676 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Non-specific - DNA binding" 1 "Nuclear speckles, Cytosol" "HPA053927: AB_2682312, HPA062763: " "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favorable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86047109-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "retina: 2.4" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 34.0;Rod photoreceptor cells: 8.7" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 76: Retina - Visual perception" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Photoreceptor cells - Visual perception" 3 Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 276.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 6 Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" PSMD2 "MGC14274, P97, Rpn1, S2, TRAP2" ENSG00000175166 "Proteasome 26S subunit ubiquitin receptor, non-ATPase 2" Q13200 3 184299198-184309050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 321.1" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 317.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045192, HPA062363" Enhanced NA NA 430000 "Cluster 25: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 15: Non-specific - Mixed function" 25 "HPA045192: AB_10961324, HPA062363: " "unprognostic (1.06e-2)" "unprognostic (1.69e-2)" "unprognostic (6.82e-2)" "unprognostic (2.43e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (9.98e-4)" "prognostic unfavorable (6.63e-7)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.69e-1)" "unprognostic (4.68e-2)" "unprognostic (1.51e-2)" "unprognostic (1.32e-1)" "unprognostic (4.25e-3)" "unprognostic (1.53e-1)" "unprognostic (9.12e-2)" "unprognostic (1.13e-2)" "unprognostic (2.74e-3)" PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 36.4;granulocytes: 74.7;Hofbauer cells: 76.0;Ionocytes: 32.0;Kupffer cells: 83.2;Langerhans cells: 86.2;Macrophages: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.9;eosinophil: 908.6;neutrophil: 749.9" "Group enriched" "Detected in many" 5 "granulocytes: 908.6;monocytes: 256.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 22.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.5" "Cell type enhanced" "Detected in many" "Late spermatids: 256.3;Leydig cells: 182.9;Peritubular cells: 418.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.2" "Lineage enriched" "Detected in single" 9 "T-cells: 6.2" "Low cancer specificity" "Detected in all" "Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 2 "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 57.2;salivary gland: 73.3" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 26.2;Leydig cells: 110.4;Peritubular cells: 68.5;Serous glandular cells: 33.0" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Peritubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" PTCHD1 FLJ30296 ENSG00000165186 "Patched domain containing 1" Q96NR3 X 23334849-23404374 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.9;intestine: 6.0" "Cell type enhanced" "Detected in some" "Astrocytes: 32.8;Breast glandular cells: 9.7;Excitatory neurons: 21.2;Horizontal cells: 16.4;Inhibitory neurons: 7.2;Mucus glandular cells: 7.8" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.0;Rhabdoid: 1.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046110 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA046110: AB_2679541" "unprognostic (1.50e-2)" "unprognostic (1.36e-2)" "unprognostic (7.43e-3)" "unprognostic (1.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (1.14e-4)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" "unprognostic (2.78e-1)" "unprognostic (2.13e-1)" "unprognostic (3.50e-1)" "unprognostic (3.19e-2)" "unprognostic (3.68e-4)" "unprognostic (5.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" PTCHD4 "C6orf138, dJ402H5.2, FLJ41841, PTCH53" ENSG00000244694 "Patched domain containing 4" Q6ZW05 6 47856673-48111197 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 458.2" "Group enriched" "Detected in some" 6 "melanoma: 1.1;renal cancer: 1.6;thyroid cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041276 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" "Plasma membrane, Cytosol" "HPA041276: AB_10796570" "unprognostic (1.35e-4)" "unprognostic (1.66e-2)" "unprognostic (3.25e-1)" "unprognostic (3.11e-3)" "unprognostic (1.07e-2)" "unprognostic (1.57e-3)" "unprognostic (7.94e-2)" "unprognostic (3.59e-3)" "unprognostic (2.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.49e-6)" "unprognostic (5.03e-4)" "unprognostic (9.84e-2)" "unprognostic (1.57e-2)" "unprognostic (5.56e-3)" PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" PTDSS2 PSS2 ENSG00000174915 "Phosphatidylserine synthase 2" Q9BVG9 11 448268-491399 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 139.5;Late spermatids: 335.5;Spermatocytes: 86.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038928, HPA038929" Approved NA NA "Cluster 78: Testis - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 1 "HPA038928: AB_10672832, HPA038929: AB_2676274" "unprognostic (3.41e-1)" "unprognostic (2.52e-1)" "unprognostic (2.07e-1)" "unprognostic (5.75e-3)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.12e-9)" "unprognostic (6.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-2)" "unprognostic (1.41e-3)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.39e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" "Asthma, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.6;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 16.2;NK-cells: 116.8;T-cells: 29.2;Undifferentiated cells: 30.6" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 68.2;MAIT T-cell: 33.5;memory CD8 T-cell: 40.9;naive CD8 T-cell: 22.6;NK-cell: 90.5" "Group enriched" "Detected in many" 33 "NK-cells: 90.5;T-cells: 68.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Stomach - Fibroblasts, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA046586, HPA049668" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 17: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane, Cytosol" "HPA046586: , HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" PTGDR2 "CD294, CRTH2, DP2, GPR44" ENSG00000183134 "Prostaglandin D2 receptor 2" Q9Y5Y4 11 60850933-60855950 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.0;skeletal muscle: 7.1;stomach 1: 9.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.7;granulocytes: 3.3;Intestinal goblet cells: 2.3;Langerhans cells: 2.7;Microglial cells: 1.8;monocytes: 7.6;Muller glia cells: 2.3;Smooth muscle cells: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 178.8;eosinophil: 234.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 234.5" "Cancer enriched" "Detected in single" 6 "Leukemia: 3.4" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014259 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA014259: AB_1849304" "unprognostic (9.77e-2)" "unprognostic (1.35e-3)" "unprognostic (5.45e-3)" "unprognostic (1.69e-1)" "unprognostic (1.90e-1)" "unprognostic (1.85e-3)" "unprognostic (1.70e-1)" "unprognostic (2.30e-4)" "unprognostic (2.61e-1)" "unprognostic (7.92e-2)" "unprognostic (8.68e-3)" "unprognostic (1.52e-1)" "unprognostic (1.32e-2)" "unprognostic (1.52e-1)" "unprognostic (3.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.99e-2)" PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047816 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.2;endometrium 1: 90.7;kidney: 77.9;smooth muscle: 65.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 156.7;Langerhans cells: 93.2;Mesothelial cells: 50.2" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 62 "basophil: 40.2" "Lineage enriched" "Detected in single" 62 "granulocytes: 40.2" "Cancer enriched" "Detected in some" 6 "Bone cancer: 47.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Dendritic cells - Antigen presentation" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.8;pancreas: 52.5" "Cell type enhanced" "Detected in many" "Langerhans cells: 144.6;monocytes: 379.9;NK-cells: 165.9;T-cells: 243.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.48e-4)" PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 81.3;urinary bladder: 75.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 90.7;Basal respiratory cells: 109.3;Cytotrophoblasts: 155.4;Extravillous trophoblasts: 333.3;Ionocytes: 92.4;Syncytiotrophoblasts: 300.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 29.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 29.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 15 "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.6;Cardiomyocytes: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 78.1;urinary bladder: 79.0" "Cell type enriched" "Detected in many" 4 "Mesothelial cells: 441.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.7" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 570.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Distal tubular cells: 49.2;Extravillous trophoblasts: 72.7;Late spermatids: 31.5;Proximal tubular cells: 214.6;Sertoli cells: 57.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 4.8" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 9 "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 15.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 11.9;Excitatory neurons: 15.4;Proximal tubular cells: 14.6;Rod photoreceptor cells: 24.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 150.8;Endometrial stromal cells: 76.3;Late spermatids: 188.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 68.9" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" Receptor NA NA 12000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Early spermatids - Spermatogenesis" 6 "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.2;Late spermatids: 570.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Testis - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 25 Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 227.3;dendritic cells: 326.8;monocytes: 313.1;Plasma cells: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 27 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 97.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 71: Thymus - Adaptive immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 2 Nucleoplasm Cytosol "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "brain: 297.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 57.1;Inhibitory neurons: 49.7" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.6;Rhabdoid: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 8 "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: AB_2686487" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2873420-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Fibroblasts - ECM organization" 3 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 205.9;Endothelial cells: 225.5;Inhibitory neurons: 65.7;Lymphatic endothelial cells: 77.8;Microglial cells: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 286.2" "Cell type enhanced" "Detected in many" "B-cells: 499.8;Macrophages: 517.0;monocytes: 1920.1;NK-cells: 1334.0;T-cells: 1095.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 84.8;lymphoma: 127.0" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221, CAB080251" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 24000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, CAB080251: , HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10613002 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.5;parathyroid gland: 17.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 4422.9;Inhibitory neurons: 1105.1;Oligodendrocyte precursor cells: 1098.0;Oligodendrocytes: 2932.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" Receptor NA NA 20000000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase receptor type E" P23469 10 127907103-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.4" "Cell type enhanced" "Detected in many" "dendritic cells: 489.3;Langerhans cells: 392.3;Macrophages: 282.5;monocytes: 722.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 643.1;plasmacytoid DC: 478.1" "Group enriched" "Detected in all" 12 "dendritic cells: 478.1;granulocytes: 643.1;monocytes: 177.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Monocytes - Innate immune response" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 335.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 160000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 338.4;Excitatory neurons: 401.9;Inhibitory neurons: 655.6;Microglial cells: 736.3;Oligodendrocyte precursor cells: 863.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 76: Oligodendrocyte precursor - Unknown function" 3 "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 23.4;intestine: 66.7;stomach 1: 23.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 28.3;Paneth cells: 35.3;Proximal enterocytes: 106.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008708 Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 4 "Nuclear speckles, Cytosol" "Plasma membrane" "HPA008708: " "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980425-48170839 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Microglial cells: 180.7;monocytes: 104.5;Oligodendrocyte precursor cells: 225.0;Oligodendrocytes: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" Enzyme NA NA 670000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 8 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 861.9;Oligodendrocyte precursor cells: 293.8;Oligodendrocytes: 1189.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 18: Non-specific - Translation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 2 "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 132.3;Astrocytes: 178.4;Inhibitory neurons: 720.5;Microglial cells: 251.4;Oligodendrocyte precursor cells: 210.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 30: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 157.9;pituitary gland: 177.5" "Group enriched" "Detected in some" 5 "Bipolar cells: 55.0;Cone photoreceptor cells: 64.6;Excitatory neurons: 43.1;Horizontal cells: 102.0;Inhibitory neurons: 46.1;Pancreatic endocrine cells: 81.5;Rod photoreceptor cells: 28.8" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.9;thyroid cancer: 38.6" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" NA NA 38000 "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 6 "Endoplasmic reticulum" "HPA007152: AB_2667759, HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavorable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.1;pancreas: 95.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 424.6;Inhibitory neurons: 415.5;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 23.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 34.0" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 35: Neutrophils - Protein binding" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.4;intestine: 26.0;kidney: 35.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 187.1;Horizontal cells: 53.5;Inhibitory neurons: 220.1;Oligodendrocyte precursor cells: 118.9;Undifferentiated cells: 50.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.0;Gastric cancer: 5.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 6.9;urinary bladder: 3.9" "Cell type enhanced" "Detected in some" "Early spermatids: 13.9;Excitatory neurons: 10.8;Late spermatids: 4.2;Mesothelial cells: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.5" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Alveolar cells type 1, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053245 Uncertain Approved Cytosol No NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.5;endometrium 1: 5.4;intestine: 7.4" "Group enriched" "Detected in some" 7 "Excitatory neurons: 192.5;Inhibitory neurons: 153.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.2;ovarian cancer: 10.4" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 4 "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340812 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.1;Excitatory neurons: 74.2;Horizontal cells: 50.4;Inhibitory neurons: 100.0;Oligodendrocyte precursor cells: 67.4;Oligodendrocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 197 "plasmacytoid DC: 153.7" "Lineage enriched" "Detected in single" 197 "dendritic cells: 153.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" Receptor NA NA 150000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.2;fallopian tube: 10.5;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 15 "Excitatory neurons: 483.8;Inhibitory neurons: 667.6;Oligodendrocyte precursor cells: 392.9" "Group enriched" "Detected in many" 5 "breast cancer: 5.1;prostate cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 1.0;Sarcoma: 2.3" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavorable (7.92e-4)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 156.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2547.0" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 21.7;skin cancer: 27.8" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" Enzyme NA NA 3400000 "Cluster 33: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 3 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" PTTG1IP "C21orf1, C21orf3, PBF, PTTG1IP1" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Macrophages, Lung - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 10 Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.4;intermediate monocyte: 4.4;myeloid DC: 3.6;neutrophil: 1.4;non-classical monocyte: 5.1" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 1.4;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" Receptor NA NA 720000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 52 "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" PVRIG "C7orf15, CD112R, MGC2463" ENSG00000213413 "PVR related immunoglobulin domain containing" Q6DKI7 7 100218241-100221490 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 46.6" "Cell type enhanced" "Detected in some" "B-cells: 3.4;Erythroid cells: 1.1;NK-cells: 3.1;Plasma cells: 1.3;T-cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 33 "gdT-cell: 297.4;MAIT T-cell: 352.7;memory B-cell: 174.9;memory CD4 T-cell: 193.5;memory CD8 T-cell: 293.8;naive B-cell: 155.3;naive CD4 T-cell: 213.7;naive CD8 T-cell: 212.0;NK-cell: 335.0;T-reg: 171.9" "Group enriched" "Detected in all" 39 "B-cells: 174.9;NK-cells: 335.0;T-cells: 352.7" "Group enriched" "Detected in some" 9 "Leukemia: 13.5;lymphoma: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047497 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" 1 "HPA047497: AB_2680069" "unprognostic (1.63e-2)" "unprognostic (1.28e-2)" "unprognostic (2.21e-3)" "unprognostic (5.13e-2)" "unprognostic (9.89e-2)" "unprognostic (1.53e-3)" "unprognostic (1.35e-3)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.81e-1)" "unprognostic (5.58e-2)" "unprognostic (5.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.17e-1)" "unprognostic (2.43e-2)" "unprognostic (4.12e-1)" "unprognostic (2.71e-3)" PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 74.7;Endometrial stromal cells: 98.6;Endothelial cells: 65.3;Fibroblasts: 54.4;Oligodendrocyte precursor cells: 52.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 51.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 181.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA012375 Approved "Secreted to extracellular matrix" Enzyme NA NA 9100000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" Peroxisomes "Nucleoli fibrillar center" "HPA050077: AB_2681006" "unprognostic (3.41e-2)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (5.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-1)" "prognostic favorable (3.88e-4)" "unprognostic (3.53e-1)" "unprognostic (4.47e-2)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.03e-10)" "unprognostic (3.84e-2)" "unprognostic (2.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.20e-1)" QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 569.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 58000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 36: Late spermatids - Unknown function" 53 Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" QRFPR GPR103 ENSG00000186867 "Pyroglutamylated RFamide peptide receptor" Q96P65 4 121328642-121381059 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;heart muscle: 1.4;kidney: 1.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.2;Early spermatids: 2.4;Endothelial cells: 2.1;Excitatory neurons: 5.6;Inhibitory neurons: 10.5;Microglial cells: 2.7" "Cancer enriched" "Detected in some" 6 "renal cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Bone cancer: 3.8;Kidney cancer: 4.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA050236 Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA050236: " "unprognostic (1.24e-2)" "unprognostic (2.30e-1)" "unprognostic (1.93e-2)" "unprognostic (3.21e-1)" "unprognostic (2.77e-1)" "unprognostic (3.21e-4)" "unprognostic (2.71e-1)" "unprognostic (5.77e-3)" "unprognostic (5.37e-2)" "unprognostic (6.33e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.09e-4)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Extravillous trophoblasts: 1872.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Enzyme NA NA 2600000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" QSOX2 "DKFZp762A2013, QSCN6L1, SOXN" ENSG00000165661 "Quiescin sulfhydryl oxidase 2" Q6ZRP7 9 136206333-136245812 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012716, HPA017280" Uncertain Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 9600000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: B-cells - B-cell function" "Golgi apparatus" Nucleoplasm "HPA012716: AB_2173315, HPA017280: AB_2669565" "unprognostic (7.29e-2)" "unprognostic (7.35e-3)" "unprognostic (6.23e-2)" "unprognostic (5.28e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-3)" "unprognostic (1.10e-3)" "unprognostic (4.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.06e-3)" "unprognostic (5.96e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (9.64e-6)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.10e-2)" RAB3GAP2 "DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69" ENSG00000118873 "RAB3 GTPase activating non-catalytic protein subunit 2" Q9H2M9 1 220148293-220272529 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026273, HPA027299" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA026273: AB_1856007, HPA027299: AB_1856008" "prognostic unfavorable (3.05e-4)" "unprognostic (2.80e-3)" "unprognostic (1.76e-2)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (7.00e-2)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (2.13e-1)" "unprognostic (7.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" RAB5IF "C20orf24, PNAS-11, RCAF1, RIP5" ENSG00000101084 "RAB5 interacting factor" Q9BUV8 20 36605779-36612557 "Disease related genes, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 209.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057387, HPA076106" Uncertain Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA057387: AB_2683425, HPA076106: " "unprognostic (2.14e-1)" "unprognostic (4.75e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-3)" "unprognostic (3.88e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.56e-6)" "unprognostic (4.47e-3)" "unprognostic (3.89e-1)" "unprognostic (2.90e-1)" "unprognostic (2.37e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.98e-2)" RABAC1 "PRA1, PRAF1, YIP3" ENSG00000105404 "Rab acceptor 1" Q9UI14 19 41956681-41959321 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019320, HPA029171" Supported NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" 48 "CAB019320: , HPA029171: AB_10602121" "unprognostic (7.70e-2)" "unprognostic (5.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.93e-1)" "unprognostic (3.41e-2)" "unprognostic (1.19e-2)" "unprognostic (3.32e-3)" "unprognostic (9.69e-2)" "unprognostic (1.76e-1)" "unprognostic (8.92e-2)" "unprognostic (2.31e-1)" "unprognostic (6.97e-2)" "unprognostic (7.45e-2)" RABGAP1 "GAPCenA, TBC1D11" ENSG00000011454 "RAB GTPase activating protein 1" Q9Y3P9 9 122940833-123104866 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 173.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064860, HPA072273" Enhanced Enhanced Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 32: Smooth muscle cells - Muscle contraction" 3 Cytosol "HPA064860: AB_2685372, HPA072273: AB_2686504" "prognostic unfavorable (8.09e-4)" "unprognostic (3.45e-1)" "unprognostic (3.85e-3)" "unprognostic (3.90e-1)" "unprognostic (4.16e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (3.75e-2)" "unprognostic (5.19e-2)" "unprognostic (3.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.06e-6)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (8.72e-2)" "unprognostic (3.05e-2)" RABGAP1L "FLJ38519, HHL, KIAA0471, TBC1D18" ENSG00000152061 "RAB GTPase activating protein 1 like" "B7ZAP0, Q5R372" 1 174159410-174995308 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 117.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 362.9;Excitatory neurons: 532.6;Inhibitory neurons: 425.7;Microglial cells: 255.0;Oligodendrocyte precursor cells: 340.1;Oligodendrocytes: 319.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 94.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054695 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 5: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA054695: AB_2682577" "unprognostic (2.57e-2)" "unprognostic (7.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.89e-3)" "unprognostic (1.54e-2)" "unprognostic (6.96e-3)" "unprognostic (8.55e-2)" "prognostic favorable (1.16e-4)" "unprognostic (2.66e-2)" "unprognostic (3.51e-2)" "unprognostic (2.66e-2)" "unprognostic (1.98e-1)" "unprognostic (9.14e-3)" "unprognostic (6.69e-2)" "unprognostic (2.14e-1)" "unprognostic (5.03e-2)" "unprognostic (2.46e-1)" RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Astrocytes: 143.1;Microglial cells: 251.4;Oligodendrocyte precursor cells: 147.6;Oligodendrocytes: 349.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Oligodendrocyte precursor - Unknown function" 7 "Nuclear bodies" Nucleoplasm "CAB016191: AB_2238209, HPA051869: AB_2681644" "unprognostic (9.10e-3)" "unprognostic (5.45e-2)" "unprognostic (4.92e-1)" "unprognostic (6.65e-2)" "unprognostic (2.38e-2)" "unprognostic (4.85e-2)" "unprognostic (6.42e-3)" "unprognostic (2.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (6.80e-3)" "unprognostic (1.47e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.49e-2)" "unprognostic (6.79e-2)" "unprognostic (8.13e-3)" RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883179-149898113 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 14.8;esophagus: 41.0;vagina: 19.9" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 92.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "cervical cancer: 23.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (other), Testis - Late spermatids" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.1;esophagus: 14.6" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 40.8;Mesothelial cells: 51.1;Suprabasal keratinocytes: 40.0" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 23.7" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 56.4;vagina: 16.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 9.5;Basal respiratory cells: 5.2;Collecting duct cells: 11.7;Squamous epithelial cells: 8.1;Suprabasal keratinocytes: 33.9" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 14.0;Gallbladder cancer: 20.6" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic subunit alpha 1" Q6GYQ0 14 35538352-35809304 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 208.0;Inhibitory neurons: 224.1;Oligodendrocyte precursor cells: 224.5;Oligodendrocytes: 384.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved Mitochondria,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol Mitochondria "HPA000851: AB_1078945" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (8.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-2)" "unprognostic (7.65e-2)" "unprognostic (1.17e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-2)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "prognostic favorable (9.76e-5)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 201.3;Microglial cells: 138.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Plasma membrane, Cytosol" "HPA042707: AB_2678124, HPA043622: AB_2678585" "unprognostic (7.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (1.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.34e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-2)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "prognostic favorable (3.77e-5)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (5.33e-2)" RAMP1 ENSG00000132329 "Receptor activity modifying protein 1" O60894 2 237858893-237912106 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 682.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 207.0;Endometrial stromal cells: 600.5;Prostatic glandular cells: 186.9;Skeletal myocytes: 285.9;Smooth muscle cells: 208.5" "Cancer enhanced" "Detected in all" "prostate cancer: 152.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "NK-cell: 70.4" "Lineage enriched" "Detected in many" 18 "NK-cells: 70.4" "Cancer enhanced" "Detected in many" "prostate cancer: 147.8" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057814 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 5 "Nucleoplasm, Nuclear membrane" "HPA057814: AB_2683536" "unprognostic (1.13e-2)" "unprognostic (5.96e-2)" "unprognostic (3.03e-3)" "unprognostic (3.69e-1)" "unprognostic (4.29e-1)" "unprognostic (1.75e-1)" "prognostic favorable (7.61e-4)" "unprognostic (2.54e-1)" "unprognostic (3.49e-1)" "unprognostic (5.45e-3)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (2.46e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (2.08e-3)" RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1017.0;Endothelial cells: 571.8;Lymphatic endothelial cells: 952.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.4" "Liver - Vascular Endothelial cells, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 3 Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 313.9;Endothelial cells: 285.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 12.3;breast cancer: 4.4" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 175.0;white matter: 60.1" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 140.3;Excitatory neurons: 96.9;Inhibitory neurons: 145.8;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 81.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 78: Testis - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: AB_10599825, HPA029569: AB_10601571" "unprognostic (4.63e-2)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (8.28e-2)" "unprognostic (1.75e-3)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.64e-2)" "unprognostic (2.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (2.56e-3)" RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 40.5" "Cell type enhanced" "Detected in many" "granulocytes: 220.6;Langerhans cells: 321.3;Macrophages: 187.0;monocytes: 520.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.7;plasmacytoid DC: 27.9" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 27.9;monocytes: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm Vesicles "HPA044574: AB_10794292" "unprognostic (3.24e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "prognostic favorable (1.49e-5)" "unprognostic (4.42e-2)" "unprognostic (6.31e-2)" "unprognostic (4.43e-1)" "unprognostic (4.85e-2)" "unprognostic (1.13e-2)" "unprognostic (3.88e-2)" "prognostic favorable (4.21e-6)" "unprognostic (4.19e-3)" "unprognostic (1.44e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 21.8;Inhibitory neurons: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 40: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 52: Non-specific - Cell proliferation" 6 Nucleoplasm "HPA054962: AB_2682652, HPA056525: AB_2683165" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-2)" "unprognostic (3.70e-3)" "unprognostic (2.13e-1)" "unprognostic (1.51e-1)" "unprognostic (6.25e-5)" "unprognostic (6.91e-2)" "unprognostic (7.19e-3)" "unprognostic (1.20e-1)" "unprognostic (4.49e-3)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (3.15e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 1 "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.4;Fibroblasts: 110.5;Leydig cells: 38.1;Ovarian stromal cells: 45.2;Pancreatic endocrine cells: 59.4;Peritubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 2.6;NK-cells: 1.8;T-cells: 6.9" "Cancer enhanced" "Detected in all" "Bone cancer: 127.6;Sarcoma: 142.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Transport No No 1600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 6 "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 171.1;Ionocytes: 210.2;Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" RDH16 "RODH-4, SDR9C8" ENSG00000139547 "Retinol dehydrogenase 16" O75452 12 56951431-56959374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "liver: 768.9" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 339.9" "Cancer enriched" "Detected in many" 20 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038518 Enhanced NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" "HPA038518: AB_10672713" "unprognostic (5.42e-3)" "unprognostic (4.20e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-2)" "prognostic favorable (2.16e-5)" "unprognostic (8.83e-3)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (6.85e-2)" "unprognostic (6.10e-1)" "unprognostic (7.99e-12)" "unprognostic (2.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" RDM1 "MGC33977, RAD52B" ENSG00000278023 "RAD52 motif containing 1" Q8NG50 17 35918066-35930773 "Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 11.5" "Cell type enhanced" "Detected in some" "Early spermatids: 39.1;Late spermatids: 94.5;Spermatocytes: 23.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 2.6" "Lineage enhanced" "Detected in single" "T-cells: 2.6" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA024794, HPA067546" Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Spermatocytes - Spermatogenesis" 4 Nucleoli Cytosol "HPA024794: AB_1856039, HPA067546: AB_2732769" "unprognostic (9.36e-2)" "unprognostic (2.40e-2)" "unprognostic (8.00e-2)" "unprognostic (4.57e-3)" "unprognostic (1.91e-2)" "unprognostic (1.26e-1)" "unprognostic (2.06e-4)" "unprognostic (5.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.71e-2)" "unprognostic (2.58e-2)" "unprognostic (3.24e-2)" "unprognostic (1.06e-8)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "unprognostic (7.00e-3)" "unprognostic (1.53e-1)" RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.1;Inhibitory neurons: 68.3;Oligodendrocyte precursor cells: 75.5;Oligodendrocytes: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 91.4;Oligodendrocyte precursor cells: 36.8;Sertoli cells: 95.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" 7 "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.9;choroid plexus: 100.8;retina: 58.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.0;Cone photoreceptor cells: 152.9;Excitatory neurons: 49.4;Horizontal cells: 61.1;Inhibitory neurons: 44.2;Rod photoreceptor cells: 59.1" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.1" "Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 21 "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 86.8;skin 1: 88.2" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 93.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 92 "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Mixed function" 6 "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 211.2;liver: 388.3;testis: 276.0" "Group enriched" "Detected in many" 5 "Late spermatids: 3055.8;Proximal enterocytes: 905.4" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Late spermatids" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 11 "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 126.8;Inhibitory neurons: 93.1;Microglial cells: 82.3;Oligodendrocyte precursor cells: 104.7;Oligodendrocytes: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 51: Oligodendrocytes - Unknown function" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.7;dendritic cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 58.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 32: Non-specific - Cell proliferation" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" RELL2 "C5orf16, FLJ90583" ENSG00000164620 "RELT like 2" Q8NC24 5 141636950-141641064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.0;parathyroid gland: 15.6;pituitary gland: 15.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.4;Excitatory neurons: 27.5;Horizontal cells: 47.2;Inhibitory neurons: 27.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077928 Uncertain Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 16 Vesicles "HPA077928: " "unprognostic (3.27e-2)" "unprognostic (8.46e-2)" "unprognostic (2.12e-1)" "unprognostic (4.95e-3)" "unprognostic (1.91e-3)" "unprognostic (7.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.69e-2)" "unprognostic (2.12e-2)" "unprognostic (6.76e-4)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-3)" "unprognostic (4.31e-2)" "unprognostic (6.58e-2)" RELT "FLJ14993, TNFRSF19L" ENSG00000054967 "RELT TNF receptor" Q969Z4 11 73376399-73397474 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 152.9" "Cell type enhanced" "Detected in many" "dendritic cells: 53.0;Langerhans cells: 47.4;Macrophages: 44.7;monocytes: 110.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062824, HPA071518" Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm "HPA062824: AB_2684875, HPA071518: AB_2686408" "unprognostic (3.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.80e-3)" "unprognostic (9.92e-3)" "unprognostic (1.67e-3)" "unprognostic (1.17e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-1)" "unprognostic (8.42e-2)" "unprognostic (4.13e-2)" "prognostic unfavorable (4.07e-11)" "unprognostic (1.64e-1)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (1.69e-1)" RER1 ENSG00000157916 "Retention in endoplasmic reticulum sorting receptor 1" O15258 1 2391775-2405442 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 503.1;Syncytiotrophoblasts: 520.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037240, HPA051400" Supported Supported "Golgi apparatus" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus" "CAB037240: AB_2179604, HPA051400: AB_2681469" "unprognostic (2.90e-2)" "unprognostic (3.35e-2)" "unprognostic (3.17e-2)" "unprognostic (2.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.23e-8)" "unprognostic (1.01e-1)" "unprognostic (5.41e-2)" "unprognostic (1.06e-1)" "unprognostic (3.27e-2)" RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.1;brain: 15.1;parathyroid gland: 19.3" "Cell type enhanced" "Detected in some" "dendritic cells: 47.2;Horizontal cells: 28.3;Lymphatic endothelial cells: 10.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 97.7;thyroid cancer: 31.6" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 86.5;spinal cord: 33.3" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" 5 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617101 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 97.1;skeletal muscle: 136.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.8;Early spermatids: 483.0;Glandular and luminal cells: 239.2;Late spermatids: 716.6;Oligodendrocytes: 272.7;Skeletal myocytes: 250.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "granulocytes: 9.4;T-cells: 8.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" RETREG2 "C2orf17, FAM134A, MAG-2, MGC3035" ENSG00000144567 "Reticulophagy regulator family member 2" Q8NC44 2 219176225-219185475 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 159.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011170, HPA011844, HPA075910" Approved Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Cytosol "Golgi apparatus" "HPA011170: AB_1845713, HPA011844: AB_2668544, HPA075910: " "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.95e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (1.49e-4)" "unprognostic (8.74e-2)" "unprognostic (9.61e-2)" "unprognostic (1.34e-2)" "unprognostic (4.37e-2)" "unprognostic (2.36e-1)" "unprognostic (4.29e-3)" "unprognostic (4.45e-2)" "unprognostic (4.47e-2)" "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" RETREG3 "DKFZp686B1036, FAM134C, FLJ33806" ENSG00000141699 "Reticulophagy regulator family member 3" Q86VR2 17 42579513-42610623 "Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 89.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016492 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 91 "Nucleoplasm, Nuclear membrane" Cytosol "HPA016492: AB_1853027" "unprognostic (6.79e-2)" "unprognostic (1.29e-2)" "unprognostic (2.78e-1)" "prognostic favorable (1.61e-4)" "unprognostic (5.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.53e-2)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" "unprognostic (2.58e-2)" "unprognostic (1.00e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.24e-1)" "unprognostic (5.68e-1)" "unprognostic (9.64e-3)" "unprognostic (5.43e-2)" RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.4;Proximal enterocytes: 241.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007961 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA007961: AB_1079802" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" RFT1 CDG1N ENSG00000163933 "RFT1 homolog" Q96AA3 3 53088483-53130453 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060327, HPA069022" Approved Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 9 Vesicles "HPA060327: AB_2684253, HPA069022: AB_2732126" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (5.16e-3)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.48e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (3.54e-2)" RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 61.0;Undifferentiated cells: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 134.8" "Cell type enriched" "Detected in some" 39 "Muller glia cells: 1357.4" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 25.5;olfactory bulb: 55.9;thalamus: 29.6" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 1 Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 12.2;retina: 16.8;skeletal muscle: 8.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 31.3;Cone photoreceptor cells: 91.8;Rod photoreceptor cells: 66.8" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "choroid plexus: 62.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" RHAG "CD241, RH50A, SLC42A1" ENSG00000112077 "Rh associated glycoprotein" Q02094 6 49605175-49636839 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 117.8" "Cell type enriched" "Detected in some" 16 "Erythroid cells: 366.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 107.7" "Liver - Erythroid cells, Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA046051, HPA055331" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 4 "Endoplasmic reticulum" "HPA046051: , HPA055331: AB_2682785" "unprognostic (8.16e-2)" "unprognostic (6.86e-2)" "unprognostic (1.25e-3)" "unprognostic (1.65e-1)" RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 63.5;Microglial cells: 54.6;Oligodendrocyte precursor cells: 52.4;Oligodendrocytes: 101.4;Plasma cells: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 73: B-cells - B-cell function" 11 "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" RHBDD2 "NPD007, RHBDL7" ENSG00000005486 "Rhomboid domain containing 2" Q6NTF9 7 75842602-75888926 "Enzymes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 345.4;choroid plexus: 366.9" "Cell type enhanced" "Detected in all" "Early spermatids: 175.3;Late spermatids: 295.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 400.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045074, HPA051960" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 2 "Golgi apparatus" "HPA045074: AB_10965705, HPA051960: AB_2681673" "unprognostic (2.75e-1)" "unprognostic (3.89e-2)" "prognostic unfavorable (3.31e-5)" "unprognostic (9.79e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (2.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.87e-2)" "prognostic favorable (8.68e-6)" "unprognostic (3.73e-1)" "unprognostic (6.53e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-1)" RHBDD3 "C22orf3, PTAG" ENSG00000100263 "Rhomboid domain containing 3" Q9Y3P4 22 29259872-29268209 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043979 Approved Approved Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Testis - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "HPA043979: AB_10960539" "unprognostic (9.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.22e-1)" "prognostic favorable (2.67e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.13e-3)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.42e-3)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.11e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (3.42e-3)" RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Schwann cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 60.2;Ionocytes: 55.6;Kupffer cells: 69.2;Langerhans cells: 55.5;Macrophages: 53.7;monocytes: 79.4;NK-cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: B-cells - B-cell function" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675671-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 36.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.4;Excitatory neurons: 29.1;Horizontal cells: 33.4;Inhibitory neurons: 25.9;Proximal enterocytes: 16.6;Rod photoreceptor cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 8 Nucleoplasm "HPA030359: AB_2673445, HPA030360: AB_2673446, HPA046593: AB_2679711" "prognostic favorable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 23.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 73.3;Club cells: 47.1;Distal enterocytes: 55.3;Ionocytes: 51.2;Oligodendrocytes: 50.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32265832-32324659 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7;heart muscle: 13.3;retina: 25.3" "Cell type enhanced" "Detected in some" "Astrocytes: 39.6;Cone photoreceptor cells: 18.7;Excitatory neurons: 45.3;Horizontal cells: 37.8;Oligodendrocyte precursor cells: 71.2;Rod photoreceptor cells: 35.0" "Cancer enriched" "Detected in some" 4 "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA059607: AB_2684081" "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;kidney: 9.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 17.5;Distal tubular cells: 24.6;Granulosa cells: 27.5;Hepatocytes: 10.8;Late spermatids: 15.3;Ovarian stromal cells: 13.8" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 15 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes, Pancreas - Exocrine glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" RHCE "CD240CE, RH" ENSG00000188672 "Rh blood group CcEe antigens" P18577 1 25362249-25430192 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 47.8" "Cell type enriched" "Detected in some" 33 "Erythroid cells: 254.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Leukemia: 5.4" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (1.37e-1)" "unprognostic (3.53e-1)" "unprognostic (2.38e-1)" "unprognostic (6.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.12e-2)" "unprognostic (3.81e-2)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "unprognostic (4.61e-2)" "unprognostic (5.77e-5)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" "unprognostic (7.15e-3)" "unprognostic (1.63e-1)" RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3909.7;vagina: 1676.0" "Group enriched" "Detected in many" 5 "Squamous epithelial cells: 1891.1;Suprabasal keratinocytes: 4529.9" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 21.0;head and neck cancer: 25.3" "Kidney - Intercalated cells, Prostate - Urothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in many" "HPA041874, HPA043317" Enhanced NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 13 "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" RHD "CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI" ENSG00000187010 "Rh blood group D antigen" Q02161 1 25272393-25330445 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 15.5" "Cell type enriched" "Detected in some" 15 "Erythroid cells: 104.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cancer enriched" "Detected in single" 4 "Leukemia: 3.0" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (4.75e-3)" "unprognostic (7.70e-2)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.09e-2)" "unprognostic (4.84e-2)" "unprognostic (1.11e-2)" "unprognostic (5.25e-2)" "unprognostic (1.11e-2)" "unprognostic (1.91e-1)" "unprognostic (1.27e-2)" "unprognostic (1.89e-1)" "unprognostic (4.96e-3)" "unprognostic (1.93e-1)" "unprognostic (8.09e-2)" "unprognostic (5.53e-2)" "unprognostic (4.92e-3)" RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.5" "Cell type enriched" "Detected in some" 8 "granulocytes: 616.7" "Group enriched" "Detected in many" 5 "endometrial cancer: 42.8;ovarian cancer: 41.1;renal cancer: 27.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1318.2" "Lineage enriched" "Detected in single" 1550 "granulocytes: 1318.2" "Cancer enhanced" "Detected in many" "Leukemia: 58.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells" "Low region specificity" "Detected in all" HPA037859 Supported "Plasma membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 6 "Plasma membrane" "HPA037859: AB_10697084" "unprognostic (9.26e-3)" "unprognostic (1.91e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-2)" "unprognostic (2.06e-2)" "unprognostic (5.27e-3)" "unprognostic (9.55e-2)" "unprognostic (3.04e-3)" "unprognostic (2.36e-1)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (7.20e-3)" "unprognostic (1.89e-2)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (3.77e-2)" "unprognostic (2.80e-3)" RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528639-129535344 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8215 "retina: 3936.5" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 3749.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "cerebral cortex: 1.0;hippocampal formation: 1.5" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 66: Photoreceptor cells - Visual perception" 2 "CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: AB_2668844" "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-11)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-1)" RHOT1 "ARHT1, FLJ11040, MIRO-1, MIRO1" ENSG00000126858 "Ras homolog family member T1" Q8IXI2 17 32142454-32253374 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010687, CAB068223, CAB068224" Supported NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 10: Muller glia cells - Visual perception" 4 "CAB068223: AB_2665691, CAB068224: AB_2665692, HPA010687: AB_1079813" "unprognostic (3.28e-2)" "unprognostic (4.02e-3)" "unprognostic (6.85e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.49e-2)" "unprognostic (1.59e-3)" "unprognostic (1.59e-2)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (5.05e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.90e-1)" "unprognostic (4.08e-2)" RHOT2 "ARHT2, C16orf39, MIRO-2, MIRO2" ENSG00000140983 "Ras homolog family member T2" Q8IXI1 16 668100-674174 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 217.5;Rod photoreceptor cells: 294.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012624, HPA012895" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 66: Photoreceptor cells - Visual perception" 4 Mitochondria "HPA012624: AB_1856272, HPA012895: AB_1856271" "unprognostic (1.59e-1)" "unprognostic (8.24e-2)" "unprognostic (1.03e-1)" "unprognostic (4.50e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.01e-4)" "unprognostic (4.68e-3)" "unprognostic (4.66e-2)" "unprognostic (3.41e-2)" "unprognostic (7.55e-2)" "unprognostic (7.87e-3)" "unprognostic (3.25e-1)" "prognostic favorable (5.43e-4)" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (1.24e-1)" "unprognostic (2.17e-2)" RIC1 "bA207C16.1, KIAA1432" ENSG00000107036 "RIC1 homolog, RAB6A GEF complex partner 1" Q4ADV7 9 5629025-5776557 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 81.7;Inhibitory neurons: 76.3;Microglial cells: 93.9;Oligodendrocyte precursor cells: 65.6;Oligodendrocytes: 65.7;Plasma cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051578 Supported NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: B-cells - B-cell function" "HPA051578: AB_2681541" "unprognostic (1.78e-1)" "unprognostic (4.08e-2)" "unprognostic (3.13e-2)" "unprognostic (2.47e-2)" "unprognostic (4.51e-2)" "unprognostic (8.87e-2)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" "unprognostic (3.87e-2)" "unprognostic (7.16e-2)" "unprognostic (8.96e-2)" "unprognostic (3.92e-2)" "unprognostic (3.74e-1)" "unprognostic (3.50e-2)" "unprognostic (4.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.77e-2)" RIC3 "AYST720, FLJ11608, PRO1385" ENSG00000166405 "RIC3 acetylcholine receptor chaperone" Q7Z5B4 11 8106056-8169055 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 162.8;Horizontal cells: 130.9;Rod photoreceptor cells: 213.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 12.8;granulocytes: 3.7;T-cells: 6.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.6;prostate cancer: 4.0;testis cancer: 4.0" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065016 Approved "Intracellular and membrane" Other NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "HPA065016: AB_2685404" "unprognostic (2.51e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-1)" "unprognostic (6.98e-4)" "unprognostic (3.22e-2)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.48e-2)" "unprognostic (4.45e-4)" "unprognostic (1.28e-1)" "unprognostic (2.23e-9)" "unprognostic (4.37e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "unprognostic (2.52e-2)" RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 41.1" "Group enriched" "Detected in many" 6 "Early spermatids: 278.4;Late spermatids: 181.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Late spermatids - Unknown function" 11 "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: AB_2674292, HPA034706: AB_10696362" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.06e-2)" "prognostic favorable (2.63e-4)" "unprognostic (7.85e-2)" "unprognostic (9.96e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-2)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "unprognostic (4.34e-3)" "unprognostic (3.34e-1)" RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 23 Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" RMND1 "bA351K16.3, C6orf96, FLJ20627, RMD1" ENSG00000155906 "Required for meiotic nuclear division 1 homolog" Q9NWS8 6 151398898-151452158 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031397, HPA031398, HPA031399" Approved Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 1 Mitochondria "HPA031397: AB_2673861, HPA031398: AB_2673862, HPA031399: AB_10601156" "unprognostic (1.12e-1)" "unprognostic (4.45e-2)" "unprognostic (9.70e-3)" "unprognostic (6.67e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.50e-3)" "unprognostic (6.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.73e-1)" "unprognostic (2.03e-1)" "unprognostic (3.57e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (9.74e-2)" "unprognostic (1.04e-1)" RNASEK MGC71993 ENSG00000219200 "Ribonuclease K" Q6P5S7 17 7012417-7014532 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hydrogen ion transport, Ion transport, Transport" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 234.7;Macrophages: 125.2;Plasma cells: 159.5;Squamous epithelial cells: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044708 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 22 "HPA044708: AB_10962051" "unprognostic (7.59e-2)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "unprognostic (5.92e-2)" "unprognostic (9.73e-3)" "unprognostic (4.82e-2)" "unprognostic (3.65e-1)" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (6.50e-3)" "prognostic favorable (1.92e-4)" "unprognostic (2.93e-3)" "unprognostic (1.72e-3)" "unprognostic (1.81e-1)" "unprognostic (1.77e-2)" "unprognostic (1.14e-1)" "unprognostic (2.33e-3)" RNASEK-C17orf49 ENSG00000161939 "RNASEK-C17orf49 readthrough" 17 7012635-7017520 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Ductal cells: 6.4;Exocrine glandular cells: 3.8;Pancreatic endocrine cells: 8.5;Proximal enterocytes: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA022961, HPA024457" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" Nucleoplasm Cytosol "HPA022961: AB_1845592, HPA024457: AB_1845593" "unprognostic (4.08e-2)" "unprognostic (3.30e-1)" "unprognostic (1.58e-1)" "unprognostic (9.37e-5)" "unprognostic (4.19e-1)" "unprognostic (1.71e-1)" "unprognostic (7.91e-2)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (2.87e-1)" "unprognostic (3.77e-3)" "unprognostic (8.26e-3)" "unprognostic (8.58e-3)" "unprognostic (3.00e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.78e-1)" RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603398-86623866 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA057922: AB_2683555" "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favorable (6.77e-5)" RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 106.4" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Bipolar cells: 6.9;Excitatory neurons: 18.9;Inhibitory neurons: 11.1;Muller glia cells: 6.5;Oligodendrocyte precursor cells: 12.7" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 15.4" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 18 "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" RNF122 FLJ12526 ENSG00000133874 "Ring finger protein 122" Q9H9V4 8 33547754-33567128 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.9;dendritic cells: 16.3;Glandular and luminal cells: 17.7;monocytes: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 39.2" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003888 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "HPA003888: AB_1079822" "unprognostic (2.36e-2)" "unprognostic (3.13e-1)" "unprognostic (2.09e-2)" "unprognostic (9.19e-3)" "unprognostic (2.46e-1)" "unprognostic (8.78e-3)" "unprognostic (1.71e-2)" "unprognostic (5.46e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (6.95e-2)" "prognostic favorable (5.37e-4)" "prognostic unfavorable (4.50e-7)" "unprognostic (4.45e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (7.15e-2)" RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.3;liver: 120.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.0;Distal enterocytes: 41.1;Gastric mucus-secreting cells: 47.2;Hepatocytes: 62.6;Intestinal goblet cells: 40.9;Proximal enterocytes: 73.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 341.7;Oligodendrocytes: 550.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 464.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" 1 "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 297.9;Hofbauer cells: 335.2;Kupffer cells: 316.9;Oligodendrocytes: 478.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 262.7;classical monocyte: 513.7;eosinophil: 331.9;intermediate monocyte: 355.0;myeloid DC: 407.7;neutrophil: 893.5;non-classical monocyte: 330.1;plasmacytoid DC: 317.6" "Group enriched" "Detected in all" 11 "dendritic cells: 407.7;granulocytes: 893.5;monocytes: 513.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474880-124488618 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 92.0" "Group enriched" "Detected in all" 9 "Early spermatids: 684.3;Late spermatids: 1119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" 2 "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 55.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 170.7;Inhibitory neurons: 97.6;Oligodendrocyte precursor cells: 182.5;Oligodendrocytes: 307.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 8 "granulocytes: 6.1;T-cells: 2.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.7;skin cancer: 30.3" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 65: Cerebellum - Nervous system development" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" 10 Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468870 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 54.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 326.7;Langerhans cells: 296.8;monocytes: 1645.6;Schwann cells: 263.9;Suprabasal keratinocytes: 714.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 72.3" "Group enriched" "Detected in many" 9 "dendritic cells: 18.4;granulocytes: 36.8;monocytes: 72.3" "Cancer enhanced" "Detected in many" "lymphoma: 28.9" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 3 Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: AB_2682391, HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 330.3;Langerhans cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Monocytes - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" RNF148 MGC35222 ENSG00000235631 "Ring finger protein 148" Q8N7C7 7 122701668-122702922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 47.9" "Cell type enriched" "Detected in some" 6 "Early spermatids: 523.2" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebellum: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045587 Approved Cytosol NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" Cytosol "HPA045587: AB_10963695" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (3.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.85e-1)" "unprognostic (3.23e-2)" "unprognostic (1.04e-2)" "unprognostic (9.81e-2)" "unprognostic (8.48e-2)" "unprognostic (2.14e-2)" "unprognostic (2.18e-1)" "unprognostic (2.37e-1)" "unprognostic (3.33e-2)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-2)" "unprognostic (1.09e-1)" RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 359.8;Kupffer cells: 292.2;monocytes: 802.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 621.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 621.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Neutrophils - Degranulation" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" RNF150 KIAA1214 ENSG00000170153 "Ring finger protein 150" Q9ULK6 4 140859807-141212877 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 98.4;Cone photoreceptor cells: 93.5;Excitatory neurons: 178.3;Inhibitory neurons: 166.7;Microglial cells: 109.1;Oligodendrocyte precursor cells: 267.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 26.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037987 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA037987: AB_10669512" "prognostic favorable (1.41e-4)" "unprognostic (1.95e-2)" "unprognostic (8.26e-3)" "unprognostic (2.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.38e-2)" "unprognostic (2.38e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (9.32e-2)" "unprognostic (3.10e-3)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (3.88e-3)" "unprognostic (9.68e-2)" "unprognostic (1.32e-3)" "unprognostic (2.41e-2)" RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 3 "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Retina - Visual perception" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Non-specific - Transcription" 1 "HPA050931: AB_2681279, HPA054621: AB_2682545" "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.1" "Group enriched" "Detected in some" 4 "Early spermatids: 92.6;Excitatory neurons: 88.3;Inhibitory neurons: 91.7;Oligodendrocyte precursor cells: 36.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bone cancer: 4.4;skin cancer: 3.9" "Colon - Colon enteroendocrine cells, Kidney - Macrophages, Liver - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" HPA035837 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165843-64372869 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 24.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.4;Inhibitory neurons: 145.2;Oligodendrocyte precursor cells: 152.3" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favorable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;brain: 16.2;retina: 8.5" "Cell type enriched" "Detected in some" 4 "Astrocytes: 80.8" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 43.2" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 47: Astrocytes - Unknown function" 4 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 15.8;kidney: 11.2" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 15.9;Ciliated cells: 10.5;Enteroendocrine cells: 9.2;Glandular and luminal cells: 17.1;Ionocytes: 31.7;Proximal tubular cells: 25.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.2" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057675 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Proximal tubular cells - Transmembrane transport" 30 "HPA057675: AB_2683499" "unprognostic (1.23e-2)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.95e-6)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.51e-4)" "unprognostic (5.50e-2)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (2.53e-3)" RNF186 FLJ20225 ENSG00000178828 "Ring finger protein 186" Q9NXI6 1 19814029-19815283 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 65.7;intestine: 127.3;pancreas: 42.2" "Group enriched" "Detected in some" 7 "Distal enterocytes: 71.0;Enteroendocrine cells: 120.2;Intestinal goblet cells: 43.0;Paneth cells: 137.3;Proximal tubular cells: 90.7;Undifferentiated cells: 83.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 18.5;renal cancer: 12.1;stomach cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.2;ovarian cancer: 1.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "HPA034547, HPA035558" Enhanced NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "HPA034547: AB_10670975, HPA035558: AB_2674678" "unprognostic (1.66e-2)" "unprognostic (2.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.93e-3)" "unprognostic (1.77e-3)" "unprognostic (3.23e-1)" "unprognostic (3.05e-1)" "unprognostic (3.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.76e-1)" "unprognostic (1.40e-1)" "unprognostic (8.60e-3)" RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 267.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favorable (3.28e-5)" RNF19B "FLJ90005, IBRDC3, NKLAM" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 76.7" "Cell type enhanced" "Detected in many" "monocytes: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 27 Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260852-80398794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Immunity, Lipid metabolism, Ubl conjugation pathway" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 328.2;Exocrine glandular cells: 292.9;NK-cells: 342.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" RNF215 ENSG00000099999 "Ring finger protein 215" Q9Y6U7 22 30368811-30421771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029427, HPA056498" Approved Approved Nucleoli,Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 33: Non-specific - DNA binding" Microtubules Nucleoli "HPA029427: AB_2732447, HPA056498: AB_2683154" "unprognostic (1.24e-2)" "unprognostic (3.20e-1)" "unprognostic (3.67e-4)" "unprognostic (8.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (1.97e-1)" "unprognostic (5.32e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (6.37e-10)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962437-125092633 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Early spermatids: 151.2;Oligodendrocytes: 95.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 55: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Early spermatids - Spermatogenesis" "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavorable (1.92e-4)" RNF222 ENSG00000189051 "Ring finger protein 222" A6NCQ9 17 8390702-8397827 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.4;skin 1: 6.7;vagina: 5.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;NK-cells: 1.0;Rod photoreceptor cells: 1.3;Suprabasal keratinocytes: 6.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048916 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA048916: AB_2680555" "unprognostic (2.49e-1)" "unprognostic (4.19e-2)" "unprognostic (2.32e-2)" "unprognostic (8.19e-4)" "unprognostic (2.81e-1)" "unprognostic (5.30e-2)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (9.55e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-3)" "unprognostic (5.82e-2)" "unprognostic (6.70e-2)" "unprognostic (5.98e-3)" "unprognostic (3.97e-2)" RNF24 G1L ENSG00000101236 "Ring finger protein 24" Q9Y225 20 3927309-4015558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 51.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.7;Inhibitory neurons: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 239.1" "Lineage enriched" "Detected in all" 10 "granulocytes: 239.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011900 Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 9: Endometrial stromal cells - Transcription" 1 "Golgi apparatus" "HPA011900: AB_10671089" "unprognostic (6.61e-2)" "unprognostic (6.56e-2)" "unprognostic (1.72e-1)" "unprognostic (1.17e-2)" "unprognostic (8.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.65e-1)" "unprognostic (5.87e-2)" "unprognostic (2.66e-2)" "unprognostic (5.19e-3)" "unprognostic (3.42e-1)" "prognostic unfavorable (2.67e-7)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 44.4;Extravillous trophoblasts: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 4 Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1" "Cell type enhanced" "Detected in many" "Astrocytes: 27.6;Distal enterocytes: 18.1;Intestinal goblet cells: 23.3;Undifferentiated cells: 32.9" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Region enhanced" "Detected in all" "cerebellum: 19.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 45.8;colorectal cancer: 71.5" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008079 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 5 "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 270.6;Proximal tubular cells: 321.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 44 "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" RNFT1 PTD016 ENSG00000189050 "Ring finger protein, transmembrane 1" Q5M7Z0 17 59952240-59964761 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.1" "Cell type enhanced" "Detected in all" "Early spermatids: 145.1;Late spermatids: 113.8;Spermatocytes: 215.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013739 Approved Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Testis - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoli "HPA013739: AB_1856382" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "prognostic favorable (6.57e-4)" "unprognostic (3.04e-2)" "unprognostic (6.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-2)" "prognostic favorable (7.48e-4)" "unprognostic (5.42e-2)" "unprognostic (3.45e-1)" "unprognostic (8.26e-3)" "unprognostic (9.44e-3)" "unprognostic (1.19e-3)" "unprognostic (1.44e-2)" "unprognostic (2.05e-1)" "prognostic favorable (2.57e-4)" "unprognostic (2.60e-1)" RNFT2 "FLJ14627, TMEM118" ENSG00000135119 "Ring finger protein, transmembrane 2" Q96EX2 12 116738178-116853631 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 10.9;choroid plexus: 4.9;pituitary gland: 5.0;retina: 4.8;testis: 3.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 17.0;Early spermatids: 29.7;Excitatory neurons: 21.9;Inhibitory neurons: 27.5;Late spermatids: 75.7;Oligodendrocyte precursor cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064161 Enhanced Approved Nucleoplasm,Cytosol No No "Cluster 34: B-cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA064161: AB_2685202" "unprognostic (1.56e-1)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (3.59e-1)" "unprognostic (3.98e-1)" "unprognostic (3.10e-2)" "unprognostic (8.14e-5)" "unprognostic (8.62e-2)" "unprognostic (6.28e-3)" "unprognostic (2.58e-1)" "unprognostic (9.25e-3)" "unprognostic (2.75e-1)" "unprognostic (7.61e-3)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.36e-3)" "unprognostic (4.01e-4)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 299.1;Inhibitory neurons: 1449.4;Oligodendrocyte precursor cells: 326.9;Oligodendrocytes: 446.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7;ovary: 13.5" "Group enriched" "Detected in many" 25 "Excitatory neurons: 3318.5;Inhibitory neurons: 4497.7" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Podocytes, Lung - Fibroblast_1, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 34.7;Lymphatic endothelial cells: 33.6;Mesothelial cells: 42.1;Muller glia cells: 42.8" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 6: Ovarian stromal cells - Transcription" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 171.6;Endothelial cells: 112.8;Lymphatic endothelial cells: 146.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "retina: 1150.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 642.5;Cone photoreceptor cells: 717.0;Muller glia cells: 405.0;Rod photoreceptor cells: 2757.9" "Cancer enriched" "Detected in all" 6 "glioma: 14.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028910, HPA073279" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 3 "Plasma membrane, Cytosol" "HPA028910: AB_2672824, HPA073279: " "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (4.05e-1)" "prognostic favorable (2.20e-4)" "unprognostic (2.20e-1)" "unprognostic (9.87e-2)" "unprognostic (7.65e-3)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.61e-1)" "unprognostic (4.65e-1)" "unprognostic (1.02e-1)" "unprognostic (7.24e-2)" ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "epididymis: 57.2;lung: 30.7" "Cell type enriched" "Detected in some" 8 "Alveolar cells type 2: 148.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enhanced" "Detected in some" "cerebral cortex: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.6;Bone cancer: 8.7;Brain cancer: 5.6" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Alveolar cells - Lung function" 1 Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" RPAP1 "DKFZP727M111, FLJ12732, KIAA1403, MGC858" ENSG00000103932 "RNA polymerase II associated protein 1" Q9BWH6 15 41517176-41544269 "Predicted intracellular proteins, Predicted membrane proteins" Transcription "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041739 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 2 Nucleoplasm Cytosol "HPA041739: AB_2677647" "unprognostic (8.83e-3)" "unprognostic (2.78e-3)" "unprognostic (1.63e-1)" "unprognostic (4.45e-2)" "unprognostic (1.97e-1)" "unprognostic (8.61e-2)" "unprognostic (1.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-2)" "unprognostic (7.02e-2)" "unprognostic (3.73e-2)" "unprognostic (3.26e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (9.32e-4)" "unprognostic (4.30e-3)" RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92299059-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" 4 "Nucleoli, Cytosol" "HPA046443: AB_2679669" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 102.7;Endothelial cells: 83.3;Lymphatic endothelial cells: 88.9;Rod photoreceptor cells: 79.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.8" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" RPL9 L9 ENSG00000163682 "Ribosomal protein L9" P32969 4 39452587-39458931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003372 Approved Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 180000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 28 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA003372: AB_1079843" "unprognostic (1.08e-3)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" "unprognostic (8.06e-3)" "unprognostic (5.59e-2)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (8.58e-2)" "unprognostic (6.68e-2)" "unprognostic (2.50e-2)" "unprognostic (7.85e-2)" "prognostic unfavorable (7.34e-4)" "unprognostic (1.34e-1)" "unprognostic (2.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-2)" RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 408.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 730000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 61: Plasma cells - Immunoglobulins & histones" 7 "Endoplasmic reticulum" Cytosol "CAB009748: AB_2182230, HPA026828: AB_10610418, HPA051520: AB_2681521" "unprognostic (4.83e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" "unprognostic (4.58e-3)" "unprognostic (2.87e-1)" "unprognostic (7.68e-2)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.74e-2)" RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 652.6;Oocytes: 844.0;Syncytiotrophoblasts: 655.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "CAB019277: , HPA008297: AB_1856457, HPA025922: AB_1856458" "unprognostic (9.59e-3)" "unprognostic (5.22e-2)" "unprognostic (1.66e-2)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.44e-10)" "unprognostic (2.83e-1)" "unprognostic (6.99e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.44e-4)" RPRML MGC43894 ENSG00000179673 "Reprimo like" Q8N4K4 17 46978156-46979253 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 26 "brain: 48.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 41.3;Excitatory neurons: 16.8;Suprabasal keratinocytes: 7.9" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 118.6" HPA062668 Uncertain NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA062668: AB_2684827" "unprognostic (7.79e-4)" "unprognostic (1.66e-2)" "unprognostic (8.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.31e-1)" "unprognostic (8.93e-4)" "unprognostic (2.78e-2)" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" RPS10 "MGC88819, S10" ENSG00000124614 "Ribosomal protein S10" P46783 6 34417454-34426069 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Undifferentiated cells: 3362.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047268, HPA048084" Approved Approved Cytosol NA NA 130000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 2 Cytosol "HPA047268: AB_2680007, HPA048084: AB_2680255" "unprognostic (1.92e-1)" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.78e-1)" "unprognostic (8.92e-3)" "unprognostic (3.79e-2)" "unprognostic (9.72e-3)" "unprognostic (1.93e-2)" "unprognostic (4.30e-3)" "unprognostic (2.04e-1)" "unprognostic (3.59e-1)" "unprognostic (3.82e-1)" "prognostic unfavorable (2.57e-6)" "unprognostic (4.98e-2)" "unprognostic (7.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.45e-1)" RPS15A S15A ENSG00000134419 "Ribosomal protein S15a" P62244 16 18781295-18790383 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047103 Supported NA NA 210000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 8 "HPA047103: AB_10959516" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.53e-2)" "unprognostic (6.75e-2)" "unprognostic (5.40e-2)" "unprognostic (2.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.19e-1)" "unprognostic (4.18e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.29e-7)" "unprognostic (1.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (6.32e-2)" RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 43.7;Excitatory neurons: 67.6;Inhibitory neurons: 63.7;Oligodendrocyte precursor cells: 47.6;Oligodendrocytes: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Supported Vesicles,Lysosomes,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 14 "Vesicles, Lysosomes" Cytosol "CAB013514: AB_2533523, HPA064306: AB_2685240" "unprognostic (5.09e-3)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (9.75e-2)" "unprognostic (3.34e-3)" "unprognostic (1.17e-2)" "unprognostic (9.63e-2)" "unprognostic (8.80e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-2)" RRBP1 "ES/130, hES, p180" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 482.3" "Cell type enhanced" "Detected in all" "dendritic cells: 719.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 38.6;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 320000 "Cluster 29: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "HPA009026: AB_1079852, HPA011924: AB_1856476" "unprognostic (1.56e-3)" "unprognostic (2.26e-3)" "unprognostic (8.46e-2)" "prognostic favorable (1.41e-4)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (6.63e-2)" "unprognostic (9.21e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.38e-4)" RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.5;esophagus: 17.9;intestine: 19.0;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 172.9;Extravillous trophoblasts: 289.1;Plasma cells: 244.2;Undifferentiated cells: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 15: NK-cells - Unknown function" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 61: Plasma cells - Immunoglobulins & histones" 4 Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis, DNA damage, DNA repair" Oxidoreductase "Deafness, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 3 "Nucleoplasm, Cytosol" "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 89.9;skeletal muscle: 37.1" "Cell type enhanced" "Detected in all" "monocytes: 104.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 26.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Monocytes - Innate immune response" Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: AB_2680965, HPA074403: " "unprognostic (2.79e-1)" "unprognostic (7.65e-2)" "unprognostic (5.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.12e-8)" "unprognostic (2.64e-1)" "unprognostic (1.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (2.58e-2)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" "unprognostic (6.99e-3)" RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 279.1" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 934.5;Rod photoreceptor cells: 445.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" RTL1 "HUR1, Mar1, MART1, PEG11, SIRH2" ENSG00000254656 "Retrotransposon Gag like 1" A6NKG5 14 100879753-100903722 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.6;brain: 3.2;placenta: 2.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "melanoma: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 51.0" "Testis - Spermatogonia" "Low region specificity" "Detected in many" "HPA066979, HPA077601" Enhanced Approved Cytosol No NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "HPA066979: AB_2685759, HPA077601: " "unprognostic (1.61e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-1)" "unprognostic (1.42e-3)" "unprognostic (2.10e-1)" RTN1 NSP ENSG00000139970 "Reticulon 1" Q16799 14 59595976-59870776 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 435.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 479.1;Horizontal cells: 180.7;Inhibitory neurons: 377.2;Oligodendrocyte precursor cells: 176.4;Oligodendrocytes: 230.5" "Cancer enhanced" "Detected in many" "glioma: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.2;intermediate monocyte: 2.4;myeloid DC: 3.9" "Group enriched" "Detected in many" 15 "dendritic cells: 3.9;monocytes: 2.4" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 89.0" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002745, HPA040945, HPA044249" Enhanced Supported "Nuclear bodies,Endoplasmic reticulum" NA NA 150000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 1 "Endoplasmic reticulum" "Nuclear bodies" "CAB002745: , HPA040945: AB_2677217, HPA044249: AB_2678874" "unprognostic (9.40e-3)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (4.24e-2)" "unprognostic (3.04e-3)" "unprognostic (8.67e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (2.79e-1)" "prognostic favorable (3.69e-4)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (1.75e-1)" "unprognostic (6.71e-2)" "unprognostic (1.62e-2)" RTN2 "NSP2, NSPL1, SPG12" ENSG00000125744 "Reticulon 2" O75298 19 45485294-45497055 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 491.9;tongue: 199.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.3;Extravillous trophoblasts: 170.7;Skeletal myocytes: 114.2;Syncytiotrophoblasts: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.2;eosinophil: 2.6;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "dendritic cells: 1.6;granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034948, HPA078531" Approved Uncertain Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 4: Extravillous trophoblasts - Unknown function" Vesicles "HPA034948: AB_2674375, HPA078531: " "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (5.07e-3)" "unprognostic (1.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.89e-2)" "unprognostic (3.09e-1)" "unprognostic (6.44e-2)" "unprognostic (5.10e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.58e-6)" "unprognostic (4.34e-1)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 648.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1079.4" "Group enriched" "Detected in all" 6 "granulocytes: 1079.4;monocytes: 400.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 21: Neutrophils - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 7 "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 97.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 9 "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 84.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.8;Excitatory neurons: 13.7;Granulosa cells: 12.8;Muller glia cells: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 11: T-cells - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" RTP3 "LTM1, TMEM7, Z3CXXC3" ENSG00000163825 "Receptor transporter protein 3" Q9BQQ7 3 46494611-46500950 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 140 "liver: 115.0" "Cell type enriched" "Detected in some" 31 "Hepatocytes: 120.0" "Cancer enriched" "Detected in some" 5 "liver cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.7" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075932 Uncertain Mitochondria NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Hepatocytes - Metabolism" Mitochondria "HPA075932: " "unprognostic (2.09e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.11e-6)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" RTP4 "IFRG28, Z3CXXC4" ENSG00000136514 "Receptor transporter protein 4" Q96DX8 3 187368385-187372076 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064887, HPA071189" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 5 Nucleoplasm "HPA064887: AB_2685383, HPA071189: AB_2686357" "unprognostic (1.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (6.35e-2)" "unprognostic (3.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.78e-1)" "unprognostic (1.18e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (6.83e-4)" "unprognostic (1.34e-1)" "unprognostic (5.49e-2)" "unprognostic (3.44e-2)" "unprognostic (2.95e-2)" "prognostic favorable (4.35e-4)" "prognostic favorable (1.45e-4)" RTP5 "C2orf85, CXXC11, FLJ33590, Z3CXXC5" ENSG00000188011 "Receptor transporter protein 5 (putative)" Q14D33 2 241869600-241873823 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "brain: 49.1" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 3.9;Late spermatids: 6.0;Oligodendrocyte precursor cells: 16.5" "Cancer enriched" "Detected in single" 10 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - T-cells" "Low region specificity" "Detected in all" HPA050902 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Oligodendrocyte precursor - Unknown function" 49 "HPA050902: AB_2681268" "unprognostic (3.26e-2)" "unprognostic (5.38e-4)" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "unprognostic (9.40e-4)" "unprognostic (8.68e-3)" "unprognostic (2.04e-1)" "unprognostic (6.34e-4)" "unprognostic (3.30e-1)" "unprognostic (9.01e-3)" "unprognostic (3.91e-1)" "unprognostic (9.08e-8)" "unprognostic (1.81e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.72e-2)" RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 49 "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.7;endometrium 1: 6.0" "Group enriched" "Detected in some" 6 "Excitatory neurons: 161.9;Glandular and luminal cells: 162.0" "Cancer enriched" "Detected in single" 9 "endometrial cancer: 3.9" "Group enriched" "Detected in many" 5 "basal ganglia: 12.0;cerebral cortex: 14.4;hypothalamus: 5.2;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 6.6;ovarian cancer: 23.1;Uterine cancer: 13.5" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 14.4;hippocampal formation: 9.3" HPA027067 Approved NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "HPA027067: AB_10602127" "unprognostic (3.07e-3)" "unprognostic (3.02e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-3)" "unprognostic (6.13e-2)" "unprognostic (6.18e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-6)" "unprognostic (8.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.33e-4)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (6.22e-3)" RXFP3 "GPCR135, RLN3R1, RXFPR3, SALPR" ENSG00000182631 "Relaxin family peptide receptor 3" Q9NSD7 5 33936386-33938918 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027833 Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "HPA027833: AB_1849247" "unprognostic (1.93e-2)" "unprognostic (3.66e-1)" "unprognostic (2.89e-1)" "unprognostic (2.86e-1)" "unprognostic (9.68e-2)" "unprognostic (1.72e-1)" "unprognostic (8.67e-3)" RYK "D3S3195, JTK5, JTK5A, RYK1" ENSG00000163785 "Receptor like tyrosine kinase" P34925 3 134065303-134250859 "Enzymes, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034117, HPA045503, HPA075430, CAB080389" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" Cytosol "CAB034117: AB_2183048, CAB080389: , HPA045503: AB_2679353, HPA075430: AB_2732293" "unprognostic (7.84e-2)" "unprognostic (5.82e-2)" "unprognostic (2.22e-2)" "unprognostic (2.34e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (2.60e-2)" "unprognostic (6.59e-2)" "unprognostic (1.62e-1)" "unprognostic (1.07e-3)" "unprognostic (9.66e-2)" "unprognostic (2.42e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-1)" "unprognostic (3.43e-1)" "unprognostic (2.85e-2)" RYR1 "CCO, MHS, MHS1, PPP1R137, RYR" ENSG00000196218 "Ryanodine receptor 1" P21817 19 38433691-38595273 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 35 "skeletal muscle: 1097.4;tongue: 331.8" "Cell type enriched" "Detected in many" 9 "Skeletal myocytes: 445.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 3.3;granulocytes: 3.3;monocytes: 4.3" "Cancer enhanced" "Detected in many" "cervical cancer: 21.0" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 12.6" HPA056416 Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 46000 "Cluster 40: Monocytes - Innate immune response" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "Golgi apparatus, Vesicles" Cytosol "HPA056416: AB_2683121" "unprognostic (2.22e-3)" "unprognostic (1.91e-3)" "unprognostic (9.59e-2)" "unprognostic (5.34e-4)" "unprognostic (2.50e-1)" "unprognostic (6.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.20e-3)" "unprognostic (3.52e-1)" "unprognostic (2.35e-1)" "unprognostic (1.07e-5)" "unprognostic (1.13e-2)" "unprognostic (8.10e-2)" "unprognostic (6.62e-3)" "unprognostic (1.34e-1)" RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "heart muscle: 134.4" "Group enriched" "Detected in many" 12 "Cardiomyocytes: 2742.2;Excitatory neurons: 1274.9;Inhibitory neurons: 760.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA020028: AB_1856528" "unprognostic (5.23e-3)" "unprognostic (2.15e-2)" "unprognostic (5.02e-4)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (1.45e-3)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (0.00e+0)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.1;choroid plexus: 28.7;skeletal muscle: 23.3;tongue: 42.3" "Cell type enriched" "Detected in many" 4 "Astrocytes: 748.1" "Cancer enriched" "Detected in single" 4 "glioma: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 30.4" HPA062004 Approved Vesicles NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA062004: AB_2797267" "unprognostic (5.85e-2)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (8.03e-4)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.10e-2)" "unprognostic (8.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1711.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 4228.3;Distal enterocytes: 5741.5;Paneth cells: 4483.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2009.9;monocytes: 1239.0;T-cells: 1183.5" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 9 Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 257.8;Endothelial cells: 150.8;Lymphatic endothelial cells: 76.8;NK-cells: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1252.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 89.4;Early spermatids: 71.9;Late spermatids: 198.9;Syncytiotrophoblasts: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 44.9" "Group enriched" "Detected in many" 8 "granulocytes: 44.9;T-cells: 12.4" "Cancer enhanced" "Detected in many" "lymphoma: 30.8" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 59.7" "Cell type enhanced" "Detected in many" "B-cells: 63.9;dendritic cells: 39.9;Hofbauer cells: 37.3;monocytes: 62.9;NK-cells: 117.6;T-cells: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 45.8;lymphoma: 35.0;Myeloma: 24.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Prostate - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" 1 Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.6;brain: 33.3;skin 1: 14.1" "Cell type enriched" "Detected in some" 6 "NK-cells: 170.4" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 300.0;MAIT T-cell: 185.0;memory CD8 T-cell: 144.8;naive CD8 T-cell: 109.2" "Lineage enriched" "Detected in many" 7 "T-cells: 300.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: NK-cells - Adaptive immune response" 2 "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" SAA2-SAA4 ENSG00000255071 "SAA2-SAA4 readthrough" 11 18231423-18248635 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "liver: 123.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.0;Ciliated cells: 1.2;Ionocytes: 1.5" "Cancer enriched" "Detected in many" 13 "liver cancer: 39.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.4;head and neck cancer: 11.6" HPA060139 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA060139: AB_2684210" "prognostic favorable (4.56e-4)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-3)" "unprognostic (9.41e-3)" "unprognostic (1.96e-2)" "unprognostic (1.96e-1)" "unprognostic (8.27e-3)" "unprognostic (3.17e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (2.92e-8)" "unprognostic (1.92e-1)" "unprognostic (2.72e-1)" SACM1L "KIAA0851, SAC1" ENSG00000211456 "SAC1 like phosphatidylinositide phosphatase" Q9NTJ5 3 45689056-45745412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039573, HPA069869" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 82000 "Cluster 1: T-cells - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 26 "Nucleoplasm, Golgi apparatus" "HPA039573: AB_10674983, HPA069869: AB_2686216" "unprognostic (2.07e-1)" "unprognostic (4.08e-1)" "unprognostic (1.36e-3)" "unprognostic (1.14e-1)" "unprognostic (2.31e-2)" "unprognostic (4.34e-2)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" "unprognostic (8.54e-2)" "unprognostic (1.94e-2)" "unprognostic (1.22e-2)" "unprognostic (6.29e-3)" "prognostic favorable (5.47e-7)" "unprognostic (3.50e-1)" "unprognostic (1.62e-1)" "unprognostic (2.50e-1)" "unprognostic (1.33e-2)" SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.0;Inhibitory neurons: 266.6;Squamous epithelial cells: 49.4;Suprabasal keratinocytes: 62.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" SAMD8 "FLJ25082, SMSr" ENSG00000156671 "Sterile alpha motif domain containing 8" Q96LT4 10 75099586-75182123 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 19.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044402 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" "Endoplasmic reticulum, Cytosol" "HPA044402: " "unprognostic (4.32e-1)" "unprognostic (3.14e-1)" "unprognostic (3.24e-2)" "unprognostic (7.87e-2)" "unprognostic (3.37e-2)" "unprognostic (2.77e-2)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (5.29e-1)" "unprognostic (3.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (4.16e-3)" "unprognostic (3.89e-2)" "unprognostic (3.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.26e-3)" SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 1193.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Endoplasmic reticulum" "Rods & Rings" "HPA040400: AB_2676962" "unprognostic (1.11e-1)" "unprognostic (4.78e-2)" "unprognostic (4.27e-3)" "unprognostic (1.38e-3)" "unprognostic (7.86e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (8.03e-2)" "unprognostic (6.70e-3)" "unprognostic (1.06e-2)" "unprognostic (5.09e-2)" "unprognostic (3.88e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-1)" SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115193 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.4" "Cell type enhanced" "Detected in many" "Early spermatids: 159.3;Spermatocytes: 191.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55528611-55537133 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 28 "heart muscle: 84.3;tongue: 27.8" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 23.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 10.6" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Enhanced NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA030631: AB_10602088" "unprognostic (1.33e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-1)" "unprognostic (3.49e-1)" "unprognostic (5.43e-3)" "unprognostic (4.18e-3)" "unprognostic (2.08e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-1)" SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 31.4;tongue: 14.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.3" "Not detected" "Not detected" HPA078322 Approved Mitochondria NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 9 Mitochondria "HPA078322: AB_2732379" "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 381.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 296.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" SCAF11 "CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP" ENSG00000139218 "SR-related CTD associated factor 11" Q99590 12 45919131-45992120 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038862, HPA045456, HPA046345" Supported Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" Nucleoplasm "Nucleoli, Nuclear bodies" "HPA038862: AB_10672830, HPA045456: AB_2679331, HPA046345: AB_2679630" "unprognostic (2.83e-2)" "unprognostic (4.10e-2)" "unprognostic (2.01e-1)" "unprognostic (5.88e-2)" "unprognostic (1.19e-1)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (9.00e-2)" "unprognostic (1.37e-2)" "unprognostic (1.30e-2)" "unprognostic (4.10e-2)" "unprognostic (2.15e-2)" "unprognostic (6.30e-3)" "unprognostic (1.68e-1)" "unprognostic (2.76e-1)" "unprognostic (4.30e-2)" "unprognostic (4.13e-2)" SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 13 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (8.25e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-3)" "unprognostic (5.34e-3)" "unprognostic (2.60e-1)" "unprognostic (2.57e-3)" "unprognostic (5.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.92e-4)" "unprognostic (8.44e-3)" "unprognostic (7.56e-2)" "unprognostic (3.12e-2)" "unprognostic (4.99e-2)" SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 2 "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" SCAMP3 C1orf3 ENSG00000116521 "Secretory carrier membrane protein 3" O14828 1 155255979-155262430 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071167 Supported Vesicles NA NA 75000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 77: Plasma cells - Protein processing" 1 Vesicles "HPA071167: AB_2686352" "unprognostic (4.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-2)" "unprognostic (5.33e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (8.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (3.74e-2)" "unprognostic (8.46e-3)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (1.07e-1)" "unprognostic (7.18e-2)" SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905214-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 37: Glandular & Luminal cells - Unknown function" 16 "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: AB_10806501" "unprognostic (1.60e-1)" "unprognostic (3.62e-1)" "unprognostic (5.04e-2)" "prognostic favorable (4.40e-6)" "unprognostic (2.58e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.92e-5)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.55e-1)" "unprognostic (3.01e-3)" "unprognostic (5.66e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.16e-2)" "unprognostic (1.58e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-1)" SCAMP5 MGC24969 ENSG00000198794 "Secretory carrier membrane protein 5" Q8TAC9 15 74957219-75021495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 205.2;retina: 275.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.9;Cone photoreceptor cells: 168.2;dendritic cells: 96.5;Excitatory neurons: 72.5;Horizontal cells: 67.4;Inhibitory neurons: 95.1;Rod photoreceptor cells: 155.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 37 "plasmacytoid DC: 27.7" "Lineage enriched" "Detected in single" 37 "dendritic cells: 27.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 76.5" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046645 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 15 "HPA046645: AB_2679734" "unprognostic (1.37e-1)" "unprognostic (3.30e-1)" "unprognostic (1.80e-1)" "unprognostic (1.20e-2)" "unprognostic (2.74e-1)" "unprognostic (4.46e-2)" "unprognostic (2.56e-1)" "unprognostic (4.13e-1)" "unprognostic (2.34e-1)" "unprognostic (8.37e-2)" "prognostic favorable (5.67e-5)" "unprognostic (9.82e-2)" "prognostic favorable (1.34e-6)" "unprognostic (7.27e-2)" "unprognostic (3.01e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-2)" SCAP KIAA0199 ENSG00000114650 "SREBF chaperone" Q12770 3 47413681-47477126 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004713 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Mixed function" "HPA004713: AB_1079868" "unprognostic (4.02e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (4.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.74e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-2)" "unprognostic (7.10e-2)" "prognostic favorable (7.14e-4)" "unprognostic (4.07e-2)" "prognostic favorable (4.33e-5)" "unprognostic (3.15e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-3)" SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 226.3;Basal prostatic cells: 70.3;Collecting duct cells: 66.1;Secretory cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 87.1" "Group enriched" "Detected in many" 5 "Fibroblasts: 185.6;Leydig cells: 134.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "choroid plexus: 10.4" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 212 "dendritic cells: 21.1" "Group enriched" "Detected in some" 4 "Rhabdoid: 12.3;Sarcoma: 17.0" "Breast - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 25.7" HPA024661 Approved NA NA 1400000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" SCARB1 "CD36L1, CLA-1, CLA1, SR-BI, SRB1" ENSG00000073060 "Scavenger receptor class B member 1" Q8WTV0 12 124776856-124882668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adrenal gland: 964.5" "Cell type enhanced" "Detected in many" "Adipocytes: 144.9;Hepatocytes: 148.8;Kupffer cells: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 22.0" "Group enriched" "Detected in many" 6 "dendritic cells: 22.0;monocytes: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066285, CAB070124, HPA072449" Enhanced Approved "Vesicles,Lysosomes,Rods & Rings" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 5 Vesicles "Lysosomes, Rods & Rings" "CAB070124: AB_10107658, HPA066285: AB_2685649, HPA072449: AB_2732201" "unprognostic (9.70e-3)" "unprognostic (4.94e-3)" "unprognostic (1.32e-1)" "unprognostic (4.79e-2)" "unprognostic (1.65e-3)" "unprognostic (4.21e-3)" "prognostic unfavorable (1.83e-5)" "prognostic unfavorable (4.02e-4)" "unprognostic (2.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.49e-5)" "unprognostic (3.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 11.7;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.1;non-classical monocyte: 25.0;plasmacytoid DC: 28.8" "Group enriched" "Detected in all" 5 "dendritic cells: 28.8;granulocytes: 11.7;monocytes: 26.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA 9200 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Liver - Plasma proteins" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 5 Cytosol "CAB015415: AB_831511, HPA018014: AB_1852881" "prognostic unfavorable (2.82e-5)" "unprognostic (2.73e-2)" "unprognostic (4.09e-2)" "unprognostic (4.96e-2)" "unprognostic (4.17e-3)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-2)" "unprognostic (4.11e-2)" "unprognostic (1.67e-1)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (6.88e-2)" "unprognostic (5.06e-2)" "unprognostic (3.89e-2)" SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 13.3;Endometrial stromal cells: 16.2;Fibroblasts: 23.4;Leydig cells: 12.5;Peritubular cells: 16.3;Smooth muscle cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 580000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 32: Smooth muscle cells - Muscle contraction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: AB_10670287" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (2.29e-1)" "unprognostic (2.92e-1)" "unprognostic (7.68e-2)" "unprognostic (7.87e-2)" "unprognostic (8.27e-2)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.38e-3)" "unprognostic (3.18e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (4.28e-4)" SCART1 CD163c-alpha ENSG00000214279 "Scavenger receptor family member expressed on T cells 1" Q4G0T1 10 133453928-133523558 "Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.6;Horizontal cells: 3.1;Rod photoreceptor cells: 5.7;Skeletal myocytes: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA043101 Supported NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA043101: AB_10797026" "unprognostic (4.32e-2)" "unprognostic (2.15e-2)" "unprognostic (1.13e-2)" "unprognostic (2.40e-2)" "unprognostic (7.42e-2)" "unprognostic (8.20e-4)" "unprognostic (1.29e-3)" "unprognostic (4.28e-3)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (2.91e-1)" "unprognostic (2.24e-2)" "unprognostic (6.24e-5)" "unprognostic (8.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.03e-2)" "unprognostic (1.94e-1)" SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1689.1;Spermatocytes: 696.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 875.3" "Lineage enriched" "Detected in all" 26 "granulocytes: 875.3" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" SCD "FADS5, SCD1, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1190.8;brain: 976.3;liver: 566.0" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 499.0;Hepatocytes: 745.6;Kupffer cells: 696.5;Oligodendrocytes: 420.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 30: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Hepatocytes - Metabolism" 36 "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 151.8;brain: 287.4" "Group enriched" "Detected in many" 4 "Astrocytes: 235.6;Oligodendrocyte precursor cells: 837.7;Oligodendrocytes: 478.0" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favorable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.9" "Group enriched" "Detected in many" 6 "B-cells: 77.8;Hofbauer cells: 42.2;Kupffer cells: 116.7;Macrophages: 58.1;monocytes: 87.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 146.0;myeloid DC: 84.1;naive B-cell: 124.7;non-classical monocyte: 267.0" "Group enriched" "Detected in all" 8 "B-cells: 146.0;dendritic cells: 84.1;monocytes: 267.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.8;lymphoma: 16.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 3 "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCN11A "NaN, Nav1.9, SCN12A, SNS-2" ENSG00000168356 "Sodium voltage-gated channel alpha subunit 11" Q9UI33 3 38845764-39052157 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.9;placenta: 1.8" "Cell type enhanced" "Detected in some" "Adipocytes: 6.0;Astrocytes: 7.4;Early spermatids: 7.6;Late spermatids: 5.0;Spermatocytes: 18.4;Spermatogonia: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036746, HPA036747" Uncertain NA NA "Cluster 47: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 67: Spermatogonia - Spermatogenesis" "HPA036746: AB_10696785, HPA036747: AB_2675287" "unprognostic (6.11e-2)" "unprognostic (5.16e-1)" "unprognostic (1.66e-1)" "unprognostic (4.75e-2)" "unprognostic (4.21e-2)" "unprognostic (2.34e-2)" "unprognostic (2.79e-2)" "unprognostic (5.66e-2)" "unprognostic (4.44e-2)" "unprognostic (5.21e-2)" "unprognostic (2.30e-4)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (5.02e-2)" "unprognostic (2.95e-1)" "unprognostic (3.12e-2)" "unprognostic (8.30e-4)" SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.9;retina: 3.3" "Group enriched" "Detected in some" 10 "Excitatory neurons: 396.7;Inhibitory neurons: 474.6;Oligodendrocyte precursor cells: 649.5" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 70.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 425.4;Inhibitory neurons: 349.2;Oligodendrocyte precursor cells: 231.1" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.8" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "CAB022567: " "unprognostic (1.16e-1)" "unprognostic (3.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (1.18e-1)" "unprognostic (7.25e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" SCN3A Nav1.3 ENSG00000153253 "Sodium voltage-gated channel alpha subunit 3" Q9NY46 2 165087526-165204050 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;lymphoid tissue: 3.9" "Cell type enhanced" "Detected in many" "Early spermatids: 103.5;Excitatory neurons: 219.5;Inhibitory neurons: 161.8;Oligodendrocyte precursor cells: 336.3" "Cancer enriched" "Detected in some" 6 "glioma: 3.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 13.3;naive B-cell: 15.4" "Lineage enriched" "Detected in single" 32 "B-cells: 15.4" "Cancer enhanced" "Detected in many" "lung cancer: 9.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035396 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA035396: AB_2674607" "unprognostic (1.80e-3)" "unprognostic (1.84e-2)" "unprognostic (1.20e-3)" "unprognostic (1.50e-2)" "unprognostic (6.69e-2)" "unprognostic (1.10e-2)" "unprognostic (4.96e-4)" "unprognostic (2.46e-1)" "unprognostic (1.48e-1)" "unprognostic (1.90e-1)" "unprognostic (1.21e-4)" "unprognostic (4.55e-2)" "unprognostic (5.87e-3)" "unprognostic (2.88e-2)" "unprognostic (6.85e-2)" "unprognostic (2.66e-1)" "unprognostic (4.93e-2)" SCN3B "HSA243396, SCNB3" ENSG00000166257 "Sodium voltage-gated channel beta subunit 3" Q9NY72 11 123629187-123655244 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.8;pituitary gland: 27.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.6;Horizontal cells: 82.5;Inhibitory neurons: 34.0;Late spermatids: 33.0;Lymphatic endothelial cells: 73.2;Skeletal myocytes: 55.6" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041707 Approved "Intermediate filaments,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 93 "Intermediate filaments" Cytosol "HPA041707: AB_2732493" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (8.13e-4)" "unprognostic (3.93e-3)" "unprognostic (7.05e-2)" "unprognostic (3.29e-3)" "unprognostic (5.64e-2)" "unprognostic (3.34e-4)" "unprognostic (1.72e-1)" "unprognostic (1.13e-2)" "unprognostic (9.16e-4)" "unprognostic (4.01e-1)" "unprognostic (1.89e-4)" "unprognostic (2.01e-2)" "unprognostic (9.01e-2)" "unprognostic (8.23e-2)" "unprognostic (1.43e-2)" SCN4A "HYKPP, HYPP, Nav1.4, SkM1" ENSG00000007314 "Sodium voltage-gated channel alpha subunit 4" P35499 17 63938554-63972918 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 132.5;tongue: 51.9" "Group enriched" "Detected in some" 6 "Adipocytes: 40.2;Skeletal myocytes: 38.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;Sarcoma: 6.5" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" HPA070997 Uncertain "Golgi apparatus" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "HPA070997: " "unprognostic (2.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.57e-2)" "unprognostic (1.78e-3)" "unprognostic (2.80e-2)" "unprognostic (1.63e-2)" "unprognostic (3.87e-4)" "unprognostic (3.84e-3)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (3.15e-2)" "unprognostic (2.70e-2)" "unprognostic (4.38e-3)" "unprognostic (3.46e-1)" "unprognostic (4.15e-1)" "unprognostic (6.45e-2)" SCN4B LQT10 ENSG00000177098 "Sodium voltage-gated channel beta subunit 4" Q8IWT1 11 118133377-118152888 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;tongue: 54.6" "Cell type enhanced" "Detected in some" "Adipocytes: 10.1;Excitatory neurons: 17.6;Inhibitory neurons: 7.9;Late spermatids: 8.7;Sertoli cells: 19.0;Smooth muscle cells: 23.5" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.1" "Liver - Hepatic stellate cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 11 "basal ganglia: 816.5" "Region enriched" "Detected in many" 4 "basal ganglia: 174.4" HPA017293 Approved NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 65: Non-specific - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "HPA017293: AB_2184174" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.07e-1)" "unprognostic (9.82e-3)" "unprognostic (9.17e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.31e-4)" SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "heart muscle: 41.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 57.8;Cone photoreceptor cells: 34.0;Oocytes: 20.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.5;Sarcoma: 4.2" "Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 6.6" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 5 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.5;ovary: 38.5" "Cell type enriched" "Detected in many" 4 "Schwann cells: 709.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Rhabdoid: 19.2" "Colon - Enteric glia cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 10.0" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 17.5;pituitary gland: 6.5;retina: 7.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 325.4;Inhibitory neurons: 269.0;Oligodendrocyte precursor cells: 98.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.1" "Cell type enhanced" "Detected in many" "dendritic cells: 110.7;Exocrine glandular cells: 52.7;Hofbauer cells: 65.0;Langerhans cells: 53.3;Lymphatic endothelial cells: 59.2;Oligodendrocyte precursor cells: 125.5;Schwann cells: 89.5;Sertoli cells: 73.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.7" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 190.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 224.1;Alveolar cells type 2: 194.9;Distal enterocytes: 138.4;Glandular and luminal cells: 183.0;Intestinal goblet cells: 204.9;Salivary duct cells: 178.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 18 "choroid plexus: 243.0" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA012743 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 3 "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 80.5;intestine: 91.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.7;Club cells: 56.9;Distal enterocytes: 242.3;Ionocytes: 48.6;Salivary duct cells: 76.9;Suprabasal keratinocytes: 51.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Myeloma: 32.1;Sarcoma: 36.5;thyroid cancer: 9.6" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;testis: 34.6" "Cell type enhanced" "Detected in many" "Astrocytes: 10.2;Early spermatids: 10.5;Horizontal cells: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 21.8;Basal squamous epithelial cells: 11.7;Club cells: 26.0;Collecting duct cells: 40.8;Gastric mucus-secreting cells: 14.7;Glandular and luminal cells: 16.5;Ionocytes: 17.7;Salivary duct cells: 26.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 13.8" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 3 "HPA021565: AB_1856631, HPA021579: AB_1856632" "unprognostic (6.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.12e-3)" "unprognostic (1.09e-2)" "unprognostic (1.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.01e-2)" "unprognostic (3.02e-2)" "unprognostic (7.09e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-3)" "unprognostic (3.84e-2)" "prognostic favorable (9.69e-7)" "unprognostic (4.94e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.12e-2)" SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.8;pancreas: 66.0" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 29.6;Ductal cells: 96.2;Exocrine glandular cells: 95.2;Pancreatic endocrine cells: 28.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007269 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 477.8;liver: 472.9;skin 1: 433.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 232.8;Cholangiocytes: 259.5;Hepatocytes: 515.2;Squamous epithelial cells: 275.0;Suprabasal keratinocytes: 456.1;Syncytiotrophoblasts: 421.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 564.7" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 63100000 3100000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 445.9;thyroid gland: 411.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 181.0;Granulosa cells: 211.1;Hepatocytes: 227.8;Langerhans cells: 157.5;Ovarian stromal cells: 200.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.7" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA068532, HPA074427" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "CAB025123: , HPA068532: , HPA074427: " "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 61.3;Endometrial stromal cells: 58.6;Kupffer cells: 78.6;Late spermatids: 81.2;Oligodendrocyte precursor cells: 101.9" "Group enriched" "Detected in all" 5 "glioma: 115.2;melanoma: 102.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "skin cancer: 203.7" "Colon - Smooth muscle cells, Liver - Kupffer cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" Mitochondria Nucleoplasm "CAB025786: , HPA017087: AB_1857706, HPA048085: AB_2680256" "unprognostic (1.42e-3)" "unprognostic (5.52e-2)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (1.79e-3)" "unprognostic (2.83e-1)" "prognostic favorable (2.36e-4)" "unprognostic (9.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (6.45e-2)" "unprognostic (2.74e-1)" "unprognostic (9.80e-3)" "unprognostic (1.46e-1)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 398.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 602.0;Exocrine glandular cells: 496.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 320000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 5 "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 386.7;Distal tubular cells: 424.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA045727 Approved "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" SDK1 FLJ31425 ENSG00000146555 "Sidekick cell adhesion molecule 1" Q7Z5N4 7 3301252-4269000 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 12.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 214.8;Inhibitory neurons: 529.2;Late spermatids: 195.3;Microglial cells: 192.3;Oligodendrocyte precursor cells: 105.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011392 Approved Approved Cytosol NA NA 9500000 "Cluster 68: Non-specific - Protein processing" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA011392: AB_1856648" "unprognostic (2.39e-1)" "unprognostic (1.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.23e-1)" "unprognostic (9.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.16e-1)" "unprognostic (2.49e-2)" "unprognostic (7.84e-2)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (1.37e-1)" SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 50.4;lung: 33.4;skin 1: 60.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 213.2;Alveolar cells type 2: 467.7;Basal respiratory cells: 330.7;Ionocytes: 287.9;Suprabasal keratinocytes: 235.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 36 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 48 "B-cells: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.5" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 35: Respiratory epithelial cells - Unknown function" 9 "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 76.8;Hepatocytes: 104.8;Hofbauer cells: 94.0;Proximal tubular cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.9" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 77.6" "Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA 48000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favorable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favorable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 738.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 53: Non-specific - Glycosylation" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 4 "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 1454.0;Prostatic glandular cells: 905.5;Serous glandular cells: 745.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 868.3" "Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Plasma cells - Protein processing" 21 "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" SEC22A SEC22L2 ENSG00000121542 "SEC22 homolog A, vesicle trafficking protein" Q96IW7 3 123201927-123274136 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 65.2;Inhibitory neurons: 64.7;Oligodendrocytes: 69.8;Oocytes: 75.7;Spermatocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039127 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 88 "Golgi apparatus" Vesicles "HPA039127: " "unprognostic (2.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.96e-1)" "unprognostic (8.25e-3)" "unprognostic (2.16e-1)" "unprognostic (9.04e-2)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (6.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.05e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.25e-1)" SEC22B "ERS-24, SEC22L1" ENSG00000265808 "SEC22 homolog B, vesicle trafficking protein" O75396 1 120150898-120176520 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079017 Approved NA NA 91000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 45 "CAB079017: " "unprognostic (2.21e-1)" "unprognostic (2.29e-2)" "unprognostic (5.02e-2)" "unprognostic (8.52e-2)" "unprognostic (1.13e-1)" "unprognostic (7.88e-2)" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "prognostic favorable (4.58e-4)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.34e-4)" "unprognostic (5.80e-2)" "unprognostic (2.48e-1)" "unprognostic (1.52e-2)" "unprognostic (2.15e-1)" SEC22C "MGC13261, MGC5373, SEC22L3" ENSG00000093183 "SEC22 homolog C, vesicle trafficking protein" Q9BRL7 3 42547969-42601080 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031242 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 30: Granulocytes - Unknown function" 3 "Golgi apparatus" Nucleoplasm "HPA031242: " "unprognostic (1.68e-1)" "unprognostic (4.86e-2)" "unprognostic (1.01e-1)" "unprognostic (2.67e-1)" "unprognostic (9.37e-3)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.15e-1)" "unprognostic (3.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.35e-7)" "unprognostic (2.59e-1)" "unprognostic (3.30e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-3)" SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071705 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" SEC61B ENSG00000106803 "SEC61 translocon subunit beta" P60468 9 99222064-99230615 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 1651.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049407 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA049407: AB_2680750" "unprognostic (1.11e-1)" "unprognostic (5.99e-3)" "unprognostic (3.46e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.96e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.09e-1)" "unprognostic (6.67e-2)" "unprognostic (1.87e-2)" "unprognostic (2.90e-2)" "unprognostic (7.07e-2)" "unprognostic (1.22e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-1)" "unprognostic (6.87e-2)" "unprognostic (2.75e-1)" SEC61G SSS1 ENSG00000132432 "SEC61 translocon subunit gamma" P60059 7 54752250-54759974 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "glioma: 333.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053196 Uncertain NA NA 37000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 8 "HPA053196: AB_2682077" "unprognostic (1.39e-2)" "unprognostic (4.51e-3)" "unprognostic (5.26e-3)" "unprognostic (1.82e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.64e-7)" "prognostic unfavorable (3.85e-6)" "unprognostic (2.09e-2)" "unprognostic (2.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (6.60e-8)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (7.95e-3)" "unprognostic (8.43e-2)" SEC62 "Dtrp1, HTP1, TLOC1" ENSG00000008952 "SEC62 homolog, preprotein translocation factor" Q99442 3 169966635-169998373 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014059, HPA061450" Approved Approved "Endoplasmic reticulum,Intermediate filaments" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "Intermediate filaments" "HPA014059: AB_1858029, HPA061450: AB_2684524" "unprognostic (8.15e-2)" "unprognostic (6.84e-2)" "unprognostic (2.72e-1)" "unprognostic (4.93e-3)" "unprognostic (5.13e-1)" "unprognostic (1.10e-3)" "unprognostic (1.24e-1)" "unprognostic (4.04e-1)" "unprognostic (6.78e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 75: Serous glandular cells - Salivary secretion" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 87.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 86.3;Macrophages: 38.5;monocytes: 126.0;Mucus glandular cells: 48.3;Oocytes: 49.3;Proximal enterocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 155.2" "Group enriched" "Detected in many" 13 "granulocytes: 155.2;monocytes: 58.3" "Low cancer specificity" "Detected in many" "Stomach - Macrophages" "Low region specificity" "Detected in many" HPA051214 Approved "Secreted to blood" "No annotated function" NA NA 16000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 390.9" "Cell type enhanced" "Detected in all" "Plasma cells: 240.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" Other NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "HPA024267: AB_1856659" "unprognostic (4.94e-1)" "unprognostic (8.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-2)" "unprognostic (1.16e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-1)" "unprognostic (9.97e-2)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" "unprognostic (4.86e-1)" "unprognostic (3.31e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-2)" "unprognostic (1.25e-2)" SEL1L2 "C20orf50, DKFZp434C1826" ENSG00000101251 "SEL1L2 adaptor subunit of ERAD E3 ligase" Q5TEA6 20 13849247-13996443 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 6.9" "Group enriched" "Detected in some" 9 "Early spermatids: 191.8;Late spermatids: 166.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059121 Approved NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Early spermatids - Unknown function" "HPA059121: AB_2683911" "unprognostic (6.70e-2)" "unprognostic (1.64e-2)" "unprognostic (2.72e-3)" "unprognostic (2.19e-1)" "unprognostic (8.51e-2)" "unprognostic (5.33e-2)" "unprognostic (2.13e-2)" "unprognostic (2.54e-1)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (2.43e-2)" "unprognostic (3.62e-2)" "unprognostic (3.12e-2)" SEL1L3 KIAA0746 ENSG00000091490 "SEL1L family member 3" Q68CR1 4 25747433-25863760 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 124.7" "Cell type enhanced" "Detected in many" "dendritic cells: 426.1;Oligodendrocyte precursor cells: 120.7;Plasma cells: 272.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 175.6" "Group enriched" "Detected in many" 4 "memory B-cell: 42.1;naive B-cell: 42.0;plasmacytoid DC: 38.3" "Group enriched" "Detected in many" 4 "B-cells: 42.1;dendritic cells: 38.3" "Low cancer specificity" "Detected in many" "Breast - Plasma cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 129.1" "HPA039355, HPA040045, HPA058792" Approved Uncertain Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" Mitochondria "HPA039355: , HPA040045: AB_10796116, HPA058792: AB_2683822" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (3.06e-3)" "unprognostic (1.44e-2)" "unprognostic (2.43e-3)" "unprognostic (1.80e-1)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.33e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (5.11e-1)" "unprognostic (4.77e-2)" "unprognostic (7.21e-3)" "unprognostic (1.32e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" SELE "CD62E, ELAM, ELAM1, ESEL" ENSG00000007908 "Selectin E" P16581 1 169722640-169764705 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 54.0" "Cell type enriched" "Detected in many" 13 "Endothelial cells: 637.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB002143 Enhanced NA NA 8140000 180000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB002143: AB_563608" "unprognostic (2.39e-1)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (2.94e-1)" "unprognostic (3.63e-1)" "unprognostic (3.88e-1)" "unprognostic (9.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.56e-2)" "unprognostic (8.13e-3)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.55e-1)" SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395885 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 49: Non-specific - Transcription" "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891885 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 2749.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 326.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 326.8" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 50: Lymphoma - Unknown function" "Cluster 30: Granulocytes - Unknown function" 24 "Nucleoplasm, Cytosol" "HPA008196: AB_1856665" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-1)" "prognostic favorable (7.18e-4)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.02e-2)" "prognostic favorable (3.76e-4)" "unprognostic (2.75e-1)" "unprognostic (5.21e-2)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-2)" "unprognostic (8.43e-2)" "unprognostic (8.12e-2)" "unprognostic (9.35e-2)" "unprognostic (2.56e-3)" SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2030.1;liver: 6077.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 3136.6;Proximal enterocytes: 5404.0" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 182.2" "Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 2220000000 1800000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" SELENOS "AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP" ENSG00000131871 "Selenoprotein S" Q9BQE4 15 101270817-101277500 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 608.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 608.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010025 Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA010025: AB_1079900" "unprognostic (1.90e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.42e-2)" "unprognostic (3.74e-3)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (9.83e-2)" "prognostic favorable (5.19e-4)" "unprognostic (2.42e-3)" "unprognostic (4.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" "unprognostic (2.66e-2)" SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630436 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 541.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA039780: AB_10805594" "unprognostic (1.13e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (2.65e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-3)" "unprognostic (6.30e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-3)" "unprognostic (4.91e-2)" "unprognostic (4.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 148.8;lymphoid tissue: 225.9" "Cell type enhanced" "Detected in many" "B-cells: 216.9;dendritic cells: 367.1;Kupffer cells: 81.4;Macrophages: 66.8;NK-cells: 87.5;T-cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 34.0;lymphoma: 29.2;Myeloma: 15.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 4700000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" Cytosol "CAB002144: AB_563862, HPA051972: AB_2797242" "prognostic favorable (3.76e-4)" "prognostic favorable (2.25e-4)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (7.87e-3)" "prognostic favorable (6.43e-4)" "unprognostic (1.39e-3)" "unprognostic (3.43e-1)" "unprognostic (2.70e-3)" "prognostic favorable (3.14e-4)" "unprognostic (1.42e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (9.57e-2)" "unprognostic (1.01e-1)" SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 24.6;Endothelial cells: 48.0;Smooth muscle cells: 9.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 8.2" "Immune cell enhanced" "Detected in some" "basophil: 8.2;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.2;T-cells: 8.8" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.9" "Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.5" "Cell type enhanced" "Detected in many" "dendritic cells: 291.1;Kupffer cells: 82.9;Macrophages: 64.0;monocytes: 224.8;NK-cells: 163.3;T-cells: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 73.4;Myeloma: 231.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 2 Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 90.5;Mucus glandular cells: 69.2;Salivary duct cells: 101.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;eosinophil: 120.5;intermediate monocyte: 132.8;myeloid DC: 183.2;neutrophil: 211.4;non-classical monocyte: 76.6" "Group enriched" "Detected in all" 13 "dendritic cells: 183.2;granulocytes: 211.4;monocytes: 132.8" "Cancer enhanced" "Detected in many" "lymphoma: 47.3;Myeloma: 105.7" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 1 "HPA069136: AB_2686093" "unprognostic (1.90e-1)" "unprognostic (2.39e-2)" "unprognostic (4.24e-1)" "unprognostic (5.20e-2)" "unprognostic (8.04e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (3.51e-1)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (8.20e-4)" "unprognostic (8.77e-2)" "unprognostic (4.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.28e-2)" SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 120.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 80.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 17.0;naive B-cell: 15.0;neutrophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 14 "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 325.4" "Cell type enhanced" "Detected in many" "monocytes: 78.3;NK-cells: 104.8;Oligodendrocytes: 289.0;T-cells: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 47.6" "Adipose subcutaneous - T-cells, Colon - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.0;Inhibitory neurons: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064095 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA064095: AB_2732710" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Oligodendrocyte precursor cells: 1116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enhanced" "Detected in many" "skin cancer: 21.8" "Kidney - Podocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 13000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA004632: AB_1079905" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "unprognostic (6.67e-2)" "unprognostic (3.65e-1)" "prognostic favorable (2.45e-4)" "unprognostic (7.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (8.15e-2)" "prognostic favorable (3.66e-8)" "unprognostic (8.51e-3)" "unprognostic (1.27e-2)" "unprognostic (3.57e-1)" "unprognostic (3.01e-2)" SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 29.6;Oligodendrocyte precursor cells: 42.4" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 13.1;Kidney cancer: 23.3" "Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 58.2;brain: 54.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 125.3;Lymphatic endothelial cells: 130.8;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 289.7;Syncytiotrophoblasts: 350.4" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 203.7" "Liver - Sinusoid Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" SEMA6B "SEM-SEMA-Z, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.3" "Cell type enhanced" "Detected in many" "Adipocytes: 37.3;Endothelial cells: 41.4;Excitatory neurons: 29.6;Horizontal cells: 26.4;Inhibitory neurons: 29.0;Macrophages: 28.0;Oligodendrocyte precursor cells: 17.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 51.5" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.5;placenta: 41.7" "Cell type enhanced" "Detected in many" "Astrocytes: 69.0;Cone photoreceptor cells: 85.0;Excitatory neurons: 116.5;Inhibitory neurons: 306.8;Oligodendrocytes: 130.4" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 13.0" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 1100000 "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.7;lymphoid tissue: 58.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.6;dendritic cells: 120.4;Extravillous trophoblasts: 64.0;Rod photoreceptor cells: 51.5;Syncytiotrophoblasts: 173.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 22: Eosinophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" SEPSECS "SecS, SLA, SLA-p35, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 25.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Early spermatids - Spermatogenesis" 1 Vesicles "HPA070409: AB_2686265" "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" SERAC1 FLJ14917 ENSG00000122335 "Serine active site containing 1" Q96JX3 6 158109519-158168280 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 87.1;Late spermatids: 123.9;Oligodendrocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025715, HPA025716" Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Non-specific - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 11: Late spermatids - Unknown function" "HPA025715: AB_1856697, HPA025716: AB_2185128" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (6.92e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (2.50e-2)" "unprognostic (1.75e-1)" "unprognostic (1.61e-2)" "unprognostic (4.46e-1)" "unprognostic (5.98e-2)" "unprognostic (6.11e-3)" "unprognostic (4.21e-2)" "unprognostic (7.56e-2)" "unprognostic (1.34e-2)" "unprognostic (4.03e-2)" SERF1A "4F5, FAM2A, H4F5, SERF1, SMAM1" ENSG00000172058 "Small EDRK-rich factor 1A" O75920 5 70900669-70918530 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 62.6;testis: 42.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 1.9;Early spermatids: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075271 Uncertain "Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 11 "Nuclear bodies" "HPA075271: AB_2686740" "unprognostic (1.14e-1)" "unprognostic (3.00e-2)" "unprognostic (9.58e-2)" "unprognostic (3.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.81e-3)" "unprognostic (1.29e-3)" "unprognostic (1.40e-2)" "unprognostic (2.55e-2)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (4.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.98e-2)" "unprognostic (1.22e-2)" "unprognostic (9.53e-2)" SERF1B "FAM2B, H4F5C" ENSG00000205572 "Small EDRK-rich factor 1B" O75920 5 70025247-70043113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 150.1" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Early spermatids: 2.0;Late spermatids: 3.1;Schwann cells: 4.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA075271 Approved "Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 11 "Nuclear bodies" "HPA075271: AB_2686740" "unprognostic (1.00e-1)" "unprognostic (2.52e-4)" "unprognostic (2.60e-2)" "unprognostic (1.07e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (5.98e-2)" "unprognostic (4.92e-3)" "unprognostic (1.48e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-4)" "unprognostic (1.22e-1)" "unprognostic (2.16e-2)" "unprognostic (2.44e-2)" "unprognostic (7.82e-2)" "unprognostic (6.74e-2)" "unprognostic (3.52e-1)" SERINC1 "KIAA1253, TDE1L, TDE2, TMS-2" ENSG00000111897 "Serine incorporator 1" Q9NRX5 6 122443351-122471807 "Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035738, HPA035739" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" 5 Cytosol "HPA035738: AB_10672990, HPA035739: AB_10669536" "unprognostic (2.83e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.65e-1)" "unprognostic (2.84e-2)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.27e-2)" "unprognostic (9.07e-3)" "unprognostic (2.84e-1)" "unprognostic (5.50e-3)" "unprognostic (1.80e-3)" "unprognostic (9.22e-2)" "unprognostic (3.58e-1)" "unprognostic (1.00e-2)" SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 229.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 358.9;Cytotrophoblasts: 454.0;Distal enterocytes: 545.6;Ductal cells: 715.9;Proximal enterocytes: 402.0;Syncytiotrophoblasts: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" SERINC3 "AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1" ENSG00000132824 "Serine incorporator 3" Q13530 20 44496221-44522085 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048116 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 36: Late spermatids - Unknown function" 3 "HPA048116: AB_2680269" "unprognostic (3.16e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (2.60e-1)" "unprognostic (2.74e-1)" "unprognostic (7.34e-2)" "unprognostic (1.85e-3)" "unprognostic (6.26e-2)" "unprognostic (7.41e-2)" "unprognostic (3.11e-1)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-3)" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 193.2;Oligodendrocyte precursor cells: 209.4;Oligodendrocytes: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" SERP1 "FLJ43424, RAMP4" ENSG00000120742 "Stress associated endoplasmic reticulum protein 1" Q9Y6X1 3 150541998-150603228 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 37 "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (8.81e-3)" "unprognostic (2.35e-3)" "unprognostic (1.91e-1)" "unprognostic (7.29e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-2)" "unprognostic (2.35e-3)" "unprognostic (6.16e-2)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (2.55e-2)" "unprognostic (2.75e-2)" "unprognostic (4.75e-2)" "unprognostic (1.78e-1)" SERP2 "bA269C23.1, C13orf21" ENSG00000151778 "Stress associated endoplasmic reticulum protein family member 2" Q8N6R1 13 44373665-44397714 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.0;testis: 26.5" "Group enriched" "Detected in many" 12 "Early spermatids: 490.0;Late spermatids: 349.4" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enhanced" "Detected in single" "granulocytes: 2.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.1" "Heart muscle - Cardiomyocytes, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" 42 "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (6.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (2.06e-1)" "unprognostic (9.62e-2)" "unprognostic (1.72e-2)" "unprognostic (2.85e-1)" "unprognostic (3.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.34e-3)" "unprognostic (1.12e-2)" "prognostic favorable (1.94e-4)" "unprognostic (1.48e-1)" "unprognostic (6.60e-2)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 113 "liver: 338.3" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 217.4" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" "Blood coagulation" NA NA 3960000000 4700000000 "Cluster 31: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" 2 Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" SERPINB13 "HUR7, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 55.1;esophagus: 175.4;vagina: 131.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 104.8;Serous glandular cells: 59.7;Squamous epithelial cells: 183.7;Suprabasal keratinocytes: 646.4" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 9.3;cervical cancer: 32.3;Esophageal cancer: 15.6;Gallbladder cancer: 31.4;head and neck cancer: 27.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" SERTM1 C13orf36 ENSG00000180440 "Serine rich and transmembrane domain containing 1" A2A2V5 13 36674020-36697839 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.3;endometrium 1: 23.2;fallopian tube: 34.1" "Cell type enriched" "Detected in some" 4 "Mesothelial cells: 70.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 5.2;lung cancer: 1.6;prostate cancer: 6.6;thyroid cancer: 2.0" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054814, HPA070485" Enhanced Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 9: Endometrial stromal cells - Transcription" 13 Vesicles "HPA054814: AB_2682611, HPA070485: AB_2686272" "unprognostic (8.71e-2)" "unprognostic (2.11e-1)" "unprognostic (5.58e-3)" "unprognostic (4.66e-3)" "unprognostic (4.05e-3)" "unprognostic (5.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.63e-2)" "unprognostic (1.00e-8)" "unprognostic (2.51e-2)" "unprognostic (5.60e-2)" "unprognostic (4.44e-2)" SETD5 "FLJ10707, SETD5A" ENSG00000168137 "SET domain containing 5" Q9C0A6 3 9397615-9479240 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 247.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017093, HPA035574" Approved Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 Nucleoplasm "CAB017093: , HPA035574: AB_2674681" "unprognostic (6.46e-2)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.21e-4)" "unprognostic (5.52e-2)" "unprognostic (2.29e-1)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (6.65e-2)" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (5.15e-3)" SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 12 Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" SEZ6 ENSG00000063015 "Seizure related 6 homolog" Q53EL9 17 28954901-29006440 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 114.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 60.7;Cone photoreceptor cells: 22.1;Excitatory neurons: 15.3;Horizontal cells: 69.2;Inhibitory neurons: 23.3;Rod photoreceptor cells: 20.7" "Cancer enriched" "Detected in many" 11 "glioma: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.1;neutrophil: 2.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "lung cancer: 13.1;Neuroblastoma: 14.3;thyroid cancer: 21.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011777 Enhanced NA NA 310000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "HPA011777: AB_1856758" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (5.75e-3)" "unprognostic (5.33e-3)" "unprognostic (1.84e-2)" "unprognostic (1.76e-3)" "unprognostic (2.82e-2)" "unprognostic (2.22e-2)" "unprognostic (3.07e-1)" "unprognostic (4.75e-2)" "unprognostic (1.22e-3)" "unprognostic (3.15e-3)" "unprognostic (3.63e-6)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 48.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 214.4;Inhibitory neurons: 131.6;Oligodendrocyte precursor cells: 550.0" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.4" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 5 "Bone cancer: 23.7;lung cancer: 8.1;Neuroblastoma: 23.5" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 40: Monocytes - Innate immune response" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.5;pituitary gland: 89.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 229.8;Cone photoreceptor cells: 214.1;Horizontal cells: 249.9;Rod photoreceptor cells: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 33: Non-specific - ATP binding" "Cluster 18: Non-specific - Ribosome" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 3 "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" SFT2D1 "C6orf83, MGC19825, pRGR1" ENSG00000198818 "SFT2 domain containing 1" Q8WV19 6 166319728-166342576 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014677 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 35: Respiratory epithelial cells - Unknown function" 27 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA014677: AB_2238986" "unprognostic (8.45e-2)" "unprognostic (1.43e-3)" "unprognostic (2.29e-1)" "unprognostic (1.41e-2)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.47e-4)" "prognostic unfavorable (2.19e-5)" "unprognostic (3.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.68e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (4.20e-2)" "unprognostic (5.05e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.75e-2)" SFT2D2 "dJ747L4.C1.2, UNQ512" ENSG00000213064 "SFT2 domain containing 2" O95562 1 168225938-168253021 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 211.4;Late spermatids: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 53.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042207 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 40: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 28: Dendritic cells - Antigen presentation" 24 "HPA042207: AB_10794789" "unprognostic (4.34e-1)" "unprognostic (8.62e-2)" "unprognostic (1.78e-1)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (8.62e-3)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.37e-1)" "unprognostic (1.91e-1)" "unprognostic (8.54e-2)" "unprognostic (4.00e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-2)" "unprognostic (2.15e-3)" "unprognostic (9.22e-2)" "unprognostic (1.22e-3)" "unprognostic (1.71e-1)" SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.5" "Group enriched" "Detected in all" 5 "granulocytes: 99.5;T-cells: 36.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 14 Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.3;parathyroid gland: 12.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 21.1;Proximal tubular cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041241 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 189.4;Proximal enterocytes: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" 16 Mitochondria "HPA008028: AB_1079938, HPA048105: AB_2680265" "unprognostic (2.55e-1)" "unprognostic (3.32e-2)" "unprognostic (4.94e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (3.79e-4)" "unprognostic (3.84e-3)" "unprognostic (8.46e-2)" "unprognostic (1.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.04e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (3.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1;liver: 28.5" "Cell type enhanced" "Detected in all" "Astrocytes: 384.3;Late spermatids: 188.4" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 8 "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 146.2;skeletal muscle: 460.6;tongue: 208.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 76.5;Early spermatids: 115.6;Late spermatids: 671.7;Skeletal myocytes: 249.8" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 1.0;memory B-cell: 2.9;myeloid DC: 1.5;naive B-cell: 2.8;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 20 "B-cells: 2.9;dendritic cells: 1.5;monocytes: 1.4" "Cancer enriched" "Detected in single" 35 "Sarcoma: 23.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblast_2, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Late spermatids - Spermatogenesis" 6 "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 101.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.9;Late spermatids: 199.4;Skeletal myocytes: 115.1" "Cancer enhanced" "Detected in all" "glioma: 56.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 10 Cytosol "HPA011422: AB_1856795, HPA058656: AB_2683790" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-3)" "unprognostic (9.80e-2)" "unprognostic (3.42e-2)" "unprognostic (3.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.84e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.53e-6)" "unprognostic (3.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (7.61e-4)" SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ovarian stromal cells: 175.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.5;naive B-cell: 6.7" "Group enriched" "Detected in many" 4 "B-cells: 6.7;T-cells: 2.1" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 34: B-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 114.6;skeletal muscle: 152.5;tongue: 138.4" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 165.7;Skeletal myocytes: 78.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.7" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007476 Enhanced NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" 6 "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" SGCZ ZSG1 ENSG00000185053 "Sarcoglycan zeta" Q96LD1 8 14084845-15238431 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "ovary: 1.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 459.6;Inhibitory neurons: 2201.7;Oligodendrocyte precursor cells: 1158.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017585 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Neurons - Synaptic function" "HPA017585: AB_1856799" "unprognostic (3.83e-1)" "unprognostic (1.41e-1)" "unprognostic (5.87e-4)" "unprognostic (1.21e-1)" SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 147.9;Microglial cells: 219.2;Oligodendrocyte precursor cells: 293.8;Oligodendrocytes: 392.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Oligodendrocyte precursor - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.3;Alveolar cells type 2: 128.7;Ciliated cells: 104.5;Early spermatids: 94.6;Glandular and luminal cells: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015076, HPA015541" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Golgi apparatus" Nucleoplasm "HPA015076: AB_1857298, HPA015541: " "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815905-70895816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 138.6" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 45: Non-specific - Mixed function" 29 "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm "HPA053149: AB_2682057, HPA064908: AB_2797270" "unprognostic (1.57e-2)" "unprognostic (1.04e-2)" "unprognostic (5.40e-3)" "unprognostic (7.82e-2)" "unprognostic (9.09e-2)" "unprognostic (4.30e-2)" "unprognostic (6.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.64e-1)" "unprognostic (7.41e-2)" "unprognostic (1.51e-1)" "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-3)" SGSM3 "DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3" ENSG00000100359 "Small G protein signaling modulator 3" Q96HU1 22 40370591-40410289 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 112.6;Intestinal goblet cells: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048980 Approved Supported "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" "HPA048980: AB_2680585" "unprognostic (4.63e-2)" "unprognostic (7.51e-3)" "unprognostic (3.02e-2)" "prognostic favorable (4.47e-5)" "unprognostic (1.81e-1)" "unprognostic (6.83e-3)" "unprognostic (5.70e-3)" "unprognostic (7.53e-2)" "unprognostic (3.57e-1)" "unprognostic (5.67e-2)" "unprognostic (1.71e-3)" "unprognostic (1.93e-1)" "unprognostic (2.97e-1)" "unprognostic (4.08e-3)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.98e-3)" SH3TC1 FLJ20356 ENSG00000125089 "SH3 domain and tetratricopeptide repeats 1" Q8TE82 4 8182072-8241803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 94.6" "Cell type enhanced" "Detected in many" "dendritic cells: 68.3;Kupffer cells: 35.6;Macrophages: 38.3;monocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.8" "Group enriched" "Detected in all" 5 "B-cells: 8.8;dendritic cells: 28.8;monocytes: 25.2" "Cancer enhanced" "Detected in many" "lymphoma: 52.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038132, HPA056807" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 71: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA038132: AB_10673041, HPA056807: AB_2683239" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "unprognostic (1.61e-3)" "unprognostic (5.46e-2)" "unprognostic (2.26e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (8.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.46e-1)" "unprognostic (3.77e-3)" "unprognostic (1.15e-2)" "unprognostic (4.29e-2)" SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.1;skeletal muscle: 13.7;thyroid gland: 20.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.1;Breast glandular cells: 19.2;granulocytes: 20.3;Oligodendrocytes: 10.2;Skeletal myocytes: 24.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 20.8" "Kidney - Podocytes, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" 1 Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 15.0;kidney: 20.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 6.1;Endothelial cells: 4.3;Fibroblasts: 20.4;Mesothelial cells: 16.9;Smooth muscle cells: 4.7" "Cancer enhanced" "Detected in many" "lung cancer: 7.6;renal cancer: 7.8" "Group enriched" "Detected in all" 5 "midbrain: 29.0;thalamus: 19.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 18.1;Neuroblastoma: 17.8;Sarcoma: 19.7" "Breast - Endothelial cells, Colon - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in all" 5 "spinal cord: 30.5" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 53: Fibroblasts - ECM organization" 5 Cytosol "Lipid droplets" "HPA054754: AB_2682593" "unprognostic (9.04e-3)" "unprognostic (3.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.26e-1)" "unprognostic (6.78e-3)" "unprognostic (1.26e-2)" "unprognostic (2.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-3)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (5.32e-2)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.99e-3)" SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 212.0" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 42.9" "Cancer enhanced" "Detected in all" "glioma: 49.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 8 "HPA061273: AB_2684460, HPA067885: " "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (1.48e-3)" "unprognostic (2.12e-3)" "unprognostic (6.59e-2)" "unprognostic (8.29e-3)" "unprognostic (7.06e-2)" "unprognostic (5.00e-2)" "unprognostic (2.32e-1)" "unprognostic (1.44e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" SHISA5 "hShisa5, SCOTIN" ENSG00000164054 "Shisa family member 5" Q8N114 3 48467798-48504826 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 292.4;Extravillous trophoblasts: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042295 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA042295: AB_10794794" "unprognostic (3.52e-3)" "unprognostic (4.79e-2)" "unprognostic (1.71e-1)" "unprognostic (3.98e-2)" "unprognostic (8.58e-3)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.72e-6)" "unprognostic (3.82e-3)" "unprognostic (8.76e-3)" "unprognostic (1.21e-3)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.64e-5)" "unprognostic (1.11e-1)" "unprognostic (6.08e-3)" "unprognostic (3.81e-3)" "unprognostic (1.74e-2)" SHISA6 FLJ45455 ENSG00000188803 "Shisa family member 6" Q6ZSJ9 17 11241213-11564063 "Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;cervix: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 47.7;Excitatory neurons: 26.5;Inhibitory neurons: 173.5;Oligodendrocyte precursor cells: 72.6;Peritubular cells: 29.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.7;thyroid cancer: 1.9" "Colon - Fibroblasts" "Low region specificity" "Detected in all" HPA023440 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 20 "Nucleoplasm, Plasma membrane" "HPA023440: AB_1848945" "unprognostic (1.70e-1)" "unprognostic (2.78e-2)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "prognostic unfavorable (8.41e-4)" "unprognostic (3.11e-2)" "unprognostic (1.71e-1)" "unprognostic (8.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (9.63e-2)" "unprognostic (1.27e-1)" "unprognostic (2.40e-4)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.20e-2)" "unprognostic (2.47e-2)" SHISA7 ENSG00000187902 "Shisa family member 7" A6NL88 19 55428740-55443300 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 26.4" "Group enriched" "Detected in some" 14 "Excitatory neurons: 18.7;Horizontal cells: 10.1;Inhibitory neurons: 15.4;Oligodendrocyte precursor cells: 21.7;Oligodendrocytes: 15.0" "Cancer enriched" "Detected in single" 9 "glioma: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.7;Neuroblastoma: 2.0" "Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058935 Uncertain Approved Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA058935: AB_2683857" "unprognostic (3.98e-2)" "unprognostic (5.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.28e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.08e-1)" "unprognostic (4.40e-1)" "unprognostic (7.17e-2)" "unprognostic (2.11e-3)" "unprognostic (1.22e-2)" "unprognostic (6.87e-7)" "unprognostic (7.53e-3)" "unprognostic (2.82e-1)" "unprognostic (3.29e-4)" "unprognostic (4.04e-1)" SHISA8 "C22orf17, Orf26" ENSG00000234965 "Shisa family member 8" B8ZZ34 22 41909543-41915074 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 65.8" "Group enriched" "Detected in some" 7 "Horizontal cells: 137.2;Oocytes: 222.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 8 "cerebellum: 103.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebellum: 7.8;olfactory bulb: 15.7;white matter: 4.0" "Low region specificity" "Detected in all" HPA059173 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" "HPA059173: AB_2683938" "unprognostic (8.76e-2)" "unprognostic (2.98e-4)" "unprognostic (1.03e-1)" "prognostic favorable (2.76e-4)" "unprognostic (4.42e-2)" "unprognostic (1.45e-3)" "unprognostic (4.40e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.12e-1)" "unprognostic (8.59e-2)" "unprognostic (2.60e-2)" "unprognostic (6.22e-4)" "unprognostic (7.84e-2)" SHISA9 ENSG00000237515 "Shisa family member 9" B4DS77 16 12901598-13240416 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.6" "Group enriched" "Detected in some" 10 "Excitatory neurons: 255.8;Inhibitory neurons: 411.1;Oligodendrocyte precursor cells: 597.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.0" "Colon - Enteric glia cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072399 Approved Vesicles,Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" "Vesicles, Cytosol" "HPA072399: AB_2686517" "unprognostic (1.88e-2)" "unprognostic (3.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.69e-5)" "unprognostic (2.23e-2)" "unprognostic (2.03e-2)" "unprognostic (5.90e-5)" "unprognostic (1.50e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.53e-4)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (6.66e-2)" "unprognostic (1.26e-2)" SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.5;endometrium 1: 32.5;smooth muscle: 28.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.4;Endometrial stromal cells: 4.2;Excitatory neurons: 5.7;Inhibitory neurons: 11.7;Oocytes: 10.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 24 "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (4.07e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (6.54e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.10e-3)" "unprognostic (1.93e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (1.51e-7)" "unprognostic (1.48e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-4)" "unprognostic (1.10e-4)" SHISAL2A "FAM159A, MGC52498" ENSG00000182183 "Shisa like 2A" Q6UWV7 1 52633168-52669683 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 3.6;lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "B-cells: 33.1;NK-cells: 19.9;Plasma cells: 9.4;T-cells: 19.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 6 "hypothalamus: 18.1" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 10.1;NK-cells: 5.9;T-cells: 7.0" "Group enriched" "Detected in some" 9 "Leukemia: 1.3;lymphoma: 3.3;Myeloma: 4.8" "Adipose visceral - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enhanced" "Detected in some" "hypothalamus: 4.0" "Low region specificity" "Detected in many" HPA030744 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 2 "HPA030744: AB_10963060" "unprognostic (7.94e-6)" "unprognostic (8.50e-3)" "unprognostic (8.29e-3)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (9.67e-4)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (2.22e-2)" "unprognostic (4.45e-2)" "unprognostic (2.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-3)" "unprognostic (7.27e-2)" "unprognostic (2.79e-1)" "unprognostic (6.50e-2)" "unprognostic (2.64e-2)" SHISAL2B FAM159B ENSG00000145642 "Shisa like 2B" A6NKW6 5 64690442-64718190 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "brain: 3.1;pancreas: 4.8;stomach 1: 2.8" "Cell type enriched" "Detected in some" 8 "Pancreatic endocrine cells: 27.2" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 3.9" "Region enhanced" "Detected in many" "hypothalamus: 6.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Rhabdoid: 6.8" "Pancreas - Beta cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA011778 Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA011778: AB_1848382" "unprognostic (5.83e-2)" "unprognostic (9.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.84e-2)" "unprognostic (3.25e-1)" "unprognostic (5.01e-2)" "unprognostic (1.49e-1)" "unprognostic (9.12e-2)" "unprognostic (2.97e-1)" "unprognostic (4.84e-2)" "unprognostic (5.36e-5)" "unprognostic (1.44e-1)" "unprognostic (1.98e-1)" "unprognostic (5.60e-1)" "unprognostic (6.99e-2)" SHLD2 "bA163M19.1, FAM35A, FAM35A1, MGC5560, RINN2" ENSG00000122376 "Shieldin complex subunit 2" Q86V20 10 87094161-87191465 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036582, HPA057506" Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 18: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm "Actin filaments" "HPA036582: AB_10670233, HPA057506: " "unprognostic (1.08e-1)" "unprognostic (2.72e-1)" "prognostic favorable (6.06e-4)" "unprognostic (1.77e-1)" "prognostic favorable (3.09e-4)" "unprognostic (5.34e-2)" "unprognostic (2.68e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (8.20e-2)" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (1.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" "unprognostic (6.44e-3)" "unprognostic (3.61e-2)" SHOC1 "C9orf84, FLJ32779, MZIP2, Zip2" ENSG00000165181 "Shortage in chiasmata 1" Q5VXU9 9 111686171-111795008 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Meiosis "DNA-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.3" "Cell type enhanced" "Detected in some" "Early spermatids: 141.1;Microglial cells: 24.2;Oligodendrocyte precursor cells: 31.1;Spermatocytes: 95.6" "Cancer enhanced" "Detected in some" "cervical cancer: 0.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.8" "Kidney - Intercalated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052214 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 18: Early spermatids - Unknown function" Nucleoplasm "Nuclear bodies" "HPA052214: " "unprognostic (2.63e-1)" "unprognostic (1.83e-4)" "unprognostic (9.12e-2)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (9.05e-2)" "unprognostic (5.02e-2)" "unprognostic (6.22e-2)" "unprognostic (1.65e-1)" "unprognostic (8.14e-2)" "unprognostic (2.30e-1)" "unprognostic (8.33e-5)" "unprognostic (6.93e-2)" "unprognostic (2.84e-1)" "unprognostic (3.77e-1)" "unprognostic (7.31e-2)" SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078496 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 150 "intestine: 530.0" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 1115.4" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;prostate cancer: 1.7" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA011897 Enhanced NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" SIDT1 "FLJ20174, SID-1" ENSG00000072858 "SID1 transmembrane family member 1" Q9NXL6 3 113532555-113629575 "Predicted membrane proteins, Transporters" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 10.5" "Cell type enhanced" "Detected in many" "B-cells: 41.8;dendritic cells: 163.1;Excitatory neurons: 113.9;Inhibitory neurons: 83.2" "Cancer enhanced" "Detected in many" "breast cancer: 5.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 33.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 6.2;Myeloma: 7.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035862 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA035862: AB_10671110" "unprognostic (4.23e-1)" "prognostic favorable (3.78e-4)" "unprognostic (3.43e-3)" "unprognostic (1.33e-3)" "unprognostic (2.28e-1)" "unprognostic (6.64e-4)" "unprognostic (2.93e-4)" "unprognostic (1.50e-1)" "unprognostic (4.02e-1)" "unprognostic (3.29e-3)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (2.50e-1)" "unprognostic (3.02e-1)" "unprognostic (5.86e-2)" "unprognostic (1.32e-2)" "prognostic favorable (4.09e-5)" SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178736-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 69.1;monocytes: 165.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 83.6;non-classical monocyte: 152.0" "Lineage enriched" "Detected in all" 7 "monocytes: 152.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA052352: AB_2681797" "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" "unprognostic (9.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (2.67e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (4.18e-5)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (5.22e-3)" SIGIRR "IL-1R8, TIR8" ENSG00000185187 "Single Ig and TIR domain containing" Q6IA17 11 405716-417455 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 427.9;Proximal tubular cells: 607.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023188 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "Nucleoli fibrillar center, Cytosol" "HPA023188: AB_1856856" "unprognostic (6.21e-3)" "prognostic favorable (7.44e-5)" "unprognostic (7.30e-2)" "prognostic favorable (1.34e-5)" "unprognostic (6.85e-2)" "prognostic favorable (9.08e-4)" "unprognostic (4.03e-1)" "unprognostic (1.39e-2)" "unprognostic (8.44e-2)" "unprognostic (1.67e-1)" "unprognostic (2.32e-2)" "unprognostic (1.31e-1)" "prognostic favorable (7.61e-6)" "unprognostic (1.00e-3)" "unprognostic (1.76e-1)" "unprognostic (7.63e-2)" "prognostic favorable (1.54e-5)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Hofbauer cells: 76.4;Kupffer cells: 63.6;Macrophages: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" "Cell adhesion" NA NA 260000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 37.5" "Cell type enhanced" "Detected in some" "B-cells: 31.9;Kupffer cells: 96.7;Macrophages: 64.4;monocytes: 184.9;Schwann cells: 25.0" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 767.4;intermediate monocyte: 252.2;non-classical monocyte: 542.7" "Group enriched" "Detected in many" 16 "granulocytes: 767.4;monocytes: 542.7" "Group enriched" "Detected in many" 6 "Leukemia: 10.6;lymphoma: 31.2" "Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.4;ovary: 53.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 64.6;Ovarian stromal cells: 90.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.4;monocytes: 1.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51639478-51646825 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.0;lymphoid tissue: 27.0" "Group enriched" "Detected in some" 4 "Hofbauer cells: 23.3;Kupffer cells: 52.3;Macrophages: 17.7;monocytes: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.8;intermediate monocyte: 71.1;myeloid DC: 34.7;neutrophil: 80.0;non-classical monocyte: 58.8" "Group enriched" "Detected in many" 5 "dendritic cells: 34.7;granulocytes: 80.0;monocytes: 71.1" "Cancer enhanced" "Detected in single" "Leukemia: 3.2" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" SIGLEC15 "CD33L3, HsT1361" ENSG00000197046 "Sialic acid binding Ig like lectin 15" Q6ZMC9 18 45825675-45844094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.6;intestine: 2.9;stomach 1: 1.2;urinary bladder: 1.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.7;Cholangiocytes: 1.9;Hofbauer cells: 9.2;Langerhans cells: 2.7;Macrophages: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "classical monocyte: 3.0;myeloid DC: 1.0" "Group enriched" "Detected in many" 21 "dendritic cells: 1.0;monocytes: 3.0" "Cancer enhanced" "Detected in many" "Brain cancer: 11.3;thyroid cancer: 12.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053509 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA053509: " "unprognostic (3.89e-3)" "unprognostic (1.87e-2)" "unprognostic (1.77e-1)" "unprognostic (7.18e-3)" "unprognostic (2.27e-1)" "unprognostic (8.07e-2)" "unprognostic (5.91e-2)" "unprognostic (2.71e-1)" "unprognostic (9.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-2)" "unprognostic (7.65e-2)" "unprognostic (6.55e-2)" "unprognostic (1.42e-1)" "unprognostic (6.06e-2)" "unprognostic (4.40e-2)" "prognostic favorable (9.14e-5)" SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000268500 "Sialic acid binding Ig like lectin 5" O15389 19 51610960-51630401 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 28.9;lymphoid tissue: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 9.5" "Group enriched" "Detected in many" 4 "neutrophil: 284.6;non-classical monocyte: 96.2" "Group enriched" "Detected in many" 6 "granulocytes: 284.6;monocytes: 96.2" "Group enriched" "Detected in some" 7 "Leukemia: 6.0;lymphoma: 1.6" HPA009085 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" 5 "HPA009085: AB_1079965" SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 103.1" "Group enriched" "Detected in some" 12 "Cytotrophoblasts: 172.9;granulocytes: 226.4;Syncytiotrophoblasts: 322.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 7.2;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 9 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Group enriched" "Detected in some" 5 "Bladder cancer: 7.8;colorectal cancer: 11.8;Leukemia: 25.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Skin - Mast cells" "Low region specificity" "Detected in some" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" "Cell adhesion" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Placenta - Pregnancy" "Cluster 48: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 36.2;Kupffer cells: 60.6;Macrophages: 29.8;NK-cells: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 3.5;Myeloma: 4.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA075513, CAB080396" Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 2600000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane" Vesicles "CAB080396: , HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 21 "granulocytes: 32.7;Kupffer cells: 12.8;Macrophages: 10.3;Microglial cells: 10.7" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.9" "Lineage enriched" "Detected in single" 706 "granulocytes: 290.9" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.4" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Pancreas - Macrophages, Skin - Mast cells" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 1 Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 43.1;Kupffer cells: 31.8;Langerhans cells: 19.8;Macrophages: 24.6;monocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 199.2;intermediate monocyte: 182.7;myeloid DC: 169.3;neutrophil: 212.9;non-classical monocyte: 122.4" "Group enriched" "Detected in many" 13 "dendritic cells: 169.3;granulocytes: 212.9;monocytes: 199.2" "Group enriched" "Detected in some" 7 "Leukemia: 1.9;Myeloma: 3.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA010682, CAB080397" Approved NA NA 270000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 3 "CAB080397: , HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" SIGLECL1 "C19orf75, FLJ40235, SIGLEC23P, SIGLECP7" ENSG00000179213 "SIGLEC family like 1" Q8N7X8 19 51246348-51269330 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 67 "testis: 19.9" "Group enriched" "Detected in some" 11 "Early spermatids: 55.9;Late spermatids: 67.1;Spermatocytes: 62.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Testis - Early spermatids" HPA079471 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA079471: " "unprognostic (5.41e-2)" SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 100.9;Hepatocytes: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 50: Connective tissue cells - ECM organization" 2 "CAB013470: AB_2533521, HPA018002: AB_1854802, HPA024071: AB_1854803" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (8.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.89e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.42e-4)" SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427131 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9.7;Collecting duct cells: 11.7;Glandular and luminal cells: 8.5;Suprabasal keratinocytes: 21.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Nucleoplasm Vesicles "CAB023801: , HPA038211: AB_2675894, HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 107.4;Excitatory neurons: 210.3;Inhibitory neurons: 126.7;Oligodendrocytes: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 3 "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" SIK3 "FLJ12240, KIAA0999, L19, QSK" ENSG00000160584 "SIK family kinase 3" Q9Y2K2 11 116843402-117098437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 356.1;Excitatory neurons: 371.4;Inhibitory neurons: 383.2;Oligodendrocyte precursor cells: 429.7;Oligodendrocytes: 1563.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045245, HPA048161" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Non-specific - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA045245: AB_2679270, HPA048161: AB_2680293" "unprognostic (3.19e-2)" "unprognostic (3.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-2)" "unprognostic (1.28e-3)" "unprognostic (1.89e-1)" "prognostic favorable (1.12e-5)" "unprognostic (1.82e-1)" "unprognostic (6.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" SIRPA "BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2" ENSG00000198053 "Signal regulatory protein alpha" P78324 20 1894167-1940592 "CD markers, Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.3" "Cell type enhanced" "Detected in many" "Astrocytes: 131.0;Excitatory neurons: 84.5;Hofbauer cells: 100.3;Macrophages: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 24.1;eosinophil: 48.7;myeloid DC: 13.9;neutrophil: 50.9" "Group enriched" "Detected in many" 150 "dendritic cells: 13.9;granulocytes: 50.9;monocytes: 24.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 121.9" "Adipose subcutaneous - Macrophages, Testis - Spermatogonia" "CAB002776, CAB015122, HPA054437, HPA058511" Enhanced NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" "CAB002776: , CAB015122: AB_677430, HPA054437: AB_2682488, HPA058511: AB_2683738" "unprognostic (9.78e-2)" "unprognostic (2.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.23e-1)" "unprognostic (5.56e-2)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (4.19e-3)" "unprognostic (3.48e-2)" "unprognostic (2.84e-3)" "unprognostic (3.69e-1)" "unprognostic (3.33e-2)" "unprognostic (2.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.55e-2)" "unprognostic (3.55e-2)" "unprognostic (2.24e-2)" SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.7;lung: 18.8;lymphoid tissue: 27.8" "Group enriched" "Detected in some" 8 "dendritic cells: 35.5;Hofbauer cells: 29.3;Kupffer cells: 44.1;Macrophages: 30.4;monocytes: 57.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1606.1" "Group enriched" "Detected in all" 6 "granulocytes: 1606.1;monocytes: 503.9" "Cancer enhanced" "Detected in many" "Leukemia: 18.6;thyroid cancer: 23.3" "Adipose subcutaneous - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 1 Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8" "Group enriched" "Detected in some" 8 "Hofbauer cells: 7.9;Kupffer cells: 14.7;Langerhans cells: 4.0;Macrophages: 11.5;Microglial cells: 13.4;monocytes: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.6;non-classical monocyte: 24.5" "Group enriched" "Detected in many" 331 "dendritic cells: 21.1;granulocytes: 69.6;monocytes: 51.1" "Cancer enhanced" "Detected in some" "Leukemia: 4.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650931 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 91.6" "Group enriched" "Detected in some" 7 "B-cells: 79.8;dendritic cells: 38.9;Plasma cells: 21.4;T-cells: 79.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 203.6;memory B-cell: 215.4;memory CD4 T-cell: 250.7;memory CD8 T-cell: 223.7;naive B-cell: 193.3;naive CD4 T-cell: 171.4;naive CD8 T-cell: 170.2;plasmacytoid DC: 202.0;T-reg: 354.3" "Group enriched" "Detected in many" 56 "B-cells: 215.4;dendritic cells: 202.0;T-cells: 354.3" "Group enriched" "Detected in some" 9 "Leukemia: 23.7;lymphoma: 82.2" "Colon - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018506 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" 10 "HPA018506: AB_2669896" "unprognostic (4.28e-3)" "prognostic favorable (6.56e-4)" "unprognostic (8.01e-3)" "prognostic favorable (1.94e-6)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-4)" "unprognostic (1.75e-2)" "unprognostic (9.34e-3)" "prognostic favorable (8.17e-4)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (8.87e-2)" "unprognostic (6.34e-2)" SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647044 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 61.9" "Group enriched" "Detected in some" 4 "B-cells: 25.3;Plasma cells: 74.3;T-cells: 40.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 51.2;T-reg: 49.0" "Group enriched" "Detected in many" 16 "B-cells: 17.9;T-cells: 51.2" "Cancer enhanced" "Detected in some" "Leukemia: 14.5;lymphoma: 35.8" "Adipose subcutaneous - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" Receptor NA NA 350000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" 2 "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 60.2" "Group enriched" "Detected in some" 5 "B-cells: 21.7;Late spermatids: 22.9;NK-cells: 39.2;Plasma cells: 16.0;T-cells: 34.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 10.0;lymphoma: 35.7" "Breast - Plasma cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" 6 "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.5;lymphoid tissue: 60.3;stomach 1: 33.2" "Cell type enhanced" "Detected in some" "dendritic cells: 79.8;monocytes: 69.2;NK-cells: 63.0;Plasma cells: 252.7;Schwann cells: 65.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Myeloma: 188.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - T-cells, Lung - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 1200000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" Vesicles "CAB015445: AB_1121905, HPA055945: AB_2682980, HPA061654: AB_2684576" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.12e-3)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.08e-1)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-2)" SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 34.5;Kupffer cells: 19.9;Langerhans cells: 69.2;Macrophages: 39.8;Schwann cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Leukemia: 1.4;lymphoma: 2.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Fibroblasts, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" SLAMF9 "CD2F-10, CD84-H1, SF2001" ENSG00000162723 "SLAM family member 9" Q96A28 1 159951492-159954237 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Langerhans cells: 63.4;Late spermatids: 43.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 2.1" "Cancer enriched" "Detected in some" 7 "skin cancer: 8.1" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA035153 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Skin cancer - ECM organization" "Cluster 28: Dendritic cells - Antigen presentation" "HPA035153: AB_10670586" "unprognostic (1.05e-1)" "unprognostic (1.54e-5)" "unprognostic (6.12e-2)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (7.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" "unprognostic (2.46e-1)" "unprognostic (3.54e-4)" "unprognostic (5.27e-4)" "unprognostic (5.47e-2)" "unprognostic (6.17e-5)" "unprognostic (8.97e-3)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" SLC10A1 "NTCP, NTCP1" ENSG00000100652 "Solute carrier family 10 member 1" Q14973 14 69775416-69797241 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1050 "liver: 413.9" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 135.0" "Cancer enriched" "Detected in some" 79 "liver cancer: 65.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042727 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 76 "HPA042727: AB_10960691" "unprognostic (3.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.51e-2)" "unprognostic (2.11e-2)" "unprognostic (1.93e-2)" "unprognostic (6.51e-3)" "prognostic favorable (9.53e-6)" "unprognostic (6.07e-3)" "unprognostic (8.95e-2)" "unprognostic (2.17e-1)" "unprognostic (5.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.69e-2)" SLC10A2 "ASBT, IBAT, ISBT, NTCP2" ENSG00000125255 "Solute carrier family 10 member 2" Q12908 13 103043998-103066417 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 78.7" "Cell type enriched" "Detected in some" 20 "Proximal enterocytes: 348.0" "Cancer enriched" "Detected in single" 11 "renal cancer: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "ovarian cancer: 2.5" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004795 Approved NA NA "Cluster 25: Small intestine - Absorption" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 10 "HPA004795: AB_1856953" "unprognostic (2.82e-2)" "prognostic favorable (5.78e-5)" "unprognostic (1.64e-2)" "unprognostic (1.29e-1)" SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 69.5;Syncytiotrophoblasts: 109.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.9" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.9" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 18: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" SLC10A4 MGC29802 ENSG00000145248 "Solute carrier family 10 member 4" Q96EP9 4 48483343-48489526 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.8;pituitary gland: 6.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.7;Early spermatids: 3.5;Horizontal cells: 3.8;Inhibitory neurons: 15.4;Late spermatids: 4.9;Oligodendrocyte precursor cells: 3.8;Oocytes: 8.8" "Group enriched" "Detected in many" 4 "endometrial cancer: 1.8;glioma: 5.9" "Region enhanced" "Detected in many" "midbrain: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "Adrenocortical cancer: 23.7;Neuroblastoma: 50.9" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 22.4;midbrain: 88.3;pons: 36.8;spinal cord: 70.0" HPA028835 Uncertain Supported NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 4 "HPA028835: AB_10603025" "unprognostic (4.06e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (3.05e-3)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (5.41e-2)" "unprognostic (3.67e-1)" "unprognostic (1.86e-1)" "unprognostic (4.08e-3)" "unprognostic (9.98e-3)" "unprognostic (1.46e-1)" "unprognostic (3.50e-1)" "unprognostic (5.14e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (8.73e-2)" SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 11.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.3;Gastric mucus-secreting cells: 7.1;Hepatocytes: 3.0;Intestinal goblet cells: 3.8;Ionocytes: 2.6;Paneth cells: 2.8;Proximal enterocytes: 6.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 8.8;skin 1: 13.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 191.3" "Group enriched" "Detected in many" 5 "cervical cancer: 3.5;head and neck cancer: 6.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016662 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 124 "HPA016662: AB_1669899" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (8.31e-3)" "unprognostic (5.88e-2)" "unprognostic (8.87e-3)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.84e-4)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (9.22e-2)" "unprognostic (5.89e-4)" SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146522372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.1;Microglial cells: 48.3;Oligodendrocyte precursor cells: 58.5;Oligodendrocytes: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA039996: AB_10673266" "unprognostic (9.44e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (2.79e-1)" "unprognostic (6.69e-2)" "unprognostic (9.57e-2)" SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 35.3;lung: 76.2;lymphoid tissue: 45.5" "Group enriched" "Detected in many" 9 "Hofbauer cells: 171.8;Kupffer cells: 159.6;Macrophages: 216.8;monocytes: 503.9" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.4;non-classical monocyte: 6.1" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.4;monocytes: 6.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Liver - Neutrophils, Prostate - Macrophages, Skin - Macrophages, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 12: Non-specific - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" SLC11A2 "DCT1, DMT-1, DMT1, FLJ37416, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" Mitochondria "HPA032139: AB_10964213, HPA032140: AB_10962932" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.07e-6)" "unprognostic (1.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (2.29e-1)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" SLC12A1 "BSC, BSC-1, BSC1, CCC2, NKCC2" ENSG00000074803 "Solute carrier family 12 member 1" Q13621 15 48178438-48304078 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Bartter syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 825 "kidney: 687.0" "Group enriched" "Detected in some" 4 "Collecting duct cells: 33.1;Distal tubular cells: 92.2" "Cancer enriched" "Detected in single" 4 "renal cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014967, HPA018107" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Nucleoplasm "HPA014967: AB_1854503, HPA018107: AB_1854504" "unprognostic (3.52e-2)" "unprognostic (1.30e-2)" "unprognostic (9.65e-2)" "unprognostic (1.74e-2)" "unprognostic (7.77e-2)" "unprognostic (1.04e-1)" "unprognostic (8.72e-2)" "unprognostic (2.06e-1)" "unprognostic (9.85e-3)" "unprognostic (2.81e-4)" "unprognostic (9.75e-2)" "unprognostic (2.61e-1)" "unprognostic (5.47e-2)" "unprognostic (2.03e-1)" "unprognostic (5.20e-4)" "unprognostic (8.52e-2)" SLC12A2 "BSC-2, BSC2, CCC1, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Deafness, Disease variant, FDA approved drug targets, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 73.5" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 371.8;Oligodendrocytes: 527.4;Undifferentiated cells: 348.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "colorectal cancer: 106.3" "Adipose visceral - Endothelial cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Vesicles, Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" SLC12A3 "NCC, NCCT" ENSG00000070915 "Solute carrier family 12 member 3" P55017 16 56865207-56915850 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 118 "kidney: 98.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.8;dendritic cells: 20.8;Glandular and luminal cells: 4.2" "Cancer enhanced" "Detected in some" "renal cancer: 2.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 14.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 14.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 6.3;Uterine cancer: 6.7" "Kidney - Intercalated cells, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028748 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" "HPA028748: AB_10603886" "unprognostic (1.54e-3)" "unprognostic (7.09e-5)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "unprognostic (2.91e-1)" "unprognostic (2.38e-4)" "unprognostic (1.81e-1)" "unprognostic (9.70e-2)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (6.84e-2)" "unprognostic (1.83e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.38e-1)" "unprognostic (1.40e-2)" "unprognostic (1.70e-1)" SLC12A4 KCC1 ENSG00000124067 "Solute carrier family 12 member 4" Q9UP95 16 67943474-67969601 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.7;Syncytiotrophoblasts: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041138 Approved Approved Endosomes NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 8 Endosomes "HPA041138: AB_10794544" "unprognostic (5.07e-2)" "unprognostic (6.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (9.28e-2)" "unprognostic (1.48e-2)" "unprognostic (4.28e-2)" "unprognostic (3.26e-3)" "unprognostic (9.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.01e-2)" "unprognostic (1.81e-2)" "prognostic favorable (2.25e-6)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (7.64e-2)" "unprognostic (2.26e-1)" SLC12A5 "KCC2, KIAA1176" ENSG00000124140 "Solute carrier family 12 member 5" Q9H2X9 20 46021690-46060150 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 198.0;retina: 114.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 209.0;Cone photoreceptor cells: 249.8;Excitatory neurons: 89.7;Horizontal cells: 129.7;Inhibitory neurons: 87.4;Rod photoreceptor cells: 192.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072058 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA072058: AB_2686485" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" "unprognostic (9.44e-4)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.48e-1)" "unprognostic (5.16e-3)" "unprognostic (3.61e-1)" "unprognostic (2.49e-1)" "unprognostic (6.63e-2)" "unprognostic (3.72e-3)" "unprognostic (5.61e-4)" "unprognostic (8.78e-4)" "unprognostic (3.25e-2)" "unprognostic (9.22e-2)" "unprognostic (1.99e-1)" "unprognostic (2.34e-2)" SLC12A6 "ACCPN, KCC3, KCC3A, KCC3B" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 74: Neutrophils - Degranulation" 1 "Vesicles, Cytosol" "HPA034563: AB_10603887" "unprognostic (3.53e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (3.60e-1)" "unprognostic (3.55e-2)" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (2.88e-1)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.58e-2)" "unprognostic (1.83e-1)" "prognostic favorable (3.33e-6)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.41e-1)" SLC12A7 "DKFZP434F076, KCC4" ENSG00000113504 "Solute carrier family 12 member 7" Q9Y666 5 1050384-1112063 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 74.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041652 Approved Uncertain Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" Cytosol "HPA041652: AB_10793971" "unprognostic (2.22e-2)" "unprognostic (1.56e-1)" "unprognostic (8.92e-2)" "unprognostic (2.86e-1)" "unprognostic (1.69e-2)" "unprognostic (8.72e-2)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.67e-1)" "unprognostic (1.71e-3)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (3.44e-2)" "unprognostic (1.65e-3)" "unprognostic (1.17e-3)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "prognostic favorable (3.16e-5)" SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 22.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.3;Excitatory neurons: 37.1;Inhibitory neurons: 26.6;Intestinal goblet cells: 42.8;Oligodendrocyte precursor cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "HPA031123: AB_2301872" "unprognostic (4.74e-2)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (5.91e-3)" "unprognostic (7.35e-3)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.13e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (7.18e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-2)" SLC12A9 CIP1 ENSG00000146828 "Solute carrier family 12 member 9" Q9BXP2 7 100826820-100867010 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067536 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Lung - Lung function" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA067536: AB_2732768" "unprognostic (6.53e-2)" "unprognostic (3.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.11e-3)" "unprognostic (3.47e-2)" "unprognostic (2.37e-2)" "unprognostic (8.38e-3)" "prognostic favorable (5.97e-4)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.00e-4)" "unprognostic (2.47e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.52e-2)" "unprognostic (6.00e-2)" "unprognostic (6.74e-3)" "unprognostic (6.38e-2)" SLC13A1 "NAS1, NaSi-1" ENSG00000081800 "Solute carrier family 13 member 1" Q9BZW2 7 123113531-123199972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sulfate transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 79.0" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 427.8" "Cancer enriched" "Detected in single" 219 "renal cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA053615, HPA062714" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA053615: AB_2682207, HPA062714: AB_2684846" "unprognostic (1.86e-1)" "prognostic favorable (8.95e-5)" "unprognostic (1.71e-1)" "unprognostic (3.76e-1)" SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 125.7;kidney: 41.5;salivary gland: 46.8" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 262.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "choroid plexus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014963 Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 3 "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 392.3" "Cell type enhanced" "Detected in many" "Astrocytes: 51.1;Cytotrophoblasts: 105.3;Excitatory neurons: 62.8;Oligodendrocytes: 165.8;Proximal tubular cells: 183.6;Syncytiotrophoblasts: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Proximal tubular cells - Transmembrane transport" 9 "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" SLC13A4 "SUT-1, SUT1" ENSG00000164707 "Solute carrier family 13 member 4" Q9UKG4 7 135681231-135729258 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "choroid plexus: 1503.1" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 760.4" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Region enriched" "Detected in all" 20 "choroid plexus: 1925.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.9;testis cancer: 3.1" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048582 Enhanced NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 22 "HPA048582: AB_2680450" "unprognostic (2.40e-1)" "unprognostic (2.51e-1)" "unprognostic (9.70e-3)" "unprognostic (1.78e-1)" "unprognostic (7.69e-2)" "unprognostic (3.96e-6)" "unprognostic (3.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.56e-3)" "unprognostic (9.23e-2)" "unprognostic (2.89e-1)" "unprognostic (1.87e-1)" "unprognostic (2.30e-6)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (2.00e-1)" "unprognostic (6.73e-2)" SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 403.8" "Group enriched" "Detected in some" 10 "Hepatocytes: 300.5;Kupffer cells: 95.4;Serous glandular cells: 330.9" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bile duct cancer: 2.9;liver cancer: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 83: Liver - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 75: Serous glandular cells - Salivary secretion" 16 "Nucleoplasm, Plasma membrane" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.2;prostate: 75.7;urinary bladder: 87.4" "Group enriched" "Detected in many" 4 "Adipocytes: 93.3;Astrocytes: 216.7" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 35.3;thyroid cancer: 34.9" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" SLC15A1 "HPECT1, HPEPT1, PEPT1" ENSG00000088386 "Solute carrier family 15 member 1" P46059 13 98683801-98752672 "Metabolic proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 197.2" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 352.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.4;pancreatic cancer: 11.1" "Colon - Colon enterocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002827 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Small intestine - Absorption" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Cytosol" "HPA002827: AB_1856974" "unprognostic (8.76e-2)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (6.26e-2)" "unprognostic (7.83e-2)" "unprognostic (5.47e-2)" "unprognostic (1.92e-1)" "unprognostic (2.37e-1)" "unprognostic (6.79e-2)" "unprognostic (6.88e-4)" "unprognostic (2.11e-2)" "unprognostic (2.84e-1)" "unprognostic (2.64e-1)" "unprognostic (9.01e-2)" "unprognostic (3.87e-2)" SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 93.6;Kupffer cells: 60.0;Langerhans cells: 54.7;Macrophages: 85.6;monocytes: 134.2;Muller glia cells: 197.9;Schwann cells: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" 5 Vesicles "HPA047880: AB_10959455, HPA057642: AB_2683487" "unprognostic (5.61e-2)" "prognostic favorable (4.07e-5)" "unprognostic (8.79e-2)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (9.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" SLC15A4 "PHT1, PTR4" ENSG00000139370 "Solute carrier family 15 member 4" Q8N697 12 128793194-128823958 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 420.1;Early spermatids: 97.4;Late spermatids: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 31.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016713 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" 1 "HPA016713: AB_1856978" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (3.63e-2)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.45e-4)" "prognostic unfavorable (6.78e-4)" "unprognostic (5.14e-3)" "unprognostic (6.39e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-1)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.56e-6)" "unprognostic (1.28e-1)" "unprognostic (2.06e-1)" "unprognostic (2.34e-2)" "unprognostic (2.57e-1)" SLC15A5 ENSG00000188991 "Solute carrier family 15 member 5" A6NIM6 12 16188485-16277685 "Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Cone photoreceptor cells: 1.7;Early spermatids: 5.4;Excitatory neurons: 1.1;Late spermatids: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041638 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA041638: AB_2677590" "unprognostic (3.68e-3)" "unprognostic (1.64e-1)" "unprognostic (4.89e-6)" "unprognostic (1.34e-1)" "unprognostic (1.72e-3)" SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 149.2;Cone photoreceptor cells: 151.2;Late spermatids: 136.1;Muller glia cells: 167.1;Rod photoreceptor cells: 332.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: AB_2686337" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavorable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.8;skeletal muscle: 39.6" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 45.8;Macrophages: 39.5;Melanocytes: 67.0;monocytes: 63.7;Skeletal myocytes: 88.8" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Region enhanced" "Detected in all" "choroid plexus: 86.5" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Stomach - Chief cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Monocytes - Innate immune response" 3 "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" SLC16A13 MCT13 ENSG00000174327 "Solute carrier family 16 member 13" Q7RTY0 17 7036015-7040117 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.2" "Cell type enhanced" "Detected in many" "B-cells: 5.1;Basal squamous epithelial cells: 5.8;Collecting duct cells: 5.8;Hepatocytes: 6.5;Squamous epithelial cells: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065245 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 16 "Golgi apparatus" Cytosol "HPA065245: AB_2685443" "unprognostic (5.61e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (1.78e-1)" "unprognostic (2.22e-3)" "unprognostic (9.53e-2)" "unprognostic (1.62e-1)" "unprognostic (8.72e-2)" "unprognostic (1.81e-1)" "unprognostic (2.60e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.44e-2)" "unprognostic (7.31e-3)" "unprognostic (9.70e-3)" "unprognostic (3.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.14e-1)" SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Adipocytes: 16.2;Excitatory neurons: 17.9;Inhibitory neurons: 20.2;Microglial cells: 42.9;Oligodendrocyte precursor cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 21.7" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 22: Eosinophils - Transcription" "Cluster 80: Non-specific - Endocytosis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" SLC16A2 "AHDS, DXS128, DXS128E, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 39.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.1;Hepatocytes: 52.5;Inhibitory neurons: 20.6;Oligodendrocyte precursor cells: 21.7;Peritubular cells: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 66.9" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 191.2" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 1954.4;Syncytiotrophoblasts: 690.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 110.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 119.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 56.4;Extravillous trophoblasts: 39.1;Proximal tubular cells: 154.6" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 31.1" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 18: Non-specific - Translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 44.1;epididymis: 32.0;retina: 29.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.7;Glandular and luminal cells: 30.2;Kupffer cells: 23.6;Macrophages: 29.9;monocytes: 39.9;Rod photoreceptor cells: 44.1;Suprabasal keratinocytes: 21.1" "Group enriched" "Detected in many" 6 "breast cancer: 10.9;melanoma: 11.3" "Region enriched" "Detected in all" 7 "choroid plexus: 108.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "skin cancer: 114.0" "Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 1 Vesicles "HPA054459: AB_2682494, HPA066328: AB_2685660" "unprognostic (2.53e-2)" "unprognostic (2.09e-3)" "unprognostic (8.41e-2)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.26e-3)" "unprognostic (5.08e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-2)" "unprognostic (8.78e-2)" "unprognostic (2.23e-1)" "unprognostic (8.16e-3)" "unprognostic (2.09e-2)" "unprognostic (9.46e-2)" SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 33.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 175.9;Early spermatids: 124.5;Excitatory neurons: 145.5;Inhibitory neurons: 123.0;Late spermatids: 137.3" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 30.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 30: Heart muscle - Heart development" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084184 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8" "Cell type enhanced" "Detected in some" "Muller glia cells: 4.2;Oocytes: 15.4;Skeletal myocytes: 4.9;Spermatogonia: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.7" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 146.8;kidney: 184.4" "Cell type enhanced" "Detected in many" "Astrocytes: 79.6;Distal enterocytes: 54.7;Ovarian stromal cells: 47.7;Proximal tubular cells: 176.2" "Cancer enhanced" "Detected in many" "renal cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 38: Proximal tubular cells - Transmembrane transport" 3 Nucleoplasm "Cell Junctions" "HPA049286: AB_2680699" "unprognostic (3.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-3)" "unprognostic (1.76e-2)" "unprognostic (5.96e-2)" "unprognostic (3.50e-3)" "unprognostic (5.01e-2)" "unprognostic (2.11e-3)" "unprognostic (5.99e-2)" "unprognostic (4.60e-2)" "prognostic favorable (2.56e-6)" "unprognostic (7.57e-3)" "unprognostic (1.27e-2)" "unprognostic (3.72e-1)" "unprognostic (1.94e-1)" SLC17A1 "NAPI-1, NPT1" ENSG00000124568 "Solute carrier family 17 member 1" Q14916 6 25782915-25832052 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 49 "kidney: 163.0;liver: 47.9" "Cell type enhanced" "Detected in some" "Early spermatids: 12.5;Hepatocytes: 8.7;Proximal tubular cells: 42.1" "Group enriched" "Detected in some" 150 "liver cancer: 7.6;renal cancer: 19.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney cancer: 12.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050513 Uncertain "Golgi apparatus" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "HPA050513: AB_2681152" "unprognostic (6.98e-2)" "unprognostic (2.99e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-3)" "unprognostic (1.32e-1)" "unprognostic (2.37e-1)" "unprognostic (4.74e-1)" SLC17A2 NPT3 ENSG00000112337 "Solute carrier family 17 member 2" O00624 6 25912754-25930691 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 166 "liver: 77.1" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 27.0" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038270 Uncertain NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA038270: AB_10672511" "prognostic favorable (8.54e-4)" "unprognostic (1.90e-2)" "unprognostic (4.14e-2)" SLC17A4 KIAA2138 ENSG00000146039 "Solute carrier family 17 member 4" Q9Y2C5 6 25754699-25781199 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "gallbladder: 15.7;intestine: 31.0;liver: 46.2;pancreas: 22.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 82.0;Distal enterocytes: 84.8;Hepatocytes: 33.9;Intestinal goblet cells: 19.7;Paneth cells: 36.5;Proximal enterocytes: 43.2" "Group enriched" "Detected in some" 6 "liver cancer: 11.0;renal cancer: 7.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 3.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 1.8" HPA055564 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA055564: AB_2682852" "unprognostic (6.52e-2)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 300.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" SLC17A6 "DNPI, VGLUT2" ENSG00000091664 "Solute carrier family 17 member 6" Q9P2U8 11 22338381-22379503 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;pituitary gland: 3.5;retina: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 14.0;Horizontal cells: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6;skin cancer: 1.1" "Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "basal ganglia: 51.9;hypothalamus: 139.9;midbrain: 172.4;pons and medulla: 86.5;thalamus: 165.0" "Low region specificity" "Detected in all" "CAB037130, HPA039226, CAB078204" Supported Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "CAB037130: AB_477611, CAB078204: AB_2665794, HPA039226: AB_2676400" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 32 "brain: 396.8;retina: 306.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 353.0;Cone photoreceptor cells: 482.6;Excitatory neurons: 104.2;Rod photoreceptor cells: 390.0" "Cancer enriched" "Detected in some" 6 "glioma: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 15.9" "Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 265.6;cerebellum: 272.5;cerebral cortex: 444.1;hippocampal formation: 614.7" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "CAB037183: AB_261840, HPA050458: AB_2681134, HPA063679: AB_2685086" "unprognostic (1.79e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (9.12e-2)" "unprognostic (3.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.32e-2)" "unprognostic (6.61e-2)" "unprognostic (4.26e-12)" "unprognostic (8.36e-4)" "unprognostic (4.27e-1)" "unprognostic (1.35e-2)" "unprognostic (6.17e-3)" SLC17A8 "DFNA25, VGLUT3" ENSG00000179520 "Solute carrier family 17 member 8" Q8NDX2 12 100357074-100422055 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.0;lymphoid tissue: 1.3" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 34.0" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 5 "cerebral cortex: 24.1;midbrain: 18.5;pons: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038870, CAB079058" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "Endoplasmic reticulum" "CAB079058: , HPA038870: " "unprognostic (4.52e-3)" "unprognostic (2.18e-1)" "unprognostic (8.56e-2)" "unprognostic (1.32e-3)" "unprognostic (3.65e-1)" "unprognostic (7.67e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-2)" "unprognostic (8.89e-2)" "unprognostic (3.55e-1)" SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 23.6;Hepatocytes: 32.3;Hofbauer cells: 16.2;Langerhans cells: 14.5;Plasma cells: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 29.4" "Breast - Plasma cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA047470 Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 77: Plasma cells - Protein processing" 6 Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" SLC18A1 "CGAT, VAT1, VMAT1" ENSG00000036565 "Solute carrier family 18 member A1" P54219 8 20144855-20183206 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "adrenal gland: 24.3" "Cell type enriched" "Detected in some" 55 "Enteroendocrine cells: 99.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.8" "Region enriched" "Detected in single" 20 "midbrain: 8.5" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 19 "monocytes: 2.8" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 35.1" "Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA006877, HPA063797" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA006877: AB_2667690, HPA063797: AB_2685125" "unprognostic (8.03e-4)" "unprognostic (1.02e-1)" "unprognostic (3.75e-3)" "unprognostic (3.50e-1)" "unprognostic (6.61e-2)" "unprognostic (3.09e-3)" "unprognostic (1.67e-1)" "unprognostic (2.16e-2)" "unprognostic (3.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-2)" "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.8;cervix: 28.9" "Group enriched" "Detected in many" 18 "Glandular and luminal cells: 120.8;granulocytes: 464.4" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 12 "hypothalamus: 47.5;midbrain: 173.0;pons: 150.4" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Group enriched" "Detected in some" 5 "Leukemia: 9.7;Neuroblastoma: 7.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Skin - Langerhans cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "midbrain: 62.8" "Region enriched" "Detected in all" 4 "midbrain: 145.2" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 8 "Vesicles, Centrosome" "HPA073224: AB_2732222" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (9.00e-2)" "unprognostic (2.85e-1)" "unprognostic (5.33e-3)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.06e-3)" "unprognostic (7.94e-5)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" SLC18A3 VACHT ENSG00000187714 "Solute carrier family 18 member A3" Q16572 10 49610310-49612720 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 5.3" "Cell type enriched" "Detected in single" 4 "Smooth muscle cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.4;Neuroblastoma: 14.7" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 102.5" CAB079011 Supported NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" 1 "CAB079011: " "unprognostic (2.14e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (9.39e-2)" "unprognostic (4.55e-2)" "unprognostic (3.00e-1)" "unprognostic (5.85e-3)" "unprognostic (7.56e-2)" "unprognostic (1.16e-1)" SLC18B1 "C6orf192, dJ55C23.6" ENSG00000146409 "Solute carrier family 18 member B1" Q6NT16 6 132769370-132813339 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029747 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" Cytosol "HPA029747: AB_10600797" "unprognostic (1.84e-2)" "unprognostic (3.94e-1)" "unprognostic (4.22e-2)" "unprognostic (2.85e-1)" "unprognostic (2.41e-2)" "prognostic favorable (3.55e-4)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.53e-1)" "unprognostic (2.39e-1)" "unprognostic (4.09e-1)" "unprognostic (6.97e-3)" "unprognostic (1.13e-1)" "prognostic favorable (9.24e-4)" "unprognostic (7.20e-3)" "unprognostic (1.08e-1)" "unprognostic (2.08e-2)" "unprognostic (7.88e-2)" SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.1" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 151.7;Syncytiotrophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 188.5" "Immune cell enriched" "Detected in many" 4 "neutrophil: 103.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane" "HPA024802: AB_10602892" "unprognostic (4.31e-3)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.23e-2)" "unprognostic (2.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "unprognostic (2.87e-3)" "unprognostic (4.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.07e-10)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (7.97e-5)" "unprognostic (3.10e-1)" SLC19A2 "ThT1, THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 119.8;tongue: 81.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 106.4;Syncytiotrophoblasts: 199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Fibroblasts - ECM organization" 1 Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 44.8;breast: 27.5;placenta: 23.3" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 66.3;Syncytiotrophoblasts: 166.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 10.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 9 Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" SLC1A1 "EAAC1, EAAT3, hEAAC1" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 43.9;intestine: 62.9;kidney: 49.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.3;Excitatory neurons: 46.8;Glandular and luminal cells: 120.6;Hepatocytes: 57.7;Inhibitory neurons: 47.9;Microglial cells: 64.4;Oligodendrocyte precursor cells: 151.4;Proximal enterocytes: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" SLC1A2 "EAAT2, GLT-1, GLT1, HBGT" ENSG00000110436 "Solute carrier family 1 member 2" P43004 11 35251205-35420063 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 450.6" "Cell type enriched" "Detected in many" 7 "Astrocytes: 4369.6" "Cancer enriched" "Detected in some" 5 "glioma: 28.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.4;Neuroblastoma: 4.0" "Breast - Breast glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002574, HPA009172, HPA067499" Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Astrocytes - Unknown function" 1 "CAB002574: AB_564087, HPA009172: AB_1849764, HPA067499: " "unprognostic (8.00e-2)" "unprognostic (5.71e-3)" "unprognostic (1.39e-1)" "unprognostic (2.77e-2)" "unprognostic (1.33e-1)" "unprognostic (5.65e-3)" "unprognostic (1.39e-2)" "unprognostic (9.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.65e-2)" "unprognostic (1.79e-3)" "unprognostic (2.35e-1)" "unprognostic (8.33e-4)" "unprognostic (6.34e-2)" "unprognostic (8.06e-2)" "unprognostic (5.24e-2)" "unprognostic (3.49e-2)" SLC1A3 "EA6, EAAT1, GLAST, GLAST-1, GLAST1" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 438.7;retina: 214.2" "Cell type enhanced" "Detected in many" "Astrocytes: 1645.7;Microglial cells: 317.6;Muller glia cells: 511.0;Oligodendrocyte precursor cells: 223.1;Oligodendrocytes: 231.8" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" 3 "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" SLC1A4 "ASCT-1, ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Astrocytes: 66.3;dendritic cells: 85.7;Melanocytes: 151.2;Plasma cells: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 90.8;skin cancer: 116.0" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Enhanced Enhanced Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 96.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 80: Non-specific - Transcription" 1 "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950033-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 117.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.1;Early spermatids: 32.7;Extravillous trophoblasts: 12.3;Horizontal cells: 10.7;Late spermatids: 36.2;Syncytiotrophoblasts: 44.1" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 5 "cerebellum: 159.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.1;breast cancer: 8.4" "Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 70.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 39.0" "Group enriched" "Detected in some" 6 "Bipolar cells: 184.0;Cone photoreceptor cells: 79.9;Rod photoreceptor cells: 68.9" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cancer enhanced" "Detected in some" "Brain cancer: 4.1;breast cancer: 5.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049124 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" SLC20A1 "Glvr-1, GLVR1, PiT-1, PiT1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 210.3;Distal enterocytes: 312.5;monocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834, HPA064386" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB019279: , HPA035834: AB_2674809, HPA064386: " "unprognostic (1.81e-1)" "unprognostic (2.18e-1)" "unprognostic (5.38e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.50e-2)" "unprognostic (3.38e-2)" "unprognostic (2.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.43e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.44e-5)" "unprognostic (6.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-3)" SLC20A2 "Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1" ENSG00000168575 "Solute carrier family 20 member 2" Q08357 8 42416475-42541926 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Phosphate transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 150.4;skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026540 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" "HPA026540: AB_1855408" "prognostic unfavorable (7.67e-4)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.27e-2)" "unprognostic (2.12e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.95e-1)" "unprognostic (7.62e-2)" "unprognostic (2.06e-1)" "unprognostic (3.43e-2)" "prognostic favorable (1.01e-4)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (5.86e-2)" "unprognostic (4.95e-2)" SLC22A1 OCT1 ENSG00000175003 "Solute carrier family 22 member 1" O15245 6 160121815-160158718 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 381 "liver: 594.8" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 803.2" "Cancer enriched" "Detected in some" 81 "liver cancer: 83.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA029846 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Plasma proteins" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Hepatocytes - Metabolism" 2 "HPA029846: AB_10603026" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "unprognostic (7.80e-2)" "unprognostic (2.68e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-2)" "prognostic favorable (1.35e-5)" "unprognostic (2.28e-1)" "unprognostic (8.61e-2)" "unprognostic (3.35e-1)" "unprognostic (9.11e-2)" "unprognostic (9.94e-2)" "unprognostic (1.46e-7)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (4.72e-2)" "unprognostic (8.07e-4)" SLC22A11 OAT4 ENSG00000168065 "Solute carrier family 22 member 11" Q9NSA0 11 64555690-64572875 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 71 "epididymis: 10.3;kidney: 30.8;placenta: 32.3" "Group enriched" "Detected in some" 33 "Cytotrophoblasts: 628.4;Syncytiotrophoblasts: 1718.7" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA026076 Enhanced NA NA "Cluster 57: Lung - Lung function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA026076: AB_1854756" "unprognostic (8.21e-5)" "unprognostic (3.29e-2)" "unprognostic (3.57e-1)" "unprognostic (1.57e-1)" "unprognostic (3.20e-2)" "unprognostic (4.57e-3)" "unprognostic (3.48e-1)" "unprognostic (1.93e-1)" "unprognostic (4.86e-2)" "unprognostic (4.51e-2)" "unprognostic (7.56e-2)" "unprognostic (1.13e-1)" "prognostic favorable (3.68e-5)" "unprognostic (4.62e-2)" "unprognostic (6.52e-2)" "unprognostic (3.50e-2)" "unprognostic (8.24e-3)" SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 205 "kidney: 106.4" "Cell type enriched" "Detected in some" 20 "Proximal tubular cells: 128.6" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" SLC22A13 "OAT10, OCTL1, OCTL3, ORCTL3" ENSG00000172940 "Solute carrier family 22 member 13" Q9Y226 3 38265812-38278757 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "kidney: 8.7" "Cell type enhanced" "Detected in some" "Horizontal cells: 4.4;Ionocytes: 2.9;Proximal tubular cells: 6.6;Sertoli cells: 2.7" "Cancer enriched" "Detected in single" 7 "renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035603, HPA035962" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA035603: AB_10672869, HPA035962: AB_2674890" "unprognostic (2.73e-2)" "unprognostic (6.70e-2)" "unprognostic (2.80e-1)" "unprognostic (5.68e-2)" "unprognostic (7.13e-3)" "unprognostic (3.50e-3)" "unprognostic (6.83e-2)" "unprognostic (1.49e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-5)" "unprognostic (3.39e-1)" "unprognostic (1.96e-2)" "unprognostic (5.24e-2)" "unprognostic (2.74e-1)" SLC22A15 FLIPT1 ENSG00000163393 "Solute carrier family 22 member 15" Q8IZD6 1 115976513-116070054 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 232.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 8 "granulocytes: 1.3;monocytes: 1.2" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019785 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" "HPA019785: AB_1857011" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "unprognostic (5.22e-2)" "unprognostic (5.85e-5)" "unprognostic (8.91e-3)" "unprognostic (1.81e-1)" "unprognostic (4.97e-2)" "unprognostic (5.15e-2)" "unprognostic (9.06e-2)" "unprognostic (7.29e-3)" "unprognostic (8.78e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-4)" "unprognostic (1.30e-1)" SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 20.2;testis: 20.8" "Group enriched" "Detected in some" 20 "Early spermatids: 39.6;Erythroid cells: 49.8;Late spermatids: 30.6;Spermatocytes: 34.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.8;classical monocyte: 7.0" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.8;monocytes: 7.0" "Cancer enriched" "Detected in single" 11 "Leukemia: 10.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Erythroid cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 4: Testis - Basic cellular processes" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" SLC22A17 "BOCT, BOIT, NGALR" ENSG00000092096 "Solute carrier family 22 member 17" Q8WUG5 14 23346314-23352912 "Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 331.6;choroid plexus: 241.7;pituitary gland: 208.5" "Cell type enhanced" "Detected in many" "Horizontal cells: 137.2;Inhibitory neurons: 106.2;Oligodendrocyte precursor cells: 113.2;Prostatic glandular cells: 141.8" "Cancer enhanced" "Detected in all" "glioma: 51.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.2" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002728 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" 1 "HPA002728: AB_1079998" "unprognostic (9.34e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.23e-3)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.31e-2)" "unprognostic (1.26e-2)" "unprognostic (4.23e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.73e-4)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (3.50e-2)" "unprognostic (1.23e-2)" "unprognostic (3.87e-2)" SLC22A18 "BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5" ENSG00000110628 "Solute carrier family 22 member 18" Q96BI1 11 2899721-2925246 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.9;liver: 44.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 390.5;Late spermatids: 503.2;Paneth cells: 258.5;Proximal enterocytes: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA067812, HPA071461" Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 "HPA067812: AB_2685902, HPA071461: AB_2686401" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (4.80e-1)" "unprognostic (7.75e-2)" "unprognostic (7.92e-3)" "unprognostic (2.67e-1)" "unprognostic (8.25e-2)" "unprognostic (4.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.48e-2)" "unprognostic (9.35e-2)" "unprognostic (8.60e-2)" "unprognostic (8.36e-2)" "unprognostic (9.51e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-1)" "unprognostic (2.82e-1)" SLC22A2 OCT2 ENSG00000112499 "Solute carrier family 22 member 2" O15244 6 160171061-160277638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 80 "kidney: 148.4" "Group enriched" "Detected in some" 7 "Distal tubular cells: 55.3;Proximal tubular cells: 143.4" "Cancer enriched" "Detected in single" 493 "renal cancer: 30.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.4;prostate cancer: 1.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 2.5" "HPA008549, CAB068236, CAB068237" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "CAB068236: AB_2665668, CAB068237: AB_2665669, HPA008549: " "unprognostic (1.01e-1)" "unprognostic (3.67e-1)" "unprognostic (2.26e-1)" "unprognostic (3.67e-2)" "unprognostic (4.24e-1)" "unprognostic (3.33e-1)" "unprognostic (2.51e-2)" "unprognostic (3.30e-1)" "unprognostic (1.42e-2)" "unprognostic (1.15e-4)" "unprognostic (1.41e-1)" "unprognostic (3.68e-1)" "prognostic favorable (1.85e-7)" "unprognostic (1.65e-2)" "unprognostic (8.20e-2)" "unprognostic (4.11e-1)" "unprognostic (2.45e-2)" SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 233.7;Oligodendrocytes: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 3 "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" SLC22A24 "MGC34821, NET46" ENSG00000197658 "Solute carrier family 22 member 24" Q8N4F4 11 63079940-63144221 "Predicted membrane proteins" "Ion transport, Lipid metabolism, Lipid transport, Steroid metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "kidney: 4.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 5.7;Proximal tubular cells: 10.8" "Cancer enriched" "Detected in single" 11 "renal cancer: 0.5" "Region enhanced" "Detected in many" "cerebral cortex: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA045015 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA045015: AB_2679183" "unprognostic (5.72e-3)" "unprognostic (1.80e-7)" SLC22A25 "HIMTP, MGC120420, UST6" ENSG00000196600 "Solute carrier family 22 member 25" Q6T423 11 63158437-63243599 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "liver: 15.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.3;Hepatocytes: 4.9;Inhibitory neurons: 1.1;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.1" "Cancer enriched" "Detected in single" 66 "liver cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes" HPA039390 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 50: Lymphoma - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "HPA039390: AB_10671996" "unprognostic (3.19e-2)" "unprognostic (2.38e-1)" "unprognostic (4.51e-1)" "prognostic favorable (7.04e-4)" "unprognostic (1.01e-1)" SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 65.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.9;Hepatocytes: 53.6;Inhibitory neurons: 23.8;Leydig cells: 36.5;Peritubular cells: 25.5;Prostatic glandular cells: 80.3" "Cancer enhanced" "Detected in many" "prostate cancer: 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.8;prostate cancer: 30.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 69: Neurons - Neuronal signaling" Vesicles Cytosol "HPA029750: AB_10603888" "unprognostic (8.61e-2)" "prognostic unfavorable (7.19e-5)" "unprognostic (4.14e-1)" "unprognostic (1.49e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (3.36e-2)" "unprognostic (9.74e-2)" "unprognostic (9.36e-4)" "unprognostic (1.33e-2)" "unprognostic (2.58e-2)" "unprognostic (7.28e-2)" "unprognostic (7.96e-2)" "unprognostic (5.21e-2)" "unprognostic (8.13e-4)" "prognostic unfavorable (7.26e-4)" SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.4" "Group enriched" "Detected in many" 4 "Ciliated cells: 50.9;Erythroid cells: 34.6;Proximal enterocytes: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in many" "CAB015468, HPA036974" Approved Approved Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 42: Ciliated cells - Cilium assembly" Mitochondria "CAB015468: , HPA036974: AB_2732474" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (8.42e-3)" "unprognostic (6.17e-2)" "unprognostic (6.22e-3)" "unprognostic (4.17e-3)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.82e-2)" "unprognostic (1.74e-2)" "unprognostic (2.31e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" "unprognostic (4.06e-2)" SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.9;Proximal enterocytes: 44.8" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063062 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" SLC22A6 "OAT1, PAHT, ROAT1" ENSG00000197901 "Solute carrier family 22 member 6" Q4U2R8 11 62936385-62984967 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "kidney: 189.5" "Cell type enriched" "Detected in some" 36 "Proximal tubular cells: 170.6" "Cancer enriched" "Detected in single" 102 "renal cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074559, CAB075704" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "CAB075704: , HPA074559: AB_2732260" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (4.43e-1)" SLC22A7 "NLT, OAT2" ENSG00000137204 "Solute carrier family 22 member 7" Q9Y694 6 43295694-43305538 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 417.7" "Group enriched" "Detected in some" 11 "Hepatocytes: 186.3;Proximal tubular cells: 52.6" "Cancer enriched" "Detected in some" 37 "liver cancer: 81.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA030220 Approved NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA030220: AB_10603027" "unprognostic (9.17e-2)" "unprognostic (9.73e-4)" "unprognostic (2.13e-1)" "prognostic favorable (5.48e-6)" "unprognostic (1.45e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" SLC22A8 OAT3 ENSG00000149452 "Solute carrier family 22 member 8" Q8TCC7 11 62989154-63015841 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Detoxification, Ion transport, Lipid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 203 "choroid plexus: 273.8;kidney: 322.8" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 170.1" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Region enriched" "Detected in some" 31 "choroid plexus: 242.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044174 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA044174: AB_10963058" "unprognostic (5.35e-4)" "unprognostic (4.66e-1)" "unprognostic (6.88e-3)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" SLC23A1 "SLC23A2, SVCT1, YSPL3" ENSG00000170482 "Solute carrier family 23 member 1" Q9UHI7 5 139367196-139384553 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "fallopian tube: 52.4;intestine: 63.5;kidney: 38.7;liver: 21.9" "Group enriched" "Detected in some" 4 "Ciliated cells: 32.8;Proximal enterocytes: 128.7" "Group enriched" "Detected in many" 5 "endometrial cancer: 2.1;liver cancer: 7.7;prostate cancer: 4.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Leukemia: 9.2;lymphoma: 10.5;Myeloma: 20.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047612 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Proximal enterocytes - Digestion" 10 "HPA047612: AB_2680102" "unprognostic (4.00e-3)" "unprognostic (2.66e-3)" "unprognostic (2.63e-2)" "unprognostic (1.75e-3)" "unprognostic (1.93e-1)" "unprognostic (6.36e-6)" "unprognostic (7.41e-2)" "unprognostic (6.55e-2)" "unprognostic (5.88e-2)" "unprognostic (3.90e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (4.16e-2)" "unprognostic (1.55e-2)" "unprognostic (3.65e-3)" SLC23A2 "KIAA0238, SLC23A1, SVCT2, YSPL2" ENSG00000089057 "Solute carrier family 23 member 2" Q9UGH3 20 4852356-5010293 "Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 96.2;retina: 104.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 200.8;Excitatory neurons: 99.2;Inhibitory neurons: 112.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052825, HPA059314" Approved Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Neuronal - Synaptic function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 25: Bipolar cells - Visual perception" Vesicles "Golgi apparatus" "HPA052825: AB_2681965, HPA059314: AB_2683975" "unprognostic (3.83e-1)" "unprognostic (1.08e-2)" "unprognostic (1.95e-3)" "unprognostic (1.64e-3)" "unprognostic (8.05e-2)" "unprognostic (2.09e-1)" "prognostic favorable (3.35e-4)" "unprognostic (6.22e-3)" "unprognostic (2.08e-1)" "unprognostic (6.36e-3)" "prognostic favorable (7.14e-5)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.08e-5)" SLC23A3 "FLJ31168, SVCT3, Yspl1" ENSG00000213901 "Solute carrier family 23 member 3" Q6PIS1 2 219161465-219170095 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 17.9;kidney: 43.9" "Group enriched" "Detected in many" 4 "Proximal enterocytes: 50.3;Proximal tubular cells: 12.7" "Cancer enriched" "Detected in some" 9 "renal cancer: 5.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected" "Not detected" HPA019059 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA019059: AB_1857017" "unprognostic (2.49e-2)" "unprognostic (6.65e-2)" "unprognostic (2.05e-4)" "unprognostic (6.97e-2)" "unprognostic (8.41e-2)" "unprognostic (1.22e-2)" "unprognostic (9.07e-2)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (4.35e-2)" "unprognostic (3.10e-1)" "unprognostic (6.12e-4)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (2.41e-2)" "unprognostic (3.34e-1)" "unprognostic (6.52e-5)" SLC24A1 "CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX" ENSG00000074621 "Solute carrier family 24 member 1" O60721 15 65611366-65660995 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Symport, Transport, Vision" "Congenital stationary night blindness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 35 "retina: 187.5" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 178.7;Rod photoreceptor cells: 296.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039370 Enhanced Approved Microtubules NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" Microtubules "HPA039370: AB_10960279" "unprognostic (9.47e-2)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.66e-3)" "unprognostic (6.39e-3)" "unprognostic (4.64e-1)" "unprognostic (8.82e-2)" "unprognostic (1.86e-1)" "unprognostic (4.69e-2)" "unprognostic (3.94e-1)" "unprognostic (2.01e-1)" "unprognostic (9.91e-2)" "prognostic favorable (2.33e-6)" "unprognostic (8.45e-2)" "unprognostic (9.22e-2)" "unprognostic (3.04e-2)" "unprognostic (1.96e-2)" SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19789037 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 26.4;retina: 15.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 266.8;Excitatory neurons: 645.5;Inhibitory neurons: 612.6;Oligodendrocytes: 2521.9" "Group enriched" "Detected in some" 4 "breast cancer: 0.5;glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA079359: " "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.48e-2)" "unprognostic (8.46e-2)" "unprognostic (8.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-2)" "unprognostic (6.51e-2)" "unprognostic (1.57e-2)" "unprognostic (2.08e-4)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (1.51e-2)" SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 127.6;Inhibitory neurons: 310.7;Oligodendrocyte precursor cells: 352.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "basophil: 5.7;eosinophil: 1.9" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.7" "Group enriched" "Detected in some" 4 "Bile duct cancer: 6.2;Bone cancer: 13.7;breast cancer: 11.4" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" SLC24A4 NCKX4 ENSG00000140090 "Solute carrier family 24 member 4" Q8NFF2 14 92322581-92501481 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 44.8;retina: 12.0" "Cell type enhanced" "Detected in some" "Astrocytes: 44.6;Bipolar cells: 231.5;Cone photoreceptor cells: 113.8;monocytes: 94.7;Schwann cells: 42.2" "Group enriched" "Detected in some" 5 "glioma: 0.5;melanoma: 0.8" "Region enhanced" "Detected in all" "choroid plexus: 200.5" "Group enriched" "Detected in some" 4 "classical monocyte: 11.1;intermediate monocyte: 14.7;non-classical monocyte: 11.6" "Lineage enriched" "Detected in many" 5 "monocytes: 14.7" "Group enriched" "Detected in some" 10 "Sarcoma: 4.4;skin cancer: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063206 Approved "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 25: Bipolar cells - Visual perception" "Plasma membrane" "HPA063206: " "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (3.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-3)" "unprognostic (3.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (3.21e-1)" "unprognostic (1.48e-3)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.58e-2)" SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 178.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.7;Late spermatids: 76.3;Proximal enterocytes: 53.3;Proximal tubular cells: 67.5;Undifferentiated cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 6 Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" SLC25A11 "OGC, SLC20A4" ENSG00000108528 "Solute carrier family 25 member 11" Q02978 17 4937130-4940053 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 225.5;skeletal muscle: 303.6;tongue: 432.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021167 Approved NA NA 25000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 7 "HPA021167: AB_1857021" "unprognostic (8.58e-2)" "unprognostic (4.06e-3)" "unprognostic (9.43e-2)" "unprognostic (2.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (4.86e-1)" "unprognostic (9.48e-2)" "prognostic favorable (6.41e-6)" "unprognostic (2.84e-1)" "prognostic favorable (2.84e-9)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 34.6;Spermatocytes: 31.8;Spermatogonia: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060316 Approved Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium assembly" Mitochondria "HPA060316: AB_2684251" "unprognostic (1.65e-2)" "prognostic favorable (1.72e-5)" "unprognostic (1.82e-1)" "unprognostic (2.74e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (3.36e-3)" "unprognostic (8.92e-3)" "unprognostic (3.52e-2)" "unprognostic (2.95e-3)" "prognostic favorable (1.78e-4)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.52e-6)" "unprognostic (6.05e-2)" "unprognostic (1.12e-1)" "unprognostic (6.92e-2)" "prognostic favorable (1.39e-5)" SLC25A15 "D13S327, HHH, ORC1, ORNT1" ENSG00000102743 "Solute carrier family 25 member 15" Q9Y619 13 40789412-40812460 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 36.5;liver: 85.5;pancreas: 50.2" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 113.1;Hepatocytes: 153.3;Proximal enterocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042146 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "HPA042146: AB_2677874" "unprognostic (4.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.85e-1)" "prognostic favorable (2.16e-4)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "prognostic favorable (1.74e-4)" "unprognostic (4.04e-3)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (5.46e-4)" SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 6: Ovarian stromal cells - Transcription" 1 Peroxisomes "HPA052708: AB_2681924, HPA060972: AB_2684400" "unprognostic (2.75e-1)" "unprognostic (1.11e-3)" "unprognostic (1.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (5.59e-2)" "unprognostic (8.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 129.5;liver: 108.8" "Group enriched" "Detected in some" 9 "Astrocytes: 185.2;Hepatocytes: 56.1" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Astrocytes - Unknown function" 5 Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 93.8;Langerhans cells: 194.0;Spermatocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" Mitochondria "HPA021936: " "unprognostic (2.28e-1)" "unprognostic (7.05e-3)" "unprognostic (8.21e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.21e-7)" "unprognostic (6.71e-2)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.77e-3)" "unprognostic (2.71e-3)" "unprognostic (3.58e-2)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" SLC25A2 ORNT2 ENSG00000120329 "Solute carrier family 25 member 2" Q9BXI2 5 141302635-141304049 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 6.4" "Group enriched" "Detected in some" 23 "Early spermatids: 22.5;Late spermatids: 10.7;Spermatocytes: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" HPA042146 Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA042146: AB_2677874" "unprognostic (1.55e-1)" "unprognostic (3.53e-1)" "unprognostic (4.63e-2)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (4.72e-3)" "unprognostic (2.81e-1)" "unprognostic (2.62e-2)" "unprognostic (6.69e-2)" "unprognostic (1.17e-1)" "unprognostic (8.82e-10)" "unprognostic (2.56e-1)" "unprognostic (1.87e-1)" "unprognostic (1.26e-2)" "unprognostic (1.14e-1)" SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 143.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.7;Distal enterocytes: 34.7;Hepatocytes: 62.0;Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" SLC25A22 "EIEE3, FLJ13044, GC-1, GC1, NET44" ENSG00000177542 "Solute carrier family 25 member 22" Q9H936 11 790475-798281 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 118.6;pancreas: 81.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 131.7;Cone photoreceptor cells: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014662 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 25: Bipolar cells - Visual perception" Mitochondria Nucleoplasm "HPA014662: AB_10600808" "unprognostic (1.01e-2)" "unprognostic (2.12e-1)" "unprognostic (7.28e-2)" "unprognostic (4.68e-2)" "unprognostic (2.09e-3)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (8.67e-3)" "unprognostic (4.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (8.97e-3)" "unprognostic (2.61e-2)" "unprognostic (8.47e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 390.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.7;Proximal enterocytes: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 1 Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" SLC25A26 ENSG00000144741 "Solute carrier family 25 member 26" Q70HW3 3 66133610-66388116 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 127.5;Oocytes: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026887 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "HPA026887: AB_2189921" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (7.83e-2)" "unprognostic (7.94e-2)" "unprognostic (5.38e-2)" "unprognostic (1.53e-1)" "unprognostic (3.54e-1)" "unprognostic (9.21e-2)" "unprognostic (8.43e-2)" "prognostic favorable (1.73e-5)" "unprognostic (4.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-1)" SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1707.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 83000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 15: Non-specific - Mixed function" Mitochondria "HPA045709: AB_10965843" "unprognostic (1.16e-2)" "unprognostic (4.68e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-2)" "unprognostic (6.38e-2)" "unprognostic (3.25e-3)" "unprognostic (9.41e-2)" "unprognostic (4.98e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "prognostic favorable (8.11e-7)" "unprognostic (3.45e-1)" "unprognostic (2.99e-1)" "unprognostic (8.66e-3)" "unprognostic (4.72e-2)" SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 272 "testis: 45.9" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 170.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Enhanced Mitochondria NA NA "Cluster 10: Testis - Spermatid development" "Cluster 24: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Mitochondria "HPA015064: AB_1847691, HPA016841: AB_1847690, HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.70e-1)" "unprognostic (5.32e-1)" SLC25A33 "BMSC-MCP, MGC4399, PNC1" ENSG00000171612 "Solute carrier family 25 member 33" Q9BSK2 1 9539465-9585173 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 26.4" "Cell type enhanced" "Detected in all" "Early spermatids: 195.8;Late spermatids: 254.8;Muller glia cells: 172.3;Spermatocytes: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049982 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA049982: AB_2680981" "unprognostic (1.61e-1)" "prognostic favorable (4.86e-4)" "unprognostic (2.94e-2)" "unprognostic (4.80e-2)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.18e-2)" "prognostic favorable (7.02e-4)" "unprognostic (1.88e-3)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (4.55e-3)" "unprognostic (7.27e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (3.77e-2)" SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 15.8;heart muscle: 13.9;intestine: 13.4;skeletal muscle: 36.5;tongue: 44.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 16.5;Paneth cells: 12.4;Proximal enterocytes: 40.3;Skeletal myocytes: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 17.9;Syncytiotrophoblasts: 15.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: AB_1857048" "unprognostic (4.12e-2)" "unprognostic (9.98e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (6.52e-2)" "unprognostic (3.46e-1)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "unprognostic (1.99e-2)" "unprognostic (2.47e-2)" "unprognostic (3.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (6.03e-2)" "prognostic favorable (1.55e-4)" SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 56: Non-specific - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 19: NK-cells - Adaptive immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" SLC25A39 "CGI-69, FLJ22407" ENSG00000013306 "Solute carrier family 25 member 39" Q9BZJ4 17 44319625-44324870 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Heme biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 457.9;Erythroid cells: 618.9;Late spermatids: 752.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026785 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 40: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 1: Erythroid cells - Oxygen transport" "HPA026785: AB_10601715" "unprognostic (8.10e-2)" "unprognostic (2.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.29e-1)" "unprognostic (6.04e-2)" "unprognostic (2.35e-3)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "prognostic favorable (3.58e-5)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.22e-1)" "unprognostic (3.21e-2)" SLC25A4 "AAC1, ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 237.2;skeletal muscle: 184.0;tongue: 333.2" "Cell type enriched" "Detected in all" 6 "Cardiomyocytes: 6374.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" SLC25A40 MCFP ENSG00000075303 "Solute carrier family 25 member 40" Q8TBP6 7 87833568-87876360 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055197 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 29: Monocytes - Innate immune response" "HPA055197: AB_2682735" "unprognostic (4.19e-2)" "unprognostic (1.01e-1)" "unprognostic (7.30e-2)" "unprognostic (2.15e-1)" "unprognostic (8.80e-2)" "unprognostic (4.03e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.73e-1)" "unprognostic (3.51e-2)" "unprognostic (3.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.78e-2)" "prognostic favorable (1.52e-5)" "unprognostic (8.42e-2)" "unprognostic (2.45e-1)" "unprognostic (2.88e-2)" "unprognostic (4.85e-2)" SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 65.0;Hepatocytes: 52.3;Rod photoreceptor cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.8;MAIT T-cell: 1.5;memory B-cell: 3.3;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.5;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.8" "Cancer enhanced" "Detected in all" "Myeloma: 22.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" 3 Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" SLC25A44 "FLJ90431, KIAA0446" ENSG00000160785 "Solute carrier family 25 member 44" Q96H78 1 156193932-156212796 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 132.3;Salivary duct cells: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065411 Approved Nucleoplasm,Mitochondria NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA065411: AB_2685486" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-1)" "unprognostic (2.44e-3)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.72e-2)" "unprognostic (8.92e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "prognostic favorable (2.49e-4)" "unprognostic (3.37e-2)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (8.13e-2)" "unprognostic (2.37e-1)" SLC25A45 ENSG00000162241 "Solute carrier family 25 member 45" Q8N413 11 65375192-65383701 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 33.2" "Cell type enhanced" "Detected in many" "dendritic cells: 50.7;Granulosa cells: 58.3;NK-cells: 64.8;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 13.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042495, HPA050821" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" Cytosol "HPA042495: , HPA050821: AB_2681249" "unprognostic (3.73e-2)" "unprognostic (2.19e-3)" "unprognostic (8.44e-4)" "unprognostic (6.17e-3)" "unprognostic (2.57e-2)" "unprognostic (2.84e-7)" "unprognostic (7.57e-3)" "unprognostic (4.59e-2)" "unprognostic (1.44e-1)" "unprognostic (4.06e-2)" "prognostic favorable (2.83e-4)" "unprognostic (1.96e-1)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.54e-1)" "unprognostic (6.18e-2)" "unprognostic (1.43e-1)" SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 251.1;Late spermatids: 456.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Late spermatids - Unknown function" 15 Mitochondria "HPA039601: AB_2676592, HPA071582: AB_2686422" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "prognostic favorable (8.41e-4)" "unprognostic (4.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.98e-1)" SLC25A48 FLJ44862 ENSG00000145832 "Solute carrier family 25 member 48" Q6ZT89 5 135476913-135889770 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.2;kidney: 7.2;skeletal muscle: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 29.4;Oocytes: 10.3;Proximal enterocytes: 13.3;Proximal tubular cells: 34.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.9;Rhabdoid: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014674 Uncertain Approved "Intermediate filaments,Actin filaments" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 "Intermediate filaments" "Actin filaments" "HPA014674: AB_1859512" "unprognostic (2.09e-1)" "unprognostic (2.24e-1)" "unprognostic (6.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.96e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-7)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" SLC25A5 "2F1, ANT2, T2, T3" ENSG00000005022 "Solute carrier family 25 member 5" P05141 X 119468422-119471396 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Chromosome partition, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2075.7;Proximal enterocytes: 2855.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 640000 "Cluster 33: Non-specific - ATP binding" "Cluster 48: Stomach - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 5: Enterocytes - Absorption" 1 Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.25e-2)" "prognostic favorable (7.35e-4)" "prognostic favorable (7.47e-4)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (1.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.41e-1)" "unprognostic (2.65e-1)" "unprognostic (4.36e-2)" "unprognostic (3.03e-1)" SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 38.9;Late spermatids: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 49: Non-specific - Transcription" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 10.1" "Group enriched" "Detected in some" 4 "Early spermatids: 48.5;Late spermatids: 101.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 36: Late spermatids - Unknown function" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (8.97e-2)" "unprognostic (4.85e-2)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (2.50e-1)" "unprognostic (9.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.30e-4)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" SLC25A53 MCART6 ENSG00000269743 "Solute carrier family 25 member 53" Q5H9E4 X 104099214-104157009 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.4;lymphoid tissue: 1.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8" "Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034959 Uncertain NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 39: Non-specific - Basic cellular processes" "HPA034959: AB_10602025" "unprognostic (4.70e-2)" "unprognostic (1.16e-2)" "unprognostic (7.16e-3)" "unprognostic (5.94e-2)" "unprognostic (2.68e-2)" "unprognostic (5.23e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" "unprognostic (4.45e-3)" "unprognostic (7.94e-2)" "unprognostic (9.76e-5)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (3.48e-2)" "unprognostic (1.74e-1)" "unprognostic (3.53e-1)" "unprognostic (1.76e-2)" SLC25A6 "ANT3, ANT3Y, MGC17525" ENSG00000169100 "Solute carrier family 25 member 6" P12236 X 1386152-1392113 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Apoptosis, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 450000 "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 12 Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.13e-1)" "unprognostic (1.65e-2)" "unprognostic (4.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-3)" "unprognostic (1.34e-1)" "unprognostic (8.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (4.57e-3)" SLC26A1 "EDM4, SAT-1" ENSG00000145217 "Solute carrier family 26 member 1" Q9H2B4 4 979073-993440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Excitatory neurons: 4.3;Extravillous trophoblasts: 3.8;Hepatocytes: 9.4;Inhibitory neurons: 4.2;Oligodendrocyte precursor cells: 5.2;Proximal enterocytes: 6.6;Proximal tubular cells: 6.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 5.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041654 Uncertain Approved Microtubules NA NA "Cluster 83: Liver - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" Microtubules "HPA041654: AB_10796350" "unprognostic (1.96e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-1)" "unprognostic (4.91e-2)" "unprognostic (1.74e-1)" "unprognostic (2.67e-4)" "unprognostic (5.13e-2)" "unprognostic (5.82e-2)" "unprognostic (2.16e-1)" "unprognostic (3.88e-2)" "unprognostic (1.53e-3)" "unprognostic (2.92e-2)" "prognostic favorable (1.19e-4)" "unprognostic (1.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.65e-3)" SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 1 "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 204.5" "Group enriched" "Detected in all" 4 "Distal enterocytes: 2533.4;Glandular and luminal cells: 676.7;Syncytiotrophoblasts: 775.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1084.0" "Cell type enriched" "Detected in some" 8 "Distal enterocytes: 3000.7" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "colorectal cancer: 16.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036055 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" SLC26A4 "DFNB4, PDS" ENSG00000091137 "Solute carrier family 26 member 4" O43511 7 107660828-107717809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "thyroid gland: 256.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.2;Inhibitory neurons: 52.1;Ionocytes: 47.9;Lymphatic endothelial cells: 24.7;Serous glandular cells: 24.7" "Cancer enriched" "Detected in some" 8 "thyroid cancer: 37.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 8 "B-cells: 1.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 16.1" "Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in many" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in many" "hippocampal formation: 6.6" HPA042860 Approved NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 8: Neurons - Neuronal signaling" "HPA042860: AB_10796680" "unprognostic (1.19e-2)" "unprognostic (4.84e-2)" "unprognostic (5.44e-2)" "unprognostic (8.44e-2)" "unprognostic (3.25e-2)" "unprognostic (3.26e-2)" "unprognostic (6.69e-2)" "unprognostic (1.85e-1)" "unprognostic (5.72e-2)" "unprognostic (9.58e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-2)" "unprognostic (1.39e-1)" SLC26A6 DKFZp586E1422 ENSG00000225697 "Solute carrier family 26 member 6" Q9BXS9 3 48625723-48635493 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Chloride channel, Ion channel, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.0;Intestinal goblet cells: 35.0;Paneth cells: 37.2;Proximal enterocytes: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048363, HPA072381" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Cytosol "HPA048363: AB_2680371, HPA072381: " "unprognostic (1.54e-1)" "unprognostic (4.94e-2)" "unprognostic (3.34e-1)" "unprognostic (3.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.92e-4)" "unprognostic (2.39e-1)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (9.66e-3)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.58e-2)" SLC26A8 TAT1 ENSG00000112053 "Solute carrier family 26 member 8" Q96RN1 6 35943516-36024868 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Differentiation, Ion transport, Meiosis, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 42.8" "Cell type enhanced" "Detected in some" "Early spermatids: 68.5;Excitatory neurons: 15.3;Inhibitory neurons: 11.6;Late spermatids: 10.0;Spermatocytes: 50.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Stomach - Neutrophils, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038081 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "HPA038081: AB_10670653" "unprognostic (8.18e-2)" "unprognostic (1.74e-1)" "unprognostic (6.71e-2)" "unprognostic (1.31e-2)" "unprognostic (2.46e-1)" "unprognostic (7.07e-3)" "unprognostic (2.93e-1)" "unprognostic (6.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (1.85e-1)" "unprognostic (3.78e-1)" "unprognostic (4.63e-6)" "unprognostic (7.14e-2)" "unprognostic (4.24e-1)" "unprognostic (2.31e-1)" "unprognostic (5.24e-8)" SLC26A9 ENSG00000174502 "Solute carrier family 26 member 9" Q7LBE3 1 205913048-205943460 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "salivary gland: 70.4;stomach 1: 33.1" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 36.6;Cardiomyocytes: 33.2;Gastric mucus-secreting cells: 25.4;Proximal tubular cells: 24.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.5;pancreatic cancer: 3.6" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA051485 Enhanced Approved "Cell Junctions" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Cell Junctions" "HPA051485: AB_2681503" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-1)" "unprognostic (1.83e-2)" "prognostic favorable (8.55e-5)" "unprognostic (1.26e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (8.85e-2)" "unprognostic (3.41e-1)" "unprognostic (2.43e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (7.45e-3)" "unprognostic (2.01e-1)" SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 80.2;Oligodendrocytes: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.0;liver: 279.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 54.7;Cytotrophoblasts: 259.6;Hepatocytes: 171.6;Proximal enterocytes: 78.3;Proximal tubular cells: 96.0;Syncytiotrophoblasts: 53.8" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Region enhanced" "Detected in all" "choroid plexus: 20.1" "Immune cell enriched" "Detected in some" 30 "basophil: 63.7" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026089 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 79.4;Lymphatic endothelial cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006935, HPA067508" Enhanced Enhanced "Endoplasmic reticulum" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 17: Choroid plexus - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "HPA006935: AB_1080003, HPA067508: AB_2685857" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (2.70e-2)" "unprognostic (4.85e-2)" "unprognostic (6.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (3.39e-2)" "prognostic favorable (5.23e-4)" "unprognostic (4.67e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.95e-1)" "unprognostic (4.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.08e-1)" SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 80: Non-specific - Endocytosis" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 24 "liver: 999.1" "Group enriched" "Detected in all" 5 "Early spermatids: 135.5;Hepatocytes: 338.8;Late spermatids: 456.0" "Cancer enriched" "Detected in all" 26 "liver cancer: 49.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007292, CAB056160, CAB068239" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Plasma proteins" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 43: Hepatocytes - Metabolism" "CAB056160: AB_2665590, CAB068239: AB_2665592, HPA007292: AB_1857064" "unprognostic (5.97e-2)" "unprognostic (9.12e-2)" "unprognostic (9.95e-2)" "unprognostic (6.36e-3)" "unprognostic (2.52e-1)" "unprognostic (7.46e-2)" "prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.66e-4)" "unprognostic (2.27e-1)" "unprognostic (3.33e-2)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.6;fallopian tube: 20.6;heart muscle: 22.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 32.0;Cytotrophoblasts: 54.9;Early spermatids: 19.2;Extravillous trophoblasts: 36.4;Granulosa cells: 40.7;Muller glia cells: 25.2;Secretory cells: 20.2;Syncytiotrophoblasts: 29.9" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.1" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 24: Cytotrophoblasts - Mitochondria" "Nuclear bodies" "HPA008987: AB_1857065" "unprognostic (5.39e-5)" "unprognostic (4.79e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-1)" "unprognostic (3.55e-1)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" "unprognostic (2.14e-1)" "unprognostic (2.54e-2)" "unprognostic (9.66e-4)" SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 47.7;kidney: 46.9;liver: 108.6" "Group enriched" "Detected in some" 10 "Hepatocytes: 34.9;Hofbauer cells: 45.0;Proximal enterocytes: 87.5;Proximal tubular cells: 80.3" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Kidney cancer: 3.9" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 89.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 11.7;Distal enterocytes: 27.1;Paneth cells: 29.0;Proximal enterocytes: 42.3;Undifferentiated cells: 23.1" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Gastric cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "Golgi apparatus" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" SLC28A3 CNT3 ENSG00000197506 "Solute carrier family 28 member 3" Q9HAS3 9 84275457-84340758 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 11.6;Ductal cells: 29.1;Ionocytes: 15.1;Mesothelial cells: 25.7;Mucus glandular cells: 25.8;Secretory cells: 15.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 22 "choroid plexus: 47.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.5;Leukemia: 2.6" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023311, HPA024729" Approved NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA023311: AB_1857067, HPA024729: AB_1857069" "prognostic favorable (3.37e-4)" "unprognostic (1.28e-2)" "unprognostic (3.01e-1)" "unprognostic (2.50e-1)" "unprognostic (2.79e-1)" "unprognostic (1.82e-3)" "unprognostic (3.74e-1)" "unprognostic (2.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.20e-1)" "unprognostic (5.06e-2)" "unprognostic (4.13e-2)" "unprognostic (1.54e-7)" "unprognostic (1.03e-1)" "unprognostic (9.87e-2)" "unprognostic (8.75e-2)" "unprognostic (4.03e-2)" SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.2;Extravillous trophoblasts: 243.5;Granulosa cells: 104.4;Oocytes: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1049.2" "Lineage enriched" "Detected in all" 26 "granulocytes: 1049.2" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" SLC29A2 "DER12, ENT2, HNP36" ENSG00000174669 "Solute carrier family 29 member 2" Q14542 11 66362521-66372214 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 87.6;tongue: 45.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.9;Skeletal myocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018168 Approved NA Yes "Cluster 11: T-cells - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA018168: AB_1857077" "unprognostic (3.20e-2)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.37e-1)" "unprognostic (5.08e-2)" "unprognostic (5.64e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.09e-1)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.38e-3)" SLC29A3 "ENT3, FLJ11160, hENT3" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319259-71381423 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.3;Extravillous trophoblasts: 49.5;Hofbauer cells: 29.9;Oocytes: 22.8;Syncytiotrophoblasts: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046085, HPA054976, HPA057905" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus, Vesicles" "HPA046085: AB_2679531, HPA054976: AB_2682659, HPA057905: AB_2683550" "unprognostic (1.73e-1)" "unprognostic (2.38e-3)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (1.28e-1)" "unprognostic (4.71e-1)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (3.37e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.43e-3)" SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.8;brain: 31.6;choroid plexus: 36.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 53.2;Horizontal cells: 61.1;Oocytes: 44.8;Pancreatic endocrine cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT-1, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 95.3;skin 1: 77.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 805.1;Extravillous trophoblasts: 574.4;Muller glia cells: 355.3;Syncytiotrophoblasts: 2375.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 14: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" SLC2A10 "GLUT-10, GLUT10" ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 40.5;Intestinal goblet cells: 70.8;Prostatic glandular cells: 45.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 38.6" "Immune cell enriched" "Detected in single" 82 "basophil: 20.8" "Lineage enriched" "Detected in single" 82 "granulocytes: 20.8" "Cancer enhanced" "Detected in many" "breast cancer: 30.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" SLC2A11 GLUT11 ENSG00000133460 "Solute carrier family 2 member 11" Q9BYW1 22 23856703-23886312 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 181.8;Rod photoreceptor cells: 209.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "HPA042960, HPA071184" Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "Cell Junctions" Nucleoplasm "HPA042960: AB_2678241, HPA071184: AB_2686355" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (3.69e-2)" "unprognostic (6.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.32e-1)" "unprognostic (4.24e-2)" "unprognostic (1.60e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "prognostic favorable (3.83e-4)" "unprognostic (2.32e-1)" "prognostic favorable (5.77e-7)" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (6.29e-2)" SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "choroid plexus: 105.3" "Cell type enhanced" "Detected in many" "Astrocytes: 23.5;Prostatic glandular cells: 69.0;Syncytiotrophoblasts: 40.3" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Region enriched" "Detected in all" 11 "choroid plexus: 184.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 19.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Prostatic glandular cells - Transcription" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" SLC2A13 HMIT ENSG00000151229 "Solute carrier family 2 member 13" Q96QE2 12 39755025-40106089 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1;parathyroid gland: 21.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 489.9;Inhibitory neurons: 445.3;Oligodendrocyte precursor cells: 330.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006584, HPA061679" Enhanced Approved "Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 3 "Nuclear membrane" "HPA006584: AB_1849755, HPA061679: " "unprognostic (1.66e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (9.62e-2)" "unprognostic (1.04e-1)" "unprognostic (3.31e-1)" "unprognostic (4.06e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (2.25e-2)" "unprognostic (2.12e-3)" "unprognostic (4.07e-2)" "unprognostic (6.34e-2)" "unprognostic (1.24e-2)" "unprognostic (9.16e-2)" SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 79.4" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 51.4" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "testis cancer: 32.7" "Skin - Sebaceous gland cells, Testis - Early spermatids" HPA006539 Supported Supported "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" SLC2A2 "GLUT-2, GLUT2" ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 810.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 407.5" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.6;Kidney cancer: 6.4;liver cancer: 4.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997, HPA069490" Enhanced Supported "Plasma membrane" NA NA "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860, HPA069490: " "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" SLC2A3 GLUT3 ENSG00000059804 "Solute carrier family 2 member 3" P11169 12 7919230-7936187 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 423.6" "Cell type enhanced" "Detected in many" "Adipocytes: 355.7;B-cells: 326.6;Endothelial cells: 368.2;Extravillous trophoblasts: 416.7;granulocytes: 423.8;Langerhans cells: 744.0;Macrophages: 332.2;Schwann cells: 322.6;T-cells: 353.6" "Cancer enriched" "Detected in all" 7 "testis cancer: 107.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 166.9;neutrophil: 225.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 225.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 1031.5" "CAB002763, HPA006539" Approved Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane" "CAB002763: , HPA006539: AB_1078984" "unprognostic (9.20e-2)" "unprognostic (9.63e-3)" "prognostic unfavorable (8.58e-4)" "unprognostic (2.65e-1)" "unprognostic (5.29e-3)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (8.27e-2)" "unprognostic (2.35e-1)" "unprognostic (3.83e-2)" "unprognostic (8.47e-3)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.36e-8)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.70e-1)" "unprognostic (1.14e-2)" "unprognostic (2.91e-3)" SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.7;skeletal muscle: 215.7" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 125.8;Skeletal myocytes: 52.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.7;intestine: 105.9;skeletal muscle: 76.1;testis: 74.1" "Cell type enhanced" "Detected in many" "Early spermatids: 75.6;Paneth cells: 57.9;Proximal enterocytes: 189.6;Spermatocytes: 70.4" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in many" 8 "Leukemia: 40.5;lymphoma: 53.5;Myeloma: 32.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Proximal enterocytes - Digestion" 8 "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" SLC2A6 "GLUT6, GLUT9, HSA011372" ENSG00000160326 "Solute carrier family 2 member 6" Q9UGQ3 9 133471094-133479127 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;lymphoid tissue: 12.9" "Cell type enriched" "Detected in many" 4 "monocytes: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042272, CAB046014" Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 1 "CAB046014: AB_2270444, HPA042272: AB_2677924" "unprognostic (2.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (1.71e-3)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.93e-2)" "unprognostic (1.05e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (1.02e-11)" "unprognostic (7.24e-2)" "unprognostic (3.43e-2)" "unprognostic (9.36e-2)" "unprognostic (6.28e-3)" SLC2A7 GLUT7 ENSG00000197241 "Solute carrier family 2 member 7" Q6PXP3 1 9002973-9026423 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "intestine: 2.4" "Cell type enhanced" "Detected in single" "Astrocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA039931 Uncertain NA NA "Cluster 25: Small intestine - Absorption" "Cluster 34: Testis cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA039931: AB_10671046" "unprognostic (4.19e-2)" "unprognostic (3.68e-1)" "unprognostic (1.96e-2)" "unprognostic (2.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.43e-1)" "unprognostic (9.05e-2)" "unprognostic (5.69e-4)" "unprognostic (5.09e-2)" "unprognostic (7.12e-2)" "unprognostic (1.60e-1)" "unprognostic (3.35e-1)" SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 133.1;Endometrial stromal cells: 85.5;Late spermatids: 317.3;Spermatocytes: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 76.1" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 44: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favorable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favorable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favorable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.2;liver: 20.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 48.9;Basal respiratory cells: 24.9;Proximal tubular cells: 73.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 14.0;head and neck cancer: 11.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 83.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 79.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219959018 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 23.8;liver: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.5;Early spermatids: 52.3;Hepatocytes: 128.4;Late spermatids: 38.6;Proximal enterocytes: 43.3" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.6" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 96.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.9;Glandular and luminal cells: 93.9;Proximal tubular cells: 26.3;Syncytiotrophoblasts: 88.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 55 Vesicles "HPA017979: AB_1857085" "unprognostic (4.87e-2)" "unprognostic (6.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (2.25e-2)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.02e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.86e-6)" "unprognostic (9.38e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 28.8;epididymis: 66.8;testis: 34.2" "Cell type enhanced" "Detected in some" "Early spermatids: 15.6;Excitatory neurons: 15.1;Late spermatids: 34.3;Oocytes: 11.0;Peritubular cells: 10.4;Sertoli cells: 13.6;Spermatocytes: 12.8;Spermatogonia: 9.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Sertoli cells" "Group enriched" "Detected in all" 4 "amygdala: 130.8;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 7 "amygdala: 24.3;cerebral cortex: 72.0;hippocampal formation: 56.1" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 63: Testis - Spermatid development" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 22 Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093991-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA035373: AB_10794630" "unprognostic (9.81e-3)" "unprognostic (3.33e-1)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.47e-2)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" SLC30A6 "FLJ31101, ZNT6" ENSG00000152683 "Solute carrier family 30 member 6" Q6NXT4 2 32165841-32224379 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055032, HPA057328" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" "Golgi apparatus" "HPA055032: AB_2682677, HPA057328: AB_2683411" "unprognostic (5.61e-2)" "unprognostic (9.11e-3)" "unprognostic (1.05e-3)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (2.98e-1)" "unprognostic (9.47e-2)" "unprognostic (1.88e-1)" "unprognostic (3.30e-3)" "unprognostic (7.05e-2)" "unprognostic (3.06e-2)" "unprognostic (3.51e-1)" "unprognostic (3.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" SLC30A7 "ZNT7, ZnTL2" ENSG00000162695 "Solute carrier family 30 member 7" Q8NEW0 1 100896076-100981757 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018034 Uncertain Supported "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" "HPA018034: AB_1857089" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (8.05e-3)" "unprognostic (1.79e-1)" "unprognostic (2.50e-1)" "unprognostic (3.18e-1)" "unprognostic (2.89e-3)" "unprognostic (1.24e-1)" "unprognostic (1.61e-1)" "unprognostic (1.11e-3)" "unprognostic (2.78e-2)" "unprognostic (1.95e-1)" "unprognostic (5.46e-2)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (3.37e-1)" SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 50.7" "Cell type enriched" "Detected in some" 20 "Pancreatic endocrine cells: 140.9" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 18.5;Sarcoma: 16.7" "Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 5.5" "HPA065953, HPA076165" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 66 "Vesicles, Plasma membrane" "HPA065953: , HPA076165: AB_2732304" "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" SLC30A9 "C4orf1, GAC63, HUEL, ZNT9" ENSG00000014824 "Solute carrier family 30 member 9" Q6PML9 4 41990502-42090461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transcription, Transcription regulation, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004014 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" "HPA004014: AB_1080005" "unprognostic (4.26e-2)" "unprognostic (2.20e-1)" "unprognostic (1.31e-3)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.19e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-2)" "unprognostic (1.43e-1)" "unprognostic (1.55e-1)" "unprognostic (6.99e-2)" "prognostic favorable (2.86e-14)" "unprognostic (4.67e-2)" "unprognostic (1.34e-1)" "unprognostic (2.22e-2)" "unprognostic (1.39e-2)" SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.6;Prostatic glandular cells: 90.9;Serous glandular cells: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.1" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" "HPA013810: AB_1857095" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (5.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (1.22e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.51e-2)" SLC31A2 "COPT2, CTR2, hCTR2" ENSG00000136867 "Solute carrier family 31 member 2" O15432 9 113150976-113164140 "Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "parathyroid gland: 550.1;salivary gland: 397.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 131.9;monocytes: 364.0;Oligodendrocytes: 105.9;Serous glandular cells: 227.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 12 "classical monocyte: 225.9;intermediate monocyte: 331.5;myeloid DC: 134.5;neutrophil: 357.2;non-classical monocyte: 424.7" "Group enriched" "Detected in all" 46 "dendritic cells: 134.5;granulocytes: 357.2;monocytes: 424.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.7" "Colon - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014861, CAB080265, CAB080267" Supported Approved "Nuclear speckles,Plasma membrane,Intermediate filaments" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Plasma membrane" "Nuclear speckles, Intermediate filaments" "CAB080265: , CAB080267: , HPA014861: AB_1857098" "unprognostic (2.26e-1)" "unprognostic (7.20e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (5.63e-2)" "unprognostic (3.31e-2)" "unprognostic (2.24e-1)" "unprognostic (3.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.86e-1)" "unprognostic (6.05e-3)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" "unprognostic (8.89e-2)" SLC32A1 "bA122O1.1, VGAT, VIAAT" ENSG00000101438 "Solute carrier family 32 member 1" Q9H598 20 38724486-38729372 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 44.5" "Group enriched" "Detected in some" 14 "dendritic cells: 68.2;Horizontal cells: 62.9;Inhibitory neurons: 19.8" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037156, HPA058859, HPA059985" Enhanced Supported Uncertain Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "CAB037156: AB_532294, HPA058859: AB_2683836, HPA059985: AB_2684187" "unprognostic (1.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" SLC33A1 "ACATN, AT-1, AT1, SPG42" ENSG00000169359 "Solute carrier family 33 member 1" O00400 3 155821024-155854456 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Cataract, Deafness, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042430 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Vesicles, Cytosol" "HPA042430: AB_10806238" "unprognostic (5.12e-3)" "unprognostic (7.78e-2)" "unprognostic (1.13e-2)" "unprognostic (7.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-2)" "unprognostic (9.57e-2)" "unprognostic (5.65e-2)" "unprognostic (6.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.73e-2)" "unprognostic (5.74e-2)" SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 149.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 101.4" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Leukemia - Hemostasis" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 729.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 672.8;Alveolar cells type 2: 1668.8" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Group enriched" "Detected in many" 6 "cerebellum: 5.4;choroid plexus: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.2;ovarian cancer: 115.1;pancreatic cancer: 54.6;Uterine cancer: 52.8" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 57: Lung - Lung function" "Cluster 5: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" SLC34A3 "FLJ38680, NPTIIc" ENSG00000198569 "Solute carrier family 34 member 3" Q8N130 9 137230757-137236555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 9.4;kidney: 13.2" "Group enriched" "Detected in some" 11 "Proximal enterocytes: 77.3;Proximal tubular cells: 22.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA023776 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA023776: AB_1857102" "unprognostic (2.69e-1)" "unprognostic (4.16e-1)" "unprognostic (9.08e-3)" "unprognostic (1.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.05e-2)" "unprognostic (9.84e-3)" "unprognostic (2.05e-2)" "unprognostic (2.20e-2)" "unprognostic (5.94e-2)" "unprognostic (1.94e-2)" "unprognostic (9.12e-2)" "unprognostic (5.80e-2)" "unprognostic (2.20e-1)" SLC35A2 "UGALT, UGAT, UGT, UGT1, UGT2, UGTL" ENSG00000102100 "Solute carrier family 35 member A2" P78381 X 48903180-48911958 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036087 Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Breast glandular cells - Lactation" 1 "Golgi apparatus" "HPA036087: AB_10604093" "prognostic unfavorable (3.16e-4)" "unprognostic (3.34e-1)" "unprognostic (4.88e-3)" "unprognostic (1.11e-1)" "unprognostic (8.15e-3)" "unprognostic (4.25e-3)" "prognostic unfavorable (9.64e-5)" "unprognostic (3.47e-1)" "unprognostic (2.50e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-3)" "unprognostic (9.58e-2)" "unprognostic (3.16e-2)" "prognostic favorable (8.23e-4)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 118.3" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" SLC35A4 ENSG00000176087 "Solute carrier family 35 member A4" "L0R6Q1, Q96G79" 5 140564446-140569100 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 128.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062210 Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Late spermatids - Unknown function" 23 Nucleoplasm Cytosol "HPA062210: AB_2684712" "unprognostic (3.01e-3)" "unprognostic (1.35e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.46e-2)" "unprognostic (1.65e-2)" "unprognostic (1.91e-3)" "unprognostic (9.63e-2)" "unprognostic (3.61e-2)" "unprognostic (9.32e-2)" "unprognostic (1.78e-2)" "unprognostic (2.87e-1)" "prognostic favorable (4.56e-5)" "unprognostic (2.96e-2)" "unprognostic (3.04e-2)" "unprognostic (2.06e-2)" "unprognostic (1.55e-1)" SLC35A5 FLJ20730 ENSG00000138459 "Solute carrier family 35 member A5" Q9BS91 3 112561709-112585579 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035519, HPA057964" Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Early spermatids - Spermatogenesis" 4 "Golgi apparatus" "HPA035519: AB_10601487, HPA057964: AB_2683566" "unprognostic (7.89e-2)" "unprognostic (2.33e-1)" "unprognostic (7.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.45e-1)" "unprognostic (4.78e-2)" "unprognostic (8.60e-3)" "unprognostic (2.60e-1)" "unprognostic (8.21e-2)" "unprognostic (3.51e-1)" "prognostic favorable (4.10e-5)" "unprognostic (2.26e-1)" "unprognostic (1.97e-1)" "unprognostic (8.05e-2)" "unprognostic (3.42e-1)" SLC35B1 "AXER, UGTREL1" ENSG00000121073 "Solute carrier family 35 member B1" P78383 17 49700934-49709014 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048655, HPA057418" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Plasma cells - Protein processing" 13 "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA048655: AB_2680481, HPA057418: AB_2683432" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (1.09e-3)" "unprognostic (6.36e-2)" "unprognostic (8.31e-2)" "unprognostic (2.86e-3)" "unprognostic (6.17e-3)" "unprognostic (4.39e-2)" "unprognostic (2.47e-2)" "unprognostic (4.00e-3)" "unprognostic (3.37e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (5.69e-7)" "unprognostic (6.28e-2)" "unprognostic (7.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-2)" SLC35B2 UGTrel4 ENSG00000157593 "Solute carrier family 35 member B2" Q8TB61 6 44254096-44257890 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029638 Approved Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 9 Vesicles "HPA029638: AB_10602402" "prognostic unfavorable (7.90e-4)" "unprognostic (2.47e-3)" "unprognostic (2.30e-1)" "unprognostic (1.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.59e-5)" "unprognostic (3.84e-1)" "unprognostic (2.51e-1)" "unprognostic (7.03e-3)" "unprognostic (4.27e-2)" "prognostic favorable (6.07e-4)" "unprognostic (3.60e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" SLC35B3 "C6orf196, CGI-19, dJ453H5.1, PAPST2" ENSG00000124786 "Solute carrier family 35 member B3" Q9H1N7 6 8411435-8435561 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054661, HPA057801" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA054661: AB_2682561, HPA057801: AB_2683532" "unprognostic (2.84e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (1.34e-1)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (4.93e-2)" "unprognostic (5.23e-3)" "unprognostic (5.00e-2)" "unprognostic (9.45e-2)" "unprognostic (9.27e-2)" "unprognostic (3.43e-1)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (3.08e-3)" "unprognostic (3.88e-3)" SLC35B4 "FLJ14697, YEA4" ENSG00000205060 "Solute carrier family 35 member B4" Q969S0 7 134289332-134316930 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 97.9;Syncytiotrophoblasts: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049779 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 25 "HPA049779: AB_2680878" "unprognostic (1.84e-1)" "unprognostic (1.94e-2)" "unprognostic (7.19e-2)" "unprognostic (2.49e-2)" "unprognostic (1.77e-3)" "unprognostic (3.47e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (6.88e-3)" "unprognostic (1.86e-1)" "unprognostic (2.24e-3)" "unprognostic (3.18e-2)" "unprognostic (2.86e-1)" "unprognostic (9.81e-2)" "unprognostic (1.00e-1)" SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 46.6;Proximal enterocytes: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA064001: AB_2685171" "unprognostic (2.62e-2)" "unprognostic (5.16e-2)" "unprognostic (7.82e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (8.22e-2)" "unprognostic (9.40e-2)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "unprognostic (4.09e-2)" "unprognostic (2.73e-1)" "unprognostic (7.68e-2)" "unprognostic (1.83e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.64e-4)" "unprognostic (2.30e-2)" SLC35C2 "bA394O2.1, C20orf5, CGI-15, OVCOV1" ENSG00000080189 "Solute carrier family 35 member C2" Q9NQQ7 20 46345980-46364458 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027011 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "Golgi apparatus" Nucleoplasm "HPA027011: AB_2672082" "unprognostic (7.25e-2)" "unprognostic (1.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.27e-2)" "unprognostic (1.06e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (9.31e-2)" "unprognostic (7.15e-2)" "unprognostic (1.18e-2)" "unprognostic (3.88e-1)" SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 109.0;Proximal enterocytes: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" SLC35D3 FRCL1 ENSG00000182747 "Solute carrier family 35 member D3" Q5M8T2 6 136922301-136925660 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 5.9" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 1.8;Horizontal cells: 1.9;Ionocytes: 1.1;Pancreatic endocrine cells: 1.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.3;stomach cancer: 0.9" "Group enriched" "Detected in many" 7 "basal ganglia: 7.9;hypothalamus: 12.5;midbrain: 4.7;thalamus: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 3.5;lung cancer: 3.3" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Group enriched" "Detected in many" 5 "basal ganglia: 29.6;olfactory bulb: 8.5" "Region enriched" "Detected in many" 6 "basal ganglia: 26.5" "HPA030431, HPA067497" Uncertain Approved "Centriolar satellite" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 57: Platelets - Hemostasis" "Centriolar satellite" "HPA030431: AB_10601716, HPA067497: AB_2685854" "unprognostic (6.56e-2)" "unprognostic (2.97e-1)" "unprognostic (1.43e-1)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" "unprognostic (5.84e-2)" "unprognostic (2.48e-1)" "unprognostic (9.94e-2)" "unprognostic (7.36e-2)" "unprognostic (4.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.62e-1)" "unprognostic (4.45e-1)" "unprognostic (1.03e-1)" SLC35E1 FLJ14251 ENSG00000127526 "Solute carrier family 35 member E1" Q96K37 19 16549831-16572415 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 161.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016570, HPA062214" Approved Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 28: Dendritic cells - Antigen presentation" 3 "Golgi apparatus" "HPA016570: AB_2190214, HPA062214: AB_2684713" "unprognostic (1.76e-2)" "unprognostic (2.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.92e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.35e-2)" "unprognostic (1.04e-1)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (9.07e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (2.54e-1)" "unprognostic (3.75e-2)" SLC35E2B ENSG00000189339 "Solute carrier family 35 member E2B" P0CK96 1 1659529-1692795 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045641, HPA062711" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA045641: AB_2679402, HPA062711: AB_2684844" "unprognostic (9.00e-2)" "unprognostic (2.13e-1)" "unprognostic (8.74e-3)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.64e-4)" "unprognostic (1.18e-1)" "unprognostic (4.09e-2)" "unprognostic (5.70e-2)" "unprognostic (5.83e-2)" "unprognostic (2.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.92e-1)" "unprognostic (2.68e-2)" "unprognostic (6.61e-2)" "unprognostic (2.54e-2)" "prognostic favorable (5.15e-4)" SLC35E3 BLOV1 ENSG00000175782 "Solute carrier family 35 member E3" Q7Z769 12 68746125-68793964 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "monocytes: 204.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049403 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 22 "HPA049403: AB_2680747" "unprognostic (1.49e-1)" "unprognostic (6.47e-2)" "unprognostic (2.19e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.61e-2)" "unprognostic (2.49e-1)" "unprognostic (1.26e-4)" "unprognostic (2.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (6.98e-2)" "unprognostic (6.85e-3)" "unprognostic (1.48e-1)" "unprognostic (3.22e-2)" "unprognostic (2.89e-3)" "unprognostic (1.80e-1)" SLC35E4 ENSG00000100036 "Solute carrier family 35 member E4" Q6ICL7 22 30635781-30669016 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 118.2;Late spermatids: 120.3;Spermatocytes: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049558 Approved Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 21: Testis - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 12 Cytosol "HPA049558: AB_2680817" "unprognostic (2.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.05e-1)" "unprognostic (1.01e-2)" "unprognostic (4.99e-2)" "unprognostic (2.04e-1)" "unprognostic (3.03e-4)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-2)" "unprognostic (2.39e-2)" "unprognostic (3.45e-7)" "unprognostic (2.77e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (8.05e-3)" SLC35F1 "C6orf169, dJ230I3.1" ENSG00000196376 "Solute carrier family 35 member F1" Q5T1Q4 6 117907264-118317676 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;retina: 12.8" "Group enriched" "Detected in some" 8 "Astrocytes: 360.4;Excitatory neurons: 380.8;Inhibitory neurons: 482.3;Oligodendrocyte precursor cells: 1261.7" "Cancer enriched" "Detected in some" 4 "glioma: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.0" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019576 Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 5 Nucleoplasm "Centriolar satellite, Cytosol" "HPA019576: AB_2190216" "unprognostic (1.46e-1)" "unprognostic (5.67e-2)" "unprognostic (7.08e-2)" "unprognostic (1.37e-3)" "unprognostic (3.31e-1)" "unprognostic (4.99e-2)" "unprognostic (1.39e-1)" "unprognostic (4.04e-1)" "unprognostic (3.64e-2)" "unprognostic (3.04e-2)" "unprognostic (4.44e-3)" "unprognostic (2.19e-1)" "unprognostic (8.83e-4)" "unprognostic (3.04e-3)" "unprognostic (6.03e-2)" "unprognostic (8.32e-2)" "unprognostic (2.02e-1)" SLC35F2 FLJ13018 ENSG00000110660 "Solute carrier family 35 member F2" Q8IXU6 11 107790991-107928293 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 31.2;Serous glandular cells: 35.9;Suprabasal keratinocytes: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048185, HPA060150" Enhanced Approved "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "Golgi apparatus" "HPA048185: AB_2680304, HPA060150: " "unprognostic (7.73e-2)" "unprognostic (3.28e-3)" "unprognostic (8.37e-3)" "unprognostic (5.77e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (6.22e-2)" "unprognostic (8.20e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (1.24e-1)" "unprognostic (4.10e-2)" "unprognostic (1.34e-1)" "unprognostic (7.33e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" SLC35F3 FLJ37712 ENSG00000183780 "Solute carrier family 35 member F3" Q8IY50 1 233904676-234324511 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 15.8" "Group enriched" "Detected in many" 6 "Excitatory neurons: 468.8;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 178.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 35 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 35 "dendritic cells: 3.5" "Low cancer specificity" "Detected in many" "Kidney - Intercalated cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051327, HPA061582" Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoli "HPA051327: AB_2681443, HPA061582: AB_2684563" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-2)" "unprognostic (2.69e-5)" "unprognostic (3.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (3.86e-2)" "unprognostic (9.09e-2)" "unprognostic (1.57e-3)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (3.62e-1)" "unprognostic (3.58e-1)" SLC35F4 "C14orf36, FLJ37712" ENSG00000151812 "Solute carrier family 35 member F4" A4IF30 14 57563920-57982194 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 13.4;retina: 6.2;seminal vesicle: 3.4" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 159.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.9" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043853 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA043853: AB_10963083" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "unprognostic (3.56e-1)" "unprognostic (2.66e-4)" "unprognostic (4.88e-2)" "unprognostic (8.64e-2)" "unprognostic (1.38e-1)" "unprognostic (1.76e-2)" "unprognostic (3.94e-2)" "unprognostic (1.39e-1)" "unprognostic (4.03e-3)" "unprognostic (3.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.68e-3)" "unprognostic (9.23e-2)" SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "HPA034828: AB_2674350, HPA049229: AB_2680682" "unprognostic (1.59e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (8.37e-2)" "unprognostic (3.87e-3)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (4.83e-2)" SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 8 Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.4;Early spermatids: 89.5;Excitatory neurons: 32.9;Inhibitory neurons: 40.6;Spermatocytes: 36.2" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Early spermatids - Unknown function" 4 "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" SLC36A1 "LYAAT-1, PAT1, TRAMD3" ENSG00000123643 "Solute carrier family 36 member 1" Q7Z2H8 5 151437046-151492379 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 99.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.1;Early spermatids: 79.9;Excitatory neurons: 89.6;Inhibitory neurons: 59.7;Oligodendrocyte precursor cells: 45.8;Proximal enterocytes: 39.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 199.7" "Group enriched" "Detected in many" 4 "basophil: 21.8;classical monocyte: 8.7;neutrophil: 19.7" "Group enriched" "Detected in many" 5 "granulocytes: 21.8;monocytes: 8.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035937 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA035937: AB_10672995" "unprognostic (5.49e-2)" "unprognostic (4.04e-2)" "unprognostic (1.24e-1)" "unprognostic (8.27e-3)" "unprognostic (1.91e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (6.30e-5)" "unprognostic (1.86e-1)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (5.08e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.83e-6)" "unprognostic (2.66e-2)" "unprognostic (1.03e-2)" "unprognostic (2.49e-1)" "unprognostic (1.42e-1)" SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 65.1;skeletal muscle: 77.2;tongue: 28.7" "Group enriched" "Detected in some" 5 "Proximal tubular cells: 42.5;Skeletal myocytes: 18.5" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 48: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: AB_2190238" "unprognostic (1.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (1.08e-3)" "unprognostic (7.83e-3)" "unprognostic (3.06e-2)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (8.04e-3)" "unprognostic (7.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.74e-1)" "unprognostic (9.45e-3)" "unprognostic (4.20e-2)" SLC37A1 SPX1 ENSG00000160190 "Solute carrier family 37 member 1" P57057 21 42496008-42581440 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 44.5" "Cell type enhanced" "Detected in many" "Early spermatids: 177.0;Late spermatids: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030418, CAB034154" Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Breast glandular cells - Lactation" "CAB034154: AB_2190373, HPA030418: AB_10601602" "unprognostic (1.44e-2)" "unprognostic (2.93e-2)" "unprognostic (2.12e-1)" "prognostic favorable (9.22e-5)" "unprognostic (1.59e-2)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (7.99e-2)" "unprognostic (5.94e-2)" "unprognostic (1.86e-2)" "unprognostic (2.16e-1)" "unprognostic (4.08e-2)" "unprognostic (7.94e-2)" "prognostic favorable (3.43e-5)" "unprognostic (1.61e-2)" SLC37A2 "FLJ00171, SPX2" ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 56.8;Kupffer cells: 38.9;Macrophages: 29.6;Serous glandular cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.3" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 45.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" SLC37A4 "G6PT, G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, SPX4" ENSG00000137700 "Solute carrier family 37 member 4" 11 119023751-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 175.5;Hepatocytes: 152.1;Proximal enterocytes: 263.6;Proximal tubular cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 368.3;Cardiomyocytes: 304.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 26 "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" SLC38A10 "MGC15523, PP1744" ENSG00000157637 "Solute carrier family 38 member 10" Q9HBR0 17 81244811-81295547 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021374, HPA023161, HPA024631" Enhanced Enhanced "Golgi apparatus" NA NA 70000000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "HPA021374: AB_1853858, HPA023161: AB_2190402, HPA024631: AB_1853860" "unprognostic (2.18e-2)" "unprognostic (1.54e-1)" "unprognostic (7.40e-2)" "unprognostic (3.00e-3)" "unprognostic (2.06e-2)" "unprognostic (1.69e-1)" "unprognostic (2.12e-1)" "unprognostic (2.63e-1)" "unprognostic (1.84e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.92e-4)" "unprognostic (8.39e-2)" "prognostic unfavorable (5.34e-7)" "unprognostic (6.55e-2)" "unprognostic (3.15e-1)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" SLC38A11 "AVT2, FLJ39822" ENSG00000169507 "Solute carrier family 38 member 11" Q08AI6 2 164894354-164955525 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.1;epididymis: 31.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.4;Enteroendocrine cells: 135.5;Excitatory neurons: 51.7;granulocytes: 41.0;Sertoli cells: 29.9;Smooth muscle cells: 24.6" "Cancer enriched" "Detected in many" 5 "prostate cancer: 7.6" "Group enriched" "Detected in all" 5 "cerebral cortex: 16.5;choroid plexus: 50.8" "Group enriched" "Detected in some" 27 "memory B-cell: 1.6;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 38 "B-cells: 3.8" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 10.1" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043432 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA043432: AB_10793948" "unprognostic (1.52e-1)" "unprognostic (2.59e-1)" "unprognostic (4.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (6.28e-3)" "unprognostic (3.53e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-3)" "unprognostic (1.99e-1)" "prognostic favorable (2.00e-8)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (2.43e-2)" "unprognostic (2.36e-2)" SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 837.6;Suprabasal keratinocytes: 705.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" SLC38A3 "G17, SN1" ENSG00000188338 "Solute carrier family 38 member 3" Q99624 3 50205246-50221486 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Ion transport, Sodium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 321.4;retina: 167.5" "Group enriched" "Detected in many" 5 "Bipolar cells: 83.9;Cone photoreceptor cells: 144.4;Hepatocytes: 90.4;Muller glia cells: 67.7;Rod photoreceptor cells: 108.9" "Cancer enriched" "Detected in many" 9 "liver cancer: 140.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "liver cancer: 7.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031871 Approved Microtubules,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol Microtubules "HPA031871: AB_2674080" "unprognostic (2.14e-1)" "unprognostic (2.10e-1)" "unprognostic (8.60e-2)" "unprognostic (6.19e-4)" "unprognostic (7.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.34e-2)" "unprognostic (2.30e-2)" "unprognostic (4.68e-3)" "unprognostic (1.46e-1)" "unprognostic (2.06e-1)" "unprognostic (5.71e-2)" "unprognostic (1.23e-3)" "unprognostic (1.90e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.96e-1)" SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 229.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 176.7;Erythroid cells: 51.8;Exocrine glandular cells: 64.7;Plasma cells: 84.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 246.7" "Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Pancreas - Proteolysis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Respiratory epithelial cells - Unknown function" "Vesicles, Plasma membrane" Cytosol "HPA047411: AB_10964355" "unprognostic (2.81e-1)" "unprognostic (4.87e-2)" "unprognostic (7.92e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-3)" "unprognostic (1.26e-1)" "unprognostic (7.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.13e-4)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.27e-3)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.20e-1)" SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61114316 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 213.7;Excitatory neurons: 95.5;Hofbauer cells: 91.0;Inhibitory neurons: 74.3;Late spermatids: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Thyroid gland - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 34: Neurons - Neuronal signaling" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.9" "Cell type enriched" "Detected in all" 5 "Late spermatids: 802.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 36: Late spermatids - Unknown function" 43 "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (2.16e-3)" "unprognostic (2.30e-2)" "unprognostic (6.23e-3)" "prognostic favorable (6.87e-4)" "unprognostic (3.49e-1)" "unprognostic (8.08e-3)" "unprognostic (9.76e-3)" "unprognostic (6.34e-3)" "unprognostic (1.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "prognostic favorable (2.87e-4)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.50e-2)" "unprognostic (4.93e-3)" SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 55.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 177.8;Early spermatids: 285.7;Late spermatids: 102.3;Syncytiotrophoblasts: 601.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 8 Vesicles "HPA043785: AB_10961859, HPA061702: " "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.49e-1)" "unprognostic (8.19e-2)" "unprognostic (8.35e-2)" "unprognostic (7.95e-2)" "unprognostic (5.47e-2)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.87e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-1)" SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.6;thyroid gland: 47.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 165.1;Microglial cells: 346.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 194.8;Excitatory neurons: 104.1;Intestinal goblet cells: 82.2;Oligodendrocytes: 335.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Stomach - Proteolysis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoplasm "HPA021455: AB_2670710" "unprognostic (2.29e-2)" "unprognostic (2.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (2.30e-1)" "unprognostic (1.57e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "unprognostic (3.85e-2)" SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 939.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 4 "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 537.7;pancreas: 245.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 255.4;Hepatocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;seminal vesicle: 32.1;skin 1: 36.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 40.9;Muller glia cells: 23.4;Serous glandular cells: 7.0;Squamous epithelial cells: 13.8;Suprabasal keratinocytes: 25.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.2;head and neck cancer: 2.5" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" 45 "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" SLC39A3 ZIP3 ENSG00000141873 "Solute carrier family 39 member 3" Q9BRY0 19 2732204-2740028 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.6" "Group enriched" "Detected in all" 4 "Early spermatids: 298.7;Late spermatids: 424.1;Spermatocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA042139, HPA058526" Uncertain Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Vesicles "HPA042139: AB_10793875, HPA058526: AB_2683743" "unprognostic (1.81e-1)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "prognostic favorable (9.76e-5)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (9.88e-3)" "unprognostic (1.01e-1)" "unprognostic (6.03e-2)" "unprognostic (3.66e-2)" "unprognostic (4.37e-3)" "unprognostic (4.07e-2)" "unprognostic (1.75e-3)" "unprognostic (9.22e-3)" "unprognostic (6.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.80e-2)" SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 230.5;kidney: 105.8;liver: 167.0;pancreas: 297.9" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 802.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 20.4;Gastric cancer: 12.0;liver cancer: 22.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 272.5;Prostatic glandular cells: 438.2" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" SLC39A7 "D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7" ENSG00000112473 "Solute carrier family 39 member 7" Q92504 6 33200305-33204439 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053999 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 24 "Endoplasmic reticulum" Nucleoplasm "HPA053999: AB_2682338" "unprognostic (3.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (3.24e-2)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (4.87e-2)" "unprognostic (9.92e-2)" "unprognostic (7.20e-3)" "unprognostic (3.29e-1)" "unprognostic (2.40e-1)" "unprognostic (1.99e-2)" "unprognostic (4.80e-1)" "unprognostic (1.50e-1)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" SLC39A8 BIGM103 ENSG00000138821 "Solute carrier family 39 member 8" Q9C0K1 4 102251080-102431258 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport, Zinc transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 67.8" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 735.2;Alveolar cells type 2: 629.7;Extravillous trophoblasts: 241.4;Mesothelial cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038832, HPA038833" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Alveolar cells - Lung function" "HPA038832: AB_2676226, HPA038833: AB_10670910" "prognostic favorable (6.69e-4)" "unprognostic (1.29e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (6.50e-2)" "unprognostic (9.59e-2)" "unprognostic (6.07e-2)" "unprognostic (2.74e-1)" "unprognostic (1.20e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-3)" "unprognostic (2.78e-2)" "prognostic favorable (6.34e-6)" "unprognostic (3.25e-1)" "unprognostic (6.54e-2)" "unprognostic (6.40e-2)" "unprognostic (7.13e-3)" SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 75: Serous glandular cells - Salivary secretion" 30 "Endoplasmic reticulum" "HPA007921: AB_1080007, HPA075390: AB_2686748" "unprognostic (2.37e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (4.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 132.3;kidney: 624.8;pancreas: 210.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Glandular and luminal cells: 95.7;Oocytes: 164.7;Proximal enterocytes: 219.5;Proximal tubular cells: 221.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 15.1;Kidney cancer: 17.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 944.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 458.6;Kupffer cells: 901.1;Syncytiotrophoblasts: 2742.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 327.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 75.6;liver cancer: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: AB_2685524" "unprognostic (1.28e-2)" "unprognostic (1.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.83e-2)" "unprognostic (8.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.66e-1)" "unprognostic (6.22e-2)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "unprognostic (6.43e-2)" "unprognostic (6.44e-2)" "prognostic favorable (8.55e-5)" "unprognostic (4.66e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.11e-2)" SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 95.9;pancreas: 59.7;tongue: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 26 Mitochondria "HPA014721: , HPA015138: AB_1857160" "unprognostic (1.18e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.77e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (5.23e-2)" "unprognostic (5.53e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (4.46e-2)" "unprognostic (3.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" SLC41A2 DKFZP434K0427 ENSG00000136052 "Solute carrier family 41 member 2" Q96JW4 12 104801801-104958744 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 89.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 97.1;Inhibitory neurons: 89.8;Oligodendrocyte precursor cells: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "myeloid DC: 3.1;plasmacytoid DC: 9.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 9.1" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038658 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 83: Liver - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 28 "HPA038658: AB_10671747" "unprognostic (7.19e-2)" "unprognostic (4.38e-3)" "unprognostic (1.94e-2)" "unprognostic (2.38e-1)" "unprognostic (6.06e-3)" "unprognostic (3.05e-2)" "prognostic favorable (9.94e-4)" "unprognostic (1.35e-1)" "unprognostic (3.68e-1)" "unprognostic (3.65e-1)" "unprognostic (4.20e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-2)" "unprognostic (5.30e-2)" SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 6: Ovarian stromal cells - Transcription" 9 "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 125.5;pancreas: 225.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.4;Erythroid cells: 49.2;Exocrine glandular cells: 34.2;Hepatocytes: 104.9" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 1: Erythroid cells - Oxygen transport" 1 "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" SLC43A2 MGC34680 ENSG00000167703 "Solute carrier family 43 member 2" Q8N370 17 1569268-1628886 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.4" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 378.6;monocytes: 249.8;Syncytiotrophoblasts: 932.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021564 Enhanced NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 5 "HPA021564: AB_1857169" "unprognostic (5.95e-3)" "unprognostic (4.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.42e-2)" "unprognostic (2.58e-2)" "unprognostic (2.80e-2)" "unprognostic (1.05e-2)" "unprognostic (5.02e-2)" "unprognostic (6.49e-2)" "unprognostic (2.80e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.96e-1)" "prognostic favorable (5.40e-5)" "unprognostic (1.84e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-1)" "unprognostic (2.20e-1)" SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 143.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.6;Ductal cells: 69.8;Hofbauer cells: 73.1;Langerhans cells: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.9;intermediate monocyte: 127.2;myeloid DC: 85.9;non-classical monocyte: 147.3;plasmacytoid DC: 86.0" "Group enriched" "Detected in all" 4 "dendritic cells: 86.0;monocytes: 147.3" "Cancer enhanced" "Detected in many" "skin cancer: 220.6" "Colon - Endothelial cells" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" SLC44A1 "CD92, CDW92, CHTL1, CTL1" ENSG00000070214 "Solute carrier family 44 member 1" Q8WWI5 9 105244622-105439171 "CD markers, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 232.8" "Cell type enriched" "Detected in all" 8 "Oligodendrocytes: 2274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064714, HPA074007" Enhanced Supported Nucleoplasm,Mitochondria NA NA 99000 "Cluster 14: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" Mitochondria Nucleoplasm "HPA064714: AB_2685334, HPA074007: " "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.54e-3)" "unprognostic (4.77e-2)" "unprognostic (1.74e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.49e-4)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.64e-3)" "unprognostic (6.20e-2)" "prognostic favorable (1.85e-4)" "unprognostic (2.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-2)" SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 172.8;Extravillous trophoblasts: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" SLC44A3 "CTL3, MGC45474" ENSG00000143036 "Solute carrier family 44 member 3" Q8N4M1 1 94820342-94895246 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 49.1;Undifferentiated cells: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 18 "T-cells: 1.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 50.1" "Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in all" HPA047433 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "HPA047433: AB_2680046" "unprognostic (8.06e-2)" "unprognostic (7.65e-2)" "unprognostic (4.63e-3)" "unprognostic (3.57e-2)" "unprognostic (1.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.14e-1)" "unprognostic (4.03e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (5.78e-2)" "unprognostic (2.44e-2)" "prognostic favorable (7.63e-5)" "unprognostic (9.09e-2)" "unprognostic (8.28e-2)" "unprognostic (5.95e-2)" "unprognostic (3.31e-3)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 128.3;prostate: 80.5;stomach 1: 81.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 304.9;Club cells: 219.1;Distal enterocytes: 526.0;Gastric mucus-secreting cells: 189.2;Intestinal goblet cells: 253.6;Ionocytes: 213.9;Paneth cells: 184.9;Prostatic glandular cells: 320.8;Proximal enterocytes: 256.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.7;Gastric cancer: 10.1;prostate cancer: 27.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC44A5 "CTL5, MGC34032" ENSG00000137968 "Solute carrier family 44 member 5" Q8NCS7 1 75202129-75611114 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 10.4" "Cell type enhanced" "Detected in many" "Early spermatids: 102.2;Excitatory neurons: 264.8;Inhibitory neurons: 540.1;Oligodendrocyte precursor cells: 249.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047455, HPA051011" Uncertain Approved Cytosol NA NA "Cluster 21: Testis - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" 8 Cytosol "HPA047455: AB_2680054, HPA051011: AB_2681309" "unprognostic (9.00e-2)" "unprognostic (1.91e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-3)" "unprognostic (4.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (5.78e-3)" "unprognostic (6.41e-2)" "unprognostic (9.19e-2)" "prognostic unfavorable (6.52e-4)" "unprognostic (1.70e-3)" "unprognostic (1.47e-1)" "unprognostic (2.68e-2)" "unprognostic (4.30e-1)" SLC45A1 DNB5 ENSG00000162426 "Solute carrier family 45 member 1" Q9Y2W3 1 8318114-8344167 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Symport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.2;Cone photoreceptor cells: 8.5;Excitatory neurons: 9.7;Horizontal cells: 13.2;Inhibitory neurons: 10.6" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 5 "monocytes: 4.0" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 9.6" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078818 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA078818: " "unprognostic (1.77e-3)" "unprognostic (1.37e-2)" "unprognostic (4.32e-3)" "unprognostic (8.32e-2)" "unprognostic (3.22e-3)" "unprognostic (1.56e-1)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (1.39e-3)" "unprognostic (3.18e-1)" "unprognostic (5.67e-2)" "unprognostic (8.53e-3)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (2.51e-3)" SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" "Symport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "prostate: 296.4" "Group enriched" "Detected in many" 6 "granulocytes: 113.6;Prostatic glandular cells: 431.1" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.6" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.6" "Cancer enriched" "Detected in all" 7 "prostate cancer: 115.8" "Breast - Breast myoepithelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Neuronal - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Prostatic glandular cells - Transcription" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 38.9;Cone photoreceptor cells: 44.2;Gastric mucus-secreting cells: 41.3;Glandular and luminal cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" SLC46A1 "HCP1, hPCFT, HsPCFT, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 91.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.3;Hepatocytes: 26.0;Hofbauer cells: 22.9;Kupffer cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 15.9;lung: 10.1;lymphoid tissue: 15.6;skin 1: 23.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 25.2;Ciliated cells: 4.1;Club cells: 4.5;Glandular and luminal cells: 6.4;Hofbauer cells: 5.1;Kupffer cells: 8.4;Late spermatids: 5.2;Macrophages: 4.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.7;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.7" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 72: Alveolar cells - Lung function" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 73.9;liver: 93.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 48.5;Proximal enterocytes: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 123.4;kidney: 96.7;liver: 100.6" "Cell type enhanced" "Detected in many" "Early spermatids: 17.9;Hepatocytes: 36.9;Inhibitory neurons: 13.8;Proximal tubular cells: 38.7;Skeletal myocytes: 30.2" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 130.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Erythroid cells - Oxygen transport" 6 Vesicles "HPA065396: , HPA073994: " "unprognostic (9.60e-2)" "prognostic favorable (4.27e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (9.88e-2)" "unprognostic (1.54e-2)" "unprognostic (6.63e-3)" "prognostic favorable (1.34e-6)" "unprognostic (1.45e-1)" "unprognostic (5.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 36.8;Extravillous trophoblasts: 39.0;Hofbauer cells: 34.2;Late spermatids: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043593 Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" SLC49A4 "DIRC2, FLJ14784, RCC4" ENSG00000138463 "Solute carrier family 49 member 4" Q96SL1 3 122795069-122881139 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.4;monocytes: 86.7;Syncytiotrophoblasts: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072579 Supported Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Vesicles "HPA072579: AB_2686536" "unprognostic (1.40e-1)" "unprognostic (8.53e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (9.74e-2)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.87e-1)" "prognostic favorable (8.81e-11)" "unprognostic (2.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (7.13e-2)" SLC4A1 "AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR" ENSG00000004939 "Solute carrier family 4 member 1 (Diego blood group)" P02730 17 44248390-44268141 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Blood group antigen" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "bone marrow: 397.2" "Cell type enriched" "Detected in some" 290 "Erythroid cells: 891.7" "Cancer enriched" "Detected in single" 91 "renal cancer: 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 62 "Leukemia: 15.2" "Kidney - Intercalated cells, Liver - Erythroid cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015584, CAB034438, HPA063911" Enhanced NA NA 22000000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 8 "CAB034438: AB_2123479, HPA015584: AB_1844824, HPA063911: AB_2685151" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-2)" "unprognostic (2.32e-2)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (6.72e-3)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (1.93e-2)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (2.13e-1)" SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 33.7;choroid plexus: 55.6;retina: 33.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 584.1;Inhibitory neurons: 538.5" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Region enhanced" "Detected in all" "choroid plexus: 311.0" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.4" "Lineage enriched" "Detected in single" 65 "T-cells: 63.4" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Adipose visceral - T-cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" "HPA034755: AB_10670296, HPA076725: " "unprognostic (4.64e-4)" "unprognostic (3.88e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "unprognostic (7.89e-3)" "unprognostic (5.99e-4)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" "unprognostic (5.65e-2)" "unprognostic (9.23e-3)" "unprognostic (1.87e-1)" "unprognostic (2.10e-3)" "unprognostic (2.26e-1)" SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.8;salivary gland: 52.4;thyroid gland: 59.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 28.7;Club cells: 28.2;Collecting duct cells: 101.1;Ionocytes: 67.0;Salivary duct cells: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 272.4" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 93.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 13 "choroid plexus: 1044.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 72: Alveolar cells - Lung function" "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: AB_1844825" "unprognostic (1.19e-1)" "unprognostic (3.33e-3)" "unprognostic (8.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.04e-6)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (3.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.26e-4)" "unprognostic (4.67e-3)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-2)" SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 274.0;ovary: 120.2" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 174.1;Horizontal cells: 136.0" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 53 "dendritic cells: 5.8" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Nucleoplasm "HPA063498: AB_2685025" "unprognostic (9.49e-2)" "unprognostic (5.72e-3)" "unprognostic (8.92e-4)" "unprognostic (1.77e-2)" "unprognostic (6.61e-3)" "unprognostic (1.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (8.15e-3)" "unprognostic (1.97e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.12e-4)" SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 115.3;pancreas: 252.0" "Cell type enhanced" "Detected in many" "Astrocytes: 776.9;Cholangiocytes: 141.2;Distal enterocytes: 266.3;Ductal cells: 152.5;Prostatic glandular cells: 126.3;Proximal tubular cells: 173.2" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.0;prostate cancer: 13.6" "Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" 1 "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" SLC4A5 NBC4 ENSG00000188687 "Solute carrier family 4 member 5" Q9BY07 2 74216242-74343416 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Sodium transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 42.7;parathyroid gland: 11.8;retina: 40.6;testis: 15.4;thyroid gland: 25.9" "Cell type enhanced" "Detected in many" "Astrocytes: 15.2;Bipolar cells: 22.4;Cone photoreceptor cells: 20.4;Horizontal cells: 41.5;Oligodendrocytes: 28.9;Rod photoreceptor cells: 45.5" "Cancer enriched" "Detected in single" 11 "thyroid cancer: 3.3" "Region enriched" "Detected in all" 5 "choroid plexus: 161.3" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Group enriched" "Detected in many" 5 "basal ganglia: 1.6;hippocampal formation: 5.2;pons and medulla: 6.5;thalamus: 3.5" "Low region specificity" "Detected in all" HPA036621 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA036621: AB_10696779" "unprognostic (1.30e-1)" "unprognostic (3.78e-2)" "unprognostic (2.75e-2)" "unprognostic (1.83e-4)" "unprognostic (3.38e-1)" "unprognostic (2.36e-2)" "unprognostic (2.56e-3)" "unprognostic (5.37e-4)" "unprognostic (1.39e-1)" "unprognostic (2.55e-1)" "unprognostic (1.55e-3)" "unprognostic (3.24e-2)" "unprognostic (1.72e-5)" "unprognostic (1.57e-1)" "unprognostic (1.06e-2)" "unprognostic (8.47e-2)" "unprognostic (9.27e-4)" SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 55.4;retina: 70.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 470.7;Rod photoreceptor cells: 699.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 66: Photoreceptor cells - Visual perception" 3 "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: AB_10795135" "unprognostic (2.94e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-3)" "unprognostic (1.91e-1)" "unprognostic (8.48e-3)" "unprognostic (2.68e-1)" "unprognostic (6.79e-4)" "unprognostic (4.13e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-3)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" SLC4A8 NBC3 ENSG00000050438 "Solute carrier family 4 member 8" Q2Y0W8 12 51391317-51515763 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.6;pituitary gland: 17.4;retina: 10.8;testis: 11.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.2;Cone photoreceptor cells: 62.9;Early spermatids: 56.8;Excitatory neurons: 111.0;Horizontal cells: 107.0;Inhibitory neurons: 122.7;Oligodendrocytes: 231.8;Spermatocytes: 86.3" "Group enriched" "Detected in some" 6 "breast cancer: 1.7;glioma: 2.7;testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.4" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077895 Approved "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA077895: " "unprognostic (4.01e-1)" "unprognostic (8.15e-2)" "unprognostic (2.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.96e-2)" "unprognostic (3.46e-2)" "unprognostic (7.72e-4)" "unprognostic (3.13e-2)" "unprognostic (7.03e-3)" "unprognostic (1.07e-4)" "unprognostic (1.70e-1)" "unprognostic (9.60e-6)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 48 "kidney: 34.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Distal tubular cells: 3.1;Excitatory neurons: 2.3;Inhibitory neurons: 2.3;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 6.0;Spermatocytes: 1.7" "Cancer enriched" "Detected in single" 8 "renal cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Kidney - Intercalated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane, Cytosol" Vesicles "HPA051307: AB_2681434" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-2)" "unprognostic (3.28e-3)" "unprognostic (2.78e-1)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (1.82e-2)" SLC50A1 "HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1" ENSG00000169241 "Solute carrier family 50 member 1" Q9BRV3 1 155135344-155138857 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 149.0;Intestinal goblet cells: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018095 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Breast glandular cells - Lactation" 3 "HPA018095: AB_1856048" "unprognostic (4.75e-2)" "unprognostic (1.21e-1)" "unprognostic (7.57e-2)" "unprognostic (2.24e-1)" "unprognostic (3.29e-1)" "unprognostic (9.30e-2)" "unprognostic (1.64e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (5.51e-2)" "unprognostic (3.53e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (4.36e-2)" "unprognostic (1.40e-1)" "unprognostic (3.50e-3)" "unprognostic (4.39e-2)" SLC51A OSTalpha ENSG00000163959 "Solute carrier family 51 subunit alpha" Q86UW1 3 196211487-196243178 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 62.7;liver: 69.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.0;Leydig cells: 62.4;Peritubular cells: 102.4;Proximal enterocytes: 314.1;Sertoli cells: 62.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045488 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 5: Enterocytes - Absorption" 2 "HPA045488: " "unprognostic (1.63e-2)" "unprognostic (1.27e-3)" "unprognostic (2.80e-1)" "unprognostic (7.66e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.54e-4)" "unprognostic (5.02e-2)" "unprognostic (1.07e-1)" "unprognostic (5.98e-3)" "unprognostic (5.41e-2)" "unprognostic (2.90e-2)" "unprognostic (2.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-5)" SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 40.3;intestine: 104.1" "Group enriched" "Detected in some" 9 "Distal enterocytes: 402.9;Proximal enterocytes: 788.7" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.7" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 2 Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" SLC52A2 "D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2" ENSG00000185803 "Solute carrier family 52 member 2" Q9HAB3 8 144333957-144361286 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Host cell receptor for virus entry, Receptor" "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA063036 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 2 "HPA063036: AB_2684928" "unprognostic (7.80e-3)" "prognostic unfavorable (7.55e-4)" "unprognostic (2.15e-1)" "unprognostic (2.94e-1)" "unprognostic (3.09e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (7.74e-3)" "unprognostic (9.20e-2)" "unprognostic (2.24e-2)" "unprognostic (4.85e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.12e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;testis: 39.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 21.4;Cytotrophoblasts: 32.7;Glandular and luminal cells: 22.4;Proximal enterocytes: 41.6;Syncytiotrophoblasts: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA049391: AB_2680743, HPA059078: AB_2732630" "unprognostic (4.53e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (9.03e-3)" "unprognostic (2.12e-3)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (4.36e-2)" "unprognostic (4.39e-3)" "unprognostic (4.82e-2)" "unprognostic (2.04e-3)" "prognostic favorable (5.51e-6)" "unprognostic (3.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 513.5" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 749.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 8.3;Gastric cancer: 2.7" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Cholangiocyte, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Uncertain "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nuclear membrane, Golgi apparatus" "Nucleoplasm, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" SLC5A10 SGLT5 ENSG00000154025 "Solute carrier family 5 member 10" A0PJK1 17 18950345-19022595 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 40.1" "Group enriched" "Detected in some" 4 "Late spermatids: 33.3;Proximal tubular cells: 50.4" "Cancer enriched" "Detected in some" 11 "renal cancer: 6.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.8;non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 7 "monocytes: 4.9" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052014 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA052014: AB_2681694" "unprognostic (3.74e-1)" "unprognostic (2.92e-1)" "unprognostic (3.04e-2)" "unprognostic (6.11e-2)" "unprognostic (6.56e-2)" "unprognostic (3.36e-4)" "unprognostic (7.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.52e-1)" "unprognostic (8.94e-2)" "unprognostic (3.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-2)" "unprognostic (3.43e-2)" "unprognostic (2.61e-2)" "unprognostic (2.75e-2)" "unprognostic (2.11e-1)" SLC5A11 "KST1, SGLT6, SMIT2" ENSG00000158865 "Solute carrier family 5 member 11" Q8WWX8 16 24845841-24911628 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 56.1" "Cell type enriched" "Detected in some" 18 "Oligodendrocytes: 631.0" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.2" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035331 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 50: Lymphoma - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm Cytosol "HPA035331: AB_10601489" "unprognostic (2.57e-1)" "unprognostic (7.90e-3)" "unprognostic (1.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.90e-2)" "unprognostic (8.08e-2)" "unprognostic (2.85e-1)" "unprognostic (2.85e-3)" "unprognostic (6.68e-2)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (1.45e-3)" SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 46.6;intestine: 29.2;kidney: 165.6" "Group enriched" "Detected in some" 31 "Proximal enterocytes: 247.1;Proximal tubular cells: 149.7" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" SLC5A2 SGLT2 ENSG00000140675 "Solute carrier family 5 member 2" P31639 16 31483002-31490860 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "kidney: 52.7" "Group enriched" "Detected in some" 4 "Early spermatids: 58.4;Late spermatids: 142.5;Proximal tubular cells: 113.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041603 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA041603: AB_10960540" "unprognostic (1.61e-1)" "unprognostic (2.95e-1)" "unprognostic (2.84e-1)" "unprognostic (3.00e-2)" "unprognostic (8.04e-2)" "unprognostic (8.23e-3)" "unprognostic (1.49e-1)" "unprognostic (2.25e-3)" "unprognostic (2.57e-1)" "unprognostic (1.12e-2)" "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (1.42e-3)" "unprognostic (5.88e-2)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (3.22e-1)" SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 28.0;thyroid gland: 24.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 124.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.3" "Region enriched" "Detected in all" 4 "choroid plexus: 208.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Non-specific - Transcription" "Plasma membrane" "HPA029791: AB_10601892" "unprognostic (9.70e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (4.48e-3)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" SLC5A5 NIS ENSG00000105641 "Solute carrier family 5 member 5" Q92911 19 17871945-17895174 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 138.0;salivary gland: 62.6;stomach 1: 57.3" "Cell type enriched" "Detected in some" 38 "Gastric mucus-secreting cells: 217.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.7" "Region enriched" "Detected in all" 15 "choroid plexus: 351.6" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022364, HPA049055" Enhanced NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" 2 "CAB022364: , HPA049055: AB_2680614" "unprognostic (2.72e-2)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (4.02e-2)" "unprognostic (2.57e-1)" "unprognostic (1.94e-2)" "unprognostic (3.07e-1)" "unprognostic (2.01e-2)" "unprognostic (3.03e-1)" "unprognostic (3.93e-2)" "unprognostic (5.51e-8)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-2)" "unprognostic (3.23e-1)" SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 101.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 121.1;Extravillous trophoblasts: 107.2;Syncytiotrophoblasts: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 34: Testis cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" SLC5A7 "CHT1, hCHT" ENSG00000115665 "Solute carrier family 5 member 7" Q9GZV3 2 107986523-108013994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter biosynthesis, Sodium transport, Symport, Transport" "Congenital myasthenic syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;intestine: 2.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 2.3;Bipolar cells: 1.5;Club cells: 1.6;Melanocytes: 1.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Region enhanced" "Detected in many" "pons: 72.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Neuroblastoma: 4.3" "Colon - Enteric glia cells" "Group enriched" "Detected in many" 4 "basal ganglia: 23.1;hypothalamus: 9.0;midbrain: 9.4;pons and medulla: 14.4;thalamus: 6.2" "Group enriched" "Detected in many" 6 "basal ganglia: 28.3;pons: 36.6;spinal cord: 64.7" HPA046105 Approved "Nuclear bodies,Cell Junctions,Intermediate filaments" NA NA "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Cell Junctions, Intermediate filaments" "Nuclear bodies" "HPA046105: " "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-3)" "unprognostic (7.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-4)" "unprognostic (1.05e-2)" "unprognostic (9.78e-3)" "unprognostic (6.42e-2)" "unprognostic (1.61e-2)" SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 42.1" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 74.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "liver cancer: 3.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 6: Non-specific - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.2;Syncytiotrophoblasts: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 180.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 153.5;Late spermatids: 175.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 28: Dendritic cells - Antigen presentation" 19 Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 136.9" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" SLC6A1 "GABATHG, GABATR, GAT-1, GAT1, hGAT-1" ENSG00000157103 "Solute carrier family 6 member 1" P30531 3 10992186-11039247 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 107.9;liver: 85.4;retina: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.6;Horizontal cells: 151.1;Inhibitory neurons: 317.1;Microglial cells: 103.8;Oligodendrocyte precursor cells: 122.2;Oligodendrocytes: 100.4" "Group enriched" "Detected in some" 16 "glioma: 16.1;liver cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013341, CAB022293" Enhanced NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 65: Neurons - Synaptic function" 2 "CAB022293: , HPA013341: AB_1849509" "unprognostic (1.66e-3)" "unprognostic (1.30e-3)" "unprognostic (4.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.53e-1)" "unprognostic (2.53e-1)" "prognostic favorable (3.20e-4)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (8.26e-2)" "unprognostic (2.90e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (7.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (5.34e-2)" SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 80.8" "Cell type enhanced" "Detected in some" "Astrocytes: 80.8;Excitatory neurons: 13.3;Horizontal cells: 20.8;Inhibitory neurons: 24.5;Muller glia cells: 22.6;Oligodendrocyte precursor cells: 21.7" "Cancer enhanced" "Detected in many" "glioma: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 7.2" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" Nucleoplasm Vesicles "HPA037981: AB_10671383" "unprognostic (6.04e-2)" "unprognostic (8.01e-2)" "unprognostic (1.21e-7)" "unprognostic (8.60e-2)" "unprognostic (8.68e-2)" "unprognostic (9.72e-3)" "unprognostic (6.39e-3)" "unprognostic (9.77e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-3)" "unprognostic (6.06e-2)" "unprognostic (4.44e-2)" "unprognostic (9.83e-2)" "unprognostic (2.31e-2)" SLC6A12 BGT-1 ENSG00000111181 "Solute carrier family 6 member 12" P48065 12 190077-214570 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 30.8;kidney: 35.0;liver: 70.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 37.0;Glandular and luminal cells: 8.4;Hepatocytes: 18.4;Oligodendrocytes: 8.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.8;renal cancer: 11.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 43 "classical monocyte: 4.9;intermediate monocyte: 4.8;myeloid DC: 2.1;neutrophil: 2.6;non-classical monocyte: 7.0" "Group enriched" "Detected in many" 40 "dendritic cells: 2.1;granulocytes: 2.6;monocytes: 7.0" "Group enriched" "Detected in some" 5 "liver cancer: 1.9;ovarian cancer: 4.2;testis cancer: 2.5;thyroid cancer: 2.3;Uterine cancer: 4.3" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034973 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 Vesicles "HPA034973: AB_10610427" "unprognostic (3.48e-1)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-2)" "unprognostic (8.30e-2)" "unprognostic (6.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.85e-2)" "unprognostic (3.68e-1)" "prognostic favorable (2.70e-6)" "unprognostic (2.30e-1)" "unprognostic (4.92e-4)" "unprognostic (3.35e-1)" "unprognostic (4.31e-4)" SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 147.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 245.5" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.6;salivary gland: 20.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 193.3;Basal respiratory cells: 110.0;Club cells: 166.6;Ionocytes: 275.7;Mucus glandular cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 10.1" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" HPA003193 Uncertain Approved Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA003193: AB_2190122" "unprognostic (3.06e-2)" "unprognostic (3.55e-2)" "unprognostic (8.49e-2)" "unprognostic (1.00e-3)" "unprognostic (1.30e-3)" "unprognostic (1.49e-2)" "unprognostic (7.41e-3)" "unprognostic (3.67e-3)" "unprognostic (2.66e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" SLC6A15 "FLJ10316, hv7-3, NTT73, SBAT1, V7-3" ENSG00000072041 "Solute carrier family 6 member 15" Q9H2J7 12 84859491-84913629 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.6;retina: 15.2" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 27.3;Bipolar cells: 35.0;Excitatory neurons: 61.7;Horizontal cells: 39.0;Inhibitory neurons: 54.9;Melanocytes: 73.9;Oligodendrocytes: 43.6;Rod photoreceptor cells: 28.1" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.2;melanoma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 38.9;skin cancer: 33.3" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008609 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 5 Nucleoli Vesicles "HPA008609: AB_1857190" "unprognostic (1.01e-4)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (6.65e-6)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "unprognostic (7.65e-3)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (7.69e-4)" "unprognostic (2.57e-2)" "unprognostic (3.80e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-3)" SLC6A16 NTT5 ENSG00000063127 "Solute carrier family 6 member 16" Q9GZN6 19 49289638-49325215 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 91.4" "Group enriched" "Detected in many" 7 "Early spermatids: 150.7;Late spermatids: 48.1;Spermatocytes: 126.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.1" "Testis - Early spermatids" "Not detected" "Not detected" HPA076812 Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Golgi apparatus" "HPA076812: AB_2686816" "unprognostic (1.98e-1)" "unprognostic (7.15e-3)" "unprognostic (6.39e-3)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.83e-3)" "unprognostic (7.89e-2)" "unprognostic (7.92e-2)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-3)" "unprognostic (1.63e-1)" "unprognostic (3.23e-2)" "unprognostic (3.31e-1)" "unprognostic (2.10e-1)" "unprognostic (8.93e-2)" "unprognostic (4.18e-2)" SLC6A17 NTT4 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 55.7;pituitary gland: 24.6" "Group enriched" "Detected in some" 9 "Excitatory neurons: 58.6;Horizontal cells: 29.6;Inhibitory neurons: 56.9;Melanocytes: 41.2" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.9" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 69: Neurons - Neuronal signaling" 1 Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" SLC6A18 "FLJ31236, Xtrp2" ENSG00000164363 "Solute carrier family 6 member 18" Q96N87 5 1225381-1246189 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 75 "kidney: 7.9" "Cell type enriched" "Detected in some" 16 "Proximal tubular cells: 32.2" "Cancer enriched" "Detected in single" 44 "renal cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA011885 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA011885: AB_1857198" "unprognostic (2.02e-1)" "unprognostic (5.69e-3)" "unprognostic (2.90e-1)" SLC6A19 B0AT1 ENSG00000174358 "Solute carrier family 6 member 19" Q695T7 5 1201595-1225111 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "intestine: 138.5;kidney: 85.6" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 513.6" "Group enriched" "Detected in many" 4 "renal cancer: 7.9;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 6.1;liver cancer: 7.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037415, HPA043207" Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA037415: AB_10672346, HPA043207: AB_2678363" "unprognostic (1.26e-1)" "unprognostic (1.01e-3)" "unprognostic (6.04e-2)" "unprognostic (3.64e-1)" "prognostic favorable (4.14e-6)" "unprognostic (1.37e-1)" "unprognostic (7.36e-2)" SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655988-55707645 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.1;placenta: 6.6;skin 1: 4.5;testis: 4.3" "Group enriched" "Detected in some" 6 "Early spermatids: 4.0;Extravillous trophoblasts: 9.4;Late spermatids: 4.7;Spermatocytes: 8.3;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.9" "Region enriched" "Detected in some" 35 "pons: 192.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 50 "Neuroblastoma: 54.0" "Kidney - Intercalated cells, Testis - Early spermatids" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 17.9" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 21: Testis - Unknown function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Cytosol Mitochondria "CAB078195: AB_2665806, HPA004057: AB_1080012, HPA076311: AB_2732307" "unprognostic (9.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.26e-4)" "unprognostic (4.07e-1)" "unprognostic (4.16e-1)" "unprognostic (8.38e-2)" "unprognostic (2.97e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.95e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (8.48e-2)" "unprognostic (1.43e-2)" SLC6A3 "DAT, DAT1" ENSG00000142319 "Solute carrier family 6 member 3" Q01959 5 1392794-1445440 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 119 "brain: 95.8" "Cell type enhanced" "Detected in some" "granulocytes: 2.1;Lymphatic endothelial cells: 8.3;Oocytes: 8.8;Serous glandular cells: 2.2" "Cancer enriched" "Detected in some" 18 "renal cancer: 25.7" "Region enriched" "Detected in some" 28 "midbrain: 133.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Kidney cancer: 5.0" "Adipose visceral - Mesothelial cells" "Group enriched" "Detected in many" 8 "midbrain: 80.6;thalamus: 29.0" "Region enriched" "Detected in some" 152 "midbrain: 393.2" "HPA012763, HPA013602, CAB016249, CAB078172" Enhanced Supported Approved Vesicles NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 6 Vesicles "CAB016249: AB_627402, CAB078172: AB_2665810, HPA012763: AB_2732405, HPA013602: AB_1847484" "unprognostic (2.25e-4)" "unprognostic (2.22e-1)" "unprognostic (8.45e-2)" "unprognostic (5.24e-2)" "unprognostic (7.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.64e-5)" "unprognostic (9.31e-2)" "unprognostic (7.89e-2)" "unprognostic (4.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (3.40e-7)" "unprognostic (6.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.22e-2)" "unprognostic (4.74e-2)" SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "intestine: 39.2;lung: 27.9;placenta: 17.8" "Group enriched" "Detected in many" 10 "Cytotrophoblasts: 119.5;Proximal enterocytes: 100.4;Syncytiotrophoblasts: 95.7" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Group enriched" "Detected in many" 11 "midbrain: 507.8;pons: 183.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.5;liver cancer: 1.4" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 8 "midbrain: 51.2;pons: 38.2" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (7.45e-2)" "unprognostic (7.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.72e-4)" "unprognostic (2.07e-1)" "unprognostic (8.42e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-3)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (4.98e-2)" "unprognostic (1.76e-1)" "unprognostic (4.05e-2)" "unprognostic (7.18e-2)" SLC6A5 "GlyT-2, GLYT2, NET1" ENSG00000165970 "Solute carrier family 6 member 5" Q9Y345 11 20599594-20659285 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Late spermatids: 71.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "medulla oblongata: 46.3;pons: 42.5;spinal cord: 15.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.9" "Testis - Late spermatids" "Region enriched" "Detected in some" 9 "pons and medulla: 49.3" "Group enriched" "Detected in many" 8 "medulla oblongata: 37.4;spinal cord: 22.5" CAB079052 Supported NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 63: Late spermatids - Spermatogenesis" "CAB079052: " "unprognostic (6.94e-2)" "unprognostic (2.28e-1)" "unprognostic (4.75e-2)" SLC6A6 TAUT ENSG00000131389 "Solute carrier family 6 member 6" P31641 3 14402576-14489349 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 139.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 458.8;Rod photoreceptor cells: 607.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 56.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015028, HPA016488" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 66: Photoreceptor cells - Visual perception" "Cell Junctions, Cytosol" "HPA015028: AB_1857200, HPA016488: AB_1857202" "unprognostic (8.25e-2)" "unprognostic (7.29e-3)" "unprognostic (2.63e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (5.75e-8)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.58e-1)" "unprognostic (2.56e-1)" "unprognostic (3.81e-1)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-2)" "unprognostic (9.65e-2)" "unprognostic (1.90e-1)" SLC6A7 PROT ENSG00000011083 "Solute carrier family 6 member 7" Q99884 5 150190062-150222788 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 65.6" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 40.2" "Cancer enhanced" "Detected in single" "colorectal cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.8" "Colon - Colon enterocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028907, HPA063773" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA028907: AB_10602404, HPA063773: " "unprognostic (3.01e-1)" "unprognostic (1.97e-2)" "unprognostic (3.70e-2)" "unprognostic (1.42e-3)" "unprognostic (1.09e-2)" "unprognostic (1.82e-4)" "unprognostic (6.42e-2)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (1.33e-1)" "unprognostic (2.55e-1)" "unprognostic (3.50e-1)" "unprognostic (3.73e-4)" "unprognostic (8.11e-2)" "unprognostic (5.46e-2)" "unprognostic (2.73e-1)" "unprognostic (3.70e-3)" SLC6A9 "GlyT-1, GLYT1" ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.3;skin 1: 45.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.0;Distal enterocytes: 20.0;Erythroid cells: 34.7;Horizontal cells: 44.1;Suprabasal keratinocytes: 19.6" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 13: Non-specific - Mixed function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" SLC7A1 "ATRC1, CAT-1, ERR, HCAT1, REC1L" ENSG00000139514 "Solute carrier family 7 member 1" P30825 13 29509414-29595688 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 53.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 227.1;Microglial cells: 154.8;Squamous epithelial cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039721, HPA077838" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 12: Squamous epithelial cells - Keratinization" 47 "HPA039721: AB_10672893, HPA077838: " "unprognostic (1.85e-1)" "unprognostic (1.04e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (1.36e-3)" "unprognostic (2.02e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.20e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (7.37e-3)" SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "adipose tissue: 30.7;brain: 20.0;breast: 12.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 38.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.5;Gastric cancer: 1.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 1 "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Cell type enhanced" "Detected in many" "Astrocytes: 349.6;dendritic cells: 75.1;Gastric mucus-secreting cells: 57.8;Langerhans cells: 69.4;Microglial cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 158.2" "Liver - Vascular Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 4 Vesicles "HPA064215: AB_2685213" "unprognostic (3.55e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-2)" "unprognostic (7.18e-3)" "unprognostic (2.59e-1)" "unprognostic (8.80e-3)" "unprognostic (2.07e-8)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (2.22e-8)" "unprognostic (3.81e-2)" "unprognostic (3.76e-2)" "unprognostic (2.29e-2)" "unprognostic (1.54e-2)" SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.5;pituitary gland: 7.1;retina: 5.9" "Group enriched" "Detected in some" 5 "Bipolar cells: 24.1;Excitatory neurons: 59.8;Horizontal cells: 29.6;Inhibitory neurons: 86.6;Oligodendrocytes: 62.7" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 10.1" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 31 "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 171.5;parathyroid gland: 216.8" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 157.5;Hepatocytes: 202.5;Secretory cells: 133.1;Smooth muscle cells: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.6;testis: 14.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.8;Glandular and luminal cells: 32.0;Intestinal goblet cells: 10.5;Mesothelial cells: 16.9;Prostatic glandular cells: 9.6;Syncytiotrophoblasts: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.6" "Liver - Hepatic stellate cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "HPA031023: AB_10669669" "unprognostic (1.02e-3)" "unprognostic (4.34e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (3.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.58e-2)" "unprognostic (1.21e-3)" "unprognostic (9.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 109.2;esophagus: 97.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 163.8;dendritic cells: 327.8;Plasma cells: 133.2;Syncytiotrophoblasts: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1339.5" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 72.4" "Cell type enhanced" "Detected in many" "Microglial cells: 52.8;Skeletal myocytes: 94.7;Syncytiotrophoblasts: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 117.6;kidney: 261.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 247.6;Kupffer cells: 327.7;Macrophages: 131.4;monocytes: 264.1;Proximal enterocytes: 399.8;Proximal tubular cells: 264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 393.7;non-classical monocyte: 447.3" "Lineage enriched" "Detected in many" 5 "monocytes: 447.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 319.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 98.0;Proximal tubular cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.3;eosinophil: 11.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.8" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 25 "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" SLC7A9 CSNU3 ENSG00000021488 "Solute carrier family 7 member 9" P82251 19 32830509-32869767 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 121.3;kidney: 65.7" "Cell type enriched" "Detected in some" 11 "Proximal enterocytes: 817.9" "Group enriched" "Detected in some" 7 "liver cancer: 6.6;renal cancer: 5.2;stomach cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.4;liver cancer: 3.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA042591 Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "HPA042591: AB_10962500" "unprognostic (4.12e-2)" "unprognostic (5.40e-2)" "unprognostic (6.19e-2)" "unprognostic (3.37e-3)" "unprognostic (1.69e-1)" "unprognostic (1.54e-1)" "unprognostic (4.17e-2)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (9.69e-2)" "unprognostic (5.97e-2)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (5.10e-5)" SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 148.4" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 942.4;Excitatory neurons: 1224.1;Inhibitory neurons: 602.1;Microglial cells: 548.4;Oligodendrocyte precursor cells: 706.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 39.9" "Group enriched" "Detected in many" 6 "granulocytes: 39.9;monocytes: 12.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Intercalated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 2 "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" SLC8A2 "KIAA1087, NCX2" ENSG00000118160 "Solute carrier family 8 member A2" Q9UPR5 19 47428017-47471893 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 100.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.9;Excitatory neurons: 38.9;Horizontal cells: 7.6;Inhibitory neurons: 12.9;Oligodendrocytes: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.6;thyroid cancer: 4.1" "Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050818, HPA054671" Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA050818: AB_2681248, HPA054671: AB_2682568" "unprognostic (3.75e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (4.32e-2)" "unprognostic (1.34e-1)" "unprognostic (6.00e-3)" "unprognostic (1.38e-1)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (8.95e-2)" "unprognostic (4.77e-2)" "unprognostic (2.04e-2)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (9.40e-2)" "unprognostic (1.53e-1)" "unprognostic (1.63e-2)" SLC8B1 "FLJ22233, NCKX6, NCLX, SLC24A6" ENSG00000089060 "Solute carrier family 8 member B1" Q6J4K2 12 113298759-113359493 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 73.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040668 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" "HPA040668: AB_10793861" "prognostic favorable (9.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.27e-1)" "unprognostic (4.30e-1)" "unprognostic (1.93e-2)" "unprognostic (2.80e-3)" "unprognostic (1.90e-1)" "unprognostic (6.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-2)" "unprognostic (2.60e-1)" "unprognostic (5.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.54e-3)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "prognostic favorable (5.02e-4)" SLC9A1 "APNH, NHE-1, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 74.4;stomach 1: 64.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.9;Gastric mucus-secreting cells: 184.5;Serous glandular cells: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Stomach - Proteolysis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Gastric mucus-secreting cells - Digestion" 4 "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.1;stomach 1: 25.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 44.7;Early spermatids: 58.9;Enteroendocrine cells: 21.9;Gastric mucus-secreting cells: 46.6;Intestinal goblet cells: 26.8;Late spermatids: 27.4;Paneth cells: 30.3;Prostatic glandular cells: 22.9;Undifferentiated cells: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 45: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 16: Intestinal goblet cells - Mucin production" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" SLC9A3 "NHE-3, NHE3" ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 43.9;intestine: 91.0;kidney: 60.4;stomach 1: 48.7" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 8.6;Squamous epithelial cells: 7.6" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 49: Non-specific - Transcription" 1 "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 52.4" "Cell type enriched" "Detected in some" 5 "Gastric mucus-secreting cells: 58.4" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Skin - Eccrine sweat gland cells" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.3" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 46: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.9;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 10.7;Horizontal cells: 16.4;Inhibitory neurons: 11.7;Oligodendrocyte precursor cells: 6.6;Spermatocytes: 16.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041004, HPA041329" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" SLC9A6 "KIAA0267, NHE-6, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 37.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" SLC9A7 "NHE-7, NHE7" ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "dendritic cells: 53.1;Excitatory neurons: 41.9;Inhibitory neurons: 64.0;Oligodendrocyte precursor cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Vesicles "HPA048938: AB_2680565, HPA075385: AB_2686747" "unprognostic (2.77e-1)" "unprognostic (4.68e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.58e-4)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.16e-2)" "unprognostic (2.73e-3)" "unprognostic (5.26e-3)" "unprognostic (1.28e-2)" "unprognostic (9.25e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (7.20e-2)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" SLC9A8 "KIAA0939, NHE8" ENSG00000197818 "Solute carrier family 9 member A8" Q9Y2E8 20 49812713-49892242 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Differentiation, Ion transport, Sodium transport, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033682 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Monocytes - Innate immune response" "CAB033682: AB_2270441" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (6.11e-2)" "unprognostic (2.73e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-2)" "unprognostic (4.49e-2)" "unprognostic (3.22e-1)" "unprognostic (3.96e-2)" "unprognostic (5.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.32e-1)" "unprognostic (2.19e-2)" "unprognostic (1.96e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (5.28e-2)" SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 142.1;Inhibitory neurons: 154.1;Microglial cells: 378.4;Oligodendrocyte precursor cells: 256.1;Oligodendrocytes: 401.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 9.3" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 280000 "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA058234: AB_2683648" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (7.23e-3)" "unprognostic (1.65e-1)" "unprognostic (3.65e-2)" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.66e-1)" "unprognostic (1.35e-3)" "unprognostic (7.73e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (5.57e-7)" "unprognostic (5.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-2)" SLC9B1 "NHA1, NHEDC1" ENSG00000164037 "Solute carrier family 9 member B1" Q4ZJI4 4 102885048-103019719 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Fertilization, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 39.2" "Group enriched" "Detected in many" 4 "Early spermatids: 201.1;Late spermatids: 97.5;Spermatocytes: 170.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058971, HPA065520" Supported "Centriolar satellite,Mitochondria" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Mitochondria "Centriolar satellite" "HPA058971: AB_2683865, HPA065520: AB_2685502" "unprognostic (4.87e-3)" "unprognostic (2.38e-1)" "unprognostic (1.18e-1)" "unprognostic (8.26e-4)" "unprognostic (2.53e-1)" "unprognostic (3.39e-1)" "unprognostic (5.06e-4)" "unprognostic (5.85e-2)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.07e-3)" "unprognostic (7.68e-2)" "unprognostic (3.03e-2)" "unprognostic (3.33e-1)" "unprognostic (1.85e-1)" "unprognostic (5.66e-5)" "unprognostic (5.78e-2)" SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.9;Exocrine glandular cells: 34.6;Hepatocytes: 37.3;Inhibitory neurons: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.9" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.9;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" SLC9C2 "MGC43026, SLC9A11" ENSG00000162753 "Solute carrier family 9 member C2 (putative)" Q5TAH2 1 173500460-173603072 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.8" "Cell type enhanced" "Detected in some" "Astrocytes: 25.7;Ciliated cells: 4.1;Cone photoreceptor cells: 5.1;Early spermatids: 6.0;Excitatory neurons: 4.8;Granulosa cells: 6.6;Microglial cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA059122, HPA079529" Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA059122: , HPA079529: " "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (8.52e-2)" "unprognostic (5.88e-3)" "unprognostic (3.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-3)" "unprognostic (1.19e-1)" "unprognostic (4.21e-2)" "unprognostic (4.92e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-6)" "unprognostic (1.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.98e-1)" "unprognostic (1.81e-1)" SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 60.5;salivary gland: 15.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 453.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 610 "liver: 521.0" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 155.9" "Cancer enriched" "Detected in some" 96 "liver cancer: 52.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Liver - Hepatocytes" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane" "HPA050892: AB_2681265, HPA073093: " "unprognostic (5.45e-1)" "unprognostic (1.82e-4)" "unprognostic (2.43e-3)" "unprognostic (1.96e-3)" "unprognostic (1.80e-1)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (5.63e-2)" "unprognostic (3.86e-2)" "unprognostic (3.49e-1)" SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 256.8" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 198.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 5.4" "Region enriched" "Detected in some" 30 "choroid plexus: 34.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.7" "Liver - Hepatocytes" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane" "HPA004943: AB_1854758, HPA050892: AB_2681265" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (7.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.54e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (2.36e-3)" SLCO1B3-SLCO1B7 "LST-3TM12, OATP1B3-1B7" ENSG00000257046 "SLCO1B3-SLCO1B7 readthrough" 12 20815674-21090245 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 21.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.7;Gallbladder cancer: 3.0" HPA050892 Uncertain NA NA "Cluster 73: Breast - Lactation" "Cluster 57: Stomach & Colon cancer - Digestion" "HPA050892: AB_2681265" "unprognostic (2.74e-1)" "unprognostic (1.39e-3)" "unprognostic (3.44e-1)" SLCO2A1 "MATR1, OATP2A1, PGT, SLC21A2" ENSG00000174640 "Solute carrier organic anion transporter family member 2A1" Q92959 3 133932701-134052184 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 119.9" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 108.1;Endothelial cells: 123.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 18.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.2" "Colon - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA013742 Enhanced NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA013742: AB_2668877" "unprognostic (4.39e-3)" "unprognostic (2.84e-1)" "unprognostic (1.33e-1)" "prognostic favorable (9.69e-4)" "unprognostic (8.53e-2)" "unprognostic (2.32e-3)" "prognostic favorable (9.24e-5)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (2.04e-2)" "unprognostic (6.87e-2)" "unprognostic (5.63e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (3.07e-2)" SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 222.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 186.2;Hofbauer cells: 106.9;Kupffer cells: 167.9;Lymphatic endothelial cells: 69.3;Macrophages: 104.1;Microglial cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 19.3;liver cancer: 20.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 582.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 70: DU4475 - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" "HPA066327: AB_2732743" "unprognostic (1.05e-3)" "prognostic favorable (8.61e-4)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.57e-6)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-2)" "unprognostic (1.49e-2)" "unprognostic (2.64e-2)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.5" "Cell type enhanced" "Detected in many" "Adipocytes: 61.0;Endothelial cells: 58.9;Extravillous trophoblasts: 269.5;Melanocytes: 72.1" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in all" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 30: Heart muscle - Heart development" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 40.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 42.5;Early spermatids: 26.3;NK-cells: 17.3;Proximal tubular cells: 25.1" "Cancer enriched" "Detected in many" 5 "renal cancer: 22.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.8" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (1.63e-2)" "unprognostic (2.47e-2)" "unprognostic (4.48e-4)" "unprognostic (5.70e-6)" "unprognostic (7.43e-2)" "unprognostic (7.71e-3)" "unprognostic (3.24e-3)" "unprognostic (2.05e-3)" "unprognostic (2.13e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-3)" "unprognostic (5.83e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (8.22e-2)" SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4;skeletal muscle: 7.3;tongue: 10.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 20.8;Inhibitory neurons: 28.8;Oligodendrocyte precursor cells: 24.5;Plasma cells: 11.6;Prostatic glandular cells: 20.5;Skeletal myocytes: 24.4" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 19.5" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in many" 7 "olfactory bulb: 17.5" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 35: Non-specific - Mitochondria" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" SLCO6A1 "CT48, MGC26949, OATP6A1, OATPY" ENSG00000205359 "Solute carrier organic anion transporter family member 6A1" Q86UG4 5 102371774-102499016 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 110 "testis: 29.4" "Group enriched" "Detected in some" 8 "Early spermatids: 224.2;Spermatocytes: 102.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Region enhanced" "Detected in some" "hippocampal formation: 1.8" HPA054126 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA054126: AB_2682390" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (4.37e-2)" "unprognostic (4.65e-1)" "unprognostic (1.84e-1)" "unprognostic (2.60e-2)" "unprognostic (6.70e-2)" SLF1 "ANKRD32, BRCTD1, BRCTx, DKFZp564C0469, DKFZp761C121" ENSG00000133302 "SMC5-SMC6 complex localization factor 1" Q9BQI6 5 94618669-94739436 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.3;Spermatocytes: 146.5;Spermatogonia: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040793, HPA054213" Uncertain Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA040793: AB_10796560, HPA054213: AB_2682419" "unprognostic (7.56e-2)" "unprognostic (1.45e-2)" "unprognostic (2.44e-3)" "unprognostic (1.02e-1)" "unprognostic (1.68e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-5)" "unprognostic (1.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (6.57e-6)" "unprognostic (3.27e-2)" "unprognostic (2.83e-1)" "unprognostic (1.77e-1)" "unprognostic (8.32e-2)" SLF2 "C10orf6, FAM178A, FLJ10512, FLJ25012" ENSG00000119906 "SMC5-SMC6 complex localization factor 2" Q8IX21 10 100912963-100965134 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 107.3;Oligodendrocytes: 187.9;Peritubular cells: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038499, HPA057568" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 6: Ovarian stromal cells - Transcription" 6 "Nucleoplasm, Vesicles" "HPA038499: AB_10672520, HPA057568: AB_2683471" "unprognostic (9.05e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-2)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (2.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.66e-2)" "unprognostic (1.54e-2)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (4.90e-2)" "unprognostic (1.39e-1)" "unprognostic (2.41e-1)" SLFN12L ENSG00000205045 "Schlafen family member 12 like" 17 35464249-35537678 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.6" "Group enriched" "Detected in some" 11 "NK-cells: 36.1;T-cells: 14.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" HPA024447 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 248.8;Inhibitory neurons: 524.8;Oligodendrocytes: 147.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" "Developmental protein" NA NA 77000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 1 "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" SLITRK1 "KIAA1910, LRRC12" ENSG00000178235 "SLIT and NTRK like family member 1" Q96PX8 13 83877205-83882474 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 14.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 20.1;Excitatory neurons: 17.8;Inhibitory neurons: 13.4;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 13.3" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074835 Enhanced "Secreted in brain" "No annotated function" NA NA 330000 "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 25: Bipolar cells - Visual perception" 1 "HPA074835: " "unprognostic (2.29e-1)" "unprognostic (4.32e-1)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (7.95e-2)" SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.7;fallopian tube: 9.3;liver: 7.7" "Group enriched" "Detected in some" 6 "Bipolar cells: 6.0;Excitatory neurons: 10.6;Inhibitory neurons: 15.2;Oligodendrocyte precursor cells: 19.8" "Cancer enriched" "Detected in single" 22 "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 10.6;prostate cancer: 2.8" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 2600000 "Cluster 64: Neuronal - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 1 Mitochondria "HPA017636: AB_1857232, HPA048042: AB_2732542" "unprognostic (8.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.08e-2)" "unprognostic (1.96e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.74e-3)" "unprognostic (5.03e-1)" "unprognostic (2.38e-1)" "unprognostic (8.03e-4)" SLITRK4 DKFZp547M2010 ENSG00000179542 "SLIT and NTRK like family member 4" Q8IW52 X 143622790-143636101 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.8;brain: 10.2;skeletal muscle: 8.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 50.6;Inhibitory neurons: 46.6;Leydig cells: 47.9;Oligodendrocyte precursor cells: 27.8;Skeletal myocytes: 20.5" "Cancer enriched" "Detected in many" 4 "renal cancer: 3.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.7" "Group enriched" "Detected in many" 64 "dendritic cells: 3.2;granulocytes: 11.7;monocytes: 4.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.3" "Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000431 Enhanced NA NA 420000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 79: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA000431: AB_2665991" "unprognostic (1.72e-1)" "unprognostic (2.11e-2)" "unprognostic (2.63e-2)" "unprognostic (1.15e-3)" "unprognostic (4.09e-1)" "unprognostic (1.75e-2)" "unprognostic (3.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.97e-2)" "unprognostic (1.86e-1)" "unprognostic (3.64e-2)" "unprognostic (9.61e-2)" "unprognostic (6.02e-2)" "unprognostic (1.02e-5)" "unprognostic (1.29e-2)" "unprognostic (7.75e-2)" "unprognostic (9.23e-3)" SLITRK5 "bA364G4.2, KIAA0918, LRRC11" ENSG00000165300 "SLIT and NTRK like family member 5" O94991 13 87671371-87696272 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.5;fallopian tube: 9.8;salivary gland: 9.5" "Cell type enhanced" "Detected in some" "dendritic cells: 32.3;Excitatory neurons: 19.7;Horizontal cells: 13.2;Inhibitory neurons: 12.8;Schwann cells: 19.1;Secretory cells: 13.3;Serous glandular cells: 26.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013843, HPA073230" Uncertain Approved Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles "HPA013843: AB_1857233, HPA073230: " "unprognostic (1.92e-1)" "unprognostic (1.01e-2)" "unprognostic (3.82e-1)" "unprognostic (7.11e-4)" "unprognostic (6.94e-2)" "unprognostic (8.57e-3)" "unprognostic (1.63e-1)" "unprognostic (8.58e-3)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.10e-2)" "unprognostic (1.81e-2)" "unprognostic (2.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.9;urinary bladder: 14.2" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.2;Bipolar cells: 38.6;Club cells: 32.8;Ionocytes: 30.6;Mucus glandular cells: 48.7;Salivary duct cells: 40.8;Schwann cells: 21.0" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 40.6" "Lung - Respiratory ciliated cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 48: Stomach - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" SLMAP "KIAA1601, SLAP" ENSG00000163681 "Sarcolemma associated protein" Q14BN4 3 57755450-57930003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 476.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002357, HPA002358" Enhanced Approved "Endoplasmic reticulum" NA NA 9200 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 "Endoplasmic reticulum" "HPA002357: AB_1080023, HPA002358: AB_1080021" "unprognostic (3.70e-1)" "unprognostic (2.87e-2)" "unprognostic (1.82e-3)" "unprognostic (3.43e-2)" "unprognostic (3.34e-1)" "unprognostic (6.18e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.58e-6)" "unprognostic (8.18e-2)" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (6.08e-2)" SLN "MGC12301, MGC125854, MGC125855" ENSG00000170290 Sarcolipin O00631 11 107707378-107719693 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 7908.9;tongue: 3263.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 910.6;Skeletal myocytes: 2553.7" "Group enriched" "Detected in many" 5 "glioma: 21.6;head and neck cancer: 22.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 35 "Rhabdoid: 202.2" "Skin - Inner root sheath cells" CAB011628 Approved Microtubules NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 Microtubules "CAB011628: AB_2195046" "unprognostic (6.85e-2)" "unprognostic (6.18e-8)" "unprognostic (2.60e-1)" "unprognostic (3.66e-2)" "unprognostic (2.40e-3)" "unprognostic (4.12e-3)" "unprognostic (5.28e-3)" "unprognostic (1.31e-2)" "unprognostic (2.76e-1)" "unprognostic (6.35e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.52e-9)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "unprognostic (5.09e-4)" "unprognostic (3.77e-2)" SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 36: Late spermatids - Unknown function" 19 "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 135.9;placenta: 99.0" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 1246.5;Syncytiotrophoblasts: 745.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 35 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" SMCO2 "C12orf70, LOC341346" ENSG00000165935 "Single-pass membrane protein with coiled-coil domains 2" A6NFE2 12 27446736-27502185 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Excitatory neurons: 9.1;Inhibitory neurons: 3.5;Late spermatids: 5.4;Pancreatic endocrine cells: 3.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014366 Uncertain NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" "HPA014366: AB_1845544" "unprognostic (2.64e-2)" "unprognostic (3.11e-1)" "unprognostic (1.33e-2)" "unprognostic (4.10e-2)" "unprognostic (4.44e-3)" "unprognostic (1.98e-2)" "unprognostic (7.86e-3)" "unprognostic (5.44e-3)" "unprognostic (2.81e-1)" "unprognostic (8.86e-2)" "unprognostic (9.21e-5)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (5.48e-2)" "unprognostic (3.01e-1)" "unprognostic (3.65e-1)" "unprognostic (1.69e-1)" SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.3;kidney: 2.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Collecting duct cells: 1.9;Distal tubular cells: 9.2;Prostatic glandular cells: 1.8;Proximal tubular cells: 6.0;Schwann cells: 4.5" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 1.4" "Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.3" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 3 "Plasma membrane" Cytosol "HPA040574: AB_2677026, HPA047804: AB_2680160" "unprognostic (1.16e-1)" "unprognostic (2.09e-4)" "unprognostic (2.40e-4)" "unprognostic (5.10e-2)" "unprognostic (3.88e-2)" "unprognostic (6.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (1.48e-8)" "unprognostic (2.85e-1)" "unprognostic (7.53e-3)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 189.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 202.8;Proximal enterocytes: 189.6;Serous glandular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" 51 "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 3 Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Uncertain "Cytoplasmic bodies" No No "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 1 "Cytoplasmic bodies" "HPA072651: AB_2686544" "unprognostic (2.09e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (3.20e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.70e-9)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.26e-2)" SMG8 "C17orf71, FLJ10587, FLJ23205" ENSG00000167447 "SMG8 nonsense mediated mRNA decay factor" Q8ND04 17 59209400-59215239 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024841 Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Non-specific - Transcription" 1 Nucleoplasm "HPA024841: AB_10600790" "unprognostic (2.68e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-3)" "unprognostic (9.91e-2)" "unprognostic (8.59e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (1.91e-1)" "unprognostic (1.15e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-3)" "unprognostic (4.65e-2)" "unprognostic (9.37e-2)" "unprognostic (4.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-1)" SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 92.8;Late spermatids: 328.5;Syncytiotrophoblasts: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 32 "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;heart muscle: 38.9;testis: 41.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Erythroid cells: 290.3;granulocytes: 87.1;Proximal tubular cells: 223.9;Sertoli cells: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.7" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.7" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA069088 Enhanced NA NA 340000 "Cluster 22: Eosinophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 48 "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" SMIM11 "C21orf51, FAM165B, SMIM11A" ENSG00000205670 "Small integral membrane protein 11" P58511 21 34375480-34416961 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 4.7;Peritubular cells: 5.2;Sertoli cells: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 55: Non-specific - Transcription" 2 "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (2.62e-2)" "unprognostic (4.28e-2)" "unprognostic (1.27e-1)" "unprognostic (5.86e-3)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (3.04e-1)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" "unprognostic (8.84e-2)" "unprognostic (4.83e-3)" SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" SMIM13 C6orf228 ENSG00000224531 "Small integral membrane protein 13" P0DJ93 6 11093834-11138733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 29.7" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065706 Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA065706: AB_2685539" "unprognostic (6.89e-2)" "unprognostic (1.22e-1)" "unprognostic (1.58e-1)" "unprognostic (7.11e-3)" "unprognostic (4.01e-1)" "unprognostic (2.57e-1)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (6.66e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.04e-2)" "unprognostic (2.76e-1)" "unprognostic (9.22e-2)" "unprognostic (3.45e-2)" SMIM14 "C4orf34, FLJ13289" ENSG00000163683 "Small integral membrane protein 14" Q96QK8 4 39546336-39638902 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 553.1;Intestinal goblet cells: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051299 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 16: Intestinal goblet cells - Mucin production" 5 "HPA051299: AB_2681429" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.48e-2)" "prognostic favorable (3.00e-6)" "prognostic favorable (3.47e-4)" "unprognostic (2.67e-2)" "unprognostic (1.54e-1)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (7.18e-2)" "prognostic favorable (2.07e-4)" "unprognostic (6.66e-2)" "unprognostic (1.33e-1)" "unprognostic (9.50e-2)" "unprognostic (4.92e-3)" SMIM17 ENSG00000268182 "Small integral membrane protein 17" P0DL12 19 56643159-56657247 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 8.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Bipolar cells: 6.3;Excitatory neurons: 17.4;Inhibitory neurons: 31.3" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071857, HPA071861" Enhanced Approved Vesicles NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA071857: AB_2686461, HPA071861: AB_2686462" "unprognostic (1.32e-1)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.62e-1)" "unprognostic (4.57e-2)" "unprognostic (5.84e-2)" "unprognostic (3.00e-2)" "unprognostic (2.51e-1)" "unprognostic (6.50e-2)" "unprognostic (4.64e-2)" "unprognostic (9.02e-3)" "unprognostic (3.46e-3)" "unprognostic (6.26e-2)" "unprognostic (1.01e-1)" "unprognostic (3.71e-3)" "unprognostic (7.51e-3)" SMIM18 ENSG00000253457 "Small integral membrane protein 18" P0DKX4 8 30638580-30646064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 8.8;pituitary gland: 5.2;retina: 3.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.3;Excitatory neurons: 2.8;Horizontal cells: 7.6;Inhibitory neurons: 5.0;Microglial cells: 4.5;Oligodendrocyte precursor cells: 5.2;Proximal tubular cells: 3.5" "Cancer enriched" "Detected in single" 8 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.6" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066648 Supported Uncertain Nucleoplasm,Centrosome NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 25: Bipolar cells - Visual perception" Nucleoplasm Centrosome "HPA066648: AB_2685697" "unprognostic (2.19e-2)" "unprognostic (9.37e-2)" "unprognostic (3.31e-1)" "unprognostic (4.24e-2)" "unprognostic (1.66e-1)" "unprognostic (2.60e-1)" "unprognostic (7.29e-2)" "unprognostic (4.70e-1)" "unprognostic (8.91e-3)" "unprognostic (1.05e-1)" "unprognostic (2.36e-1)" "unprognostic (6.08e-2)" "unprognostic (4.01e-3)" "unprognostic (1.33e-1)" "unprognostic (3.25e-1)" "unprognostic (4.14e-1)" SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 4 "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" SMIM2 "C13orf44, MGC5590" ENSG00000139656 "Small integral membrane protein 2" Q9BVW6 13 44143150-44161257 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 22.8" "Cell type enriched" "Detected in some" 5 "Early spermatids: 70.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "HPA026891, HPA077071" Enhanced Uncertain "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Early spermatids - Unknown function" 2 "Nucleoplasm, Nuclear bodies" "HPA026891: AB_10602924, HPA077071: " "unprognostic (4.34e-2)" "unprognostic (8.70e-2)" "unprognostic (1.07e-1)" "unprognostic (4.87e-5)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (3.26e-1)" "unprognostic (1.26e-1)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-1)" "unprognostic (1.00e-1)" "unprognostic (2.10e-1)" "unprognostic (4.80e-2)" "unprognostic (2.39e-2)" "unprognostic (1.05e-2)" SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929813 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: AB_1859536" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.42e-2)" "unprognostic (2.86e-1)" "prognostic favorable (8.97e-5)" "unprognostic (5.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" SMIM21 C18orf62 ENSG00000206026 "Small integral membrane protein 21" Q3B7S5 18 75409476-75427703 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.7" "Group enriched" "Detected in some" 88 "Early spermatids: 79.6;Late spermatids: 52.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA041686 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Early spermatids - Unknown function" 1 "HPA041686: AB_10961179" "unprognostic (7.45e-2)" SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 188.3;pancreas: 149.9;salivary gland: 142.9;stomach 1: 196.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2064.5;Enteroendocrine cells: 620.1;Intestinal goblet cells: 1141.8;Paneth cells: 999.8;Proximal enterocytes: 1718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 142.5;colorectal cancer: 173.2" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1541.7;intestine: 731.3;kidney: 810.9" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 4214.7;Proximal tubular cells: 1477.7" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.7;pancreatic cancer: 37.4;renal cancer: 78.4;stomach cancer: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Gastric cancer: 35.6;Leukemia: 96.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Cytosol "HPA045046: AB_10964444, HPA056027: AB_2683012" "unprognostic (2.18e-4)" "unprognostic (4.63e-1)" "unprognostic (5.68e-2)" "unprognostic (9.60e-2)" "unprognostic (1.93e-1)" "unprognostic (6.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.13e-10)" "unprognostic (1.68e-2)" "unprognostic (2.14e-1)" "unprognostic (8.36e-2)" "unprognostic (3.11e-2)" SMIM26 "LINC00493, LOC388789" ENSG00000232388 "Small integral membrane protein 26" A0A096LP01 20 18567347-18569563 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 596.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068733 Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 64: Non-specific - Ribosome" Nucleoplasm Cytosol "HPA068733: AB_2686024" "unprognostic (1.20e-2)" "unprognostic (5.85e-2)" "unprognostic (2.83e-1)" "unprognostic (8.06e-2)" "unprognostic (2.68e-1)" "unprognostic (1.65e-1)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.67e-3)" "unprognostic (2.16e-1)" "unprognostic (2.68e-2)" "unprognostic (2.40e-2)" "unprognostic (2.02e-1)" "unprognostic (3.18e-1)" "prognostic favorable (7.84e-5)" SMIM29 "C6orf1, LBH, MGC57858" ENSG00000186577 "Small integral membrane protein 29" Q86T20 6 34246381-34249108 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 104.7;Melanocytes: 120.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 414.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037659, HPA037660" Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" "HPA037659: AB_2675591, HPA037660: AB_10671881" "unprognostic (2.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.10e-1)" "unprognostic (3.23e-1)" "unprognostic (1.93e-3)" "unprognostic (1.36e-2)" "unprognostic (2.62e-1)" "unprognostic (4.12e-2)" "prognostic favorable (7.98e-4)" "unprognostic (9.32e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (3.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.66e-1)" SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 155.4" "Cell type enhanced" "Detected in many" "dendritic cells: 198.1;granulocytes: 96.2;Smooth muscle cells: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075345 Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 57: Platelets - Hemostasis" 44 Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" SMIM34 SMIM34A ENSG00000243627 "Small integral membrane protein 34" A8MWV9 21 34418715-34423951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lung cancer: 1.3;prostate cancer: 3.9" "Not detected" "Not detected" HPA029085 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "HPA029085: AB_10669867" SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 118.1;skeletal muscle: 125.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 291.5;Distal tubular cells: 304.3;Proximal tubular cells: 254.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA047771: AB_2680150" "unprognostic (3.76e-3)" "unprognostic (3.19e-2)" "unprognostic (4.54e-2)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.48e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.78e-5)" "unprognostic (3.25e-2)" "unprognostic (4.25e-2)" "prognostic favorable (5.00e-4)" "unprognostic (6.35e-2)" "prognostic favorable (1.63e-4)" "unprognostic (8.72e-3)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 60.6;Collecting duct cells: 112.8;dendritic cells: 77.5;Distal tubular cells: 95.3;Erythroid cells: 68.8;Glandular and luminal cells: 72.8;Schwann cells: 92.5;Suprabasal keratinocytes: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.9" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.9" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 7 Vesicles "Golgi apparatus" "HPA065332: AB_2685471, HPA071268: AB_2686377" "unprognostic (6.97e-2)" "prognostic favorable (5.52e-4)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-4)" "unprognostic (3.29e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (3.52e-3)" "unprognostic (1.10e-1)" "prognostic favorable (1.12e-4)" "unprognostic (2.64e-1)" "unprognostic (4.94e-2)" "unprognostic (8.26e-2)" "unprognostic (2.58e-1)" SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.3;kidney: 21.5;stomach 1: 32.3;testis: 25.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1339.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.2;Kidney cancer: 9.2" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 46: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" Nucleoplasm "HPA065721: AB_2685546" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (7.07e-2)" "prognostic favorable (1.49e-4)" "unprognostic (3.42e-1)" "unprognostic (1.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (8.06e-2)" "prognostic favorable (4.09e-4)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.58e-2)" "prognostic favorable (1.64e-4)" SMIM7 "C19orf42, MGC2747" ENSG00000214046 "Small integral membrane protein 7" Q9BQ49 19 16630751-16660442 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043127 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "HPA043127: AB_10806378" "unprognostic (6.61e-2)" "unprognostic (1.61e-2)" "unprognostic (1.90e-1)" "unprognostic (3.71e-2)" "unprognostic (2.52e-1)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "unprognostic (1.79e-2)" "unprognostic (6.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-3)" "unprognostic (8.29e-3)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (7.64e-2)" SMIM8 "C6orf162, dJ102H19.2, DKFZP586E1923" ENSG00000111850 "Small integral membrane protein 8" Q96KF7 6 87322583-87399749 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007401, HPA067453" Approved Approved Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 3: Non-specific - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 68: Cardiomyocytes - Muscle contraction" Vesicles "HPA007401: AB_1078357, HPA067453: AB_2685844" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (1.56e-2)" "unprognostic (3.16e-2)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (5.31e-2)" "unprognostic (6.12e-3)" "unprognostic (1.86e-5)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (3.06e-2)" "unprognostic (2.86e-2)" "unprognostic (4.01e-1)" SMIM9 CXorf68 ENSG00000203870 "Small integral membrane protein 9" A6NGZ8 X 154823348-154834662 "Predicted membrane proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Early spermatids: 30.7;Late spermatids: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060970 Uncertain NA NA "Cluster 18: Early spermatids - Unknown function" "HPA060970: AB_2684399" "unprognostic (2.63e-5)" SMLR1 ENSG00000256162 "Small leucine rich protein 1" H3BR10 6 130827406-130837135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 54.9" "Group enriched" "Detected in some" 18 "Hepatocytes: 317.3;Proximal enterocytes: 144.0" "Cancer enriched" "Detected in some" 20 "liver cancer: 16.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "liver cancer: 6.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066060 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA066060: AB_2685607" "unprognostic (1.73e-1)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.32e-2)" "unprognostic (2.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (6.43e-3)" "unprognostic (2.68e-3)" "unprognostic (3.29e-1)" SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.0;Leydig cells: 19.9;Muller glia cells: 13.7;Peritubular cells: 21.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 1 "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 51.5" "Group enriched" "Detected in many" 4 "Early spermatids: 163.4;Late spermatids: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 17: Choroid plexus - Cilium" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" 11 "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.8;lymphoid tissue: 50.7" "Cell type enhanced" "Detected in many" "dendritic cells: 221.5;Gastric mucus-secreting cells: 61.3;Horizontal cells: 71.8;Oocytes: 75.0;Proximal enterocytes: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 139.0" "Lineage enriched" "Detected in many" 7 "dendritic cells: 139.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;lymphoma: 12.1;Neuroblastoma: 11.2" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Peritubular cells" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 83.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 16.2;Squamous epithelial cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" "Nuclear membrane" Cytosol "HPA046279: AB_2679611, HPA049426: AB_2680762" "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.73e-4)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 681.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane" NA NA 3900000 "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 57: Platelets - Hemostasis" 7 "Plasma membrane" "CAB037083: AB_477494, CAB037317: AB_261925, HPA001214: AB_1080037" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.76e-3)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (9.67e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (8.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" SNAP47 "C1orf142, SNAP-47, SVAP1" ENSG00000143740 "Synaptosome associated protein 47" Q5SQN1 1 227728200-227781826 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 98.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028167 Supported Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 6: Ovarian stromal cells - Transcription" 21 Cytosol "HPA028167: AB_10603032" "unprognostic (3.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.93e-2)" "unprognostic (7.31e-2)" "unprognostic (4.88e-2)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-2)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (6.14e-2)" "unprognostic (4.81e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" SNN ENSG00000184602 Stannin O75324 16 11668455-11679152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 168.2;skeletal muscle: 110.8" "Cell type enhanced" "Detected in many" "Langerhans cells: 124.2;monocytes: 173.5;Muller glia cells: 139.1" "Cancer enhanced" "Detected in all" "glioma: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Gallbladder cancer: 123.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011055 Approved Uncertain Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 57: Platelets - Hemostasis" Cytosol "HPA011055: AB_1857326" "unprognostic (1.94e-1)" "unprognostic (7.26e-2)" "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (4.51e-2)" "unprognostic (3.45e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (2.14e-1)" "prognostic favorable (1.83e-5)" "unprognostic (4.91e-2)" "unprognostic (2.09e-1)" "unprognostic (3.58e-1)" "unprognostic (4.72e-2)" SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 84.5;skin 1: 31.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 393.3;Breast myoepithelial cells: 338.2;Distal enterocytes: 121.1;Hepatocytes: 113.3;Intestinal goblet cells: 129.9;Melanocytes: 211.3;Muller glia cells: 101.1;Undifferentiated cells: 107.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 2.5" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 20 "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" SNPH bA314N13.5 ENSG00000101298 Syntaphilin O15079 20 1266280-1309328 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 72.0" "Cell type enhanced" "Detected in many" "Astrocytes: 43.3;Bipolar cells: 24.4;Excitatory neurons: 58.5;Horizontal cells: 23.3;Inhibitory neurons: 68.8;Oligodendrocyte precursor cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049393 Approved Uncertain "Cytokinetic bridge,Mitochondria" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 2 Mitochondria "Cytokinetic bridge" "HPA049393: AB_2680744" "unprognostic (1.43e-2)" "unprognostic (2.55e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (2.56e-2)" "unprognostic (5.33e-2)" "unprognostic (3.08e-2)" "unprognostic (3.15e-2)" "prognostic favorable (6.97e-5)" "unprognostic (1.03e-1)" "unprognostic (6.94e-3)" "unprognostic (2.45e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" SNRNP40 "HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57" ENSG00000060688 "Small nuclear ribonucleoprotein U5 subunit 40" Q96DI7 1 31259568-31296788 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026527, HPA027345" Supported Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 9 "Nuclear speckles" "HPA026527: AB_1858814, HPA027345: AB_2239703" "unprognostic (2.31e-3)" "unprognostic (5.63e-2)" "unprognostic (5.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-3)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.73e-6)" "unprognostic (2.14e-2)" "unprognostic (2.43e-2)" "unprognostic (2.50e-1)" "unprognostic (1.22e-1)" "unprognostic (8.57e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-2)" "unprognostic (5.93e-2)" "unprognostic (4.31e-2)" "unprognostic (6.24e-2)" SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85504776-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Group enriched" "Detected in all" 4 "granulocytes: 19.2;monocytes: 12.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" "Vesicles, Cytosol" "HPA017639: AB_1857345" "unprognostic (1.16e-2)" "unprognostic (3.29e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (1.57e-2)" "unprognostic (3.14e-2)" "unprognostic (2.37e-2)" "unprognostic (1.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (4.72e-3)" SNX19 "CHET8, KIAA0254" ENSG00000120451 "Sorting nexin 19" Q92543 11 130866250-130916479 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 104.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013447 Uncertain Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 1 Mitochondria "HPA013447: AB_1857347" "unprognostic (8.79e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (9.19e-2)" "unprognostic (3.43e-2)" "unprognostic (4.05e-2)" "unprognostic (2.89e-1)" "unprognostic (4.97e-2)" "prognostic favorable (3.56e-5)" "unprognostic (1.05e-1)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 94.9;Astrocytes: 48.0;Excitatory neurons: 55.7;Inhibitory neurons: 58.1;Oligodendrocyte precursor cells: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 28: Neuronal - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" SOAT1 "ACAT, ACAT1, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 160.1" "Cell type enhanced" "Detected in many" "monocytes: 99.3;Prostatic glandular cells: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 4 "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" SOGA3 "C6orf174, dJ403A15.3" ENSG00000214338 "SOGA family member 3" Q5TF21 6 127472806-127519335 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.0" "Group enriched" "Detected in some" 9 "Excitatory neurons: 75.5;Inhibitory neurons: 55.0;Oligodendrocyte precursor cells: 41.5;Oligodendrocytes: 30.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 45.6" "Lung - Alveolar cells type 1, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035388, HPA035389" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA035388: AB_2674601, HPA035389: AB_10669857" "unprognostic (1.70e-1)" "unprognostic (3.56e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.19e-1)" "unprognostic (8.58e-3)" "unprognostic (8.45e-2)" "unprognostic (7.31e-4)" "unprognostic (5.65e-3)" "unprognostic (1.58e-1)" "unprognostic (3.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.30e-2)" "unprognostic (1.72e-1)" "unprognostic (8.26e-3)" SORCS1 ENSG00000108018 "Sortilin related VPS10 domain containing receptor 1" Q8WY21 10 106573663-107164706 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0;thyroid gland: 10.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 505.5;Inhibitory neurons: 172.2;Oligodendrocyte precursor cells: 358.0;Schwann cells: 101.7" "Cancer enhanced" "Detected in some" "melanoma: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 25.9;Sarcoma: 11.8;skin cancer: 10.6" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011948 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" "HPA011948: AB_1857366" "unprognostic (5.86e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-2)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (1.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.52e-2)" "unprognostic (5.58e-2)" "unprognostic (6.82e-3)" "unprognostic (5.81e-2)" "unprognostic (6.48e-4)" "unprognostic (2.51e-2)" "unprognostic (8.89e-3)" "unprognostic (2.22e-1)" "unprognostic (2.69e-4)" SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6" "Cell type enhanced" "Detected in many" "Astrocytes: 101.6;Bipolar cells: 68.7;Excitatory neurons: 40.0;Muller glia cells: 32.4;Oligodendrocytes: 70.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 47: Astrocytes - Unknown function" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 239.0;Microglial cells: 386.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 126.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 126.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" Receptor NA NA 79000 "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 18 "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 150.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 416.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Oligodendrocytes - Unknown function" 20 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" SPACA1 SAMP32 ENSG00000118434 "Sperm acrosome associated 1" Q9HBV2 6 88047841-88066838 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 390 "testis: 40.7" "Cell type enriched" "Detected in some" 25 "Early spermatids: 1312.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026744, HPA043297" Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 18: Early spermatids - Unknown function" 24 "HPA026744: AB_2194642, HPA043297: AB_2678413" "unprognostic (4.15e-2)" SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 121.8" "Group enriched" "Detected in some" 99 "Early spermatids: 1378.1;Late spermatids: 1100.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cancer enriched" "Detected in single" 11 "Myeloma: 8.3" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA023633: AB_1857407" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.31e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (1.68e-1)" "unprognostic (5.70e-4)" "unprognostic (3.86e-2)" "unprognostic (1.79e-1)" "unprognostic (4.63e-1)" SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 87.3;testis: 31.1" "Group enriched" "Detected in many" 5 "Early spermatids: 153.5;Late spermatids: 166.4;Plasma cells: 234.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Plasma cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 15: Pancreas - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 24 "HPA048393: AB_2680385, HPA061789: AB_2684609" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.09e-5)" "prognostic favorable (9.52e-8)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-2)" "unprognostic (4.49e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "prognostic favorable (6.66e-4)" SPAG9 "CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JIP-4, JIP4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1" ENSG00000008294 "Sperm associated antigen 9" O60271 17 50962174-51120868 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 9.2;neutrophil: 12.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 12.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040446, HPA061458" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 5 "Centriolar satellite, Cytosol" "HPA040446: AB_10671691, HPA061458: AB_2684528" "unprognostic (1.36e-1)" "unprognostic (6.61e-2)" "unprognostic (6.04e-3)" "unprognostic (4.65e-2)" "unprognostic (3.52e-2)" "unprognostic (9.73e-2)" "unprognostic (8.13e-2)" "unprognostic (3.72e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.83e-2)" "unprognostic (9.71e-2)" "unprognostic (2.23e-3)" "unprognostic (2.27e-2)" "unprognostic (9.53e-2)" "unprognostic (7.67e-2)" "prognostic unfavorable (8.10e-4)" SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 16.9" "Group enriched" "Detected in some" 93 "Early spermatids: 334.9;Late spermatids: 122.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 21: Early spermatids - Spermatogenesis" "HPA017984: AB_1857413" "unprognostic (2.44e-1)" SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063556-32157637 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" SPATA3 TSARG1 ENSG00000173699 "Spermatogenesis associated 3" Q8NHX4 2 230990324-231025055 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 475 "testis: 171.8" "Cell type enriched" "Detected in some" 12 "Late spermatids: 5210.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 14 "cerebellum: 4.9" HPA018254 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 36: Late spermatids - Unknown function" "HPA018254: AB_1857419" "unprognostic (6.94e-3)" "unprognostic (6.98e-2)" "unprognostic (9.62e-2)" SPATA31D1 "FAM75D1, FLJ46321" ENSG00000214929 "SPATA31 subfamily D member 1" Q6ZQQ2 9 81988772-81995253 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 10.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 71.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" HPA047897 Uncertain NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" "HPA047897: AB_2680204" "unprognostic (1.25e-1)" SPATA31E1 "C9orf79, FAM75E1, FLJ35866" ENSG00000177992 "SPATA31 subfamily E member 1" Q6ZUB1 9 87882877-87888903 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 7.3" "Group enriched" "Detected in some" 64 "Early spermatids: 25.2;Late spermatids: 26.3" "Not detected" "Not detected" "Region enriched" "Detected in some" 12 "hippocampal formation: 15.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024253 Enhanced NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" "HPA024253: AB_1845839" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.72e-1)" SPATA9 "FLJ35906, NYD-SP16" ENSG00000145757 "Spermatogenesis associated 9" Q9BWV2 5 95652181-95698711 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 26.0" "Group enriched" "Detected in some" 13 "Early spermatids: 569.2;Late spermatids: 565.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA010848, HPA076967" Approved Approved Mitochondria NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 11: Late spermatids - Unknown function" Mitochondria "HPA010848: AB_1857422, HPA076967: " "unprognostic (4.46e-2)" "unprognostic (4.02e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (9.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.33e-2)" "unprognostic (2.08e-1)" "unprognostic (3.27e-2)" "unprognostic (7.58e-2)" "unprognostic (1.28e-2)" "unprognostic (3.08e-2)" "unprognostic (9.49e-13)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.26e-2)" "unprognostic (2.87e-2)" SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949261-74979033 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 1026.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013386, HPA017351" Approved Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 3 Vesicles "HPA013386: AB_1857426, HPA017351: " "unprognostic (2.43e-1)" "unprognostic (7.01e-2)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (9.30e-2)" "unprognostic (2.31e-2)" "unprognostic (7.04e-3)" "unprognostic (9.61e-2)" "unprognostic (8.83e-2)" "unprognostic (2.02e-3)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (5.70e-2)" "unprognostic (1.37e-1)" "unprognostic (8.62e-2)" SPEM2 C17orf74 ENSG00000184560 "SPEM family member 2" Q0P670 17 7425616-7427568 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 573 "testis: 124.5" "Cell type enriched" "Detected in some" 12 "Late spermatids: 2324.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023649 Uncertain Approved "Golgi apparatus" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus" "HPA023649: AB_1845606" "unprognostic (3.00e-1)" "unprognostic (3.88e-1)" "unprognostic (1.12e-4)" "unprognostic (1.25e-1)" SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44554818-44663688 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 73: B-cells - B-cell function" 2 "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, RNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 331.3;lung: 97.9;lymphoid tissue: 168.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 484.1;Kupffer cells: 311.1;Langerhans cells: 611.3;Macrophages: 436.9;monocytes: 544.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 180.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 180.0" "Group enriched" "Detected in some" 15 "Leukemia: 134.6;lymphoma: 69.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" SPIN3 TDRD27 ENSG00000204271 "Spindlin family member 3" Q5JUX0 X 56818298-56995827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.1;Inhibitory neurons: 22.3;Oligodendrocyte precursor cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000727 Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 65: Neurons - Synaptic function" Nucleoplasm "HPA000727: AB_2196121" "unprognostic (3.12e-3)" "unprognostic (2.32e-1)" "unprognostic (7.45e-3)" "prognostic unfavorable (3.49e-4)" "unprognostic (1.20e-2)" "unprognostic (1.67e-2)" "unprognostic (6.85e-4)" "prognostic favorable (6.79e-4)" "unprognostic (1.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.48e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-2)" "unprognostic (6.53e-2)" "unprognostic (8.51e-2)" "unprognostic (1.98e-2)" "prognostic favorable (6.30e-4)" SPINT1 "HAI, HAI-1, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 248.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1211.1;Ductal cells: 415.0;Proximal enterocytes: 467.2;Syncytiotrophoblasts: 1698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" "Enzyme inhibitor" NA NA 7400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" SPINT2 "HAI-2, HAI2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1385.4;Syncytiotrophoblasts: 1381.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" SPN "CD43, GPL115, LEU-22, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 70.9;lung: 27.3;lymphoid tissue: 49.7" "Cell type enhanced" "Detected in many" "dendritic cells: 218.9;Erythroid cells: 123.5;monocytes: 499.5;NK-cells: 248.7;T-cells: 98.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 185.3;Myeloma: 49.9" "Prostate - T-cells, Skin - Langerhans cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 33: Non-specific - ATP binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 6 "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" SPNS1 "HSpin1, LAT, nrs, PP2030, SLC63A1, SPIN1, SPINL" ENSG00000169682 "Sphingolipid transporter 1 (putative)" Q9H2V7 16 28974221-28984548 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041995, HPA042988" Enhanced Approved "Nucleoli fibrillar center,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 2 Vesicles "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA041995: AB_10959609, HPA042988: AB_10964587" "unprognostic (3.54e-2)" "unprognostic (4.57e-4)" "unprognostic (2.15e-1)" "unprognostic (2.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.66e-1)" "unprognostic (7.86e-5)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (4.12e-2)" "unprognostic (3.02e-3)" "unprognostic (8.85e-7)" "unprognostic (1.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.26e-3)" "unprognostic (1.12e-2)" SPNS2 SLC63A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.6" "Cell type enhanced" "Detected in many" "Adipocytes: 35.6;Endothelial cells: 40.1;Extravillous trophoblasts: 35.1;Gastric mucus-secreting cells: 31.8;Microglial cells: 35.8;Oligodendrocytes: 91.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" SPNS3 "MGC29671, SLC63A3" ENSG00000182557 "Sphingolipid transporter 3 (putative)" Q6ZMD2 17 4433940-4488208 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 30.7" "Cell type enhanced" "Detected in many" "dendritic cells: 61.4;Langerhans cells: 19.2;Proximal tubular cells: 45.3;T-cells: 21.4" "Cancer enhanced" "Detected in many" "renal cancer: 2.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 355.4;plasmacytoid DC: 127.9" "Group enriched" "Detected in many" 37 "dendritic cells: 127.9;granulocytes: 355.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 40.9" "Liver - Hepatocytes, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA023928 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA023928: AB_1844393" "unprognostic (4.39e-2)" "unprognostic (8.10e-5)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.94e-4)" "unprognostic (2.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.81e-2)" "unprognostic (6.46e-2)" "unprognostic (1.37e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (6.18e-2)" "unprognostic (6.57e-2)" "unprognostic (4.13e-2)" "unprognostic (9.69e-2)" SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765948 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 100.8;Late spermatids: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 78: Testis - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: AB_2676429" "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favorable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" SPPL2C IMP5 ENSG00000185294 "Signal peptide peptidase like 2C" Q8IUH8 17 45844881-45847067 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 35.8" "Cell type enriched" "Detected in some" 5 "Late spermatids: 609.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077339 Supported NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA077339: " "unprognostic (6.70e-4)" "unprognostic (1.34e-1)" SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 178.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" SPRED1 "FLJ33903, PPP1R147" ENSG00000166068 "Sprouty related EVH1 domain containing 1" Q7Z699 15 38252836-38357249 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 164.7;Excitatory neurons: 158.0;Microglial cells: 190.6;Oligodendrocyte precursor cells: 260.8;Oligodendrocytes: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 4 "monocytes: 1.4" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042193, HPA061805" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 3: Rhabdoid - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" 308 Nucleoplasm "HPA042193: AB_10794079, HPA061805: AB_2684617" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "prognostic favorable (7.08e-4)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" "unprognostic (1.21e-3)" "unprognostic (5.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.81e-3)" "unprognostic (9.27e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (7.37e-5)" "prognostic unfavorable (8.29e-5)" "unprognostic (6.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" SPRED2 "FLJ21897, FLJ31917, Spred-2" ENSG00000198369 "Sprouty related EVH1 domain containing 2" Q7Z698 2 65310851-65432637 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 103.1;Excitatory neurons: 133.9;Inhibitory neurons: 117.2;Oligodendrocyte precursor cells: 116.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 1.9;plasmacytoid DC: 4.3" "Group enriched" "Detected in many" 4 "dendritic cells: 4.3;NK-cells: 1.9" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038256, HPA064394" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 38 Nucleoplasm Cytosol "HPA038256: , HPA064394: AB_2732712" "unprognostic (1.49e-1)" "unprognostic (5.95e-3)" "unprognostic (3.46e-2)" "unprognostic (4.40e-3)" "unprognostic (8.94e-2)" "unprognostic (1.63e-1)" "unprognostic (2.90e-2)" "unprognostic (9.94e-2)" "unprognostic (9.07e-2)" "unprognostic (4.25e-1)" "unprognostic (5.05e-2)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (7.21e-3)" "unprognostic (5.43e-2)" SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;pituitary gland: 5.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 11.0;Excitatory neurons: 9.5;Horizontal cells: 6.9;Inhibitory neurons: 9.9" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 230.5" "Cell type enhanced" "Detected in many" "Adipocytes: 804.9;Endothelial cells: 407.7;Fibroblasts: 223.6;Leydig cells: 404.0;Mesothelial cells: 313.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 59 "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" SPRY2 hSPRY2 ENSG00000136158 "Sprouty RTK signaling antagonist 2" O43597 13 80335976-80341126 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037205, HPA042198" Approved Supported "Actin filaments,Microtubules" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 51 "Actin filaments, Microtubules" "CAB037205: AB_261923, HPA042198: AB_2677896" "unprognostic (9.37e-3)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (9.12e-3)" "unprognostic (3.80e-2)" "unprognostic (8.99e-2)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (4.28e-2)" "unprognostic (1.56e-2)" "unprognostic (9.89e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" SPRY3 HSPRY3 ENSG00000168939 "Sprouty RTK signaling antagonist 3" O43610 X 155612572-155782459 "Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Astrocytes: 40.6;Excitatory neurons: 39.6;Inhibitory neurons: 41.6;Microglial cells: 59.9;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 18.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" CAB013505 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 22 Cytosol Nucleoli "CAB013505: " "unprognostic (3.70e-2)" "unprognostic (4.39e-1)" "unprognostic (5.24e-2)" "unprognostic (3.37e-2)" "unprognostic (3.65e-1)" "unprognostic (1.20e-1)" "unprognostic (7.88e-2)" "unprognostic (1.16e-1)" "unprognostic (3.68e-3)" "unprognostic (1.52e-4)" "unprognostic (1.21e-2)" "unprognostic (9.60e-2)" "unprognostic (5.26e-2)" "unprognostic (6.65e-2)" "unprognostic (1.86e-1)" "unprognostic (5.44e-2)" "unprognostic (3.49e-2)" SPRY4 ENSG00000187678 "Sprouty RTK signaling antagonist 4" Q9C004 5 142310427-142326455 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.5;Alveolar cells type 2: 59.4;Endothelial cells: 28.7;Oligodendrocyte precursor cells: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 70.1" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008086, HPA055471, HPA072661" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Alveolar cells - Lung function" 30 "Golgi apparatus" Cytosol "CAB008086: AB_2195454, HPA055471: AB_2682825, HPA072661: AB_2732207" "unprognostic (9.54e-3)" "prognostic unfavorable (7.12e-4)" "unprognostic (2.18e-1)" "unprognostic (1.16e-1)" "unprognostic (8.70e-2)" "unprognostic (3.23e-2)" "unprognostic (3.98e-3)" "unprognostic (1.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.44e-2)" "unprognostic (1.48e-1)" "unprognostic (9.89e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-3)" "unprognostic (3.63e-2)" "unprognostic (4.59e-2)" "unprognostic (8.21e-2)" SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 21: Early spermatids - Spermatogenesis" 2 "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: AB_2685148" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favorable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 118.9;monocytes: 141.6;Oligodendrocytes: 152.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075143 Approved "Plasma membrane,Cell Junctions" NA No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "Cell Junctions" "HPA075143: " "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favorable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008972-13169103 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.8;Early spermatids: 34.4;Glandular and luminal cells: 47.1;Microglial cells: 34.0;Syncytiotrophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA044247, HPA048079" Enhanced Approved Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 Microtubules "HPA044247: AB_2678872, HPA048079: AB_2680252" "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favorable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 226.4;Syncytiotrophoblasts: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 98.6;Hepatocytes: 96.7;Squamous epithelial cells: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 16.3;Ionocytes: 25.0;Oligodendrocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Non-specific - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favorable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837002 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 212.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 2 "Nucleoplasm, Golgi apparatus, Cytosol" "CAB005406: AB_2194226, HPA043343: AB_2678439, HPA043878: AB_2678710" "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favorable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favorable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" 5 "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" SRPRB "APMCF1, SR-beta" ENSG00000144867 "SRP receptor subunit beta" Q9Y5M8 3 133784023-133825772 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011173 Approved Approved "Plasma membrane" NA NA 12000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "HPA011173: AB_1857484" "unprognostic (5.44e-2)" "unprognostic (1.32e-1)" "unprognostic (6.40e-2)" "unprognostic (1.58e-2)" "unprognostic (2.61e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.99e-1)" "unprognostic (3.60e-2)" "unprognostic (6.07e-3)" "unprognostic (8.45e-2)" "unprognostic (1.31e-2)" "unprognostic (3.79e-2)" "unprognostic (5.08e-2)" "unprognostic (7.37e-2)" "unprognostic (6.47e-2)" "unprognostic (2.26e-2)" SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81412804-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 267.2;Excitatory neurons: 254.1;Inhibitory neurons: 334.7;Microglial cells: 323.9;Oligodendrocytes: 316.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" 1 Nucleoplasm "CAB020834: , HPA068605: AB_2732116, HPA071780: " "unprognostic (4.62e-2)" "unprognostic (1.96e-3)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.78e-3)" "unprognostic (2.36e-3)" "unprognostic (6.01e-2)" "unprognostic (1.01e-2)" "unprognostic (3.04e-3)" "unprognostic (6.56e-2)" "unprognostic (9.81e-2)" "unprognostic (4.39e-3)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 75.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.3;Leydig cells: 185.3;Peritubular cells: 264.8;Skeletal myocytes: 169.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.7;naive B-cell: 17.1" "Lineage enriched" "Detected in many" 19 "B-cells: 57.7" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" SSR1 TRAPA ENSG00000124783 "Signal sequence receptor subunit 1" P43307 6 7268306-7347446 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011276, HPA017062" Enhanced Supported "Endoplasmic reticulum" NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "HPA011276: AB_1857503, HPA017062: AB_1857505" "unprognostic (2.27e-1)" "unprognostic (2.10e-1)" "unprognostic (5.98e-3)" "unprognostic (1.57e-2)" "unprognostic (3.10e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (7.83e-2)" "unprognostic (2.27e-2)" "unprognostic (4.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.79e-6)" "unprognostic (3.17e-1)" "unprognostic (2.56e-2)" "unprognostic (6.51e-3)" "unprognostic (2.19e-2)" SSR3 TRAPG ENSG00000114850 "Signal sequence receptor subunit 3" Q9UNL2 3 156539553-156555149 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 1053.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014906 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 77: Plasma cells - Protein processing" 1 "HPA014906: AB_2195736" "unprognostic (4.11e-1)" "unprognostic (3.50e-1)" "unprognostic (5.49e-2)" "unprognostic (5.46e-2)" "unprognostic (5.74e-2)" "prognostic unfavorable (3.43e-4)" "prognostic unfavorable (4.46e-7)" "unprognostic (1.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.87e-2)" "unprognostic (2.19e-3)" "unprognostic (6.68e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.23e-2)" "unprognostic (2.92e-2)" "unprognostic (1.39e-2)" "unprognostic (8.29e-2)" SSR4 TRAPD ENSG00000180879 "Signal sequence receptor subunit 4" P51571 X 153793516-153798499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 3019.5" "Group enriched" "Detected in all" 4 "Late spermatids: 1743.0;Plasma cells: 6157.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045209 Enhanced Supported "Endoplasmic reticulum" NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "HPA045209: AB_10961407" "unprognostic (3.56e-2)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" "prognostic favorable (1.76e-4)" "unprognostic (8.74e-2)" "unprognostic (5.57e-2)" "unprognostic (7.99e-2)" "unprognostic (4.58e-2)" "unprognostic (2.10e-1)" "unprognostic (5.04e-3)" "unprognostic (5.74e-3)" "unprognostic (8.76e-2)" "prognostic unfavorable (5.51e-6)" "unprognostic (8.18e-2)" "unprognostic (2.24e-1)" "unprognostic (6.01e-2)" "unprognostic (5.33e-2)" SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2;intestine: 13.4;stomach 1: 21.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.0;Enteroendocrine cells: 25.1;Gastric mucus-secreting cells: 18.3;Oligodendrocyte precursor cells: 22.6;Paneth cells: 11.1;Proximal enterocytes: 10.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 25: Small intestine - Absorption" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 37.4;Enteroendocrine cells: 46.9;Horizontal cells: 76.2;Mucus glandular cells: 26.7;Smooth muscle cells: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Neuroblastoma: 18.2" "Breast - Endothelial cells, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 48: Smooth muscle cells - Signal transduction" 3 Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;lymphoid tissue: 10.8;testis: 7.6" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Sertoli cells: 10.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Cancer enriched" "Detected in some" 5 "Myeloma: 23.4" "Adipose visceral - Mesothelial cells, Breast - Plasma cells, Kidney - Podocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 3 "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" SSTR4 ENSG00000132671 "Somatostatin receptor 4" P31391 20 23035312-23039237 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" HPA064252 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" 1 "HPA064252: AB_2685227" SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1072747-1081454 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.4;heart muscle: 6.7;kidney: 2.8;pituitary gland: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 5.6" "Heart muscle - Cardiomyocytes, Pancreas - Beta cells" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" 3 "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" ST14 "CAP3, HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 140.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 375.6;Intestinal goblet cells: 175.1;Paneth cells: 164.2;Proximal enterocytes: 201.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 19.4" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Colon enterocytes, Heart muscle - Macrophages, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 82.4;Langerhans cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.9;tongue: 79.6" "Cell type enhanced" "Detected in many" "Astrocytes: 56.7;Excitatory neurons: 91.3;Inhibitory neurons: 115.2;Microglial cells: 54.6;Oligodendrocyte precursor cells: 62.7;Oligodendrocytes: 61.6;Rod photoreceptor cells: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 1032.1" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 112.4;neutrophil: 72.1;plasmacytoid DC: 93.9" "Group enriched" "Detected in many" 12 "dendritic cells: 93.9;granulocytes: 112.4" "Cancer enriched" "Detected in all" 4 "skin cancer: 242.2" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" Enzyme NA NA 15000 "Cluster 41: Basophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA049827: AB_2680900" "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 129.0;Oligodendrocytes: 100.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 28.1" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" ST3GAL6 "SIAT10, ST3GALVI" ENSG00000064225 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" Q9Y274 3 98732236-98821201 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.8;Extravillous trophoblasts: 79.0;Hepatocytes: 77.9;Langerhans cells: 83.9;Melanocytes: 77.3;Microglial cells: 127.9;Oligodendrocyte precursor cells: 160.8" "Cancer enriched" "Detected in many" 5 "melanoma: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 41.3;neutrophil: 50.9" "Group enriched" "Detected in many" 123 "dendritic cells: 19.8;granulocytes: 50.9;monocytes: 14.6" "Group enriched" "Detected in many" 5 "Myeloma: 32.4;Neuroblastoma: 15.7;skin cancer: 37.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018792 Approved NA NA 5800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA018792: AB_10964349" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (4.17e-2)" "unprognostic (5.20e-3)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (2.30e-3)" "unprognostic (2.40e-1)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (4.32e-1)" "unprognostic (3.91e-3)" "unprognostic (6.15e-3)" "unprognostic (9.44e-2)" "unprognostic (9.47e-3)" "unprognostic (6.79e-4)" ST6GAL2 "KIAA1877, SIAT2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.9;thyroid gland: 28.2" "Group enriched" "Detected in many" 5 "Astrocytes: 55.7;Excitatory neurons: 75.9;Inhibitory neurons: 42.7;Oligodendrocyte precursor cells: 88.2" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 15.8" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: AB_1857528" "unprognostic (2.08e-1)" "unprognostic (5.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (6.44e-3)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-4)" "unprognostic (4.56e-3)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (7.01e-4)" "unprognostic (4.70e-4)" "unprognostic (4.06e-2)" "unprognostic (2.83e-1)" "unprognostic (2.07e-2)" ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643786 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 58.9;intestine: 189.6;stomach 1: 63.2" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 724.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 8.9;naive CD4 T-cell: 3.4" "Lineage enriched" "Detected in single" 33 "T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 3500000 "Cluster 31: T-cells - T-cell receptor" "Cluster 45: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: AB_1857529" "unprognostic (4.59e-2)" "unprognostic (8.60e-3)" "unprognostic (5.32e-3)" "unprognostic (1.86e-3)" "unprognostic (6.31e-3)" "prognostic favorable (2.54e-5)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.58e-2)" "unprognostic (8.64e-3)" "unprognostic (2.81e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (5.87e-3)" "unprognostic (5.58e-2)" ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Microglial cells: 871.4;Oligodendrocytes: 650.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Neuroblastoma: 13.8;skin cancer: 12.1;testis cancer: 7.6;thyroid cancer: 3.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" ST6GALNAC4 "SIAT3C, SIAT7D, ST6GALNACIV" ENSG00000136840 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4" Q9H4F1 9 127907886-127917041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 75.6;dendritic cells: 97.0;Erythroid cells: 90.3;Plasma cells: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "plasmacytoid DC: 234.3" "Lineage enriched" "Detected in all" 9 "dendritic cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009042 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 18: Non-specific - Ribosome" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" Nucleoplasm "HPA009042: AB_1079963" "unprognostic (2.05e-3)" "unprognostic (2.32e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-2)" "unprognostic (3.18e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (1.62e-2)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.04e-1)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.30e-3)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (2.03e-2)" ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.4;Excitatory neurons: 11.1;Inhibitory neurons: 10.2;NK-cells: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018890, HPA072757" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 2 Cytosol "HPA018890: AB_1857531, HPA072757: " "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 174.6;Early spermatids: 121.0;Excitatory neurons: 185.0;Inhibitory neurons: 168.6;Oligodendrocyte precursor cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 35: Non-specific - DNA binding" "Cluster 39: Non-specific - Transcription" "Cluster 47: Astrocytes - Unknown function" 1 Nucleoplasm Cytosol "HPA038325: AB_10671740, HPA038326: AB_10672644" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (4.70e-2)" "unprognostic (1.09e-1)" "unprognostic (8.18e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "prognostic favorable (3.39e-5)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" ST7L "FAM4B, FLJ20284, ST7R, STLR" ENSG00000007341 "Suppression of tumorigenicity 7 like" Q8TDW4 1 112523514-112620825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 35.0" "Cell type enhanced" "Detected in all" "Early spermatids: 189.3;Late spermatids: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042324, HPA075418" Uncertain Approved Centrosome NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 21: Testis - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Late spermatids - Unknown function" Centrosome "HPA042324: AB_10794273, HPA075418: AB_2686749" "unprognostic (2.99e-2)" "unprognostic (1.07e-2)" "prognostic favorable (8.34e-5)" "prognostic unfavorable (8.96e-4)" "unprognostic (3.30e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-6)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.16e-4)" "prognostic favorable (3.04e-5)" "unprognostic (2.98e-2)" "unprognostic (6.91e-2)" "unprognostic (5.72e-2)" "unprognostic (4.12e-3)" "unprognostic (3.68e-2)" "unprognostic (3.26e-2)" "unprognostic (3.27e-2)" ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 128.6;Inhibitory neurons: 146.2;Oligodendrocyte precursor cells: 185.8;Oocytes: 117.6" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 4.3;skin cancer: 10.6" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA026775: AB_1857534" "unprognostic (1.98e-1)" "unprognostic (5.76e-3)" "unprognostic (1.79e-1)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-3)" "unprognostic (1.76e-2)" "unprognostic (1.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.99e-1)" "unprognostic (6.37e-3)" "unprognostic (2.80e-2)" "unprognostic (1.07e-8)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (5.28e-2)" "unprognostic (3.16e-2)" ST8SIA3 SIAT8C ENSG00000177511 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" O43173 18 57352557-57371731 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 7.9;retina: 7.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 24.2;Excitatory neurons: 72.4;Horizontal cells: 40.9;Inhibitory neurons: 54.2;Oligodendrocyte precursor cells: 20.8" "Group enriched" "Detected in some" 11 "glioma: 0.9;pancreatic cancer: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 9.4;thyroid cancer: 4.1" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063398, HPA066783" Enhanced Supported "Golgi apparatus" No NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" "HPA063398: AB_2685004, HPA066783: AB_2685721" "unprognostic (1.75e-1)" "unprognostic (7.85e-2)" "unprognostic (1.41e-2)" "unprognostic (5.50e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.82e-1)" ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 11.8;brain: 27.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 102.6;Inhibitory neurons: 72.3;Oligodendrocyte precursor cells: 30.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 7.7" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 429.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 116.5;Fibroblasts: 125.5;Hofbauer cells: 146.4;Kupffer cells: 201.1;Macrophages: 214.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.5;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.5" "Cancer enriched" "Detected in single" 65 "Leukemia: 14.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" STAB2 "DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2" ENSG00000136011 "Stabilin 2" Q8WWQ8 12 103587273-103766719 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 64.3" "Cell type enhanced" "Detected in some" "Endothelial cells: 35.0;Fibroblasts: 19.5;Kupffer cells: 20.8;Late spermatids: 11.3;Lymphatic endothelial cells: 78.6;Oocytes: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Liver - Sinusoid Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026871, HPA072699" Enhanced Supported Cytosol NA NA 1200000 "Cluster 47: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Cytosol "HPA026871: AB_1857536, HPA072699: " "unprognostic (5.66e-3)" "unprognostic (7.51e-2)" "unprognostic (3.31e-1)" "unprognostic (3.84e-2)" "unprognostic (8.47e-2)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (5.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.24e-2)" "unprognostic (1.05e-1)" "unprognostic (9.72e-4)" "unprognostic (1.37e-2)" "unprognostic (5.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-1)" STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 3 "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 3 Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 81.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 148.3;Club cells: 62.9;Ionocytes: 146.2;Mesothelial cells: 87.3;Prostatic glandular cells: 180.1" "Cancer enriched" "Detected in all" 6 "prostate cancer: 94.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 177.2" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" HPA030985 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA030985: AB_2673686" "unprognostic (2.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.21e-3)" "unprognostic (9.20e-3)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" "unprognostic (6.74e-3)" "unprognostic (6.36e-2)" "unprognostic (6.45e-3)" "unprognostic (8.31e-3)" "unprognostic (3.79e-1)" "unprognostic (2.60e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-1)" "unprognostic (6.09e-2)" "unprognostic (1.38e-1)" STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 123.5" "Cell type enriched" "Detected in many" 9 "Prostatic glandular cells: 640.5" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 90.6" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 184.9;parathyroid gland: 76.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" 1 Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 109.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 161.5;Club cells: 154.6;Ionocytes: 97.6;Leydig cells: 114.1;Mucus glandular cells: 120.2;Sertoli cells: 204.0;Smooth muscle cells: 296.6" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Region enriched" "Detected in all" 4 "choroid plexus: 39.4" "Immune cell enriched" "Detected in some" 12 "neutrophil: 161.9" "Lineage enriched" "Detected in many" 12 "granulocytes: 161.9" "Cancer enriched" "Detected in many" 6 "cervical cancer: 90.3" "Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.8;lymphoid tissue: 8.6" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 12.1;Spermatocytes: 17.0;Spermatogonia: 12.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028388 Approved Nucleoplasm,Centrosome NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Non-specific - Cell proliferation" 3 "Nucleoplasm, Centrosome" "HPA028388: " "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" STIM1 "D11S4896E, GOK" ENSG00000167323 "Stromal interaction molecule 1" Q13586 11 3854527-4093210 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011088, HPA012123, CAB037128, CAB037288" Enhanced Enhanced "Endoplasmic reticulum" NA NA 1900000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 12: Squamous epithelial cells - Keratinization" 20 "Endoplasmic reticulum" "CAB037128: AB_1079007, CAB037288: AB_1079008, HPA011088: AB_1849884, HPA012123: AB_1849882" "unprognostic (2.06e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.13e-2)" "unprognostic (4.12e-1)" "unprognostic (3.43e-1)" "unprognostic (1.59e-1)" "unprognostic (2.25e-1)" "unprognostic (7.41e-2)" "unprognostic (1.86e-1)" "unprognostic (2.88e-2)" "unprognostic (9.35e-2)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" STIM2 ENSG00000109689 "Stromal interaction molecule 2" Q9P246 4 26857601-27025381 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 61.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 181.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036933, CAB037196, HPA057511" Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 55: Non-specific - Transcription" 1 "CAB037196: AB_1841195, HPA036933: AB_2675391, HPA057511: AB_2683453" "unprognostic (7.09e-2)" "unprognostic (8.80e-3)" "unprognostic (1.60e-3)" "unprognostic (2.58e-2)" "unprognostic (2.83e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (3.97e-5)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "prognostic favorable (5.01e-4)" "unprognostic (6.81e-2)" "unprognostic (1.45e-2)" "unprognostic (2.60e-2)" "unprognostic (7.55e-2)" "unprognostic (3.17e-1)" "unprognostic (2.17e-3)" STIMATE "MGC52022, TMEM110" ENSG00000213533 "STIM activating enhancer" Q86TL2 3 52836219-52897548 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 14.1;Hepatocytes: 20.3;Late spermatids: 16.4;Oocytes: 25.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Non-specific - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "HPA051855: AB_2681639" "unprognostic (1.45e-1)" "unprognostic (7.93e-3)" "unprognostic (2.19e-1)" "unprognostic (2.49e-2)" "unprognostic (2.29e-3)" "unprognostic (3.87e-2)" "unprognostic (9.31e-2)" "unprognostic (7.55e-4)" "unprognostic (3.34e-1)" "unprognostic (6.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.33e-2)" "unprognostic (1.00e-1)" "unprognostic (1.76e-1)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" STIMATE-MUSTN1 TMEM110-MUSTN1 ENSG00000248592 "STIMATE-MUSTN1 readthrough" 3 52833121-52897562 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 14.6;skeletal muscle: 9.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.1;Cone photoreceptor cells: 1.7;Gastric mucus-secreting cells: 1.8;Plasma cells: 1.3;Smooth muscle cells: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" Cytosol "HPA051855: AB_2681639" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (5.95e-2)" "unprognostic (7.28e-2)" "unprognostic (5.35e-2)" "unprognostic (3.11e-4)" "unprognostic (4.73e-2)" "unprognostic (2.66e-2)" "unprognostic (1.59e-2)" "unprognostic (2.51e-2)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.01e-6)" "unprognostic (5.49e-2)" "unprognostic (7.31e-2)" "unprognostic (4.55e-2)" "unprognostic (5.09e-5)" STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 111.7;Endothelial cells: 99.6;Lymphatic endothelial cells: 103.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 21.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Smooth muscle cells, Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534, CAB080401" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 22 Cytosol Nucleoplasm "CAB080401: , HPA038116: AB_2675841, HPA038534: AB_2676067" "unprognostic (1.45e-1)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-2)" "unprognostic (1.71e-2)" "unprognostic (7.66e-2)" "unprognostic (2.77e-2)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" "unprognostic (5.69e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.59e-8)" "unprognostic (9.18e-3)" "unprognostic (4.14e-2)" "unprognostic (4.45e-2)" "unprognostic (1.34e-1)" STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 224.6;B-cells: 252.4;NK-cells: 277.9;T-cells: 284.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 372.2;lymphoid tissue: 110.6" "Cell type enhanced" "Detected in many" "B-cells: 242.1;granulocytes: 336.2;monocytes: 764.7;NK-cells: 289.2;Schwann cells: 288.1;T-cells: 389.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 74.3" "Testis - Early spermatids, Testis - Spermatocytes" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" "HPA034858, HPA073120" Enhanced Supported Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm "HPA034858: AB_10670981, HPA073120: " "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.9;Excitatory neurons: 21.3;Spermatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 7 Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385924 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.7;Late spermatids: 228.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.3" "Group enriched" "Detected in all" 5 "granulocytes: 25.3;monocytes: 12.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Late spermatids - Spermatogenesis" 2 Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 431.6;Alveolar cells type 1: 393.3;Endothelial cells: 371.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Neutrophils, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 120 "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" STOML1 "FLJ36370, hUNC-24, SLP-1, STORP" ENSG00000067221 "Stomatin like 1" Q9UBI4 15 73978926-73994622 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042353 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "HPA042353: AB_10797387" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (7.76e-2)" "unprognostic (4.54e-3)" "unprognostic (1.39e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.78e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" "unprognostic (2.30e-3)" "unprognostic (2.26e-3)" "unprognostic (2.14e-1)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.67e-2)" STOML3 "Epb7.2l, SRO" ENSG00000133115 "Stomatin like 3" Q8TAV4 13 38965925-38990859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "fallopian tube: 33.8" "Cell type enriched" "Detected in some" 9 "Ciliated cells: 88.7" "Group enriched" "Detected in some" 4 "endometrial cancer: 2.4;lung cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Region enriched" "Detected in many" 6 "olfactory bulb: 23.6" "Low region specificity" "Detected in all" "HPA012892, HPA071011" Enhanced Supported "Plasma membrane" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 4 "Plasma membrane" "HPA012892: AB_1857610, HPA071011: AB_2732169" "unprognostic (2.64e-1)" "unprognostic (1.91e-2)" "prognostic favorable (1.49e-4)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "unprognostic (4.24e-2)" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.14e-1)" "unprognostic (1.07e-2)" "unprognostic (1.35e-2)" "unprognostic (3.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.22e-1)" STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.8" "Cell type enhanced" "Detected in some" "Club cells: 21.7;Endometrial stromal cells: 41.8;Extravillous trophoblasts: 11.7;Ionocytes: 9.9;Syncytiotrophoblasts: 27.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" STRN4 "PPP2R6C, ZIN" ENSG00000090372 "Striatin 4" Q9NRL3 19 46719511-46746994 "Predicted intracellular proteins, Predicted membrane proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043051, HPA043527, HPA056706" Supported Approved Cytosol NA NA 32000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 57: Platelets - Hemostasis" 4 Cytosol "HPA043051: AB_2678290, HPA043527: AB_10959664, HPA056706: AB_2683214" "unprognostic (3.57e-2)" "unprognostic (7.96e-2)" "unprognostic (2.13e-2)" "unprognostic (7.39e-2)" "unprognostic (1.81e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (6.06e-8)" "unprognostic (8.31e-3)" "unprognostic (5.34e-2)" "prognostic unfavorable (2.98e-4)" "unprognostic (1.56e-1)" "unprognostic (9.41e-3)" "unprognostic (4.86e-3)" "unprognostic (6.74e-2)" "unprognostic (4.06e-2)" "unprognostic (6.04e-2)" "unprognostic (1.84e-1)" STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" X 7147237-7804358 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 25.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.7;Excitatory neurons: 31.1;Inhibitory neurons: 37.8;Syncytiotrophoblasts: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 35.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3 oligosaccharyltransferase complex catalytic subunit A" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 379.5" "Cell type enhanced" "Detected in many" "Plasma cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved NA NA 23000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 61: Plasma cells - Immunoglobulins & histones" 7 "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favorable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 262.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 17000 "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 77: Plasma cells - Protein processing" 4 "Endoplasmic reticulum" "HPA036448: AB_2675129, HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" STUM "C1orf95, DKFZp761P211" ENSG00000203685 "Stum, mechanosensory transduction mediator homolog" Q69YW2 1 226548764-226609230 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 47.2;intestine: 15.2" "Cell type enhanced" "Detected in some" "Astrocytes: 19.2;Enteroendocrine cells: 7.6;Excitatory neurons: 18.5;Granulosa cells: 7.7;Inhibitory neurons: 6.5;Oligodendrocyte precursor cells: 12.3;Sertoli cells: 8.2;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "medulla oblongata: 551.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.4;lung cancer: 1.8" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074381 Approved Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" 1 Cytosol "HPA074381: AB_2732253" "unprognostic (3.23e-3)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (4.09e-2)" "unprognostic (2.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.41e-3)" "unprognostic (3.07e-1)" "unprognostic (5.15e-2)" "unprognostic (7.62e-2)" "unprognostic (3.28e-2)" "prognostic favorable (6.40e-4)" "unprognostic (1.14e-2)" "unprognostic (9.04e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-3)" STX10 "hsyn10, SYN10" ENSG00000104915 "Syntaxin 10" O60499 19 13144058-13150383 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035303, HPA056439" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus, Vesicles" "HPA035303: AB_10671932, HPA056439: AB_2683135" "unprognostic (1.72e-2)" "unprognostic (2.26e-2)" "unprognostic (1.62e-2)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-3)" "prognostic favorable (8.26e-4)" "unprognostic (4.09e-1)" "unprognostic (3.66e-2)" "unprognostic (4.57e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (2.39e-3)" "unprognostic (7.95e-2)" "unprognostic (2.23e-1)" "unprognostic (2.98e-2)" STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 33 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" STX16 "hsyn16, SYN-16, SYN16" ENSG00000124222 "Syntaxin 16" O14662 20 58651253-58679526 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041019, HPA042033" Uncertain Enhanced Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 55: Non-specific - Transcription" 4 Vesicles "HPA041019: AB_10964273, HPA042033: AB_10963935" "unprognostic (7.52e-2)" "unprognostic (1.91e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (4.18e-4)" "unprognostic (7.32e-2)" "unprognostic (5.11e-2)" "unprognostic (3.51e-2)" "unprognostic (2.80e-3)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (5.89e-2)" STX17 FLJ20651 ENSG00000136874 "Syntaxin 17" P56962 9 99906654-99974534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001204 Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" 8 "Nucleoli, Cytosol" "HPA001204: AB_1080118" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (6.71e-2)" "unprognostic (1.88e-1)" "unprognostic (2.36e-1)" "unprognostic (1.70e-2)" "unprognostic (9.75e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.62e-5)" "unprognostic (9.48e-2)" "unprognostic (4.32e-2)" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 115.6" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 251.5" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Fallopian tube - Tissue development" "Cluster 36: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Endoplasmic reticulum, Plasma membrane" "HPA003019: AB_1857622" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.84e-4)" "prognostic favorable (6.33e-8)" "unprognostic (4.21e-1)" "unprognostic (6.77e-2)" "unprognostic (6.17e-3)" "unprognostic (2.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "prognostic favorable (7.03e-4)" "unprognostic (1.92e-2)" "unprognostic (1.55e-1)" "unprognostic (7.44e-2)" "prognostic favorable (4.69e-4)" STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 174.8;pituitary gland: 95.9" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.5;Excitatory neurons: 58.6;Pancreatic endocrine cells: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Alpha cells, Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "amygdala: 246.4;basal ganglia: 93.9;cerebral cortex: 354.5;hippocampal formation: 229.2;white matter: 116.1" "Group enriched" "Detected in all" 8 "amygdala: 48.7;cerebral cortex: 134.1;hippocampal formation: 113.2" "CAB008372, HPA069176" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" Transport NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 96 Vesicles "Nuclear membrane" "CAB008372: AB_592786, HPA069176: AB_2686098" "unprognostic (5.12e-3)" "prognostic unfavorable (3.63e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.02e-8)" "unprognostic (1.11e-2)" "unprognostic (6.97e-2)" "unprognostic (3.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.70e-3)" "unprognostic (4.18e-6)" "unprognostic (2.65e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-3)" "unprognostic (6.20e-2)" STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 145.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 35.6;Horizontal cells: 52.2;Inhibitory neurons: 29.8;Late spermatids: 14.2" "Cancer enriched" "Detected in some" 7 "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.9" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 21 Vesicles "Nuclear membrane" "CAB079008: , HPA069176: AB_2686098" "unprognostic (1.43e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-4)" "unprognostic (3.90e-3)" "unprognostic (3.98e-2)" "unprognostic (1.90e-2)" "unprognostic (2.21e-3)" "unprognostic (2.53e-2)" "unprognostic (1.72e-1)" "unprognostic (3.72e-3)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (1.57e-2)" STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839254 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 139.9;Late spermatids: 124.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Late spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" STX3 STX3A ENSG00000166900 "Syntaxin 3" Q13277 11 59713456-59805882 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 303.5" "Cell type enhanced" "Detected in all" "Bipolar cells: 321.4;Cone photoreceptor cells: 350.0;Rod photoreceptor cells: 354.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 42.5;eosinophil: 74.2;neutrophil: 60.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002191, HPA069176" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Bipolar cells - Visual perception" 33 Vesicles "Nuclear membrane" "HPA002191: AB_1080165, HPA069176: AB_2686098" "unprognostic (2.24e-2)" "unprognostic (1.97e-2)" "unprognostic (7.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.84e-2)" "unprognostic (2.36e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (1.64e-1)" "unprognostic (3.00e-1)" "unprognostic (7.71e-3)" "unprognostic (2.07e-2)" "unprognostic (5.55e-2)" "prognostic favorable (1.14e-6)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" "unprognostic (4.02e-2)" "unprognostic (1.17e-2)" STX4 "p35-2, STX4A" ENSG00000103496 "Syntaxin 4" Q12846 16 31032889-31042975 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001330 Approved Approved "Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 47: Spleen - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 37 "Plasma membrane" "HPA001330: AB_1080167" "unprognostic (2.31e-3)" "prognostic favorable (3.65e-4)" "unprognostic (3.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.74e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "unprognostic (5.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.01e-2)" "unprognostic (3.12e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.88e-9)" "unprognostic (6.90e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.26e-2)" STX5 "SED5, STX5A" ENSG00000162236 "Syntaxin 5" Q13190 11 62806860-62832051 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 159.7;Syncytiotrophoblasts: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001358 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 26 "Golgi apparatus" Nucleoplasm "HPA001358: AB_1080119" "unprognostic (3.51e-2)" "unprognostic (4.23e-2)" "unprognostic (1.79e-1)" "unprognostic (1.91e-3)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-2)" "unprognostic (3.30e-1)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (1.67e-2)" "unprognostic (3.42e-2)" "unprognostic (2.79e-1)" "unprognostic (2.86e-2)" "unprognostic (8.22e-3)" STX6 ENSG00000135823 "Syntaxin 6" O43752 1 180972712-181023121 "Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038557, HPA038558" Approved Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 80: Non-specific - Endocytosis" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 24 "Golgi apparatus" Nucleoplasm "HPA038557: AB_2676082, HPA038558: AB_10672716" "unprognostic (1.11e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.09e-3)" "unprognostic (2.23e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.12e-1)" "unprognostic (6.12e-2)" "unprognostic (4.48e-3)" "unprognostic (4.18e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.93e-8)" "unprognostic (2.59e-1)" "unprognostic (1.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" STX7 ENSG00000079950 "Syntaxin 7" O15400 6 132445867-132513198 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 53.6;classical monocyte: 51.6;eosinophil: 49.2;intermediate monocyte: 58.1;memory B-cell: 86.2;myeloid DC: 61.6;naive B-cell: 107.2;neutrophil: 83.5;non-classical monocyte: 61.9;plasmacytoid DC: 74.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001467, CAB062564" Enhanced Supported Lysosomes NA NA 380000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 73: B-cells - B-cell function" 36 Lysosomes "CAB062564: AB_2665605, HPA001467: AB_1857623" "unprognostic (1.91e-3)" "unprognostic (1.06e-3)" "unprognostic (2.67e-2)" "unprognostic (7.95e-3)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (4.52e-2)" "unprognostic (4.46e-1)" "unprognostic (4.19e-2)" "unprognostic (2.84e-1)" "unprognostic (2.79e-1)" "unprognostic (1.65e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (1.67e-1)" "unprognostic (8.42e-2)" STX8 CARB ENSG00000170310 "Syntaxin 8" Q9UNK0 17 9250471-9576591 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Late spermatids: 939.3;Oocytes: 958.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001540 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Testis - Spermatid development" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 58 Vesicles Cytosol "HPA001540: AB_1080168" "unprognostic (8.68e-2)" "unprognostic (2.29e-2)" "unprognostic (2.53e-1)" "unprognostic (4.14e-3)" "unprognostic (3.36e-1)" "unprognostic (1.58e-2)" "unprognostic (6.91e-2)" "unprognostic (1.19e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (1.86e-3)" "unprognostic (2.54e-1)" "unprognostic (1.45e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.77e-2)" "unprognostic (1.51e-1)" STXBP1 "hUNC18, MUNC18-1, nSec1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 274.3;retina: 196.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 118.5;Cone photoreceptor cells: 185.2;Excitatory neurons: 235.1;Horizontal cells: 120.9;Inhibitory neurons: 150.7;Rod photoreceptor cells: 179.2" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 120.7" "Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 31: T-cells - T-cell receptor" "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Photoreceptor cells - Visual perception" 16 "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.5;stomach 1: 17.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.5;Excitatory neurons: 19.9;Gastric mucus-secreting cells: 15.9;Intestinal goblet cells: 14.3;Prostatic glandular cells: 20.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 38.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.2;Hofbauer cells: 18.4;Kupffer cells: 18.8;Langerhans cells: 9.7;Macrophages: 13.0;monocytes: 9.8;Proximal tubular cells: 35.0;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.9;Rhabdoid: 14.1" "Breast - Endothelial cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" CAB022745 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" SUCO "C1orf9, CH1, OPT, SLP1" ENSG00000094975 "SUN domain containing ossification factor" Q9UBS9 1 172532349-172611833 "Predicted membrane proteins" Osteogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 82.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047251 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA 45000 "Cluster 32: Basophils - Transcription" "Cluster 6: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Nucleoli fibrillar center, Cytosol" "HPA047251: AB_2679999" "unprognostic (1.28e-2)" "unprognostic (6.38e-3)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (4.57e-2)" "unprognostic (1.92e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" "unprognostic (7.05e-2)" SUN1 "FLJ12407, KIAA0810, UNC84A" ENSG00000164828 "Sad1 and UNC84 domain containing 1" O94901 7 816615-896435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Meiosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 329.3;Late spermatids: 583.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008346, HPA008461" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 4 "Nuclear membrane" "HPA008346: AB_1080462, HPA008461: AB_1080461" "unprognostic (2.70e-2)" "unprognostic (1.51e-2)" "unprognostic (1.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.25e-1)" "unprognostic (2.57e-3)" "unprognostic (1.82e-1)" "unprognostic (1.67e-1)" "unprognostic (4.57e-2)" "unprognostic (3.32e-2)" "unprognostic (1.69e-1)" "unprognostic (8.10e-2)" "unprognostic (1.08e-2)" "unprognostic (1.47e-2)" "unprognostic (4.63e-2)" "unprognostic (1.34e-1)" "unprognostic (9.33e-2)" SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38733290-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 178.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" 10 "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" SUN3 "MGC33329, SUNC1" ENSG00000164744 "Sad1 and UNC84 domain containing 3" Q8TAQ9 7 47987148-48029119 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 336 "testis: 40.4" "Group enriched" "Detected in some" 12 "Early spermatids: 597.3;Late spermatids: 174.3" "Cancer enriched" "Detected in single" 4 "testis cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA076890 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 4: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "HPA076890: " "unprognostic (5.11e-2)" "unprognostic (4.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-4)" "unprognostic (2.31e-2)" "unprognostic (5.62e-2)" "unprognostic (1.35e-2)" "unprognostic (2.24e-2)" "unprognostic (1.59e-5)" "unprognostic (4.88e-1)" "unprognostic (1.47e-1)" "unprognostic (2.65e-1)" "unprognostic (1.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.48e-1)" "unprognostic (2.58e-1)" SUN5 "dJ726C3.1, SPAG4L, TSARG4" ENSG00000167098 "Sad1 and UNC84 domain containing 5" Q8TC36 20 32983773-33004433 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 436 "testis: 43.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 566.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048529 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA048529: AB_2680428" SURF1 SHY1 ENSG00000148290 "SURF1 cytochrome c oxidase assembly factor" Q15526 9 133351758-133356676 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033946 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 1 "CAB033946: AB_2302648" "unprognostic (1.87e-1)" "unprognostic (7.76e-3)" "unprognostic (1.34e-2)" "unprognostic (4.26e-3)" "unprognostic (3.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.68e-2)" "unprognostic (3.00e-1)" "unprognostic (4.75e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "prognostic favorable (6.92e-9)" "unprognostic (3.91e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.98e-1)" SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 276.2;Syncytiotrophoblasts: 350.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 77: Plasma cells - Protein processing" 5 "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" SUSD1 DKFZP761E1824 ENSG00000106868 "Sushi domain containing 1" Q6UWL2 9 112040783-112175297 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 27.4;Kupffer cells: 28.8;monocytes: 29.1;Oligodendrocyte precursor cells: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;plasmacytoid DC: 44.3" "Group enriched" "Detected in many" 5 "dendritic cells: 44.3;granulocytes: 11.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048554 Approved Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA 2300000 "Cluster 29: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm "HPA048554: AB_2680439" "unprognostic (2.25e-1)" "unprognostic (4.02e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (9.29e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "prognostic favorable (3.63e-6)" "unprognostic (2.14e-3)" "unprognostic (8.38e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 189.3;Alveolar cells type 2: 142.2;Proximal enterocytes: 134.8" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 65.6;Rhabdoid: 35.5" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatic stellate cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 7 "spinal cord: 14.4" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" 2 "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" SUSD3 MGC26847 ENSG00000157303 "Sushi domain containing 3" Q96L08 9 93058688-93085133 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.9;testis: 75.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 198.2;Hepatocytes: 70.8;Mesothelial cells: 61.2;Oocytes: 62.5;Ovarian stromal cells: 49.9;Secretory cells: 54.1;Sertoli cells: 73.4" "Cancer enhanced" "Detected in all" "breast cancer: 50.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "breast cancer: 23.6;Leukemia: 31.6;lymphoma: 46.4;Myeloma: 22.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042310 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" 22 "HPA042310: AB_10796902" "prognostic favorable (5.13e-4)" "unprognostic (5.42e-2)" "unprognostic (3.65e-1)" "unprognostic (8.34e-3)" "unprognostic (9.06e-2)" "unprognostic (2.84e-2)" "unprognostic (2.94e-2)" "unprognostic (7.41e-3)" "unprognostic (5.06e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (3.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.39e-3)" "unprognostic (5.33e-2)" SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0;esophagus: 49.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.7;Granulosa cells: 73.3;Inhibitory neurons: 85.9;Oligodendrocyte precursor cells: 95.3;Squamous epithelial cells: 78.7;Suprabasal keratinocytes: 49.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cancer enhanced" "Detected in many" "breast cancer: 16.1" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" "Complement pathway" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 14.9;Inhibitory neurons: 10.1;Oligodendrocyte precursor cells: 57.5;Sertoli cells: 10.9;Smooth muscle cells: 33.9" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Fibroblast_2, Testis - Spermatogonia, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" SUSD6 KIAA0247 ENSG00000100647 "Sushi domain containing 6" Q92537 14 69611596-69715144 "Predicted membrane proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 102.9;monocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030464 Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 29: Monocytes - Innate immune response" 7 Nucleoplasm "Intermediate filaments" "HPA030464: AB_10601128" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (7.34e-2)" "unprognostic (1.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.46e-2)" "unprognostic (2.17e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-1)" "unprognostic (3.66e-3)" "unprognostic (1.10e-2)" "unprognostic (6.70e-2)" "prognostic favorable (2.16e-4)" "unprognostic (1.10e-2)" "unprognostic (5.35e-2)" "unprognostic (1.30e-2)" "unprognostic (2.34e-1)" SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 118.3;parathyroid gland: 46.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.7;Excitatory neurons: 61.3;Horizontal cells: 163.0;Inhibitory neurons: 102.7" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 54.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 28.2;retina: 54.6" "Group enriched" "Detected in some" 5 "Bipolar cells: 130.3;Cone photoreceptor cells: 146.1;Excitatory neurons: 439.8;Rod photoreceptor cells: 144.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;lung cancer: 1.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" SV2C ENSG00000122012 "Synaptic vesicle glycoprotein 2C" Q496J9 5 76083383-76353939 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 16.2;retina: 4.1" "Group enriched" "Detected in some" 6 "Excitatory neurons: 82.6;Granulosa cells: 68.0;Horizontal cells: 37.1;Inhibitory neurons: 78.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cancer enriched" "Detected in single" 10 "Neuroblastoma: 9.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040722, HPA040770" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Vesicles" "HPA040722: AB_10795624, HPA040770: AB_10805828" "unprognostic (7.91e-2)" "unprognostic (2.33e-1)" "unprognostic (2.05e-1)" "unprognostic (2.41e-2)" "unprognostic (1.07e-1)" "unprognostic (9.93e-2)" "unprognostic (1.09e-2)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 25.6;pituitary gland: 7.2;retina: 12.6" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 56.1;Early spermatids: 50.3;Excitatory neurons: 68.0;Inhibitory neurons: 72.5;Late spermatids: 129.8" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.6" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 1 "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" SVOPL MGC46715 ENSG00000157703 "SVOP like" Q8N434 7 138594285-138701362 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.8" "Group enriched" "Detected in some" 5 "granulocytes: 32.8;Oocytes: 61.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA018035 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "HPA018035: AB_2197028" "unprognostic (6.70e-5)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (2.49e-1)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "unprognostic (7.69e-3)" "unprognostic (2.59e-3)" "unprognostic (7.16e-2)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (5.03e-3)" "unprognostic (2.22e-4)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (8.51e-2)" SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.8;pancreas: 136.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.8;Inhibitory neurons: 124.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.5;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA053057: AB_2682028" "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favorable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.1;heart muscle: 26.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 152.2;Microglial cells: 450.9;Oligodendrocytes: 199.4" "Cancer enhanced" "Detected in many" "glioma: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.3;Sarcoma: 6.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 51: Oligodendrocytes - Unknown function" 14 Vesicles "HPA044271: AB_2732515, HPA059267: AB_2683961" "unprognostic (9.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.17e-1)" "unprognostic (9.56e-2)" "unprognostic (5.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.94e-2)" "unprognostic (7.75e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.16e-6)" "unprognostic (1.40e-3)" SYNDIG1L "capucin, DSPC1, IFITMD4, TMEM90A" ENSG00000183379 "Synapse differentiation inducing 1 like" A6NDD5 14 74405894-74426210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 44 "brain: 471.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.6;Bipolar cells: 6.6;Horizontal cells: 11.3;Inhibitory neurons: 4.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.1" "Region enriched" "Detected in all" 5 "basal ganglia: 991.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2" "Region enriched" "Detected in all" 8 "basal ganglia: 280.8" "Region enriched" "Detected in many" 7 "basal ganglia: 164.1" "HPA042594, HPA048487" Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 25: Bipolar cells - Visual perception" "HPA042594: AB_2678069, HPA048487: AB_2680416" "unprognostic (5.75e-2)" "unprognostic (9.96e-3)" "unprognostic (2.25e-2)" "unprognostic (5.51e-2)" "unprognostic (3.08e-3)" "unprognostic (5.72e-2)" "unprognostic (5.83e-2)" "unprognostic (4.51e-2)" "unprognostic (2.83e-2)" "unprognostic (5.74e-2)" "unprognostic (8.85e-2)" "unprognostic (1.63e-1)" "unprognostic (3.85e-2)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121687-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 126.7;choroid plexus: 155.4" "Cell type enhanced" "Detected in many" "Astrocytes: 521.7;Bipolar cells: 347.5;Excitatory neurons: 478.2;Inhibitory neurons: 462.4;Microglial cells: 301.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 56.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 19: Eosinophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 55: Non-specific - Transcription" 3 "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" SYNE2 "DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2" ENSG00000054654 "Spectrin repeat containing nuclear envelope protein 2" Q8WXH0 14 63761899-64226433 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 191.2" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 529.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 187.6" "Immune cell enhanced" "Detected in many" "eosinophil: 73.9" "Group enriched" "Detected in many" 11 "granulocytes: 73.9;T-cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003435, HPA050204" Enhanced Approved "Nuclear membrane,Intermediate filaments" No Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "Nuclear membrane, Intermediate filaments" "HPA003435: AB_1080162, HPA050204: AB_2681051" "unprognostic (1.93e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-1)" "unprognostic (2.33e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-3)" "unprognostic (9.04e-2)" "unprognostic (2.58e-3)" "unprognostic (1.99e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "prognostic favorable (3.56e-9)" "unprognostic (5.05e-3)" "unprognostic (3.14e-1)" "unprognostic (1.51e-2)" "unprognostic (4.80e-2)" SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95516650 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Rod photoreceptor cells: 117.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 14.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 66: Photoreceptor cells - Visual perception" "Nuclear membrane" "HPA055227: AB_2682747, HPA077140: AB_2686826" "unprognostic (4.63e-2)" "unprognostic (6.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.48e-3)" "unprognostic (7.15e-2)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.87e-1)" "unprognostic (8.50e-2)" "unprognostic (3.32e-1)" "unprognostic (7.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.19e-2)" SYNE4 "C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4" ENSG00000181392 "Spectrin repeat containing nuclear envelope family member 4" Q8N205 19 36003307-36008813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 34.1;Breast myoepithelial cells: 37.2;Cholangiocytes: 34.3;Cytotrophoblasts: 34.7;Syncytiotrophoblasts: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 22.6;prostate cancer: 30.1" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Region enriched" "Detected in single" 15 "cerebellum: 6.8" "Not detected" "Not detected" HPA060253 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 43 "HPA060253: AB_2684233" "unprognostic (8.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.24e-1)" "unprognostic (5.54e-2)" "unprognostic (2.42e-3)" "unprognostic (3.76e-2)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (3.36e-3)" "unprognostic (6.02e-2)" "prognostic favorable (8.64e-9)" "unprognostic (1.25e-1)" "unprognostic (2.54e-2)" "unprognostic (4.50e-1)" "unprognostic (1.97e-2)" SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 230.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 175.2;Melanocytes: 175.2" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.8;monocytes: 39.0;T-cells: 30.9" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 1: Erythroid cells - Oxygen transport" 1 Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 383.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" SYNGR3 ENSG00000127561 "Synaptogyrin 3" O43761 16 1989660-1994275 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 101.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 23.3;Horizontal cells: 17.0;Inhibitory neurons: 32.3;Oocytes: 47.1;Sertoli cells: 10.9;Spermatogonia: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034278, HPA042842" Enhanced Approved "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 69: Neurons - Neuronal signaling" 15 "Plasma membrane" "CAB034278: AB_2200905, HPA042842: AB_2678198" "unprognostic (8.89e-3)" "prognostic favorable (6.92e-4)" "unprognostic (6.07e-3)" "unprognostic (2.94e-3)" "unprognostic (2.92e-2)" "unprognostic (8.06e-3)" "unprognostic (2.52e-1)" "unprognostic (5.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.06e-1)" "unprognostic (3.69e-3)" "unprognostic (1.05e-1)" "prognostic favorable (7.12e-7)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.79e-1)" "unprognostic (8.78e-2)" SYNGR4 ENSG00000105467 "Synaptogyrin 4" O95473 19 48364367-48376377 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 52.9" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 153.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030075, HPA059286" Enhanced Approved "Golgi apparatus" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA030075: AB_10610559, HPA059286: AB_2683965" "unprognostic (1.58e-2)" "unprognostic (3.44e-2)" "unprognostic (3.18e-2)" "unprognostic (9.49e-4)" "unprognostic (2.51e-2)" "unprognostic (7.10e-2)" "unprognostic (2.52e-3)" "unprognostic (3.72e-3)" "unprognostic (2.87e-2)" "unprognostic (6.19e-2)" "unprognostic (6.69e-2)" "unprognostic (2.41e-2)" "unprognostic (2.02e-7)" "unprognostic (1.06e-2)" "unprognostic (1.74e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 22 Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" SYNPR "MGC26651, SPO" ENSG00000163630 Synaptoporin Q8TBG9 3 63228315-63616924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 257.0" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 611.4" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 9.0;lymphoma: 2.4" "Region enhanced" "Detected in all" "olfactory bulb: 743.7" "Low region specificity" "Detected in all" "HPA051368, HPA061671" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 69: Neurons - Neuronal signaling" 7 Vesicles "Nucleoplasm, Cytosol" "HPA051368: AB_2681456, HPA061671: AB_2684582" "unprognostic (1.69e-1)" "unprognostic (3.77e-2)" "unprognostic (3.14e-3)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.50e-1)" "unprognostic (5.32e-2)" "unprognostic (1.82e-1)" "unprognostic (1.89e-1)" SYP MRX96 ENSG00000102003 Synaptophysin P08247 X 49187815-49200218 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 427.0;retina: 301.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 471.7;Cone photoreceptor cells: 462.2;Horizontal cells: 235.4;Rod photoreceptor cells: 588.2" "Group enriched" "Detected in many" 6 "glioma: 12.8;pancreatic cancer: 5.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 55.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000076, HPA002858, CAB055505, CAB078999, HPA079659" Enhanced Supported NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" 29 "CAB000076: AB_2315411, CAB055505: AB_564017, CAB078999: , HPA002858: AB_1080153, HPA079659: " "unprognostic (2.08e-1)" "unprognostic (8.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.37e-3)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.87e-1)" "unprognostic (6.46e-5)" "unprognostic (8.52e-3)" "unprognostic (1.62e-1)" "unprognostic (3.44e-3)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.94e-1)" SYPL1 SYPL ENSG00000008282 "Synaptophysin like 1" Q16563 7 106090505-106112589 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 706.2;Spermatocytes: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014141 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 51: Thyroid gland - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 8 "HPA014141: AB_1857716" "unprognostic (8.88e-2)" "unprognostic (8.10e-2)" "unprognostic (3.39e-3)" "unprognostic (1.47e-1)" "unprognostic (4.76e-2)" "unprognostic (4.61e-2)" "unprognostic (8.74e-2)" "unprognostic (9.15e-2)" "unprognostic (3.71e-2)" "unprognostic (2.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic favorable (1.25e-9)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-1)" SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 350.6;tongue: 168.4" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 52.7" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.8;Sarcoma: 3.1" "Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" SYS1 "C20orf169, dJ453C12.4" ENSG00000204070 "SYS1 golgi trafficking protein" Q8N2H4 20 45361937-45376798 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046716 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 58: Macrophages - Innate immune response" 14 "HPA046716: AB_2679769" "unprognostic (8.24e-2)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.51e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.10e-2)" "unprognostic (1.63e-2)" "unprognostic (4.77e-1)" "unprognostic (4.66e-3)" "unprognostic (2.33e-1)" "unprognostic (4.28e-2)" "unprognostic (4.90e-2)" "unprognostic (4.38e-2)" "unprognostic (5.38e-3)" "unprognostic (2.01e-2)" SYT1 "P65, SVP65, SYT" ENSG00000067715 "Synaptotagmin 1" P21579 12 78863993-79452008 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 289.8;retina: 196.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 1057.9;Cone photoreceptor cells: 1116.3;Excitatory neurons: 3625.4;Horizontal cells: 791.9;Inhibitory neurons: 2790.0;Rod photoreceptor cells: 852.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.9;naive B-cell: 2.8" "Lineage enriched" "Detected in single" 4 "B-cells: 2.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 53.5" "Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008394, HPA064788" Enhanced Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 15 "HPA008394: AB_1857696, HPA064788: AB_2685351" "unprognostic (1.02e-3)" "unprognostic (2.55e-1)" "unprognostic (4.21e-3)" "unprognostic (3.77e-2)" "unprognostic (3.16e-2)" "unprognostic (3.68e-5)" "unprognostic (2.78e-2)" "unprognostic (1.83e-2)" "unprognostic (7.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (6.14e-3)" "unprognostic (3.05e-8)" "unprognostic (2.89e-2)" "unprognostic (8.26e-2)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" SYT10 ENSG00000110975 "Synaptotagmin 10" Q6XYQ8 12 33374238-33439819 "Predicted membrane proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "fallopian tube: 2.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.6;Ciliated cells: 7.7;Distal tubular cells: 12.3;Granulosa cells: 19.4;Horizontal cells: 10.7;Inhibitory neurons: 14.7;Late spermatids: 15.7;Schwann cells: 35.3" "Cancer enriched" "Detected in single" 5 "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Region enhanced" "Detected in all" "olfactory bulb: 49.5" "Low region specificity" "Detected in all" HPA055426 Approved Nucleoplasm,Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" "Nucleoplasm, Vesicles" "HPA055426: AB_2682812" "unprognostic (3.60e-1)" "unprognostic (4.93e-2)" "unprognostic (9.34e-4)" "unprognostic (5.53e-2)" "unprognostic (3.67e-1)" "unprognostic (4.74e-3)" "unprognostic (3.19e-1)" "unprognostic (1.97e-6)" "unprognostic (4.00e-1)" "unprognostic (2.39e-1)" "unprognostic (2.41e-1)" "unprognostic (1.91e-1)" SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.8;testis: 3.2;thyroid gland: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 201.6;Inhibitory neurons: 204.9;Oligodendrocyte precursor cells: 143.4;Oligodendrocytes: 183.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" SYT15 CHR10SYT ENSG00000204176 "Synaptotagmin 15" "Q9BQS2, X6R8R1" 10 46578217-46594173 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Alveolar cells type 1: 9.8;Alveolar cells type 2: 4.7;Endothelial cells: 5.2;Suprabasal keratinocytes: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "HPA036971, HPA036972, HPA064559" Uncertain Approved "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "HPA036971: AB_2675406, HPA036972: AB_2675407, HPA064559: AB_2685286" "unprognostic (1.64e-2)" "unprognostic (9.28e-3)" "unprognostic (1.54e-1)" "unprognostic (6.91e-4)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.02e-2)" "unprognostic (1.49e-2)" "unprognostic (3.19e-4)" "unprognostic (4.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-2)" "unprognostic (1.15e-3)" SYT15B ENSG00000277758 "Synaptotagmin 15B" X6R8R1 10 47744717-47763592 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in many" "lung: 10.6" "Cell type enhanced" "Detected in some" "Adipocytes: 2.4;Alveolar cells type 1: 10.8;Alveolar cells type 2: 6.4;Endothelial cells: 4.2;Lymphatic endothelial cells: 7.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA036971, HPA036972, HPA064559" Approved Approved "Golgi apparatus" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "HPA036971: AB_2675406, HPA036972: AB_2675407, HPA064559: AB_2685286" "unprognostic (2.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.15e-2)" "unprognostic (5.70e-2)" "unprognostic (4.59e-1)" "unprognostic (2.51e-1)" "unprognostic (2.06e-2)" "unprognostic (1.80e-1)" "unprognostic (3.17e-2)" "unprognostic (2.69e-2)" "unprognostic (1.97e-1)" "unprognostic (3.49e-5)" "unprognostic (4.52e-2)" "unprognostic (5.13e-2)" "unprognostic (6.35e-2)" "unprognostic (1.11e-2)" SYT16 "CHR14SYT, Strep14, SYT14L, yt14r" ENSG00000139973 "Synaptotagmin 16" Q17RD7 14 61811974-62112550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.6;testis: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 57.2;Excitatory neurons: 272.1;Inhibitory neurons: 267.6;Late spermatids: 41.5;Oligodendrocyte precursor cells: 119.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004199, HPA076871" Enhanced Approved Cytosol NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Neurons - Neuronal signaling" 20 Cytosol "HPA004199: AB_1080156, HPA076871: AB_2732324" "unprognostic (2.55e-2)" "unprognostic (1.43e-2)" "unprognostic (4.12e-1)" "unprognostic (8.88e-4)" "unprognostic (1.41e-1)" "unprognostic (9.08e-2)" "unprognostic (9.57e-2)" "unprognostic (9.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (3.41e-2)" "unprognostic (1.61e-2)" "unprognostic (3.06e-2)" "unprognostic (1.53e-3)" "unprognostic (2.15e-1)" SYT2 ENSG00000143858 "Synaptotagmin 2" Q8N9I0 1 202590596-202710454 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Differentiation "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 41.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 22.5;Horizontal cells: 27.7;Inhibitory neurons: 21.8;Oocytes: 88.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 8.4" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063655 Enhanced Supported NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" 24 "HPA063655: AB_2685077" "unprognostic (1.32e-2)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (2.24e-2)" "unprognostic (3.00e-1)" "unprognostic (2.35e-3)" "unprognostic (8.81e-3)" "unprognostic (1.17e-1)" "unprognostic (1.53e-2)" "unprognostic (6.33e-2)" "unprognostic (1.56e-2)" "unprognostic (6.23e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (5.17e-3)" SYT5 ENSG00000129990 "Synaptotagmin 5" O00445 19 55171196-55180289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 111.0;pituitary gland: 57.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 22.2;Excitatory neurons: 19.6;Inhibitory neurons: 11.4;Late spermatids: 45.1;Pancreatic endocrine cells: 11.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 28.7;Rhabdoid: 34.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078390 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA078390: AB_2732382" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (9.76e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (9.85e-2)" "unprognostic (3.24e-3)" "unprognostic (5.94e-2)" "unprognostic (1.36e-3)" "unprognostic (1.82e-1)" "prognostic favorable (5.54e-4)" "unprognostic (1.15e-3)" "unprognostic (3.71e-7)" "unprognostic (7.09e-2)" "unprognostic (5.21e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-1)" SYT6 ENSG00000134207 "Synaptotagmin 6" Q5T7P8 1 114089291-114153880 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 9.2;pancreas: 3.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 5.7;Horizontal cells: 25.8;Late spermatids: 14.7;Microglial cells: 25.9;Oligodendrocyte precursor cells: 7.1" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Group enriched" "Detected in all" 7 "basal ganglia: 31.3;olfactory bulb: 71.3" "Low region specificity" "Detected in many" HPA058362 Approved Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA058362: " "unprognostic (7.12e-2)" "unprognostic (2.03e-2)" "unprognostic (3.26e-3)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (3.60e-3)" "unprognostic (1.19e-1)" "unprognostic (4.71e-1)" "unprognostic (5.50e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.6;liver: 84.6;salivary gland: 55.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.3;Enteroendocrine cells: 49.0;Excitatory neurons: 79.4;Hepatocytes: 60.1;Horizontal cells: 76.8;Intestinal goblet cells: 44.0;Prostatic glandular cells: 105.3;Syncytiotrophoblasts: 76.8" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 40: Prostatic glandular cells - Transcription" 1 "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.4;skin 1: 63.4;urinary bladder: 39.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 125.9;Basal squamous epithelial cells: 300.7;Breast myoepithelial cells: 256.7;Cholangiocytes: 192.7;Ciliated cells: 97.8;Extravillous trophoblasts: 241.1;Squamous epithelial cells: 112.2" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 15.3;pancreatic cancer: 8.2" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: B-cells - B-cell function" 8 Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" TAAR1 "TA1, TAR1, TRAR1" ENSG00000146399 "Trace amine associated receptor 1" Q96RJ0 6 132643312-132659182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "stomach 1: 4.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 2.1" "Not detected" "Not detected" HPA055614 Approved NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" "HPA055614: AB_2682862" "unprognostic (2.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (2.68e-2)" TAAR5 PNR ENSG00000135569 "Trace amine associated receptor 5" O14804 6 132588592-132589741 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051703 Uncertain NA NA "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA051703: AB_2681580" TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 79.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Group enriched" "Detected in some" 4 "Brain cancer: 2.9;ovarian cancer: 1.2" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 2 "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 176.9" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.9;Leydig cells: 2.4;Ovarian stromal cells: 2.8;Serous glandular cells: 2.4;Sertoli cells: 2.7;Smooth muscle cells: 2.2" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" TACR3 "NK3R, NKR, TAC3R" ENSG00000169836 "Tachykinin receptor 3" P29371 4 103586031-103719985 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 1.3;retina: 2.6;urinary bladder: 1.8" "Group enriched" "Detected in some" 8 "Bipolar cells: 11.5;Excitatory neurons: 6.5;Extravillous trophoblasts: 5.4;Oligodendrocytes: 9.8;Oocytes: 6.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Sarcoma: 2.9" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009418 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA009418: AB_1857727" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (3.21e-1)" "unprognostic (5.52e-1)" "unprognostic (3.80e-1)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 961.9;salivary gland: 454.7;skin 1: 425.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1666.8;Basal respiratory cells: 2850.6;Basal squamous epithelial cells: 1785.3;Club cells: 1989.2;Ductal cells: 1987.3;Ionocytes: 2021.5;Squamous epithelial cells: 2760.9;Suprabasal keratinocytes: 2420.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "choroid plexus: 3.9;white matter: 1.1" "Immune cell enhanced" "Detected in some" "eosinophil: 15.1" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.1;monocytes: 4.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 603.0;head and neck cancer: 792.6" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" TAF1B "RAF1B, RAFI63, SL1, TAFI63" ENSG00000115750 "TATA-box binding protein associated factor, RNA polymerase I subunit B" Q53T94 2 9843443-9934416 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071254 Supported Nucleoplasm,Nucleoli NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 16: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Neurons - Neuronal signaling" 4 Nucleoli Nucleoplasm "HPA071254: " "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (8.58e-5)" "unprognostic (1.44e-3)" "unprognostic (5.43e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.94e-7)" "unprognostic (9.17e-2)" "unprognostic (3.29e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (2.98e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.59e-1)" "unprognostic (2.49e-1)" "unprognostic (2.79e-2)" "unprognostic (1.49e-2)" TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Ribosome" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 7 Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: AB_2682974, HPA060385: AB_2684271" "unprognostic (9.91e-3)" "unprognostic (4.38e-2)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "unprognostic (5.40e-3)" "unprognostic (6.46e-2)" "unprognostic (3.68e-3)" "unprognostic (9.70e-2)" "unprognostic (5.24e-3)" "unprognostic (3.55e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (3.17e-7)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (2.34e-1)" "unprognostic (6.37e-2)" TAFAZZIN "BTHS, CMD3A, EFE, EFE2, G4.5, TAZ, TAZ1" ENSG00000102125 "Tafazzin, phospholipid-lysophospholipid transacylase" Q16635 X 154411524-154421726 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Acyltransferase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039557 Approved Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" "Plasma membrane" "HPA039557: AB_10672899" "unprognostic (1.14e-1)" "prognostic favorable (5.70e-4)" "unprognostic (4.94e-3)" "unprognostic (1.43e-1)" "unprognostic (8.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.56e-2)" "unprognostic (8.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (4.68e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (4.00e-3)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" TANGO6 "FLJ12688, KIAA1746, TMCO7" ENSG00000103047 "Transport and golgi organization 6 homolog" Q9C0B7 16 68843531-69085182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 22.3;Early spermatids: 69.5;Excitatory neurons: 43.8;Inhibitory neurons: 55.0;Late spermatids: 81.2;Microglial cells: 24.2;Oligodendrocyte precursor cells: 36.3;Oligodendrocytes: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041312 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 21: Early spermatids - Spermatogenesis" "Golgi apparatus" Cytosol "HPA041312: AB_10796342" "unprognostic (8.55e-2)" "unprognostic (6.64e-2)" "unprognostic (4.66e-2)" "unprognostic (1.94e-2)" "unprognostic (3.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.50e-1)" "unprognostic (1.86e-1)" "unprognostic (2.22e-1)" "unprognostic (9.82e-3)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.20e-4)" "unprognostic (1.55e-2)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (6.02e-2)" TAOK2 "hKFC-C, KIAA0881, MAP3K17, PSK, PSK-1, PSK1, PSK1-BETA, TAO1, TAO2, Tao2beta" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skin - Keratinocyte (other), Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 17 "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: AB_2686513" "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" TAP2 "ABCB3, D6S217E, PSF2, RING11" ENSG00000204267 "Transporter 2, ATP binding cassette subfamily B member" Q03519 6 32821833-32838739 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001312 Approved Supported "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 2 "Endoplasmic reticulum" "Nuclear speckles" "HPA001312: AB_1080206" "unprognostic (2.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.90e-1)" "prognostic unfavorable (5.22e-8)" "unprognostic (5.32e-1)" "unprognostic (4.17e-2)" "unprognostic (2.35e-1)" "unprognostic (4.71e-2)" TAPBP TAPA ENSG00000231925 "TAP binding protein" O15533 6 33299694-33314284 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007066, CAB080405" Approved Approved "Nucleoli,Plasma membrane,Mitochondria" NA NA 20000 "Cluster 32: Basophils - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoli, Plasma membrane" Mitochondria "CAB080405: , HPA007066: AB_1857769" "prognostic favorable (2.76e-4)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.98e-2)" "unprognostic (1.59e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "prognostic favorable (6.29e-4)" "unprognostic (1.67e-2)" "unprognostic (2.37e-1)" "unprognostic (3.63e-1)" "unprognostic (1.61e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-1)" "unprognostic (6.54e-3)" TAPBPL "FLJ10143, TAPBP-R, TAPBPR" ENSG00000139192 "TAP binding protein like" Q9BX59 12 6451690-6466517 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 84.1;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039545 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 77: Plasma cells - Protein processing" 8 "HPA039545: AB_10673360" "prognostic favorable (1.98e-4)" "unprognostic (3.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (4.61e-2)" "unprognostic (1.91e-1)" "unprognostic (7.64e-2)" "unprognostic (4.07e-2)" "unprognostic (3.18e-1)" "unprognostic (5.66e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.04e-5)" "unprognostic (3.53e-2)" "unprognostic (7.61e-2)" "unprognostic (6.28e-2)" "prognostic favorable (7.86e-4)" TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.1;Late spermatids: 176.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Photoreceptor cells - Visual perception" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" TARM1 ENSG00000248385 "T cell-interacting, activating receptor on myeloid cells 1" B6A8C7 19 54069895-54081365 "Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "bone marrow: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051022, HPA054401" Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 66: Photoreceptor cells - Visual perception" "HPA051022: AB_2681315, HPA054401: AB_2682476" "unprognostic (1.56e-1)" TAS1R1 "GPR70, T1R1, TR1" ENSG00000173662 "Taste 1 receptor member 1" Q7RTX1 1 6555307-6579755 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 4.2" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Late spermatids: 17.2;Schwann cells: 4.0;Spermatogonia: 2.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034579, HPA034580" Approved NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 63: Late spermatids - Spermatogenesis" "HPA034579: AB_2674232, HPA034580: AB_10671504" "unprognostic (2.03e-2)" "unprognostic (9.29e-3)" "unprognostic (5.60e-4)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (4.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.53e-4)" "unprognostic (3.89e-2)" "unprognostic (3.15e-1)" "unprognostic (3.26e-2)" "unprognostic (3.17e-1)" "unprognostic (5.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.26e-2)" "unprognostic (8.28e-2)" "unprognostic (6.22e-2)" TAS1R3 T1R3 ENSG00000169962 "Taste 1 receptor member 3" Q7RTX0 1 1331280-1335314 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 11.9;lymphoid tissue: 3.6;salivary gland: 7.7" "Cell type enhanced" "Detected in some" "B-cells: 1.7;Plasma cells: 7.0;Serous glandular cells: 3.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 17 "B-cells: 1.6" "Cancer enhanced" "Detected in some" "Myeloma: 7.0" "Breast - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053439 Uncertain Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Golgi apparatus" "HPA053439: AB_2682150" "unprognostic (1.35e-2)" "unprognostic (1.45e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-3)" "unprognostic (4.32e-2)" "unprognostic (2.05e-1)" "unprognostic (6.95e-2)" "unprognostic (4.22e-1)" "unprognostic (8.44e-3)" "unprognostic (7.59e-3)" "unprognostic (8.37e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-1)" TAS2R1 "T2R1, TRB7" ENSG00000169777 "Taste 2 receptor member 1" Q9NYW7 5 9627347-9712378 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 7.3" "Group enriched" "Detected in some" 20 "Early spermatids: 26.2;Late spermatids: 75.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA051879 Uncertain NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" "HPA051879: AB_2681649" "unprognostic (2.19e-1)" TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825219-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Astrocytes: 5.9;Excitatory neurons: 13.9;Inhibitory neurons: 13.8;Microglial cells: 4.5;Oligodendrocyte precursor cells: 13.2;Oligodendrocytes: 10.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 4 "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" TAS2R38 "PTC, T2R61" ENSG00000257138 "Taste 2 receptor member 38" P59533 7 141972631-141973773 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0;lung cancer: 1.1" "Not detected" "Not detected" "HPA043862, HPA054366" Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA043862: AB_2678703, HPA054366: AB_2682464" "unprognostic (5.18e-3)" "unprognostic (6.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.58e-1)" "unprognostic (1.25e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-2)" "unprognostic (8.05e-2)" TAS2R39 ENSG00000236398 "Taste 2 receptor member 39" P59534 7 143183419-143184435 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA060680 Uncertain NA NA "Cluster 30: White matter - Myelination" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA060680: AB_2684341" TAS2R41 T2R59 ENSG00000221855 "Taste 2 receptor member 41" P59536 7 143477873-143478796 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057063 Uncertain NA NA "Cluster 16: Intestinal goblet cells - Mucin production" 1 "HPA057063: AB_2683324" TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" TAS2R5 T2R5 ENSG00000127366 "Taste 2 receptor member 5" Q9NYW4 7 141790217-141791367 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053742 Approved "Nucleoplasm,Nucleoli,Cytoplasmic bodies" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 6 "Nucleoplasm, Nucleoli" "Cytoplasmic bodies" "HPA053742: " "unprognostic (5.48e-3)" "unprognostic (3.90e-3)" "unprognostic (6.07e-2)" "unprognostic (8.00e-3)" "unprognostic (7.56e-2)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.71e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.13e-5)" "unprognostic (1.13e-2)" "unprognostic (8.29e-7)" "unprognostic (1.29e-1)" "unprognostic (3.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" TAS2R60 T2R60 ENSG00000185899 "Taste 2 receptor member 60" P59551 7 143443453-143444409 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA030416 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA030416: AB_10603344" "unprognostic (1.78e-2)" "unprognostic (7.98e-2)" TATDN1 CDA11 ENSG00000147687 "TatD DNase domain containing 1" Q6P1N9 8 124488485-124539458 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023634, HPA053045" Uncertain Supported Nucleoplasm NA NA 660000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 64: Non-specific - Ribosome" Nucleoplasm "HPA023634: AB_1857779, HPA053045: AB_2682024" "unprognostic (2.19e-3)" "unprognostic (3.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.23e-2)" "unprognostic (1.54e-3)" "unprognostic (2.28e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (2.53e-4)" "unprognostic (2.50e-1)" "unprognostic (6.33e-3)" "unprognostic (3.44e-2)" "unprognostic (4.30e-2)" "unprognostic (2.24e-1)" "unprognostic (5.12e-2)" TAX1BP1 "CALCOCO3, TXBP151" ENSG00000106052 "Tax1 binding protein 1" Q86VP1 7 27739331-27844564 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Autophagy, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 958.0;Syncytiotrophoblasts: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024432 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 25: Bipolar cells - Visual perception" 58 Cytosol Nucleoplasm "HPA024432: AB_1857783" "unprognostic (1.38e-2)" "unprognostic (5.52e-2)" "unprognostic (3.55e-2)" "unprognostic (2.71e-2)" "unprognostic (2.55e-1)" "unprognostic (9.83e-3)" "unprognostic (1.81e-2)" "unprognostic (2.36e-1)" "unprognostic (4.59e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.69e-1)" "prognostic favorable (2.80e-6)" "unprognostic (1.76e-1)" "unprognostic (4.76e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-1)" TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 39.9;intestine: 24.9;lymphoid tissue: 57.2" "Cell type enhanced" "Detected in many" "B-cells: 108.7;monocytes: 38.2;NK-cells: 189.5;T-cells: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 34.8;lymphoma: 25.7" "Adipose subcutaneous - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 3 "Nuclear bodies" "HPA069743: AB_2686186" "prognostic favorable (3.83e-4)" "prognostic favorable (4.20e-4)" "unprognostic (9.23e-2)" "unprognostic (3.84e-2)" "unprognostic (1.28e-3)" "prognostic favorable (1.86e-5)" "unprognostic (6.22e-3)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (3.55e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (7.18e-2)" "unprognostic (3.81e-2)" TBC1D19 FLJ11082 ENSG00000109680 "TBC1 domain family member 19" Q8N5T2 4 26576437-26756223 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 63.5;Excitatory neurons: 103.0;Inhibitory neurons: 91.3;Oligodendrocyte precursor cells: 96.2;Oligodendrocytes: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039592 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 1 "Nucleoplasm, Nuclear membrane" "HPA039592: AB_10671043" "unprognostic (2.64e-2)" "unprognostic (2.71e-2)" "unprognostic (2.94e-1)" "unprognostic (8.65e-2)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" "unprognostic (2.86e-1)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.90e-1)" "unprognostic (3.29e-2)" "unprognostic (4.28e-2)" "prognostic favorable (1.21e-7)" "unprognostic (1.04e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (3.51e-1)" TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 142.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 79: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Late spermatids - Spermatogenesis" 4 "HPA043613: AB_10963930" "unprognostic (2.16e-3)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (2.97e-1)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" TBC1D23 FLJ11046 ENSG00000036054 "TBC1 domain family member 23" Q9NUY8 3 100260992-100325251 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038151, HPA038152" Approved Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 55: Non-specific - Transcription" 7 "Golgi apparatus" "HPA038151: AB_10672405, HPA038152: AB_10672620" "unprognostic (9.23e-3)" "unprognostic (6.01e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (1.79e-2)" "unprognostic (6.18e-2)" "unprognostic (7.87e-3)" "unprognostic (6.16e-2)" "unprognostic (7.92e-2)" "unprognostic (2.02e-2)" "unprognostic (2.98e-3)" "unprognostic (3.66e-3)" "unprognostic (1.14e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (5.64e-2)" "unprognostic (2.32e-1)" TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 41.2;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cell Junctions" "HPA044712: AB_10795619, HPA068080: AB_2685948" "prognostic unfavorable (3.22e-4)" "unprognostic (5.23e-2)" "unprognostic (4.02e-2)" "unprognostic (6.41e-2)" "unprognostic (3.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-2)" "unprognostic (1.28e-1)" "unprognostic (4.66e-3)" "unprognostic (2.02e-2)" "unprognostic (8.19e-2)" "unprognostic (7.78e-3)" "unprognostic (1.61e-1)" TBC1D2B KIAA1055 ENSG00000167202 "TBC1 domain family member 2B" Q9UPU7 15 77984036-78077724 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 69.0;Mesothelial cells: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041833, HPA048174, HPA052663" Approved Enhanced Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Cytosol "HPA041833: AB_2732494, HPA048174: AB_2680297, HPA052663: AB_2681906" "unprognostic (3.13e-1)" "unprognostic (2.16e-1)" "unprognostic (8.25e-2)" "unprognostic (1.28e-2)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.07e-3)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (8.22e-3)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.23e-3)" "unprognostic (6.68e-2)" "unprognostic (3.07e-2)" "unprognostic (3.37e-1)" "unprognostic (3.19e-2)" TBC1D3 "DKFZp434P2235, PRC17, TBC1D3A" ENSG00000274611 "TBC1 domain family member 3" Q8IZP1 17 38181659-38192555 "Predicted membrane proteins" "GTPase activation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 11.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 29.9;Inhibitory neurons: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" TBC1D32 "bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235" ENSG00000146350 "TBC1 domain family member 32" Q96NH3 6 121079494-121334745 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.2" "Cell type enhanced" "Detected in many" "Astrocytes: 64.7;Excitatory neurons: 119.8;Inhibitory neurons: 83.6;Oligodendrocyte precursor cells: 99.0;Oligodendrocytes: 95.4;Rod photoreceptor cells: 111.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013413 Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 1 Mitochondria "HPA013413: AB_10602702" "unprognostic (3.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.12e-3)" "unprognostic (4.82e-2)" "unprognostic (2.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.60e-4)" "unprognostic (7.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (8.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.73e-2)" "unprognostic (1.57e-2)" "unprognostic (7.62e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" TBC1D3B "PRC17, TBC1D3I" ENSG00000274808 "TBC1 domain family member 3B" A6NDS4 17 36165683-36176636 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "Early spermatids: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.94e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (2.51e-1)" "unprognostic (1.17e-1)" "unprognostic (7.15e-2)" "unprognostic (9.96e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.34e-1)" TBC1D3C MGC44903 ENSG00000278299 "TBC1 domain family member 3C" Q6IPX1 17 38057693-38068634 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D3D ENSG00000274419 "TBC1 domain family member 3D" A0A087WVF3 17 38003976-38014908 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Cone photoreceptor cells: 1.7;Exocrine glandular cells: 1.3;Kupffer cells: 1.4;Rod photoreceptor cells: 2.0;Syncytiotrophoblasts: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D3E ENSG00000278599 "TBC1 domain family member 3E" A0A087X179 17 38127951-38138868 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.2" "Group enriched" "Detected in some" 40 "Astrocytes: 1.9;Excitatory neurons: 6.2;Inhibitory neurons: 5.8;Microglial cells: 1.8;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.18e-1)" "unprognostic (3.35e-1)" "unprognostic (3.51e-1)" "unprognostic (4.22e-2)" "unprognostic (6.28e-2)" "unprognostic (1.87e-2)" "unprognostic (5.07e-3)" "unprognostic (1.32e-3)" TBC1D3F ENSG00000275954 "TBC1 domain family member 3F" 17 36428618-36439566 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA046969 Uncertain Vesicles NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" Vesicles "HPA046969: " TBC1D3G ENSG00000260287 "TBC1 domain family member 3G" Q6DHY5 17 36323884-36334759 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Supported Approved Vesicles NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" 8 Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (4.41e-1)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" TBC1D3H ENSG00000274226 "TBC1 domain family member 3H" P0C7X1 17 36377531-36388435 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Approved Vesicles NA NA "Cluster 78: Testis - Transcription" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D3I ENSG00000274933 "TBC1 domain family member 3I" A0A087WXS9 17 36253456-36264570 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "testis: 6.8" "Group enriched" "Detected in some" 114 "Early spermatids: 33.3;Late spermatids: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D3K ENSG00000273513 "TBC1 domain family member 3K" A0A087X1G2 17 37924415-37935371 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 15: Kidney cancer - Membrane components" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TBC1D3L ENSG00000274512 "TBC1 domain family member 3L" B9A6J9 17 37978155-37989060 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Early spermatids: 8.8;Gastric mucus-secreting cells: 5.9;Schwann cells: 5.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (5.14e-2)" "unprognostic (8.71e-2)" "unprognostic (8.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (6.34e-2)" "unprognostic (3.19e-1)" "unprognostic (9.50e-2)" "unprognostic (1.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.80e-2)" "unprognostic (6.63e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (1.28e-3)" TBC1D5 KIAA0210 ENSG00000131374 "TBC1 domain family member 5" Q92609 3 17157162-18444817 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 214.9;Excitatory neurons: 321.9;Inhibitory neurons: 336.3;Microglial cells: 309.5;Oligodendrocyte precursor cells: 320.7;Oligodendrocytes: 526.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035125, HPA035126" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 51: Oligodendrocytes - Unknown function" 10 Vesicles "Golgi apparatus" "HPA035125: AB_2674479, HPA035126: AB_10670696" "unprognostic (1.87e-1)" "unprognostic (3.57e-1)" "unprognostic (2.86e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (4.30e-3)" "unprognostic (3.07e-2)" "unprognostic (3.31e-1)" "unprognostic (3.56e-2)" "unprognostic (6.27e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (1.75e-7)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (5.72e-2)" "unprognostic (7.07e-2)" TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 66.4" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 204.0" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 1: Erythroid cells - Oxygen transport" 22 "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.5;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.3" "Lineage enriched" "Detected in many" 5 "monocytes: 38.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" TBCD ENSG00000141556 "Tubulin folding cofactor D" Q9BTW9 17 82752042-82945914 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, GTPase activation" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 137.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045200 Approved NA NA 6200 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 18: Non-specific - Ribosome" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 80: Non-specific - Transcription" 1 "HPA045200: AB_10969134" "unprognostic (4.15e-1)" "unprognostic (1.01e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-3)" "unprognostic (2.72e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.39e-5)" "unprognostic (3.41e-3)" "unprognostic (9.03e-3)" "unprognostic (5.35e-2)" "unprognostic (1.75e-3)" "unprognostic (6.40e-2)" "unprognostic (1.16e-1)" "unprognostic (4.96e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 10.4;Endothelial cells: 8.6;Fibroblasts: 4.8;Lymphatic endothelial cells: 13.2;Schwann cells: 7.3;Smooth muscle cells: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.2" "Group enriched" "Detected in many" 5 "granulocytes: 69.0;Hofbauer cells: 108.6;Kupffer cells: 199.3;Macrophages: 132.4;Microglial cells: 182.5;monocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 291.7;classical monocyte: 291.1;eosinophil: 315.0;intermediate monocyte: 436.4;myeloid DC: 113.8;neutrophil: 258.5;non-classical monocyte: 404.5" "Group enriched" "Detected in all" 23 "dendritic cells: 113.8;granulocytes: 315.0;monocytes: 436.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 14.7;Leukemia: 15.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" TCEANC2 "C1orf83, FLJ32112" ENSG00000116205 "Transcription elongation factor A N-terminal and central domain containing 2" Q96MN5 1 54053584-54112519 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.7;Spermatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046918 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 3 Nucleoplasm Vesicles "HPA046918: AB_2679864" "unprognostic (2.80e-1)" "unprognostic (6.19e-2)" "unprognostic (6.56e-3)" "unprognostic (2.34e-1)" "unprognostic (5.12e-3)" "unprognostic (1.35e-3)" "unprognostic (1.73e-5)" "unprognostic (8.64e-2)" "unprognostic (7.93e-3)" "unprognostic (6.59e-2)" "unprognostic (3.55e-1)" "unprognostic (3.52e-2)" "unprognostic (9.63e-2)" "unprognostic (2.26e-3)" "unprognostic (8.57e-2)" "unprognostic (7.51e-3)" "unprognostic (2.08e-1)" TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 280.9" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 113.2;Hofbauer cells: 115.3;Macrophages: 115.3;monocytes: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 2 Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" TCTA ENSG00000145022 "T cell leukemia translocation altered" P57738 3 49412212-49416476 "Disease related genes, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007342 Approved Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 80: Non-specific - Transcription" 4 Cytosol "HPA007342: AB_2202399" "unprognostic (5.58e-2)" "unprognostic (4.33e-2)" "unprognostic (6.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.17e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "prognostic favorable (6.76e-4)" "unprognostic (3.74e-1)" "unprognostic (3.38e-3)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.00e-15)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (3.43e-1)" "unprognostic (6.41e-3)" TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 38.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 26.1;Cone photoreceptor cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Uncertain "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 8 "Golgi apparatus" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" Other NA NA 4400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Dendritic cells - Antigen presentation" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" TDRKH TDRD2 ENSG00000182134 "Tudor and KH domain containing" Q9Y2W6 1 151770107-151791416 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 29.1;testis: 21.5" "Group enriched" "Detected in many" 5 "Early spermatids: 19.9;Late spermatids: 61.8;Oocytes: 58.8;Spermatocytes: 44.5;Spermatogonia: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016419, HPA019625" Approved Approved Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Brain - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 36: Late spermatids - Unknown function" 4 Cytosol Centrosome "HPA016419: AB_1857870, HPA019625: AB_1857871" "unprognostic (2.27e-3)" "unprognostic (2.89e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (2.63e-1)" "unprognostic (2.91e-1)" "unprognostic (2.06e-1)" "unprognostic (3.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-2)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-3)" "unprognostic (1.14e-1)" TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 955.8;Suprabasal keratinocytes: 669.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 59: Suprabasal keratinocytes - Cornification" 22 "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" TECTA "DFNA12, DFNA8, DFNB21" ENSG00000109927 "Tectorin alpha" O75443 11 121101243-121191490 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Early spermatids: 3.8;Excitatory neurons: 9.5;Inhibitory neurons: 6.9;Late spermatids: 3.6;Oligodendrocyte precursor cells: 4.7;Oocytes: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Sarcoma: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018870 Approved "Secreted in other tissues" Other NA NA "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 34: Neurons - Neuronal signaling" "HPA018870: AB_1857879" "unprognostic (1.12e-3)" "unprognostic (2.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.45e-2)" "unprognostic (4.30e-2)" "unprognostic (3.11e-1)" "unprognostic (3.00e-2)" "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.39e-6)" "unprognostic (1.22e-1)" "unprognostic (4.15e-3)" "unprognostic (6.97e-3)" "unprognostic (1.12e-1)" "unprognostic (3.28e-2)" "unprognostic (4.19e-2)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.7" "Group enriched" "Detected in some" 6 "Adipocytes: 67.0;Endothelial cells: 74.2;Lymphatic endothelial cells: 34.9;Microglial cells: 36.7;Oligodendrocyte precursor cells: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 17.5;testis cancer: 16.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 7750000 13000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 6 "Nuclear bodies, Cytosol" "HPA041348: AB_10794514, HPA041473: AB_10795593" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (2.94e-2)" "unprognostic (5.99e-3)" "unprognostic (1.47e-3)" "unprognostic (2.21e-1)" "unprognostic (6.75e-2)" "unprognostic (3.15e-3)" TENM1 "ODZ1, ODZ3, TEN-M1, TEN1, TNM" ENSG00000009694 "Teneurin transmembrane protein 1" Q9UKZ4 X 124375903-125204312 "Predicted membrane proteins, Transporters" "Stress response, Transcription, Transcription regulation" "Neuropeptide, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.5" "Group enriched" "Detected in many" 5 "Excitatory neurons: 121.5;Inhibitory neurons: 444.9;Oligodendrocyte precursor cells: 408.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 41.4" "Heart muscle - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002848, HPA063910" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Plasma membrane" "HPA002848: AB_1079523, HPA063910: " "unprognostic (1.71e-3)" "unprognostic (8.25e-2)" "unprognostic (3.14e-1)" "unprognostic (8.68e-4)" "unprognostic (5.76e-3)" "unprognostic (3.51e-2)" "unprognostic (7.07e-2)" "unprognostic (2.68e-4)" "unprognostic (6.58e-2)" "unprognostic (1.71e-1)" "unprognostic (4.49e-3)" "unprognostic (3.58e-1)" "unprognostic (2.71e-2)" "unprognostic (4.41e-2)" "unprognostic (1.99e-1)" "unprognostic (3.25e-3)" "unprognostic (4.44e-2)" TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 166979029-168264157 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 33.9" "Cell type enhanced" "Detected in many" "Astrocytes: 486.4;Cardiomyocytes: 187.2;Excitatory neurons: 683.5;Inhibitory neurons: 927.0" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 25.6;Brain cancer: 25.6" "Kidney - Podocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 11000 "Cluster 30: Heart muscle - Heart development" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" Nucleoli "HPA038018: , HPA038420: AB_10674682, HPA068691: AB_2686019" "unprognostic (6.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (9.16e-3)" "unprognostic (3.88e-3)" "unprognostic (3.81e-3)" "unprognostic (5.81e-2)" "unprognostic (2.41e-1)" "unprognostic (4.62e-2)" "unprognostic (2.10e-2)" "unprognostic (3.68e-3)" "unprognostic (4.34e-2)" "unprognostic (4.69e-5)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (5.16e-4)" "prognostic unfavorable (7.52e-4)" TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 12.7" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 610.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" TENM4 "DOC4, KIAA1302, ODZ4, Ten-M4, TEN4" ENSG00000149256 "Teneurin transmembrane protein 4" Q6N022 11 78652829-79441030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 15.2;parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Astrocytes: 127.6;Early spermatids: 104.2;Excitatory neurons: 326.0;Inhibitory neurons: 285.5;Microglial cells: 111.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 36.0" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019521, HPA065961" Approved NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 22: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 7 "HPA019521: AB_2670171, HPA065961: AB_2685588" "unprognostic (2.81e-1)" "unprognostic (9.25e-2)" "unprognostic (1.64e-1)" "unprognostic (2.96e-3)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-2)" "unprognostic (1.24e-1)" "unprognostic (3.01e-1)" "unprognostic (3.79e-1)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "unprognostic (6.51e-3)" "unprognostic (5.40e-3)" "unprognostic (5.64e-2)" "unprognostic (7.07e-2)" "unprognostic (9.81e-3)" TENT4A "LAK-1, PAPD7, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Terminal nucleotidyltransferase 4A" Q5XG87 5 6713432-6757044 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 40: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 29: Non-specific - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favorable (8.55e-4)" TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Plasma cells: 3.0;Spermatocytes: 1.9;Spermatogonia: 3.1;Undifferentiated cells: 1.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 61: Plasma cells - Immunoglobulins & histones" 9 Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" TEX10 "bA208F1.2, FLJ20287, Ipi1" ENSG00000136891 "Testis expressed 10" Q9NXF1 9 100302077-100352942 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.1;Syncytiotrophoblasts: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045434 Approved Nucleoplasm,Mitochondria NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 Nucleoplasm Mitochondria "HPA045434: AB_10965650" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" "unprognostic (1.21e-1)" "unprognostic (8.28e-2)" "unprognostic (5.26e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (2.43e-2)" "unprognostic (3.74e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (3.25e-2)" "unprognostic (2.07e-1)" "unprognostic (7.39e-2)" "unprognostic (3.27e-1)" "unprognostic (2.66e-3)" "unprognostic (9.63e-3)" TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "testis: 114.4" "Cell type enriched" "Detected in some" 11 "Spermatocytes: 950.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 45.4" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA020648: AB_1857908, HPA057116: AB_2683341" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "prognostic favorable (3.90e-6)" "unprognostic (1.69e-2)" "unprognostic (3.84e-2)" "unprognostic (8.34e-2)" "unprognostic (6.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.53e-3)" "unprognostic (5.59e-3)" TEX261 "MGC32043, TEG-261" ENSG00000144043 "Testis expressed 261" Q6UWH6 2 70968325-70994873 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016631 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 66: Photoreceptor cells - Visual perception" Nucleoplasm Cytosol "HPA016631: AB_2240434" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (4.23e-4)" "unprognostic (5.52e-3)" "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (3.15e-2)" "unprognostic (3.70e-3)" "unprognostic (3.36e-1)" "unprognostic (5.59e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.99e-1)" TEX38 "ATPAF1-AS1, C1orf223, LOC374973, THEG4" ENSG00000186118 "Testis expressed 38" Q6PEX7 1 46668855-46673594 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 414 "testis: 377.8" "Group enriched" "Detected in some" 67 "Early spermatids: 2396.4;Late spermatids: 5111.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA073711 Approved Vesicles NA NA "Cluster 10: Testis - Spermatid development" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Late spermatids - Unknown function" Vesicles "HPA073711: " "unprognostic (8.46e-2)" "unprognostic (1.99e-1)" "unprognostic (3.14e-2)" "unprognostic (8.86e-2)" "unprognostic (6.81e-3)" "unprognostic (3.50e-1)" "unprognostic (1.99e-1)" "unprognostic (9.21e-2)" "unprognostic (5.39e-2)" "unprognostic (4.15e-3)" "unprognostic (4.93e-4)" "unprognostic (2.64e-1)" "unprognostic (5.28e-2)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (7.84e-2)" "unprognostic (3.48e-1)" TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 45 Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" TFR2 "HFE3, TFRC2" ENSG00000106327 "Transferrin receptor 2" Q9UP52 7 100620416-100642779 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 337.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 343.4" "Cancer enriched" "Detected in many" 70 "liver cancer: 136.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 23 "basophil: 2.5;eosinophil: 1.9" "Lineage enriched" "Detected in single" 26 "granulocytes: 2.5" "Cancer enriched" "Detected in some" 7 "Leukemia: 23.6" "Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016255, HPA017171, HPA073125" Enhanced Approved "Golgi apparatus" NA NA 410000 "Cluster 46: Basophils - Proteolysis" "Cluster 83: Liver - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Hepatocytes - Metabolism" 2 "Golgi apparatus" "CAB016255: AB_628395, HPA017171: , HPA073125: " "unprognostic (4.18e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" "unprognostic (4.13e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.29e-2)" "unprognostic (4.49e-2)" "unprognostic (9.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.90e-1)" "unprognostic (1.18e-9)" "unprognostic (6.51e-2)" "unprognostic (1.68e-1)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196012511-196082153 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 451.2;monocytes: 612.3;Syncytiotrophoblasts: 467.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" Receptor NA NA 1310000000 38000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Non-specific - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" 23 "Endosomes, Lysosomes" "CAB000153: AB_2533029, HPA028598: AB_10601599" "unprognostic (2.95e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" "unprognostic (6.75e-2)" "unprognostic (7.88e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.92e-2)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.34e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-3)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.62e-2)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.7" "Cell type enhanced" "Detected in many" "Ductal cells: 31.3;Early spermatids: 30.9;Oligodendrocyte precursor cells: 55.7;Oligodendrocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 143.6;Early spermatids: 120.9;Late spermatids: 121.3;Microglial cells: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 123.2" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 28: Dendritic cells - Antigen presentation" 3 "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 389.3;Endothelial cells: 383.4;Fibroblasts: 209.7;Lymphatic endothelial cells: 308.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" "Secreted to blood" Receptor NA NA 810000 "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 54 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 143.4;Endothelial cells: 124.4;Fibroblasts: 171.7;Leydig cells: 144.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 35.3;MAIT T-cell: 19.5;memory CD4 T-cell: 8.9;memory CD8 T-cell: 19.2;naive CD8 T-cell: 12.8;NK-cell: 16.7" "Group enriched" "Detected in many" 18 "NK-cells: 16.7;T-cells: 35.3" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 73.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" Receptor NA NA 50000000 "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" TGFBR3L GEMP ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "pituitary gland: 103.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.8;Granulosa cells: 20.3;Plasma cells: 10.2;Proximal tubular cells: 7.6;Sertoli cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" TGIF2-RAB5IF TGIF2-C20orf24 ENSG00000259399 "TGIF2-RAB5IF readthrough" 20 36574553-36612384 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA076106 Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 73: B-cells - B-cell function" Mitochondria "HPA076106: " "unprognostic (7.38e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (5.58e-2)" "unprognostic (2.62e-2)" "unprognostic (1.94e-1)" "unprognostic (7.39e-2)" "unprognostic (2.22e-2)" "unprognostic (6.57e-3)" "unprognostic (3.97e-2)" "unprognostic (2.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" TGOLN2 "TGN38, TGN46, TGN48, TGN51, TTGN2" ENSG00000152291 "Trans-golgi network protein 2" O43493 2 85318027-85328251 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011489, HPA012609, HPA012723" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA 12000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 58: Macrophages - Innate immune response" 3 "Golgi apparatus" Nucleoplasm "CAB011489: AB_443302, HPA012609: AB_1857976, HPA012723: AB_1857975" "unprognostic (3.03e-2)" "unprognostic (1.82e-2)" "unprognostic (2.35e-1)" "unprognostic (4.39e-2)" "unprognostic (3.90e-2)" "unprognostic (2.66e-1)" "unprognostic (5.50e-3)" "unprognostic (2.49e-1)" "unprognostic (2.98e-1)" "unprognostic (1.52e-2)" "unprognostic (5.19e-2)" "unprognostic (2.72e-2)" "unprognostic (6.30e-2)" "unprognostic (2.83e-2)" "unprognostic (3.22e-2)" "unprognostic (2.04e-2)" "unprognostic (5.37e-2)" THAP12 "DAP4, P52rIPK, PRKRIR, THAP0" ENSG00000137492 "THAP domain containing 12" O43422 11 76349898-76381132 "Plasma proteins, Predicted membrane proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008758, HPA077077" Approved Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 4 Cytosol "HPA008758: AB_1855714, HPA077077: " "unprognostic (2.79e-1)" "unprognostic (9.79e-2)" "unprognostic (1.16e-3)" "unprognostic (6.47e-2)" "unprognostic (8.85e-3)" "unprognostic (1.23e-1)" "unprognostic (4.03e-3)" "unprognostic (1.08e-1)" "unprognostic (6.68e-3)" "unprognostic (1.48e-1)" "unprognostic (1.57e-2)" "unprognostic (2.65e-2)" "unprognostic (7.98e-2)" "unprognostic (2.06e-1)" "unprognostic (3.95e-2)" "unprognostic (1.54e-1)" "unprognostic (4.79e-2)" THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044982 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 28 "Nucleoplasm, Cytosol" "HPA044982: AB_10959786" "unprognostic (3.17e-2)" "unprognostic (1.70e-2)" "unprognostic (6.56e-2)" "unprognostic (1.36e-2)" "unprognostic (8.35e-2)" "unprognostic (7.23e-2)" "unprognostic (1.16e-3)" "unprognostic (3.61e-2)" "unprognostic (7.56e-2)" "unprognostic (2.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.21e-1)" "prognostic favorable (1.46e-4)" "unprognostic (2.57e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.07e-1)" THBD "BDCA-3, CD141, THRM" ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 252.8;Endothelial cells: 251.1;Lymphatic endothelial cells: 205.8;Macrophages: 163.4;Peritubular cells: 254.5;Schwann cells: 206.1;Skeletal myocytes: 143.4;Squamous epithelial cells: 241.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.9;granulocytes: 24.6;monocytes: 9.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 97.2" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 5550000 1300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 19 "Nucleoplasm, Cytosol" "CAB002425: AB_563497, HPA002982: AB_1078444" "unprognostic (1.96e-1)" "unprognostic (2.93e-3)" "unprognostic (8.70e-2)" "unprognostic (3.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (7.81e-3)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (7.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.58e-3)" "unprognostic (9.71e-2)" THOC1 "HPR1, P84" ENSG00000079134 "THO complex subunit 1" Q96FV9 18 214520-268050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019096, HPA019687" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Testis - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 15 "Nuclear speckles" "HPA019096: AB_1857979, HPA019687: AB_1857980" "prognostic favorable (8.43e-4)" "unprognostic (2.06e-3)" "unprognostic (1.84e-1)" "unprognostic (3.69e-2)" "unprognostic (8.75e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (6.74e-3)" "unprognostic (2.49e-3)" "prognostic favorable (2.89e-5)" "unprognostic (3.60e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (2.03e-1)" "unprognostic (2.24e-1)" "unprognostic (3.42e-1)" "prognostic favorable (9.62e-4)" THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 18.2;Astrocytes: 24.2;Basal respiratory cells: 13.3;Endothelial cells: 23.5;Lymphatic endothelial cells: 20.6;Microglial cells: 17.0;Spermatocytes: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796, HPA071106" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" No No 1400000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Cytosol "CAB020796: , HPA012611: AB_1857990, HPA071106: " "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.3" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Bipolar cells: 160.4;Horizontal cells: 97.6;Inhibitory neurons: 470.6;Microglial cells: 101.1;Oligodendrocyte precursor cells: 246.2" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 53 "basophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 11.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" "Developmental protein" NA NA 6100000 "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 12 "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" THSD7B KIAA1679 ENSG00000144229 "Thrombospondin type 1 domain containing 7B" Q9C0I4 2 136765545-137677718 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 18.8" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 146.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4;Rhabdoid: 2.7" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051416, HPA056745" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" 23 Nucleoplasm Cytosol "HPA051416: AB_2681477, HPA056745: AB_2683224" "unprognostic (4.65e-3)" "unprognostic (2.25e-1)" "unprognostic (8.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.80e-3)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.20e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-6)" "unprognostic (2.42e-3)" "unprognostic (1.89e-1)" "unprognostic (4.31e-2)" "unprognostic (4.30e-2)" THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 276.2;smooth muscle: 292.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 146.7;Excitatory neurons: 112.0;Fibroblasts: 177.7;Horizontal cells: 114.6;Inhibitory neurons: 99.7;Leydig cells: 97.9;Muller glia cells: 96.9;Proximal tubular cells: 161.2;Smooth muscle cells: 128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 459.1;thyroid cancer: 259.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 53.9;testis: 140.0" "Group enriched" "Detected in some" 36 "Early spermatids: 1158.2;Late spermatids: 1972.3" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.5;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 4 "Kidney cancer: 9.0;lymphoma: 4.2;Myeloma: 10.3" "Adipose subcutaneous - Macrophages, Liver - Kupffer cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 32000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 307.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 77: Plasma cells - Protein processing" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 230.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 18 Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" TIMM21 "C18orf55, HSPC154, TIM21" ENSG00000075336 "Translocase of inner mitochondrial membrane 21" Q9BVV7 18 74148523-74160531 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010587, HPA051543" Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "HPA010587: AB_1851244, HPA051543: AB_2681528" "unprognostic (4.88e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "unprognostic (8.61e-2)" "unprognostic (3.81e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (9.22e-5)" "unprognostic (1.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.93e-2)" "unprognostic (4.79e-3)" "unprognostic (1.55e-3)" "prognostic favorable (1.38e-9)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.66e-2)" TIMM22 "TEX4, TIM22" ENSG00000177370 "Translocase of inner mitochondrial membrane 22" Q9Y584 17 997129-1003671 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 40 "basophil: 4.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.0" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045138 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 3 "HPA045138: AB_10962055" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (2.57e-1)" "unprognostic (8.69e-3)" "unprognostic (3.00e-2)" "unprognostic (2.75e-2)" "unprognostic (2.16e-2)" "unprognostic (9.36e-2)" "unprognostic (2.37e-1)" "unprognostic (1.80e-1)" "prognostic favorable (3.42e-4)" "unprognostic (1.27e-1)" "prognostic favorable (1.41e-4)" "unprognostic (2.45e-1)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.70e-3)" TIMM23 TIM23 ENSG00000265354 "Translocase of inner mitochondrial membrane 23" O14925 10 45972489-46003742 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 107.2;Early spermatids: 122.0;Spermatocytes: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA031408 Approved Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 18 Mitochondria "HPA031408: AB_10600828" "unprognostic (4.09e-2)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (1.15e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "prognostic favorable (6.79e-4)" "unprognostic (4.41e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-1)" "unprognostic (7.78e-2)" "unprognostic (5.54e-2)" "unprognostic (7.20e-2)" "unprognostic (2.21e-1)" TIMM50 "TIM50, TIM50L" ENSG00000105197 "Translocase of inner mitochondrial membrane 50" Q3ZCQ8 19 39480412-39493785 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" RNA-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 165.7;Late spermatids: 649.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048843, HPA056448" Enhanced Supported Nucleoplasm,Mitochondria NA NA 12000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 3 "Nucleoplasm, Mitochondria" "HPA048843: , HPA056448: AB_2683137" "unprognostic (1.49e-1)" "unprognostic (6.97e-2)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" "unprognostic (4.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.11e-2)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (3.11e-2)" "unprognostic (9.43e-2)" "unprognostic (2.01e-2)" "unprognostic (4.14e-3)" "unprognostic (3.04e-2)" "unprognostic (9.87e-2)" "unprognostic (3.82e-2)" "unprognostic (4.04e-2)" TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" 53 Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" TLCD1 ENSG00000160606 "TLC domain containing 1" Q96CP7 17 28724348-28727935 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.6;Extravillous trophoblasts: 38.9;Syncytiotrophoblasts: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in many" 11 "dendritic cells: 21.9" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042366 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 80: Non-specific - Endocytosis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Hepatocytes - Metabolism" 7 "HPA042366: AB_10794419" "unprognostic (1.23e-1)" "unprognostic (3.78e-2)" "unprognostic (8.52e-2)" "unprognostic (3.74e-2)" "unprognostic (1.42e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.47e-3)" "unprognostic (9.96e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.05e-5)" "unprognostic (1.56e-1)" "unprognostic (7.56e-2)" "unprognostic (1.86e-2)" "unprognostic (3.93e-2)" TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 76.5;Distal enterocytes: 85.6;Proximal enterocytes: 64.8;Skeletal myocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 18.7" HPA046063 Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 126.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.0;Erythroid cells: 176.4;Hepatocytes: 233.1" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 83: Liver - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Erythroid cells - Oxygen transport" 61 "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" TLCD5 "MGC17839, TMEM136" ENSG00000181264 "TLC domain containing 5" Q6ZRR5 11 120325296-120333686 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 50.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 88.4;Rod photoreceptor cells: 87.4;Sertoli cells: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.2" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074432 Approved Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Photoreceptor cells - Visual perception" Vesicles Cytosol "HPA074432: AB_2686689" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.65e-2)" "unprognostic (3.31e-2)" "unprognostic (6.81e-3)" "unprognostic (1.22e-1)" "unprognostic (1.39e-2)" "unprognostic (2.58e-1)" "unprognostic (2.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.71e-2)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (7.28e-2)" TLR10 CD290 ENSG00000174123 "Toll like receptor 10" Q9BXR5 4 38772238-38782990 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 46.6" "Cell type enhanced" "Detected in some" "B-cells: 58.6;dendritic cells: 13.0;Macrophages: 6.5;Microglial cells: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 39.1;naive B-cell: 24.1" "Lineage enriched" "Detected in many" 5 "B-cells: 39.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 27.2" "Adipose visceral - Neutrophils, Prostate - T-cells" "Low region specificity" "Detected in many" HPA001940 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 4 "Plasma membrane" "Endoplasmic reticulum" "HPA001940: " "unprognostic (5.41e-5)" "unprognostic (2.41e-4)" "unprognostic (1.91e-3)" "unprognostic (8.22e-4)" "unprognostic (6.48e-2)" "unprognostic (9.98e-4)" "unprognostic (9.31e-2)" "unprognostic (8.76e-3)" "unprognostic (4.08e-3)" "unprognostic (7.26e-2)" "unprognostic (8.76e-2)" "unprognostic (6.90e-2)" "unprognostic (2.98e-3)" "unprognostic (3.90e-1)" "unprognostic (1.81e-2)" "unprognostic (3.14e-3)" "unprognostic (1.88e-2)" TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.1;lymphoid tissue: 50.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 106.9;Macrophages: 117.2;monocytes: 342.1;Mucus glandular cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 200.3;intermediate monocyte: 179.4;myeloid DC: 121.5;neutrophil: 460.9;non-classical monocyte: 122.1" "Group enriched" "Detected in all" 48 "dendritic cells: 121.5;granulocytes: 460.9;monocytes: 200.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.0;Leukemia: 10.6" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 6 "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" TLR3 CD283 ENSG00000164342 "Toll like receptor 3" O15455 4 186068911-186088073 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Receptor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 76.2;Schwann cells: 36.0" "Cancer enriched" "Detected in many" 4 "renal cancer: 10.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.9;memory CD8 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 12.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025658 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" 4 "CAB025658: " "unprognostic (2.13e-2)" "unprognostic (2.15e-1)" "unprognostic (7.26e-2)" "unprognostic (7.47e-3)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-2)" "unprognostic (9.28e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (1.17e-1)" "unprognostic (4.72e-3)" "unprognostic (1.18e-1)" "unprognostic (4.52e-3)" "unprognostic (3.89e-2)" "unprognostic (1.83e-1)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Hofbauer cells: 72.9;Kupffer cells: 156.6;Macrophages: 80.4;monocytes: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.9" "Cancer enhanced" "Detected in many" "Brain cancer: 11.7" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004025, HPA049174" Approved Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 10 "Golgi apparatus, Plasma membrane" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 48.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.4;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.4;monocytes: 30.8" "Low cancer specificity" "Detected in some" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38822897-38856817 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.8" "Cell type enhanced" "Detected in some" "B-cells: 14.2;Hofbauer cells: 8.5;Kupffer cells: 7.6;Macrophages: 14.9;Microglial cells: 19.7;Mucus glandular cells: 6.6;Serous glandular cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 11.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 2 "Endoplasmic reticulum" "HPA062733: AB_2684853" "unprognostic (9.82e-2)" "unprognostic (4.76e-2)" "unprognostic (3.30e-2)" "unprognostic (3.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.45e-2)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (7.62e-7)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (7.78e-2)" "unprognostic (2.12e-2)" TLR7 ENSG00000196664 "Toll like receptor 7" Q9NYK1 X 12867072-12890361 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 6.2" "Cell type enhanced" "Detected in some" "B-cells: 9.5;dendritic cells: 37.2;Hofbauer cells: 23.3;Langerhans cells: 8.5;Macrophages: 23.2;Microglial cells: 13.4;monocytes: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 20.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "Leukemia: 1.5;lymphoma: 6.1;Myeloma: 5.5" "Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059613 Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" "HPA059613: AB_2684083" "unprognostic (1.22e-1)" "unprognostic (1.09e-2)" "unprognostic (2.36e-3)" "unprognostic (9.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.06e-2)" "unprognostic (8.27e-2)" "unprognostic (6.20e-3)" "unprognostic (3.75e-1)" "unprognostic (6.91e-2)" "unprognostic (3.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (4.17e-3)" "unprognostic (1.19e-3)" "unprognostic (1.53e-3)" "unprognostic (1.34e-1)" TLR8 "CD288, hTLR8" ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 10.3;lymphoid tissue: 16.3" "Group enriched" "Detected in some" 4 "Kupffer cells: 47.8;Macrophages: 21.5;monocytes: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 73 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 77 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001608 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 Nucleoplasm Vesicles "HPA046058: AB_2679519, HPA055621: AB_2682865" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (1.68e-1)" "unprognostic (2.20e-2)" "unprognostic (5.79e-1)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA054064: AB_2682366" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.55e-3)" "unprognostic (1.15e-1)" "unprognostic (8.37e-2)" "unprognostic (2.29e-1)" "unprognostic (8.62e-2)" "unprognostic (2.51e-2)" "unprognostic (5.40e-2)" "unprognostic (4.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (2.92e-2)" "unprognostic (2.63e-1)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1132.0;Ductal cells: 1294.4;Endothelial cells: 1323.4;Exocrine glandular cells: 1166.2;Glandular and luminal cells: 1904.7;Lymphatic endothelial cells: 1081.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.0" "Group enriched" "Detected in many" 4 "Adipocytes: 205.7;Endothelial cells: 149.8;Lymphatic endothelial cells: 167.6" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 89.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "HPA058640, HPA069378" Approved Approved "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 30 "Plasma membrane" "HPA058640: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 258.9" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 833.9" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.0;Gastric cancer: 2.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 914.4;intestine: 632.2;liver: 682.2" "Cell type enriched" "Detected in some" 4 "Cholangiocytes: 2121.5" "Group enriched" "Detected in many" 10 "liver cancer: 249.4;pancreatic cancer: 130.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 68.8;colorectal cancer: 35.5;Gastric cancer: 74.3;liver cancer: 79.3;pancreatic cancer: 37.8" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" 19 "Plasma membrane" Cytosol "HPA046430: AB_2679662" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.83e-1)" "unprognostic (4.66e-2)" "unprognostic (1.91e-2)" "unprognostic (4.97e-1)" TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 169.5;liver: 199.4" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 199.9;Hepatocytes: 237.5;Intestinal goblet cells: 192.6;Paneth cells: 251.0;Proximal enterocytes: 575.3" "Cancer enriched" "Detected in many" 9 "liver cancer: 219.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 16.0;Gastric cancer: 17.2;liver cancer: 34.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (4.44e-2)" "unprognostic (9.33e-2)" "unprognostic (3.57e-2)" "unprognostic (1.95e-1)" "unprognostic (5.21e-3)" TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 45.6" "Cell type enhanced" "Detected in many" "Adipocytes: 25.8;granulocytes: 28.6;Hofbauer cells: 53.3;Kupffer cells: 27.3;Langerhans cells: 60.9;Macrophages: 43.8;Microglial cells: 44.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 77.1;eosinophil: 196.3;neutrophil: 118.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 196.3" "Group enriched" "Detected in many" 5 "Leukemia: 10.5;lymphoma: 9.0;Myeloma: 3.5" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Macrophages, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" TM6SF2 Lpr4 ENSG00000213996 "Transmembrane 6 superfamily member 2" Q9BZW4 19 19264364-19273391 "Human disease related genes, Predicted membrane proteins, Transporters" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 73.4;liver: 32.8" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 229.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066026 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 8 "HPA066026: AB_2685598" "unprognostic (2.41e-1)" "unprognostic (4.81e-3)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (3.29e-1)" "unprognostic (2.35e-1)" "unprognostic (1.39e-3)" "unprognostic (4.00e-2)" "unprognostic (4.15e-2)" "unprognostic (4.53e-4)" "unprognostic (9.55e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (4.56e-2)" "unprognostic (1.51e-1)" "unprognostic (6.15e-2)" TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 238.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.0;Hepatocytes: 181.3;Muller glia cells: 171.4;Prostatic glandular cells: 143.4;Suprabasal keratinocytes: 205.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 109.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 2 "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 247.1" "Cell type enhanced" "Detected in all" "Late spermatids: 164.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" TM9SF1 "HMP70, MP70" ENSG00000100926 "Transmembrane 9 superfamily member 1" O15321 14 24189149-24195687 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059249 Supported Approved "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.27e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (9.31e-2)" "unprognostic (1.48e-1)" "unprognostic (3.84e-2)" "unprognostic (1.19e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.62e-3)" "unprognostic (2.44e-1)" "unprognostic (4.24e-1)" "unprognostic (2.20e-1)" "unprognostic (4.18e-3)" TM9SF2 P76 ENSG00000125304 "Transmembrane 9 superfamily member 2" Q99805 13 99446311-99564048 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005657 Supported NA NA 2100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 1 "HPA005657: AB_1080303" "unprognostic (9.77e-3)" "unprognostic (3.51e-2)" "unprognostic (2.85e-2)" "unprognostic (1.09e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.21e-7)" "unprognostic (6.49e-2)" "unprognostic (8.55e-2)" "unprognostic (2.20e-2)" "unprognostic (2.21e-1)" TM9SF3 SMBP ENSG00000077147 "Transmembrane 9 superfamily member 3" Q9HD45 10 96518110-96587452 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039609 Approved Approved "Golgi apparatus,Vesicles" NA NA 240000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Vesicles "Golgi apparatus" "HPA039609: AB_10673535" "unprognostic (3.33e-2)" "unprognostic (4.45e-2)" "unprognostic (1.43e-2)" "unprognostic (5.11e-2)" "unprognostic (4.95e-1)" "unprognostic (1.08e-2)" "unprognostic (1.16e-2)" "unprognostic (3.09e-2)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (4.14e-3)" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (8.28e-3)" "unprognostic (6.18e-2)" TM9SF4 "dJ836N17.2, KIAA0255" ENSG00000101337 "Transmembrane 9 superfamily member 4" Q92544 20 32109714-32167258 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064099 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 77: Plasma cells - Protein processing" 1 "HPA064099: AB_2685190" "unprognostic (3.10e-2)" "unprognostic (9.03e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.37e-6)" "unprognostic (3.85e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.37e-1)" "unprognostic (3.23e-3)" "unprognostic (1.91e-1)" "unprognostic (6.65e-2)" "unprognostic (7.68e-2)" "unprognostic (6.98e-3)" "unprognostic (7.66e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 7 Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" TMBIM4 "CGI-119, GAAP, LFG4, S1R, ZPRO" ENSG00000155957 "Transmembrane BAX inhibitor motif containing 4" Q9HC24 12 66135846-66170027 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077642 Supported "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 35: Respiratory epithelial cells - Unknown function" "Golgi apparatus" "HPA077642: AB_2686849" "unprognostic (5.41e-2)" "unprognostic (1.27e-1)" "unprognostic (3.19e-1)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (5.62e-2)" "unprognostic (7.18e-3)" "unprognostic (8.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.33e-2)" "unprognostic (3.36e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.68e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-3)" TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1748.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2131.1;Late spermatids: 2633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 55 "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" TMC3 ENSG00000188869 "Transmembrane channel like 3" Q7Z5M5 15 81331088-81374213 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 51 "parathyroid gland: 80.9" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.0" "Cancer enhanced" "Detected in single" "breast cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040265, HPA040510" Enhanced Supported Cytosol NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA040265: AB_10795379, HPA040510: AB_10796123" "unprognostic (1.17e-2)" "unprognostic (3.43e-1)" "unprognostic (3.14e-1)" "unprognostic (8.33e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (4.85e-3)" "unprognostic (2.20e-2)" "unprognostic (3.12e-2)" "unprognostic (1.77e-1)" "unprognostic (6.20e-5)" "unprognostic (2.32e-1)" "unprognostic (1.97e-7)" "unprognostic (1.60e-1)" "unprognostic (5.31e-2)" "unprognostic (1.26e-1)" "unprognostic (5.96e-2)" TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 44.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 114.5;Distal enterocytes: 144.1;Proximal enterocytes: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 51.9;stomach 1: 44.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 265.3;Exocrine glandular cells: 179.4;Gastric mucus-secreting cells: 181.6;Ionocytes: 356.7;Oocytes: 204.4;Proximal enterocytes: 351.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "choroid plexus: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.0;Gastric cancer: 35.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;lymphoid tissue: 74.3" "Cell type enhanced" "Detected in many" "monocytes: 140.1;NK-cells: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Kupffer cells, Skin - Outer root sheath cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 4 "HPA051430: AB_2681483" "unprognostic (6.34e-2)" "unprognostic (5.14e-2)" "unprognostic (5.55e-2)" "unprognostic (2.81e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" "unprognostic (5.36e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-1)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "prognostic favorable (3.20e-4)" TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;testis: 9.3;urinary bladder: 7.8" "Cell type enhanced" "Detected in many" "Early spermatids: 219.4;Late spermatids: 45.8;Oligodendrocytes: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Early spermatids - Unknown function" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 73.1;intestine: 49.7;lymphoid tissue: 109.3" "Cell type enhanced" "Detected in many" "B-cells: 51.3;granulocytes: 34.0;Hofbauer cells: 31.0;Langerhans cells: 43.1;monocytes: 42.7;NK-cells: 65.0;T-cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 53.0;lymphoma: 27.5;Myeloma: 52.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 7: T-cells - T-cell receptor" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" TMCC1 KIAA0779 ENSG00000172765 "Transmembrane and coiled-coil domain family 1" O94876 3 129647792-129893711 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 113.0;Excitatory neurons: 199.7;Inhibitory neurons: 193.1;Microglial cells: 121.7;Oligodendrocyte precursor cells: 169.8;Oligodendrocytes: 194.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 11.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.2" "Cancer enhanced" "Detected in all" "Kidney cancer: 65.9" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053894 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" "HPA053894: AB_2682295" "unprognostic (4.26e-2)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (2.60e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (7.75e-3)" "unprognostic (1.13e-1)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.77e-6)" "unprognostic (6.82e-3)" "unprognostic (2.90e-1)" "unprognostic (1.20e-1)" "unprognostic (2.32e-1)" TMCC2 "FLJ38497, HUCEP11" ENSG00000133069 "Transmembrane and coiled-coil domain family 2" O75069 1 205227946-205285632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 86.9;brain: 38.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.9;Cone photoreceptor cells: 25.5;Erythroid cells: 101.9;Horizontal cells: 32.1;Oligodendrocytes: 67.9;Rod photoreceptor cells: 35.6" "Cancer enhanced" "Detected in many" "melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Erythroid cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014254 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 1: Erythroid cells - Oxygen transport" 1 "HPA014254: AB_1851326" "unprognostic (2.59e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (2.61e-2)" "unprognostic (4.18e-1)" "unprognostic (5.59e-2)" "unprognostic (2.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.53e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-5)" "unprognostic (3.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-3)" "unprognostic (3.06e-2)" "unprognostic (4.01e-1)" "unprognostic (3.43e-3)" TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.2;Distal enterocytes: 67.5;Microglial cells: 67.1;monocytes: 72.4;Oligodendrocytes: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 47.0;neutrophil: 70.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 70.1" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Neutrophils - Degranulation" 1 "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 5: Enterocytes - Absorption" "Endoplasmic reticulum" "HPA054768: AB_2682597, HPA078775: " "unprognostic (1.22e-2)" "unprognostic (3.28e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (5.17e-7)" "prognostic unfavorable (3.21e-4)" "unprognostic (5.92e-2)" "unprognostic (4.16e-2)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.85e-1)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (9.80e-2)" TMCO3 "C13orf11, FLJ20623" ENSG00000150403 "Transmembrane and coiled-coil domains 3" Q6UWJ1 13 113491021-113554590 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 20.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039561, HPA048126" Uncertain Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Cytosol "HPA039561: AB_2676573, HPA048126: AB_2680276" "unprognostic (7.89e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (6.78e-2)" "unprognostic (7.88e-2)" "unprognostic (2.89e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (2.93e-2)" "unprognostic (9.44e-2)" "unprognostic (3.08e-3)" "unprognostic (2.76e-2)" "unprognostic (8.47e-3)" "unprognostic (3.70e-3)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (6.27e-3)" "prognostic unfavorable (4.10e-4)" TMCO4 DKFZp686C23231 ENSG00000162542 "Transmembrane and coiled-coil domains 4" Q5TGY1 1 19682240-19799945 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA014601, HPA014620" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Endoplasmic reticulum" "HPA014601: AB_2204302, HPA014620: AB_2669051" "unprognostic (3.31e-3)" "unprognostic (8.94e-2)" "unprognostic (9.71e-2)" "prognostic favorable (3.71e-4)" "unprognostic (6.99e-3)" "unprognostic (5.46e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (9.21e-2)" "unprognostic (2.60e-2)" "unprognostic (2.30e-1)" "unprognostic (1.84e-1)" "unprognostic (2.71e-2)" "prognostic favorable (4.12e-11)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" "unprognostic (9.81e-2)" "prognostic favorable (3.64e-4)" TMCO5A "MGC35118, TMCO5" ENSG00000166069 "Transmembrane and coiled-coil domains 5A" Q8N6Q1 15 37921939-37967724 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 162 "testis: 106.5" "Group enriched" "Detected in some" 131 "Early spermatids: 1026.4;Late spermatids: 3943.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA056530, HPA064017" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 18: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 5 "Plasma membrane, Cytosol" "HPA056530: AB_2683167, HPA064017: " "unprognostic (2.60e-1)" "unprognostic (1.69e-4)" TMED1 "Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L" ENSG00000099203 "Transmembrane p24 trafficking protein 1" Q13445 19 10832067-10836318 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018507 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 50: Connective tissue cells - ECM organization" 2 "HPA018507: AB_1858063" "unprognostic (6.98e-2)" "unprognostic (3.42e-1)" "unprognostic (3.03e-3)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (2.27e-1)" "unprognostic (1.98e-2)" "unprognostic (4.20e-2)" "unprognostic (9.86e-2)" "unprognostic (7.27e-2)" "unprognostic (9.52e-2)" "unprognostic (4.93e-2)" "prognostic favorable (8.66e-5)" "unprognostic (9.49e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-2)" "unprognostic (2.45e-2)" TMED10 "p23, P24(DELTA), p24d1, p24delta1, TMP21" ENSG00000170348 "Transmembrane p24 trafficking protein 10" P49755 14 75131469-75176612 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 704.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034442, CAB037251, HPA047139, HPA050539" Enhanced Supported "Golgi apparatus" NA NA 220000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 8 "Golgi apparatus" "CAB034442: AB_2204336, CAB037251: AB_1841216, HPA047139: AB_2679951, HPA050539: AB_2681163" "unprognostic (2.00e-1)" "unprognostic (1.73e-2)" "unprognostic (2.02e-1)" "unprognostic (2.51e-3)" "unprognostic (4.06e-1)" "unprognostic (1.17e-3)" "unprognostic (5.88e-2)" "unprognostic (1.21e-1)" "unprognostic (3.68e-2)" "unprognostic (6.46e-3)" "unprognostic (1.01e-2)" "unprognostic (1.27e-2)" "unprognostic (1.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (2.06e-2)" TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 728.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 7 Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 397.6" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 335.2;Serous glandular cells: 746.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 75: Serous glandular cells - Salivary secretion" "Golgi apparatus" "HPA049314: AB_2680708, HPA076949: AB_2686820" "prognostic unfavorable (7.71e-4)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (8.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.03e-3)" "unprognostic (2.42e-2)" "unprognostic (2.49e-1)" "unprognostic (4.85e-1)" "unprognostic (9.06e-2)" "unprognostic (8.09e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.16e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" TMED4 "HNLF, p24a3, p24alpha3" ENSG00000158604 "Transmembrane p24 trafficking protein 4" Q7Z7H5 7 44577894-44582287 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved "Intracellular and membrane" Transport NA NA 24000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "HPA014650: AB_1858066" "unprognostic (7.34e-2)" "unprognostic (1.68e-3)" "unprognostic (1.46e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.09e-3)" "unprognostic (4.50e-3)" "unprognostic (2.54e-2)" "unprognostic (3.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.42e-3)" "unprognostic (4.65e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.21e-1)" "unprognostic (6.12e-2)" "unprognostic (4.11e-1)" "unprognostic (6.61e-2)" TMED5 "CGI-100, p24g2, p24gamma2" ENSG00000117500 "Transmembrane p24 trafficking protein 5" Q9Y3A6 1 93149742-93180516 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050289 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Liver - Plasma proteins" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 58: Macrophages - Innate immune response" 2 "HPA050289: AB_2681074" "unprognostic (3.35e-1)" "unprognostic (1.44e-2)" "unprognostic (2.02e-3)" "unprognostic (4.38e-1)" "unprognostic (3.16e-1)" "unprognostic (4.86e-2)" "unprognostic (2.83e-3)" "unprognostic (6.37e-2)" "unprognostic (8.60e-2)" "unprognostic (3.72e-2)" "unprognostic (1.64e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (6.01e-2)" "unprognostic (1.86e-1)" "unprognostic (4.46e-2)" "unprognostic (1.38e-1)" TMED6 "MGC23911, p24g5, p24gamma5" ENSG00000157315 "Transmembrane p24 trafficking protein 6" Q8WW62 16 69343250-69351786 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 289.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 23.0;Distal enterocytes: 10.9;Enteroendocrine cells: 11.6;Exocrine glandular cells: 31.4;Gastric mucus-secreting cells: 11.2;Pancreatic endocrine cells: 17.0;Paneth cells: 10.1;Proximal tubular cells: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA012532 Approved NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA012532: AB_1858065" "unprognostic (6.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.31e-3)" "prognostic favorable (7.74e-5)" "unprognostic (9.84e-3)" "unprognostic (7.57e-2)" "unprognostic (2.40e-1)" "unprognostic (1.20e-1)" "unprognostic (7.94e-2)" "unprognostic (3.74e-1)" "unprognostic (2.94e-2)" "unprognostic (4.76e-2)" "unprognostic (4.58e-3)" "unprognostic (9.71e-2)" "unprognostic (1.50e-1)" "unprognostic (1.36e-1)" "unprognostic (4.52e-3)" TMED7 "CGI-109, FLJ90481, p24g3, p24gamma3" ENSG00000134970 "Transmembrane p24 trafficking protein 7" Q9Y3B3 5 115613210-115632992 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008960, CAB025883" Supported NA NA 13000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB025883: , HPA008960: AB_1080280" "unprognostic (1.40e-1)" "unprognostic (8.42e-2)" "unprognostic (1.45e-2)" "unprognostic (1.22e-1)" "unprognostic (2.04e-1)" "unprognostic (4.35e-2)" "unprognostic (1.27e-1)" "unprognostic (2.26e-3)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (6.15e-3)" "unprognostic (4.10e-2)" "unprognostic (6.82e-2)" "unprognostic (4.95e-2)" "unprognostic (3.06e-1)" "unprognostic (4.79e-2)" "unprognostic (1.22e-1)" TMED9 "HSGP25L2G, p24a2, p24alpha2" ENSG00000184840 "Transmembrane p24 trafficking protein 9" Q9BVK6 5 177592203-177597242 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1068.4;Syncytiotrophoblasts: 879.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved NA NA 36000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "HPA014650: AB_1858066" "unprognostic (5.75e-3)" "unprognostic (4.35e-2)" "unprognostic (1.37e-1)" "unprognostic (3.82e-2)" "unprognostic (9.37e-3)" "unprognostic (5.14e-3)" "unprognostic (2.55e-2)" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (7.00e-2)" "unprognostic (4.01e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.88e-5)" "unprognostic (2.88e-1)" "unprognostic (4.71e-2)" "unprognostic (9.07e-2)" "unprognostic (3.65e-2)" TMEFF1 "C9orf2, CT120.1, H7365" ENSG00000241697 "Transmembrane protein with EGF like and two follistatin like domains 1" Q8IYR6 9 100473149-100577636 "Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 12.7;testis: 3.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.7;Gastric mucus-secreting cells: 1.2;Schwann cells: 4.0" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 28.7" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051501 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 9: Endometrial stromal cells - Transcription" "HPA051501: AB_2681509" "unprognostic (1.96e-1)" "unprognostic (2.30e-1)" "unprognostic (9.69e-3)" "unprognostic (2.32e-2)" "unprognostic (9.02e-2)" "unprognostic (3.59e-2)" "unprognostic (2.87e-2)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (1.05e-1)" "unprognostic (5.04e-6)" "unprognostic (1.30e-4)" "unprognostic (1.52e-1)" "unprognostic (3.97e-2)" "unprognostic (3.44e-3)" TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 25.3;prostate: 35.4;seminal vesicle: 12.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 401.3;Inhibitory neurons: 364.3;Oligodendrocyte precursor cells: 197.6;Oligodendrocytes: 1244.6;Oocytes: 161.7" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 17.2;prostate cancer: 27.6" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 5 "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 186.6" "Cell type enhanced" "Detected in many" "Adipocytes: 49.7;Basal prostatic cells: 47.4;Endothelial cells: 46.4;Fibroblasts: 33.0;Leydig cells: 38.1;Lymphatic endothelial cells: 49.1;Peritubular cells: 55.0" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 49.8;Rhabdoid: 19.8" "Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 57: Lung - Lung function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 32 Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Glandular and luminal cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 11 "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" TMEM104 "FLJ00021, FLJ20255" ENSG00000109066 "Transmembrane protein 104" Q8NE00 17 74776499-74839753 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044330 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 57: Platelets - Hemostasis" Nucleoplasm "Golgi apparatus" "HPA044330: AB_10960543" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (5.95e-2)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (7.46e-2)" "unprognostic (2.86e-2)" "unprognostic (4.75e-1)" "prognostic favorable (1.97e-5)" "unprognostic (8.14e-2)" "unprognostic (6.17e-2)" "unprognostic (8.46e-2)" "unprognostic (7.95e-2)" "unprognostic (2.82e-3)" "unprognostic (1.00e-2)" TMEM106B "FLJ11273, MGC33727" ENSG00000106460 "Transmembrane protein 106B" Q9NUM4 7 12211270-12243367 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Amyotrophic lateral sclerosis, Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058342 Approved Supported Endosomes,Lysosomes NA NA "Cluster 27: T-cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 2 "Endosomes, Lysosomes" "HPA058342: AB_2683684" "unprognostic (5.29e-2)" "unprognostic (2.34e-2)" "unprognostic (4.20e-2)" "unprognostic (6.20e-2)" "unprognostic (2.73e-1)" "unprognostic (1.87e-2)" "unprognostic (3.50e-2)" "unprognostic (5.89e-2)" "unprognostic (4.44e-2)" "unprognostic (1.30e-1)" "unprognostic (3.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.75e-3)" "unprognostic (5.52e-2)" "unprognostic (3.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.70e-1)" TMEM106C MGC5576 ENSG00000134291 "Transmembrane protein 106C" Q9BVX2 12 47963569-47968878 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 219.5;Muller glia cells: 267.9;Proximal enterocytes: 388.4;Undifferentiated cells: 227.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047204 Enhanced NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 37 "HPA047204: AB_2679982" "unprognostic (1.63e-2)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.27e-8)" "unprognostic (1.05e-1)" "unprognostic (1.90e-2)" "unprognostic (1.52e-3)" "unprognostic (3.60e-1)" "unprognostic (7.29e-2)" "prognostic favorable (4.62e-4)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-2)" "unprognostic (1.83e-1)" TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 55.1" "Cell type enhanced" "Detected in all" "Ciliated cells: 122.6;Cone photoreceptor cells: 117.2;Plasma cells: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 32: Basophils - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 38 "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 33.8;skeletal muscle: 22.3" "Group enriched" "Detected in many" 4 "Astrocytes: 199.1;Excitatory neurons: 345.5;Inhibitory neurons: 456.7;Oligodendrocyte precursor cells: 450.4" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Neuroblastoma: 56.7" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 55000 "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 3 "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" TMEM109 MGC5508 ENSG00000110108 "Transmembrane protein 109" Q9BVC6 11 60914158-60923443 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011785 Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 13 "Nuclear membrane, Cytosol" "HPA011785: AB_1858075" "unprognostic (5.23e-2)" "unprognostic (9.02e-2)" "unprognostic (2.46e-2)" "unprognostic (2.69e-2)" "unprognostic (1.23e-1)" "unprognostic (2.40e-2)" "unprognostic (5.29e-3)" "unprognostic (2.95e-1)" "unprognostic (2.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.52e-1)" "unprognostic (3.63e-2)" "unprognostic (1.83e-1)" "unprognostic (2.82e-1)" "unprognostic (1.51e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (2.68e-4)" TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 78.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062854 Supported Supported Mitochondria No No "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 40 Mitochondria "HPA062854: AB_2684882" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (3.55e-1)" "unprognostic (3.36e-3)" "unprognostic (1.45e-2)" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.17e-2)" "unprognostic (4.61e-2)" TMEM115 PL6 ENSG00000126062 "Transmembrane protein 115" Q12893 3 50354750-50359521 "Plasma proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006319, HPA015497" Supported Supported "Golgi apparatus" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 50: Connective tissue cells - ECM organization" 11 "Golgi apparatus" "CAB006319: AB_425880, HPA015497: AB_1858076" "unprognostic (1.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.59e-2)" "unprognostic (1.65e-3)" "unprognostic (2.32e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.00e-2)" "unprognostic (6.00e-2)" "unprognostic (2.05e-2)" "unprognostic (1.75e-3)" "unprognostic (2.65e-2)" "prognostic favorable (1.04e-7)" "unprognostic (4.88e-3)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" TMEM116 FLJ90167 ENSG00000198270 "Transmembrane protein 116" Q8NCL8 12 111931282-112013185 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 58.0;parathyroid gland: 57.6" "Cell type enhanced" "Detected in many" "Early spermatids: 71.9;Spermatocytes: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "T-cells: 19.4" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040720 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Microtubules Nucleoplasm "HPA040720: AB_10795623" "unprognostic (8.91e-2)" "unprognostic (1.95e-3)" "unprognostic (1.18e-2)" "unprognostic (1.71e-1)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" "unprognostic (2.93e-2)" "unprognostic (6.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.34e-1)" "unprognostic (3.27e-3)" "unprognostic (9.12e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.41e-1)" "unprognostic (1.33e-1)" "unprognostic (2.85e-2)" "unprognostic (3.19e-3)" TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 62.2;Excitatory neurons: 212.9;Inhibitory neurons: 182.6;Microglial cells: 76.9;Oligodendrocyte precursor cells: 115.6;Oligodendrocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 8: Neurons - Neuronal signaling" "HPA046223: AB_10960636" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "unprognostic (4.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (2.89e-1)" "unprognostic (6.26e-2)" "unprognostic (1.99e-3)" "unprognostic (1.74e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (9.20e-3)" "unprognostic (3.80e-1)" TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 32.2;Late spermatids: 10.6;Microglial cells: 14.3;Peritubular cells: 24.7;Smooth muscle cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 26.1;Neuroblastoma: 33.5;thyroid cancer: 27.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" TMEM120B ENSG00000188735 "Transmembrane protein 120B" A0PK00 12 121712752-121783001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 96.1;NK-cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014066 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 19: NK-cells - Adaptive immune response" 46 "Nucleoli fibrillar center" Cytosol "HPA014066: AB_1845296" "unprognostic (8.80e-3)" "unprognostic (3.31e-2)" "unprognostic (1.95e-2)" "unprognostic (1.40e-2)" "unprognostic (3.10e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (3.62e-1)" "unprognostic (3.29e-1)" "unprognostic (5.54e-2)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (5.86e-2)" "unprognostic (8.02e-3)" "unprognostic (2.31e-1)" "unprognostic (2.13e-3)" "unprognostic (4.72e-2)" TMEM121 "hole, MGC4659, TMEM121A" ENSG00000184986 "Transmembrane protein 121" Q9BTD3 14 105526583-105530202 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049857 Uncertain Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Neuronal - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 12 Cytosol "HPA049857: AB_2680917" "unprognostic (4.25e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-3)" "unprognostic (2.20e-2)" "unprognostic (1.31e-1)" "unprognostic (9.50e-2)" "unprognostic (1.88e-3)" "unprognostic (9.54e-2)" "unprognostic (3.47e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-3)" "unprognostic (5.31e-2)" "unprognostic (5.48e-4)" "unprognostic (2.83e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (5.90e-2)" TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.7;prostate: 6.4" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 6.6;Hofbauer cells: 3.1;Late spermatids: 11.4;Oligodendrocyte precursor cells: 3.3;Prostatic glandular cells: 7.6" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.7;monocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.8;Neuroblastoma: 4.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Prostate - Prostate glandular cells, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 13: Spermatids - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Monocytes - Innate immune response" 6 "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 73.4;pancreas: 87.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.1;Alveolar cells type 2: 178.6;Distal enterocytes: 75.1;Proximal enterocytes: 169.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" TMEM126A "DKFZp586C1924, OPA7" ENSG00000171202 "Transmembrane protein 126A" Q9H061 11 85647967-85656547 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 201.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046648 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA046648: AB_2679737" "unprognostic (3.79e-2)" "unprognostic (4.75e-3)" "unprognostic (2.08e-3)" "unprognostic (1.08e-3)" "unprognostic (2.08e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.60e-5)" "unprognostic (8.25e-2)" "unprognostic (6.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.02e-2)" "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (6.94e-2)" "unprognostic (2.17e-1)" TMEM126B HT007 ENSG00000171204 "Transmembrane protein 126B" Q8IUX1 11 85628573-85636539 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014480, HPA019186" Uncertain Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA014480: AB_1858083, HPA019186: AB_1858084" "unprognostic (1.11e-1)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (5.67e-1)" "unprognostic (1.44e-1)" "unprognostic (5.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-2)" "unprognostic (6.70e-3)" "unprognostic (4.42e-2)" "unprognostic (4.30e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (5.86e-2)" "unprognostic (2.66e-2)" TMEM128 MGC13159 ENSG00000132406 "Transmembrane protein 128" Q5BJH2 4 4235542-4248223 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044809 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 6: Ovarian stromal cells - Transcription" 1 "HPA044809: AB_10963539" "unprognostic (4.97e-2)" "unprognostic (4.32e-2)" "unprognostic (3.23e-2)" "unprognostic (3.65e-1)" "unprognostic (2.39e-1)" "unprognostic (2.10e-1)" "unprognostic (2.94e-2)" "unprognostic (8.81e-2)" "unprognostic (1.09e-1)" "unprognostic (9.11e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.14e-3)" "unprognostic (1.72e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" TMEM130 "DKFZp761L1417, FLJ42643" ENSG00000166448 "Transmembrane protein 130" Q8N3G9 7 98846488-98870771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 164.8;pituitary gland: 97.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 44.1;Excitatory neurons: 42.3;Horizontal cells: 14.5;Inhibitory neurons: 51.6;Oligodendrocyte precursor cells: 10.8" "Cancer enhanced" "Detected in many" "renal cancer: 9.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.7" "Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012928 Uncertain Supported "Golgi apparatus" NA NA 9400 "Cluster 5: Brain & Testis - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" 10 "Golgi apparatus" "HPA012928: AB_1858085" "unprognostic (1.36e-2)" "unprognostic (1.33e-3)" "unprognostic (3.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.61e-3)" "unprognostic (3.23e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.07e-2)" "unprognostic (1.17e-2)" "unprognostic (4.69e-2)" "unprognostic (5.65e-2)" "unprognostic (1.86e-3)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (1.17e-2)" "unprognostic (1.73e-1)" TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Intermediate filaments" "HPA017678: AB_1858086, HPA017682: AB_1858087" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (7.42e-2)" "unprognostic (8.58e-2)" "unprognostic (4.18e-2)" "unprognostic (7.59e-3)" "unprognostic (3.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.10e-3)" "unprognostic (5.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.77e-1)" TMEM131L "DKFZp586H1322, KIAA0922" ENSG00000121210 "Transmembrane 131 like" A2VDJ0 4 153466346-153636711 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.9;lymphoid tissue: 47.0" "Cell type enhanced" "Detected in many" "B-cells: 59.9;Excitatory neurons: 43.2;Inhibitory neurons: 59.3;Late spermatids: 59.5;Oligodendrocyte precursor cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 34.5;lymphoma: 59.7" "Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043472, HPA048443" Uncertain Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" Vesicles "Nucleoli fibrillar center" "HPA043472: AB_2678496, HPA048443: AB_2680395" "unprognostic (1.12e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (8.37e-2)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "unprognostic (3.30e-2)" "unprognostic (3.23e-2)" "unprognostic (4.11e-2)" "unprognostic (4.37e-2)" "unprognostic (7.29e-2)" "unprognostic (4.35e-3)" "unprognostic (2.92e-2)" "unprognostic (3.39e-2)" "unprognostic (3.94e-2)" "unprognostic (3.51e-2)" TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 108.6;choroid plexus: 110.3" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Bipolar cells: 78.6;Ductal cells: 77.3;Horizontal cells: 153.6;Muller glia cells: 162.0;Rod photoreceptor cells: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" TMEM132B "KIAA1786, KIAA1906" ENSG00000139364 "Transmembrane protein 132B" Q14DG7 12 125186386-125662377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.9" "Group enriched" "Detected in some" 7 "Astrocytes: 157.0;Excitatory neurons: 417.4;Inhibitory neurons: 461.1;Oligodendrocyte precursor cells: 252.3" "Cancer enriched" "Detected in single" 7 "glioma: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Bone cancer: 7.4" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035661, HPA035662" Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA035661: AB_10669774, HPA035662: AB_2674726" "unprognostic (3.38e-3)" "unprognostic (4.39e-2)" "unprognostic (6.73e-2)" "unprognostic (6.33e-2)" "unprognostic (1.06e-1)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (1.26e-1)" "unprognostic (4.58e-1)" "unprognostic (1.12e-1)" "unprognostic (6.23e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-4)" "unprognostic (1.20e-1)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (3.73e-3)" TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267170-128707911 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.4" "Group enriched" "Detected in many" 4 "Inhibitory neurons: 209.6;Microglial cells: 153.0;Oligodendrocyte precursor cells: 544.8" "Group enriched" "Detected in some" 4 "glioma: 1.6;ovarian cancer: 4.6;testis cancer: 4.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Group enriched" "Detected in some" 5 "Neuroblastoma: 2.7;Rhabdoid: 2.5;Sarcoma: 3.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015633, HPA015984" Uncertain Centrosome,Cytosol NA NA 78000000 "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" Cytosol Centrosome "HPA015633: AB_1858089, HPA015984: AB_1858088" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (7.34e-2)" "unprognostic (8.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.99e-3)" "unprognostic (5.48e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-1)" "unprognostic (5.71e-2)" "unprognostic (6.33e-3)" TMEM132D "KIAA1944, MOLT, PPP1R153" ENSG00000151952 "Transmembrane protein 132D" Q14C87 12 129071725-129904025 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 7.1" "Group enriched" "Detected in some" 60 "Excitatory neurons: 433.7;Inhibitory neurons: 498.9;Oligodendrocyte precursor cells: 537.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010739 Approved NA NA 110000 "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 65: Neurons - Synaptic function" 1 "HPA010739: AB_2204753" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (5.39e-1)" "unprognostic (1.47e-2)" "unprognostic (2.89e-1)" "unprognostic (3.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.31e-4)" TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 16.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.9;Horizontal cells: 8.8;Inhibitory neurons: 6.1;Oligodendrocyte precursor cells: 12.3;Proximal tubular cells: 11.6;Schwann cells: 3.4" "Cancer enriched" "Detected in some" 4 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 170000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: AB_2686286" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-5)" "unprognostic (3.37e-1)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-3)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 7: Non-specific - Ribosome" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 115.5;Excitatory neurons: 96.2;Inhibitory neurons: 89.8;Oligodendrocyte precursor cells: 115.6;Oligodendrocytes: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Endothelial cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61361964-61377890 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 85.0;Rod photoreceptor cells: 196.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042373 Approved Approved Microtubules NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" Microtubules "HPA042373: AB_10793880" "unprognostic (1.30e-1)" "unprognostic (4.69e-3)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.15e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.49e-1)" "unprognostic (4.46e-1)" TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.9;kidney: 31.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 37.3;Collecting duct cells: 50.6;Distal enterocytes: 44.5;Ductal cells: 43.3;Proximal enterocytes: 85.8;Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 35 "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 802.8;Paneth cells: 667.8;Proximal enterocytes: 646.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" TMEM143 FLJ10922 ENSG00000161558 "Transmembrane protein 143" Q96AN5 19 48332356-48364059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 42.2;skeletal muscle: 92.1;tongue: 58.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014476, HPA058645" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "Nucleoli fibrillar center" "HPA014476: AB_1858092, HPA058645: " "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (5.23e-2)" "unprognostic (2.50e-1)" "unprognostic (5.94e-2)" "unprognostic (2.11e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (4.08e-1)" "unprognostic (2.25e-1)" "unprognostic (7.29e-2)" "unprognostic (9.82e-2)" "prognostic favorable (1.53e-7)" "unprognostic (5.46e-2)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-1)" TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 164.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 925.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 5 Mitochondria "HPA063554: AB_2685039" "unprognostic (1.26e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-2)" "prognostic favorable (2.89e-4)" "unprognostic (2.90e-1)" "unprognostic (1.71e-5)" "unprognostic (8.27e-2)" "unprognostic (3.32e-1)" "unprognostic (2.21e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (9.34e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (3.88e-2)" "unprognostic (4.05e-2)" TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 204.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 49.8;Cone photoreceptor cells: 25.5;Excitatory neurons: 25.6;Horizontal cells: 77.4;Inhibitory neurons: 52.1;Rod photoreceptor cells: 28.2" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 5.0;neutrophil: 13.6" "Lineage enriched" "Detected in many" 11 "granulocytes: 13.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.6" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" TMEM14A "C6orf73, PTD011" ENSG00000096092 "Transmembrane protein 14A" Q9Y6G1 6 52671113-52686588 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072536 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 21 "Nucleoplasm, Endoplasmic reticulum" "HPA072536: AB_2686531" "unprognostic (6.75e-2)" "unprognostic (3.65e-2)" "unprognostic (2.04e-1)" "unprognostic (8.10e-3)" "unprognostic (3.55e-2)" "unprognostic (1.06e-1)" "unprognostic (8.05e-2)" "unprognostic (4.10e-2)" "unprognostic (1.45e-1)" "unprognostic (2.56e-3)" "unprognostic (8.88e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-2)" "unprognostic (9.60e-2)" "unprognostic (5.44e-2)" "unprognostic (3.37e-1)" "unprognostic (2.64e-1)" TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 138.2;Early spermatids: 125.8;Late spermatids: 91.3;Syncytiotrophoblasts: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 "HPA019015: AB_2204758" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-3)" "unprognostic (4.09e-3)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-2)" "unprognostic (5.80e-2)" "unprognostic (2.64e-2)" "unprognostic (2.54e-3)" "unprognostic (7.16e-2)" "unprognostic (8.27e-3)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (6.87e-3)" TMEM150C "FLJ12993, TTN3" ENSG00000249242 "Transmembrane protein 150C" B9EJG8 4 82483170-82562357 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 131.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.2;Syncytiotrophoblasts: 113.3" "Cancer enhanced" "Detected in all" "breast cancer: 23.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 12.3" "Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052921 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA052921: AB_2681988" "unprognostic (2.99e-1)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.89e-3)" "unprognostic (1.71e-3)" "prognostic favorable (7.87e-4)" "unprognostic (2.94e-2)" "unprognostic (5.55e-2)" "unprognostic (1.06e-1)" "unprognostic (3.94e-2)" "prognostic favorable (5.68e-4)" "unprognostic (4.57e-2)" "prognostic favorable (4.59e-6)" "unprognostic (4.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" TMEM151A "MGC33486, TMEM151" ENSG00000179292 "Transmembrane protein 151A" Q8N4L1 11 66291894-66296664 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 131.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.2;Horizontal cells: 18.3;Inhibitory neurons: 10.5;Mesothelial cells: 28.8;Oligodendrocytes: 65.2" "Cancer enhanced" "Detected in some" "glioma: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041035 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoli Cytosol "HPA041035: AB_10794404" "unprognostic (1.20e-1)" "unprognostic (8.24e-3)" "unprognostic (4.80e-2)" "unprognostic (1.75e-2)" "unprognostic (3.44e-1)" "unprognostic (7.60e-2)" "unprognostic (9.48e-3)" "unprognostic (8.57e-2)" "unprognostic (8.73e-4)" "unprognostic (2.41e-3)" "unprognostic (2.02e-2)" "unprognostic (6.11e-3)" "unprognostic (1.69e-3)" "unprognostic (2.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.38e-2)" "unprognostic (2.67e-2)" TMEM151B "bA444E17.5, C6orf137, TMEM193" ENSG00000178233 "Transmembrane protein 151B" Q8IW70 6 44270450-44307506 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "brain: 139.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 26.2;Horizontal cells: 12.6;Inhibitory neurons: 30.1" "Cancer enhanced" "Detected in single" "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 26.5" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055167 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA055167: AB_2682723" "unprognostic (1.28e-3)" "unprognostic (6.25e-2)" "unprognostic (5.06e-2)" "unprognostic (7.02e-3)" "unprognostic (6.61e-2)" "unprognostic (1.22e-3)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-4)" "unprognostic (1.48e-1)" "unprognostic (4.56e-3)" "unprognostic (1.85e-1)" "unprognostic (9.15e-2)" "unprognostic (3.86e-2)" "unprognostic (1.66e-1)" TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.1;skin 1: 47.1" "Cell type enhanced" "Detected in many" "B-cells: 106.2;Basal keratinocytes: 82.2;Glandular and luminal cells: 75.0;granulocytes: 134.3;monocytes: 75.9;Squamous epithelial cells: 108.1;Suprabasal keratinocytes: 306.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 36.8;eosinophil: 20.8;neutrophil: 35.9" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.8" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 59: Suprabasal keratinocytes - Cornification" 9 "Nuclear membrane" Nucleoplasm "HPA019184: AB_2670088, HPA055411: " "unprognostic (1.09e-1)" "unprognostic (3.56e-1)" "unprognostic (5.17e-2)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.65e-1)" "unprognostic (5.00e-3)" "unprognostic (7.67e-2)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" TMEM158 "p40BBp, RIS1" ENSG00000249992 "Transmembrane protein 158" Q8WZ71 3 45224466-45226287 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 82.6;endometrium 1: 67.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.0;Breast myoepithelial cells: 25.9;Endometrial stromal cells: 60.6;Muller glia cells: 75.4" "Cancer enhanced" "Detected in many" "glioma: 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 58.8" "Pancreas - Ductal cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "basal ganglia: 95.5" "Low region specificity" "Detected in all" HPA074974 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 10: Muller glia cells - Visual perception" "HPA074974: AB_2732274" "unprognostic (3.84e-1)" "unprognostic (9.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.77e-2)" "unprognostic (5.73e-2)" "unprognostic (3.31e-2)" "unprognostic (4.67e-3)" "unprognostic (6.23e-2)" "unprognostic (6.41e-2)" "unprognostic (1.84e-3)" "prognostic favorable (6.43e-5)" "prognostic unfavorable (5.42e-9)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-2)" "unprognostic (4.49e-3)" TMEM160 FLJ20512 ENSG00000130748 "Transmembrane protein 160" Q9NX00 19 47045909-47048624 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055904 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 2 "HPA055904: AB_2682965" "unprognostic (2.45e-3)" "unprognostic (1.69e-1)" "unprognostic (4.49e-1)" "unprognostic (1.09e-2)" "unprognostic (3.71e-1)" "unprognostic (7.39e-2)" "unprognostic (3.60e-1)" "unprognostic (3.20e-2)" "unprognostic (6.58e-2)" "unprognostic (2.86e-1)" "unprognostic (8.21e-3)" "unprognostic (3.76e-2)" "unprognostic (1.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.03e-1)" "unprognostic (1.86e-2)" "unprognostic (1.37e-2)" TMEM161A "FLJ20422, FLJ39645" ENSG00000064545 "Transmembrane protein 161A" Q9NX61 19 19119169-19138513 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043365 Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 9: Endometrial stromal cells - Transcription" 2 Cytosol "HPA043365: AB_10796793" "unprognostic (4.31e-2)" "unprognostic (9.13e-2)" "unprognostic (2.34e-2)" "unprognostic (7.42e-3)" "unprognostic (6.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-2)" "unprognostic (3.51e-2)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (9.42e-2)" "unprognostic (2.46e-1)" "unprognostic (9.15e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.18e-1)" "unprognostic (2.79e-1)" "unprognostic (4.89e-3)" TMEM161B MGC33214 ENSG00000164180 "Transmembrane protein 161B" Q8NDZ6 5 88189633-88269476 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044562 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 55: Non-specific - Transcription" "HPA044562: AB_10794291" "unprognostic (2.08e-1)" "unprognostic (6.02e-2)" "unprognostic (2.06e-2)" "unprognostic (5.64e-2)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" "unprognostic (3.07e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-1)" "unprognostic (1.01e-1)" "unprognostic (6.96e-3)" "unprognostic (1.55e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-3)" "unprognostic (9.35e-2)" TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.4;pancreas: 27.0" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 54.1;Excitatory neurons: 60.1;Oligodendrocyte precursor cells: 206.1;Oocytes: 193.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.3" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.9;Astrocytes: 80.2;Distal enterocytes: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Astrocytes - Unknown function" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" TMEM165 "GDT1, SLC64A1, TMPT27, TPARL" ENSG00000134851 "Transmembrane protein 165" Q9HC07 4 55395957-55453397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 950.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038299, HPA062424" Supported Enhanced "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: Respiratory epithelial cells - Unknown function" "Golgi apparatus" "HPA038299: AB_10675793, HPA062424: AB_2732682" "unprognostic (2.53e-2)" "unprognostic (1.08e-3)" "unprognostic (3.46e-3)" "unprognostic (7.07e-3)" "unprognostic (5.97e-2)" "unprognostic (9.84e-2)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (8.00e-3)" "unprognostic (1.55e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.18e-8)" "unprognostic (9.05e-2)" "unprognostic (8.96e-2)" "unprognostic (2.72e-1)" "unprognostic (2.18e-2)" TMEM167A "FLJ30508, MGC23909, TMEM167" ENSG00000174695 "Transmembrane protein 167A" Q8TBQ9 5 83052846-83077863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 350.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077278 Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Monocytes - Innate immune response" 1 Vesicles "HPA077278: " "unprognostic (5.38e-3)" "unprognostic (2.84e-3)" "unprognostic (3.78e-2)" "unprognostic (4.40e-2)" "unprognostic (1.66e-1)" "unprognostic (3.34e-1)" "unprognostic (4.06e-3)" "unprognostic (7.74e-2)" "unprognostic (9.94e-3)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (4.09e-2)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (1.13e-3)" "unprognostic (1.29e-2)" TMEM168 DKFZp564C012,FLJ13576 ENSG00000146802 "Transmembrane protein 168" Q9H0V1 7 112762377-112790423 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020389, HPA077143" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Non-specific - Transcription" 1 "Golgi apparatus" Cytosol "HPA020389: AB_1858101, HPA077143: " "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (2.55e-1)" "unprognostic (4.92e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-2)" "unprognostic (2.30e-3)" "prognostic favorable (4.07e-6)" "unprognostic (1.60e-3)" "unprognostic (8.73e-2)" "unprognostic (3.07e-3)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.47e-1)" "unprognostic (1.84e-1)" "unprognostic (4.89e-3)" "unprognostic (3.30e-2)" TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.2;retina: 3.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Cone photoreceptor cells: 18.7;Excitatory neurons: 12.6;Inhibitory neurons: 13.4;Oligodendrocyte precursor cells: 10.4;Oligodendrocytes: 8.7;Rod photoreceptor cells: 11.2" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 19.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA070657, HPA074877" Enhanced Approved "Focal adhesion sites" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Focal adhesion sites" "HPA070657: AB_2686293, HPA074877: " "unprognostic (5.15e-2)" "unprognostic (2.93e-1)" "unprognostic (7.87e-3)" "unprognostic (4.69e-7)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.43e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (4.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" TMEM17 FLJ34583 ENSG00000186889 "Transmembrane protein 17" Q86X19 2 62500218-62511894 "Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 39.1;Spermatogonia: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018100 Uncertain Uncertain "Actin filaments" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Ciliated cells - Cilium assembly" 4 "Actin filaments" "HPA018100: AB_2240686" "unprognostic (8.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (5.02e-3)" "unprognostic (3.78e-1)" "unprognostic (1.87e-4)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (3.44e-2)" "unprognostic (2.26e-1)" "unprognostic (2.36e-1)" "unprognostic (7.68e-3)" "unprognostic (1.11e-2)" "unprognostic (3.06e-2)" "unprognostic (3.62e-1)" "unprognostic (1.49e-6)" TMEM170B ENSG00000205269 "Transmembrane protein 170B" Q5T4T1 6 11537749-11583524 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.9" "Cell type enhanced" "Detected in many" "Astrocytes: 37.2;dendritic cells: 32.0;Excitatory neurons: 55.4;Inhibitory neurons: 50.1;Kupffer cells: 42.0;Macrophages: 34.9;monocytes: 106.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.5" "Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055134 Uncertain Approved Centrosome NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Centrosome "HPA055134: AB_2682709" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.71e-4)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (4.62e-3)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (2.45e-5)" "unprognostic (3.49e-1)" "unprognostic (1.26e-1)" "unprognostic (4.27e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-4)" "unprognostic (3.97e-2)" TMEM171 PRP2 ENSG00000157111 "Transmembrane protein 171" Q8WVE6 5 73120569-73131809 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 34.4;kidney: 10.4;lymphoid tissue: 14.0;stomach 1: 24.7;thyroid gland: 30.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.6;Cholangiocytes: 34.3;Distal enterocytes: 98.6;Paneth cells: 53.8;Proximal enterocytes: 45.5;Undifferentiated cells: 49.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 24.1;memory CD8 T-cell: 8.2" "Lineage enriched" "Detected in single" 89 "T-cells: 24.1" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Colon - Colon enterocytes, Stomach - Parietal cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.9" HPA042308 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "HPA042308: AB_10796901" "unprognostic (7.34e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (7.74e-3)" "unprognostic (2.81e-5)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-3)" "unprognostic (1.77e-1)" "unprognostic (1.85e-1)" "unprognostic (4.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (3.93e-10)" "unprognostic (6.13e-3)" "unprognostic (2.43e-1)" "unprognostic (9.10e-3)" "unprognostic (1.57e-1)" TMEM174 "FLJ31268, MGC13034" ENSG00000164325 "Transmembrane protein 174" Q8WUU8 5 73173193-73175143 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 800 "kidney: 147.7" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 117.5" "Cancer enriched" "Detected in single" 126 "renal cancer: 6.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037975 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 22: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 12 "HPA037975: AB_10672732" "unprognostic (8.11e-2)" "prognostic favorable (3.30e-6)" TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" "HPA057160: AB_2683356" "unprognostic (3.84e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-2)" "unprognostic (9.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (1.12e-2)" "unprognostic (3.25e-3)" "unprognostic (1.22e-2)" "unprognostic (1.50e-2)" "prognostic favorable (9.85e-5)" "unprognostic (4.71e-2)" "unprognostic (5.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (1.96e-1)" "unprognostic (7.51e-3)" TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 363.1;liver: 1133.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1025.8;Paneth cells: 727.3;Proximal enterocytes: 1314.4;Proximal tubular cells: 874.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.6;intermediate monocyte: 98.5" "Lineage enriched" "Detected in many" 5 "monocytes: 146.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.1;Gastric cancer: 31.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 12 Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1609.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 1117.7;Paneth cells: 750.0;Proximal enterocytes: 925.4;Proximal tubular cells: 740.7;Schwann cells: 424.7" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 866.3;intermediate monocyte: 586.7" "Lineage enriched" "Detected in many" 5 "monocytes: 866.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.7" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 4 "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Distal tubular cells: 43.0;Proximal tubular cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (1.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (9.81e-3)" "unprognostic (2.05e-3)" "unprognostic (3.17e-2)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (4.90e-1)" "unprognostic (6.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 384.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 37.8;Excitatory neurons: 105.2;Horizontal cells: 32.1;Inhibitory neurons: 104.8;Oligodendrocyte precursor cells: 31.6" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 18.8;testis cancer: 21.8" "Colon - Enteric glia cells, Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;heart muscle: 10.2;parathyroid gland: 11.5;tongue: 11.6" "Group enriched" "Detected in many" 5 "Astrocytes: 166.0;Excitatory neurons: 565.6;Inhibitory neurons: 542.7;Oligodendrocyte precursor cells: 287.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" TMEM179 "C14orf90, FLJ42486, TMEM179A" ENSG00000258986 "Transmembrane protein 179" Q6ZVK1 14 104474678-104605647 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 71.3;pituitary gland: 85.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 44.7;Excitatory neurons: 11.6;Horizontal cells: 41.5;Inhibitory neurons: 11.7;Oligodendrocyte precursor cells: 7.1" "Group enriched" "Detected in some" 4 "glioma: 2.7;pancreatic cancer: 3.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.9;prostate cancer: 16.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002942 Uncertain Mitochondria NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Mitochondria "HPA002942: AB_1078113" "unprognostic (8.65e-2)" "unprognostic (8.24e-2)" "unprognostic (3.10e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.82e-3)" "unprognostic (1.09e-1)" "unprognostic (1.89e-4)" "unprognostic (8.68e-3)" "unprognostic (1.56e-1)" "unprognostic (9.71e-6)" "unprognostic (1.70e-2)" TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 45 "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" TMEM18 "DKFZp434C1714, lncND" ENSG00000151353 "Transmembrane protein 18" Q96B42 2 663877-677406 "Predicted membrane proteins, Transporters" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040233 Approved Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 18: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 6: Ovarian stromal cells - Transcription" Mitochondria "Endoplasmic reticulum" "HPA040233: AB_10794737" "unprognostic (9.01e-3)" "unprognostic (2.45e-1)" "unprognostic (7.48e-2)" "unprognostic (1.77e-3)" "unprognostic (2.68e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-2)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (6.05e-2)" "unprognostic (1.86e-1)" "unprognostic (9.45e-2)" "unprognostic (8.20e-2)" "unprognostic (2.49e-1)" "unprognostic (3.65e-1)" "unprognostic (4.98e-3)" "unprognostic (8.08e-2)" TMEM181 "GPR178, KIAA1423" ENSG00000146433 "Transmembrane protein 181" Q9P2C4 6 158536436-158635429 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 102.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040189 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Vesicles "Golgi apparatus" "HPA040189: AB_10793959" "unprognostic (1.93e-2)" "prognostic unfavorable (7.26e-4)" "unprognostic (9.87e-2)" "unprognostic (6.51e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (4.07e-2)" "unprognostic (1.46e-1)" "unprognostic (1.93e-1)" "unprognostic (4.36e-1)" "unprognostic (3.26e-1)" TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" Myogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "heart muscle: 94.2;skeletal muscle: 145.3;tongue: 122.8" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 182.9;Skeletal myocytes: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" TMEM183A C1orf37 ENSG00000163444 "Transmembrane protein 183A" Q8IXX5 1 203007374-203024848 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072607 Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA072607: AB_2686539" "unprognostic (2.94e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.41e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (6.46e-2)" "unprognostic (3.21e-2)" "unprognostic (4.82e-3)" "unprognostic (5.28e-2)" "unprognostic (7.84e-2)" "unprognostic (4.83e-2)" "unprognostic (6.01e-3)" "unprognostic (9.55e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.1;Intestinal goblet cells: 37.4;Proximal enterocytes: 53.1;Suprabasal keratinocytes: 54.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.4;Oligodendrocytes: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 47: Astrocytes - Unknown function" 1 "Golgi apparatus, Cytosol" Nucleoplasm "HPA024076: AB_1858106" "unprognostic (1.52e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-1)" "unprognostic (8.96e-2)" "unprognostic (3.82e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.94e-6)" "unprognostic (1.14e-2)" "unprognostic (5.18e-2)" "unprognostic (4.52e-2)" "unprognostic (9.20e-2)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" TMEM184C "FLJ10846, TMEM34" ENSG00000164168 "Transmembrane protein 184C" Q9NVA4 4 147617386-147672044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 127.3" "Cell type enhanced" "Detected in all" "Early spermatids: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054013 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Vesicles Nucleoplasm "HPA054013: AB_2682343" "unprognostic (5.45e-3)" "unprognostic (2.49e-2)" "unprognostic (3.93e-3)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (7.72e-3)" "unprognostic (1.48e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.37e-4)" "unprognostic (1.13e-1)" "prognostic favorable (2.31e-7)" "unprognostic (4.68e-2)" "unprognostic (3.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.31e-3)" TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" 8 "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" TMEM185B "FAM11B, FLJ20979" ENSG00000226479 "Transmembrane protein 185B" Q9H7F4 2 120217479-120223400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.44e-4)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.35e-2)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.71e-7)" "unprognostic (3.09e-3)" "unprognostic (1.65e-1)" "unprognostic (9.01e-2)" "unprognostic (1.96e-2)" "unprognostic (8.28e-2)" "unprognostic (6.03e-3)" "unprognostic (1.72e-1)" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 38.6;Late spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 4 "Cell Junctions" "HPA018226: AB_1845579, HPA063559: AB_2685041" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "unprognostic (2.98e-2)" "unprognostic (4.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.06e-2)" "unprognostic (9.35e-2)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.93e-8)" "unprognostic (1.06e-1)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" TMEM187 "CXorf12, DXS9878E, ITBA1" ENSG00000177854 "Transmembrane protein 187" Q14656 X 153972754-153983194 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" HPA038134 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 33: Non-specific - DNA binding" 13 "Nucleoli, Cytosol" "HPA038134: AB_10669517" "unprognostic (1.51e-1)" "unprognostic (4.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-2)" "unprognostic (8.94e-2)" "unprognostic (2.41e-1)" "unprognostic (3.09e-1)" "unprognostic (4.22e-2)" "unprognostic (5.33e-2)" "unprognostic (7.41e-2)" "prognostic favorable (9.14e-8)" "unprognostic (6.73e-2)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (7.04e-2)" TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 73: B-cells - B-cell function" 34 "HPA016830: AB_1858107" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (6.76e-2)" "unprognostic (1.44e-1)" "unprognostic (4.45e-1)" "unprognostic (3.43e-2)" "unprognostic (7.60e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-2)" "unprognostic (4.42e-1)" "unprognostic (5.32e-3)" "unprognostic (1.00e-1)" TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 6: Ovarian stromal cells - Transcription" "Endosomes, Lysosomes" Nucleoplasm "HPA014717: AB_1844373, HPA024110: AB_2204898" "prognostic unfavorable (9.52e-4)" "unprognostic (5.38e-3)" "unprognostic (9.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (2.91e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (3.10e-1)" "unprognostic (3.27e-2)" "unprognostic (5.06e-2)" "prognostic favorable (2.33e-14)" "unprognostic (2.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (9.30e-2)" TMEM196 MGC42090 ENSG00000173452 "Transmembrane protein 196" Q5HYL7 7 19719315-19773617 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4;retina: 20.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 106.2;Endometrial stromal cells: 97.1;Excitatory neurons: 43.5;Oligodendrocyte precursor cells: 119.8" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" HPA043163 Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Golgi apparatus" "HPA043163: AB_10794772" "unprognostic (6.08e-3)" "unprognostic (1.88e-2)" "unprognostic (2.14e-2)" "unprognostic (9.30e-2)" "unprognostic (5.63e-2)" TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 13.9;Horizontal cells: 18.3;Muller glia cells: 11.5;Proximal enterocytes: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" TMEM199 "C17orf32, MGC45714, VMA12, VPH2" ENSG00000244045 "Transmembrane protein 199" Q8N511 17 28357642-28363683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027051 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 15 "HPA027051: AB_10600915" "unprognostic (3.01e-1)" "unprognostic (3.45e-2)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.55e-4)" "unprognostic (9.98e-2)" "unprognostic (4.60e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.67e-2)" "unprognostic (5.26e-2)" "unprognostic (1.78e-1)" "unprognostic (6.38e-3)" "unprognostic (1.09e-1)" "unprognostic (9.25e-2)" "unprognostic (2.75e-1)" "unprognostic (1.99e-1)" "unprognostic (3.51e-3)" "unprognostic (5.95e-2)" TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 38.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.5;Distal enterocytes: 12.4;Endometrial stromal cells: 17.3;Enteroendocrine cells: 16.0;Peritubular cells: 10.8;Skeletal myocytes: 10.7" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 58.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.6;Fibroblasts: 7.5;Leydig cells: 12.8;Lymphatic endothelial cells: 6.7;Ovarian stromal cells: 9.7;Peritubular cells: 13.9;Sertoli cells: 8.2;Smooth muscle cells: 10.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 12.2" HPA055254 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" TMEM200C TTMA ENSG00000206432 "Transmembrane protein 200C" A6NKL6 18 5882072-5895955 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.8;brain: 3.4;salivary gland: 5.3" "Cell type enhanced" "Detected in some" "Horizontal cells: 17.6;Inhibitory neurons: 7.6;Mucus glandular cells: 10.5;Oligodendrocyte precursor cells: 16.5" "Cancer enhanced" "Detected in single" "glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 3.5" "Kidney - Podocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047253, HPA050490" Uncertain Approved Microtubules NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" Microtubules "HPA047253: AB_2680001, HPA050490: AB_2681144" "unprognostic (6.57e-4)" "unprognostic (3.09e-1)" "unprognostic (1.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.29e-2)" "unprognostic (6.31e-2)" "unprognostic (3.82e-4)" "unprognostic (2.48e-10)" "unprognostic (2.94e-2)" "unprognostic (6.38e-2)" "unprognostic (7.22e-2)" "unprognostic (2.38e-2)" TMEM201 "Ima1, NET5, RP13-15M17.2, SAMP1" ENSG00000188807 "Transmembrane protein 201" Q5SNT2 1 9588911-9614877 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.3;Cone photoreceptor cells: 20.4;Rod photoreceptor cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB039039 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 37: Non-specific - mRNA processing" "Cluster 25: Bipolar cells - Visual perception" "Nuclear membrane" Nucleoplasm "CAB039039: " "unprognostic (1.75e-2)" "prognostic favorable (5.36e-4)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (4.88e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (9.61e-8)" "unprognostic (2.22e-1)" "unprognostic (3.60e-1)" "unprognostic (3.87e-2)" "unprognostic (5.59e-3)" "unprognostic (1.63e-1)" "unprognostic (9.38e-2)" "unprognostic (3.87e-2)" "unprognostic (6.25e-2)" "unprognostic (7.99e-2)" "unprognostic (1.45e-1)" TMEM204 "C16orf30, CLP24, FLJ20898" ENSG00000131634 "Transmembrane protein 204" Q9BSN7 16 1528688-1555580 "Predicted membrane proteins, Transporters" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 187.7;Endothelial cells: 97.0;Fibroblasts: 43.4;Lymphatic endothelial cells: 47.7;Peritubular cells: 64.5;Sertoli cells: 43.5;Smooth muscle cells: 47.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 157.0" "Lineage enriched" "Detected in many" 5 "T-cells: 157.0" "Cancer enhanced" "Detected in many" "Sarcoma: 7.4;skin cancer: 7.2" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014028 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA014028: AB_2204906" "unprognostic (1.51e-1)" "unprognostic (6.35e-2)" "unprognostic (3.81e-3)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-2)" "prognostic favorable (4.76e-4)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (8.44e-2)" "unprognostic (2.95e-2)" "unprognostic (4.04e-2)" "unprognostic (7.62e-3)" "unprognostic (5.11e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (2.53e-2)" TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 499.3;Late spermatids: 708.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 43: Hepatocytes - Metabolism" 15 "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" TMEM207 ENSG00000198398 "Transmembrane protein 207" Q6UWW9 3 190428655-190449901 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "kidney: 17.1" "Cell type enriched" "Detected in single" 38 "Distal tubular cells: 36.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014332 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" 9 "HPA014332: AB_2204907" "unprognostic (4.81e-2)" TMEM208 "hSND2, HSPC171" ENSG00000168701 "Transmembrane protein 208" Q9BTX3 16 67227103-67229278 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041868, HPA041949" Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 77: Plasma cells - Protein processing" 18 "HPA041868: AB_10962347, HPA041949: AB_10959903" "unprognostic (9.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.36e-3)" "unprognostic (2.05e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.44e-1)" "unprognostic (6.53e-2)" "unprognostic (6.40e-2)" "unprognostic (1.31e-2)" "unprognostic (2.29e-1)" "unprognostic (5.18e-2)" "unprognostic (7.73e-2)" "unprognostic (9.42e-2)" TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: AB_10603135" "unprognostic (3.03e-1)" "unprognostic (5.06e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (5.98e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (3.19e-1)" "unprognostic (6.00e-2)" "unprognostic (2.34e-3)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.68e-2)" "unprognostic (3.24e-1)" TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.4" "Group enriched" "Detected in some" 84 "Early spermatids: 882.8;Late spermatids: 1829.4" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.3" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.3" "Cancer enhanced" "Detected in single" "prostate cancer: 2.0" "Breast - Breast glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 42: Testis - Spermatogenesis" "Cluster 60: Prostate cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" TMEM212 FLJ23172 ENSG00000186329 "Transmembrane protein 212" A6NML5 3 171843349-171938715 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 29.1" "Cell type enriched" "Detected in some" 10 "Ciliated cells: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045736 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 59: Fallopian tube - Tissue development" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA045736: AB_2679436" "unprognostic (3.39e-2)" "unprognostic (1.78e-2)" "unprognostic (3.05e-1)" "unprognostic (5.54e-2)" "unprognostic (3.06e-1)" "unprognostic (2.87e-1)" TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "kidney: 73.2;salivary gland: 50.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 48.6;Distal tubular cells: 162.9;Salivary duct cells: 56.5;Serous glandular cells: 35.1" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 1.9" "Group enriched" "Detected in some" 4 "Gastric cancer: 1.2;Sarcoma: 1.4" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054059 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "retina: 17.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 572.6;Late spermatids: 347.7" "Cancer enriched" "Detected in single" 14 "thyroid cancer: 4.9" "Region enhanced" "Detected in many" "hypothalamus: 13.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA063207 Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA063207: AB_2732697" "unprognostic (1.31e-2)" "unprognostic (4.57e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (5.85e-2)" "unprognostic (4.38e-3)" "unprognostic (2.17e-3)" "unprognostic (2.82e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.32e-2)" TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212180-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.7" "Cell type enhanced" "Detected in many" "Ductal cells: 10.8;Exocrine glandular cells: 12.7;Mucus glandular cells: 27.1;Spermatocytes: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" Nucleoli Cytosol "HPA045432: AB_2732519, HPA071187: AB_2732174" "unprognostic (7.78e-2)" "unprognostic (5.49e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-1)" "unprognostic (6.77e-3)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" "unprognostic (4.23e-4)" "unprognostic (8.22e-2)" "unprognostic (2.18e-1)" "unprognostic (5.62e-2)" "unprognostic (7.26e-2)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (1.59e-1)" TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125094389-125111763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 61 "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" TMEM219 IGFBP-3R ENSG00000149932 "Transmembrane protein 219" Q86XT9 16 29940885-29973050 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 631.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059185 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 7: Non-specific - Ribosome" "Cluster 54: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA059185: AB_2683941" "unprognostic (4.13e-2)" "unprognostic (1.94e-3)" "unprognostic (1.51e-1)" "prognostic favorable (5.79e-4)" "unprognostic (2.62e-1)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (9.83e-2)" "unprognostic (8.53e-2)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-3)" TMEM221 ENSG00000188051 "Transmembrane protein 221" A6NGB7 19 17435509-17448668 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 7.6;retina: 9.1" "Group enriched" "Detected in some" 6 "Muller glia cells: 44.5;Rod photoreceptor cells: 26.4;Secretory cells: 11.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Thyroid - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041580, HPA062945" Supported Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 35: RS4;11 - Unknown function" "Cluster 10: Muller glia cells - Visual perception" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA041580: AB_10795700, HPA062945: " "unprognostic (3.60e-2)" "unprognostic (7.86e-2)" "unprognostic (4.51e-4)" "unprognostic (2.09e-2)" "unprognostic (2.61e-2)" "unprognostic (9.14e-3)" "unprognostic (3.19e-1)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.20e-2)" "unprognostic (1.98e-1)" "unprognostic (9.47e-4)" "unprognostic (2.37e-2)" "unprognostic (6.67e-2)" "unprognostic (2.76e-1)" "unprognostic (2.42e-2)" "unprognostic (1.23e-1)" TMEM222 "C1orf160, DKFZP564D0478" ENSG00000186501 "Transmembrane protein 222" Q9H0R3 1 27322145-27336400 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016579, HPA059374" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Late spermatids - Unknown function" 30 "Plasma membrane, Cytosol" "Cell Junctions" "HPA016579: AB_2669392, HPA059374: AB_2683995" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-3)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (4.11e-2)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "unprognostic (1.96e-2)" "unprognostic (2.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-3)" "unprognostic (5.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.83e-2)" "unprognostic (7.80e-2)" TMEM223 "MGC3196, Mrx15" ENSG00000168569 "Transmembrane protein 223" A0PJW6 11 62771629-62792006 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014504 Approved Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA014504: AB_1853881" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (3.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-3)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (7.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.14e-3)" "unprognostic (9.75e-2)" TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;intestine: 8.2;testis: 5.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Cytotrophoblasts: 2.8;Horizontal cells: 5.0;Oligodendrocytes: 10.6;Proximal enterocytes: 9.9;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Bone cancer: 9.8;Neuroblastoma: 11.4" "Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "HPA056391: AB_2683114" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.89e-2)" "unprognostic (8.21e-2)" "unprognostic (4.74e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" TMEM229B "C14orf83, FLJ33387" ENSG00000198133 "Transmembrane protein 229B" Q8NBD8 14 67447084-67533739 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Cell type enhanced" "Detected in many" "Late spermatids: 28.1;Oligodendrocyte precursor cells: 17.9;Proximal enterocytes: 11.9" "Cancer enhanced" "Detected in all" "melanoma: 12.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 19.3" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046562 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" 34 "HPA046562: AB_10960265" "prognostic favorable (5.38e-4)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.21e-5)" "unprognostic (7.37e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (2.01e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (1.95e-2)" "unprognostic (5.18e-1)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.79e-5)" TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556289 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "choroid plexus: 39.3;fallopian tube: 71.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 130.5;Rod photoreceptor cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved Vesicles NA NA "Cluster 18: Non-specific - Translation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium assembly" 7 Vesicles "HPA042081: AB_10795391" "unprognostic (4.29e-2)" "unprognostic (9.84e-2)" "unprognostic (8.07e-2)" "unprognostic (2.71e-3)" "unprognostic (1.03e-1)" "unprognostic (9.34e-2)" "unprognostic (2.90e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (1.69e-2)" "unprognostic (3.34e-3)" "unprognostic (7.84e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" TMEM232 FLJ43080 ENSG00000186952 "Transmembrane protein 232" C9JQI7 5 110289233-110738956 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "fallopian tube: 13.9;testis: 16.4" "Cell type enhanced" "Detected in many" "Astrocytes: 146.8;Ciliated cells: 89.7;Early spermatids: 158.5;Excitatory neurons: 250.0;Inhibitory neurons: 167.6;Late spermatids: 65.4;Spermatocytes: 71.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049386 Uncertain NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA049386: AB_2680739" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (7.27e-2)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.49e-2)" "unprognostic (9.88e-2)" "unprognostic (1.91e-1)" "unprognostic (1.22e-1)" "unprognostic (6.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.32e-5)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (3.14e-4)" "unprognostic (8.96e-2)" TMEM233 "DSPB2, IFITMD2" ENSG00000224982 "Transmembrane protein 233" B4DJY2 12 119593774-119643075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 64.2;tongue: 20.3" "Group enriched" "Detected in some" 5 "granulocytes: 96.5;Sertoli cells: 27.2;Skeletal myocytes: 64.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 12.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 1.5;Brain cancer: 1.5;Sarcoma: 5.7;thyroid cancer: 4.7" "Breast - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047506, HPA075435" Uncertain Approved Nucleoplasm NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 30: Granulocytes - Unknown function" Nucleoplasm "HPA047506: AB_10963068, HPA075435: " "unprognostic (1.46e-2)" "unprognostic (1.16e-2)" "unprognostic (1.39e-3)" "unprognostic (1.03e-2)" "unprognostic (1.99e-3)" "unprognostic (1.71e-2)" "unprognostic (5.86e-2)" "unprognostic (1.55e-2)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (4.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.10e-3)" "unprognostic (2.94e-1)" "unprognostic (4.38e-2)" "unprognostic (3.66e-1)" TMEM234 "C1orf91, dJ622L5.7, FLJ90779, RP4-622L5" ENSG00000160055 "Transmembrane protein 234" Q8WY98 1 32214472-32222359 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015049 Uncertain Approved Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 53: Non-specific - Glycosylation" "Cluster 17: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Late spermatids - Unknown function" 13 Vesicles "HPA015049: AB_1856409" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-3)" "unprognostic (3.09e-1)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.67e-1)" "unprognostic (1.07e-2)" "unprognostic (6.49e-2)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.12e-5)" "unprognostic (1.95e-1)" "unprognostic (2.44e-1)" "unprognostic (7.92e-2)" "unprognostic (2.37e-2)" TMEM235 ENSG00000204278 "Transmembrane protein 235" A6NFC5 17 78231310-78240987 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 18 "brain: 8.5;choroid plexus: 2.9" "Cell type enriched" "Detected in some" 9 "Oligodendrocytes: 100.3" "Cancer enriched" "Detected in single" 15 "glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053939 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" "HPA053939: AB_2682316" "unprognostic (1.47e-1)" "unprognostic (6.91e-3)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 32.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 63.4;Enteroendocrine cells: 25.5;Intestinal goblet cells: 32.8;Paneth cells: 29.4;Proximal enterocytes: 91.3" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 1.3;Rhabdoid: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045096 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 5: Enterocytes - Absorption" 4 "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 75.1" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 132.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052596, HPA054732" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA052596: AB_2681879, HPA054732: AB_2682587" "unprognostic (1.70e-1)" "unprognostic (7.10e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (1.73e-1)" "unprognostic (4.06e-1)" "unprognostic (8.30e-6)" "unprognostic (4.15e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.96e-6)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" TMEM240 "C1orf70, SCA21" ENSG00000205090 "Transmembrane protein 240" Q5SV17 1 1534778-1540624 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 18.7;Excitatory neurons: 14.9;Horizontal cells: 34.0;Inhibitory neurons: 14.4;Muller glia cells: 11.6;Ovarian stromal cells: 10.2" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066721 Supported NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA066721: AB_2732750" "unprognostic (2.24e-1)" "unprognostic (1.87e-1)" "unprognostic (5.52e-5)" "unprognostic (2.31e-1)" "unprognostic (2.47e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (3.85e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "prognostic favorable (2.52e-4)" "unprognostic (9.13e-2)" "unprognostic (7.96e-3)" "unprognostic (9.50e-4)" "unprognostic (2.64e-1)" "unprognostic (8.38e-2)" "unprognostic (1.93e-1)" TMEM241 "C18orf45, FLJ44259, MGC11386" ENSG00000134490 "Transmembrane protein 241" Q24JQ0 18 23197144-23437961 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029489, HPA059922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 34: Neurons - Neuronal signaling" 1 "Golgi apparatus" Vesicles "HPA029489: AB_2673067, HPA059922: AB_2684164" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (7.80e-2)" "unprognostic (1.02e-2)" "unprognostic (1.37e-1)" "unprognostic (6.48e-2)" "unprognostic (1.15e-4)" "unprognostic (7.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-3)" "unprognostic (9.53e-3)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (2.95e-1)" "unprognostic (4.93e-1)" "prognostic unfavorable (5.80e-4)" TMEM242 "BM033, C6orf35" ENSG00000215712 "Transmembrane protein 242" Q9NWH2 6 157289025-157323601 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025764 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 30 "HPA025764: AB_1845742" "unprognostic (5.42e-3)" "unprognostic (6.02e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (6.24e-2)" "unprognostic (2.21e-3)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.85e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.28e-1)" "unprognostic (6.50e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 180.2;Early spermatids: 203.3;Oocytes: 375.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 37 "HPA014918: AB_2067447" "unprognostic (5.14e-3)" "unprognostic (7.27e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.39e-2)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (4.58e-2)" "unprognostic (2.69e-1)" "unprognostic (6.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-2)" "prognostic favorable (9.13e-4)" TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane, Cytosol" "HPA023892: AB_1845828" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (9.58e-2)" "unprognostic (1.63e-1)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.46e-9)" "unprognostic (6.11e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (2.24e-2)" TMEM247 ENSG00000284701 "Transmembrane protein 247" A6NEH6 2 46479565-46484425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 21.2" "Group enriched" "Detected in some" 13 "Early spermatids: 465.7;Late spermatids: 363.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Not detected" "Not detected" HPA079482 Enhanced NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA079482: " TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 1600000 "Cluster 22: Eosinophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 19 Vesicles "HPA016495: AB_1848643" "unprognostic (6.74e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (4.64e-2)" "unprognostic (6.67e-3)" "unprognostic (9.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (9.18e-2)" "unprognostic (2.80e-3)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (8.28e-2)" "unprognostic (5.57e-2)" TMEM249 C8orfK29 ENSG00000261587 "Transmembrane protein 249" Q2WGJ8 8 144352219-144354954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 26.9" "Group enriched" "Detected in some" 8 "Early spermatids: 25.6;Late spermatids: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 3.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078901 Approved NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 13: Spermatids - Transcription" "HPA078901: " "unprognostic (2.23e-1)" "unprognostic (8.91e-3)" "unprognostic (1.72e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.03e-4)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (8.44e-2)" "unprognostic (3.21e-1)" "unprognostic (1.13e-7)" "unprognostic (6.56e-3)" "unprognostic (1.62e-2)" "unprognostic (8.44e-3)" "unprognostic (3.46e-2)" TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 76.5;Proximal enterocytes: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 6900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" TMEM250 "bA83N9.1, C9orf69" ENSG00000238227 "Transmembrane protein 250" H0YL14 9 136114581-136118875 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066070 Supported Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 33: Non-specific - DNA binding" Nucleoplasm "HPA066070: AB_2685608" "unprognostic (2.79e-2)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "prognostic favorable (1.09e-4)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (4.34e-2)" "unprognostic (1.27e-3)" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (6.31e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-2)" "unprognostic (9.33e-3)" "unprognostic (1.09e-2)" "unprognostic (2.41e-2)" "unprognostic (1.64e-1)" TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 58: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" TMEM252 "C9orf71, MGC34760" ENSG00000181778 "Transmembrane protein 252" Q8N6L7 9 68536580-68540883 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 21.4;kidney: 34.4" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 5.6;Proximal enterocytes: 23.1;Proximal tubular cells: 11.2" "Cancer enriched" "Detected in many" 17 "renal cancer: 35.7" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 8 "neutrophil: 4.1" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.1" "Group enriched" "Detected in some" 7 "ovarian cancer: 1.0;Uterine cancer: 2.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA079457 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA079457: " "unprognostic (2.64e-1)" "unprognostic (3.28e-3)" "unprognostic (3.72e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.64e-2)" "unprognostic (6.42e-2)" "prognostic favorable (1.75e-7)" "unprognostic (7.63e-2)" "unprognostic (6.15e-2)" "unprognostic (7.66e-2)" "unprognostic (2.50e-1)" TMEM253 "C14orf176, C14orf95, NCRNA00220" ENSG00000232070 "Transmembrane protein 253" P0C7T8 14 21098811-21103724 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 94.3" "Group enriched" "Detected in some" 6 "Distal enterocytes: 52.8;Proximal enterocytes: 188.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052329, HPA065092" Enhanced NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA052329: AB_2681791, HPA065092: AB_2685420" "unprognostic (7.48e-3)" "unprognostic (1.33e-2)" "unprognostic (7.19e-2)" "unprognostic (3.84e-2)" "unprognostic (1.41e-2)" "unprognostic (1.50e-2)" "unprognostic (2.07e-1)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.28e-2)" "unprognostic (5.46e-2)" "unprognostic (9.93e-2)" "unprognostic (3.59e-1)" "unprognostic (1.80e-1)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 35 "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.4;ovary: 16.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.9;Oligodendrocyte precursor cells: 30.7;Ovarian stromal cells: 4.9;Schwann cells: 13.1" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cancer enhanced" "Detected in many" "Myeloma: 13.1;skin cancer: 11.7" "Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 60.1;Endothelial cells: 84.0;granulocytes: 33.8;Lymphatic endothelial cells: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 5 Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 607.9;Proximal enterocytes: 977.5;Proximal tubular cells: 818.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" TMEM258 "C11orf10, Kud, Kuduk" ENSG00000134825 "Transmembrane protein 258" P61165 11 61768501-61792802 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044602 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 4 Cytosol "Plasma membrane" "HPA044602: AB_10961423" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (7.49e-2)" "unprognostic (4.99e-3)" "unprognostic (9.95e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.24e-1)" "unprognostic (8.48e-2)" "prognostic favorable (4.37e-4)" "unprognostic (1.34e-3)" "unprognostic (7.39e-2)" "unprognostic (4.75e-3)" "unprognostic (2.59e-2)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.58e-1)" TMEM259 "ASBABP1, C19orf6, MBRL, MGC4022" ENSG00000182087 "Transmembrane protein 259" Q4ZIN3 19 1009648-1021179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042669, HPA054801" Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" "Endoplasmic reticulum" "Nuclear speckles" "HPA042669: AB_10794916, HPA054801: AB_2682604" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.12e-2)" "unprognostic (6.87e-3)" "unprognostic (2.77e-2)" "unprognostic (1.23e-1)" "unprognostic (2.20e-1)" "unprognostic (2.74e-1)" "unprognostic (4.85e-3)" "unprognostic (4.07e-2)" "unprognostic (4.81e-2)" "prognostic favorable (8.92e-6)" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (4.10e-3)" TMEM260 "C14orf101, FLJ20392" ENSG00000070269 "Transmembrane protein 260" Q9NX78 14 56488354-56650606 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 38.4" "Cell type enhanced" "Detected in many" "Early spermatids: 94.2;Excitatory neurons: 64.4;Inhibitory neurons: 60.2;Oligodendrocyte precursor cells: 65.6;Oligodendrocytes: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003502 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 59: Fallopian tube - Tissue development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 21: Early spermatids - Spermatogenesis" "HPA003502: AB_1078314" "unprognostic (4.63e-2)" "unprognostic (2.41e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-1)" "unprognostic (3.58e-2)" "unprognostic (2.04e-1)" "prognostic favorable (7.11e-4)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-3)" "unprognostic (3.22e-1)" "unprognostic (2.23e-3)" "unprognostic (5.81e-2)" "unprognostic (8.11e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.3;skeletal muscle: 5.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 17.0;Cytotrophoblasts: 13.4;Excitatory neurons: 22.2;Inhibitory neurons: 24.0;Late spermatids: 19.9;Oocytes: 30.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in all" 5 "cerebellum: 29.6" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" TMEM267 "C5orf28, FLJ21657" ENSG00000151881 "Transmembrane protein 267" Q0VDI3 5 43444252-43483893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 37.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059946, HPA072991" Approved Nucleoplasm,Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 6 Nucleoplasm Vesicles "HPA059946: AB_2684175, HPA072991: " "unprognostic (8.20e-2)" "unprognostic (2.02e-2)" "unprognostic (7.60e-2)" "unprognostic (8.11e-3)" "unprognostic (1.57e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.82e-2)" "unprognostic (4.77e-3)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.35e-1)" "unprognostic (1.07e-2)" "unprognostic (4.40e-3)" TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 23.5;Excitatory neurons: 24.1;Prostatic glandular cells: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 28: Dendritic cells - Antigen presentation" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 216 "testis: 75.4" "Group enriched" "Detected in some" 185 "Early spermatids: 894.6;Late spermatids: 429.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 10: Testis - Spermatid development" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA077196: AB_2732334" "unprognostic (3.84e-2)" "unprognostic (6.91e-2)" "unprognostic (6.87e-5)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (2.81e-3)" "unprognostic (1.34e-1)" "unprognostic (8.31e-3)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-1)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (7.23e-2)" TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 42.7;Endothelial cells: 46.3;granulocytes: 53.4;Hofbauer cells: 73.9;Langerhans cells: 40.1;Macrophages: 28.1;NK-cells: 27.1;Oligodendrocytes: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.8" "Group enriched" "Detected in some" 7 "Kidney cancer: 10.9;Leukemia: 19.7;lymphoma: 14.3;Myeloma: 6.5" "Breast - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA058166 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" TMEM30A "C6orf67, CDC50A, FLJ10856" ENSG00000112697 "Transmembrane protein 30A" Q9NV96 6 75252924-75284948 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014561 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 9 "HPA014561: AB_10601823" "unprognostic (2.00e-1)" "unprognostic (2.00e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-2)" "unprognostic (3.48e-1)" "unprognostic (1.02e-2)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (4.80e-2)" "unprognostic (1.88e-1)" "unprognostic (5.06e-2)" "unprognostic (7.12e-2)" "unprognostic (8.96e-2)" "unprognostic (1.00e-1)" TMEM30B CDC50B ENSG00000182107 "Transmembrane protein 30B" Q3MIR4 14 61277370-61281761 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043162 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 8 "HPA043162: AB_10796688" "unprognostic (4.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.47e-2)" "unprognostic (2.01e-1)" "unprognostic (6.20e-2)" "unprognostic (2.45e-3)" "unprognostic (3.43e-2)" "unprognostic (9.10e-2)" "unprognostic (2.20e-1)" "unprognostic (5.10e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.89e-5)" "unprognostic (2.21e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (1.85e-1)" TMEM31 MGC39655 ENSG00000179363 "Transmembrane protein 31" Q5JXX7 X 103710909-103714032 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 107.0" "Cell type enriched" "Detected in some" 10 "Late spermatids: 3452.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in all" HPA052760 Approved "Nucleoli fibrillar center" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Nucleoli fibrillar center" "HPA052760: " "unprognostic (9.42e-5)" "unprognostic (1.46e-2)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (7.75e-3)" "unprognostic (1.22e-2)" "unprognostic (2.43e-1)" "unprognostic (4.50e-2)" "unprognostic (1.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.39e-2)" "unprognostic (3.77e-1)" "unprognostic (5.91e-5)" "unprognostic (1.75e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (4.68e-2)" TMEM33 "FLJ10525, Pom33" ENSG00000109133 "Transmembrane protein 33" P57088 4 41935129-41960803 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075863 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Mixed function" 1 "HPA075863: " "unprognostic (7.14e-2)" "unprognostic (9.25e-3)" "unprognostic (1.59e-2)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (3.94e-2)" "unprognostic (5.45e-2)" "unprognostic (2.09e-1)" "unprognostic (1.16e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.70e-2)" "unprognostic (4.20e-1)" "unprognostic (9.35e-3)" "unprognostic (2.36e-2)" TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.1;intestine: 35.6;seminal vesicle: 49.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.1;Cone photoreceptor cells: 10.2;Excitatory neurons: 14.5;Horizontal cells: 16.4;Inhibitory neurons: 23.6;Muller glia cells: 10.9;Oligodendrocyte precursor cells: 12.3;Ovarian stromal cells: 12.5;Peritubular cells: 19.9" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 13.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Smooth muscle cells - Muscle contraction" 22 Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981380-34985347 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 19.1;Fibroblasts: 12.5;Gastric mucus-secreting cells: 10.0;Mesothelial cells: 18.6;Microglial cells: 10.7;Schwann cells: 32.1;T-cells: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 97.4;liver: 97.6;parathyroid gland: 120.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Hepatocytes: 176.6;Muller glia cells: 131.8;Proximal enterocytes: 530.6;Proximal tubular cells: 173.8;Syncytiotrophoblasts: 130.7" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 32.2" "Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" TMEM38A "MGC3169, TRIC-A" ENSG00000072954 "Transmembrane protein 38A" Q9H6F2 19 16661139-16690023 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 559.8;tongue: 249.5" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 132.5;Skeletal myocytes: 259.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 36.7;eosinophil: 12.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.7" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048100, HPA050463" Enhanced Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Skeletal myocytes - Muscle contraction" Nucleoplasm "HPA048100: , HPA050463: AB_2681137" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-1)" "unprognostic (2.99e-1)" "unprognostic (3.49e-1)" "prognostic favorable (2.78e-5)" "unprognostic (2.94e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "prognostic favorable (2.99e-10)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (4.50e-3)" "unprognostic (1.96e-2)" TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 72.9;tongue: 59.7" "Cell type enhanced" "Detected in all" "Early spermatids: 257.3;Late spermatids: 501.0;Spermatocytes: 144.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Late spermatids - Spermatogenesis" 1 "HPA018465: AB_1858116" "unprognostic (3.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-2)" "unprognostic (3.11e-3)" "unprognostic (1.88e-2)" "unprognostic (3.54e-2)" "unprognostic (5.82e-3)" "unprognostic (5.80e-2)" "prognostic favorable (7.96e-4)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (3.89e-3)" "unprognostic (9.98e-2)" TMEM39A "FLJ10902, SUSR2" ENSG00000176142 "Transmembrane protein 39A" Q9NV64 3 119428949-119468830 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039140 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" Nucleoplasm Vesicles "HPA039140: AB_10673303" "unprognostic (2.16e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-2)" "unprognostic (6.86e-2)" "unprognostic (1.56e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (9.68e-2)" "unprognostic (6.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (4.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.88e-1)" "unprognostic (6.41e-2)" TMEM39B FLJ10315 ENSG00000121775 "Transmembrane protein 39B" Q9GZU3 1 32072031-32102866 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040191, HPA040224" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" Vesicles "HPA040191: AB_10805706, HPA040224: AB_10795274" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (4.38e-2)" "prognostic unfavorable (3.00e-4)" "unprognostic (1.06e-1)" "unprognostic (1.14e-2)" "prognostic unfavorable (2.82e-6)" "unprognostic (1.10e-2)" "unprognostic (3.37e-2)" "unprognostic (1.74e-1)" "unprognostic (3.63e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (5.11e-9)" "unprognostic (2.20e-1)" "unprognostic (5.80e-2)" "unprognostic (4.45e-2)" "unprognostic (2.10e-1)" TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 213.7;skin 1: 62.7;vagina: 77.7" "Group enriched" "Detected in many" 4 "Suprabasal keratinocytes: 334.8;Syncytiotrophoblasts: 802.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 63.9;head and neck cancer: 46.8" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved "Plasma membrane,Cytosol" NA NA 2500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 189.6;Squamous epithelial cells: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" TMEM41B KIAA0033 ENSG00000166471 "Transmembrane protein 41B" Q5BJD5 11 9280654-9314636 "Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Lipid transport, Neurogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014946 Uncertain Approved Peroxisomes NA NA "Cluster 24: Non-specific - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 Peroxisomes "HPA014946: AB_2205037" "unprognostic (1.21e-1)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.18e-6)" "unprognostic (6.18e-2)" "unprognostic (9.37e-3)" "unprognostic (4.90e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (8.18e-2)" TMEM42 MGC29956 ENSG00000169964 "Transmembrane protein 42" Q69YG0 3 44861904-44865670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 69.0;Late spermatids: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052569 Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 6: Ovarian stromal cells - Transcription" 41 Nucleoplasm Nucleoli "HPA052569: AB_2681871" "prognostic favorable (5.23e-4)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (3.73e-2)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (6.99e-3)" "unprognostic (1.64e-2)" "unprognostic (9.16e-2)" "unprognostic (9.23e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "prognostic favorable (1.10e-5)" "unprognostic (1.31e-2)" "unprognostic (3.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Immunity, Innate immunity" "Cardiomyopathy, Deafness, Disease variant, Emery-Dreifuss muscular dystrophy, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Fibroblasts - ECM organization" 13 "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.2;Endothelial cells: 24.2;granulocytes: 74.2;Intestinal goblet cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 3.6;NK-cell: 8.3" "Group enriched" "Detected in many" 9 "granulocytes: 3.6;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 462.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 477.4;Club cells: 521.2;Early spermatids: 273.7;Ionocytes: 610.4;Suprabasal keratinocytes: 226.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 13: Skin - Cornification" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.6;intestine: 132.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 79.7;Club cells: 79.2;Distal enterocytes: 262.3;Enteroendocrine cells: 79.6;Ionocytes: 92.4;Paneth cells: 125.7;Proximal enterocytes: 291.2;Undifferentiated cells: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 3.6;neutrophil: 11.8" "Group enriched" "Detected in many" 14 "granulocytes: 11.8;T-cells: 3.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.4;prostate cancer: 85.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 31 Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 101.8;Astrocytes: 81.1;Leydig cells: 73.6;Melanocytes: 118.5;Muller glia cells: 130.2;Peritubular cells: 91.6;Smooth muscle cells: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Nuclear membrane" "HPA046658: AB_2679742" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (5.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.67e-2)" "unprognostic (4.23e-2)" "unprognostic (1.36e-1)" "prognostic favorable (4.05e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-2)" "unprognostic (2.76e-1)" "unprognostic (9.94e-2)" TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Kidney - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 9 "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" TMEM50B C21orf4 ENSG00000142188 "Transmembrane protein 50B" P56557 21 33432485-33479974 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034199, HPA068995" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 18 "Nucleoli fibrillar center" "CAB034199: AB_2205160, HPA068995: AB_2686066" "unprognostic (3.22e-1)" "unprognostic (5.93e-2)" "unprognostic (7.82e-2)" "unprognostic (6.14e-2)" "unprognostic (1.26e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.24e-2)" "prognostic favorable (3.33e-4)" "unprognostic (8.65e-2)" "unprognostic (3.36e-2)" "unprognostic (1.85e-2)" "unprognostic (3.54e-2)" "unprognostic (9.58e-3)" "unprognostic (3.41e-3)" "unprognostic (8.28e-2)" "unprognostic (3.47e-3)" "unprognostic (3.32e-3)" TMEM51 "C1orf72, FLJ10199" ENSG00000171729 "Transmembrane protein 51" Q9NW97 1 15152532-15220478 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 84.5;Exocrine glandular cells: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014547, HPA019441" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 32 "Nucleoplasm, Cytosol" "HPA014547: AB_1858121, HPA019441: AB_2670142" "unprognostic (1.21e-1)" "unprognostic (1.84e-1)" "unprognostic (8.74e-2)" "unprognostic (1.89e-2)" "unprognostic (3.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.47e-2)" "unprognostic (7.81e-3)" "unprognostic (7.84e-2)" "unprognostic (1.39e-1)" "unprognostic (3.00e-2)" "unprognostic (8.91e-2)" "prognostic favorable (8.16e-8)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (5.58e-2)" "unprognostic (1.67e-3)" TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 209.9;skeletal muscle: 288.4;tongue: 199.5" "Cell type enriched" "Detected in many" 5 "Skeletal myocytes: 227.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "HPA079372: " "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (7.35e-3)" "unprognostic (1.04e-5)" "unprognostic (1.46e-1)" "unprognostic (6.71e-3)" "unprognostic (3.68e-2)" "unprognostic (9.49e-2)" "unprognostic (1.69e-1)" "unprognostic (3.83e-3)" "unprognostic (5.80e-2)" "unprognostic (8.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.0" "Cell type enriched" "Detected in many" 8 "Late spermatids: 1003.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.6" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" TMEM54 "BCLP, CAC-1" ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 260.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1854.5;Paneth cells: 671.1;Proximal enterocytes: 472.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 19 Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 27000 "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA075447: " "unprognostic (2.63e-1)" "unprognostic (9.88e-2)" "unprognostic (2.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (8.28e-2)" "unprognostic (4.10e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (4.49e-2)" "unprognostic (6.34e-3)" "unprognostic (9.84e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-3)" "unprognostic (7.38e-2)" TMEM59L "BSMAP, C19orf4" ENSG00000105696 "Transmembrane protein 59 like" Q9UK28 19 18607430-18621039 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 351.9" "Cell type enhanced" "Detected in some" "Astrocytes: 34.1;Bipolar cells: 82.1;Excitatory neurons: 107.0;Horizontal cells: 83.7;Inhibitory neurons: 84.3;Muller glia cells: 60.3;Oligodendrocyte precursor cells: 39.6" "Cancer enriched" "Detected in many" 8 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.9" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010661 Approved NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "HPA010661: AB_1078338" "unprognostic (3.24e-2)" "unprognostic (5.53e-2)" "unprognostic (1.24e-4)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.70e-1)" "unprognostic (5.40e-3)" "unprognostic (3.53e-2)" "unprognostic (6.91e-2)" "unprognostic (1.10e-1)" "unprognostic (1.40e-3)" "prognostic favorable (8.80e-4)" "unprognostic (4.65e-2)" "unprognostic (9.17e-7)" "unprognostic (1.47e-3)" "unprognostic (2.53e-1)" "unprognostic (1.49e-1)" "unprognostic (1.84e-5)" TMEM60 "C7orf35, DC32" ENSG00000135211 "Transmembrane protein 60" Q9H2L4 7 77793728-77798434 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 122.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062625 Approved NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Mixed function" 86 "HPA062625: AB_2684811" "prognostic favorable (3.09e-4)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-3)" "unprognostic (3.91e-2)" "unprognostic (5.28e-3)" "unprognostic (2.73e-3)" "unprognostic (3.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (2.72e-2)" "unprognostic (9.44e-2)" "unprognostic (2.07e-3)" "unprognostic (4.43e-3)" TMEM61 ENSG00000143001 "Transmembrane protein 61" Q8N0U2 1 54980628-54992288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.0;pituitary gland: 46.4;salivary gland: 19.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.5;Enteroendocrine cells: 26.0;Intestinal goblet cells: 63.6;Ionocytes: 42.3;Oocytes: 22.8;Salivary duct cells: 39.7;Serous glandular cells: 22.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.4;pancreatic cancer: 3.6" "Adipose subcutaneous - Smooth muscle cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA030614 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 11 "HPA030614: AB_10603216" "unprognostic (7.62e-2)" "unprognostic (1.67e-3)" "prognostic favorable (1.07e-4)" "unprognostic (1.00e-1)" "unprognostic (6.63e-4)" "unprognostic (6.15e-2)" "unprognostic (2.67e-3)" "unprognostic (1.49e-1)" "unprognostic (3.05e-1)" "unprognostic (4.46e-2)" "unprognostic (1.91e-2)" "unprognostic (7.24e-2)" "prognostic favorable (1.78e-7)" "unprognostic (8.47e-2)" "unprognostic (2.20e-2)" "unprognostic (4.01e-2)" "unprognostic (4.62e-3)" TMEM62 FLJ23375 ENSG00000137842 "Transmembrane protein 62" Q0P6H9 15 43123279-43185144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044461, HPA062359" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 73: B-cells - B-cell function" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies, Cytoplasmic bodies" "HPA044461: AB_2678950, HPA062359: AB_2684747" "unprognostic (7.43e-2)" "unprognostic (4.96e-2)" "unprognostic (4.56e-2)" "prognostic favorable (9.72e-7)" "unprognostic (2.53e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.41e-2)" "unprognostic (4.83e-2)" "unprognostic (3.30e-1)" "unprognostic (3.90e-2)" "unprognostic (1.77e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (6.48e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" TMEM63A KIAA0792 ENSG00000196187 "Transmembrane protein 63A" O94886 1 225845536-225882380 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 157.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 300.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066504, HPA066936, HPA068918" Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Vesicles, Centriolar satellite" "HPA066504: AB_2685680, HPA066936: AB_2685751, HPA068918: AB_2686057" "unprognostic (5.31e-2)" "unprognostic (3.46e-2)" "unprognostic (2.14e-2)" "prognostic favorable (8.79e-4)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.92e-2)" TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.6;Late spermatids: 107.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 21: Testis - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 54.9;pituitary gland: 40.8" "Cell type enhanced" "Detected in many" "Early spermatids: 10.8;Enteroendocrine cells: 17.5;Excitatory neurons: 25.0;Inhibitory neurons: 21.2;Oligodendrocyte precursor cells: 15.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 14.8" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "epididymis: 141.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 49.8;Leydig cells: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "CAB034221: AB_1567653" "unprognostic (3.61e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (2.55e-3)" "unprognostic (4.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (3.30e-1)" "unprognostic (2.35e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" TMEM65 ENSG00000164983 "Transmembrane protein 65" Q6PI78 8 124306189-124372701 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.3;Inhibitory neurons: 134.1;Microglial cells: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025020 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 29 "HPA025020: AB_2205178" "prognostic unfavorable (2.17e-4)" "unprognostic (3.52e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.24e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (2.26e-2)" "unprognostic (1.84e-1)" "unprognostic (4.71e-2)" "unprognostic (7.95e-2)" "unprognostic (8.26e-2)" "unprognostic (5.67e-2)" "unprognostic (8.25e-2)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (3.78e-1)" TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" Vesicles "HPA018216: AB_2205185, HPA019173: AB_1858129" "unprognostic (4.43e-2)" "unprognostic (3.10e-2)" "unprognostic (8.04e-2)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (1.63e-1)" TMEM69 "C1orf154, FLJ21029" ENSG00000159596 "Transmembrane protein 69" Q5SWH9 1 45688181-45694436 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026993 Approved Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 2 Nucleoplasm "HPA026993: AB_10601824" "prognostic favorable (2.24e-4)" "unprognostic (2.47e-1)" "unprognostic (5.25e-2)" "unprognostic (1.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.66e-8)" "unprognostic (4.05e-2)" "unprognostic (1.59e-3)" "unprognostic (5.17e-2)" "unprognostic (3.98e-3)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (1.49e-2)" "unprognostic (1.96e-1)" "unprognostic (4.41e-3)" "unprognostic (3.65e-2)" TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 97.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;heart muscle: 35.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.6;Kupffer cells: 19.6;Langerhans cells: 34.1;Macrophages: 23.1;NK-cells: 65.6;Schwann cells: 21.3;T-cells: 36.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 20.8" "Immune cell enhanced" "Detected in all" "neutrophil: 270.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 270.6" "Cancer enhanced" "Detected in many" "Bone cancer: 9.1;Leukemia: 8.0" "Colon - Enteric glia cells, Kidney - T-cells, Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" TMEM72 "bA285G1.3, C10orf127, KSP37" ENSG00000187783 "Transmembrane protein 72" A0PK05 10 44911316-44937010 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 46.6;kidney: 72.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 25.3;Distal enterocytes: 31.0;Distal tubular cells: 24.6;Enteroendocrine cells: 6.5;Late spermatids: 16.3;Paneth cells: 11.4" "Cancer enriched" "Detected in some" 8 "renal cancer: 8.7" "Region enriched" "Detected in all" 13 "choroid plexus: 112.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Myeloma: 3.7" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039894, HPA062907" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" 9 "HPA039894: AB_10795261, HPA062907: AB_2684900" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (8.58e-2)" "unprognostic (5.45e-2)" "prognostic favorable (1.01e-4)" "unprognostic (4.99e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" TMEM74 "FLJ30668, NET36" ENSG00000164841 "Transmembrane protein 74" Q96NL1 8 108606850-108787594 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;retina: 2.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.0;Cone photoreceptor cells: 8.5;Oocytes: 11.0;Rod photoreceptor cells: 9.8;Schwann cells: 17.4;Spermatogonia: 7.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015672, HPA076461" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 55: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 5 "Golgi apparatus, Cytosol" "HPA015672: AB_1858132, HPA076461: " "unprognostic (8.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.25e-2)" "unprognostic (6.33e-2)" "unprognostic (2.05e-1)" "unprognostic (4.18e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-2)" "unprognostic (3.97e-2)" "unprognostic (3.75e-4)" "unprognostic (8.77e-2)" "unprognostic (6.36e-2)" "unprognostic (5.95e-2)" "unprognostic (1.46e-3)" TMEM74B "C20orf46, FLJ11190" ENSG00000125895 "Transmembrane protein 74B" Q9NUR3 20 1180561-1185415 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;lung: 26.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.6;Enteroendocrine cells: 15.0;Horizontal cells: 23.9;Inhibitory neurons: 15.6;Intestinal goblet cells: 20.5;Paneth cells: 16.5;Proximal enterocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045213 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Golgi apparatus" "HPA045213: AB_10961999" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (5.73e-2)" "unprognostic (1.03e-2)" "unprognostic (6.91e-3)" "unprognostic (1.97e-1)" "unprognostic (1.77e-4)" "unprognostic (9.58e-2)" "prognostic favorable (3.07e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.55e-7)" "unprognostic (1.20e-1)" "unprognostic (9.77e-2)" "unprognostic (8.37e-2)" "unprognostic (5.07e-3)" TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.7;skin 1: 87.1;vagina: 57.6" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.8;Squamous epithelial cells: 66.7;Suprabasal keratinocytes: 161.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 31 "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" TMEM80 FLJ38216 ENSG00000177042 "Transmembrane protein 80" Q96HE8 11 695591-705028 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059592, HPA067046" Uncertain Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 53 "Golgi apparatus" "HPA059592: AB_2684076, HPA067046: AB_2685769" "unprognostic (1.48e-1)" "unprognostic (6.55e-3)" "unprognostic (1.70e-2)" "unprognostic (2.64e-2)" "unprognostic (2.71e-3)" "unprognostic (1.68e-3)" "unprognostic (4.36e-2)" "unprognostic (5.39e-3)" "unprognostic (3.85e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-3)" "unprognostic (1.03e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (3.27e-1)" "unprognostic (4.23e-3)" TMEM81 "HC3107, KVLA2788, MGC75217, UNQ2788" ENSG00000174529 "Transmembrane protein 81" Q6P7N7 1 205083129-205084460 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 15.2" "Cell type enriched" "Detected in some" 7 "Early spermatids: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052515 Approved "Intermediate filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 18: Early spermatids - Unknown function" "Intermediate filaments" "HPA052515: AB_2681858" "unprognostic (9.19e-3)" "unprognostic (3.53e-1)" "unprognostic (1.91e-3)" "unprognostic (6.48e-2)" "unprognostic (2.44e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (3.66e-2)" "unprognostic (2.68e-2)" "unprognostic (6.18e-2)" "unprognostic (5.86e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (8.91e-2)" "unprognostic (6.24e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.67e-4)" TMEM82 ENSG00000162460 "Transmembrane protein 82" A0PJX8 1 15742499-15747982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.7;kidney: 11.2;liver: 51.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 68.8;Hepatocytes: 44.8;Paneth cells: 49.0;Proximal enterocytes: 183.5;Proximal tubular cells: 42.9" "Cancer enhanced" "Detected in some" "liver cancer: 10.2;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA060282 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA060282: AB_2684241" "unprognostic (2.46e-2)" "unprognostic (7.96e-2)" "unprognostic (4.88e-2)" "unprognostic (1.40e-2)" "unprognostic (6.45e-2)" "unprognostic (6.90e-2)" "unprognostic (4.80e-2)" "prognostic favorable (3.80e-7)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (4.75e-2)" "unprognostic (1.09e-1)" TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.1" "Cell type enhanced" "Detected in many" "Early spermatids: 15.8;Hofbauer cells: 35.9;Late spermatids: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 11.4" "Breast - Breast glandular cells, Lung - Macrophages, Pancreas - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 38 "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226638-55228784 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 10.7;liver: 16.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 40.1;Erythroid cells: 42.4;Hepatocytes: 28.6" "Cancer enriched" "Detected in all" 5 "liver cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA057689 Uncertain Uncertain Midbody,Centrosome Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Erythroid cells - Oxygen transport" 92 Centrosome Midbody "HPA057689: AB_2683504" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.76e-5)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (3.13e-4)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "prognostic favorable (9.97e-6)" "unprognostic (1.96e-2)" "unprognostic (6.63e-8)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (3.70e-1)" "unprognostic (3.19e-3)" TMEM87A DKFZP564G2022 ENSG00000103978 "Transmembrane protein 87A" Q8NBN3 15 42210447-42273534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018104, HPA018189" Enhanced Supported "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Alveolar cells - Lung function" "Golgi apparatus" "HPA018104: AB_1858135, HPA018189: AB_2205198" "unprognostic (7.07e-2)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (2.49e-1)" "unprognostic (6.39e-3)" "unprognostic (1.19e-2)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (8.13e-3)" "unprognostic (4.31e-3)" "unprognostic (1.38e-1)" "unprognostic (3.41e-2)" "unprognostic (7.90e-2)" "unprognostic (2.19e-1)" "unprognostic (5.49e-3)" "unprognostic (3.63e-1)" TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" TMEM88 "FLJ20025, MGC71744" ENSG00000167874 "Transmembrane protein 88" Q6PEY1 17 7855066-7856099 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 95.5" "Group enriched" "Detected in many" 5 "Adipocytes: 173.7;Endothelial cells: 144.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 60.0" "Colon - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052991 Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 10 "HPA052991: AB_2682006" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (3.44e-2)" "unprognostic (3.03e-1)" "unprognostic (6.49e-2)" "prognostic favorable (4.43e-6)" "unprognostic (1.98e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-3)" "unprognostic (9.04e-2)" "unprognostic (1.09e-2)" "unprognostic (2.68e-3)" "unprognostic (1.71e-1)" "unprognostic (7.56e-2)" "unprognostic (2.72e-1)" TMEM88B ENSG00000205116 "Transmembrane protein 88B" A6NKF7 1 1425871-1430255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 77.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065743 Enhanced NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "HPA065743: AB_2685552" "unprognostic (3.17e-2)" "unprognostic (1.42e-2)" "unprognostic (1.63e-4)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "unprognostic (2.67e-1)" "unprognostic (2.91e-2)" "unprognostic (5.30e-5)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (3.53e-2)" "unprognostic (7.19e-2)" "unprognostic (1.45e-1)" "unprognostic (7.95e-2)" TMEM89 ENSG00000183396 "Transmembrane protein 89" A2RUT3 3 48620759-48621769 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 24.1" "Group enriched" "Detected in some" 22 "Early spermatids: 407.4;Late spermatids: 206.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053577 Uncertain NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Early spermatids - Unknown function" "HPA053577: AB_2682196" "unprognostic (1.61e-1)" "unprognostic (2.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.94e-3)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (2.02e-2)" "unprognostic (6.31e-3)" "unprognostic (5.90e-3)" "unprognostic (3.35e-2)" "unprognostic (3.83e-2)" "unprognostic (8.41e-2)" "unprognostic (2.71e-1)" "unprognostic (3.86e-2)" TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.3" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles "HPA052130: AB_2681740, HPA062701: AB_2684839" "unprognostic (5.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.96e-1)" "unprognostic (3.53e-2)" "unprognostic (3.81e-1)" "unprognostic (1.42e-1)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (2.97e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.14e-4)" "unprognostic (5.93e-2)" "prognostic favorable (1.89e-15)" "unprognostic (8.00e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 6: Ovarian stromal cells - Transcription" 11 Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.88e-1)" "prognostic unfavorable (6.57e-4)" "unprognostic (2.95e-1)" "unprognostic (3.67e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (2.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.88e-2)" "unprognostic (2.38e-1)" "unprognostic (9.17e-2)" "unprognostic (3.32e-1)" "unprognostic (9.90e-2)" TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.0" "Cell type enhanced" "Detected in many" "Early spermatids: 171.2;Extravillous trophoblasts: 104.1;Late spermatids: 473.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 194.5" "Group enriched" "Detected in all" 8 "granulocytes: 194.5;monocytes: 52.0" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 57: Platelets - Hemostasis" "HPA053240: AB_2682085" "unprognostic (3.02e-3)" "unprognostic (1.92e-2)" "unprognostic (5.13e-3)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.69e-3)" "prognostic favorable (3.54e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.06e-2)" TMEM92 FLJ33318 ENSG00000167105 "Transmembrane protein 92" Q6UXU6 17 50271406-50281485 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.5;stomach 1: 22.3" "Cell type enriched" "Detected in many" 9 "Proximal enterocytes: 281.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.8" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063009, HPA069820" Approved Uncertain Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 2 Nucleoplasm "HPA063009: AB_2684921, HPA069820: AB_2686208" "unprognostic (3.54e-3)" "unprognostic (2.39e-2)" "unprognostic (9.85e-2)" "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.37e-3)" "unprognostic (2.45e-2)" "unprognostic (1.11e-1)" "unprognostic (4.39e-1)" "unprognostic (3.88e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (1.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (7.81e-2)" TMEM94 KIAA0195 ENSG00000177728 "Transmembrane protein 94" Q12767 17 75441159-75500452 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008423, HPA050660" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Astrocytes - Unknown function" Nucleoplasm "Nuclear bodies" "HPA008423: AB_1852283, HPA050660: AB_2681207" "unprognostic (4.05e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (7.27e-2)" "prognostic favorable (2.26e-4)" "unprognostic (9.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.44e-2)" "unprognostic (4.96e-2)" TMEM97 "σ2R, MAC30" ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.8;pancreas: 311.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 133.1;Cholangiocytes: 125.9;Exocrine glandular cells: 122.6;Granulosa cells: 116.1;Hepatocytes: 202.9;Oocytes: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 15: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 49 "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 404.0" "Cell type enhanced" "Detected in many" "Mesothelial cells: 197.7;Ovarian stromal cells: 241.9;Proximal enterocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 12 "dendritic cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 6 Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" TMEM9B C11orf15 ENSG00000175348 "TMEM9 domain family member B" Q9NQ34 11 8947202-8965011 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037784 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA037784: AB_10671886" "unprognostic (3.18e-1)" "unprognostic (4.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.84e-3)" "unprognostic (1.13e-1)" "unprognostic (8.48e-3)" "unprognostic (2.56e-2)" "unprognostic (6.34e-2)" "unprognostic (1.52e-1)" "unprognostic (3.78e-2)" "unprognostic (1.89e-2)" "unprognostic (5.06e-1)" "prognostic favorable (4.26e-5)" "unprognostic (1.83e-1)" "unprognostic (1.82e-1)" "unprognostic (5.51e-3)" "unprognostic (9.56e-2)" TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4;pituitary gland: 9.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Horizontal cells: 3.1;Skeletal myocytes: 2.9;Spermatocytes: 3.2;Spermatogonia: 3.1" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Breast - T-cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 136.6" "Group enriched" "Detected in some" 38 "Distal enterocytes: 186.1;Proximal enterocytes: 460.0" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gastric cancer: 1.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Supported Mitochondria,Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Mitochondria, Cytosol" "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" TMIGD2 "CD28H, IGPR-1, MGC23244" ENSG00000167664 "Transmembrane and immunoglobulin domain containing 2" Q96BF3 19 4292227-4302431 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 34.0" "Group enriched" "Detected in some" 4 "dendritic cells: 45.0;NK-cells: 75.3;T-cells: 56.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 113.6" "Group enriched" "Detected in many" 38 "dendritic cells: 108.6;NK-cells: 89.3;T-cells: 113.6" "Group enriched" "Detected in some" 8 "Leukemia: 11.7;Neuroblastoma: 3.9" "Adipose visceral - T-cells, Liver - NK-cells (Liver)" "Low region specificity" "Detected in some" HPA011081 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 71: Thymus - Adaptive immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA011081: AB_1079372" "unprognostic (1.08e-3)" "unprognostic (6.55e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-4)" "unprognostic (4.31e-2)" "unprognostic (8.68e-3)" "unprognostic (7.78e-3)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.28e-1)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" "unprognostic (7.10e-5)" "unprognostic (2.62e-2)" "unprognostic (4.54e-1)" "unprognostic (5.12e-4)" "unprognostic (8.89e-4)" TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.2" "Cell type enhanced" "Detected in all" "monocytes: 275.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 190000 "Cluster 33: Non-specific - ATP binding" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 6 "Nuclear membrane" "CAB009847: AB_2205450, HPA008150: AB_1079235, HPA070805: " "unprognostic (2.36e-1)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-3)" "prognostic unfavorable (9.34e-4)" "unprognostic (6.01e-3)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (3.26e-2)" TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.1;Rod photoreceptor cells: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 49: Non-specific - Transcription" 30 "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 83.3;lymphoid tissue: 27.7;vagina: 40.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.8;Basal squamous epithelial cells: 8.0;Serous glandular cells: 17.7;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 30.0" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA078316: " "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 84 "cervix: 50.1;esophagus: 69.8;lymphoid tissue: 33.5;salivary gland: 20.4;vagina: 73.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 58.9;Basal respiratory cells: 23.9;Serous glandular cells: 48.6;Suprabasal keratinocytes: 124.2" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.1;head and neck cancer: 1.6;lymphoma: 2.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "HPA077704: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 87.1;esophagus: 214.0;salivary gland: 55.0;vagina: 151.5" "Group enriched" "Detected in some" 6 "Ionocytes: 73.3;Salivary duct cells: 82.9;Suprabasal keratinocytes: 67.4" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 8.2" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Enhanced Approved "Golgi apparatus" "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA043816: , HPA051062: AB_2681329" "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.7;skin 1: 9.0;vagina: 4.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Cytotrophoblasts: 1.6;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 8.6" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;Leukemia: 1.0;lymphoma: 1.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.3;skin 1: 39.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 22.7;Glandular and luminal cells: 11.6;Salivary duct cells: 13.9;Suprabasal keratinocytes: 21.3;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA079555 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Plasma membrane" "HPA079555: " "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 271.1;stomach 1: 142.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Gastric mucus-secreting cells: 171.0;Paneth cells: 147.3;Prostatic glandular cells: 371.1;Proximal enterocytes: 168.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 267.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TMPRSS4 "CAP2, MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 105.7;intestine: 42.1;urinary bladder: 71.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 99.4;Basal squamous epithelial cells: 61.8;Club cells: 111.2;Distal enterocytes: 143.5;Glandular and luminal cells: 64.6;Ionocytes: 135.5;Squamous epithelial cells: 126.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 10 "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;salivary gland: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 25.1;Mucus glandular cells: 15.2;Oligodendrocytes: 14.4;Schwann cells: 17.2;Serous glandular cells: 14.1" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.4" "Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" TMPRSS7 ENSG00000176040 "Transmembrane serine protease 7" Q7RTY8 3 112034736-112081269 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.6;Early spermatids: 8.3;Excitatory neurons: 3.9;Intestinal goblet cells: 2.1;Proximal enterocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" HPA040630 Uncertain NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" "HPA040630: AB_10796124" "unprognostic (4.02e-2)" "unprognostic (9.87e-2)" "unprognostic (9.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.24e-1)" "unprognostic (4.64e-3)" "unprognostic (6.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.94e-1)" "unprognostic (7.23e-2)" "unprognostic (2.96e-1)" "unprognostic (2.06e-2)" TMPRSS9 ENSG00000178297 "Transmembrane serine protease 9" Q7Z410 19 2360238-2426261 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 4.0;lymphoid tissue: 2.3;testis: 3.6" "Cell type enhanced" "Detected in some" "Early spermatids: 22.3;Erythroid cells: 20.3;Granulosa cells: 8.0;Late spermatids: 57.5;Sertoli cells: 10.9;Spermatocytes: 8.3" "Cancer enhanced" "Detected in some" "liver cancer: 1.5;melanoma: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051483 Uncertain NA NA "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" "HPA051483: AB_2681501" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (5.62e-3)" "unprognostic (1.86e-1)" "unprognostic (1.54e-2)" "unprognostic (1.87e-3)" "unprognostic (3.30e-1)" "unprognostic (6.44e-2)" "unprognostic (7.29e-2)" "unprognostic (2.07e-1)" "unprognostic (6.30e-2)" "unprognostic (9.20e-3)" "unprognostic (2.28e-3)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (3.07e-3)" "unprognostic (6.73e-2)" TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.0;Astrocytes: 61.3;Endothelial cells: 84.6;Excitatory neurons: 180.1;Inhibitory neurons: 191.9;Skeletal myocytes: 59.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 2003.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 27.8" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "Actin filaments" "HPA026954: AB_2256025, HPA026955: AB_10602282" "unprognostic (1.56e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" "unprognostic (7.38e-2)" "unprognostic (2.60e-2)" "unprognostic (3.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.16e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-2)" "prognostic favorable (2.84e-5)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.06e-2)" "unprognostic (8.06e-2)" TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 31: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" TMTC4 "FLJ14624, FLJ22153" ENSG00000125247 "Transmembrane O-mannosyltransferase targeting cadherins 4" Q5T4D3 13 100603625-100675093 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016489, HPA057056" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" Vesicles "HPA016489: AB_1858157, HPA057056: " "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (8.34e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.99e-1)" "unprognostic (6.04e-2)" "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 188.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 7 Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" TMUB2 MGC3123 ENSG00000168591 "Transmembrane and ubiquitin like domain containing 2" Q71RG4 17 44186970-44191929 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043137 Approved Approved Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 74: Neutrophils - Degranulation" 15 "Vesicles, Cytosol" "HPA043137: AB_10794388" "unprognostic (4.57e-2)" "unprognostic (1.58e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-2)" "unprognostic (6.37e-2)" "unprognostic (1.85e-2)" "unprognostic (6.43e-3)" "unprognostic (1.07e-1)" "unprognostic (2.05e-1)" "unprognostic (3.35e-2)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "unprognostic (2.78e-3)" TMX1 "PDIA11, TMX, TXNDC, TXNDC1" ENSG00000139921 "Thioredoxin related transmembrane protein 1" Q9H3N1 14 51240162-51257655 "Predicted membrane proteins, Transporters" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003085 Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 26000 "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Liver - Plasma proteins" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 4: Extravillous trophoblasts - Unknown function" 10 "Endoplasmic reticulum" Nucleoli "HPA003085: AB_1080424" "unprognostic (1.83e-1)" "unprognostic (7.42e-2)" "unprognostic (6.97e-3)" "unprognostic (1.49e-2)" "unprognostic (2.63e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.29e-6)" "unprognostic (3.70e-2)" "unprognostic (1.51e-1)" "unprognostic (6.84e-2)" "unprognostic (2.44e-3)" "unprognostic (5.07e-2)" "unprognostic (9.30e-2)" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.18e-1)" "unprognostic (3.21e-3)" TMX2 "PDIA12, TXNDC14" ENSG00000213593 "Thioredoxin related transmembrane protein 2" Q9Y320 11 57712593-57740973 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040282, HPA063763" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 131 "Nucleoplasm, Cytosol" "HPA040282: AB_10697715, HPA063763: AB_2685116" "unprognostic (3.66e-3)" "unprognostic (6.96e-2)" "unprognostic (6.69e-3)" "unprognostic (2.73e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (4.11e-4)" "unprognostic (4.48e-2)" "unprognostic (2.98e-1)" "unprognostic (7.26e-3)" "unprognostic (1.90e-2)" "unprognostic (2.22e-1)" "prognostic favorable (1.55e-5)" "unprognostic (5.88e-3)" "unprognostic (4.19e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (3.37e-4)" TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" Enzyme NA NA 36000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" TMX4 "DJ971N18.2, KIAA1162, PDIA14, TXNDC13" ENSG00000125827 "Thioredoxin related transmembrane protein 4" Q9H1E5 20 7977346-8019805 "Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.7;Early spermatids: 584.4;Late spermatids: 1564.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000399, HPA015752" Enhanced Approved "Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Late spermatids - Spermatogenesis" "Nuclear membrane" "HPA000399: AB_1858471, HPA015752: AB_1858470" "unprognostic (3.93e-2)" "unprognostic (5.96e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-3)" "unprognostic (5.14e-2)" "unprognostic (8.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" "unprognostic (3.66e-1)" "unprognostic (2.96e-1)" "unprognostic (5.80e-3)" "unprognostic (3.16e-1)" "prognostic favorable (2.60e-5)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (7.06e-2)" TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" HPA054475 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" TNFRSF10B "CD262, DR5, KILLER, TRAIL-R2, TRAILR2, TRICK2A, TRICKB" ENSG00000120889 "TNF receptor superfamily member 10b" O14763 8 23020133-23069031 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" HPA023625 Approved NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 2 "HPA023625: AB_1847860" "unprognostic (8.43e-3)" "unprognostic (7.43e-3)" "unprognostic (3.04e-2)" "unprognostic (4.94e-3)" "unprognostic (1.13e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (9.51e-3)" "unprognostic (2.70e-1)" "unprognostic (2.82e-2)" "unprognostic (2.30e-3)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (4.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.8;lymphoid tissue: 23.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 2.8;Ionocytes: 3.7;Proximal enterocytes: 4.6;Secretory cells: 3.6;Serous glandular cells: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3204.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3204.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Testis - Sertoli cells" CAB025635 Enhanced NA NA 14600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 74: Neutrophils - Degranulation" 23 "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.7;Endothelial cells: 51.5;Gastric mucus-secreting cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 19 "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" TNFRSF11A "CD265, FEO, LOH18CR1, ODFR, PDB2, RANK, TRANCE-R" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.4;salivary gland: 24.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 32.3;Enteroendocrine cells: 21.9;Lymphatic endothelial cells: 27.9;Paneth cells: 39.1;Proximal enterocytes: 23.4;Serous glandular cells: 36.3;Undifferentiated cells: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 2.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 2.3" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.7" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 110000 "Cluster 15: NK-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 574.8;Basal respiratory cells: 577.5;Ductal cells: 809.1;Exocrine glandular cells: 535.5;Pancreatic endocrine cells: 706.4;Secretory cells: 888.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 140.0;neutrophil: 103.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 140.0" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" HPA007853 Approved Supported "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane" Cytosol "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" TNFRSF13B "CD267, IGAD2, TACI" ENSG00000240505 "TNF receptor superfamily member 13B" O14836 17 16929816-16972118 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.4;lymphoid tissue: 32.2;skeletal muscle: 60.5" "Group enriched" "Detected in some" 39 "B-cells: 121.3;Plasma cells: 153.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 41 "memory B-cell: 131.4;naive B-cell: 52.1" "Lineage enriched" "Detected in many" 59 "B-cells: 131.4" "Group enriched" "Detected in some" 6 "lymphoma: 69.1;Myeloma: 110.9" "Adipose subcutaneous - Plasma cells, Breast - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030453 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 3 "HPA030453: AB_10601700" "unprognostic (3.94e-5)" "unprognostic (1.11e-3)" "unprognostic (4.88e-2)" "unprognostic (4.30e-3)" "unprognostic (1.23e-4)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-4)" "unprognostic (2.22e-1)" "unprognostic (9.78e-2)" "unprognostic (1.59e-5)" "unprognostic (1.20e-1)" "unprognostic (4.49e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" TNFRSF13C "BAFFR, CD268" ENSG00000159958 "TNF receptor superfamily member 13C" Q96RJ3 22 41922032-41926806 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 32.9;lymphoid tissue: 56.7" "Cell type enriched" "Detected in some" 12 "B-cells: 232.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "memory B-cell: 22.3;naive B-cell: 28.8" "Lineage enriched" "Detected in single" 44 "B-cells: 28.8" "Group enriched" "Detected in many" 5 "Leukemia: 10.0;lymphoma: 25.8" "Heart muscle - Cardiomyocytes, Lung - B-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA003246, CAB008380" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "CAB008380: AB_590602, HPA003246: AB_1078264" "unprognostic (3.43e-4)" "prognostic favorable (4.44e-7)" "unprognostic (6.52e-2)" "unprognostic (9.10e-2)" "unprognostic (7.64e-3)" "unprognostic (4.83e-3)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (2.51e-2)" "unprognostic (1.66e-1)" "unprognostic (4.79e-8)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (1.77e-1)" "unprognostic (9.44e-2)" TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 170.8;Proximal enterocytes: 210.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 17.5" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 4 "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 37.5" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 104.9;granulocytes: 35.5;Langerhans cells: 77.5;NK-cells: 77.0;Plasma cells: 92.5;Suprabasal keratinocytes: 76.6;T-cells: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.9;T-reg: 72.0" "Group enriched" "Detected in many" 11 "NK-cells: 184.9;T-cells: 72.0" "Cancer enhanced" "Detected in many" "lymphoma: 36.8;Myeloma: 25.5" "Skin - Keratinocyte (other), Stomach - Plasma cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "basal ganglia: 1.2" HPA008025 Approved "Secreted to blood" Receptor NA NA "Cluster 1: T-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 53.8;skin 1: 104.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.8;Ciliated cells: 32.7;Microglial cells: 68.0;Prostatic glandular cells: 49.4;Serous glandular cells: 33.8;Suprabasal keratinocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 54.7;skin cancer: 48.0" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved "Nucleoplasm,Golgi apparatus" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 13: Skin - Cornification" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "Golgi apparatus" Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 454.7" "Group enriched" "Detected in many" 4 "dendritic cells: 116.0;granulocytes: 454.7;monocytes: 152.3" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" Receptor NA NA 17700 570000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 66.5" "Cell type enhanced" "Detected in many" "dendritic cells: 328.8;Kupffer cells: 240.4;Langerhans cells: 352.6;Macrophages: 265.8;monocytes: 743.2;NK-cells: 332.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.3" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" Receptor NA NA 3230000 8100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 3 "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.7;urinary bladder: 142.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 129.4;dendritic cells: 182.3;Syncytiotrophoblasts: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.3" "Lineage enriched" "Detected in single" 302 "dendritic cells: 69.3" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.2;lymphoid tissue: 42.9;pituitary gland: 29.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 30.7;Excitatory neurons: 36.3;T-cells: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Low cancer specificity" "Detected in many" "Breast - T-cells, Skeletal muscle - Fibroblasts" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Low region specificity" "Detected in many" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" Receptor NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 24: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" TNFRSF4 "ACT35, CD134, OX40, TXGP1L" ENSG00000186827 "TNF receptor superfamily member 4" P43489 1 1211326-1214153 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10.0;lymphoid tissue: 13.0" "Cell type enhanced" "Detected in many" "Adipocytes: 100.7;Endothelial cells: 31.3;granulocytes: 70.3;Langerhans cells: 148.9;Lymphatic endothelial cells: 34.0;NK-cells: 29.8;Plasma cells: 51.6;T-cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 25.6;T-reg: 31.0" "Lineage enriched" "Detected in many" 6 "T-cells: 31.0" "Group enriched" "Detected in some" 17 "Leukemia: 3.4;lymphoma: 10.7;thyroid cancer: 10.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" CAB016128 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 47: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "CAB016128: AB_626897" "unprognostic (2.24e-1)" "unprognostic (8.69e-3)" "unprognostic (1.36e-1)" "unprognostic (8.55e-3)" "unprognostic (1.02e-1)" "prognostic favorable (3.50e-6)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.30e-1)" "unprognostic (1.48e-2)" "unprognostic (7.04e-3)" "unprognostic (1.04e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.52e-6)" "unprognostic (1.61e-1)" "unprognostic (5.46e-2)" "unprognostic (2.42e-1)" "unprognostic (5.91e-2)" TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.1" "Cell type enhanced" "Detected in some" "Adipocytes: 7.6;Kupffer cells: 4.8;Late spermatids: 10.1;Macrophages: 5.1;Mesothelial cells: 4.8;monocytes: 19.3" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Group enriched" "Detected in some" 4 "basal ganglia: 4.8;thalamus: 1.5" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 97.0" "Lineage enriched" "Detected in many" 5 "monocytes: 97.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 49.3" "Breast - Endothelial cells, Colon - Endothelial cells" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "Low region specificity" "Detected in all" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.6" "Cell type enhanced" "Detected in some" "granulocytes: 63.6;Langerhans cells: 36.9;NK-cells: 13.4;T-cells: 25.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 8.6;NK-cell: 5.1;T-reg: 18.6" "Group enriched" "Detected in many" 5 "granulocytes: 8.6;NK-cells: 5.1;T-cells: 18.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Plasma membrane" Nucleoli "HPA071425: AB_2686394" "unprognostic (7.23e-2)" "unprognostic (1.72e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-4)" "unprognostic (9.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.69e-8)" "unprognostic (1.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (9.55e-2)" TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 385.4;Ductal cells: 709.4;Proximal tubular cells: 567.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 266.3;classical monocyte: 133.5;intermediate monocyte: 203.5;neutrophil: 257.9;non-classical monocyte: 214.1" "Group enriched" "Detected in all" 5 "granulocytes: 266.3;monocytes: 214.1" "Group enriched" "Detected in many" 4 "head and neck cancer: 121.7;Kidney cancer: 166.1" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" Cytokine NA NA 67400 18000 "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "HPA054938: AB_2682643" "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 4.0;lymphoid tissue: 12.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.1;Ductal cells: 5.6;Early spermatids: 8.4;Late spermatids: 14.2;NK-cells: 3.9;Pancreatic endocrine cells: 3.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 8 "NK-cell: 9.9" "Lineage enriched" "Detected in many" 8 "NK-cells: 9.9" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.5;thyroid cancer: 1.7" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009193, HPA045142" Enhanced "Secreted to blood" Cytokine NA NA 17200 "Cluster 15: NK-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 17: Breast glandular cells - Lactation" 4 "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 25.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 167.6;Kupffer cells: 106.6;Langerhans cells: 300.8;Macrophages: 143.4;monocytes: 542.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 509.3" "Group enriched" "Detected in all" 11 "dendritic cells: 207.0;granulocytes: 509.3;monocytes: 352.4" "Cancer enriched" "Detected in some" 10 "Leukemia: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" Cytokine NA NA 393000 790000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 28.0;liver: 105.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 22.2;Mesothelial cells: 45.1;NK-cells: 44.3;T-cells: 56.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 199.9" "Group enriched" "Detected in all" 4 "granulocytes: 199.9;T-cells: 61.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;lymphoma: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012700 Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 41000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 19 Vesicles "HPA012700: AB_1852870" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (3.82e-4)" "unprognostic (4.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (9.23e-2)" "unprognostic (9.22e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (6.07e-13)" "unprognostic (1.09e-1)" "unprognostic (9.56e-3)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" TNMD "BRICD4, ChM1L, myodulin, TEM, tendin" ENSG00000000005 Tenomodulin Q9H2S6 X 100584936-100599885 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 20.4;breast: 12.5;seminal vesicle: 25.2" "Cell type enriched" "Detected in some" 6 "Adipocytes: 72.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "testis cancer: 1.1;Uterine cancer: 1.3" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034961, HPA055634" Uncertain NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA034961: AB_10670285, HPA055634: AB_2682868" "unprognostic (3.60e-2)" "unprognostic (9.84e-3)" "unprognostic (3.19e-2)" "unprognostic (7.77e-3)" "unprognostic (2.42e-1)" "unprognostic (2.15e-1)" "unprognostic (2.36e-2)" "unprognostic (1.37e-1)" "unprognostic (9.40e-2)" "unprognostic (9.60e-4)" "unprognostic (6.82e-2)" "unprognostic (5.67e-2)" "unprognostic (1.48e-1)" TOMM20 "KIAA0016, MAS20, MOM19, TOM20" ENSG00000173726 "Translocase of outer mitochondrial membrane 20" Q15388 1 235109341-235128837 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005585, HPA011562" Supported Enhanced Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Ribosome" Mitochondria "CAB005585: AB_628381, HPA011562: AB_1080326" "unprognostic (1.30e-1)" "unprognostic (3.08e-3)" "unprognostic (1.66e-2)" "unprognostic (4.49e-2)" "unprognostic (8.65e-3)" "unprognostic (1.17e-2)" "unprognostic (7.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.16e-3)" "unprognostic (5.05e-2)" "unprognostic (7.08e-3)" "unprognostic (2.33e-2)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (3.97e-1)" TOMM20L UNQ9438 ENSG00000196860 "Translocase of outer mitochondrial membrane 20 like" Q6UXN7 14 58395928-58408702 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 10.6" "Cell type enriched" "Detected in some" 7 "Early spermatids: 207.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076397 Enhanced NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 18: Early spermatids - Unknown function" 4 "HPA076397: " "unprognostic (1.72e-1)" "unprognostic (2.34e-4)" "unprognostic (8.13e-2)" "unprognostic (7.80e-3)" "unprognostic (5.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (4.93e-1)" "unprognostic (1.37e-3)" "unprognostic (3.06e-2)" "unprognostic (5.66e-3)" "unprognostic (4.57e-6)" "unprognostic (8.75e-2)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (7.66e-3)" TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003037, HPA074642" Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 5 Mitochondria "HPA003037: AB_1080329, HPA074642: " "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Non-specific - Unknown function" "Cluster 33: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 15: Non-specific - Mixed function" Mitochondria "CAB017156: , HPA014589: AB_1858185, HPA048020: AB_2680234" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (5.01e-2)" "unprognostic (9.86e-2)" "unprognostic (1.21e-1)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "unprognostic (3.34e-2)" "unprognostic (6.98e-3)" TOR1AIP1 "FLJ13142, LAP1, LAP1B, LAP1C" ENSG00000143337 "Torsin 1A interacting protein 1" Q5JTV8 1 179882042-179920077 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 255.3;Late spermatids: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047151, HPA050546, HPA070991" Enhanced Supported "Nuclear membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Non-specific - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 11: Late spermatids - Unknown function" 7 "Nuclear membrane" "HPA047151: AB_2679956, HPA050546: AB_2681167, HPA070991: " "unprognostic (1.41e-1)" "unprognostic (3.95e-3)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (9.00e-2)" "unprognostic (6.33e-2)" "unprognostic (7.04e-2)" "unprognostic (8.62e-2)" "unprognostic (1.93e-1)" "unprognostic (9.10e-2)" "unprognostic (4.40e-2)" "unprognostic (4.41e-2)" "unprognostic (2.87e-1)" "unprognostic (7.75e-2)" "unprognostic (4.02e-2)" TOR1AIP2 "IFRG15, LULL1, NET9" ENSG00000169905 "Torsin 1A interacting protein 2" "Q8NFQ8, Q9H496" 1 179839967-179877803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051849, HPA058348, HPA070542" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 43: Hepatocytes - Metabolism" 7 "Endoplasmic reticulum" "HPA051849: AB_2681637, HPA058348: AB_2683687, HPA070542: AB_2686278" "unprognostic (1.22e-1)" "unprognostic (8.49e-3)" "unprognostic (2.61e-1)" "unprognostic (2.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.82e-1)" "unprognostic (6.17e-2)" "unprognostic (7.64e-3)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.99e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (1.36e-1)" TP53I11 PIG11 ENSG00000175274 "Tumor protein p53 inducible protein 11" O14683 11 44885903-44951306 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 477.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 41.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059727, HPA061276" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" "Endoplasmic reticulum, Golgi apparatus" "HPA059727: AB_2684113, HPA061276: AB_2684461" "prognostic unfavorable (7.33e-5)" "unprognostic (1.87e-1)" "unprognostic (4.03e-2)" "unprognostic (3.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.66e-1)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (6.55e-2)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" TPBG "5T4, 5T4-AG" ENSG00000146242 "Trophoblast glycoprotein" Q13641 6 82363206-82367420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 106.7;Extravillous trophoblasts: 94.2;Mesothelial cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010554 Enhanced Approved Nucleoplasm NA NA 310000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Nucleoplasm "HPA010554: AB_1858206" "unprognostic (3.03e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (6.68e-4)" "unprognostic (1.06e-1)" "unprognostic (4.52e-3)" "unprognostic (7.47e-3)" "unprognostic (8.55e-2)" "unprognostic (3.55e-3)" "unprognostic (8.39e-2)" "unprognostic (3.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.94e-1)" "unprognostic (3.77e-1)" "unprognostic (7.46e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (5.57e-2)" TPCN1 "FLJ20612, KIAA1169, TPC1" ENSG00000186815 "Two pore segment channel 1" Q9ULQ1 12 113221050-113298585 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.3;Microglial cells: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039757 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" 2 "HPA039757: AB_10795156" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" "unprognostic (7.34e-2)" "unprognostic (3.07e-2)" "unprognostic (1.32e-3)" "unprognostic (4.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.74e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.23e-1)" "unprognostic (9.08e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-3)" TPCN2 TPC2 ENSG00000162341 "Two pore segment channel 2" Q8NHX9 11 69048932-69136316 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 29.5;Inhibitory neurons: 21.5;Melanocytes: 41.2;Oligodendrocyte precursor cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016561, HPA027080" Supported Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Nucleoli "HPA016561: AB_1858207, HPA027080: AB_10600917" "unprognostic (1.29e-1)" "unprognostic (1.53e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (7.60e-2)" "unprognostic (7.04e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.15e-2)" "unprognostic (1.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-3)" "unprognostic (5.01e-2)" "unprognostic (4.88e-2)" TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10276.7;skeletal muscle: 12231.4;tongue: 4981.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 14867.7;Extravillous trophoblasts: 3617.1;Pancreatic endocrine cells: 3024.1;Skeletal myocytes: 5197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.9" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.9;monocytes: 19.2" "Cancer enhanced" "Detected in all" "testis cancer: 3510.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" 7 "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "thyroid gland: 1540.7" "Cell type enhanced" "Detected in some" "Adipocytes: 24.9;Endothelial cells: 14.3;Late spermatids: 7.3;Oocytes: 44.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 6 "Myeloma: 4.7;thyroid cancer: 6.1" "Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587, HPA073226" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Thyroid gland - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB009587: , HPA007987: AB_1080270, HPA073226: " "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" TPRA1 "FLJ32197, GPR175, TMEM227, TPRA40" ENSG00000163870 "Transmembrane protein adipocyte associated 1" Q86W33 3 127571232-127598267 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 221.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019784 Approved Approved Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Dendritic cells - Antigen presentation" Vesicles "HPA019784: AB_2670266" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-3)" "unprognostic (1.66e-2)" "unprognostic (6.91e-3)" "unprognostic (9.74e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (1.73e-2)" "unprognostic (4.42e-2)" "unprognostic (2.09e-1)" "unprognostic (4.28e-2)" TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 14.0" "Cell type enriched" "Detected in some" 8 "Intestinal goblet cells: 273.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.6" "Adipose subcutaneous - Mast cells, Breast - Breast glandular cells" "Not detected" "Not detected" HPA060458 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA060458: AB_2684283" "unprognostic (1.86e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-3)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.76e-8)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.65e-4)" "unprognostic (5.70e-2)" TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 193 "testis: 109.7" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 15.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.7" "Testis - Spermatocytes" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" TPTE2 TPIP ENSG00000132958 "Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" Q6XPS3 13 19422876-19561625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 7.1" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 11.6;Excitatory neurons: 4.4;Inhibitory neurons: 6.0;Microglial cells: 3.6;Oligodendrocyte precursor cells: 7.1;Oligodendrocytes: 3.4;Spermatocytes: 12.6" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "Bone cancer: 22.3" "Testis - Early spermatids" "Not detected" "Not detected" HPA068342 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 31: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA068342: AB_2685976" "unprognostic (2.50e-1)" "unprognostic (2.10e-1)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (5.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-1)" "unprognostic (1.05e-12)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" TRABD PP2447 ENSG00000170638 "TraB domain containing" Q9H4I3 22 50185913-50199598 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000822 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 28: Dendritic cells - Antigen presentation" "Nucleoplasm, Mitochondria" "HPA000822: AB_10959384" "unprognostic (9.37e-2)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.19e-5)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-3)" "unprognostic (6.12e-2)" "unprognostic (2.40e-1)" "unprognostic (4.68e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.08e-3)" "unprognostic (1.19e-1)" "unprognostic (2.87e-2)" "unprognostic (2.98e-3)" TRABD2A "C2orf89, TIKI1" ENSG00000186854 "TraB domain containing 2A" Q86V40 2 84821650-84907008 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 41.4;lymphoid tissue: 11.1;ovary: 39.2" "Group enriched" "Detected in many" 4 "Early spermatids: 582.7;Late spermatids: 353.4" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 14.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 72.1" "Lineage enriched" "Detected in many" 18 "T-cells: 72.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 63.9;colorectal cancer: 35.7" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" HPA045817 Approved "Intracellular and membrane" Enzyme NA NA 18000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" "HPA045817: AB_2679460" "unprognostic (7.49e-3)" "unprognostic (3.35e-1)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (3.82e-5)" "unprognostic (2.46e-2)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.47e-4)" "unprognostic (4.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.41e-3)" "unprognostic (1.37e-1)" TRAF3IP2 "ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522" ENSG00000056972 "TRAF3 interacting protein 2" O43734 6 111555381-111606906 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA036352 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 35: RS4;11 - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 "Golgi apparatus" Vesicles "HPA036352: AB_10672085" "unprognostic (1.94e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-1)" "prognostic favorable (4.73e-5)" "unprognostic (2.81e-2)" "unprognostic (3.03e-2)" "unprognostic (1.01e-2)" "unprognostic (9.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.13e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (1.11e-1)" "unprognostic (4.88e-1)" "unprognostic (2.34e-2)" "unprognostic (1.31e-1)" TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 127.0" "Cell type enhanced" "Detected in many" "B-cells: 124.2;dendritic cells: 58.4;granulocytes: 68.9;monocytes: 68.3;NK-cells: 232.3;T-cells: 153.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 48.6;lymphoma: 38.1;Myeloma: 70.7" "Adipose subcutaneous - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Uncertain Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 45 Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 883.3;Plasma cells: 628.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" 2 "HPA023929: AB_1858239" "unprognostic (3.85e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (8.34e-3)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (5.93e-2)" "unprognostic (8.94e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.39e-3)" "unprognostic (3.61e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (7.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" TRAM1L1 MGC26568 ENSG00000174599 "Translocation associated membrane protein 1 like 1" Q8N609 4 117083554-117085576 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 6.8;Oligodendrocyte precursor cells: 7.5;Oligodendrocytes: 12.6;Prostatic glandular cells: 6.6;Spermatogonia: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044560 Uncertain Uncertain Mitochondria NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 20 Mitochondria "HPA044560: AB_10796097" "unprognostic (9.06e-2)" "unprognostic (2.87e-2)" "unprognostic (4.40e-2)" "unprognostic (2.17e-3)" "unprognostic (9.77e-2)" "unprognostic (2.37e-2)" "unprognostic (5.97e-2)" "unprognostic (3.02e-1)" "unprognostic (1.14e-1)" "unprognostic (3.25e-1)" "unprognostic (1.09e-3)" "unprognostic (1.56e-2)" "unprognostic (2.76e-2)" "unprognostic (1.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" TRAM2 KIAA0057 ENSG00000065308 "Translocation associated membrane protein 2" Q15035 6 52497408-52577060 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 124.4;Oocytes: 64.7;Plasma cells: 85.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035092, HPA057925" Approved Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" Cytosol "HPA035092: AB_10610562, HPA057925: AB_2683557" "unprognostic (2.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (1.12e-1)" "unprognostic (4.07e-2)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.03e-1)" "unprognostic (3.01e-1)" "unprognostic (5.05e-1)" "prognostic unfavorable (1.41e-9)" "unprognostic (1.37e-2)" "unprognostic (1.60e-1)" "unprognostic (6.64e-2)" "unprognostic (1.19e-2)" TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 97.9;breast: 66.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA050825 Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 77.8" "Cell type enriched" "Detected in some" 15 "T-cells: 119.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 396.7" "Group enriched" "Detected in many" 155 "granulocytes: 396.7;T-cells: 314.1" "Cancer enhanced" "Detected in some" "Leukemia: 10.3;Myeloma: 2.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" TRDN TRISK ENSG00000186439 Triadin Q13061 6 123216339-123637093 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 406.7;skeletal muscle: 1874.3;tongue: 979.0" "Group enriched" "Detected in many" 15 "Cardiomyocytes: 1535.5;Muller glia cells: 589.5;Skeletal myocytes: 2049.2" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.2;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Rhabdoid: 16.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Region enriched" "Detected in some" 10 "olfactory bulb: 11.0" "Region enriched" "Detected in some" 24 "olfactory bulb: 40.1" "HPA038226, HPA058226" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" Nucleoplasm "HPA038226: AB_10795574, HPA058226: AB_2683643" "unprognostic (1.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.20e-2)" "unprognostic (3.06e-3)" "unprognostic (2.40e-1)" "unprognostic (2.38e-1)" "unprognostic (2.42e-1)" "unprognostic (8.42e-2)" "unprognostic (8.71e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (2.55e-2)" "unprognostic (3.97e-2)" TREM1 "CD354, TREM-1" ENSG00000124731 "Triggering receptor expressed on myeloid cells 1" Q9NP99 6 41267926-41286682 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.0;lung: 63.3;lymphoid tissue: 42.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 121.6;Macrophages: 117.6;monocytes: 389.2" "Cancer enhanced" "Detected in many" "lung cancer: 9.6" "Region enhanced" "Detected in many" "cerebral cortex: 16.3" "Immune cell enriched" "Detected in many" 7 "neutrophil: 616.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 616.7" "Cancer enhanced" "Detected in some" "testis cancer: 5.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005563, HPA053612" Approved Approved "Golgi apparatus" "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "HPA005563: AB_1858259, HPA053612: " "unprognostic (6.41e-2)" "unprognostic (1.47e-3)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (6.07e-3)" "unprognostic (2.97e-2)" "unprognostic (5.73e-5)" "unprognostic (1.29e-1)" "unprognostic (1.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.24e-3)" "unprognostic (7.65e-2)" "unprognostic (3.18e-7)" "unprognostic (6.32e-3)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (7.26e-2)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.5;choroid plexus: 56.7" "Cell type enriched" "Detected in some" 8 "Hofbauer cells: 905.9" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4;Leukemia: 2.6;testis cancer: 1.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Sebaceous gland cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" Receptor NA NA 50000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 3 Vesicles "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149337-41154347 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 8.1;brain: 2.9;choroid plexus: 2.2;lung: 2.0;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "B-cells: 1.4;dendritic cells: 1.8;Hofbauer cells: 3.5;Langerhans cells: 2.3;Macrophages: 1.7;Microglial cells: 6.3;NK-cells: 2.2" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 91.2" "Lineage enriched" "Detected in many" 51 "granulocytes: 91.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 43000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 1 "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: AB_1858262, HPA017860: AB_1858261" "unprognostic (6.70e-2)" "unprognostic (3.50e-3)" "unprognostic (1.15e-3)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (4.53e-5)" "unprognostic (1.10e-2)" "unprognostic (2.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.12e-3)" "unprognostic (2.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.11e-4)" "unprognostic (1.36e-1)" "unprognostic (8.38e-2)" "unprognostic (7.51e-2)" "unprognostic (3.41e-2)" TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 2.0" "Cell type enhanced" "Detected in single" "monocytes: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 3.5" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA065044: AB_2685411" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (5.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-4)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-2)" TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 76.9" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Basal squamous epithelial cells: 2.9;Excitatory neurons: 2.2;Gastric mucus-secreting cells: 2.4;Microglial cells: 5.4;Oligodendrocytes: 5.5;Plasma cells: 3.2;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 49: Non-specific - Transcription" Cytosol "HPA035437: AB_10672092, HPA046721: AB_2732531" TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086585-109121565 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055162 Approved NA NA "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Neurons - Synaptic function" 13 "HPA055162: AB_2732592" "unprognostic (1.92e-2)" "unprognostic (8.58e-2)" "unprognostic (1.17e-1)" TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716910-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 107.3;Leydig cells: 79.3;Muller glia cells: 93.7;Peritubular cells: 73.7" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.7" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.7" "Cancer enhanced" "Detected in all" "Neuroblastoma: 129.2;skin cancer: 129.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 2 Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" TRIM13 "DLEU5, Leu5, RFP2, RNF77" ENSG00000204977 "Tripartite motif containing 13" O60858 13 49995888-50020481 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 736.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000367 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA000367: AB_1856196" "unprognostic (1.14e-1)" "unprognostic (8.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.23e-3)" "unprognostic (4.75e-3)" "unprognostic (5.01e-2)" "unprognostic (4.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.44e-1)" "unprognostic (5.07e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-2)" "unprognostic (9.01e-2)" "unprognostic (2.37e-2)" "unprognostic (1.55e-2)" TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 59.6;liver: 36.8;skeletal muscle: 28.5;tongue: 32.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 160.0;Skeletal myocytes: 142.5" "Group enriched" "Detected in some" 10 "liver cancer: 12.3;renal cancer: 5.8" "Region enhanced" "Detected in some" "cerebellum: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Kidney cancer: 39.2;Rhabdoid: 58.1;testis cancer: 83.9" "Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons: 1.1" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "Golgi apparatus" Cytosol "HPA038793: AB_10673289, HPA053691: AB_2682231" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.77e-3)" "unprognostic (8.31e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (5.18e-2)" "unprognostic (2.10e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-2)" "unprognostic (1.77e-3)" TRIM59 "Mrf1, RNF104, TRIM57, TSBF1" ENSG00000213186 "Tripartite motif containing 59" Q8IWR1 3 160432445-160485773 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0;lymphoid tissue: 13.3" "Cell type enriched" "Detected in many" 14 "Oligodendrocytes: 364.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017750 Uncertain Approved "Rods & Rings" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" 15 "Rods & Rings" "HPA017750: AB_1858312" "unprognostic (3.74e-1)" "prognostic favorable (4.36e-4)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (8.00e-4)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.02e-3)" "unprognostic (2.44e-11)" "unprognostic (7.92e-2)" "unprognostic (2.42e-1)" "unprognostic (4.03e-2)" "unprognostic (5.91e-3)" TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 88.9;Excitatory neurons: 139.6;Inhibitory neurons: 176.7;Microglial cells: 47.4;Oligodendrocyte precursor cells: 145.3;Oligodendrocytes: 153.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 3 Vesicles "CAB009387: AB_2240941, HPA021130: AB_1858361" "unprognostic (1.66e-1)" "unprognostic (7.38e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-5)" "unprognostic (5.53e-1)" "unprognostic (1.40e-2)" "unprognostic (5.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (1.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" TRPC6 "FSGS2, TRP6" ENSG00000137672 "Transient receptor potential cation channel subfamily C member 6" Q9Y210 11 101451564-101872562 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.9;placenta: 20.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.6;Inhibitory neurons: 45.0;Microglial cells: 11.6;Smooth muscle cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.4;testis cancer: 1.9" "Adipose subcutaneous - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045098 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA045098: AB_10959600" "unprognostic (1.45e-1)" "unprognostic (4.21e-1)" "unprognostic (2.43e-1)" "unprognostic (8.71e-5)" "unprognostic (1.86e-1)" "unprognostic (1.36e-2)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (5.47e-4)" "unprognostic (1.99e-3)" "unprognostic (4.88e-2)" "unprognostic (7.16e-2)" "unprognostic (1.32e-2)" TRPC7 ENSG00000069018 "Transient receptor potential cation channel subfamily C member 7" Q9HCX4 5 136212745-136365545 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.2;Enteroendocrine cells: 3.4;Inhibitory neurons: 9.7;Oocytes: 6.6;Proximal tubular cells: 5.4;Spermatocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB022592, HPA031126" Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "CAB022592: , HPA031126: AB_10603221" "unprognostic (1.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.03e-2)" "unprognostic (2.89e-5)" "unprognostic (3.26e-1)" "unprognostic (2.75e-1)" "unprognostic (9.99e-2)" "unprognostic (1.77e-1)" "unprognostic (6.78e-2)" TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001065-31161160 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 17.0;skin 1: 4.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 579.2;Melanocytes: 226.8" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 248 "skin cancer: 38.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Melanocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 25: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" TRPM2 "EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7" ENSG00000142185 "Transient receptor potential cation channel subfamily M member 2" O94759 21 44350163-44443081 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sodium transport, Transport" "Calcium channel, Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.9" "Cell type enhanced" "Detected in many" "dendritic cells: 25.2;Excitatory neurons: 50.9;Hofbauer cells: 17.0;Inhibitory neurons: 43.3;Macrophages: 19.3;Microglial cells: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.2" "Group enriched" "Detected in many" 4 "dendritic cells: 10.2;monocytes: 5.6" "Cancer enriched" "Detected in many" 7 "Leukemia: 36.7" "Adipose visceral - Macrophages, Kidney - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035260 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA035260: AB_2674540" "unprognostic (3.61e-2)" "unprognostic (2.18e-1)" "unprognostic (7.55e-2)" "prognostic favorable (9.28e-4)" "unprognostic (6.49e-2)" "unprognostic (4.54e-2)" "unprognostic (5.17e-2)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (2.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.40e-1)" "unprognostic (3.31e-2)" "unprognostic (8.88e-3)" "prognostic favorable (7.59e-4)" TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "choroid plexus: 676.9" "Cell type enhanced" "Detected in many" "Astrocytes: 858.3;Excitatory neurons: 376.7;Inhibitory neurons: 179.3;Muller glia cells: 155.8;Oligodendrocyte precursor cells: 99.0" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Region enriched" "Detected in all" 15 "choroid plexus: 1433.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.1;Rhabdoid: 10.6" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 183.0;Hepatocytes: 90.1;Intestinal goblet cells: 84.0;Prostatic glandular cells: 86.0" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 8 "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 105.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 43.6;Hofbauer cells: 48.8;Macrophages: 34.8;Melanocytes: 51.5;NK-cells: 30.6" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 81.4" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.1;skeletal muscle: 1.5;skin 1: 4.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Plasma cells: 14.2;Proximal enterocytes: 21.8;Schwann cells: 15.1;Skeletal myocytes: 8.8;Suprabasal keratinocytes: 13.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 71.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Cholangiocytes: 15.3;Ciliated cells: 18.7;Cytotrophoblasts: 19.4;Ionocytes: 19.1;Kupffer cells: 14.6;Salivary duct cells: 15.0;Serous glandular cells: 15.4;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 12 "choroid plexus: 107.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 10.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" HPA007150 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" TRPV5 "CaT2, ECAC1" ENSG00000127412 "Transient receptor potential cation channel subfamily V member 5" Q9NQA5 7 142908101-142933746 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 1.6;kidney: 4.3" "Cell type enriched" "Detected in some" 7 "Oligodendrocytes: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063175 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 66: Non-specific - Mitochondria" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA063175: AB_2684954" "unprognostic (7.44e-2)" "unprognostic (3.93e-2)" "unprognostic (1.22e-2)" "unprognostic (4.20e-2)" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.78e-2)" "unprognostic (1.07e-1)" "unprognostic (7.95e-2)" "unprognostic (7.73e-4)" "unprognostic (4.87e-2)" "unprognostic (3.41e-1)" "unprognostic (4.58e-1)" "unprognostic (7.76e-3)" TRPV6 "CaT1, ECAC2" ENSG00000165125 "Transient receptor potential cation channel subfamily V member 6" Q9H1D0 7 142871208-142885745 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 37.2;prostate: 22.7;salivary gland: 67.4" "Cell type enhanced" "Detected in many" "Ductal cells: 90.1;Exocrine glandular cells: 22.6;Late spermatids: 40.9;Prostatic glandular cells: 53.4;Serous glandular cells: 68.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.9;prostate cancer: 11.5" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA062864 Approved NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA062864: AB_2684885" "unprognostic (9.85e-2)" "unprognostic (1.60e-2)" "unprognostic (6.29e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "unprognostic (5.43e-2)" "unprognostic (3.50e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-2)" "unprognostic (3.27e-2)" "unprognostic (8.49e-2)" "unprognostic (9.39e-3)" "unprognostic (1.69e-1)" "unprognostic (7.17e-3)" "unprognostic (3.53e-2)" TRRAP "PAF400, TR-AP, Tra1" ENSG00000196367 "Transformation/transcription domain associated protein" Q9Y4A5 7 98877933-99050831 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054376 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 5 Nucleoplasm "Golgi apparatus" "HPA054376: AB_2682467" "unprognostic (2.10e-1)" "unprognostic (7.79e-2)" "unprognostic (2.21e-1)" "unprognostic (4.35e-2)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.40e-2)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "unprognostic (9.45e-2)" "unprognostic (7.02e-2)" "unprognostic (2.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" TSBP1 "C6orf10, TSBP" ENSG00000204296 "Testis expressed basic protein 1" Q5SRN2 6 32288526-32371907 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 154 "testis: 33.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 552.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA047479, HPA057426" Approved Uncertain "Endoplasmic reticulum" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Early spermatids - Unknown function" "Endoplasmic reticulum" "HPA047479: , HPA057426: " "unprognostic (1.00e-1)" "unprognostic (2.24e-1)" "unprognostic (1.05e-1)" "unprognostic (5.63e-2)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.55e-1)" "unprognostic (4.32e-4)" "unprognostic (2.42e-1)" "unprognostic (8.19e-2)" "unprognostic (6.56e-2)" TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 406.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 36: Late spermatids - Unknown function" 12 Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 143.0;Horizontal cells: 124.0;Rod photoreceptor cells: 158.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 3: Basal prostatic cells - Lipid metabolism" 9 Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 265.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 6.7;Inhibitory neurons: 11.8;Langerhans cells: 7.2;Microglial cells: 6.3;Oligodendrocytes: 8.8;Plasma cells: 14.3" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cancer enhanced" "Detected in some" "Myeloma: 10.0" "Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.8" CAB000473 Approved "Intracellular and membrane" Receptor NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 61: Plasma cells - Immunoglobulins & histones" 4 "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" TSN "BCLF-1, REHF-1, TRSLN" ENSG00000211460 Translin Q15631 2 121737103-121767853 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059561 Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 280000 "Cluster 25: Non-specific - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 10 "Nucleoplasm, Endoplasmic reticulum" "HPA059561: AB_2684063" "unprognostic (3.15e-2)" "unprognostic (1.83e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (7.05e-4)" "unprognostic (7.13e-3)" "unprognostic (3.12e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (2.32e-2)" "unprognostic (7.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.04e-2)" "unprognostic (3.42e-2)" "unprognostic (3.18e-1)" TSNARE1 FLJ31164 ENSG00000171045 "T-SNARE domain containing 1" Q96NA8 8 142212080-142403182 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.8;Inhibitory neurons: 22.1;Oligodendrocyte precursor cells: 19.8;Oligodendrocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074249 Approved Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA074249: " "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.94e-3)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (1.09e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-3)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.87e-3)" "unprognostic (1.66e-1)" "unprognostic (6.26e-2)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (1.29e-1)" "prognostic favorable (7.33e-4)" TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 573.8;kidney: 237.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 992.2;Club cells: 705.5;Distal enterocytes: 2274.7;Intestinal goblet cells: 730.3;Ionocytes: 1033.4;Late spermatids: 805.6;Paneth cells: 807.5" "Cancer enhanced" "Detected in all" "prostate cancer: 455.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 217.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 45: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 3 "Nucleoplasm, Vesicles" "HPA011909: AB_2668565" "unprognostic (1.21e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (4.12e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.28e-6)" "unprognostic (5.90e-2)" "unprognostic (2.61e-1)" "unprognostic (4.90e-2)" "unprognostic (4.30e-2)" TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.1" "Cell type enhanced" "Detected in some" "Late spermatids: 11.3;Lymphatic endothelial cells: 21.8;Oligodendrocyte precursor cells: 25.5;Schwann cells: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 11.3;Neuroblastoma: 12.5;testis cancer: 10.3" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 88.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.5;Collecting duct cells: 93.4;Distal tubular cells: 141.4;Glandular and luminal cells: 90.9;Proximal tubular cells: 90.7" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatocytes, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 21 Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" TSPAN13 "NET-6, TM4SF13" ENSG00000106537 "Tetraspanin 13" O95857 7 16753755-16784536 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 295.2;Alveolar cells type 1: 429.5;Cytotrophoblasts: 291.2;dendritic cells: 370.5;Intestinal goblet cells: 367.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 99.9;plasmacytoid DC: 232.1" "Group enriched" "Detected in many" 42 "B-cells: 99.9;dendritic cells: 232.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007426 Uncertain Uncertain Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA007426: AB_10603137" "unprognostic (3.22e-1)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.56e-5)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (5.69e-2)" "unprognostic (6.63e-2)" "prognostic favorable (2.20e-4)" "unprognostic (1.50e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454265-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 27: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "HPA014773: AB_2208670, HPA057174: " "unprognostic (7.52e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.55e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (8.90e-2)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (5.15e-3)" "unprognostic (4.12e-3)" "prognostic favorable (4.20e-4)" "unprognostic (2.52e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (2.57e-3)" TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.7;Ductal cells: 110.5;Exocrine glandular cells: 113.7;Schwann cells: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" TSPAN16 "TM-8, TM4-B, TM4SF16" ENSG00000130167 "Tetraspanin 16" Q9UKR8 19 11296139-11326996 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 130.9" "Cell type enriched" "Detected in some" 8 "Late spermatids: 4882.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "basophil: 16.6;eosinophil: 19.2;neutrophil: 37.6" "Lineage enriched" "Detected in many" 17 "granulocytes: 37.6" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA076551 Enhanced Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 20: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" "Plasma membrane" "HPA076551: " "unprognostic (1.06e-1)" "unprognostic (2.82e-2)" "unprognostic (1.73e-2)" "unprognostic (4.74e-3)" "unprognostic (1.53e-1)" "unprognostic (2.06e-3)" "unprognostic (1.37e-1)" "unprognostic (2.21e-1)" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (8.69e-4)" "unprognostic (8.81e-8)" "unprognostic (1.98e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-3)" "unprognostic (2.67e-1)" TSPAN17 "FBX23, FBXO23, TM4SF17" ENSG00000048140 "Tetraspanin 17" Q96FV3 5 176647387-176659054 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030447 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Non-specific - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 1: Erythroid cells - Oxygen transport" "HPA030447: AB_2673484" "unprognostic (1.70e-2)" "unprognostic (7.92e-2)" "unprognostic (2.91e-1)" "unprognostic (3.47e-2)" "unprognostic (3.97e-2)" "unprognostic (3.71e-3)" "unprognostic (1.21e-3)" "unprognostic (3.82e-1)" "unprognostic (2.30e-1)" "unprognostic (3.60e-1)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.41e-2)" "unprognostic (7.11e-3)" "unprognostic (2.32e-1)" "unprognostic (4.50e-1)" "unprognostic (1.46e-1)" TSPAN19 ENSG00000231738 "Tetraspanin 19" P0C672 12 85014311-85036277 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 4.2;testis: 4.3" "Group enriched" "Detected in some" 4 "Ciliated cells: 120.0;Early spermatids: 107.3;Ionocytes: 58.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA057066 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 65: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "HPA057066: AB_2683325" "unprognostic (1.94e-1)" "unprognostic (9.81e-4)" "unprognostic (8.57e-2)" "unprognostic (8.37e-2)" "unprognostic (2.33e-1)" "unprognostic (6.57e-2)" "unprognostic (2.26e-3)" "unprognostic (9.52e-2)" "unprognostic (5.09e-3)" "unprognostic (2.22e-1)" "unprognostic (3.78e-2)" TSPAN2 "FLJ12082, TSN2, TSPAN-2" ENSG00000134198 "Tetraspanin 2" O60636 1 115048011-115089503 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 45.8;intestine: 53.5" "Cell type enhanced" "Detected in many" "NK-cells: 29.8;Pancreatic endocrine cells: 73.0;Smooth muscle cells: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 109.9;eosinophil: 56.0;neutrophil: 110.4;NK-cell: 86.6" "Group enriched" "Detected in many" 4 "granulocytes: 110.4;NK-cells: 86.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "white matter: 842.8" "Low region specificity" "Detected in all" "HPA015640, HPA073306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Smooth muscle cells - Muscle contraction" 34 Nucleoplasm "HPA015640: AB_1858405, HPA073306: " "unprognostic (4.56e-2)" "unprognostic (6.86e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (1.57e-3)" "unprognostic (1.64e-1)" "unprognostic (9.73e-6)" "unprognostic (6.06e-3)" "unprognostic (3.07e-2)" "unprognostic (4.74e-2)" "unprognostic (7.66e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.48e-7)" "unprognostic (5.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.48e-3)" "unprognostic (7.80e-3)" TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 608.3;Mesothelial cells: 489.5;Muller glia cells: 467.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 482.8;naive B-cell: 490.1;plasmacytoid DC: 313.6" "Group enriched" "Detected in all" 5 "B-cells: 490.1;dendritic cells: 313.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 5 "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 19.7;heart muscle: 11.0;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.7;Erythroid cells: 21.7;granulocytes: 21.3;Langerhans cells: 24.5;monocytes: 36.2;NK-cells: 67.2;T-cells: 19.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 9.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" Nucleoplasm "HPA024135: AB_1858409" "unprognostic (7.50e-3)" "unprognostic (4.88e-4)" "unprognostic (1.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.45e-3)" "unprognostic (2.10e-4)" "unprognostic (7.72e-3)" "unprognostic (8.25e-3)" "unprognostic (9.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (4.20e-1)" "unprognostic (4.35e-1)" "unprognostic (8.13e-2)" TSPAN33 "MGC50844, Penumbra" ENSG00000158457 "Tetraspanin 33" Q86UF1 7 129144707-129169699 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 63.0" "Cell type enhanced" "Detected in many" "B-cells: 39.0;Langerhans cells: 106.0;Macrophages: 35.3;Peritubular cells: 31.1;Proximal tubular cells: 46.8;Schwann cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.1;naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "lymphoma: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020357 Enhanced Approved Microtubules NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 23 Microtubules "HPA020357: AB_1858410" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-2)" "unprognostic (5.62e-2)" "unprognostic (2.29e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (2.66e-1)" "prognostic favorable (8.88e-4)" "unprognostic (1.67e-1)" "prognostic favorable (8.74e-5)" "unprognostic (2.50e-2)" "unprognostic (2.73e-1)" "unprognostic (1.55e-2)" "unprognostic (1.16e-2)" TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 350.0;Inhibitory neurons: 238.1;Microglial cells: 187.0;Oligodendrocytes: 546.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079522 Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" 1 "Plasma membrane, Actin filaments" Nucleoplasm "HPA079522: " "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-3)" "unprognostic (2.65e-1)" "unprognostic (2.44e-3)" "unprognostic (1.41e-2)" "unprognostic (1.54e-2)" "unprognostic (9.27e-2)" "unprognostic (1.79e-1)" "unprognostic (3.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.83e-5)" "prognostic unfavorable (8.56e-4)" "unprognostic (2.15e-1)" "unprognostic (3.23e-3)" "unprognostic (1.23e-1)" TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 7 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 480.8" "Cell type enhanced" "Detected in many" "Astrocytes: 260.7;Cone photoreceptor cells: 156.3;Endothelial cells: 163.0;Excitatory neurons: 208.4;Inhibitory neurons: 238.7;Oligodendrocyte precursor cells: 331.6" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 60.4;Neuroblastoma: 61.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 919.6;stomach 1: 614.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3097.9;Ductal cells: 947.7;Enteroendocrine cells: 836.8;Intestinal goblet cells: 813.6;Paneth cells: 1988.4;Proximal enterocytes: 3369.5;Undifferentiated cells: 1654.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 618.1;Gastric cancer: 461.0" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.0;heart muscle: 124.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.2;Extravillous trophoblasts: 116.0;Syncytiotrophoblasts: 74.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 198.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 80.5" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS, TSPO1" ENSG00000100300 "Translocator protein" P30536 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 670.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1357.2;Suprabasal keratinocytes: 1573.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 58: Macrophages - Innate immune response" 13 Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" TSPO2 "BZRPL1, dJ34B21.2" ENSG00000112212 "Translocator protein 2" Q5TGU0 6 41042467-41044337 "Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 49.5" "Cell type enriched" "Detected in some" 72 "Erythroid cells: 155.0" "Cancer enhanced" "Detected in some" "liver cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060691, HPA066996" Enhanced "Plasma membrane" NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 49 "Plasma membrane" "HPA060691: , HPA066996: AB_2685761" "unprognostic (1.89e-3)" "unprognostic (8.35e-3)" "unprognostic (2.57e-3)" "unprognostic (2.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-2)" "unprognostic (6.61e-3)" "unprognostic (2.29e-1)" "unprognostic (3.37e-1)" "unprognostic (2.89e-1)" "unprognostic (2.71e-1)" "unprognostic (4.92e-2)" "unprognostic (1.86e-2)" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (5.37e-2)" "unprognostic (1.76e-2)" TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432553-113434989 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 224 "testis: 52.1" "Group enriched" "Detected in some" 181 "Early spermatids: 394.7;Late spermatids: 1090.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA027827 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 61: BICR 18 - Protein kinases" "Cluster 36: Late spermatids - Unknown function" 5 "HPA027827: AB_10603138" TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205696-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 37.0" "Cell type enriched" "Detected in some" 10 "Early spermatids: 339.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 18: Early spermatids - Unknown function" 1 "Cell Junctions" "HPA060660: AB_2684339, HPA077103: AB_2732332" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" TTC13 FLJ22584 ENSG00000143643 "Tetratricopeptide repeat domain 13" Q8NBP0 1 230906243-230978875 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.6;Excitatory neurons: 68.5;Inhibitory neurons: 73.6;Microglial cells: 53.7;Oligodendrocyte precursor cells: 39.1;Oligodendrocytes: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018022, HPA051558" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 19: NK-cells - Adaptive immune response" Nucleoplasm "HPA018022: AB_2211524, HPA051558: AB_2681534" "unprognostic (2.68e-1)" "unprognostic (1.64e-1)" "unprognostic (3.42e-1)" "unprognostic (9.59e-3)" "unprognostic (8.10e-2)" "prognostic favorable (7.66e-4)" "unprognostic (2.60e-2)" "unprognostic (5.40e-3)" "unprognostic (1.97e-1)" "unprognostic (1.80e-2)" "prognostic favorable (4.59e-5)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.60e-11)" "unprognostic (4.48e-2)" "unprognostic (3.01e-1)" "unprognostic (5.96e-2)" "unprognostic (7.54e-3)" TTC14 "FLJ00166, KIAA1980" ENSG00000163728 "Tetratricopeptide repeat domain 14" Q96N46 3 180602163-180617828 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009295 Uncertain Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Neuronal - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA009295: AB_1858425" "unprognostic (2.72e-1)" "unprognostic (4.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.59e-2)" "unprognostic (1.48e-2)" "unprognostic (1.54e-1)" "unprognostic (2.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.91e-2)" "unprognostic (2.01e-1)" "unprognostic (3.63e-1)" "unprognostic (2.22e-3)" "unprognostic (2.27e-3)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (8.07e-2)" "unprognostic (2.33e-3)" TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: AB_2675049" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" TTC33 OSRF ENSG00000113638 "Tetratricopeptide repeat domain 33" Q6PID6 5 40512333-40755963 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038252, HPA038253" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 9 Nucleoplasm "Golgi apparatus, Vesicles" "HPA038252: AB_10674551, HPA038253: AB_10671739" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (3.41e-3)" "unprognostic (1.04e-3)" "unprognostic (3.01e-2)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.50e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-2)" "unprognostic (4.28e-3)" TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 57.8" "Group enriched" "Detected in many" 8 "Early spermatids: 395.7;Late spermatids: 628.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 47 "plasmacytoid DC: 31.8" "Lineage enriched" "Detected in single" 47 "dendritic cells: 31.8" "Cancer enhanced" "Detected in many" "breast cancer: 65.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" TTC39B "C9orf52, FLJ33868" ENSG00000155158 "Tetratricopeptide repeat domain 39B" Q5VTQ0 9 15163622-15307360 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 54.0;Inhibitory neurons: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cells: 8.1;T-cells: 7.4" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063162 Approved "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" 1 "Endoplasmic reticulum" "HPA063162: AB_2684952" "unprognostic (1.64e-1)" "unprognostic (9.32e-3)" "unprognostic (1.47e-2)" "unprognostic (7.89e-2)" "unprognostic (7.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.12e-2)" "prognostic favorable (9.64e-6)" "unprognostic (5.99e-2)" "unprognostic (4.77e-2)" "unprognostic (1.59e-1)" "unprognostic (6.89e-2)" "prognostic favorable (4.08e-7)" "unprognostic (3.31e-3)" "unprognostic (2.12e-2)" "unprognostic (5.19e-2)" "unprognostic (1.48e-1)" TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.9;retina: 138.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 179.9;Late spermatids: 323.5;Rod photoreceptor cells: 202.1" "Cancer enriched" "Detected in all" 4 "liver cancer: 19.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 115.6" "Lineage enriched" "Detected in all" 4 "T-cells: 115.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm "HPA065705: AB_2685538, HPA065713: AB_2685542" "prognostic favorable (1.48e-4)" "unprognostic (6.37e-2)" "unprognostic (3.66e-1)" "unprognostic (9.97e-2)" "unprognostic (4.37e-2)" "unprognostic (2.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" "unprognostic (8.94e-3)" "unprognostic (4.48e-3)" TTI2 "C8orf41, FLJ23263" ENSG00000129696 "TELO2 interacting protein 2" Q6NXR4 8 33473386-33513185 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 30.6;Spermatocytes: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023523, HPA029823" Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 1 Centrosome Nucleoplasm "HPA023523: AB_1845776, HPA029823: AB_10602337" "unprognostic (6.30e-2)" "unprognostic (3.09e-2)" "unprognostic (9.34e-3)" "unprognostic (5.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.13e-2)" "unprognostic (4.25e-3)" "unprognostic (2.64e-1)" "unprognostic (3.10e-1)" "unprognostic (2.97e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (3.27e-3)" "unprognostic (1.07e-2)" "unprognostic (2.05e-1)" "unprognostic (1.94e-1)" "unprognostic (9.35e-2)" TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 161.7;skeletal muscle: 887.9;tongue: 355.2" "Group enriched" "Detected in many" 80 "Cardiomyocytes: 42687.1;Skeletal myocytes: 19073.0" "Cancer enriched" "Detected in single" 4 "head and neck cancer: 1.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Sarcoma: 3.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 16000000 "Cluster 24: Non-specific - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 13 "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 462.2" "Cell type enhanced" "Detected in many" "Astrocytes: 244.3;Bipolar cells: 133.3;Muller glia cells: 603.0;Rod photoreceptor cells: 141.3;Schwann cells: 153.0;Secretory cells: 226.1" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 10: Muller glia cells - Visual perception" 1 "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" TTYH3 KIAA1691 ENSG00000136295 "Tweety family member 3" Q9C0H2 7 2631961-2664802 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 124.9;Kupffer cells: 76.1;Macrophages: 68.3;Melanocytes: 63.6;monocytes: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.9;non-classical monocyte: 8.4" "Lineage enriched" "Detected in many" 5 "monocytes: 9.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053520 Uncertain NA NA 55000 "Cluster 40: Monocytes - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" "HPA053520: AB_2682176" "unprognostic (2.53e-2)" "unprognostic (6.65e-3)" "unprognostic (3.86e-3)" "unprognostic (1.35e-1)" "unprognostic (5.25e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (2.53e-5)" "unprognostic (5.53e-2)" "unprognostic (1.96e-1)" "unprognostic (8.59e-3)" "unprognostic (5.40e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.58e-5)" "unprognostic (7.90e-2)" "unprognostic (5.45e-2)" "unprognostic (1.03e-1)" "unprognostic (8.85e-2)" TUBA8 TUBAL2 ENSG00000183785 "Tubulin alpha 8" Q9NY65 22 18110100-18146683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3;skeletal muscle: 320.5;tongue: 148.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Excitatory neurons: 7.8;Horizontal cells: 1.9;Inhibitory neurons: 5.4;Oligodendrocyte precursor cells: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 2.8;eosinophil: 2.7;neutrophil: 5.0;NK-cell: 10.4" "Group enriched" "Detected in many" 7 "granulocytes: 5.0;NK-cells: 10.4" "Cancer enhanced" "Detected in many" "Leukemia: 10.1;skin cancer: 10.2" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "cerebellum: 54.7;olfactory bulb: 54.0" "Low region specificity" "Detected in all" "HPA043684, CAB046031, HPA063394" Approved Supported Microtubules NA NA 80000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 Microtubules "CAB046031: AB_11124541, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (1.07e-1)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (1.52e-2)" "unprognostic (2.74e-1)" "unprognostic (8.92e-2)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-2)" "unprognostic (3.36e-1)" "unprognostic (2.90e-5)" "unprognostic (9.12e-2)" "unprognostic (6.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.61e-4)" TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 470.9;Extravillous trophoblasts: 342.7;Syncytiotrophoblasts: 889.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Liver - Hepatic stellate cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" TVP23A "FAM18A, YDR084C" ENSG00000166676 "Trans-golgi network vesicle protein 23 homolog A" A6NH52 16 10760919-10818794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 28.0;Granulosa cells: 30.8;Inhibitory neurons: 27.2;Langerhans cells: 61.6;Oligodendrocyte precursor cells: 22.2;Oocytes: 16.9;Sertoli cells: 13.6" "Cancer enhanced" "Detected in some" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060582 Uncertain Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 3 Vesicles "HPA060582: AB_2684326" "unprognostic (6.70e-4)" "unprognostic (1.64e-3)" "unprognostic (2.38e-2)" "unprognostic (8.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.39e-5)" "unprognostic (4.96e-2)" "unprognostic (4.68e-2)" "unprognostic (4.42e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-2)" "unprognostic (2.42e-1)" "unprognostic (8.78e-7)" "unprognostic (1.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.87e-2)" "unprognostic (2.87e-4)" TVP23B "CGI-148, FAM18B, FAM18B1, YDR084C" ENSG00000171928 "Trans-golgi network vesicle protein 23 homolog B" Q9NYZ1 17 18781111-18806714 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 62.9;Squamous epithelial cells: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 17 "Golgi apparatus" "HPA019585: AB_1848385, HPA065603: AB_2685517" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (9.32e-3)" "unprognostic (1.13e-2)" "unprognostic (8.51e-2)" "unprognostic (2.37e-1)" "unprognostic (3.32e-2)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (3.54e-1)" "unprognostic (5.27e-1)" "unprognostic (7.78e-2)" "unprognostic (8.55e-2)" TVP23C "FAM18B2, MGC8763" ENSG00000175106 "Trans-golgi network vesicle protein 23 homolog C" Q96ET8 17 15502264-15563595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Golgi apparatus" "HPA019585: AB_1848385, HPA065603: AB_2685517" "unprognostic (2.87e-3)" "unprognostic (5.35e-3)" "unprognostic (1.01e-1)" "unprognostic (8.39e-3)" "unprognostic (1.33e-3)" "unprognostic (3.00e-1)" "unprognostic (6.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.01e-1)" "unprognostic (1.10e-3)" "unprognostic (3.43e-1)" "unprognostic (8.09e-5)" "unprognostic (2.42e-2)" "unprognostic (1.61e-1)" "unprognostic (3.50e-1)" "unprognostic (2.45e-2)" TVP23C-CDRT4 FAM18B2-CDRT4 ENSG00000259024 "TVP23C-CDRT4 readthrough" 17 15436021-15563561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 12 "Astrocytes: 15.2;Excitatory neurons: 17.4;Inhibitory neurons: 22.8;Microglial cells: 20.6;Oligodendrocyte precursor cells: 27.4;Oligodendrocytes: 27.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 35.1" HPA065603 Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "HPA065603: AB_2685517" "unprognostic (3.95e-3)" "unprognostic (1.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.59e-1)" "unprognostic (8.67e-3)" "unprognostic (9.05e-2)" "unprognostic (4.71e-2)" "unprognostic (9.40e-3)" "unprognostic (3.49e-2)" "unprognostic (1.07e-1)" "unprognostic (2.24e-1)" "unprognostic (4.40e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.57e-1)" "unprognostic (2.07e-1)" "unprognostic (2.08e-1)" TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Plasma cells: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 119.2;Myeloma: 175.3" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" 7 "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" TXNDC15 "2310047H23Rik, C5orf14, FLJ22625" ENSG00000113621 "Thioredoxin domain containing 15" Q96J42 5 134874371-134901635 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015483 Approved Approved "Golgi apparatus" NA NA 49000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "HPA015483: AB_1845722" "unprognostic (1.56e-1)" "unprognostic (1.22e-2)" "unprognostic (2.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.68e-2)" "unprognostic (9.71e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.36e-1)" "unprognostic (4.37e-1)" "unprognostic (1.41e-3)" "unprognostic (1.50e-1)" TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 122.7;Inhibitory neurons: 84.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" "No annotated function" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 30.7" "Cell type enriched" "Detected in some" 8 "Melanocytes: 295.5" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 145 "skin cancer: 268.0" "Skin - Melanocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 82: Skin - Keratinization" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 45.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 41.0;Granulosa cells: 64.3;Leydig cells: 44.2;Oligodendrocytes: 43.6;Ovarian stromal cells: 54.4;Peritubular cells: 45.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Kidney - Podocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 66: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 13 "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 589.1;lymphoid tissue: 413.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 5142.2;Kupffer cells: 3057.7;Langerhans cells: 2435.1;Macrophages: 2419.9;monocytes: 3438.0;NK-cells: 1312.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6461.2" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 26 "Leukemia: 111.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 5 "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 69.4;heart muscle: 57.8;skin 1: 141.3" "Cell type enriched" "Detected in some" 34 "Melanocytes: 3621.2" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Region enriched" "Detected in many" 16 "choroid plexus: 104.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "skin cancer: 576.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Melanocytes" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 13: Skin - Cornification" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 2 Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239514 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.8;Oligodendrocytes: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA015535: AB_1856487, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (1.53e-1)" "unprognostic (5.49e-3)" "unprognostic (1.62e-1)" "unprognostic (3.05e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-1)" "unprognostic (1.83e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.86e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-2)" "unprognostic (4.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (1.79e-2)" TYW1B "LINC00069, MGC87315, NCRNA00069, RSAFD2" ENSG00000277149 "TRNA-yW synthesizing protein 1 homolog B" Q6NUM6 7 72558744-72828200 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.8;Inhibitory neurons: 26.6;Oligodendrocyte precursor cells: 21.7;Oligodendrocytes: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Neurons - Neuronal signaling" 1 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: AB_2668852, HPA014118: AB_2668941, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (2.61e-1)" "unprognostic (3.54e-1)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (1.91e-2)" "unprognostic (6.22e-3)" "unprognostic (3.88e-2)" "unprognostic (1.64e-2)" "unprognostic (1.19e-2)" "unprognostic (8.96e-3)" "unprognostic (5.78e-2)" "unprognostic (2.90e-2)" "unprognostic (4.33e-4)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.90e-2)" UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm,Cytosol NA NA 14000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 9 Nucleoplasm Cytosol "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" UBA2 "FLJ13058, HRIHFB2115, SAE2" ENSG00000126261 "Ubiquitin like modifier activating enzyme 2" Q9UBT2 19 34428352-34471251 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA041436 Supported Supported Nucleoplasm NA NA 130000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 48: Smooth muscle cells - Signal transduction" 3 Nucleoplasm "HPA041436: AB_2677479" "unprognostic (2.37e-1)" "unprognostic (3.17e-1)" "unprognostic (2.13e-2)" "unprognostic (1.36e-3)" "unprognostic (6.39e-3)" "unprognostic (8.72e-3)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.96e-2)" "unprognostic (2.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.58e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (2.11e-2)" "unprognostic (2.00e-1)" "unprognostic (1.88e-1)" UBA5 "FLJ23251, UBE1DC1" ENSG00000081307 "Ubiquitin like modifier activating enzyme 5" Q9GZZ9 3 132654446-132679794 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 423.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017235, HPA076042" Supported Enhanced Vesicles,Cytosol NA NA 43000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 36: Late spermatids - Unknown function" 6 Cytosol Vesicles "HPA017235: AB_1858507, HPA076042: " "unprognostic (4.34e-3)" "unprognostic (6.44e-2)" "unprognostic (7.70e-2)" "unprognostic (3.49e-1)" "unprognostic (8.25e-2)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.06e-1)" "unprognostic (3.28e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.84e-2)" "unprognostic (3.56e-1)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 50.7;granulocytes: 47.1;Proximal enterocytes: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.9" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 370000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 57: Platelets - Hemostasis" 2 "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 57: Platelets - Hemostasis" 3 Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352722 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Late spermatids: 1498.7;Plasma cells: 888.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 226.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 34 "CAB073419: , HPA003509: AB_1858531" "unprognostic (1.82e-1)" "unprognostic (3.20e-2)" "unprognostic (1.55e-3)" "prognostic favorable (2.87e-4)" "unprognostic (3.41e-1)" "unprognostic (7.93e-3)" "prognostic unfavorable (6.90e-5)" "unprognostic (1.19e-1)" "unprognostic (9.36e-2)" "prognostic favorable (7.43e-4)" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.11e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (9.38e-2)" UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 7 Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" 33 Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 105.2;Inhibitory neurons: 104.2;Oligodendrocyte precursor cells: 95.7;Oligodendrocytes: 118.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839, HPA046727" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Smooth muscle cells - Signal transduction" 5 Vesicles "Nucleoplasm, Cytosol" "HPA038838: AB_10673120, HPA038839: , HPA046727: " "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564029-42693505 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 133.8;Inhibitory neurons: 136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.7;tongue: 83.7" "Cell type enhanced" "Detected in all" "Astrocytes: 154.2;Excitatory neurons: 294.9;Inhibitory neurons: 289.4;Oligodendrocyte precursor cells: 217.9;Oligodendrocytes: 268.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" UBR4 "KIAA0462, KIAA1307, p600, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 21: Testis - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" 1 Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 993.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 21: Early spermatids - Spermatogenesis" 4 "Endoplasmic reticulum" "HPA036325: AB_10669788" "unprognostic (1.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (1.47e-1)" "unprognostic (1.54e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-1)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (5.14e-3)" UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 120.3" "Cell type enhanced" "Detected in all" "Early spermatids: 134.5;Granulosa cells: 81.3;Late spermatids: 209.4;Ovarian stromal cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" 7 "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" UGCG GCS ENSG00000148154 "UDP-glucose ceramide glucosyltransferase" Q16739 9 111896814-111935369 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 111.7" "Cell type enhanced" "Detected in all" "dendritic cells: 453.5;Glandular and luminal cells: 291.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 21 "plasmacytoid DC: 109.8" "Lineage enriched" "Detected in all" 21 "dendritic cells: 109.8" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024124 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA024124: AB_1858595" "unprognostic (1.22e-2)" "prognostic favorable (6.62e-4)" "unprognostic (5.39e-2)" "prognostic favorable (4.44e-5)" "unprognostic (1.53e-2)" "unprognostic (9.70e-2)" "unprognostic (3.20e-2)" "unprognostic (2.04e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (3.22e-1)" "unprognostic (9.84e-3)" "unprognostic (2.24e-2)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (3.77e-2)" UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 68.7;liver: 139.1;urinary bladder: 85.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.4;Early spermatids: 26.4;Gastric mucus-secreting cells: 14.1;Late spermatids: 35.3;Squamous epithelial cells: 16.1" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 261.8" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Late spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 6.6;kidney: 2.2;liver: 3.5;pituitary gland: 5.4" "Cell type enhanced" "Detected in some" "Club cells: 1.1;Collecting duct cells: 1.9;Proximal tubular cells: 4.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Region enriched" "Detected in single" 15 "choroid plexus: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lung cancer: 1.0;Myeloma: 1.4" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" UGT2A2 ENSG00000271271 "UDP glucuronosyltransferase family 2 member A2" P0DTE5 4 69588417-69639642 "Enzymes, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 6.0;liver: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "HPA045108: AB_2679218" UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 30.5;kidney: 20.4;liver: 12.9;pancreas: 15.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 89.7;Distal enterocytes: 104.0;Enteroendocrine cells: 45.6;Hepatocytes: 51.0;Paneth cells: 57.8;Proximal enterocytes: 229.6;Proximal tubular cells: 113.3;Undifferentiated cells: 81.4" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Supported NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815994-68832023 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 150 "liver: 226.6" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 271.2" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" HPA045108 Uncertain NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA045108: AB_2679218" "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214748 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 233.7" "Group enriched" "Detected in some" 4 "Breast glandular cells: 7.7;Cholangiocytes: 7.6;Melanocytes: 5.2" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 4.7;eosinophil: 3.6" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.7" "Group enriched" "Detected in some" 14 "liver cancer: 6.5;prostate cancer: 16.3" "Liver - Hepatocytes" HPA045108 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 73: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 1 "HPA045108: AB_2679218" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646597-68670652 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "gallbladder: 75.1;liver: 282.4" "Group enriched" "Detected in some" 6 "Cholangiocytes: 213.7;Hepatocytes: 139.0" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "prostate cancer: 9.8" "Colon - Colon enterocytes, Liver - Hepatocytes" HPA045108 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "HPA045108: AB_2679218" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favorable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favorable (4.50e-4)" UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537173-68576413 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 368.4;liver: 107.8" "Group enriched" "Detected in some" 4 "Distal enterocytes: 173.2;Enteroendocrine cells: 123.6;Undifferentiated cells: 82.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "memory B-cell: 4.0;naive B-cell: 15.2" "Lineage enriched" "Detected in single" 61 "B-cells: 15.2" "Group enriched" "Detected in some" 4 "lymphoma: 5.2;Myeloma: 7.1;prostate cancer: 12.6" "Colon - Colon enterocytes" HPA045108 Supported NA NA "Cluster 34: B-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" "HPA045108: AB_2679218" "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "breast: 193.8" "Cell type enriched" "Detected in single" 32 "Cholangiocytes: 11.4" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enriched" "Detected in single" 9 "prostate cancer: 4.1" HPA045108 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 73: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1234.7" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 806.8" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "liver cancer: 32.2" "Liver - Hepatocytes" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1252.4;liver: 1563.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 122.5;Glandular and luminal cells: 226.9;Hepatocytes: 508.9;Proximal tubular cells: 956.8" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 86.1;Uterine cancer: 39.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" HPA045108 Uncertain NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 49.2;liver: 56.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 29.2;Early spermatids: 164.8;Hepatocytes: 63.9;Late spermatids: 24.4;Proximal tubular cells: 69.3" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 2.5;Sarcoma: 1.4" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.4;lymphoid tissue: 14.3;skin 1: 10.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Early spermatids: 4.2;Late spermatids: 8.6;Proximal tubular cells: 2.0" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 178.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 227.2" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 764.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 13 "B-cells: 10.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 11: Neuronal - Sensory perception" "Cluster 51: Oligodendrocytes - Unknown function" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" ULBP1 RAET1I ENSG00000111981 "UL16 binding protein 1" Q9BZM6 6 149963943-149973715 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.6;lung: 1.6;testis: 3.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 3.9;Granulosa cells: 1.5;monocytes: 2.0;Sertoli cells: 2.7;Squamous epithelial cells: 2.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA007547, HPA071005" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 80: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA007547: AB_1079430, HPA071005: AB_2686332" "unprognostic (8.94e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-2)" "unprognostic (2.33e-2)" "unprognostic (3.28e-4)" "unprognostic (6.69e-3)" "unprognostic (5.27e-2)" "unprognostic (2.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.57e-12)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-2)" ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5.9" "Cell type enhanced" "Detected in many" "Adipocytes: 25.5;Basal respiratory cells: 16.4;Late spermatids: 10.8;Squamous epithelial cells: 12.0;T-cells: 9.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.7" "Cell type enhanced" "Detected in many" "Early spermatids: 359.7;Excitatory neurons: 104.8;Inhibitory neurons: 94.9;Late spermatids: 425.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: Endometrial stromal cells - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 689 "kidney: 2197.0" "Group enriched" "Detected in some" 164 "Collecting duct cells: 204.2;Distal tubular cells: 405.7" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" Immunity NA NA 55000000 66000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" UMODL1 ENSG00000177398 "Uromodulin like 1" Q5DID0 21 42062959-42143453 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "fallopian tube: 1.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.4;Early spermatids: 4.5;Intestinal goblet cells: 1.0;Late spermatids: 2.4;Oocytes: 1.5;Spermatocytes: 1.5" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.9" "Region enhanced" "Detected in some" "cerebral cortex: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA067245 Uncertain NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Ciliated cells - Cilium assembly" "HPA067245: AB_2685810" "unprognostic (4.70e-3)" "unprognostic (3.75e-5)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (4.92e-2)" "unprognostic (1.32e-2)" "unprognostic (2.72e-7)" "unprognostic (2.38e-1)" "unprognostic (9.47e-2)" "unprognostic (2.63e-2)" "unprognostic (3.82e-1)" "unprognostic (9.24e-3)" "unprognostic (4.37e-2)" "unprognostic (1.78e-1)" "unprognostic (4.02e-4)" "unprognostic (2.68e-1)" UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 32: Smooth muscle cells - Muscle contraction" 6 "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 205.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 29 "HPA027009: AB_1858620" "prognostic unfavorable (4.79e-4)" "unprognostic (3.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (5.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "unprognostic (7.12e-3)" "unprognostic (4.82e-3)" UNC5A "KIAA1976, UNC5H1" ENSG00000113763 "Unc-5 netrin receptor A" Q6ZN44 5 176810519-176880898 "Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 63.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 52.6;Horizontal cells: 19.5;Inhibitory neurons: 18.5;Lymphatic endothelial cells: 9.0;Muller glia cells: 9.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 18.5" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071450 Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA071450: AB_2686397" "unprognostic (5.95e-2)" "unprognostic (1.15e-1)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.23e-4)" "unprognostic (5.26e-2)" "unprognostic (2.23e-1)" "unprognostic (6.66e-3)" "unprognostic (5.06e-3)" "unprognostic (3.52e-1)" "unprognostic (1.36e-1)" "unprognostic (5.07e-1)" "unprognostic (9.95e-2)" "unprognostic (3.77e-5)" "unprognostic (6.39e-2)" "unprognostic (2.89e-1)" "unprognostic (2.27e-1)" "unprognostic (5.17e-2)" UNC5B "p53RDL1, UNC5H2" ENSG00000107731 "Unc-5 netrin receptor B" Q8IZJ1 10 71212570-71302864 "Plasma proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 76.2;Horizontal cells: 74.3;Lymphatic endothelial cells: 45.8;Muller glia cells: 47.4;Oligodendrocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076687 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA076687: " "unprognostic (3.98e-2)" "unprognostic (3.14e-2)" "unprognostic (9.28e-2)" "unprognostic (2.71e-1)" "unprognostic (5.64e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.01e-5)" "unprognostic (8.82e-3)" "unprognostic (6.79e-3)" "prognostic unfavorable (3.80e-5)" "unprognostic (7.70e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.17e-2)" "unprognostic (4.62e-2)" "unprognostic (9.89e-3)" "unprognostic (2.25e-1)" UNC5D "KIAA1777, Unc5h4" ENSG00000156687 "Unc-5 netrin receptor D" Q6UXZ4 8 35235475-35796550 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 5.8;prostate: 4.7;retina: 4.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 618.1;Inhibitory neurons: 737.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4;renal cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.6;thyroid cancer: 3.0" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042940 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" "HPA042940: AB_10959525" "unprognostic (7.88e-2)" "unprognostic (1.28e-1)" "unprognostic (1.41e-2)" "unprognostic (2.29e-1)" "unprognostic (7.60e-2)" "unprognostic (1.87e-1)" "unprognostic (8.47e-2)" "unprognostic (3.82e-2)" "unprognostic (2.04e-1)" "unprognostic (4.13e-2)" "unprognostic (1.99e-1)" "unprognostic (4.48e-8)" "unprognostic (1.34e-1)" "unprognostic (9.15e-2)" "unprognostic (4.28e-1)" UNC79 KIAA1409 ENSG00000133958 "Unc-79 homolog, NALCN channel complex subunit" Q9P2D8 14 93333219-93707876 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.1;pituitary gland: 11.4;retina: 5.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 506.3;Inhibitory neurons: 444.0;Oligodendrocyte precursor cells: 253.8;Oligodendrocytes: 188.5" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.1;thyroid cancer: 2.5" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071881 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA071881: AB_2732189" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.70e-2)" "unprognostic (6.91e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-2)" "unprognostic (2.99e-2)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.73e-3)" "unprognostic (8.03e-3)" "unprognostic (2.87e-1)" "unprognostic (3.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.57e-2)" "unprognostic (3.03e-2)" "unprognostic (7.47e-2)" UNC93A "dJ366N23.1, dJ366N23.2" ENSG00000112494 "Unc-93 homolog A" Q86WB7 6 167271169-167316014 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "esophagus: 4.9;intestine: 9.3;liver: 13.6;skin 1: 18.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.7;Hepatocytes: 6.2;Oocytes: 30.1;Proximal enterocytes: 3.4" "Cancer enhanced" "Detected in many" "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.8;Gastric cancer: 7.1;liver cancer: 3.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA035729 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 44: Oocytes - Unknown function" "HPA035729: AB_10696508" "unprognostic (2.49e-1)" "unprognostic (2.67e-1)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.26e-1)" "unprognostic (2.32e-1)" "unprognostic (2.10e-1)" "unprognostic (3.32e-3)" "unprognostic (2.99e-2)" "unprognostic (5.97e-3)" "unprognostic (1.85e-1)" "unprognostic (4.92e-2)" UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 74.8" "Cell type enhanced" "Detected in many" "dendritic cells: 145.1;Hofbauer cells: 96.9;Macrophages: 82.9;monocytes: 132.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 18.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 24 Nucleoplasm "HPA038716: AB_2676169, HPA038717: AB_10674836, HPA042803: AB_2678176" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (7.66e-2)" "unprognostic (1.29e-2)" "unprognostic (9.36e-2)" "unprognostic (5.82e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.76e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.73e-2)" "unprognostic (1.85e-2)" "unprognostic (7.05e-3)" "unprognostic (5.23e-3)" UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109126725 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 154.4;Spermatogonia: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011605, HPA071225" Uncertain Supported Nucleoplasm,Mitochondria NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 Nucleoplasm Mitochondria "CAB011605: AB_778737, HPA071225: " "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" UPK1A TSPAN21 ENSG00000105668 "Uroplakin 1A" O00322 19 35666517-35678481 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 125.8" "Cell type enriched" "Detected in some" 5 "Club cells: 68.7" "Cancer enriched" "Detected in many" 41 "urothelial cancer: 148.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bladder cancer: 20.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049879 Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "HPA049879: AB_2680929" "unprognostic (3.29e-1)" "unprognostic (1.78e-1)" "unprognostic (1.19e-3)" "unprognostic (3.40e-4)" "unprognostic (4.05e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-2)" "unprognostic (3.11e-3)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (2.34e-1)" "unprognostic (2.48e-9)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (2.45e-2)" "unprognostic (1.72e-1)" UPK1B "TSPAN20, UPK1" ENSG00000114638 "Uroplakin 1B" O75841 3 119173517-119205143 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 32.9;urinary bladder: 85.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 32.4;Club cells: 157.8;Glandular and luminal cells: 82.2;Ionocytes: 34.6;Mesothelial cells: 123.1" "Cancer enriched" "Detected in many" 4 "urothelial cancer: 147.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 251.9" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA031799, HPA031800" Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 41 "HPA031799: AB_10671579, HPA031800: AB_10671580" "unprognostic (1.20e-2)" "unprognostic (7.18e-2)" "prognostic favorable (3.87e-5)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (8.77e-3)" "unprognostic (3.67e-1)" "unprognostic (2.71e-1)" "unprognostic (3.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.68e-1)" "unprognostic (6.76e-2)" "unprognostic (2.95e-2)" UPK2 "MGC138598, UP2, UPII" ENSG00000110375 "Uroplakin 2" O00526 11 118925164-118958559 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "urinary bladder: 67.9" "Group enriched" "Detected in some" 9 "Club cells: 24.8;Cytotrophoblasts: 10.4;Syncytiotrophoblasts: 11.4" "Cancer enriched" "Detected in many" 72 "urothelial cancer: 339.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 35.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043312, HPA061106" Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 20 "HPA043312: AB_2678420, HPA061106: AB_2684429" "unprognostic (6.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (3.97e-2)" "unprognostic (1.21e-1)" "unprognostic (4.12e-4)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (3.13e-3)" "unprognostic (1.37e-1)" "unprognostic (1.05e-3)" "unprognostic (6.35e-3)" "prognostic unfavorable (7.30e-7)" "unprognostic (6.69e-2)" "unprognostic (7.45e-2)" "unprognostic (2.98e-1)" "unprognostic (1.00e-1)" UPK3A UPK3 ENSG00000100373 "Uroplakin 3A" O75631 22 45284949-45295874 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "prostate: 20.6;skeletal muscle: 33.8;urinary bladder: 46.4" "Cell type enhanced" "Detected in some" "Club cells: 38.4;dendritic cells: 12.1;Prostatic glandular cells: 61.7;Proximal enterocytes: 27.5;Schwann cells: 15.5" "Group enriched" "Detected in many" 6 "prostate cancer: 35.3;urothelial cancer: 78.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "myeloid DC: 86.7" "Group enriched" "Detected in many" 16 "dendritic cells: 86.7;monocytes: 32.2" "Cancer enhanced" "Detected in some" "breast cancer: 7.8;colorectal cancer: 7.4;prostate cancer: 6.3" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018407, HPA018415" Enhanced Uncertain "Nuclear membrane,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 2 "Nuclear membrane" "Nuclear bodies" "HPA018407: AB_1858641, HPA018415: AB_1858640" "unprognostic (1.27e-2)" "unprognostic (3.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (9.42e-2)" "unprognostic (3.98e-5)" "unprognostic (1.69e-2)" "unprognostic (4.82e-4)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-5)" "unprognostic (2.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (6.05e-3)" UPK3B "FLJ32198, MGC10902, p35, UPIIIb" ENSG00000243566 "Uroplakin 3B" Q9BT76 7 76510525-76516522 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 116.7;esophagus: 63.0;lung: 48.4;urinary bladder: 40.9" "Cell type enriched" "Detected in some" 12 "Mesothelial cells: 1046.6" "Group enriched" "Detected in many" 12 "ovarian cancer: 64.6;urothelial cancer: 78.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 49.5" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA010506 Approved NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" "HPA010506: AB_1080479" "unprognostic (8.33e-2)" "unprognostic (1.30e-1)" "unprognostic (3.62e-3)" "unprognostic (2.26e-3)" "unprognostic (7.87e-2)" "unprognostic (8.60e-2)" "unprognostic (1.12e-1)" "unprognostic (2.63e-1)" "unprognostic (4.03e-1)" "unprognostic (5.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.06e-2)" "unprognostic (8.37e-9)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-1)" "unprognostic (6.34e-2)" UPK3BL1 "UPK3BL, UPLP" ENSG00000267368 "Uroplakin 3B like 1" B0FP48 7 102637025-102642791 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 265.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3.9;Enteroendocrine cells: 3.9;Intestinal goblet cells: 5.4;Paneth cells: 5.5;Undifferentiated cells: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA011403 Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 61: BICR 18 - Protein kinases" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA011403: AB_2668503" "unprognostic (4.63e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-2)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (6.19e-3)" "unprognostic (3.35e-1)" "unprognostic (2.88e-1)" "unprognostic (9.39e-3)" "unprognostic (4.00e-1)" "unprognostic (8.11e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.93e-2)" UPK3BL2 ENSG00000284981 "Uroplakin 3B like 2" E5RIL1 7 102537919-102543696 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 24.4;lymphoid tissue: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 2.7;cervical cancer: 3.7;Esophageal cancer: 8.9;head and neck cancer: 6.8" HPA011403 Approved NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 73: B-cells - B-cell function" "HPA011403: AB_2668503" UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.5;Inhibitory neurons: 66.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 8: Neurons - Neuronal signaling" 3 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 205.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" URGCP "DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4" ENSG00000106608 "Upregulator of cell proliferation" Q8TCY9 7 43875894-43926411 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019879, HPA020134, HPA029468" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA019879: AB_1858651, HPA020134: AB_1858652, HPA029468: AB_10601831" "unprognostic (5.66e-2)" "unprognostic (1.10e-3)" "unprognostic (1.18e-1)" "unprognostic (2.75e-1)" "unprognostic (2.21e-3)" "unprognostic (2.42e-2)" "unprognostic (3.74e-2)" "unprognostic (1.26e-1)" "unprognostic (3.79e-1)" "unprognostic (2.21e-1)" "unprognostic (3.23e-3)" "unprognostic (3.71e-1)" "prognostic favorable (1.90e-4)" "unprognostic (1.56e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (1.69e-3)" USE1 "D12, MDS032, p31, SLT1" ENSG00000053501 "Unconventional SNARE in the ER 1" Q9NZ43 19 17215346-17219829 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026851, HPA047562" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 15: Non-specific - Mixed function" 17 "HPA026851: AB_10602903, HPA047562: AB_2680089" "unprognostic (3.03e-3)" "unprognostic (2.61e-3)" "unprognostic (2.24e-2)" "unprognostic (3.09e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.04e-2)" "unprognostic (4.24e-1)" "unprognostic (2.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.14e-2)" "unprognostic (3.23e-1)" "unprognostic (6.61e-2)" "unprognostic (1.31e-2)" USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088023 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 53.0;Oligodendrocytes: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Late spermatids - Unknown function" 1 "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favorable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 318.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)" VAMP1 "SYB1, VAMP-1" ENSG00000139190 "Vesicle associated membrane protein 1" P23763 12 6462237-6470677 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 133.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 21.9;Inhibitory neurons: 24.0;Oligodendrocytes: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002779, CAB016119, CAB079000" Approved Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "CAB002779: , CAB016119: AB_628309, CAB079000: " "unprognostic (2.33e-1)" "unprognostic (6.72e-3)" "prognostic unfavorable (6.37e-5)" "unprognostic (8.09e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.22e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.40e-3)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.04e-11)" "unprognostic (1.47e-2)" "unprognostic (5.99e-2)" "unprognostic (1.62e-1)" "unprognostic (3.65e-2)" VAMP2 "SYB2, VAMP-2" ENSG00000220205 "Vesicle associated membrane protein 2" P63027 17 8159149-8163546 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 470.8" "Cell type enhanced" "Detected in all" "Bipolar cells: 1035.5;Cone photoreceptor cells: 1126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB078785 Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 25: Bipolar cells - Visual perception" 25 "CAB078785: " "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (1.58e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (7.28e-2)" "unprognostic (5.15e-2)" "unprognostic (1.55e-1)" "prognostic favorable (3.83e-6)" "unprognostic (8.27e-2)" "prognostic favorable (9.76e-8)" "unprognostic (1.21e-2)" "unprognostic (7.00e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" VAMP4 ENSG00000117533 "Vesicle associated membrane protein 4" O75379 1 171700160-171742074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050418 Enhanced Approved "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 35 "Golgi apparatus" "HPA050418: AB_2681121" "unprognostic (9.38e-2)" "unprognostic (7.09e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.66e-2)" "unprognostic (6.97e-2)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (5.10e-2)" "unprognostic (3.14e-2)" "unprognostic (2.87e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (5.43e-6)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" "unprognostic (3.16e-2)" "unprognostic (1.15e-1)" VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 496.6;Endothelial cells: 348.7;Melanocytes: 324.7;monocytes: 306.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 58 "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" VAMP7 "SYBL1, TI-VAMP, VAMP-7" ENSG00000124333 "Vesicle associated membrane protein 7" P51809 X 155881345-155943769 "Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036733 Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Liver - Plasma proteins" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" 3 Vesicles "HPA036733: AB_10672228" "unprognostic (7.54e-3)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (6.15e-3)" "unprognostic (2.70e-2)" "unprognostic (5.77e-2)" "unprognostic (7.95e-2)" "unprognostic (7.18e-2)" "unprognostic (3.38e-3)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.29e-1)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (2.97e-1)" VAMP8 "EDB, VAMP-8" ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1201.5;Proximal enterocytes: 1181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" VANGL2 "KIAA1215, LPP1, LTAP, MGC119403, MGC119404, STB1, STBM, STBM1" ENSG00000162738 "VANGL planar cell polarity protein 2" Q9ULK5 1 160400564-160428670 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 36.6" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 36.1;testis cancer: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027043 Uncertain NA NA "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "HPA027043: AB_10601709" "unprognostic (4.32e-3)" "unprognostic (1.86e-1)" "unprognostic (1.59e-2)" "unprognostic (1.07e-3)" "unprognostic (3.05e-1)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (1.84e-3)" "unprognostic (9.83e-2)" "unprognostic (3.84e-1)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-2)" VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 580000 "Cluster 29: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Mixed function" 37 "Endoplasmic reticulum" "HPA009174: AB_1080549" "unprognostic (4.03e-2)" "unprognostic (7.47e-2)" "unprognostic (9.36e-2)" "unprognostic (5.20e-2)" "unprognostic (2.00e-1)" "unprognostic (2.99e-2)" "unprognostic (4.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.39e-2)" "unprognostic (6.80e-3)" "unprognostic (2.99e-2)" "unprognostic (8.11e-2)" "prognostic favorable (5.72e-7)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (5.77e-2)" VAPB "ALS8, VAP-B, VAP-C" ENSG00000124164 "VAMP associated protein B and C" O95292 20 58389229-58451101 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013144, CAB013722" Supported Enhanced "Endoplasmic reticulum" NA NA 240000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 32: Smooth muscle cells - Muscle contraction" 33 "Endoplasmic reticulum" "CAB013722: , HPA013144: AB_1858717" "unprognostic (3.28e-3)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (9.36e-2)" "unprognostic (3.15e-2)" "unprognostic (4.76e-3)" "unprognostic (2.80e-1)" "unprognostic (4.47e-2)" "unprognostic (8.06e-3)" "unprognostic (3.11e-2)" "unprognostic (2.99e-1)" "prognostic favorable (1.08e-8)" "unprognostic (1.05e-1)" "unprognostic (5.31e-1)" "unprognostic (6.34e-3)" "unprognostic (2.99e-2)" VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 56.4;Fibroblasts: 80.9;Peritubular cells: 60.5;Secretory cells: 53.6;Sertoli cells: 65.3;Smooth muscle cells: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" "No annotated function" NA Yes 2000000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 42 Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" VCAM1 CD106 ENSG00000162692 "Vascular cell adhesion molecule 1" P19320 1 100719742-100739045 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 379.4" "Cell type enhanced" "Detected in many" "Ductal cells: 149.9;Endothelial cells: 74.9;Kupffer cells: 376.7;Proximal tubular cells: 167.1" "Cancer enriched" "Detected in all" 8 "renal cancer: 89.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 34.3;Kidney cancer: 63.3;thyroid cancer: 43.7" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000154, HPA034796, HPA069867" Enhanced Approved "Cell Junctions" NA NA 624000000 1300000000 "Cluster 47: Spleen - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "Cell Junctions" "CAB000154: , HPA034796: AB_2674333, HPA069867: AB_2686215" "unprognostic (2.96e-1)" "prognostic favorable (3.82e-4)" "unprognostic (1.31e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.19e-5)" "unprognostic (1.60e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.95e-2)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.55e-2)" VEZT DKFZP761C241 ENSG00000028203 "Vezatin, adherens junctions transmembrane protein" Q9HBM0 12 95217746-95302799 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004811, HPA017066" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA004811: AB_1080563, HPA017066: AB_1858742" "unprognostic (3.91e-1)" "unprognostic (6.34e-3)" "unprognostic (3.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.28e-1)" "unprognostic (9.93e-2)" "unprognostic (4.18e-1)" "unprognostic (1.10e-3)" "unprognostic (3.37e-3)" "prognostic unfavorable (1.93e-5)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.51e-1)" "unprognostic (4.06e-1)" "unprognostic (5.02e-2)" VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 128.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 39.6;Distal enterocytes: 54.6;Intestinal goblet cells: 52.2;Paneth cells: 89.4;Proximal enterocytes: 45.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 4 "amygdala: 6.4;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 65.6;Mesothelial cells: 96.5;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 46.7;Rod photoreceptor cells: 43.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.2;Rhabdoid: 3.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 443.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 767.1;Oocytes: 587.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 12 "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 93.9;Alveolar cells type 2: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 72: Alveolar cells - Lung function" 15 "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 75.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.6;Cone photoreceptor cells: 91.8;Rod photoreceptor cells: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 18: Non-specific - Ribosome" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" VMA21 "MEAX, XMEA" ENSG00000160131 "Vacuolar ATPase assembly factor VMA21" Q3ZAQ7 X 151396515-151409364 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 156.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010972 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" 25 "HPA010972: AB_1853034" "unprognostic (1.17e-1)" "prognostic favorable (2.30e-5)" "unprognostic (6.75e-2)" "unprognostic (9.78e-3)" "unprognostic (6.48e-2)" "unprognostic (4.68e-2)" "unprognostic (1.88e-3)" "unprognostic (4.36e-2)" "unprognostic (5.16e-2)" "unprognostic (1.74e-2)" "unprognostic (2.55e-1)" "unprognostic (8.30e-2)" "unprognostic (7.88e-2)" "unprognostic (4.17e-2)" "unprognostic (3.21e-2)" "unprognostic (3.90e-2)" "unprognostic (2.76e-1)" VMP1 "EPG3, TANGO5, TMEM49" ENSG00000062716 "Vacuole membrane protein 1" Q96GC9 17 59707192-59842255 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Cell adhesion, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 3016.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 3016.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030773, HPA064780" Approved Approved "Nucleoli,Endoplasmic reticulum" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 6 "Endoplasmic reticulum" Nucleoli "HPA030773: AB_10602248, HPA064780: AB_2685348" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.39e-1)" "unprognostic (2.41e-1)" "unprognostic (2.98e-1)" "unprognostic (8.43e-2)" "unprognostic (4.21e-2)" "prognostic unfavorable (2.77e-8)" "unprognostic (1.88e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-3)" VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457140 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.9;retina: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Cone photoreceptor cells: 1.7;dendritic cells: 1.8;Horizontal cells: 4.4;Oligodendrocyte precursor cells: 2.4;Rod photoreceptor cells: 2.5;Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles Nucleoplasm "HPA062209: " "unprognostic (7.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (5.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-2)" "unprognostic (4.59e-5)" VN1R2 V1RL2 ENSG00000196131 "Vomeronasal 1 receptor 2" Q8NFZ6 19 53258292-53261837 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Early spermatids: 13.3;Late spermatids: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044551 Uncertain NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "HPA044551: AB_2678982" "unprognostic (9.54e-2)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" VN1R4 V1RL4 ENSG00000228567 "Vomeronasal 1 receptor 4" Q7Z5H5 19 53266676-53267723 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027018 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA027018: AB_10603142" VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lymphatic endothelial cells: 173.5;Oligodendrocytes: 141.0;Oocytes: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Mitochondria "HPA042969: AB_10794920, HPA053547: AB_2682183" "unprognostic (7.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.22e-3)" "unprognostic (3.57e-2)" "unprognostic (2.06e-1)" "prognostic favorable (1.31e-8)" "unprognostic (1.82e-3)" "unprognostic (8.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.13e-2)" VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 36.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 101.5;Oocytes: 255.9;Spermatocytes: 231.1;Spermatogonia: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 52: Non-specific - Cell proliferation" 12 Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" VRK2 ENSG00000028116 "VRK serine/threonine kinase 2" Q86Y07 2 57907629-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 503.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 51: Oligodendrocytes - Unknown function" 8 "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: AB_2680071" "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 188.6" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 311.9" "Group enriched" "Detected in many" 17 "lung cancer: 8.7;pancreatic cancer: 17.7;stomach cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 13.0" "Lineage enriched" "Detected in many" 5 "T-cells: 13.0" "Cancer enhanced" "Detected in some" "Gastric cancer: 9.2;liver cancer: 16.3;pancreatic cancer: 8.0" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.5;spinal cord: 27.4" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" 4 "Vesicles, Cytosol" "HPA001445: AB_10669749, HPA036310: AB_10670795, HPA036311: AB_10673350" "unprognostic (4.33e-3)" "unprognostic (4.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-1)" "unprognostic (4.80e-2)" "unprognostic (3.25e-2)" "unprognostic (9.79e-2)" "unprognostic (4.58e-1)" "unprognostic (2.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.31e-7)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-3)" VSIG10 ENSG00000176834 "V-set and immunoglobulin domain containing 10" Q8N0Z9 12 118063593-118136026 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062022 Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Cytosol "Centriolar satellite" "HPA062022: AB_2732675" "unprognostic (1.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.05e-1)" "unprognostic (4.62e-3)" "unprognostic (1.09e-1)" "unprognostic (6.42e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.48e-2)" VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342139 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 19.7;esophagus: 60.5;salivary gland: 25.7;vagina: 21.7" "Group enriched" "Detected in many" 4 "Serous glandular cells: 21.3;Suprabasal keratinocytes: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA060453: AB_2684280, HPA066745: AB_2685712" "unprognostic (1.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.98e-3)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.75e-4)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-4)" "unprognostic (1.42e-2)" "unprognostic (8.51e-2)" "unprognostic (7.74e-2)" "unprognostic (5.19e-3)" VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 602.9" "Group enriched" "Detected in many" 4 "Club cells: 178.1;Distal enterocytes: 614.6;Gastric mucus-secreting cells: 612.0;Intestinal goblet cells: 227.6;Paneth cells: 362.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gastric cancer: 19.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 160.9" "Group enriched" "Detected in many" 4 "Hofbauer cells: 875.5;Kupffer cells: 649.1;Macrophages: 406.1" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 26 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 30 "dendritic cells: 17.8;monocytes: 18.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000, HPA072756" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776, HPA072756: " "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" VSIG8 ENSG00000243284 "V-set and immunoglobulin domain containing 8" P0DPA2 1 159854316-159862657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 24.8" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 141.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;head and neck cancer: 1.5" "Kidney - Podocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023219 Uncertain NA NA 650000 "Cluster 13: Skin - Cornification" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA023219: AB_1845635" "unprognostic (8.66e-3)" "unprognostic (2.17e-1)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (4.50e-3)" "unprognostic (1.15e-2)" "unprognostic (9.26e-2)" "unprognostic (6.28e-2)" "unprognostic (1.68e-2)" "unprognostic (2.79e-1)" "unprognostic (2.93e-3)" "unprognostic (9.32e-2)" "unprognostic (7.94e-7)" "unprognostic (1.72e-2)" "unprognostic (4.25e-1)" "unprognostic (1.81e-3)" "unprognostic (1.99e-1)" VSIR "B7-H5, B7H5, C10orf54, Dies1, GI24, PD-1H, SISP1, VISTA" ENSG00000107738 "V-set immunoregulatory receptor" Q9H7M9 10 71747556-71773520 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 80.5;lymphoid tissue: 88.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.9;Extravillous trophoblasts: 337.2;Kupffer cells: 311.5;monocytes: 480.7;Syncytiotrophoblasts: 686.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1008.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" HPA007968 Approved Nucleoplasm NA NA 320000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 24 Nucleoplasm "HPA007968: AB_1845518" "unprognostic (1.19e-1)" "unprognostic (1.76e-3)" "unprognostic (1.64e-1)" "unprognostic (6.67e-2)" "unprognostic (9.29e-2)" "unprognostic (2.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (1.02e-2)" "unprognostic (6.82e-2)" "unprognostic (8.70e-2)" "unprognostic (2.57e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.37e-3)" "unprognostic (3.29e-1)" VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 42.5" "Group enriched" "Detected in some" 4 "Hofbauer cells: 16.9;Late spermatids: 19.9;monocytes: 27.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 66.3;Granulosa cells: 66.1;Late spermatids: 150.8;Ovarian stromal cells: 39.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 8.2" "Breast - Adipocytes (Breast), Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Late spermatids - Unknown function" 8 "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" VSTM5 "C11orf90, LOC387804" ENSG00000214376 "V-set and transmembrane domain containing 5" A8MXK1 11 93818232-93850618 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.6;placenta: 4.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 21.2;Excitatory neurons: 5.0;Gastric mucus-secreting cells: 3.5;Inhibitory neurons: 8.8;Syncytiotrophoblasts: 4.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 4.2" "Kidney - Proximal tubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029525, HPA063591" Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "Endoplasmic reticulum" "HPA029525: AB_10600789, HPA063591: AB_2732704" "unprognostic (1.26e-1)" "unprognostic (4.48e-3)" "unprognostic (2.78e-1)" "unprognostic (1.54e-4)" "unprognostic (2.45e-2)" "unprognostic (9.91e-2)" "unprognostic (8.56e-2)" "unprognostic (1.37e-2)" "unprognostic (1.68e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.53e-2)" "unprognostic (2.37e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 98.1;fallopian tube: 31.4;pancreas: 29.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 59.1;Collecting duct cells: 44.7;Ductal cells: 81.0;Glandular and luminal cells: 79.6;Mucus glandular cells: 62.9;Salivary duct cells: 30.6;Secretory cells: 71.7" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 51.0;ovarian cancer: 27.5;testis cancer: 27.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 73: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 128.2;Excitatory neurons: 236.5;Inhibitory neurons: 191.3;Late spermatids: 100.0;Microglial cells: 187.0;Oligodendrocyte precursor cells: 161.8;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 51: Oligodendrocytes - Unknown function" 1 "Golgi apparatus, Vesicles" "HPA054108: AB_2682382" "unprognostic (9.81e-2)" "unprognostic (6.42e-2)" "unprognostic (4.49e-2)" "unprognostic (1.50e-1)" "unprognostic (1.66e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.50e-5)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic favorable (7.27e-5)" "unprognostic (3.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-3)" "unprognostic (2.61e-1)" VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 483.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" 26 "Golgi apparatus, Vesicles" "HPA044121: AB_2678819, HPA048150: AB_2680288, HPA060118: AB_2684206" "unprognostic (2.26e-1)" "unprognostic (4.83e-2)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.00e-2)" "unprognostic (2.36e-3)" "unprognostic (3.25e-3)" "unprognostic (9.12e-2)" "unprognostic (1.90e-2)" "unprognostic (3.86e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-2)" "prognostic favorable (3.53e-12)" "unprognostic (8.35e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (8.02e-3)" WAC "BM-016, FLJ31290, MGC10753, PRO1741, Wwp4" ENSG00000095787 "WW domain containing adaptor with coiled-coil" Q9BTA9 10 28532493-28623112 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 439.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036528, HPA042609, HPA074604" Approved Enhanced Nucleoplasm NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" 8 Nucleoplasm "HPA036528: AB_10670839, HPA042609: AB_2678076, HPA074604: " "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.80e-1)" "unprognostic (4.53e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (9.27e-6)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (3.60e-1)" "unprognostic (2.07e-1)" "unprognostic (2.90e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (6.63e-2)" "unprognostic (1.36e-1)" WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.8;Gastric mucus-secreting cells: 32.4;Plasma cells: 38.8;Squamous epithelial cells: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057067 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Non-specific - Transcription" 4 Cytosol "HPA057067: AB_2683326" "unprognostic (5.94e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (6.05e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (5.80e-2)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "prognostic favorable (6.83e-4)" "unprognostic (1.17e-2)" "unprognostic (1.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (6.36e-4)" WBP1L "C10orf26, FLJ20154, OPAL1" ENSG00000166272 "WW domain binding protein 1 like" Q9NX94 10 102743948-102834516 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 570.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037635, HPA038371" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 63: Late spermatids - Spermatogenesis" 15 Microtubules Nucleoplasm "HPA037635: AB_10672462, HPA038371: AB_2675980" "unprognostic (3.28e-2)" "unprognostic (6.46e-2)" "unprognostic (1.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (5.35e-3)" "unprognostic (2.73e-2)" "unprognostic (3.33e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.43e-3)" "unprognostic (2.55e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.56e-6)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (4.88e-2)" "unprognostic (1.53e-1)" WDFY4 "C10orf64, Em:AC060234.3, FLJ45748, KIAA1607" ENSG00000128815 "WDFY family member 4" Q6ZS81 10 48684873-48982956 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.6;lymphoid tissue: 27.8" "Cell type enhanced" "Detected in some" "B-cells: 59.1;dendritic cells: 87.6;Early spermatids: 62.1;Microglial cells: 77.8;Schwann cells: 187.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 14.2;myeloid DC: 11.3;naive B-cell: 20.9;neutrophil: 9.8;plasmacytoid DC: 32.1" "Group enriched" "Detected in many" 7 "B-cells: 20.9;dendritic cells: 32.1;granulocytes: 9.8" "Group enriched" "Detected in some" 9 "Leukemia: 13.8;lymphoma: 35.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040634 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm Cytosol "HPA040634: AB_10795491" "unprognostic (6.20e-2)" "unprognostic (6.60e-3)" "unprognostic (1.87e-1)" "unprognostic (3.31e-2)" "unprognostic (1.87e-1)" "unprognostic (9.38e-4)" "unprognostic (9.41e-2)" "unprognostic (3.89e-3)" "unprognostic (2.15e-2)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" "unprognostic (9.64e-2)" "unprognostic (3.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.76e-2)" WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 16.5;Spermatogonia: 17.5" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 52: Non-specific - Cell proliferation" 1 Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" WDR17 ENSG00000150627 "WD repeat domain 17" Q8IZU2 4 176065841-176182818 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.2;pituitary gland: 11.1;retina: 27.7" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Cone photoreceptor cells: 45.9;Excitatory neurons: 215.2;Inhibitory neurons: 122.2;Oligodendrocyte precursor cells: 117.4" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042766, HPA054501" Approved Approved "Nuclear speckles" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Nuclear speckles" "HPA042766: AB_10806372, HPA054501: AB_2732586" "unprognostic (3.41e-4)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-7)" "unprognostic (3.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (8.62e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-3)" "unprognostic (6.04e-4)" "unprognostic (3.66e-4)" "unprognostic (9.25e-3)" "unprognostic (4.63e-2)" "unprognostic (7.32e-3)" "unprognostic (8.24e-3)" WDR33 "FLJ11294, NET14, WDC146" ENSG00000136709 "WD repeat domain 33" Q9C0J8 2 127701027-127811187 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026897, HPA046527" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 1 "Nucleoplasm, Nucleoli fibrillar center" "HPA026897: AB_1858803, HPA046527: AB_2679686" "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.79e-2)" "unprognostic (6.63e-2)" "unprognostic (8.32e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.13e-2)" "unprognostic (5.72e-3)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" "unprognostic (3.64e-1)" "unprognostic (2.04e-1)" "unprognostic (9.85e-2)" "unprognostic (1.03e-2)" WDR83OS "Asterix, C19orf56, PTD008" ENSG00000105583 "WD repeat domain 83 opposite strand" Q9Y284 19 12668073-12669415 "Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 15.9;Oligodendrocytes: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065685 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 1 "Endoplasmic reticulum" "HPA065685: AB_2685531" "unprognostic (1.73e-1)" "unprognostic (5.37e-3)" "unprognostic (1.03e-1)" "unprognostic (4.86e-2)" "unprognostic (1.27e-1)" "unprognostic (3.29e-2)" "unprognostic (7.47e-2)" "prognostic favorable (2.09e-4)" "unprognostic (1.71e-1)" "prognostic favorable (8.84e-4)" "unprognostic (4.17e-3)" "unprognostic (1.09e-1)" "unprognostic (7.87e-3)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 97.1;Extravillous trophoblasts: 130.0;Lymphatic endothelial cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" 315 "HPA029128: AB_10603460" "unprognostic (4.27e-2)" "unprognostic (5.05e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.13e-6)" "unprognostic (7.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-2)" "unprognostic (6.97e-3)" "unprognostic (2.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.36e-3)" "unprognostic (5.33e-3)" "unprognostic (6.20e-2)" "unprognostic (5.02e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (3.64e-2)" WLS "C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP" ENSG00000116729 "Wnt ligand secretion mediator" Q5T9L3 1 68098473-68233120 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 173.3;Glandular and luminal cells: 245.1;Rod photoreceptor cells: 173.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 22.1;neutrophil: 62.1" "Group enriched" "Detected in many" 46 "granulocytes: 62.1;monocytes: 22.1" "Cancer enhanced" "Detected in many" "testis cancer: 329.0" "Adipose visceral - Adipose progenitor cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069520 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Endoplasmic reticulum, Cytosol" "HPA069520: AB_2686144" "prognostic favorable (4.03e-4)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (8.13e-3)" "unprognostic (5.93e-2)" "unprognostic (4.51e-3)" "unprognostic (5.41e-3)" "unprognostic (7.46e-3)" "unprognostic (7.70e-2)" "prognostic favorable (9.43e-4)" "unprognostic (1.34e-1)" "unprognostic (4.82e-2)" "prognostic favorable (3.67e-7)" "unprognostic (4.48e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.51e-4)" WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.8;skin 1: 8.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.8;Basal respiratory cells: 14.8;Basal squamous epithelial cells: 17.1;Collecting duct cells: 21.4;dendritic cells: 36.0;Plasma cells: 24.8;Secretory cells: 12.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.9" "Adipose visceral - Mesothelial cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - T-cells" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in some" "basal ganglia: 3.2" HPA013898 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Plasma cells - Protein processing" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 81.7;Peritubular cells: 190.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 39.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 22.8;Basal respiratory cells: 42.5;Breast glandular cells: 24.0;Breast myoepithelial cells: 26.3;Endometrial stromal cells: 76.1;Suprabasal keratinocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.8" "Lung - Alveolar cells type 2, Pancreas - Alpha cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 1 Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 6 Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" XCR1 "CCXCR1, GPR5" ENSG00000173578 "X-C motif chemokine receptor 1" P46094 3 46016990-46085825 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.5" "Cell type enriched" "Detected in some" 4 "Schwann cells: 32.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "myeloid DC: 2.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013169 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 1 "HPA013169: AB_1846211" "unprognostic (3.49e-3)" "unprognostic (4.23e-3)" "unprognostic (1.15e-2)" "unprognostic (5.91e-3)" "unprognostic (7.91e-2)" "unprognostic (8.53e-6)" "unprognostic (3.89e-6)" "unprognostic (9.27e-3)" "unprognostic (4.41e-3)" "unprognostic (3.40e-3)" "unprognostic (2.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (5.98e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)" XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group antigen, Kell and VPS13A binding protein" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.0;intestine: 11.8;stomach 1: 11.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 25.9;Enteroendocrine cells: 13.7;Erythroid cells: 33.8;Gastric mucus-secreting cells: 17.7;Proximal enterocytes: 19.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in many" "Myeloma: 12.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 22: Eosinophils - Transcription" "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" XKR3 "MGC57211, XTES" ENSG00000172967 "XK related 3" Q5GH77 22 16783412-16825411 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 7.9" "Cell type enriched" "Detected in some" 17 "Early spermatids: 223.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.9" "Group enriched" "Detected in some" 7 "Bladder cancer: 2.0;Myeloma: 7.0" "Testis - Early spermatids, Testis - Late spermatids" "HPA003379, HPA035081" Uncertain NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA003379: AB_10602682, HPA035081: AB_2674451" "unprognostic (4.57e-1)" "unprognostic (3.37e-1)" "unprognostic (3.11e-2)" "unprognostic (3.13e-2)" "unprognostic (5.77e-2)" XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;intestine: 1.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 295.6;Inhibitory neurons: 977.1;Oligodendrocyte precursor cells: 676.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.8" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Vesicles "Nucleoli, Golgi apparatus" "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (7.15e-4)" "unprognostic (1.28e-3)" "unprognostic (6.98e-2)" "unprognostic (5.63e-3)" "unprognostic (7.39e-2)" "unprognostic (5.68e-3)" "unprognostic (6.33e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-3)" "unprognostic (6.63e-2)" "unprognostic (3.46e-4)" "unprognostic (2.08e-2)" "unprognostic (2.39e-2)" "unprognostic (7.36e-2)" "unprognostic (4.96e-2)" XKR6 "C8orf21, C8orf5, C8orf7" ENSG00000171044 "XK related 6" Q5GH73 8 10896045-11201833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 404.8;Inhibitory neurons: 325.4;Microglial cells: 102.0;Oligodendrocyte precursor cells: 272.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024828, HPA064769" Approved "Actin filaments" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" "Actin filaments" "HPA024828: AB_2215165, HPA064769: AB_2732720" "unprognostic (8.63e-3)" "unprognostic (8.45e-2)" "unprognostic (1.50e-1)" "unprognostic (9.92e-6)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (1.18e-1)" "unprognostic (8.75e-3)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-1)" "unprognostic (3.78e-2)" "unprognostic (3.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.29e-3)" XKR7 "C20orf159, dJ310O13.4" ENSG00000260903 "XK related 7" Q5GH72 20 31968151-32003387 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "brain: 14.6;pituitary gland: 4.2;retina: 4.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.5;Collecting duct cells: 1.9;Cone photoreceptor cells: 5.1;Early spermatids: 2.6;Excitatory neurons: 4.3;Horizontal cells: 3.8;Inhibitory neurons: 4.6;Late spermatids: 2.0;Rod photoreceptor cells: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 20.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 4.7;Neuroblastoma: 10.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 12.2" HPA040854 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA040854: AB_10795481" "unprognostic (2.74e-2)" "unprognostic (5.60e-3)" "unprognostic (8.03e-2)" "unprognostic (3.74e-7)" "unprognostic (4.29e-2)" "unprognostic (9.34e-2)" "unprognostic (1.45e-1)" "unprognostic (2.69e-2)" "unprognostic (4.47e-2)" "unprognostic (2.68e-3)" "unprognostic (2.12e-1)" "unprognostic (1.26e-3)" "unprognostic (3.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-5)" "unprognostic (1.99e-1)" XKR8 FLJ10307 ENSG00000158156 "XK related 8" Q9H6D3 1 27959588-27968093 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "eosinophil: 203.2;neutrophil: 102.0" "Lineage enriched" "Detected in all" 13 "granulocytes: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049984, HPA053529" Uncertain Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "HPA049984: AB_2680982, HPA053529: AB_2682179" "prognostic favorable (8.63e-4)" "unprognostic (2.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-3)" "unprognostic (1.97e-2)" "unprognostic (1.38e-2)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (7.87e-2)" "unprognostic (8.41e-2)" "unprognostic (1.83e-3)" "unprognostic (6.29e-2)" "unprognostic (8.55e-2)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-2)" XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2;testis: 7.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.6;Inhibitory neurons: 17.1;Oligodendrocytes: 21.3;Spermatocytes: 79.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 31: Spermatocytes - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" XPO7 "EXP7, KIAA0745, RANBP16" ENSG00000130227 "Exportin 7" Q9UIA9 8 21919662-22006585 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043727, HPA048153" Uncertain NA NA 53000 "Cluster 25: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 1: Erythroid cells - Oxygen transport" 2 "HPA043727: AB_2678638, HPA048153: AB_2680289" "unprognostic (6.30e-2)" "unprognostic (1.95e-2)" "prognostic favorable (2.29e-4)" "unprognostic (6.61e-3)" "unprognostic (1.81e-1)" "unprognostic (1.33e-2)" "unprognostic (1.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.18e-1)" "unprognostic (6.81e-3)" "unprognostic (9.66e-2)" "unprognostic (3.69e-2)" "unprognostic (2.76e-2)" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" XPR1 "SLC53A1, SYG1, X3" ENSG00000143324 "Xenotropic and polytropic retrovirus receptor 1" Q9UBH6 1 180632022-180890279 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.7;Excitatory neurons: 114.1;Inhibitory neurons: 98.4;Microglial cells: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016557 Supported NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "HPA016557: AB_2669382" "unprognostic (2.65e-1)" "unprognostic (2.68e-2)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.86e-1)" "unprognostic (1.30e-3)" "prognostic unfavorable (3.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.59e-1)" "unprognostic (3.78e-2)" "unprognostic (4.72e-2)" "unprognostic (6.44e-2)" "unprognostic (8.82e-2)" "unprognostic (7.04e-2)" "unprognostic (1.38e-1)" "unprognostic (2.59e-1)" "unprognostic (8.44e-2)" YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 66 "Golgi apparatus, Vesicles" "HPA014840: AB_2217189, HPA076194: " "unprognostic (9.35e-2)" "unprognostic (7.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (4.38e-3)" "unprognostic (2.25e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (6.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.03e-1)" "unprognostic (2.64e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (8.70e-4)" YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Approved "Golgi apparatus,Vesicles" NA NA 37000 "Cluster 29: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 Vesicles "Golgi apparatus" "HPA039328: AB_2676445, HPA055257: AB_2682762, HPA062675: AB_2684830" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.53e-5)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (5.53e-2)" "prognostic favorable (1.88e-4)" "unprognostic (4.57e-2)" "unprognostic (2.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (3.94e-3)" YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 79.9;Syncytiotrophoblasts: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 30 "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" YIPF2 "FinGER2, MGC3262" ENSG00000130733 "Yip1 domain family member 2" Q9BWQ6 19 10922185-10928681 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.3;Syncytiotrophoblasts: 195.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019902 Approved Approved "Golgi apparatus,Mitochondria" No No "Cluster 29: Non-specific - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 19 "Golgi apparatus, Mitochondria" "HPA019902: AB_1858925" "unprognostic (1.27e-1)" "unprognostic (8.56e-2)" "unprognostic (2.90e-3)" "unprognostic (8.38e-2)" "unprognostic (3.66e-1)" "unprognostic (3.96e-1)" "unprognostic (1.93e-1)" "unprognostic (7.65e-2)" "unprognostic (4.30e-2)" "unprognostic (5.62e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.92e-2)" "unprognostic (5.99e-2)" "unprognostic (2.00e-2)" YIPF3 "C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1" ENSG00000137207 "Yip1 domain family member 3" Q9GZM5 6 43511832-43516985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014859, HPA063699" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 28: Non-specific - Nuclear processes" "Cluster 77: Plasma cells - Protein processing" 13 "Golgi apparatus" Nucleoplasm "HPA014859: AB_1845729, HPA063699: AB_2685095" "unprognostic (2.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (4.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.15e-3)" "unprognostic (3.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-2)" "unprognostic (3.55e-1)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 237.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Breast glandular cells - Lactation" 28 "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" YIPF6 "FinGER6, MGC21416" ENSG00000181704 "Yip1 domain family member 6" Q96EC8 X 68498562-68537282 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 332.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003720 Uncertain Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 72 Vesicles "HPA003720: AB_1080626" "unprognostic (5.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.72e-1)" "unprognostic (7.17e-2)" "unprognostic (5.90e-3)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (1.33e-2)" "unprognostic (3.15e-1)" "unprognostic (8.85e-3)" "unprognostic (8.48e-2)" "unprognostic (2.90e-2)" "unprognostic (3.25e-1)" "unprognostic (6.32e-2)" YIPF7 "FinGER9, FLJ39576" ENSG00000177752 "Yip1 domain family member 7" Q8N8F6 4 44622088-44678556 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "skeletal muscle: 66.5;tongue: 20.6" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 20 "cerebellum: 10.1" HPA030642 Uncertain NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA030642: AB_10601027" "unprognostic (9.41e-4)" "unprognostic (2.27e-1)" "unprognostic (2.90e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-2)" "unprognostic (1.34e-1)" "unprognostic (9.46e-2)" "unprognostic (9.81e-2)" "unprognostic (2.32e-2)" "unprognostic (3.05e-2)" "unprognostic (1.52e-2)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.98e-2)" YME1L1 YME1L ENSG00000136758 "YME1 like 1 ATPase" Q96TA2 10 27110111-27155266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA066953 Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 80: Non-specific - Transcription" Mitochondria "Nuclear bodies" "HPA066953: AB_2685753" "unprognostic (2.28e-3)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (7.19e-2)" "unprognostic (8.12e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (8.25e-6)" "unprognostic (7.08e-2)" "unprognostic (2.91e-1)" "unprognostic (9.24e-2)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (1.44e-2)" "unprognostic (7.09e-2)" ZBTB11 "ZNF-U69274, ZNF913" ENSG00000066422 "Zinc finger and BTB domain containing 11" O95625 3 101648889-101677135 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015328, HPA024138" Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Glandular & Luminal cells - Unknown function" Nucleoplasm "HPA015328: AB_1858938, HPA024138: AB_1858939" "unprognostic (3.25e-3)" "unprognostic (9.62e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (2.86e-2)" "unprognostic (7.04e-2)" "unprognostic (1.17e-3)" "unprognostic (4.77e-1)" "unprognostic (6.65e-3)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (1.45e-2)" "unprognostic (5.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-1)" "unprognostic (5.90e-2)" "unprognostic (2.09e-1)" ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 58.3;Late spermatids: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 14 Cytosol "HPA042531: AB_2678041, HPA048659: AB_2680483" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favorable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favorable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favorable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795605-858973 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 12.0;Early spermatids: 20.4;Excitatory neurons: 20.7;Inhibitory neurons: 15.7;Oligodendrocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA057886, HPA069008" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Ciliated cells - Cilium assembly" 1 "Golgi apparatus" "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.6;Inhibitory neurons: 36.7;Oligodendrocyte precursor cells: 25.0;Oligodendrocytes: 65.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.9" "Thyroid - Fibroblasts" "HPA057886, HPA069008" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 250.0;Proximal enterocytes: 192.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 156.3;Inhibitory neurons: 103.5;Oligodendrocyte precursor cells: 295.7;Oligodendrocytes: 205.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.4;Excitatory neurons: 17.6;Inhibitory neurons: 17.0;Oligodendrocyte precursor cells: 16.0" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.2;Rhabdoid: 2.3" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" 47 "Nuclear speckles" Cytosol "HPA003618: AB_2217686, HPA064901: " "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Uncertain "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" 2 Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 111.0;Excitatory neurons: 98.8;Inhibitory neurons: 91.1;Oligodendrocytes: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016807 Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 28: Dendritic cells - Antigen presentation" 30 "Golgi apparatus" Vesicles "HPA016807: AB_1858999" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavorable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in many" 18 "granulocytes: 49.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 74: Neutrophils - Degranulation" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 75.3" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 84.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Retina & Testis - Cilium" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21348784-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 149.6;Oligodendrocytes: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" ZDHHC21 "DHHC21, DNZ1, HSPC097" ENSG00000175893 "Zinc finger DHHC-type palmitoyltransferase 21" Q8IVQ6 9 14611071-14693432 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 212.0;Inhibitory neurons: 193.0;Oligodendrocyte precursor cells: 252.3;Oligodendrocytes: 147.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065254 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 76: Oligodendrocyte precursor - Unknown function" 10 "Golgi apparatus, Cytosol" "HPA065254: AB_2685446" "unprognostic (2.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (2.01e-1)" "unprognostic (4.19e-2)" "unprognostic (2.58e-2)" "unprognostic (2.81e-2)" "unprognostic (1.13e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (9.79e-3)" "unprognostic (3.97e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (8.87e-2)" "prognostic favorable (9.28e-6)" ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 36.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.2;Excitatory neurons: 8.5;Horizontal cells: 12.0;Inhibitory neurons: 12.8;Late spermatids: 4.9;Oligodendrocyte precursor cells: 23.1" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.6" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" 12 "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type palmitoyltransferase 23" Q8IYP9 3 113947901-113965401 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 26.3;Excitatory neurons: 69.8;Late spermatids: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA016808: AB_1859002" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (4.48e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.49e-1)" "unprognostic (3.98e-3)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (3.19e-1)" "unprognostic (6.63e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "prognostic favorable (1.48e-7)" "unprognostic (2.58e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (5.90e-4)" "unprognostic (3.29e-3)" ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546235 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" 17 "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 438.5;Late spermatids: 1574.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 1 "Nucleoplasm, Plasma membrane" "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type palmitoyltransferase 6" Q9H6R6 10 112424428-112447572 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" "HPA014357: AB_2304658" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (6.24e-2)" "unprognostic (5.21e-1)" "unprognostic (3.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (9.30e-2)" "unprognostic (8.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.22e-2)" ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" "HPA019215: AB_2670102, HPA059054: AB_2683892, HPA059642: AB_2684093" "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" ZDHHC8 "DHHC8, KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Non-specific - DNA binding" Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 164.7;Alveolar cells type 2: 94.8;Oligodendrocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 72: Alveolar cells - Lung function" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" ZFPL1 "D11S750, MCG4" ENSG00000162300 "Zinc finger protein like 1" O95159 11 65084210-65088398 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014909, HPA017347" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 32: Basophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 54 "Golgi apparatus" "HPA014909: AB_1859055, HPA017347: AB_1859056" "unprognostic (2.03e-1)" "unprognostic (5.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (2.50e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.12e-6)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" "unprognostic (3.63e-1)" "unprognostic (7.34e-2)" "prognostic favorable (2.73e-5)" "unprognostic (1.88e-1)" "unprognostic (1.44e-1)" "unprognostic (4.34e-2)" "unprognostic (6.94e-2)" ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" 23 "Nucleoplasm, Vesicles" Cytosol "HPA037523: AB_10672351, HPA069876: AB_2686218" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-2)" "unprognostic (7.15e-2)" "unprognostic (2.05e-3)" "unprognostic (5.24e-2)" "unprognostic (3.38e-3)" "prognostic favorable (7.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.26e-2)" "prognostic favorable (7.80e-4)" ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral protein, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 50000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)" ZMYM5 "MYM, ZNF198L1, ZNF237" ENSG00000132950 "Zinc finger MYM-type containing 5" Q9UJ78 13 19823482-19863649 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015544, HPA020879" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 80: Non-specific - Transcription" 1 Nucleoplasm "Golgi apparatus" "HPA015544: , HPA020879: AB_2670524" "unprognostic (4.14e-1)" "unprognostic (3.05e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (4.94e-2)" "unprognostic (9.35e-2)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-2)" ZMYM6 "Buster2, KIAA1353, MYM, ZBED7, ZNF198L4, ZNF258" ENSG00000163867 "Zinc finger MYM-type containing 6" O95789 1 34986165-35031945 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011004, HPA071865" Approved Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA011004: AB_1859075, HPA071865: AB_2686464" "prognostic favorable (1.30e-5)" "unprognostic (1.31e-1)" "unprognostic (2.16e-2)" "unprognostic (1.98e-1)" "unprognostic (3.06e-2)" "unprognostic (3.92e-2)" "unprognostic (2.11e-6)" "unprognostic (1.77e-3)" "unprognostic (4.83e-3)" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.70e-2)" "unprognostic (9.29e-2)" "unprognostic (7.15e-2)" "unprognostic (2.28e-1)" "unprognostic (1.72e-1)" "unprognostic (4.84e-3)" ZNF333 KIAA1806 ENSG00000160961 "Zinc finger protein 333" Q96JL9 19 14689801-14733746 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043973, HPA054680, HPA077662" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" Nucleoplasm Cytosol "HPA043973: AB_10961277, HPA054680: AB_2682571, HPA077662: " "unprognostic (8.16e-2)" "unprognostic (2.80e-4)" "unprognostic (5.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-2)" "unprognostic (1.45e-3)" "unprognostic (2.98e-2)" "unprognostic (2.17e-3)" "unprognostic (2.12e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-3)" "unprognostic (3.46e-2)" "unprognostic (1.32e-5)" "unprognostic (4.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.62e-1)" "unprognostic (7.06e-3)" ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" Transcription NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" 12 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931" "unprognostic (3.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.94e-2)" "unprognostic (3.91e-2)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" ZNF511-PRAP1 ENSG00000283496 "ZNF511-PRAP1 readthrough" 10 133309410-133352529 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 9.0;kidney: 8.2;liver: 29.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035360, HPA038713, HPA052451" Supported Uncertain "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931, HPA038713: AB_10673117, HPA052451: AB_2681839" ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58431736 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 1 "Nuclear speckles" "HPA043408: AB_2678466, HPA048075: AB_2680251" "unprognostic (6.06e-2)" "unprognostic (3.27e-3)" "unprognostic (3.76e-3)" "unprognostic (8.15e-3)" "unprognostic (5.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (6.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (1.90e-3)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-2)" ZNF816 ZNF816A ENSG00000180257 "Zinc finger protein 816" Q0VGE8 19 52949379-52962911 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA042466 Uncertain Approved "Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Nucleoli rim" "HPA042466: AB_10797497" "unprognostic (1.83e-2)" "unprognostic (1.90e-1)" "unprognostic (1.64e-1)" "unprognostic (4.81e-2)" "unprognostic (3.12e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-4)" "unprognostic (1.69e-1)" "unprognostic (1.33e-3)" "unprognostic (4.82e-2)" "unprognostic (1.01e-1)" "unprognostic (3.72e-2)" "unprognostic (5.36e-3)" "unprognostic (6.21e-2)" "unprognostic (5.45e-1)" "unprognostic (8.59e-2)" "unprognostic (1.39e-2)" ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883572-29057488 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 478.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 47: Astrocytes - Unknown function" 3 "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)" ZP2 ZPA ENSG00000103310 "Zona pellucida glycoprotein 2" Q05996 16 21197450-21214510 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 32.3" "Cell type enriched" "Detected in some" 5 "Oocytes: 36.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "cerebellum: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA011296 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 44: Oocytes - Unknown function" "HPA011296: AB_1859485" "unprognostic (2.35e-2)" "unprognostic (3.12e-2)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (3.44e-3)" "unprognostic (3.12e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" ZP3 "ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC" ENSG00000188372 "Zona pellucida glycoprotein 3" P21754 7 76397518-76442071 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.5" "Cell type enriched" "Detected in many" 26 "Oocytes: 1882.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 42.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054061, HPA071198" Supported "Secreted in female reproductive system" Receptor NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 59: Fallopian tube - Tissue development" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" 4 "HPA054061: AB_2682363, HPA071198: " "unprognostic (6.48e-2)" "unprognostic (3.08e-1)" "unprognostic (7.74e-2)" "unprognostic (1.59e-1)" "unprognostic (9.04e-2)" "unprognostic (2.68e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (3.10e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (1.02e-6)" "unprognostic (1.33e-1)" "unprognostic (1.42e-2)" "unprognostic (6.72e-2)" "unprognostic (2.13e-1)" ZP4 "ZP1B, ZPB, ZPB2" ENSG00000116996 "Zona pellucida glycoprotein 4" Q12836 1 237877864-237890922 "Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "ovary: 3.6" "Cell type enriched" "Detected in some" 25 "Oocytes: 176.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008547 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" 1 "HPA008547: AB_1080766" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.59e-2)" ZPLD1 ENSG00000170044 "Zona pellucida like domain containing 1" Q8TCW7 3 102099244-102479841 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.2;retina: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Ductal cells: 3.7;Early spermatids: 2.7;Late spermatids: 6.1;Muller glia cells: 14.6;Pancreatic endocrine cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 39.2" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 2.8" "Not detected" "Not detected" HPA077519 Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA077519: AB_2732349" "unprognostic (2.49e-1)" "unprognostic (2.83e-3)" "unprognostic (6.38e-3)" "unprognostic (1.88e-1)" "unprognostic (5.02e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (2.63e-1)" "unprognostic (4.63e-1)" "unprognostic (2.89e-4)" "unprognostic (4.59e-2)" "unprognostic (1.05e-3)" "unprognostic (1.97e-2)" "unprognostic (9.65e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-2)" ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Mitochondria "HPA031778: AB_10599831, HPA031790: AB_10600999" "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (6.75e-2)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.80e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "prognostic favorable (6.08e-4)" "unprognostic (1.54e-1)" "unprognostic (1.38e-3)" "unprognostic (6.09e-3)" "unprognostic (1.80e-1)" "unprognostic (9.43e-2)" "unprognostic (6.46e-2)"