Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" KCNA1 "AEMK, HUK1, Kv1.1, MBK1, RBK1" ENSG00000111262 "Potassium voltage-gated channel subfamily A member 1" Q09470 12 4909905-4918256 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "brain: 52.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.8;Excitatory neurons: 38.3;Horizontal cells: 21.4;Inhibitory neurons: 17.9;Oligodendrocyte precursor cells: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074471 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA074471: " "unprognostic (6.39e-3)" "unprognostic (2.64e-1)" "unprognostic (1.09e-1)" "unprognostic (8.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-2)" "unprognostic (4.69e-3)" "unprognostic (2.48e-1)" "unprognostic (8.77e-5)" "unprognostic (6.30e-2)" "unprognostic (1.08e-4)" KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 32.1;retina: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 47.4;Early spermatids: 16.9;Excitatory neurons: 35.5;Horizontal cells: 33.4;Inhibitory neurons: 35.6;Muller glia cells: 15.6;Oligodendrocyte precursor cells: 34.0" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Group enriched" "Detected in some" 5 "Bone cancer: 8.0;Myeloma: 3.0" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 1 "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110653560-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lung: 2.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 12.7;Inhibitory neurons: 57.6;Plasma cells: 49.8;T-cells: 24.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 5.6;MAIT T-cell: 5.3;memory CD4 T-cell: 8.5;memory CD8 T-cell: 9.6;naive B-cell: 2.6;naive CD4 T-cell: 5.0;naive CD8 T-cell: 4.6;T-reg: 8.5" "Group enriched" "Detected in many" 6 "B-cells: 2.6;T-cells: 9.6" "Cancer enriched" "Detected in some" 5 "Myeloma: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Skin - T-cells, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 2 "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4, PCN2" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.9;brain: 7.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.7;Cardiomyocytes: 3.5;Excitatory neurons: 7.9;Horizontal cells: 6.9;Mesothelial cells: 6.8;Muller glia cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001977, HPA016422" Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 3 "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043879-5046788 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 59.0;heart muscle: 38.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 128.0;Cardiomyocytes: 21.5;dendritic cells: 18.9;Horizontal cells: 34.0;Smooth muscle cells: 29.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Region enriched" "Detected in all" 7 "choroid plexus: 113.8" "Immune cell enriched" "Detected in single" 122 "plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 122 "dendritic cells: 12.2" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021516, CAB022562" Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" 2 "CAB022562: , HPA021516: AB_2670732" "unprognostic (3.87e-1)" "unprognostic (9.91e-3)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (7.06e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (5.08e-3)" "unprognostic (6.73e-4)" "unprognostic (1.92e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (3.08e-2)" KCNA6 "HBK2, Kv1.6, PPP1R96" ENSG00000151079 "Potassium voltage-gated channel subfamily A member 6" P17658 12 4809334-4813318 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 9.4" "Group enriched" "Detected in some" 8 "Astrocytes: 13.3;Excitatory neurons: 26.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 2.3;testis cancer: 7.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076475 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" Vesicles "HPA076475: " KCNA7 "HAK6, Kv1.7" ENSG00000104848 "Potassium voltage-gated channel subfamily A member 7" Q96RP8 19 49067397-49072699 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 53 "skeletal muscle: 76.8;tongue: 19.8" "Cell type enriched" "Detected in some" 33 "Skeletal myocytes: 57.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075990 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" "HPA075990: " "unprognostic (2.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.72e-1)" "unprognostic (1.68e-1)" "unprognostic (4.31e-2)" "unprognostic (3.17e-2)" "unprognostic (6.97e-2)" "unprognostic (2.94e-2)" "unprognostic (1.26e-1)" "unprognostic (2.21e-8)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (5.80e-2)" "unprognostic (5.29e-2)" KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 111.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.9;Cone photoreceptor cells: 309.2;Excitatory neurons: 145.6;Inhibitory neurons: 85.9;Rod photoreceptor cells: 352.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5;Rhabdoid: 4.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;lymphoid tissue: 2.2;retina: 4.4" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 178.4;Excitatory neurons: 269.5;Inhibitory neurons: 230.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 102.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Excitatory neurons: 46.6;Horizontal cells: 272.6;Inhibitory neurons: 115.5" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" KCNC2 Kv3.2 ENSG00000166006 "Potassium voltage-gated channel subfamily C member 2" Q96PR1 12 75040077-75209839 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.8" "Group enriched" "Detected in some" 10 "Excitatory neurons: 377.2;Inhibitory neurons: 1368.9" "Group enriched" "Detected in some" 8 "breast cancer: 1.5;prostate cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;Sarcoma: 1.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019664, CAB022571" Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "CAB022571: , HPA019664: AB_1855578" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (5.58e-3)" "unprognostic (4.46e-2)" "unprognostic (3.39e-2)" KCNC3 "Kv3.3, SCA13" ENSG00000131398 "Potassium voltage-gated channel subfamily C member 3" Q14003 19 50311937-50333515 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.2;thyroid gland: 50.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 19.4;Excitatory neurons: 15.1;Glandular and luminal cells: 14.9;Inhibitory neurons: 17.6;monocytes: 16.5;Secretory cells: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018041 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA018041: AB_1855579" "unprognostic (8.05e-2)" "unprognostic (2.34e-2)" "unprognostic (3.01e-4)" "unprognostic (4.41e-2)" "unprognostic (3.84e-2)" "unprognostic (1.91e-2)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (3.94e-3)" "unprognostic (2.10e-5)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-2)" "unprognostic (1.19e-1)" KCNC4 "C1orf30, HKSHIIIC, Kv3.4" ENSG00000116396 "Potassium voltage-gated channel subfamily C member 4" Q03721 1 110210314-110283100 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 43.2;Sertoli cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014740 Approved Nucleoli,Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nucleoli, Cytosol" "HPA014740: AB_1855580" "unprognostic (9.16e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-2)" "unprognostic (3.72e-1)" "unprognostic (4.12e-2)" "unprognostic (6.13e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (2.03e-1)" "unprognostic (4.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.25e-2)" KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;Peritubular cells: 4.0;Rod photoreceptor cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA000524: AB_2666013, HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favorable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273175-120750337 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 36.3" "Group enriched" "Detected in some" 11 "Excitatory neurons: 667.4;Inhibitory neurons: 1026.1;Oligodendrocyte precursor cells: 1832.4" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.9" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA029068: AB_10601436" "unprognostic (4.22e-1)" "unprognostic (2.79e-4)" "unprognostic (3.79e-2)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-3)" "unprognostic (9.07e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.77e-3)" "unprognostic (1.51e-1)" "unprognostic (4.51e-4)" "unprognostic (4.07e-5)" "unprognostic (2.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.83e-3)" KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.6;Cardiomyocytes: 36.9;Excitatory neurons: 102.1;Hepatocytes: 32.7;Horizontal cells: 40.9;Inhibitory neurons: 84.6;Late spermatids: 34.4;Oligodendrocyte precursor cells: 42.9" "Cancer enhanced" "Detected in many" "prostate cancer: 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "brain: 46.8;choroid plexus: 24.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.0;Extravillous trophoblasts: 17.6;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 17.0;Syncytiotrophoblasts: 7.5" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 11.5;lung cancer: 9.0" "Breast - Breast glandular cells (progenitors), Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 9 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "endometrium 1: 84.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.0;Early spermatids: 19.2;Late spermatids: 21.2;Syncytiotrophoblasts: 82.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 72 "B-cells: 7.1" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 17.3;basal ganglia: 15.0;cerebral cortex: 29.9;hippocampal formation: 22.6" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79797938-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.0" "Cell type enhanced" "Detected in some" "dendritic cells: 28.0;Excitatory neurons: 18.6;Horizontal cells: 27.1;Inhibitory neurons: 29.9;Oocytes: 75.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "hippocampal formation: 24.5" HPA048628 Enhanced NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 69: Neurons - Neuronal signaling" "HPA048628: AB_2680466" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-1)" "unprognostic (1.99e-1)" "unprognostic (9.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (3.78e-1)" "unprognostic (3.61e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-5)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" KCNG3 Kv6.3 ENSG00000171126 "Potassium voltage-gated channel modifier subfamily G member 3" Q8TAE7 2 42442017-42493982 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 15.8;Glandular and luminal cells: 10.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 7.1" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041625 Approved "Cytoplasmic bodies" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Cytoplasmic bodies" "HPA041625: " "unprognostic (1.56e-1)" "unprognostic (4.22e-3)" "unprognostic (2.48e-1)" "unprognostic (7.67e-3)" "unprognostic (7.95e-2)" "unprognostic (9.14e-3)" "unprognostic (4.83e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (2.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (2.76e-1)" "unprognostic (6.47e-2)" "unprognostic (1.23e-1)" KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218657-84240012 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "retina: 3.8" "Cell type enriched" "Detected in some" 10 "Bipolar cells: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA063516: " "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 516.4;Inhibitory neurons: 249.8;Oligodendrocytes: 108.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Adrenocortical cancer: 20.7" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;retina: 4.3" "Group enriched" "Detected in some" 11 "Bipolar cells: 47.3;Excitatory neurons: 178.8;Horizontal cells: 51.0;Inhibitory neurons: 71.0;Oligodendrocyte precursor cells: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;cervical cancer: 1.2" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Centrosome "Nucleoplasm, Cytosol" "HPA030487: AB_10609995, HPA072351: " "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (8.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.7;kidney: 6.8;pituitary gland: 5.2;prostate: 3.8;retina: 4.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.1;Cone photoreceptor cells: 11.9;Enteroendocrine cells: 27.3;Horizontal cells: 11.3;Prostatic glandular cells: 24.5;Proximal enterocytes: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.2;lung cancer: 9.7;prostate cancer: 5.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.4;olfactory bulb: 3.2;spinal cord: 3.2" HPA061704 Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838767 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;retina: 1.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 663.4;Inhibitory neurons: 337.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 5 "amygdala: 21.6;cerebral cortex: 85.1;hippocampal formation: 55.9;olfactory bulb: 53.9" HPA018039 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA018039: AB_1852125" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.66e-1)" "unprognostic (5.55e-2)" "unprognostic (3.05e-2)" "unprognostic (5.51e-2)" "unprognostic (8.12e-3)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.55e-3)" "unprognostic (2.76e-3)" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.68e-2)" KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;pituitary gland: 10.4;retina: 3.3" "Group enriched" "Detected in many" 39 "Oligodendrocyte precursor cells: 311.3;Oligodendrocytes: 921.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.0;Neuroblastoma: 2.4" "Colon - Enteric glia cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 191.0;stomach 1: 96.2" "Cell type enhanced" "Detected in many" "Microglial cells: 68.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 32.2;Gastric cancer: 20.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Endoplasmic reticulum" "Plasma membrane" "HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 136.8" "Group enriched" "Detected in some" 5 "Early spermatids: 19.5;Excitatory neurons: 59.7;Horizontal cells: 30.2;Inhibitory neurons: 35.9;Oligodendrocyte precursor cells: 47.6;Spermatogonia: 31.1" "Cancer enriched" "Detected in some" 9 "glioma: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.5;Neuroblastoma: 51.2" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA016642: AB_1855555, HPA057112: AB_2683339" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-4)" "unprognostic (8.21e-6)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (6.06e-2)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (9.96e-2)" "unprognostic (9.39e-2)" "unprognostic (1.43e-5)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" KCNQ4 "DFNA2, Kv7.4" ENSG00000117013 "Potassium voltage-gated channel subfamily Q member 4" P56696 1 40783787-40840452 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Hearing, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 5.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.9;Inhibitory neurons: 9.3;Muller glia cells: 3.4;Skeletal myocytes: 5.9;Smooth muscle cells: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018305 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA018305: AB_1855556" "unprognostic (1.42e-2)" "unprognostic (1.56e-1)" "unprognostic (8.43e-3)" "unprognostic (4.59e-3)" "unprognostic (8.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (5.86e-2)" "unprognostic (4.34e-2)" "unprognostic (6.64e-2)" "unprognostic (1.20e-1)" "unprognostic (7.40e-2)" "unprognostic (5.18e-4)" "unprognostic (2.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (3.44e-2)" KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 15.7;tongue: 11.3" "Group enriched" "Detected in some" 12 "Excitatory neurons: 2066.7;Inhibitory neurons: 827.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Uncertain "Cytoplasmic bodies" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" "Cytoplasmic bodies" "HPA016655: AB_1855557" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (4.96e-2)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (6.09e-2)" "unprognostic (8.55e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.16e-2)" "unprognostic (1.39e-3)" KCNS2 Kv9.2 ENSG00000156486 "Potassium voltage-gated channel modifier subfamily S member 2" Q9ULS6 8 98426958-98432853 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.9;Excitatory neurons: 4.3;Horizontal cells: 3.1;Inhibitory neurons: 1.6;Leydig cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051417 Uncertain NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA051417: AB_2681478" "unprognostic (7.83e-2)" "unprognostic (9.39e-3)" "unprognostic (5.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (4.27e-2)" "unprognostic (4.58e-2)" "unprognostic (1.47e-1)" "unprognostic (5.30e-5)" "unprognostic (2.43e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-3)" KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 83.0;tongue: 43.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "brain: 13.1" "Cell type enriched" "Detected in some" 10 "Excitatory neurons: 27.3" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 48.0" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717510-2730037 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 280.3" "Group enriched" "Detected in some" 10 "Cone photoreceptor cells: 1522.4;Rod photoreceptor cells: 472.1" "Cancer enriched" "Detected in single" 78 "testis cancer: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA031131: AB_10609996" "unprognostic (5.06e-2)" "unprognostic (1.47e-3)" "unprognostic (3.45e-3)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.12e-3)" "unprognostic (5.38e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.35e-1)" "unprognostic (7.96e-8)" "unprognostic (3.01e-1)" "unprognostic (4.90e-2)" "unprognostic (9.90e-2)" "unprognostic (1.06e-2)"