Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 257.7;testis: 99.0" "Group enriched" "Detected in many" 20 "Early spermatids: 373.5;Late spermatids: 1317.0;Proximal enterocytes: 1039.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Fibroblast_1, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" Enzyme NA NA 104000000 170000000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 1563.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 984.4;Hepatocytes: 1899.1" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 204.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" Other NA NA 5940000 65000000000 "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 8 "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 93.7;placenta: 137.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 44.5;Hepatocytes: 28.4;Leydig cells: 139.1;Sertoli cells: 51.7;Smooth muscle cells: 57.7" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enriched" "Detected in many" 4 "midbrain: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.3;Rhabdoid: 6.8" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 31.7;Excitatory neurons: 51.1;Inhibitory neurons: 46.6;Oligodendrocytes: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Oligodendrocytes - Unknown function" 23 Nucleoli Cytosol "HPA008355: AB_2058277" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (9.31e-2)" "unprognostic (9.15e-3)" "unprognostic (6.90e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-3)" "unprognostic (4.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "prognostic favorable (3.44e-5)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.68e-1)" B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 89.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 132.0;Early spermatids: 265.0;Late spermatids: 179.0;Spermatocytes: 124.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved "Intracellular and membrane" Other NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 3 "HPA022957: AB_1848220" "unprognostic (3.13e-2)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.66e-3)" "unprognostic (9.82e-3)" "unprognostic (1.37e-2)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "prognostic favorable (4.14e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" B9D2 "MGC4093, MKS10, MKSR-2" ENSG00000123810 "B9 domain containing 2" Q9BPU9 19 41354417-41364165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 67.3;Distal tubular cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042229, HPA042618" Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 10 "HPA042229: AB_10959591, HPA042618: AB_10960695" "unprognostic (9.25e-2)" "unprognostic (1.82e-3)" "unprognostic (1.66e-1)" "unprognostic (9.68e-3)" "unprognostic (1.23e-1)" "unprognostic (2.19e-3)" "unprognostic (1.04e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.39e-4)" "unprognostic (2.58e-1)" "unprognostic (8.22e-3)" "unprognostic (4.50e-1)" "unprognostic (1.62e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-3)" CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 82.1" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 581.1;Rod photoreceptor cells: 277.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 39: Retina & Testis - Cilium" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 66: Photoreceptor cells - Visual perception" "HPA044124: AB_10969197" "unprognostic (1.88e-1)" "unprognostic (2.05e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-3)" "unprognostic (2.13e-2)" "unprognostic (1.10e-1)" "unprognostic (8.63e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-2)" "unprognostic (2.23e-2)" "unprognostic (7.33e-2)" "prognostic favorable (3.42e-9)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (2.18e-2)" CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.2;Early spermatids: 203.9;Late spermatids: 319.9;Rod photoreceptor cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606, HPA061504" Uncertain Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Retina & Testis - Cilium" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 4 Centrosome "Nucleoplasm, Vesicles" "HPA037605: AB_10672908, HPA037606: AB_10672498, HPA061504: AB_2732665" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (1.90e-1)" "prognostic favorable (5.93e-4)" "unprognostic (6.54e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (7.93e-2)" CEP290 "3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6" ENSG00000198707 "Centrosomal protein 290" O15078 12 88049016-88142099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Activator "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Leber congenital amaurosis, Meckel syndrome, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 214.3;Spermatocytes: 158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB029995, HPA043918, HPA064397" Approved Supported Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 9 Centrosome "CAB029995: , HPA043918: AB_2678730, HPA064397: AB_2685255" "unprognostic (7.42e-2)" "unprognostic (4.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (8.90e-2)" "unprognostic (1.45e-4)" "unprognostic (2.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.94e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.21e-6)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.44e-2)" "unprognostic (3.84e-3)" CEP83 "CCDC41, NPHP18, NY-REN-58" ENSG00000173588 "Centrosomal protein 83" Q9Y592 12 94306449-94459988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 78.9;Early spermatids: 75.2;Oligodendrocyte precursor cells: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038161 Approved NA NA "Cluster 18: Non-specific - Translation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" "HPA038161: AB_10674547" "unprognostic (4.98e-2)" "unprognostic (1.64e-2)" "unprognostic (7.22e-2)" "unprognostic (1.75e-2)" "unprognostic (4.76e-3)" "unprognostic (3.59e-2)" "unprognostic (5.44e-3)" "unprognostic (1.70e-1)" "unprognostic (2.24e-2)" "unprognostic (1.92e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.98e-4)" "prognostic unfavorable (5.00e-10)" "unprognostic (1.29e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.95e-2)" DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 20.1;kidney: 22.6;pancreas: 25.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 69.1;Collecting duct cells: 85.6;Distal tubular cells: 58.4;Ductal cells: 128.7;Glandular and luminal cells: 97.7;Oocytes: 225.0;Proximal tubular cells: 62.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 33.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 45.3;ovarian cancer: 38.7" "Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 68: Non-specific - Protein processing" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 25 Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" DNAJB11 "EDJ, ERdj3, HEDJ" ENSG00000090520 "DnaJ heat shock protein family (Hsp40) member B11" Q9UBS4 3 186567403-186585800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010814, HPA017051" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 100000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 6 "Endoplasmic reticulum" "HPA010814: AB_1078691, HPA017051: AB_1847792" "unprognostic (4.29e-1)" "unprognostic (1.07e-1)" "unprognostic (2.98e-2)" "unprognostic (2.24e-2)" "unprognostic (8.53e-2)" "unprognostic (1.07e-3)" "unprognostic (3.86e-2)" "unprognostic (6.52e-2)" "unprognostic (7.95e-2)" "unprognostic (2.14e-3)" "unprognostic (2.58e-2)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.44e-9)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.82e-1)" DSTYK "DustyPK, KIAA0472, RIP5, RIPK5, SPG23" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211702 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 120.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (8.73e-5)" DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 63.3;Early spermatids: 16.3;Rod photoreceptor cells: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 59: Fallopian tube - Tissue development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" 8 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA030404: AB_10601548" "unprognostic (3.65e-2)" "unprognostic (8.37e-2)" "unprognostic (2.87e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-2)" "unprognostic (6.50e-2)" "unprognostic (6.47e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (2.35e-3)" "unprognostic (2.72e-1)" "unprognostic (9.98e-2)" "unprognostic (2.77e-2)" FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8" "Cell type enriched" "Detected in some" 5 "Microglial cells: 8.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;Rhabdoid: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 2.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.57e-3)" "unprognostic (3.95e-2)" "unprognostic (1.59e-3)" "unprognostic (1.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.95e-2)" "unprognostic (3.92e-1)" "unprognostic (4.08e-2)" GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 23000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 4: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.2;Leydig cells: 22.6;Peritubular cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" 27 Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242232-21526112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 8.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 234.9" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 34: Testis cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" INVS NPHP2 ENSG00000119509 Inversin Q9Y283 9 100099243-100302175 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Calmodulin-binding, Developmental protein" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 126.0;Excitatory neurons: 139.9;Inhibitory neurons: 136.9;Microglial cells: 107.4;Oligodendrocyte precursor cells: 135.4;Oligodendrocytes: 217.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049994, HPA069782" Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 16: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 8: Neurons - Neuronal signaling" 2 "Plasma membrane, Cytosol" "HPA049994: , HPA069782: " "unprognostic (3.84e-3)" "unprognostic (3.11e-2)" "unprognostic (1.74e-1)" "unprognostic (2.86e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.53e-3)" "unprognostic (2.93e-3)" "unprognostic (1.99e-1)" "unprognostic (6.46e-2)" "unprognostic (1.15e-1)" "unprognostic (3.56e-2)" "unprognostic (1.34e-3)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (6.37e-2)" "unprognostic (1.83e-1)" IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 104.4;Spermatocytes: 168.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 11 "Microtubules, Cytokinetic bridge, Mitotic spindle" Nucleoplasm "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 36.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 79.7;Inhibitory neurons: 53.6;Microglial cells: 33.1;Oligodendrocyte precursor cells: 60.8;Plasma cells: 34.7;Smooth muscle cells: 106.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 13.8;Rhabdoid: 5.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.0;Gastric mucus-secreting cells: 10.6;Plasma cells: 12.3;Spermatocytes: 26.4;Spermatogonia: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cell proliferation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 122.3;Excitatory neurons: 60.1;Inhibitory neurons: 52.8;Oligodendrocytes: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 32: Basophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 48 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: AB_10601869, HPA030833: AB_2673628" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (6.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (9.84e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.08e-3)" "unprognostic (6.03e-3)" "unprognostic (7.94e-2)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" MKS1 "BBS13, FLJ20345, MKS, POC12" ENSG00000011143 "MKS transition zone complex subunit 1" Q9NXB0 17 58205441-58219605 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021372, HPA021812" Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 3 "HPA021372: AB_1848746, HPA021812: AB_2142654" "unprognostic (3.57e-1)" "unprognostic (4.12e-2)" "unprognostic (8.58e-2)" "unprognostic (3.06e-2)" "unprognostic (5.79e-2)" "unprognostic (5.05e-2)" "unprognostic (7.06e-3)" "unprognostic (6.27e-2)" "unprognostic (9.40e-2)" "unprognostic (4.64e-3)" "prognostic favorable (1.25e-4)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (9.86e-3)" "unprognostic (4.25e-1)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 419.1;stomach 1: 862.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 963.7;Alveolar cells type 2: 1456.7;Exocrine glandular cells: 951.7;Gastric mucus-secreting cells: 572.5;Ionocytes: 447.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 42.3;Endometrial stromal cells: 49.3;Peritubular cells: 102.4;Smooth muscle cells: 37.6" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 11.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "cerebellum: 5.4" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 12 Microtubules "Nuclear speckles, Mitotic spindle" "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 37.1;skeletal muscle: 35.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 134.6;Early spermatids: 179.0;Late spermatids: 63.8;Rod photoreceptor cells: 74.5;Spermatocytes: 133.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 5 "HPA046093: AB_2679535, HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" NPHP3 "CFAP31, FLJ30691, FLJ36696, KIAA2000, MKS7, NPH3, SLSN3" ENSG00000113971 "Nephrocystin 3" Q7Z494 3 132680609-132722432 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Ciliopathy, Disease variant, Meckel syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 59.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009150 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 6: Ovarian stromal cells - Transcription" 2 "HPA009150: AB_1078086" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (2.79e-1)" "unprognostic (2.22e-1)" "unprognostic (8.24e-3)" "unprognostic (2.36e-5)" "unprognostic (8.02e-3)" "unprognostic (6.51e-2)" "unprognostic (1.96e-2)" "unprognostic (9.42e-3)" "unprognostic (2.92e-2)" "prognostic unfavorable (8.28e-9)" "unprognostic (2.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-3)" NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Excitatory neurons: 45.5;Inhibitory neurons: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 78: Testis - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 34: Neurons - Neuronal signaling" 6 "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" NRIP1 RIP140 ENSG00000180530 "Nuclear receptor interacting protein 1" P48552 21 14961235-15065936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029785, HPA046571, HPA060036" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 14 "Nucleoplasm, Nucleoli" Cytosol "HPA029785: , HPA046571: AB_2679704, HPA060036: AB_2684193" "unprognostic (5.60e-2)" "unprognostic (1.87e-1)" "unprognostic (5.20e-3)" "unprognostic (4.64e-3)" "unprognostic (7.98e-2)" "unprognostic (2.59e-2)" "unprognostic (2.74e-1)" "unprognostic (2.75e-3)" "unprognostic (8.94e-3)" "unprognostic (1.55e-1)" "unprognostic (2.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-2)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (2.72e-1)" "unprognostic (2.80e-1)" PAX2 PAX-2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 29.0;kidney: 83.0" "Group enriched" "Detected in some" 4 "Collecting duct cells: 134.2;Glandular and luminal cells: 231.1" "Group enriched" "Detected in some" 19 "endometrial cancer: 6.7;ovarian cancer: 7.0;renal cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney cancer: 17.9;ovarian cancer: 5.4;Rhabdoid: 10.8;Uterine cancer: 8.5" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 6 "cerebellum: 5.2;medulla oblongata: 7.7;spinal cord: 6.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" "Developmental protein" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 Nucleoplasm "CAB013024: AB_2533990, HPA047704: AB_2636861, HPA070751: AB_2686305" "unprognostic (3.98e-2)" "unprognostic (9.55e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (4.85e-2)" "unprognostic (5.54e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (6.59e-2)" "unprognostic (9.18e-2)" "unprognostic (3.30e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (6.34e-2)" "unprognostic (8.26e-2)" PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 362.6;Excitatory neurons: 460.0;Inhibitory neurons: 387.9;Oligodendrocyte precursor cells: 307.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" 11 Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" PKD1 "PBP, Pc-1, TRPP1" ENSG00000008710 "Polycystin 1, transient receptor potential channel interacting" P98161 16 2088708-2135898 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 252.1" "Cell type enhanced" "Detected in all" "Excitatory neurons: 133.5;Horizontal cells: 85.6;Inhibitory neurons: 96.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046448 Approved NA NA 840000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "CAB046448: AB_2163360" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic favorable (3.35e-4)" "unprognostic (1.98e-2)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "prognostic favorable (3.38e-5)" "unprognostic (7.86e-2)" "unprognostic (4.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.78e-2)" "unprognostic (2.81e-1)" PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 124.7;Inhibitory neurons: 142.7;Microglial cells: 91.3;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 204.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 12 "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.6;kidney: 13.2;pancreas: 9.1" "Group enriched" "Detected in some" 5 "Early spermatids: 370.0;Late spermatids: 97.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.1;Kidney cancer: 2.0" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "kidney: 157.7" "Group enriched" "Detected in some" 5 "Club cells: 33.8;Late spermatids: 27.8;Smooth muscle cells: 14.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enhanced" "Detected in many" "choroid plexus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 22.1;colorectal cancer: 8.4" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" Enzyme NA NA 692000 10000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" 2 "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 13.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 45.8;Excitatory neurons: 57.8;Inhibitory neurons: 35.1;Spermatocytes: 39.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium assembly" 9 "Plasma membrane, Cytosol" "HPA039405: AB_10794636, HPA040530: AB_2677023" "prognostic unfavorable (6.93e-4)" "unprognostic (1.52e-1)" "unprognostic (2.19e-3)" "unprognostic (2.26e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-4)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (5.22e-3)" "unprognostic (1.52e-1)" "unprognostic (4.92e-4)" "unprognostic (5.95e-2)" SDCCAG8 "BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7" ENSG00000054282 "SHH signaling and ciliogenesis regulator SDCCAG8" Q86SQ7 1 243256034-243500091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 264.3;Oocytes: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025737, HPA044477, HPA072495" Approved Enhanced Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 4 Centrosome "HPA025737: AB_2671761, HPA044477: AB_2678955, HPA072495: AB_2686527" "unprognostic (4.12e-1)" "unprognostic (3.94e-2)" "unprognostic (7.58e-2)" "unprognostic (2.86e-2)" "unprognostic (2.61e-1)" "unprognostic (3.78e-2)" "unprognostic (9.34e-2)" "unprognostic (3.95e-2)" "unprognostic (4.37e-2)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-2)" "unprognostic (1.38e-3)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (3.68e-3)" "unprognostic (4.69e-2)" SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 95.9;pancreas: 59.7;tongue: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 26 Mitochondria "HPA014721: , HPA015138: AB_1857160" "unprognostic (1.18e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.77e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (5.23e-2)" "unprognostic (5.53e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (4.46e-2)" "unprognostic (3.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.9" "Cell type enriched" "Detected in some" 4 "Microglial cells: 87.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006807 Supported Nucleoplasm NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 4 Nucleoplasm "HPA006807: " "unprognostic (8.04e-2)" "unprognostic (7.06e-3)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (2.57e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-14)" "unprognostic (4.81e-5)" "unprognostic (1.86e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 38.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 26.1;Cone photoreceptor cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Uncertain "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 8 "Golgi apparatus" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 55.1" "Cell type enhanced" "Detected in all" "Ciliated cells: 122.6;Cone photoreceptor cells: 117.2;Plasma cells: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 32: Basophils - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 38 "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" TMEM216 "CORS2, HSPC244, JBTS2, MGC13379, MKS2" ENSG00000187049 "Transmembrane protein 216" Q9P0N5 11 61392393-61398866 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 232.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 59: Fallopian tube - Tissue development" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (7.75e-2)" "unprognostic (1.54e-1)" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (9.02e-3)" "unprognostic (4.44e-2)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-2)" "unprognostic (9.66e-2)" "unprognostic (2.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (8.03e-3)" TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556289 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "choroid plexus: 39.3;fallopian tube: 71.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 130.5;Rod photoreceptor cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved Vesicles NA NA "Cluster 18: Non-specific - Translation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium assembly" 7 Vesicles "HPA042081: AB_10795391" "unprognostic (4.29e-2)" "unprognostic (9.84e-2)" "unprognostic (8.07e-2)" "unprognostic (2.71e-3)" "unprognostic (1.03e-1)" "unprognostic (9.34e-2)" "unprognostic (2.90e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (1.69e-2)" "unprognostic (3.34e-3)" "unprognostic (7.84e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 97.0;Excitatory neurons: 57.8;Rod photoreceptor cells: 82.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 17: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Ciliated cells - Cilium assembly" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 134.4;Early spermatids: 87.9;Late spermatids: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Ciliated cells - Cilium assembly" 10 "HPA037857: AB_2675706, HPA037858: AB_10671724" "unprognostic (1.25e-1)" "unprognostic (9.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.80e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (9.04e-2)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (4.78e-3)" "unprognostic (7.48e-3)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.07e-1)" TTC21B "FAP60, FLA17, FLJ11457, IFT139, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073293 Supported Approved "Centriolar satellite,Cytosol" NA No "Cluster 14: Non-specific - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Ciliated cells - Cilium assembly" 9 "Centriolar satellite" Cytosol "HPA073293: " "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" "unprognostic (1.60e-2)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "unprognostic (7.09e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (7.57e-2)" "unprognostic (3.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.84e-2)" TXNDC15 "2310047H23Rik, C5orf14, FLJ22625" ENSG00000113621 "Thioredoxin domain containing 15" Q96J42 5 134874371-134901635 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015483 Approved Approved "Golgi apparatus" NA NA 49000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "HPA015483: AB_1845722" "unprognostic (1.56e-1)" "unprognostic (1.22e-2)" "unprognostic (2.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.68e-2)" "unprognostic (9.71e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.36e-1)" "unprognostic (4.37e-1)" "unprognostic (1.41e-3)" "unprognostic (1.50e-1)" UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 689 "kidney: 2197.0" "Group enriched" "Detected in some" 164 "Collecting duct cells: 204.2;Distal tubular cells: 405.7" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" Immunity NA NA 55000000 66000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 41.4;Excitatory neurons: 59.6;Inhibitory neurons: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 59: Fallopian tube - Tissue development" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 12 Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 188.8;Late spermatids: 322.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved Supported Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" 4 Mitochondria Cytosol "HPA000527: AB_1079266" "prognostic unfavorable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.24e-1)" ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Late spermatids: 111.5;Leydig cells: 27.3;Microglial cells: 51.0;Oligodendrocyte precursor cells: 36.3;Peritubular cells: 49.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.7;testis cancer: 16.2" "Colon - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 3 Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-3)" "unprognostic (3.37e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.77e-1)" "unprognostic (9.13e-2)" "unprognostic (8.97e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.92e-2)" "unprognostic (5.84e-2)"